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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chromogenic compound
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Accession:CHEBI:75050 term browser browse the term
Definition:Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates.
Synonyms:related_synonym: chromogen;   chromogenic compounds;   chromogens


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2-hydroxy-5-nitrophenyl hydrogen sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sts steroid sulfatase decreases activity ISO 4-nitrocatechol sulfate results in decreased activity of STS protein CTD PMID:6874424 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
4-methylumbelliferone beta-D-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO [UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO [UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 multiple interactions ISO [UGT1A8 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A8 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions ISO [UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO [UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr14:22,597,103...22,619,968 JBrowse link
4-methylumbelliferyl beta-D-galactoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca12 carbonic anhydrase 12 decreases activity ISO 4-methylumbelliferyl-galactopyranoside analog results in decreased activity of CA12 protein CTD PMID:22077347 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Ca9 carbonic anhydrase 9 decreases activity ISO 4-methylumbelliferyl-galactopyranoside analog results in decreased activity of CA9 protein CTD PMID:22077347 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
4-methylumbelliferyl beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gaa alpha glucosidase multiple interactions
increases metabolic processing
ISO GAA gene SNP inhibits the reaction [GAA protein results in increased metabolism of 4-methylumbelliferyl glucoside] CTD PMID:21963784 NCBI chr10:108,395,873...108,412,999
Ensembl chr10:108,395,860...108,413,059
JBrowse link
4-nitrophenyl beta-D-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO 4-nitrophenylglucuronide inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate] CTD PMID:11856762 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
4-nitrophenyl beta-D-xyloside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP 4-nitrophenyl beta-D-xyloside inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Pde4a phosphodiesterase 4A multiple interactions EXP 4-nitrophenyl beta-D-xyloside inhibits the reaction [FSHB protein results in increased activity of PDE4A protein] CTD PMID:17261351 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748
JBrowse link
glycyl-L-phenylalanine 2-naphthylamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 multiple interactions ISO 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
keto-phenylpyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid] CTD PMID:24709313 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO phenylpyruvic acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid] CTD PMID:22981274 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link

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  CHEBI ontology 19771
    role 19716
      application 19406
        indicator 8675
          visual indicator 4335
            colour indicator 4335
              one-colour indicator 16
                chromogenic compound 16
                  1-naphthyl N-acetyl-beta-D-glucosaminide 0
                  2-hydroxy-5-nitrophenyl hydrogen sulfate 1
                  2-naphthol AS BI-beta-D-glucuronide 0
                  2-naphthyl alpha-D-glucoside 0
                  2-naphthyl alpha-L-fucoside 0
                  2-naphthyl beta-D-galactoside 0
                  2-naphthyl beta-D-glucoside 0
                  2-naphthyl beta-L-fucoside 0
                  2-naphthyl butyrate 0
                  2-naphthyl dihydrogen phosphate 0
                  2-naphthyl octanoate 0
                  2-naphthyl tetradecanoate 0
                  2-nitrophenyl N-acetyl-alpha-D-glucosaminide 0
                  2-nitrophenyl N-acetyl-beta-D-glucosaminide 0
                  2-nitrophenyl beta-D-galactoside 0
                  2-nitrophenyl beta-D-glucoside 6-phosphate 0
                  3-(p-nitrophenyl)propanoic acid 0
                  4-(dimethylamino)benzaldehyde 0
                  4-methylumbelliferone beta-D-glucuronide 6
                  4-methylumbelliferyl alpha-D-galactoside 0
                  4-methylumbelliferyl alpha-L-arabinoside 0
                  4-methylumbelliferyl beta-D-galactoside 2
                  4-methylumbelliferyl beta-D-glucoside 1
                  4-methylumbelliferyl butyate 0
                  4-nitrophenyl 6-O-phosphono-beta-D-galactoside 0
                  4-nitrophenyl N-acetyl-alpha-D-glucosaminide 0
                  4-nitrophenyl N-acetyl-beta-D-glucosaminide 0
                  4-nitrophenyl alpha-D-glucoside 0
                  4-nitrophenyl alpha-D-xyloside 0
                  4-nitrophenyl alpha-L-arabinoside 0
                  4-nitrophenyl alpha-L-fucoside 0
                  4-nitrophenyl beta-D-glucoside 0
                  4-nitrophenyl beta-D-glucuronide 1
                  4-nitrophenyl beta-D-xyloside 2
                  4-nitrophenyl beta-L-fucoside 0
                  4-nitrophenyl beta-lactoside 0
                  5-bromo-3-hydroxyindole 0
                  5-bromo-3-indolyl decanoate 0
                  5-bromo-4-chloro-3-hydroxyindole 0
                  5-bromo-4-chloro-3-indolyl N-acetyl-beta-D-glucosaminide 0
                  5-bromo-4-chloro-3-indolyl acetate 0
                  5-bromo-4-chloro-3-indolyl alpha-D-mannoside 0
                  5-bromo-4-chloro-3-indolyl beta-D-galactoside 0
                  5-bromo-4-chloro-3-indolyl beta-D-glucoside 0
                  5-bromo-4-chloro-3-indolyl beta-D-glucuronide 0
                  5-bromo-4-chloro-3-indolyl phosphate 0
                  5-bromo-4-chloro-3-indolyl thymidine 3'-phosphate 0
                  5-oxo-L-proline 2-naphthylamide 0
                  6-bromo-2-naphthyl alpha-D-galactoside 0
                  6-bromo-2-naphthyl beta-D-galactoside 0
                  6-bromo-2-naphthyl beta-D-glucoside 0
                  6-bromo-2-naphthyl beta-D-mannoside 0
                  DL-methionine 2-naphthylamide 0
                  L-alanine 2-naphthylamide 0
                  L-alanyl-L-alanine 2-naphthylamide 0
                  L-alanyl-L-phenylalanyl-L-proline 2-naphthylamide 0
                  L-arginine 2-naphthylamide 0
                  L-asparagine 2-naphthylamide 0
                  L-cysteine 2-naphthylamide 0
                  L-cystine di-2-naphthylamide 0
                  L-glutamine 2-naphthylamide 0
                  L-glutamyl-L-glutamic acid 2-naphthylamide 0
                  L-glutamylglycine 2-naphthylamide 0
                  L-glutamylglycyl-L-arginine 2-naphthylamide 0
                  L-histidine 2-naphthylamide 0
                  L-hydroxyproline 2-naphthylamide 0
                  L-isoleucine 2-naphthylamide 0
                  L-leucine 2-naphthylamide 0
                  L-leucine 4-methoxy-2-naphthylamide 0
                  L-leucylglycine 2-naphthylamide 0
                  L-lysine 2-naphthylamide 0
                  L-ornithine 2-naphthylamide 0
                  L-phenylalanine 2-naphthylamide 0
                  L-proline 2-naphthylamide 0
                  L-serine 2-naphthylamide 0
                  L-seryl-L-tyrosine 2-naphthylamide 0
                  L-threonine 2-naphthylamide 0
                  L-tryptophan 2-naphthylamide 0
                  L-tyrosine 2-naphthylamide 0
                  L-valine 2-naphthylamide 0
                  N-(alpha-L-aspartyl)-2-naphthylamine 0
                  N-(alpha-L-glutamyl)-2-naphthylamine 0
                  N-(gamma-L-glutamyl)-2-naphthylamine 0
                  N-benzoyl-D-arginine 2-naphthylamide + 0
                  N-benzoyl-D-phenylalanine 2-naphthylamide + 0
                  N-benzoyl-DL-arginine 2-naphthylamide 0
                  N-benzoyl-DL-phenylalanine 2-naphthylamide 0
                  N-benzoyl-L-arginine 2-naphthylamide + 0
                  N-benzoyl-L-leucine 2-naphthylamide 0
                  N-benzoyl-L-phenylalanine 2-naphthylamide + 0
                  N-benzoyl-L-valylglycine 4-methoxy-2-naphthylamide 0
                  N-carbobenzyloxy-glycylglycyl-L-arginine 2-naphthylamide 0
                  N-glutaryl-L-phenylalanine 2-naphthylamide 0
                  beta-alanine 2-naphthylamide 0
                  bis(p-nitrophenyl)phosphocholine 0
                  ethyl N-benzoyl-L-tyrosinate 0
                  glycine 2-naphthylamide 0
                  glycyl-L-phenylalanine 2-naphthylamide 1
                  glycyl-L-proline 2-naphthylamide 0
                  glycyl-L-tryptophan 2-naphthylamide 0
                  glycylglycine 2-naphthylamide 0
                  keto-phenylpyruvate 0
                  keto-phenylpyruvic acid + 2
                  p-nitrophenyl phenyl phosphonate 0
                  phenyl hydrogen phosphonate 0
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