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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 2.5.1.21 (squalene synthase) inhibitor
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Accession:CHEBI:75174 term browser browse the term
Definition:An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of squalene synthase (EC 2.5.1.21).
Synonyms:related_synonym: EC 2.5.1.21 inhibitor;   EC 2.5.1.21 inhibitors;   SQS inhibitor;   SQS inhibitors;   farnesyl-diphosphate farnesyltransferase inhibitor;   farnesyl-diphosphate farnesyltransferase inhibitors;   farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitor;   farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitors;   farnesyltransferase inhibitor;   farnesyltransferase inhibitors;   presqualene synthase inhibitor;   presqualene synthase inhibitors;   presqualene-diphosphate synthase inhibitor;   presqualene-diphosphate synthase inhibitors;   squalene synthase (EC 2.5.1.21) inhibitors;   squalene synthase inhibitor;   squalene synthase inhibitors;   squalene synthetase inhibitor;   squalene synthetase inhibitors
 xref: Wikipedia:Squalene_synthase



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd3 ATP binding cassette subfamily D member 3 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of ABCD3 mRNA
squalestatin 1 results in increased expression of ABCD3 mRNA
CTD PMID:27225895 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO
EXP
squalestatin 1 results in increased expression of ACAA1B mRNA CTD PMID:27225895 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of ACAA2 mRNA
squalestatin 1 results in increased expression of ACAA2 mRNA
CTD PMID:27225895 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of ACAT1 mRNA
squalestatin 1 results in decreased expression of ACAT1 mRNA
CTD PMID:27225895 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acly ATP citrate lyase decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of ACLY mRNA
squalestatin 1 results in increased expression of ACLY mRNA
CTD PMID:27225895 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression EXP
ISO
squalestatin 1 results in increased expression of ACOT1 mRNA CTD PMID:27225895 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO
EXP
squalestatin 1 results in increased expression of ACOT2 mRNA CTD PMID:27225895 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression EXP
ISO
squalestatin 1 results in increased expression of ACOT3 mRNA CTD PMID:27225895 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression ISO
EXP
squalestatin 1 results in increased expression of ACOT4 mRNA CTD PMID:27225895 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of ACOX1 mRNA
squalestatin 1 affects the expression of ACOX1 mRNA
CTD PMID:27225895 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of ACSF2 mRNA
squalestatin 1 results in increased expression of ACSF2 mRNA
CTD PMID:27225895 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of ACSL1 mRNA
squalestatin 1 affects the expression of ACSL1 mRNA
CTD PMID:27225895 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of ACTA1 mRNA
squalestatin 1 results in increased expression of ACTA1 mRNA
CTD PMID:27225895 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Adamdec1 ADAM-like, decysin 1 decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of ADAMDEC1 mRNA
squalestatin 1 affects the expression of ADAMDEC1 mRNA
CTD PMID:27225895 NCBI chr15:42,900,629...42,923,136
Ensembl chr15:42,900,636...42,921,712
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of ADH7 mRNA
squalestatin 1 results in increased expression of ADH7 mRNA
CTD PMID:27225895 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Agt angiotensinogen decreases expression
affects expression
ISO
EXP
squalestatin 1 results in decreased expression of AGT mRNA
squalestatin 1 affects the expression of AGT mRNA
CTD PMID:27225895 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of AIF1 mRNA CTD PMID:27225895 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of AKR1C3 mRNA
squalestatin 1 affects the expression of AKR1C18 mRNA
CTD PMID:27225895 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP
ISO
squalestatin 1 results in increased expression of ALDH1A1 mRNA CTD PMID:27225895 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of ALDH1A3 mRNA CTD PMID:27225895 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldoart2 aldolase 1 A retrogene 2 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of ALDOART2 mRNA
squalestatin 1 results in decreased expression of ALDOART2 mRNA
CTD PMID:27225895 NCBI chr 6:72,939,821...72,941,511
Ensembl chr 6:72,939,788...72,941,709
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO
EXP
squalestatin 1 results in increased expression of AMPD3 mRNA CTD PMID:27225895 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of ANGPTL3 mRNA CTD PMID:27225895 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Ank2 ankyrin 2 increases expression EXP squalestatin 1 results in increased expression of ANK2 mRNA CTD PMID:27225895 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Anks6 ankyrin repeat and sterile alpha motif domain containing 6 decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of ANKS6 mRNA
squalestatin 1 results in increased expression of ANKS6 mRNA
CTD PMID:27225895 NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596
JBrowse link
G Arg2 arginase 2 increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of ARG2 mRNA
squalestatin 1 results in decreased expression of ARG2 mRNA
CTD PMID:27225895 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression EXP
ISO
squalestatin 1 results in decreased expression of ARHGAP11A mRNA CTD PMID:27225895 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of ARRDC3 mRNA CTD PMID:27225895 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Art4 ADP-ribosyltransferase 4 increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of ART4 mRNA
squalestatin 1 results in decreased expression of ART4 mRNA
CTD PMID:27225895 NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of ATP6V0D2 mRNA
squalestatin 1 affects the expression of ATP6V0D2 mRNA
CTD PMID:27225895 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Aunip aurora kinase A and ninein interacting protein decreases expression EXP
ISO
squalestatin 1 results in decreased expression of AUNIP mRNA CTD PMID:27225895 NCBI chr 5:146,722,157...146,736,233
Ensembl chr 5:146,722,337...146,736,501
JBrowse link
G Axin2 axin 2 affects expression EXP
ISO
squalestatin 1 affects the expression of AXIN2 mRNA CTD PMID:27225895 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of BARD1 mRNA CTD PMID:27225895 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of BHLHA15 mRNA CTD PMID:27225895 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
JBrowse link
G Bmal2 basic helix-loop-helix ARNT like 2 decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of BMAL2 mRNA
squalestatin 1 affects the expression of ARNTL2 mRNA
CTD PMID:27225895 NCBI chr 4:179,699,432...179,747,710
Ensembl chr 4:179,699,502...179,746,949
JBrowse link
G Bmper BMP-binding endothelial regulator decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of BMPER mRNA
squalestatin 1 affects the expression of BMPER mRNA
CTD PMID:27225895 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression EXP
ISO
squalestatin 1 results in decreased expression of BUB1B mRNA CTD PMID:27225895 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C1qtnf6 C1q and TNF related 6 decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of C1QTNF6 mRNA
squalestatin 1 results in increased expression of C1QTNF6 mRNA
CTD PMID:27225895 NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
JBrowse link
G C5ar1 complement C5a receptor 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of C5AR1 mRNA CTD PMID:27225895 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Ccl12 C-C motif chemokine ligand 12 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of CCL12 mRNA CTD PMID:27225895 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CCL6 mRNA CTD PMID:27225895 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CCNA2 mRNA CTD PMID:27225895 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CCNB1 mRNA CTD PMID:27225895 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CCNB2 mRNA CTD PMID:27225895 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CCNE2 mRNA CTD PMID:27225895 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd209a CD209a molecule decreases expression ISO squalestatin 1 results in decreased expression of CD209 mRNA CTD PMID:27225895 NCBI chr12:1,822,663...1,828,246
Ensembl chr12:1,822,663...1,828,246
JBrowse link
G Cd209d CD209d molecule decreases expression EXP squalestatin 1 results in decreased expression of CD209 mRNA CTD PMID:27225895 NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171
JBrowse link
G Cd28 Cd28 molecule increases expression ISO
EXP
squalestatin 1 results in increased expression of CD28 mRNA CTD PMID:27225895 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule affects expression ISO
EXP
squalestatin 1 affects the expression of CD40 mRNA CTD PMID:27225895 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd48 Cd48 molecule decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CD48 mRNA CTD PMID:27225895 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
JBrowse link
G Cd7 Cd7 molecule decreases expression EXP
ISO
squalestatin 1 results in decreased expression of CD7 mRNA CTD PMID:27225895 NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967
JBrowse link
G Cdc27 cell division cycle 27 decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of CDC27 mRNA
squalestatin 1 affects the expression of CDC27 mRNA
CTD PMID:27225895 NCBI chr10:89,400,931...89,449,823
Ensembl chr10:89,400,940...89,449,736
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CDC6 mRNA CTD PMID:27225895 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdca7l cell division cycle associated 7 like decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CDCA7L mRNA CTD PMID:27225895 NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CDK1 mRNA CTD PMID:27225895 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 increases expression EXP
ISO
squalestatin 1 results in increased expression of CDS1 mRNA CTD PMID:27225895 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of CEBPD mRNA
squalestatin 1 affects the expression of CEBPD mRNA
CTD PMID:27225895 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cers6 ceramide synthase 6 increases expression ISO
EXP
squalestatin 1 results in increased expression of CERS6 mRNA CTD PMID:27225895 NCBI chr 3:53,630,636...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cesl1 carboxylesterase-like 1 increases expression EXP squalestatin 1 results in increased expression of CESL1 mRNA CTD PMID:27225895 NCBI chr19:22,670,709...23,006,329
Ensembl chr19:22,670,712...22,712,608
JBrowse link
G Cip2a cellular inhibitor of PP2A decreases expression EXP squalestatin 1 results in decreased expression of CIP2A mRNA CTD PMID:27225895 NCBI chr11:51,792,143...51,823,016
Ensembl chr11:51,795,024...51,822,938
JBrowse link
G Clca2 chloride channel accessory 2 increases expression EXP
ISO
squalestatin 1 results in increased expression of CLCA2 mRNA CTD PMID:27225895 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression EXP
ISO
squalestatin 1 results in increased expression of CLCN6 mRNA CTD PMID:27225895 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clspn claspin decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of CLSPN mRNA
squalestatin 1 results in increased expression of CLSPN mRNA
CTD PMID:27225895 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
JBrowse link
G Clstn3 calsyntenin 3 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of CLSTN3 mRNA
squalestatin 1 results in increased expression of CLSTN3 mRNA
CTD PMID:27225895 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
JBrowse link
G Cnn1 calponin 1 decreases expression
affects expression
ISO
EXP
squalestatin 1 results in decreased expression of CNN1 mRNA
squalestatin 1 affects the expression of CNN1 mRNA
CTD PMID:27225895 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of CPT1B mRNA
squalestatin 1 affects the expression of CPT1B mRNA
CTD PMID:27225895 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP
ISO
squalestatin 1 results in increased expression of CPT2 mRNA CTD PMID:27225895 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP
ISO
squalestatin 1 results in increased expression of CRAT mRNA CTD PMID:27225895 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression ISO
EXP
squalestatin 1 results in increased expression of CREB3L3 mRNA CTD PMID:27225895 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Crp C-reactive protein affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of CRP mRNA
squalestatin 1 results in increased expression of CRP mRNA
CTD PMID:27225895 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of CSMD1 mRNA
squalestatin 1 affects the expression of CSMD1 mRNA
CTD PMID:27225895 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP squalestatin 1 results in decreased expression of CXCL1 mRNA CTD PMID:27225895 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of CXCL2 mRNA CTD PMID:27225895 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO squalestatin 1 results in decreased expression of CXCL1 mRNA CTD PMID:27225895 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression EXP
ISO
squalestatin 1 results in increased expression of CXCL9 mRNA CTD PMID:27225895 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO
EXP
squalestatin 1 results in increased expression of CYP1A2 mRNA CTD PMID:27225895 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of CYP1B1 mRNA
squalestatin 1 results in decreased expression of CYP1B1 mRNA
CTD PMID:27225895 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO squalestatin 1 results in increased expression of CYP2B10 mRNA CTD PMID:27225895 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 increases expression EXP squalestatin 1 results in increased expression of CYP2B21 mRNA CTD PMID:27225895 NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP squalestatin 1 results in increased expression of CYP2J4 mRNA CTD PMID:27225895 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP squalestatin 1 results in increased expression of CYP3A23-3A1 mRNA CTD PMID:27225895 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP squalestatin 1 results in increased expression of CYP4A1 mRNA CTD PMID:27225895 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP squalestatin 1 results in increased expression of CYP4A2 mRNA CTD PMID:27225895 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP squalestatin 1 results in increased expression of CYP4A3 mRNA CTD PMID:27225895 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO
EXP
squalestatin 1 results in increased expression of CYP51 mRNA CTD PMID:27225895 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression
decreases activity
EXP squalestatin 1 results in decreased expression of CYP7B1 mRNA
squalestatin 1 results in decreased activity of CYP7B1 protein
CTD PMID:12029625 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of DECR1 mRNA
squalestatin 1 results in increased expression of DECR1 mRNA
CTD PMID:27225895 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression EXP
ISO
squalestatin 1 results in decreased expression of DEPDC1B mRNA CTD PMID:27225895 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
JBrowse link
G Derl3 derlin 3 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of DERL3 mRNA CTD PMID:27225895 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
JBrowse link
G Dnase2b deoxyribonuclease 2 beta affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of DNASE2B mRNA
squalestatin 1 results in increased expression of DNASE2B mRNA
CTD PMID:27225895 NCBI chr 2:235,470,915...235,515,211
Ensembl chr 2:235,470,919...235,486,295
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO
EXP
squalestatin 1 results in increased expression of DPYSL2 mRNA CTD PMID:27225895 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO
EXP
squalestatin 1 results in decreased expression of DTL mRNA CTD PMID:27225895 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO
EXP
squalestatin 1 results in increased expression of ECH1 mRNA CTD PMID:27225895 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP
ISO
squalestatin 1 results in increased expression of EHHADH mRNA CTD PMID:27225895 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 increases expression EXP
ISO
squalestatin 1 results in increased expression of ENPP5 mRNA CTD PMID:27225895 NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of ENTPD2 mRNA
squalestatin 1 results in decreased expression of ENTPD2 mRNA
CTD PMID:27225895 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of EPB41L3 mRNA CTD PMID:27225895 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607
JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of EPHX2 mRNA
squalestatin 1 results in increased expression of EPHX2 mRNA
CTD PMID:27225895 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Ephx4 epoxide hydrolase 4 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of EPHX4 mRNA CTD PMID:27225895 NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of ESCO2 mRNA CTD PMID:27225895 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Evi2a ecotropic viral integration site 2A decreases expression ISO
EXP
squalestatin 1 results in decreased expression of EVI2A mRNA CTD PMID:27225895 NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843
JBrowse link
G F13a1 coagulation factor XIII A1 chain affects expression EXP
ISO
squalestatin 1 affects the expression of F13A1 mRNA CTD PMID:27225895 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of FABP1 mRNA
squalestatin 1 affects the expression of FABP1 mRNA
CTD PMID:27225895 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO
EXP
squalestatin 1 results in increased expression of FABP5 mRNA CTD PMID:27225895 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO
EXP
squalestatin 1 results in decreased expression of FAM83D mRNA CTD PMID:27225895 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Far1 fatty acyl CoA reductase 1 increases expression EXP
ISO
squalestatin 1 results in increased expression of FAR1 mRNA CTD PMID:27225895 NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
JBrowse link
G Fbn1 fibrillin 1 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of FBN1 mRNA
squalestatin 1 results in decreased expression of FBN1 mRNA
CTD PMID:27225895 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression EXP squalestatin 1 results in increased expression of FBP2 mRNA CTD PMID:27225895 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G Fbxo5 F-box protein 5 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of FBXO5 mRNA CTD PMID:27225895 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fgf13 fibroblast growth factor 13 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of FGF13 mRNA
squalestatin 1 results in decreased expression of FGF13 mRNA
CTD PMID:27225895 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of FLACC1 mRNA CTD PMID:27225895 NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of FMO3 mRNA
squalestatin 1 results in decreased expression of FMO3 mRNA
CTD PMID:27225895 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Folr2 folate receptor beta decreases expression ISO
EXP
squalestatin 1 results in decreased expression of FOLR2 mRNA CTD PMID:27225895 NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724
JBrowse link
G Gck glucokinase decreases expression EXP squalestatin 1 results in decreased expression of GCK mRNA CTD PMID:27225895 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of GCNT2 mRNA
squalestatin 1 results in decreased expression of GCNT2 mRNA
CTD PMID:27225895 NCBI chr17:23,796,859...23,901,625
NCBI chr17:23,866,602...23,868,691
Ensembl chr17:23,796,859...23,901,611
JBrowse link
G Gdf10 growth differentiation factor 10 increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of GDF10 mRNA
squalestatin 1 results in decreased expression of GDF10 mRNA
CTD PMID:27225895 NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
JBrowse link
G Gdf2 growth differentiation factor 2 increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of GDF2 mRNA
squalestatin 1 results in decreased expression of GDF2 mRNA
CTD PMID:27225895 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Gldc glycine decarboxylase affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of GLDC mRNA
squalestatin 1 results in increased expression of GLDC mRNA
CTD PMID:27225895 NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of GSTK1 mRNA
squalestatin 1 affects the expression of GSTK1 mRNA
CTD PMID:27225895 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of HADH mRNA
squalestatin 1 affects the expression of HADH mRNA
CTD PMID:27225895 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of HADHA mRNA
squalestatin 1 affects the expression of HADHA mRNA
CTD PMID:27225895 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta affects expression EXP
ISO
squalestatin 1 affects the expression of HADHB mRNA CTD PMID:27225895 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of HAMP mRNA
squalestatin 1 affects the expression of HAMP mRNA
CTD PMID:27225895 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO
EXP
squalestatin 1 results in increased expression of HMGCR mRNA CTD PMID:27225895 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO
EXP
squalestatin 1 results in increased expression of HMGCS1 mRNA CTD PMID:27225895 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hrg histidine-rich glycoprotein decreases expression ISO
EXP
squalestatin 1 results in decreased expression of HRG mRNA CTD PMID:27225895 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO
EXP
squalestatin 1 results in increased expression of HSD17B7 mRNA CTD PMID:27225895 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression ISO
EXP
squalestatin 1 results in increased expression of HSDL2 mRNA CTD PMID:27225895 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO
EXP
squalestatin 1 results in increased expression of IDI1 mRNA CTD PMID:27225895 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Il1b interleukin 1 beta decreases expression EXP
ISO
squalestatin 1 results in decreased expression of IL1B mRNA CTD PMID:27225895 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il33 interleukin 33 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of IL33 mRNA CTD PMID:27225895 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of IQGAP3 mRNA CTD PMID:27225895 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956
JBrowse link
G Irx2 iroquois homeobox 2 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of IRX2 mRNA
squalestatin 1 results in decreased expression of IRX2 mRNA
CTD PMID:27225895 NCBI chr 1:30,660,960...30,666,378
Ensembl chr 1:30,660,960...30,666,378
JBrowse link
G Itgb6 integrin subunit beta 6 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of ITGB6 mRNA
squalestatin 1 results in decreased expression of ITGB6 mRNA
CTD PMID:27225895 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Kif18b kinesin family member 18B decreases expression EXP
ISO
squalestatin 1 results in decreased expression of KIF18B mRNA CTD PMID:27225895 NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO
EXP
squalestatin 1 results in decreased expression of KIF20A mRNA CTD PMID:27225895 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif20b kinesin family member 20B decreases expression EXP
ISO
squalestatin 1 results in decreased expression of KIF20B mRNA CTD PMID:27225895 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of KIF23 mRNA CTD PMID:27225895 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO
EXP
squalestatin 1 results in decreased expression of KIF2C mRNA CTD PMID:27225895 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kitlg KIT ligand decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of KITLG mRNA
squalestatin 1 affects the expression of KITL mRNA
CTD PMID:27225895 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klb klotho beta decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of KLB mRNA
squalestatin 1 results in increased expression of KLB mRNA
CTD PMID:27225895 NCBI chr14:42,899,050...42,950,788
Ensembl chr14:42,899,510...42,950,799
JBrowse link
G Kntc1 kinetochore associated 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of KNTC1 mRNA CTD PMID:27225895 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
JBrowse link
G Krt23 keratin 23 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of KRT23 mRNA
squalestatin 1 affects the expression of KRT23 mRNA
CTD PMID:27225895 NCBI chr10:84,434,675...84,450,722
Ensembl chr10:84,434,380...84,450,983
JBrowse link
G Lgals4 galectin 4 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of LGALS4 mRNA
squalestatin 1 affects the expression of LGALS4 mRNA
CTD PMID:27225895 NCBI chr 1:84,123,497...84,132,605
Ensembl chr 1:84,124,764...84,132,481
JBrowse link
G Lgi2 leucine-rich repeat LGI family, member 2 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of LGI2 mRNA
squalestatin 1 results in decreased expression of LGI2 mRNA
CTD PMID:27225895 NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of LPAR1 mRNA
squalestatin 1 results in increased expression of LPAR1 mRNA
CTD PMID:27225895 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lpin1 lipin 1 decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of LPIN1 mRNA
squalestatin 1 results in increased expression of LPIN1 mRNA
CTD PMID:27225895 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpl lipoprotein lipase decreases expression EXP
ISO
squalestatin 1 results in decreased expression of LPL mRNA CTD PMID:27225895 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of LRAT mRNA
squalestatin 1 results in increased expression of LRAT mRNA
CTD PMID:27225895 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Lrmda leucine rich melanocyte differentiation associated increases expression ISO
EXP
squalestatin 1 results in increased expression of LRMDA mRNA CTD PMID:27225895 NCBI chr15:1,223,098...2,284,764
Ensembl chr15:1,225,710...2,284,749
JBrowse link
G Lss lanosterol synthase increases expression ISO
EXP
squalestatin 1 results in increased expression of LSS mRNA CTD PMID:27225895 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Ltb lymphotoxin beta increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of LTB mRNA
squalestatin 1 results in decreased expression of LTB mRNA
CTD PMID:27225895 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of LTBP2 mRNA
squalestatin 1 affects the expression of LTBP2 mRNA
CTD PMID:27225895 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Ly86 lymphocyte antigen 86 increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of LY86 mRNA
squalestatin 1 results in decreased expression of LY86 mRNA
CTD PMID:27225895 NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260
JBrowse link
G Mapt microtubule-associated protein tau decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of MAPT mRNA
squalestatin 1 results in increased expression of MAPT mRNA
CTD PMID:27225895 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like decreases expression ISO
EXP
squalestatin 1 results in decreased expression of MASTL mRNA CTD PMID:27225895 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Meiob meiosis specific with OB-fold increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of MEIOB mRNA
squalestatin 1 affects the expression of MEIOB mRNA
CTD PMID:27225895 NCBI chr10:13,833,170...13,865,684
Ensembl chr10:13,833,750...13,865,046
JBrowse link
G Melk maternal embryonic leucine zipper kinase decreases expression EXP
ISO
squalestatin 1 results in decreased expression of MELK mRNA CTD PMID:27225895 NCBI chr 5:58,540,393...58,600,937
Ensembl chr 5:58,540,449...58,600,937
JBrowse link
G Mgll monoglyceride lipase increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of MGLL mRNA
squalestatin 1 affects the expression of MGLL mRNA
CTD PMID:27225895 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Miox myo-inositol oxygenase increases expression ISO
EXP
squalestatin 1 results in increased expression of MIOX mRNA CTD PMID:27225895 NCBI chr 7:120,405,031...120,407,529
Ensembl chr 7:120,405,031...120,407,537
JBrowse link
G Mis18a MIS18 kinetochore protein A decreases expression ISO
EXP
squalestatin 1 results in decreased expression of MIS18A mRNA CTD PMID:27225895 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of MLYCD mRNA
squalestatin 1 affects the expression of MLYCD mRNA
CTD PMID:27225895 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Mme membrane metallo-endopeptidase increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of MME mRNA
squalestatin 1 results in decreased expression of MME mRNA
CTD PMID:27225895 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mss51 MSS51 mitochondrial translational activator decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of MSS51 mRNA
squalestatin 1 affects the expression of MSS51 mRNA
CTD PMID:27225895 NCBI chr15:3,805,240...3,819,385
Ensembl chr15:3,807,516...3,819,385
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression ISO
EXP
squalestatin 1 results in increased expression of MVD mRNA CTD PMID:27225895 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of MYBL2 mRNA
squalestatin 1 results in decreased expression of MYBL2 mRNA
CTD PMID:27225895 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO
EXP
squalestatin 1 results in decreased expression of NDC80 mRNA CTD PMID:27225895 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Neil3 nei-like DNA glycosylase 3 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of NEIL3 mRNA CTD PMID:27225895 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression ISO
EXP
squalestatin 1 results in increased expression of NFE2 mRNA CTD PMID:27225895 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of NNMT mRNA
squalestatin 1 affects the expression of NNMT mRNA
CTD PMID:27225895 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of NR0B2 mRNA CTD PMID:27225895 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression EXP
ISO
squalestatin 1 results in increased expression of NSDHL mRNA CTD PMID:27225895 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of NUSAP1 mRNA CTD PMID:27225895 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of OLR1 mRNA
squalestatin 1 affects the expression of OLR1 mRNA
CTD PMID:27225895 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of ORC1 mRNA CTD PMID:27225895 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G P2ry10b P2Y receptor family member 10B decreases expression ISO
EXP
squalestatin 1 results in decreased expression of P2RY10B mRNA CTD PMID:27225895 NCBI chr  X:72,255,526...72,281,013
Ensembl chr  X:72,238,713...72,281,012
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO
EXP
squalestatin 1 results in decreased expression of PBK mRNA CTD PMID:27225895 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO
EXP
squalestatin 1 results in decreased expression of PCLAF mRNA CTD PMID:27225895 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression EXP
ISO
squalestatin 1 results in increased expression of PCSK9 mRNA CTD PMID:27225895 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pctp phosphatidylcholine transfer protein increases expression EXP
ISO
squalestatin 1 results in increased expression of PCTP mRNA CTD PMID:27225895 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP
ISO
squalestatin 1 results in increased expression of PDK4 mRNA CTD PMID:27225895 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression EXP
ISO
squalestatin 1 results in decreased expression of PEMT mRNA CTD PMID:27225895 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of PEX11A mRNA
squalestatin 1 affects the expression of PEX11A mRNA
CTD PMID:27225895 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of PLA2R1 mRNA
squalestatin 1 results in decreased expression of PLA2R1 mRNA
CTD PMID:27225895 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660
JBrowse link
G Plekhs1 pleckstrin homology domain containing S1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of PLEKHS1 mRNA CTD PMID:27225895 NCBI chr 1:255,495,634...255,525,353
Ensembl chr 1:255,495,634...255,525,353
JBrowse link
G Plk1 polo-like kinase 1 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of PLK1 mRNA CTD PMID:27225895 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of PLPPR1 mRNA CTD PMID:27225895 NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
JBrowse link
G Pmvk phosphomevalonate kinase increases expression ISO
EXP
squalestatin 1 results in increased expression of PMVK mRNA CTD PMID:27225895 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of PNPLA7 mRNA
squalestatin 1 results in decreased expression of PNPLA7 mRNA
CTD PMID:27225895 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit decreases expression ISO
EXP
squalestatin 1 results in decreased expression of POLE2 mRNA CTD PMID:27225895 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO
EXP
squalestatin 1 results in increased expression of POR mRNA CTD PMID:27225895 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of PRC1 mRNA CTD PMID:27225895 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prnd prion like protein doppel affects expression
decreases expression
EXP
ISO
squalestatin 1 affects the expression of PRND mRNA
squalestatin 1 results in decreased expression of PRND mRNA
CTD PMID:27225895 NCBI chr 3:119,213,402...119,218,742
Ensembl chr 3:119,213,429...119,218,745
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of PTPRN mRNA
squalestatin 1 affects the expression of PTPRN mRNA
CTD PMID:27225895 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of RACGAP1 mRNA CTD PMID:27225895 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad54l RAD54 like decreases expression EXP
ISO
squalestatin 1 results in decreased expression of RAD54L mRNA CTD PMID:27225895 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rdh11 retinol dehydrogenase 11 increases expression ISO
EXP
squalestatin 1 results in increased expression of RDH11 mRNA CTD PMID:27225895 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
JBrowse link
G Reep1 receptor accessory protein 1 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of REEP1 mRNA
squalestatin 1 results in decreased expression of REEP1 mRNA
CTD PMID:27225895 NCBI chr 4:103,746,004...103,862,347
Ensembl chr 4:103,745,633...103,862,338
JBrowse link
G Retsat retinol saturase increases expression ISO
EXP
squalestatin 1 results in increased expression of RETSAT mRNA CTD PMID:27225895 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of RGMA mRNA
squalestatin 1 results in increased expression of RGMA mRNA
CTD PMID:27225895 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918
JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of RGS16 mRNA CTD PMID:27225895 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rhoa ras homolog family member A increases activity EXP squalestatin 1 results in increased activity of RHOA protein CTD PMID:20578043 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rnf186 ring finger protein 186 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of RNF186 mRNA
squalestatin 1 results in increased expression of RNF186 mRNA
CTD PMID:27225895 NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716
JBrowse link
G Rragd Ras-related GTP binding D increases expression ISO
EXP
squalestatin 1 results in increased expression of RRAGD mRNA CTD PMID:27225895 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
JBrowse link
G S100a4 S100 calcium-binding protein A4 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of S100A4 mRNA
squalestatin 1 results in decreased expression of S100A4 mRNA
CTD PMID:27225895 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100g S100 calcium binding protein G increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of S100G mRNA
squalestatin 1 results in decreased expression of S100G mRNA
CTD PMID:27225895 NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G Sapcd2 suppressor APC domain containing 2 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of SAPCD2 mRNA CTD PMID:27225895 NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of SAT2 mRNA
squalestatin 1 results in decreased expression of SAT2 mRNA
CTD PMID:27225895 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP squalestatin 1 results in increased expression of SCD mRNA CTD PMID:27225895 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO squalestatin 1 results in increased expression of SCD2 mRNA CTD PMID:27225895 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Sema3b semaphorin 3B increases expression ISO
EXP
squalestatin 1 results in increased expression of SEMA3B mRNA CTD PMID:27225895 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of SFRP1 mRNA
squalestatin 1 results in decreased expression of SFRP1 mRNA
CTD PMID:27225895 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sgo1 shugoshin 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of SGO1 mRNA CTD PMID:27225895 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of SHCBP1 mRNA CTD PMID:27225895 NCBI chr16:84,672,276...84,703,839
Ensembl chr16:84,672,321...84,703,844
JBrowse link
G Shisa4 shisa family member 4 increases expression ISO
EXP
squalestatin 1 results in increased expression of SHISA4 mRNA CTD PMID:27225895 NCBI chr13:46,800,487...46,803,703
Ensembl chr13:46,799,772...46,803,998
JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of SKA1 mRNA CTD PMID:27225895 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of SLC10A1 mRNA CTD PMID:27225895 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc13a3 solute carrier family 13 member 3 decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of SLC13A3 mRNA
squalestatin 1 results in increased expression of SLC13A3 mRNA
CTD PMID:27225895 NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
JBrowse link
G Slc15a3 solute carrier family 15 member 3 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of SLC15A3 mRNA CTD PMID:27225895 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157
JBrowse link
G Slc16a5 solute carrier family 16 member 5 affects expression
decreases expression
EXP
ISO
squalestatin 1 affects the expression of SLC16A5 mRNA
squalestatin 1 results in decreased expression of SLC16A5 mRNA
CTD PMID:27225895 NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of SLC17A1 mRNA
squalestatin 1 affects the expression of SLC17A1 mRNA
CTD PMID:27225895 NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
JBrowse link
G Slc17a3 solute carrier family 17 member 3 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of SLC17A3 mRNA
squalestatin 1 results in decreased expression of SLC17A3 mRNA
CTD PMID:27225895 NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP
ISO
squalestatin 1 results in increased expression of SLC22A5 mRNA CTD PMID:27225895 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc23a1 solute carrier family 23 member 1 increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of SLC23A1 mRNA
squalestatin 1 affects the expression of SLC23A1 mRNA
CTD PMID:27225895 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression ISO
EXP
squalestatin 1 results in increased expression of SLC25A20 mRNA CTD PMID:27225895 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO
EXP
squalestatin 1 results in increased expression of SLC25A34 mRNA CTD PMID:27225895 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Slc25a42 solute carrier family 25, member 42 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of SLC25A42 mRNA
squalestatin 1 results in increased expression of SLC25A42 mRNA
CTD PMID:27225895 NCBI chr16:19,213,914...19,251,990
Ensembl chr16:19,213,950...19,237,025
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of SLC2A4 mRNA CTD PMID:27225895 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc34a2 solute carrier family 34 member 2 increases expression
decreases expression
EXP
ISO
squalestatin 1 results in increased expression of SLC34A2 mRNA
squalestatin 1 results in decreased expression of SLC34A2 mRNA
CTD PMID:27225895 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc9b2 solute carrier family 9 member B2 decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of SLC9B2 mRNA
squalestatin 1 affects the expression of SLC9B2 mRNA
CTD PMID:27225895 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
JBrowse link
G Slco1a5 solute carrier organic anion transporter family, member 1A5 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of SLCO1A5 mRNA
squalestatin 1 results in decreased expression of SLCO1A5 mRNA
CTD PMID:27225895 NCBI chr 4:175,172,390...175,254,598
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression EXP
ISO
squalestatin 1 results in increased expression of SLCO4A1 mRNA CTD PMID:27225895 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
JBrowse link
G Smim3 small integral membrane protein 3 affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of SMIM3 mRNA
squalestatin 1 results in decreased expression of SMIM3 mRNA
CTD PMID:27225895 NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of SPAG5 mRNA CTD PMID:27225895 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of SRD5A2 mRNA
squalestatin 1 results in increased expression of SRD5A2 mRNA
CTD PMID:27225895 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of ST8SIA3 mRNA CTD PMID:27225895 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 increases expression ISO
EXP
squalestatin 1 results in increased expression of STARD4 mRNA CTD PMID:27225895 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP squalestatin 1 results in decreased expression of SULT1A1 mRNA CTD PMID:27225895 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases expression
affects expression
EXP
ISO
squalestatin 1 results in increased expression of SULT1C2 mRNA
squalestatin 1 affects the expression of SULT1C2 mRNA
CTD PMID:27225895 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 increases expression ISO squalestatin 1 results in increased expression of SULT1E1 mRNA CTD PMID:27225895 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of SULT2A1 mRNA
squalestatin 1 results in increased expression of SULT2A1 mRNA
CTD PMID:27225895 NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Tent5c terminal nucleotidyltransferase 5C decreases expression EXP
ISO
squalestatin 1 results in decreased expression of TENT5C mRNA CTD PMID:27225895 NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
JBrowse link
G Tex12 testis expressed 12 decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of TEX12 mRNA
squalestatin 1 results in increased expression of TEX12 mRNA
CTD PMID:27225895 NCBI chr 8:50,908,161...50,913,205
Ensembl chr 8:50,909,052...50,913,217
JBrowse link
G Thbd thrombomodulin decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of THBD mRNA
squalestatin 1 affects the expression of THBD mRNA
CTD PMID:27225895 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Thrsp thyroid hormone responsive increases expression
decreases expression
ISO
EXP
squalestatin 1 results in increased expression of THRSP mRNA
squalestatin 1 results in decreased expression of THRSP mRNA
CTD PMID:27225895 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tlcd4 TLC domain containing 4 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of TLCD4 mRNA
squalestatin 1 results in increased expression of TLCD4 mRNA
CTD PMID:27225895 NCBI chr 2:209,284,873...209,360,156
Ensembl chr 2:209,289,732...209,341,353
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression ISO
EXP
squalestatin 1 results in increased expression of TM7SF2 mRNA CTD PMID:27225895 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
G Tmem119 transmembrane protein 119 decreases expression
increases expression
EXP
ISO
squalestatin 1 results in decreased expression of TMEM119 mRNA
squalestatin 1 results in increased expression of TMEM119 mRNA
CTD PMID:27225895 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689
JBrowse link
G Tmem139 transmembrane protein 139 affects expression
increases expression
ISO
EXP
squalestatin 1 affects the expression of TMEM139 mRNA
squalestatin 1 results in increased expression of TMEM139 mRNA
CTD PMID:27225895 NCBI chr 4:71,147,072...71,149,151
Ensembl chr 4:71,146,724...71,167,399
JBrowse link
G Tmem164 transmembrane protein 164 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of TMEM164 mRNA CTD PMID:27225895 NCBI chr  X:106,288,019...106,448,642
Ensembl chr  X:106,289,371...106,448,640
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO
EXP
squalestatin 1 results in decreased expression of TNF mRNA CTD PMID:27225895 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf18 TNF superfamily member 18 decreases expression EXP
ISO
squalestatin 1 results in decreased expression of TNFSF18 mRNA CTD PMID:27225895 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression
affects expression
EXP
ISO
squalestatin 1 results in decreased expression of TNNT2 mRNA
squalestatin 1 affects the expression of TNNT2 mRNA
CTD PMID:27225895 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO
EXP
squalestatin 1 results in decreased expression of TOP2A mRNA CTD PMID:27225895 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tspan13 tetraspanin 13 increases expression ISO
EXP
squalestatin 1 results in increased expression of TSPAN13 mRNA CTD PMID:27225895 NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP
ISO
squalestatin 1 results in decreased expression of UBE2C mRNA CTD PMID:27225895 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP
ISO
squalestatin 1 results in increased expression of UCP2 mRNA CTD PMID:27225895 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of UGT2B1 mRNA
squalestatin 1 results in increased expression of UGT2B1 mRNA
CTD PMID:27225895 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO
EXP
squalestatin 1 results in decreased expression of UHRF1 mRNA CTD PMID:27225895 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
JBrowse link
G Uroc1 urocanate hydratase 1 affects expression ISO
EXP
squalestatin 1 affects the expression of UROC1 mRNA CTD PMID:27225895 NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591
JBrowse link
G Vnn1 vanin 1 decreases expression
increases expression
ISO
EXP
squalestatin 1 results in decreased expression of VNN1 mRNA
squalestatin 1 results in increased expression of VNN1 mRNA
CTD PMID:27225895 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A affects expression
decreases expression
ISO
EXP
squalestatin 1 affects the expression of ZC3H12A mRNA
squalestatin 1 results in decreased expression of ZC3H12A mRNA
CTD PMID:27225895 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19727
    role 19700
      biological role 19698
        biochemical role 19412
          enzyme inhibitor 18528
            EC 2.* (transferase) inhibitor 14626
              EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor 2482
                EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor 2482
                  EC 2.5.1.21 (squalene synthase) inhibitor 262
                    zaragozic acid A + 262
                    zaragozic acid C 0
paths to the root