nefazodone - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	nefazodone	go back to main search page
Accession:	CHEBI:7494	browse the term
Definition:	A N-alkylpiperazine that has formula C25H32ClN5O2.
Synonyms:	exact_synonym:	2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
	related_synonym:	1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one; Formula=C25H32ClN5O2; InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3; InChIKey=VRBKIVRKKCLPHA-UHFFFAOYSA-N; SMILES=CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1; nefazodona; nefazodonum
	xref:	Beilstein:4728403; CAS:83366-66-9; DrugBank:DB01149; Drug_Central:1890; KEGG:C07256; KEGG:D08257; LINCS:LSM-4031
	xref_mesh:	MESH:C051752
	xref:	Patent:US4338317; Wikipedia:Nefazodone

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Genes (1773)

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

APOBEC1 complementation factor

increases expression

EXP

nefazodone results in increased expression of A1CF mRNA

NCBI chr 1:229,736,037...229,823,499
Ensembl chr 1:239,149,493...239,236,817

G

arylacetamide deacetylase

decreases expression

EXP

nefazodone results in decreased expression of AADAC mRNA

NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525

G

aminoadipate aminotransferase

decreases expression

EXP

nefazodone results in decreased expression of AADAT mRNA

NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540

G

angio-associated, migratory cell protein

increases expression

EXP

nefazodone results in increased expression of AAMP mRNA

NCBI chr 9:83,312,519...83,318,325
Ensembl chr 9:83,312,519...83,318,325

G

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

increases expression

EXP

nefazodone results in increased expression of AASDHPPT mRNA

NCBI chr 8:9,731,592...9,748,934
Ensembl chr 8:9,738,172...9,748,953

G

4-aminobutyrate aminotransferase

decreases expression

EXP

nefazodone results in decreased expression of ABAT mRNA

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474

G

ATP binding cassette subfamily A member 3

decreases expression

EXP

nefazodone results in decreased expression of ABCA3 mRNA

NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285

G

ATP-binding cassette, subfamily A (ABC1), member 8a

decreases expression

EXP

nefazodone results in decreased expression of ABCA8A mRNA

NCBI chr10:95,002,334...95,072,315
Ensembl chr10:95,501,798...95,571,873

G

ATP binding cassette subfamily B member 11

multiple interactions
decreases activity
decreases expression

ISO
EXP

nefazodone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
nefazodone results in decreased activity of ABCB11 protein
nefazodone results in decreased expression of ABCB11 mRNA

PMID:16410371 PMID:20829430 PMID:22646477 PMID:23956101 PMID:24014644 More...

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581

G

ATP binding cassette subfamily B member 4

increases expression
decreases activity
multiple interactions

EXP
ISO

nefazodone results in increased expression of ABCB4 mRNA
nefazodone results in decreased activity of ABCB4 protein
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ABCB4 mRNA

PMID:24136188 PMID:28437613 PMID:33819548

NCBI chr 4:26,106,895...26,164,440

G

ATP binding cassette subfamily B member 6

increases expression

EXP

nefazodone results in increased expression of ABCB6 mRNA

NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526

G

ATP binding cassette subfamily C member 3

increases expression
multiple interactions
decreases expression

EXP
ISO

nefazodone results in increased expression of ABCC3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of ABCC3 mRNA
nefazodone results in decreased expression of ABCC3 mRNA

PMID:24136188 PMID:32152650

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494

G

ATP binding cassette subfamily C member 4

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ABCC4 mRNA
nefazodone results in increased expression of ABCC4 mRNA

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily C member 6

decreases expression

EXP

nefazodone results in decreased expression of ABCC6 mRNA

NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895

G

ATP binding cassette subfamily E member 1

increases expression

EXP

nefazodone results in increased expression of ABCE1 mRNA

NCBI chr19:45,109,880...45,134,819
Ensembl chr19:45,109,906...45,134,819

G

ATP binding cassette subfamily F member 3

increases expression

EXP

nefazodone results in increased expression of ABCF3 mRNA

NCBI chr11:93,844,863...93,856,595
Ensembl chr11:93,844,363...93,856,595

G

ATP binding cassette subfamily G member 2

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ABCG2 mRNA

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

ATP-binding cassette, subfamily G (WHITE), member 3-like 2

decreases expression

EXP

nefazodone results in decreased expression of ABCG3L2 mRNA

NCBI chr14:4,493,259...4,538,264
Ensembl chr14:4,798,053...4,838,117

G

ATP binding cassette subfamily G member 5

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of ABCG5 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ABCG5 mRNA

PMID:24136188 PMID:33819548

NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376

G

ATP binding cassette subfamily G member 8

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of ABCG8 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ABCG8 mRNA

PMID:24136188 PMID:33819548

NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730

G

abhydrolase domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of ABHD1 mRNA

NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464

G

abhydrolase domain containing 2, acylglycerol lipase

decreases expression

EXP

nefazodone results in decreased expression of ABHD2 mRNA

NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

EXP

nefazodone results in increased expression of ABHD4 mRNA

NCBI chr15:31,674,090...31,686,051
Ensembl chr15:31,674,143...31,687,007

G

actin binding LIM protein family, member 3

increases expression

EXP

nefazodone results in increased expression of ABLIM3 mRNA

NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710

G

ankyrin repeat and BTB domain containing 1

increases expression

EXP

nefazodone results in increased expression of ABTB1 mRNA

NCBI chr 4:121,299,302...121,305,667
Ensembl chr 4:122,856,564...122,862,789

G

acetyl-CoA acyltransferase 1A

increases expression

EXP

nefazodone results in increased expression of ACAA1 mRNA

NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241

G

acetyl-CoA acyltransferase 2

increases expression

EXP

nefazodone results in increased expression of ACAA2 mRNA

NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420

G

acetyl-CoA carboxylase alpha

decreases expression

EXP

nefazodone results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acyl-CoA dehydrogenase family, member 11

increases expression

EXP

nefazodone results in increased expression of ACAD11 mRNA

NCBI chr 8:113,560,142...113,625,346
Ensembl chr 8:113,560,196...113,625,352

G

ATP citrate lyase

decreases expression

EXP

nefazodone results in decreased expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631

G

aconitase 1

increases expression

EXP

nefazodone results in increased expression of ACO1 mRNA

NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600

G

aconitase 2

increases expression

EXP

nefazodone results in increased expression of ACO2 mRNA

NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892

G

acyl-CoA thioesterase 12

increases expression

EXP

nefazodone results in increased expression of ACOT12 mRNA

NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298

G

acyl-CoA thioesterase 13

decreases expression

EXP

nefazodone results in decreased expression of ACOT13 mRNA

NCBI chr17:40,668,404...40,680,876
Ensembl chr17:40,668,316...40,680,876

G

acyl-CoA thioesterase 2

increases expression

EXP

nefazodone results in increased expression of ACOT2 mRNA

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502

G

acyl-CoA thioesterase 7

increases expression

EXP

nefazodone results in increased expression of ACOT7 mRNA

NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033

G

acyl-CoA thioesterase 8

increases expression

EXP

nefazodone results in increased expression of ACOT8 mRNA

NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:173,950,531...173,962,570

G

acyl-CoA oxidase 1

increases expression

EXP

nefazodone results in increased expression of ACOX1 mRNA

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136

G

acyl-CoA oxidase 3, pristanoyl

decreases expression

EXP

nefazodone results in decreased expression of ACOX3 mRNA

NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881

G

acid phosphatase 1

increases expression

EXP

nefazodone results in increased expression of ACP1 mRNA

NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959

G

acid phosphatase 2, lysosomal

decreases expression

EXP

nefazodone results in decreased expression of ACP2 mRNA

NCBI chr 3:97,630,654...97,642,601
Ensembl chr 3:97,631,326...97,642,565

G

acyl-CoA synthetase family member 2

decreases expression

EXP

nefazodone results in decreased expression of ACSF2 mRNA

NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050

G

acyl-CoA synthetase long-chain family member 1

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of ACSL1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ACSL1 mRNA

PMID:24136188 PMID:33819548

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023

G

acyl-CoA synthetase long-chain family member 4

increases expression

EXP

nefazodone results in increased expression of ACSL4 mRNA

NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261

G

acyl-CoA synthetase long-chain family member 5

decreases expression

EXP

nefazodone results in decreased expression of ACSL5 mRNA

NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943

G

acyl-CoA synthetase medium-chain family member 2

increases expression

EXP

nefazodone results in increased expression of ACSM2A mRNA

NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:183,347,705...183,386,453

G

acyl-CoA synthetase short-chain family member 2

decreases expression

EXP

nefazodone results in decreased expression of ACSS2 mRNA

NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830

G

actin related protein 3

increases expression

EXP

nefazodone results in increased expression of ACTR3 mRNA

NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

decreases expression

EXP

nefazodone results in decreased expression of ADAMTS7 mRNA

NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132

G

ArfGAP with dual PH domains 2

decreases expression

EXP

nefazodone results in decreased expression of ADAP2 mRNA

NCBI chr10:65,635,891...65,665,019
Ensembl chr10:65,622,434...65,664,022

G

aarF domain containing kinase 5

increases expression

EXP

nefazodone results in increased expression of ADCK5 mRNA

NCBI chr 7:110,182,275...110,200,088
Ensembl chr 7:110,181,981...110,200,088

G

adducin 1

increases expression

EXP

nefazodone results in increased expression of ADD1 mRNA

NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732

G

adhesion G protein-coupled receptor G1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ADGRG1 mRNA

NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,010,031...10,047,124

G

adhesion G protein-coupled receptor L2

decreases expression

EXP

nefazodone results in decreased expression of ADGRL2 mRNA

NCBI chr 2:240,356,176...240,987,246
Ensembl chr 2:240,356,177...240,855,933

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH1C mRNA

NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291

G

alcohol dehydrogenase 4 (class II), pi polypeptide

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of ADH4 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH4 mRNA

PMID:24136188 PMID:33819548

NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879

G

alcohol dehydrogenase 6 (class V)

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH6 mRNA

NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914

G

alcohol dehydrogenase, iron containing, 1

decreases expression

EXP

nefazodone results in decreased expression of ADHFE1 mRNA

NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835

G

ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent

increases expression

EXP

nefazodone results in increased expression of ADPRM mRNA

NCBI chr10:51,732,073...51,744,635
Ensembl chr10:52,230,233...52,243,569

G

ADP-ribosylserine hydrolase

increases expression

EXP

nefazodone results in increased expression of ADPRS mRNA

NCBI chr 5:143,898,542...143,903,816
Ensembl chr 5:143,898,542...143,903,816

G

adrenoceptor alpha 1B

decreases expression

EXP

nefazodone results in decreased expression of ADRA1B mRNA

NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

EXP

nefazodone results in increased expression of ADRM1 mRNA

NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483

G

adenylosuccinate lyase

increases expression

EXP

nefazodone results in increased expression of ADSL mRNA

NCBI chr 7:114,359,440...114,383,618
Ensembl chr 7:114,359,440...114,384,872

G

AFG3 like matrix AAA peptidase subunit 2

increases expression

EXP

nefazodone results in increased expression of AFG3L2 mRNA

NCBI chr18:63,224,163...63,269,000
Ensembl chr18:63,224,163...63,269,000

G

afamin

decreases expression

EXP

nefazodone results in decreased expression of AFM mRNA

NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039

G

alanine-glyoxylate aminotransferase 2

decreases expression

EXP

nefazodone results in decreased expression of AGXT2 mRNA

NCBI chr 2:61,063,416...61,104,828
Ensembl chr 2:61,063,419...61,105,090

G

adenosylhomocysteinase-like 1

increases expression

EXP

nefazodone results in increased expression of AHCYL1 mRNA

NCBI chr 2:197,982,335...198,016,770
Ensembl chr 2:197,982,344...198,033,930

G

activator of Hsp90 ATPase activity 1

increases expression

EXP

nefazodone results in increased expression of AHSA1 mRNA

NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595

G

androgen-induced 1

increases expression

EXP

nefazodone results in increased expression of AIG1 mRNA

NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

EXP

nefazodone results in increased expression of AIMP1 mRNA

NCBI chr 2:223,825,930...223,849,477
Ensembl chr 2:223,825,931...223,849,994

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

EXP

nefazodone results in increased expression of AIMP2 mRNA

NCBI chr12:15,814,854...15,824,432
Ensembl chr12:15,814,878...15,824,431

G

aryl-hydrocarbon receptor-interacting protein

increases expression

EXP

nefazodone results in increased expression of AIP mRNA

NCBI chr 1:210,837,473...210,848,691
Ensembl chr 1:210,836,755...210,848,634

G

adenylate kinase 3

increases expression

EXP

nefazodone results in increased expression of AK3 mRNA

NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183

G

adenylate kinase 4

decreases expression

EXP

nefazodone results in decreased expression of AK4 mRNA

NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401

G

A-kinase anchoring protein 8 like

decreases expression

EXP

nefazodone results in decreased expression of AKAP8L mRNA

NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811

G

aldo-keto reductase family 1 member A1

increases expression

EXP

nefazodone results in increased expression of AKR1A1 mRNA

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035

G

aldo-keto reductase family 1, member C1

decreases expression

EXP

nefazodone results in decreased expression of AKR1C1 mRNA

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247

G

aldo-keto reductase family 1, member C14

increases expression

EXP

nefazodone results in increased expression of AKR1C14 mRNA

NCBI chr17:71,066,197...71,083,184
Ensembl chr17:71,066,200...71,083,157

G

aldo-keto reductase family 1, member D1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of AKR1D1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of AKR1D1 mRNA

PMID:24136188 PMID:33819548

NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540

G

aldo-keto reductase family 7, member A2

increases expression

EXP

nefazodone results in increased expression of AKR7A2 mRNA

NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109

G

aldo-keto reductase family 7 member A3

increases expression
decreases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of AKR7A3 mRNA
nefazodone results in decreased expression of AKR7A3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A3 mRNA

PMID:24136188 PMID:32152650

NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153

G

AKT1 substrate 1

increases expression

EXP

nefazodone results in increased expression of AKT1S1 mRNA

NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:104,469,803...104,476,167

G

5'-aminolevulinate synthase 1

increases expression

EXP

nefazodone results in increased expression of ALAS1 mRNA

NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642

G

albumin

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ALB mRNA

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldehyde dehydrogenase 1 family, member A1

increases expression

EXP

nefazodone results in increased expression of ALDH1A1 mRNA

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500

G

aldehyde dehydrogenase family 1, subfamily A7

increases expression

EXP

nefazodone results in increased expression of ALDH1A7 mRNA

NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523

G

aldehyde dehydrogenase 1 family, member B1

decreases expression

EXP

nefazodone results in decreased expression of ALDH1B1 mRNA

NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365

G

aldehyde dehydrogenase 1 family, member L1

increases expression

EXP

nefazodone results in increased expression of ALDH1L1 mRNA

NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704

G

aldehyde dehydrogenase 3 family, member A2

increases expression

EXP

nefazodone results in increased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648

G

aldolase, fructose-bisphosphate A

increases expression

EXP

nefazodone results in increased expression of ALDOA mRNA

NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211

G

ALG12, alpha-1,6-mannosyltransferase

increases expression

EXP

nefazodone results in increased expression of ALG12 mRNA

NCBI chr 7:121,774,796...121,789,175
Ensembl chr 7:121,768,234...121,788,983

G

ALG3, alpha-1,3- mannosyltransferase

increases expression

EXP

nefazodone results in increased expression of ALG3 mRNA

NCBI chr11:80,300,487...80,306,014
Ensembl chr11:93,804,891...93,812,060

G

alkB homolog 7

increases expression

EXP

nefazodone results in increased expression of ALKBH7 mRNA

NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048

G

alkaline phosphatase, placental

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ALPP mRNA

NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451

G

adenosylmethionine decarboxylase 1

increases expression

EXP

nefazodone results in increased expression of AMD1 mRNA

NCBI chr20:45,250,289...45,324,939
Ensembl chr20:45,250,289...45,265,982

G

AMMECR1 like

decreases expression

EXP

nefazodone results in decreased expression of AMMECR1L mRNA

NCBI chr18:23,661,649...23,685,391
Ensembl chr18:23,661,341...23,685,649

G

adenosine monophosphate deaminase 3

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of AMPD3 mRNA

NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608

G

aminomethyltransferase

increases expression

EXP

nefazodone results in increased expression of AMT mRNA

NCBI chr 8:117,859,700...117,866,692
Ensembl chr 8:117,860,345...117,866,803

G

amylase alpha 1

decreases expression

EXP

nefazodone results in decreased expression of AMY1A mRNA

NCBI chr 2:204,071,101...204,085,910
Ensembl chr 2:204,071,098...204,086,239

G

angiogenin

decreases expression

EXP

nefazodone results in decreased expression of ANG mRNA

NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106

G

angiopoietin-like 3

decreases expression

EXP

nefazodone results in decreased expression of ANGPTL3 mRNA

NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444

G

angiopoietin-like 4

decreases expression

EXP

nefazodone results in decreased expression of ANGPTL4 mRNA

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

EXP

nefazodone results in decreased expression of ANKH mRNA

NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699

G

ankyrin repeat domain 13C

decreases expression

EXP

nefazodone results in decreased expression of ANKRD13C mRNA

NCBI chr 2:249,679,752...249,729,272
Ensembl chr 2:249,681,872...249,729,272

G

ankyrin repeat and sterile alpha motif domain containing 4B

decreases expression

EXP

nefazodone results in decreased expression of ANKS4B mRNA

NCBI chr 1:183,934,528...183,989,127
Ensembl chr 1:183,978,769...183,989,122

G

anoctamin 10

increases expression

EXP

nefazodone results in increased expression of ANO10 mRNA

NCBI chr 8:130,719,177...130,838,243
Ensembl chr 8:130,718,755...130,877,636

G

acidic nuclear phosphoprotein 32 family member A

decreases expression

EXP

nefazodone results in decreased expression of ANP32A mRNA

NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922

G

acidic nuclear phosphoprotein 32 family member B

increases expression

EXP

nefazodone results in increased expression of ANP32B mRNA

NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437

G

acidic nuclear phosphoprotein 32 family member E

increases expression

EXP

nefazodone results in increased expression of ANP32E mRNA

NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986

G

alanyl aminopeptidase, membrane

decreases expression

EXP

nefazodone results in decreased expression of ANPEP mRNA

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

ANTXR cell adhesion molecule 2

decreases expression

EXP

nefazodone results in decreased expression of ANTXR2 mRNA

NCBI chr14:11,845,774...11,986,166
Ensembl chr14:11,845,700...11,986,168

G

annexin A3

decreases expression

EXP

nefazodone results in decreased expression of ANXA3 mRNA

NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849

G

annexin A5

decreases expression

EXP

nefazodone results in decreased expression of ANXA5 mRNA

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

annexin A7

increases expression

EXP

nefazodone results in increased expression of ANXA7 mRNA

NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891

G

aldehyde oxidase 1

increases expression
decreases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of AOX1 mRNA
nefazodone results in decreased expression of AOX1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AOX1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980

G

adaptor related protein complex 1 subunit mu 1

increases expression

EXP

nefazodone results in increased expression of AP1M1 mRNA

NCBI chr16:17,620,910...17,636,431
Ensembl chr16:17,616,187...17,636,462

G

adaptor related protein complex 2 subunit mu 1

increases expression

EXP

nefazodone results in increased expression of AP2M1 mRNA

NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

EXP

nefazodone results in increased expression of APEX1 mRNA

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

apoptosis inhibitor 5

increases expression

EXP

nefazodone results in increased expression of API5 mRNA

NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580

G

amyloid beta precursor like protein 2

decreases expression

EXP

nefazodone results in decreased expression of APLP2 mRNA

NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031

G

adipocyte plasma membrane associated protein

decreases expression

EXP

nefazodone results in decreased expression of APMAP mRNA

NCBI chr 3:159,869,451...159,897,727
Ensembl chr 3:159,869,451...159,897,726

G

apolipoprotein A1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of APOA1 mRNA

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729

G

apolipoprotein A4

decreases expression

EXP

nefazodone results in decreased expression of APOA4 mRNA

NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164

G

apolipoprotein A5

decreases expression

EXP

nefazodone results in decreased expression of APOA5 mRNA

NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507

G

apolipoprotein L2

decreases expression

EXP

nefazodone results in decreased expression of APOL3 mRNA

NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:111,211,893...111,217,223

G

Apol9a-Apol7a readthrough

decreases expression

EXP

nefazodone results in decreased expression of APOL7B mRNA

NCBI chr 7:109,118,559...109,149,798
Ensembl chr 7:111,011,645...111,017,084

G

apolipoprotein M

decreases expression

EXP

nefazodone results in decreased expression of APOM mRNA

NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218

G

aquaporin 8

increases expression

EXP

nefazodone results in increased expression of AQP8 mRNA

NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242

G

archain 1

increases expression

EXP

nefazodone results in increased expression of ARCN1 mRNA

NCBI chr 8:53,954,401...53,979,005
Ensembl chr 8:53,954,404...53,979,005

G

ARF GTPase 1

increases expression

EXP

nefazodone results in increased expression of ARF1 mRNA

NCBI chr10:44,497,543...44,513,994

G

ARF GTPase 6

increases expression

EXP

nefazodone results in increased expression of ARF6 mRNA

NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:93,569,234...93,610,536

G

ARF interacting protein 2

decreases expression

EXP

nefazodone results in decreased expression of ARFIP2 mRNA

NCBI chr 1:169,387,484...169,392,290
Ensembl chr 1:169,387,485...169,392,166

G

arginase 1

increases expression

EXP

nefazodone results in increased expression of ARG1 mRNA

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

Rho guanine nucleotide exchange factor 19

decreases expression

EXP

nefazodone results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:158,818,932...158,837,196

G

AT-rich interaction domain 1A

decreases expression

EXP

nefazodone results in decreased expression of ARID1A mRNA

NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386

G

ARF like GTPase 4A

increases expression

EXP

nefazodone results in increased expression of ARL4A mRNA

NCBI chr 6:62,809,287...62,811,297
Ensembl chr 6:62,804,548...62,820,760

G

ARF like GTPase 5A

increases expression

EXP

nefazodone results in increased expression of ARL5A mRNA

NCBI chr 3:57,287,599...57,312,488
Ensembl chr 3:57,289,846...57,312,488

G

ARL6 interacting reticulophagy regulator 1

decreases expression

EXP

nefazodone results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232

G

ARF like GTPase 6 interacting protein 4

increases expression

EXP

nefazodone results in increased expression of ARL6IP4 mRNA

NCBI chr12:38,140,566...38,142,711
Ensembl chr12:38,140,550...38,142,724

G

actin related protein 2/3 complex, subunit 5-like

increases expression

EXP

nefazodone results in increased expression of ARPC5L mRNA

NCBI chr 3:43,169,518...43,177,224
Ensembl chr 3:43,169,462...43,177,240
Ensembl chr 9:43,169,462...43,177,240

G

actin-related protein 2/3 complex inhibitor

increases expression

EXP

nefazodone results in increased expression of ARPIN mRNA

NCBI chr 1:143,273,590...143,282,426
Ensembl chr 1:143,273,590...143,282,532

G

cAMP-regulated phosphoprotein 19

increases expression

EXP

nefazodone results in increased expression of ARPP19 mRNA

NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385
Ensembl chr 8:119,691,942...119,692,385

G

arylsulfatase A

decreases expression

EXP

nefazodone results in decreased expression of ARSA mRNA

NCBI chr 7:122,422,971...122,426,971
Ensembl chr 7:122,422,982...122,428,401

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

decreases expression

EXP

nefazodone results in decreased expression of ASAP2 mRNA

NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:46,386,605...46,549,669

G

anti-silencing function 1A histone chaperone

increases expression

EXP

nefazodone results in increased expression of ASF1A mRNA

NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639

G

ASH1 like histone lysine methyltransferase

decreases expression

EXP

nefazodone results in decreased expression of ASH1L mRNA

NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

EXP

nefazodone results in increased expression of ASNS mRNA

NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050

G

asparagine synthetase domain containing 1

increases expression

EXP

nefazodone results in increased expression of ASNSD1 mRNA

NCBI chr 9:55,618,799...55,631,064
Ensembl chr 9:55,618,799...55,631,064

G

asparaginase

decreases expression

EXP

nefazodone results in decreased expression of ASPG mRNA

NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417

G

activating transcription factor 1

increases expression

EXP

nefazodone results in increased expression of ATF1 mRNA

NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485

G

activating transcription factor 4

multiple interactions
increases expression

ISO

2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of ATF4 protein]; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF4 mRNA
nefazodone results in increased expression of ATF4 mRNA; nefazodone results in increased expression of ATF4 protein

PMID:27613715 PMID:32152650

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

activating transcription factor 5

increases expression

EXP

nefazodone results in increased expression of ATF5 mRNA

NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183

G

activating transcription factor 6

increases expression
multiple interactions

ISO

nefazodone results in increased expression of ATF6 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF6 mRNA

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033

G

autophagy related 7

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATG7 mRNA
nefazodone results in increased expression of ATG7 mRNA

NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319

G

autophagy related 9A

decreases expression

EXP

nefazodone results in decreased expression of ATG9A mRNA

NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:84,126,071...84,136,666

G

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

increases expression

EXP

nefazodone results in increased expression of ATIC mRNA

NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756

G

atlastin GTPase 2

increases expression

EXP

nefazodone results in increased expression of ATL2 mRNA

NCBI chr 6:20,891,220...20,932,644
Ensembl chr 6:20,891,227...20,933,320

G

atlastin GTPase 3

increases expression

EXP

nefazodone results in increased expression of ATL3 mRNA

NCBI chr 1:214,110,127...214,151,098
Ensembl chr 1:214,109,702...214,152,510

G

atonal bHLH transcription factor 8

decreases expression

EXP

nefazodone results in decreased expression of ATOH8 mRNA

NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379

G

atos homolog A

decreases expression

EXP

nefazodone results in decreased expression of ATOSA mRNA

NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091

G

ATPase phospholipid transporting 11A

decreases expression

EXP

nefazodone results in decreased expression of ATP11A mRNA

NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767

G

ATP synthase F1 subunit delta

increases expression

EXP

nefazodone results in increased expression of ATP5F1D mRNA

NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:10,211,262...10,216,583

G

ATP synthase inhibitory factor subunit 1

increases expression

EXP

nefazodone results in increased expression of ATP5IF1 mRNA

NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677

G

ATP synthase membrane subunit c locus 1

increases expression

EXP

nefazodone results in increased expression of ATP5MC1 mRNA

NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363

G

ATP synthase peripheral stalk subunit d

increases expression

EXP

nefazodone results in increased expression of ATP5PD mRNA

NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954

G

ATPase H+ transporting accessory protein 2

increases expression

EXP

nefazodone results in increased expression of ATP6AP2 mRNA

NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875

G

ATPase H+ transporting V0 subunit B

increases expression

EXP

nefazodone results in increased expression of ATP6V0B mRNA

NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828

G

ATPase H+ transporting V0 subunit e1

increases expression

EXP

nefazodone results in increased expression of ATP6V0E1 mRNA

NCBI chr10:16,984,084...17,007,156
Ensembl chr10:16,984,084...17,028,858

G

ATPase H+ transporting V1 subunit A

increases expression

EXP

nefazodone results in increased expression of ATP6V1A mRNA

NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603

G

ATPase H+ transporting V1 subunit B2

increases expression

EXP

nefazodone results in increased expression of ATP6V1B2 mRNA

NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839

G

ATPase H+ transporting V1 subunit C1

increases expression

EXP

nefazodone results in increased expression of ATP6V1C1 mRNA

NCBI chr 7:71,719,326...71,757,191
Ensembl chr 7:71,719,404...71,757,184

G

ATPase H+ transporting V1 subunit D

increases expression

EXP

nefazodone results in increased expression of ATP6V1D mRNA

NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346

G

ATPase H+ transporting V1 subunit E1

increases expression

EXP

nefazodone results in increased expression of ATP6V1E1 mRNA

NCBI chr 4:155,694,534...155,716,660
Ensembl chr 4:155,694,534...155,716,678

G

ATPase H+ transporting V1 subunit F

increases expression

EXP

nefazodone results in increased expression of ATP6V1F mRNA

NCBI chr 4:59,033,020...59,035,980

G

ATPase H+ transporting V1 subunit G1

increases expression

EXP

nefazodone results in increased expression of ATP6V1G1 mRNA

NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930

G

ATPase H+ transporting V1 subunit H

increases expression

EXP

nefazodone results in increased expression of ATP6V1H mRNA

NCBI chr 5:19,176,849...19,282,516
Ensembl chr 5:19,176,849...19,282,516

G

ATP synthase c subunit lysine N-methyltransferase

increases expression

EXP

nefazodone results in increased expression of ATPSCKMT mRNA

NCBI chr 2:84,313,991...84,329,195
Ensembl chr 2:84,313,921...84,329,194

G

ATR serine/threonine kinase

decreases expression

ISO

nefazodone results in decreased expression of ATR mRNA

NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718

G

attractin

decreases expression

EXP

nefazodone results in decreased expression of ATRN mRNA

NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360

G

AU RNA binding methylglutaconyl-CoA hydratase

increases expression

EXP

nefazodone results in increased expression of AUH mRNA

NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

EXP

nefazodone results in increased expression of AUP1 mRNA

NCBI chr 4:117,118,035...117,121,063
Ensembl chr 4:117,117,999...117,121,061

G

arginine vasopressin receptor 1A

decreases expression

EXP

nefazodone results in decreased expression of AVPR1A mRNA

NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837

G

5-azacytidine induced 2

increases expression

EXP

nefazodone results in increased expression of AZI2 mRNA

NCBI chr 8:126,651,268...126,674,795
Ensembl chr 8:126,651,206...126,676,182

G

antizyme inhibitor 1

increases expression

EXP

nefazodone results in increased expression of AZIN1 mRNA

NCBI chr 7:71,539,711...71,566,515
Ensembl chr 7:71,539,711...71,566,515

G

beta-2 microglobulin

decreases expression

EXP

nefazodone results in decreased expression of B2M mRNA

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356

G

bile acid CoA:amino acid N-acyltransferase

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of BAAT mRNA

NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181

G

BAG cochaperone 3

increases expression

EXP

nefazodone results in increased expression of BAG3 mRNA

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

EXP

nefazodone results in increased expression of BAIAP2L1 mRNA

NCBI chr12:15,364,090...15,453,602
Ensembl chr12:15,364,109...15,453,605

G

barrier to autointegration nuclear assembly factor 1

increases expression

EXP

nefazodone results in increased expression of BANF1 mRNA

NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552

G

Bcl-2 binding component 3

increases expression

ISO

nefazodone results in increased expression of BBC3 mRNA

NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666

G

gamma-butyrobetaine hydroxylase 1

decreases expression

EXP

nefazodone results in decreased expression of BBOX1 mRNA

NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064

G

B-cell receptor-associated protein 29

increases expression

EXP

nefazodone results in increased expression of BCAP29 mRNA

NCBI chr 6:53,910,209...53,950,206
Ensembl chr 6:53,910,216...53,949,963

G

branched chain ketoacid dehydrogenase kinase

decreases expression

EXP

nefazodone results in decreased expression of BCKDK mRNA

NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453

G

Bcl2-like 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of BCL2L1 mRNA

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

BCL6, transcription repressor

increases expression

EXP

nefazodone results in increased expression of BCL6 mRNA

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047

G

BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

increases expression

EXP

nefazodone results in increased expression of BCS1L mRNA

NCBI chr 9:83,614,045...83,618,052
Ensembl chr 9:83,613,975...83,618,257

G

Bet1 golgi vesicular membrane trafficking protein

increases expression

EXP

nefazodone results in increased expression of BET1 mRNA

NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164

G

biglycan

decreases expression

EXP

nefazodone results in decreased expression of BGN mRNA

NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799

G

betaine-homocysteine S-methyltransferase

decreases expression

EXP

nefazodone results in decreased expression of BHMT mRNA

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715

G

bridge-like lipid transfer protein family member 3B

increases expression

EXP

nefazodone results in increased expression of BLTP3B mRNA

NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083

G

biliverdin reductase B

increases expression

EXP

nefazodone results in increased expression of BLVRB mRNA

NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225

G

bone morphogenetic protein 1

decreases expression

EXP

nefazodone results in decreased expression of BMP1 mRNA

NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485

G

bone morphogenetic protein 6

increases expression

ISO

nefazodone results in increased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261

G

BCL2 interacting protein 3

increases expression

EXP

nefazodone results in increased expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962

G

BCL2 interacting protein 3 like

increases expression

EXP

nefazodone results in increased expression of BNIP3L mRNA

NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282

G

bolA family member 3

increases expression

EXP

nefazodone results in increased expression of BOLA3 mRNA

NCBI chr 4:117,411,044...117,420,491
Ensembl chr 4:117,410,680...117,420,491

G

BOP1 ribosomal biogenesis factor

increases expression

EXP

nefazodone results in increased expression of BOP1 mRNA

NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529

G

3'(2'), 5'-bisphosphate nucleotidase 1

increases expression

EXP

nefazodone results in increased expression of BPNT1 mRNA

NCBI chr13:99,397,127...99,425,056
Ensembl chr13:99,400,115...99,425,053

G

3'(2'), 5'-bisphosphate nucleotidase 2

increases expression

EXP

nefazodone results in increased expression of BPNT2 mRNA

NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126

G

bromodomain containing 10

decreases expression

EXP

nefazodone results in decreased expression of BRD10 mRNA

NCBI chr 1:227,490,983...227,572,246
Ensembl chr 1:236,904,520...236,983,923

G

bromodomain containing 3

decreases expression

EXP

nefazodone results in decreased expression of BRD3 mRNA

NCBI chr 3:31,173,332...31,227,749
Ensembl chr 3:31,173,332...31,227,629

G

biogenesis of ribosomes BRX1

increases expression

EXP

nefazodone results in increased expression of BRIX1 mRNA

NCBI chr 2:59,450,608...59,461,486
Ensembl chr 2:61,177,771...61,188,647

G

BRICK1 subunit of SCAR/WAVE actin nucleating complex

increases expression

EXP

nefazodone results in increased expression of BRK1 mRNA

NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:148,306,398...148,321,984

G

BTB domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of BTBD1 mRNA

NCBI chr 1:145,143,806...145,183,653
Ensembl chr 1:145,143,808...145,181,197

G

basic transcription factor 3

increases expression

EXP

nefazodone results in increased expression of BTF3 mRNA

NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125
Ensembl chr13:31,394,011...31,401,125

G

BTG anti-proliferation factor 1

decreases expression

EXP

nefazodone results in decreased expression of BTG1 mRNA

NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406

G

BUB3 mitotic checkpoint protein

increases expression

EXP

nefazodone results in increased expression of BUB3 mRNA

NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:195,758,105...195,791,028

G

bystin-like

increases expression

EXP

nefazodone results in increased expression of BYSL mRNA

NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:20,880,026...20,890,900

G

basic leucine zipper and W2 domains 1

increases expression

EXP

nefazodone results in increased expression of BZW1 mRNA

NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:67,424,866...67,439,684

G

similar to human chromosome 17 open reading frame 58

increases expression

EXP

nefazodone results in increased expression of C10H17ORF58 mRNA

NCBI chr10:92,472,779...92,477,330
Ensembl chr10:92,471,934...92,477,330

G

similar to human chromosome 5 open reading frame 15

increases expression

EXP

nefazodone results in increased expression of C10H5ORF15 mRNA

NCBI chr10:37,064,889...37,077,493
Ensembl chr10:37,064,728...37,077,493

G

similar to human chromosome 1 open reading frame 115

decreases expression

EXP

nefazodone results in decreased expression of C13H1ORF115 mRNA

NCBI chr13:98,953,841...98,963,577
Ensembl chr13:98,953,843...98,963,810

G

similar to human chromosome 18 open reading frame 32

increases expression

EXP

nefazodone results in increased expression of C18H18ORF32 mRNA

NCBI chr18:68,586,278...68,594,851
Ensembl chr18:70,861,435...70,869,983

G

C1GALT1-specific chaperone 1

increases expression

EXP

nefazodone results in increased expression of C1GALT1C1 mRNA

NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422

G

complement C1q binding protein

increases expression

EXP

nefazodone results in increased expression of C1QBP mRNA

NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235

G

complement C1r

decreases expression

EXP

nefazodone results in decreased expression of C1R mRNA

NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714

G

complement C1s

decreases expression

EXP

nefazodone results in decreased expression of C1S mRNA

NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736

G

complement C2

decreases expression

EXP

nefazodone results in decreased expression of C2 mRNA

NCBI chr20:3,944,722...3,975,006
Ensembl chr20:3,955,776...3,981,740

G

similar to human chromosome 6 open reading frame 89

increases expression

EXP

nefazodone results in increased expression of C20H6ORF89 mRNA

NCBI chr20:7,322,483...7,362,054
Ensembl chr20:7,324,129...7,363,666

G

complement C4B

decreases expression

EXP

nefazodone results in decreased expression of C4B mRNA

NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289

G

complement C5

decreases expression

EXP

nefazodone results in decreased expression of C5 mRNA

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468

G

similar to human chromosome 1 open reading frame 210

decreases expression

EXP

nefazodone results in decreased expression of C5H1ORF210 mRNA

NCBI chr 5:137,334,142...137,337,300
Ensembl chr 5:137,334,142...137,337,300

G

complement C6

decreases expression

EXP

nefazodone results in decreased expression of C6 mRNA

NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120

G

complement C8 alpha chain

decreases expression

EXP

nefazodone results in decreased expression of C8A mRNA

NCBI chr 5:124,812,131...124,866,631
Ensembl chr 5:124,812,131...124,866,710

G

complement C8 beta chain

decreases expression

EXP

nefazodone results in decreased expression of C8B mRNA

NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516

G

similar to human chromosome 11 open reading frame 54

increases expression

EXP

nefazodone results in increased expression of C8H11ORF54 mRNA

NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811

G

similar to human chromosome 11 open reading frame 65

increases expression

EXP

nefazodone results in increased expression of C8H11ORF65 mRNA

NCBI chr 8:62,692,123...62,720,951
Ensembl chr 8:62,692,568...62,720,946

G

complement C9

decreases expression

EXP

nefazodone results in decreased expression of C9 mRNA

NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752

G

similar to human chromosome 2 open reading frame 69

increases expression

EXP

nefazodone results in increased expression of C9H2ORF69 mRNA

NCBI chr 9:66,444,084...66,452,720
Ensembl chr 9:66,444,112...66,453,983

G

carbonic anhydrase 3

decreases expression

EXP

nefazodone results in decreased expression of CAR3 mRNA

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524

G

carbonic anhydrase 8

decreases expression

EXP

nefazodone results in decreased expression of CAR8 mRNA

NCBI chr 5:26,102,767...26,199,819
Ensembl chr 5:26,102,813...26,199,796

G

calcium binding protein 39

increases expression

EXP

nefazodone results in increased expression of CAB39 mRNA

NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542

G

calcium voltage-gated channel subunit alpha1 C

affects activity

ISO

nefazodone affects the activity of CACNA1C protein

NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CACNA2D1 mRNA

NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147

G

CDK2-associated, cullin domain 1

increases expression

EXP

nefazodone results in increased expression of CACUL1 mRNA

NCBI chr 1:259,666,335...259,726,249
Ensembl chr 1:269,652,356...269,712,112

G

calcyclin binding protein

increases expression

EXP

nefazodone results in increased expression of CACYBP mRNA

NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505

G

caldesmon 1

decreases expression

EXP

nefazodone results in decreased expression of CALD1 mRNA

NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085

G

calmodulin 2

decreases expression

EXP

nefazodone results in decreased expression of CALM2 mRNA

NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657

G

cell cycle associated protein 1

increases expression

EXP

nefazodone results in increased expression of CAPRIN1 mRNA

NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562

G

calcium regulated heat stable protein 1

decreases expression

EXP

nefazodone results in decreased expression of CARHSP1 mRNA

NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770

G

caspase 3

multiple interactions
increases expression
increases activity

ISO
EXP

Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP3 protein]
nefazodone results in increased expression of CASP3 mRNA

PMID:22700542 PMID:24136188 PMID:27288927

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 7

increases activity
multiple interactions

ISO

nefazodone results in increased activity of CASP7 protein
Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein]

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

caspase 9

increases activity

ISO

nefazodone results in increased activity of CASP9 protein

Ensembl chr 5:159,391,188...159,409,648

G

catalase

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of CAT mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CAT mRNA

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

caveolae associated protein 3

increases expression

EXP

nefazodone results in increased expression of CAVIN3 mRNA

NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981

G

carbonyl reductase 1

multiple interactions
increases expression

ISO
EXP

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CBR1 mRNA
nefazodone results in increased expression of CBR1 mRNA

PMID:24136188 PMID:32152650

NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104

G

carbonyl reductase 4

increases expression

EXP

nefazodone results in increased expression of CBR4 mRNA

NCBI chr16:33,625,734...33,695,067
Ensembl chr16:33,617,399...33,656,832

G

chromobox 3

increases expression

EXP

nefazodone results in increased expression of CBX3 mRNA

NCBI chr 4:81,876,155...81,889,912
Ensembl chr 4:81,876,649...81,889,911

G

coiled-coil domain containing 107

decreases expression

EXP

nefazodone results in decreased expression of CCDC107 mRNA

NCBI chr 5:62,545,273...62,548,711
Ensembl chr 5:62,544,714...62,548,709

G

coiled-coil domain containing 47

increases expression

EXP

nefazodone results in increased expression of CCDC47 mRNA

NCBI chr10:91,630,101...91,648,626
Ensembl chr10:91,630,106...91,648,626

G

coiled-coil domain containing 6

increases expression

EXP

nefazodone results in increased expression of CCDC6 mRNA

NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227

G

coiled-coil domain containing 80

decreases expression

EXP

nefazodone results in decreased expression of CCDC80 mRNA

NCBI chr11:69,191,188...69,224,844
Ensembl chr11:69,191,189...69,224,844

G

C-C motif chemokine ligand 9

decreases expression

EXP

nefazodone results in decreased expression of CCL6 mRNA; nefazodone results in decreased expression of CCL9 mRNA

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877

G

cyclin L1

decreases expression

EXP

nefazodone results in decreased expression of CCNL1 mRNA

NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468

G

cyclin L2

decreases expression

EXP

nefazodone results in decreased expression of CCNL2 mRNA

NCBI chr 5:171,698,951...171,711,037
Ensembl chr 5:171,699,689...171,711,231

G

C-C motif chemokine receptor 2

increases expression
multiple interactions

ISO

nefazodone results in increased expression of CCR2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059

G

copper chaperone for superoxide dismutase

increases expression

EXP

nefazodone results in increased expression of CCS mRNA

NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260

G

chaperonin containing TCP1 subunit 2

increases expression

EXP

nefazodone results in increased expression of CCT2 mRNA

NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977

G

chaperonin containing TCP1 subunit 3

increases expression

EXP

nefazodone results in increased expression of CCT3 mRNA

NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925

G

chaperonin containing TCP1 subunit 4

increases expression

EXP

nefazodone results in increased expression of CCT4 mRNA

NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770

G

chaperonin containing TCP1 subunit 5

increases expression

EXP

nefazodone results in increased expression of CCT5 mRNA

NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779

G

chaperonin containing TCP1 subunit 6A

increases expression

EXP

nefazodone results in increased expression of CCT6A mRNA

NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119

G

chaperonin containing TCP1 subunit 7

increases expression

EXP

nefazodone results in increased expression of CCT7 mRNA

NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973

G

chaperonin containing TCP1 subunit 8

increases expression

EXP

nefazodone results in increased expression of CCT8 mRNA

NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328

G

CD14 molecule

increases expression

EXP

nefazodone results in increased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

CD164 molecule

decreases expression

EXP

nefazodone results in decreased expression of CD164 mRNA

NCBI chr20:46,606,439...46,618,015
Ensembl chr20:46,606,107...46,638,649

G

CD302 molecule

decreases expression

EXP

nefazodone results in decreased expression of CD302 mRNA

NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737

G

Cd5 molecule-like

decreases expression

EXP

nefazodone results in decreased expression of CD5L mRNA

NCBI chr 2:175,088,915...175,099,928
Ensembl chr 2:175,088,884...175,099,926

G

CD74 molecule

decreases expression

EXP

nefazodone results in decreased expression of CD74 mRNA

NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410

G

Cd81 molecule

decreases expression

EXP

nefazodone results in decreased expression of CD81 mRNA

NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092

G

Cd82 molecule

decreases expression

EXP

nefazodone results in decreased expression of CD82 mRNA

NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:99,842,757...99,886,744

G

cell division cycle 40

increases expression

EXP

nefazodone results in increased expression of CDC40 mRNA

NCBI chr20:45,855,739...45,908,239
Ensembl chr20:45,855,739...45,907,978

G

cell division cycle 73

increases expression

EXP

nefazodone results in increased expression of CDC73 mRNA

NCBI chr13:57,897,924...58,000,031
Ensembl chr13:57,883,983...57,999,978

G

cadherin 2

decreases expression

EXP

nefazodone results in decreased expression of CDH2 mRNA

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cyclin-dependent kinase 4

increases expression

EXP

nefazodone results in increased expression of CDK4 mRNA

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin-dependent kinase 7

increases expression

EXP

nefazodone results in increased expression of CDK7 mRNA

NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485

G

cysteine dioxygenase type 1

decreases expression

EXP

nefazodone results in decreased expression of CDO1 mRNA

NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891

G

CEA cell adhesion molecule 1

decreases expression

EXP

nefazodone results in decreased expression of CEACAM1 mRNA

NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798

G

chymotrypsin like elastase 1

decreases expression

EXP

nefazodone results in decreased expression of CELA1 mRNA

NCBI chr 7:133,651,939...133,665,136
Ensembl chr 7:133,651,941...133,665,061

G

centromere protein V

increases expression

EXP

nefazodone results in increased expression of CENPV mRNA

NCBI chr10:47,713,778...47,746,800
Ensembl chr10:47,713,778...47,727,679

G

centrosomal protein 170

decreases expression

EXP

nefazodone results in decreased expression of CEP170 mRNA

NCBI chr13:91,201,808...91,285,990
Ensembl chr13:91,201,808...91,285,990

G

carboxylesterase 1E

increases expression

EXP

nefazodone results in increased expression of CES1E mRNA

NCBI chr19:13,833,154...13,869,627
Ensembl chr19:30,006,153...30,042,626

G

carboxylesterase 2H

increases expression

EXP

nefazodone results in increased expression of CES2 mRNA

NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752

G

cilia and flagella associated protein 20

increases expression

EXP

nefazodone results in increased expression of CFAP20 mRNA

NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612

G

cilia and flagella associated protein 298

increases expression

EXP

nefazodone results in increased expression of CFAP298 mRNA

NCBI chr11:43,667,996...43,678,049
Ensembl chr11:43,668,014...43,677,382

G

complement factor B

decreases expression

EXP

nefazodone results in decreased expression of CFB mRNA

NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740

G

complement factor H

decreases expression

EXP

nefazodone results in decreased expression of CFH mRNA

NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532

G

complement factor H-related 1

decreases expression

EXP

nefazodone results in decreased expression of CFHR1 mRNA

NCBI chr13:53,946,298...53,961,282
Ensembl chr13:53,919,927...53,961,303

G

cingulin

decreases expression

EXP

nefazodone results in decreased expression of CGN mRNA

NCBI chr 2:184,997,425...185,024,785
Ensembl chr 2:184,997,425...185,023,635

G

cingulin-like 1

decreases expression

EXP

nefazodone results in decreased expression of CGNL1 mRNA

NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747

G

cell growth regulator with ring finger domain 1

increases expression

EXP

nefazodone results in increased expression of CGRRF1 mRNA

NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811

G

ChaC glutathione specific gamma-glutamylcyclotransferase 2

decreases expression

EXP

nefazodone results in decreased expression of CHAC2 mRNA

NCBI chr14:108,921,669...108,929,215
Ensembl chr14:108,921,341...108,929,469

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

EXP

nefazodone results in increased expression of CHCHD10 mRNA

NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,277...12,745,677

G

coiled-coil-helix-coiled-coil-helix domain containing 2

increases expression

EXP

nefazodone results in increased expression of CHCHD2 mRNA

NCBI chr12:32,464,847...32,470,871
Ensembl chr12:32,464,824...32,470,871

G

coiled-coil-helix-coiled-coil-helix domain containing 5

increases expression

EXP

nefazodone results in increased expression of CHCHD5 mRNA

NCBI chr 3:116,361,845...116,372,238
Ensembl chr 3:136,815,048...136,821,914

G

coiled-coil-helix-coiled-coil-helix domain containing 6

increases expression

EXP

nefazodone results in increased expression of CHCHD6 mRNA

NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421

G

chitinase 3 like 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CHI3L1 mRNA

NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825

G

choline kinase alpha

decreases expression

EXP

nefazodone results in decreased expression of CHKA mRNA

NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752

G

charged multivesicular body protein 4C

increases expression

EXP

nefazodone results in increased expression of CHMP4C mRNA

NCBI chr 2:93,299,152...93,336,075
Ensembl chr 2:93,299,157...93,360,850

G

cysteine and histidine rich domain containing 1

increases expression

EXP

nefazodone results in increased expression of CHORDC1 mRNA

NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696

G

chondroitin polymerizing factor 2

increases expression

EXP

nefazodone results in increased expression of CHPF2 mRNA

NCBI chr 4:11,470,917...11,479,096
Ensembl chr 4:11,472,908...11,478,370

G

choline phosphotransferase 1

increases expression

EXP

nefazodone results in increased expression of CHPT1 mRNA

NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:24,750,343...24,802,521

G

chromatin accessibility complex subunit 1

increases expression

EXP

nefazodone results in increased expression of CHRAC1 mRNA

NCBI chr 7:106,901,841...106,905,441

G

component of inhibitor of nuclear factor kappa B kinase complex

increases expression

EXP

nefazodone results in increased expression of CHUK mRNA

NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273

G

churchill domain containing 1

increases expression

EXP

nefazodone results in increased expression of CHURC1 mRNA

NCBI chr 6:101,203,778...101,218,364
Ensembl chr 6:101,203,841...101,237,748

G

cytosolic iron-sulfur assembly component 2A

increases expression

EXP

nefazodone results in increased expression of CIAO2A mRNA

NCBI chr 8:75,565,620...75,577,542
Ensembl chr 8:75,565,567...75,577,541

G

cytokine induced apoptosis inhibitor 1

increases expression

EXP

nefazodone results in increased expression of CIAPIN1 mRNA

NCBI chr19:10,185,955...10,199,120
Ensembl chr19:10,182,088...10,201,495

G

cell death-inducing DFFA-like effector a

increases expression

EXP

nefazodone results in increased expression of CIDEA mRNA

NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382

G

cell death-inducing DFFA-like effector c

decreases expression

EXP

nefazodone results in decreased expression of CIDEC mRNA

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

EXP

nefazodone results in decreased expression of CITED2 mRNA

NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782

G

CDC28 protein kinase regulatory subunit 1B

increases expression

EXP

nefazodone results in increased expression of CKS1B mRNA

NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365

G

CDC28 protein kinase regulatory subunit 2

decreases expression

EXP

nefazodone results in decreased expression of CKS2 mRNA

NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519

G

chloride voltage-gated channel 3

increases expression

EXP

nefazodone results in increased expression of CLCN3 mRNA

NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984

G

chloride voltage-gated channel 4

decreases expression

EXP

nefazodone results in decreased expression of CLCN4 mRNA

NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939

G

claudin domain containing 1

increases expression

EXP

nefazodone results in increased expression of CLDND1 mRNA

NCBI chr11:55,352,321...55,358,779
Ensembl chr11:55,352,321...55,358,907

G

C-type lectin domain family 4, member F

decreases expression

EXP

nefazodone results in decreased expression of CLEC4F mRNA

NCBI chr 4:117,686,686...117,696,407
Ensembl chr 4:117,686,686...117,696,438

G

CAP-GLY domain containing linker protein 1

increases expression

EXP

nefazodone results in increased expression of CLIP1 mRNA

NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779

G

caseinolytic mitochondrial matrix peptidase proteolytic subunit

increases expression

EXP

nefazodone results in increased expression of CLPP mRNA

NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705

G

clathrin, light chain B

increases expression

EXP

nefazodone results in increased expression of CLTB mRNA

NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,006,656...10,024,915

G

clathrin heavy chain

increases expression

EXP

nefazodone results in increased expression of CLTC mRNA

NCBI chr10:72,014,984...72,073,308
Ensembl chr10:72,014,986...72,070,691

G

cytidine monophosphate N-acetylneuraminic acid synthetase

increases expression

EXP

nefazodone results in increased expression of CMAS mRNA

NCBI chr 4:177,449,801...177,468,117
Ensembl chr 4:177,449,732...177,476,291

G

carboxymethylenebutenolidase homolog

increases expression

EXP

nefazodone results in increased expression of CMBL mRNA

NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:84,242,512...84,301,880

G

CKLF-like MARVEL transmembrane domain containing 6

decreases expression

EXP

nefazodone results in decreased expression of CMTM6 mRNA

NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230

G

CKLF-like MARVEL transmembrane domain containing 8

increases expression

EXP

nefazodone results in increased expression of CMTM8 mRNA

NCBI chr 8:123,360,168...123,425,291
Ensembl chr 8:123,360,170...123,425,276

G

CCR4-NOT transcription complex, subunit 11

increases expression

EXP

nefazodone results in increased expression of CNOT11 mRNA

NCBI chr 9:41,814,923...41,824,626
Ensembl chr 9:49,309,518...49,321,771

G

cytochrome C oxidase assembly factor 3

increases expression

EXP

nefazodone results in increased expression of COA3 mRNA

NCBI chr10:86,220,192...86,221,173
Ensembl chr10:86,720,456...86,721,440

G

cytochrome C oxidase assembly factor 5

increases expression

EXP

nefazodone results in increased expression of COA5 mRNA

NCBI chr 9:47,147,267...47,160,724
Ensembl chr 9:47,147,267...47,160,672

G

Coenzyme A synthase

increases expression

EXP

nefazodone results in increased expression of COASY mRNA

NCBI chr10:86,514,850...86,519,130
Ensembl chr10:86,514,874...86,519,130

G

component of oligomeric golgi complex 6

increases expression

EXP

nefazodone results in increased expression of COG6 mRNA

NCBI chr 2:137,062,127...137,099,176
Ensembl chr 2:139,211,678...139,249,737

G

collagen type XIV alpha 1 chain

decreases expression

EXP

nefazodone results in decreased expression of COL14A1 mRNA

NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938

G

collagen type XVIII alpha 1 chain

decreases expression

EXP

nefazodone results in decreased expression of COL18A1 mRNA

NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112

G

collagen type I alpha 2 chain

decreases expression

EXP

nefazodone results in decreased expression of COL1A2 mRNA

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type III alpha 1 chain

decreases expression

EXP

nefazodone results in decreased expression of COL3A1 mRNA

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

collagen type VI alpha 1 chain

decreases expression

EXP

nefazodone results in decreased expression of COL6A1 mRNA

NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107

G

COMM domain containing 5

increases expression

EXP

nefazodone results in increased expression of COMMD5 mRNA

NCBI chr 7:110,502,492...110,503,916
Ensembl chr 7:110,479,403...110,505,897

G

catechol-O-methyltransferase domain containing 1

increases expression

EXP

nefazodone results in increased expression of COMTD1 mRNA

NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,509,032...2,512,232

G

COPI coat complex subunit epsilon

increases expression

EXP

nefazodone results in increased expression of COPE mRNA

NCBI chr16:19,148,832...19,159,052
Ensembl chr16:19,148,832...19,159,212

G

COP9 signalosome subunit 4

increases expression

EXP

nefazodone results in increased expression of COPS4 mRNA

NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,382,900...9,413,107

G

COP9 signalosome subunit 5

increases expression

EXP

nefazodone results in increased expression of COPS5 mRNA

NCBI chr 5:13,975,198...13,993,391
Ensembl chr 5:13,975,052...13,993,387

G

COP9 signalosome subunit 7A

increases expression

EXP

nefazodone results in increased expression of COPS7A mRNA

NCBI chr 4:159,452,878...159,478,878
Ensembl chr 4:159,452,897...159,460,315

G

coenzyme Q10A

decreases expression

EXP

nefazodone results in decreased expression of COQ10A mRNA

NCBI chr 7:1,376,591...1,387,694
Ensembl chr 7:1,376,591...1,382,722

G

coenzyme Q6 monooxygenase

increases expression

EXP

nefazodone results in increased expression of COQ6 mRNA

NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310

G

coenzyme Q8A

decreases expression

EXP

nefazodone results in decreased expression of COQ8A mRNA

NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378

G

coronin 1C

decreases expression

EXP

nefazodone results in decreased expression of CORO1C mRNA

NCBI chr12:48,373,573...48,445,718
Ensembl chr12:48,373,597...48,445,716

G

cytochrome c oxidase assembly factor COX14

increases expression

EXP

nefazodone results in increased expression of COX14 mRNA

NCBI chr 7:132,731,069...132,733,159
Ensembl chr 7:132,731,069...132,733,159

G

cytochrome c oxidase assembly factor COX19

increases expression

EXP

nefazodone results in increased expression of COX19 mRNA

NCBI chr12:20,417,389...20,426,868
Ensembl chr12:20,417,341...20,426,868

G

ceruloplasmin

decreases expression

EXP

nefazodone results in decreased expression of CP mRNA

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087

G

carboxypeptidase B2

decreases expression

EXP

nefazodone results in decreased expression of CPB2 mRNA

NCBI chr15:56,967,128...57,015,964
Ensembl chr15:56,966,839...57,015,962

G

coproporphyrinogen oxidase

increases expression

EXP

nefazodone results in increased expression of CPOX mRNA

NCBI chr11:55,405,778...55,415,761
Ensembl chr11:55,405,784...55,415,761

G

carboxypeptidase Q

decreases expression

EXP

nefazodone results in decreased expression of PGCP mRNA

NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137

G

carbamoyl-phosphate synthase 1

decreases expression

EXP

nefazodone results in decreased expression of CPS1 mRNA

NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734

G

cleavage and polyadenylation specific factor 3

increases expression

EXP

nefazodone results in increased expression of CPSF3 mRNA

NCBI chr 6:46,564,855...46,592,776
Ensembl chr 6:46,564,735...46,594,136

G

carnitine palmitoyltransferase 1A

increases expression

EXP

nefazodone results in increased expression of CPT1A mRNA

NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326

G

carnitine palmitoyltransferase 2

increases expression

EXP

nefazodone results in increased expression of CPT2 mRNA

NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818

G

carnitine O-acetyltransferase

increases expression

EXP

nefazodone results in increased expression of CRAT mRNA

NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099

G

cAMP responsive element binding protein 3

increases expression

EXP

nefazodone results in increased expression of CREB3 mRNA

NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:62,613,638...62,619,500

G

cAMP responsive element binding protein 3-like 3

increases expression

EXP

nefazodone results in increased expression of CREB3L3 mRNA

NCBI chr 7:9,273,320...9,281,755
Ensembl chr 7:9,273,338...9,281,778

G

cellular repressor of E1A-stimulated genes 1

increases expression

EXP

nefazodone results in increased expression of CREG1 mRNA

NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272

G

cysteine-rich with EGF-like domains 1

increases expression

EXP

nefazodone results in increased expression of CRELD1 mRNA

NCBI chr 4:148,187,510...148,197,120
Ensembl chr 4:148,187,265...148,197,116

G

cAMP responsive element modulator

decreases expression

EXP

nefazodone results in decreased expression of CREM mRNA

NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160

G

cysteine-rich protein 2

decreases expression

EXP

nefazodone results in decreased expression of CRIP2 mRNA

NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120

G

carnitine O-octanoyltransferase

decreases expression

EXP

nefazodone results in decreased expression of CROT mRNA

NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064

G

cryptochrome circadian regulator 1

decreases expression

EXP

nefazodone results in decreased expression of CRY1 mRNA

NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822

G

crystallin beta-gamma domain containing 2

decreases expression

EXP

nefazodone results in decreased expression of CRYBG2 mRNA

NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:151,570,540...151,602,163

G

crystallin, lambda 1

increases expression

EXP

nefazodone results in increased expression of CRYL1 mRNA

NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563

G

chromosome segregation 1 like

increases expression

EXP

nefazodone results in increased expression of CSE1L mRNA

NCBI chr 3:176,060,183...176,097,909
Ensembl chr 3:176,060,215...176,108,734

G

colony stimulating factor 1

decreases expression
increases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of CSF1 mRNA
nefazodone results in increased expression of CSF1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CSF1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468

G

colony stimulating factor 1 receptor

decreases expression

EXP

nefazodone results in decreased expression of CSF1R mRNA

NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806

G

cysteine and glycine-rich protein 1

decreases expression

EXP

nefazodone results in decreased expression of CSRP1 mRNA

NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139

G

cystathionine gamma-lyase

decreases expression

EXP

nefazodone results in decreased expression of CTH mRNA

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066

G

cathepsin C

decreases expression

EXP

nefazodone results in decreased expression of CTSC mRNA

NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082

G

cathepsin D

increases expression

EXP

nefazodone results in increased expression of CTSD mRNA

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cathepsin H

decreases expression

EXP

nefazodone results in decreased expression of CTSH mRNA

NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181

G

cathepsin L

increases expression

EXP

nefazodone results in increased expression of CTSL mRNA

NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113

G

cortactin

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of CTTN mRNA

NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211

G

C-X-C motif chemokine ligand 12

decreases expression

EXP

nefazodone results in decreased expression of CXCL12 mRNA

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

CXXC finger protein 5

decreases expression

EXP

nefazodone results in decreased expression of CXXC5 mRNA

NCBI chr18:27,701,650...27,732,633
Ensembl chr18:27,701,188...27,732,635

G

cytochrome b5 type A

increases expression

EXP

nefazodone results in increased expression of CYB5A mRNA

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094

G

cytochrome b-245 beta chain

decreases expression

EXP

nefazodone results in decreased expression of CYBB mRNA

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065

G

CYLD lysine 63 deubiquitinase

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CYLD mRNA
nefazodone results in increased expression of CYLD mRNA

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
decreases activity

EXP
ISO

nefazodone results in increased expression of CYP1A1 mRNA
nefazodone results in decreased activity of CYP1A1 protein

PMID:24136188 PMID:33814510

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of CYP1A2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP1A2 mRNA

PMID:24136188 PMID:33819548

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases activity

ISO

nefazodone results in decreased activity of CYP1B1 protein

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

cytochrome P450, family 20, subfamily a, polypeptide 1

increases expression

EXP

nefazodone results in increased expression of CYP20A1 mRNA

NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291

G

cytochrome P450, family 27, subfamily a, polypeptide 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP27A1 mRNA

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215

G

cytochrome P450, family 2, subfamily b, polypeptide 12

increases expression

EXP

nefazodone results in increased expression of CYP2B12 mRNA

NCBI chr 1:91,135,294...91,147,094
Ensembl chr 1:91,135,294...91,208,159

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of CYP2B3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP2B6 mRNA
nefazodone results in decreased expression of CYP2B6 mRNA

PMID:24136188 PMID:32152650

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, subfamily 2, polypeptide 11

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C18 mRNA

NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853

G

cytochrome P450, family 2, subfamily c, polypeptide 13

decreases expression

EXP

nefazodone results in decreased expression of CYP2C13 mRNA

NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210

G

cytochrome P450, family 2, subfamily c, polypeptide 22

decreases expression

EXP

nefazodone results in decreased expression of CYP2C22 mRNA

NCBI chr 1:248,941,143...248,980,767
Ensembl chr 1:248,904,062...248,971,182

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C19 mRNA

NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression

EXP

nefazodone results in increased expression of CYP2E1 mRNA

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily j, polypeptide 3

decreases expression

EXP

nefazodone results in decreased expression of CYP2J3 mRNA

NCBI chr 5:116,335,755...116,360,677
Ensembl chr 5:116,335,755...116,360,499

G

cytochrome P450, family 2, subfamily t, polypeptide 1

decreases expression

EXP

nefazodone results in decreased expression of CYP2T1 mRNA

NCBI chr 1:91,573,923...91,579,215
Ensembl chr 1:91,574,572...91,579,215

G

cytochrome P450, family 3, subfamily a, polypeptide 18

increases expression

EXP

nefazodone results in increased expression of CYP3A18 mRNA

NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases expression
increases response to substance
multiple interactions
increases hydroxylation

ISO

nefazodone results in decreased expression of CYP3A4 mRNA
CYP3A4 protein results in increased susceptibility to nefazodone
[CYP3A4 protein results in increased hydroxylation of nefazodone] which results in increased abundance of hydroxynefazodone; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP3A4 mRNA; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of nefazodone]; nefazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]

PMID:12584149 PMID:21540358 PMID:27485346 PMID:32152650

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions
increases expression

ISO
EXP

nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]
nefazodone results in increased expression of CYP3A9 mRNA

PMID:12584149 PMID:24136188

NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154

G

cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

EXP

nefazodone results in increased expression of CYP4A1 mRNA

NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231

G

cytochrome P450, family 4, subfamily a, polypeptide 3

increases expression

EXP

nefazodone results in increased expression of CYP4A3 mRNA

NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236

G

cytochrome P450, family 4, subfamily f, polypeptide 1

decreases expression

EXP

nefazodone results in decreased expression of CYP4F1 mRNA

NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612

G

cytochrome P450, family 4, subfamily f, polypeptide 6

decreases expression

EXP

nefazodone results in decreased expression of CYP4F6 mRNA

NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions
decreases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA
nefazodone results in decreased expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

cytochrome P450 family 7 subfamily B member 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP7B1 mRNA

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804

G

cytochrome P450 family 8 subfamily B member 1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of CYP8B1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP8B1 mRNA

PMID:24136188 PMID:33819548

NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689

G

dishevelled associated activator of morphogenesis 1

decreases expression

EXP

nefazodone results in decreased expression of DAAM1 mRNA

NCBI chr 6:96,125,521...96,286,049
Ensembl chr 6:96,125,621...96,286,049

G

dystroglycan 1

decreases expression

EXP

nefazodone results in decreased expression of DAG1 mRNA

NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199

G

D-amino-acid oxidase

increases expression

EXP

nefazodone results in increased expression of DAO mRNA

NCBI chr12:48,252,900...48,275,964
Ensembl chr12:48,252,902...48,273,300

G

aspartyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of DARS1 mRNA

NCBI chr13:42,410,351...42,465,467
Ensembl chr13:42,379,162...42,465,467

G

DDB1 and CUL4 associated factor 11

increases expression

EXP

nefazodone results in increased expression of DCAF11 mRNA

NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672

G

DDB1 and CUL4 associated factor 13

increases expression

EXP

nefazodone results in increased expression of DCAF13 mRNA

NCBI chr 7:72,045,828...72,081,039
Ensembl chr 7:72,045,872...72,083,629

G

dopa decarboxylase

decreases expression

EXP

nefazodone results in decreased expression of DDC mRNA

NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806

G

DDHD domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of DDHD1 mRNA

NCBI chr15:21,304,053...21,370,608
Ensembl chr15:21,303,826...21,370,608

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

ISO

nefazodone results in increased expression of DDIT3 mRNA; nefazodone results in increased expression of DDIT3 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DDIT3 mRNA

PMID:24136188 PMID:27613715 PMID:32152650

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DEAD-box helicase 17

decreases expression

EXP

nefazodone results in decreased expression of DDX17 mRNA

NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747

G

DExD-box helicase 21

increases expression

EXP

nefazodone results in increased expression of DDX21 mRNA

NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238

G

DExD-box helicase 39A

increases expression

EXP

nefazodone results in increased expression of DDX39A mRNA

NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306

G

DEAD-box helicase 56

increases expression

EXP

nefazodone results in increased expression of DDX56 mRNA

NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262

G

2,4-dienoyl-CoA reductase 1

increases expression

EXP

nefazodone results in increased expression of DECR1 mRNA

NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033

G

2,4-dienoyl-CoA reductase 2

increases expression

EXP

nefazodone results in increased expression of DECR2 mRNA

NCBI chr10:15,609,389...15,617,779
Ensembl chr10:15,611,092...15,617,397

G

delta(4)-desaturase, sphingolipid 1

increases expression

EXP

nefazodone results in increased expression of DEGS1 mRNA

NCBI chr13:96,478,645...96,485,302
Ensembl chr13:96,478,646...96,485,302

G

DENN domain containing 4C

increases expression

EXP

nefazodone results in increased expression of DENND4C mRNA

NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:106,318,281...106,415,489

G

desumoylating isopeptidase 1

increases expression

EXP

nefazodone results in increased expression of DESI1 mRNA

NCBI chr 7:115,401,613...115,422,974
Ensembl chr 7:115,401,624...115,423,172

G

desumoylating isopeptidase 2

increases expression

EXP

nefazodone results in increased expression of DESI2 mRNA

NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981

G

Dexi homolog

decreases expression

EXP

nefazodone results in decreased expression of DEXI mRNA

NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,632,961...5,645,648

G

diacylglycerol O-acyltransferase 1

increases expression

EXP

nefazodone results in increased expression of DGAT1 mRNA

NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016

G

diacylglycerol kinase, alpha

decreases expression

EXP

nefazodone results in decreased expression of DGKA mRNA

NCBI chr 7:1,733,247...1,761,181
Ensembl chr 7:1,733,248...1,759,569

G

diacylglycerol kinase zeta

decreases expression

EXP

nefazodone results in decreased expression of DGKZ mRNA

NCBI chr 3:98,359,804...98,401,847
Ensembl chr 3:98,359,804...98,401,951

G

dehydrodolichyl diphosphate synthase subunit

increases expression

EXP

nefazodone results in increased expression of DHDDS mRNA

NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:151,481,429...151,508,129

G

dehydrogenase/reductase 4

increases expression

EXP

nefazodone results in increased expression of DHRS4 mRNA

NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101

G

dehydrogenase E1 and transketolase domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of DHTKD1 mRNA

NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071

G

DEAH-box helicase 15

increases expression

EXP

nefazodone results in increased expression of DHX15 mRNA

NCBI chr14:62,999,886...63,037,829
Ensembl chr14:62,999,877...63,037,828

G

diablo, IAP-binding mitochondrial protein

increases expression

EXP

nefazodone results in increased expression of DIABLO mRNA

NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265

G

DLC1 Rho GTPase activating protein

decreases expression

EXP

nefazodone results in decreased expression of DLC1 mRNA

NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819

G

dimethylglycine dehydrogenase

decreases expression

EXP

nefazodone results in decreased expression of DMGDH mRNA

NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071

G

dynein axonemal assembly factor 9

decreases expression

EXP

nefazodone results in decreased expression of DNAAF9 mRNA

NCBI chr 3:117,918,047...118,052,641
Ensembl chr 3:138,372,531...138,505,695

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression

EXP

nefazodone results in increased expression of DNAJA1 mRNA

NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160

G

DnaJ heat shock protein family (Hsp40) member A2

increases expression

EXP

nefazodone results in increased expression of DNAJA2 mRNA

NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120

G

DnaJ heat shock protein family (Hsp40) member A3

increases expression

EXP

nefazodone results in increased expression of DNAJA3 mRNA

NCBI chr10:11,361,168...11,386,599
Ensembl chr10:11,361,168...11,386,599

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of DNAJB1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB1 mRNA

PMID:24136188 PMID:32152650

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416

G

DnaJ heat shock protein family (Hsp40) member B11

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB11 mRNA

NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800

G

DnaJ heat shock protein family (Hsp40) member B12

increases expression

EXP

nefazodone results in increased expression of DNAJB12 mRNA

NCBI chr20:28,371,180...28,389,390
Ensembl chr20:28,371,199...28,389,389

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of DNAJB9 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJB9 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB9 mRNA

PMID:24136188 PMID:32152650 PMID:33819548

NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344

G

DnaJ heat shock protein family (Hsp40) member C1

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC1 mRNA
nefazodone results in increased expression of DNAJC1 mRNA

NCBI chr17:80,955,209...81,112,025
Ensembl chr17:85,863,651...86,020,432

G

DnaJ heat shock protein family (Hsp40) member C10

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC10 mRNA
nefazodone results in increased expression of DNAJC10 mRNA

NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368

G

DnaJ heat shock protein family (Hsp40) member C12

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of DNAJC12 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJC12 mRNA

PMID:24136188 PMID:33819548

NCBI chr20:25,245,475...25,266,238
Ensembl chr20:25,222,298...25,266,251

G

DnaJ heat shock protein family (Hsp40) member C15

increases expression

EXP

nefazodone results in increased expression of DNAJC15 mRNA

NCBI chr15:59,594,314...59,658,862
Ensembl chr15:59,594,314...59,658,987

G

DnaJ heat shock protein family (Hsp40) member C18

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC18 mRNA

NCBI chr18:27,543,438...27,577,535
Ensembl chr18:27,543,438...27,577,535

G

DnaJ heat shock protein family (Hsp40) member C19

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of DNAJC19 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of DNAJC19 mRNA

NCBI chr 2:118,851,497...118,875,813
Ensembl chr 2:118,869,413...118,873,781

G

DnaJ heat shock protein family (Hsp40) member C21

multiple interactions
decreases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of DNAJC21 mRNA
nefazodone results in decreased expression of DNAJC21 mRNA

NCBI chr 2:61,146,669...61,173,908
Ensembl chr 2:61,145,142...61,174,126

G

DnaJ heat shock protein family (Hsp40) member C3

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC3 mRNA

NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643

G

DnaJ heat shock protein family (Hsp40) member C6

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC6 mRNA
nefazodone results in increased expression of DNAJC6 mRNA

NCBI chr 5:121,232,532...121,398,775
Ensembl chr 5:121,235,425...121,398,775

G

DNL-type zinc finger

increases expression

EXP

nefazodone results in increased expression of DNLZ mRNA

NCBI chr 3:29,568,041...29,569,937
Ensembl chr 3:29,568,041...29,569,996

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

increases expression

EXP

nefazodone results in increased expression of DNPH1 mRNA

NCBI chr 9:21,978,894...21,981,631
Ensembl chr 9:21,978,894...21,981,631

G

deoxynucleotidyltransferase, terminal, interacting protein 1

increases expression

EXP

nefazodone results in increased expression of DNTTIP1 mRNA

NCBI chr 3:173,901,070...173,924,742
Ensembl chr 3:173,900,945...173,925,098

G

dedicator of cytokinesis 9

increases expression

EXP

nefazodone results in increased expression of DOCK9 mRNA

NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799

G

deoxyhypusine hydroxylase

increases expression

EXP

nefazodone results in increased expression of DOHH mRNA

NCBI chr 7:8,972,202...8,977,025
Ensembl chr 7:8,972,202...8,977,025

G

diphthamide biosynthesis 3

increases expression

EXP

nefazodone results in increased expression of DPH3 mRNA

NCBI chr16:7,294,580...7,299,996
Ensembl chr16:7,294,580...7,299,996

G

dolichyl-phosphate mannosyltransferase subunit 1, catalytic

increases expression

EXP

nefazodone results in increased expression of DPM1 mRNA

NCBI chr 3:177,338,855...177,358,398
Ensembl chr 3:177,338,855...177,358,412

G

dpy-19 like C-mannosyltransferase 1

decreases expression

EXP

nefazodone results in decreased expression of DPY19L1 mRNA

NCBI chr 8:31,209,025...31,297,485
Ensembl chr 8:31,209,025...31,297,518

G

dpy-30 histone methyltransferase complex regulatory subunit

increases expression

EXP

nefazodone results in increased expression of DPY30 mRNA

NCBI chr 6:26,872,812...26,893,580
Ensembl chr 6:26,872,732...26,894,930

G

dihydropyrimidinase

decreases expression

EXP

nefazodone results in decreased expression of DPYS mRNA

NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:72,721,048...72,814,142

G

down-regulator of transcription 1

increases expression

EXP

nefazodone results in increased expression of DR1 mRNA

NCBI chr14:1,603,203...1,614,556
Ensembl chr14:1,603,204...1,614,556

G

desmocollin 2

increases expression

EXP

nefazodone results in increased expression of DSC2 mRNA

NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466

G

destrin, actin depolymerizing factor

increases expression

EXP

nefazodone results in increased expression of DSTN mRNA

NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769

G

D-aminoacyl-tRNA deacylase 1

increases expression

EXP

nefazodone results in increased expression of DTD1 mRNA

NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:152,452,620...152,486,304

G

deoxyuridine triphosphatase

increases expression

EXP

nefazodone results in increased expression of DUT mRNA

NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956

G

dynein cytoplasmic 1 heavy chain 1

increases expression

EXP

nefazodone results in increased expression of DYNC1H1 mRNA

NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116

G

dynein light chain LC8-type 2

increases expression

EXP

nefazodone results in increased expression of DYNLL2 mRNA

NCBI chr10:73,264,260...73,283,042
Ensembl chr10:73,264,261...73,272,285

G

dynein light chain Tctex-type 3

decreases expression

EXP

nefazodone results in decreased expression of DYNLT3 mRNA

NCBI chr X:16,000,425...16,009,632
Ensembl chr X:16,000,395...16,009,627

G

EBNA1 binding protein 2

increases expression

EXP

nefazodone results in increased expression of EBNA1BP2 mRNA

NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637

G

EBP, cholestenol delta-isomerase

decreases expression

EXP

nefazodone results in decreased expression of EBP mRNA

NCBI chr X:16,971,372...16,977,782
Ensembl chr X:16,971,405...16,977,781

G

EBP like

increases expression

EXP

nefazodone results in increased expression of EBPL mRNA

NCBI chr15:39,684,140...39,707,537
Ensembl chr15:39,684,140...39,707,537

G

enoyl-CoA hydratase 1

increases expression

EXP

nefazodone results in increased expression of ECH1 mRNA

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440

G

ethylmalonyl-CoA decarboxylase 1

decreases expression

EXP

nefazodone results in decreased expression of ECHDC1 mRNA

NCBI chr 1:30,304,968...30,355,957
Ensembl chr 1:30,304,971...30,337,208

G

enoyl-CoA delta isomerase 1

increases expression

EXP

nefazodone results in increased expression of ECI1 mRNA

NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773

G

extracellular matrix protein 1

decreases expression

EXP

nefazodone results in decreased expression of ECM1 mRNA

NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606

G

Ecm29 proteasome adaptor and scaffold

increases expression

EXP

nefazodone results in increased expression of ECPAS mRNA

NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908

G

ECSIT signaling integrator

increases expression

EXP

nefazodone results in increased expression of ECSIT mRNA

NCBI chr 8:28,881,594...28,894,443
Ensembl chr 8:28,881,594...28,894,397

G

eukaryotic translation elongation factor 1 beta 2

increases expression

EXP

nefazodone results in increased expression of EEF1B2 mRNA

NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:72,073,802...72,076,589

G

eukaryotic translation elongation factor 1 delta

increases expression

EXP

nefazodone results in increased expression of EEF1D mRNA

NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531

G

eukaryotic translation elongation factor 1 epsilon 1

increases expression

EXP

nefazodone results in increased expression of EEF1E1 mRNA

NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687

G

ephrin A1

decreases expression

EXP

nefazodone results in decreased expression of EFNA1 mRNA

NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726

G

epidermal growth factor

decreases expression

EXP

nefazodone results in decreased expression of EGF mRNA

NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297

G

epidermal growth factor receptor

decreases expression

EXP

nefazodone results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

EH domain binding protein 1

decreases expression

EXP

nefazodone results in decreased expression of EHBP1 mRNA

NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579

G

eukaryotic translation initiation factor 1A

increases expression

EXP

nefazodone results in increased expression of EIF1A mRNA

NCBI chr18:39,325,695...39,338,043
Ensembl chr18:41,503,180...41,549,696

G

eukaryotic translation initiation factor 1A domain containing

increases expression

EXP

nefazodone results in increased expression of EIF1AD mRNA

NCBI chr 1:212,103,715...212,109,015
Ensembl chr 1:212,103,892...212,109,017

G

eukaryotic translation initiation factor 2A

multiple interactions
increases expression

ISO

2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of EIF2A protein modified form]

NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201

G

eukaryotic translation initiation factor 2 alpha kinase 1

decreases expression

EXP

nefazodone results in decreased expression of EIF2AK1 mRNA

NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281

G

eukaryotic translation initiation factor 2B subunit epsilon

increases expression

EXP

nefazodone results in increased expression of EIF2B5 mRNA

NCBI chr11:93,898,814...93,909,431
Ensembl chr11:93,898,814...93,908,800

G

eukaryotic translation initiation factor 2 subunit alpha

increases expression

EXP

nefazodone results in increased expression of EIF2S1 mRNA

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649

G

eukaryotic translation initiation factor 2 subunit beta

increases expression

EXP

nefazodone results in increased expression of EIF2S2 mRNA

NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570

G

eukaryotic translation initiation factor 2 subunit gamma

increases expression

EXP

nefazodone results in increased expression of EIF2S3X mRNA

NCBI chr X:62,910,292...62,933,936
Ensembl chr X:62,910,293...62,934,489

G

eukaryotic translation initiation factor 3, subunit B

increases expression

EXP

nefazodone results in increased expression of EIF3B mRNA

NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939

G

eukaryotic translation initiation factor 3, subunit C

increases expression

EXP

nefazodone results in increased expression of EIF3C mRNA

NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067

G

eukaryotic translation initiation factor 3 subunit E

increases expression

EXP

nefazodone results in increased expression of EIF3E mRNA

NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:76,224,568...76,257,785

G

eukaryotic translation initiation factor 3, subunit G

increases expression

EXP

nefazodone results in increased expression of EIF3G mRNA

NCBI chr 8:27,705,914...27,709,946
Ensembl chr 8:27,705,915...27,709,987

G

eukaryotic translation initiation factor 3, subunit I

increases expression

EXP

nefazodone results in increased expression of EIF3I mRNA

NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232

G

eukaryotic translation initiation factor 3, subunit L

increases expression

EXP

nefazodone results in increased expression of EIF3L mRNA

NCBI chr 7:112,522,222...112,544,063
Ensembl chr 7:112,507,831...112,544,062

G

eukaryotic translation initiation factor 3, subunit M

increases expression

EXP

nefazodone results in increased expression of EIF3M mRNA

NCBI chr 3:111,879,589...111,897,193
Ensembl chr 3:111,870,925...111,897,193

G

eukaryotic translation initiation factor 4A1

increases expression

EXP

nefazodone results in increased expression of EIF4A1 mRNA

NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602

G

eukaryotic translation initiation factor 4E

increases expression

EXP

nefazodone results in increased expression of EIF4E mRNA

NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

EXP

nefazodone results in increased expression of EIF4EBP1 mRNA

NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874

G

eukaryotic translation initiation factor 4E binding protein 2

increases expression

EXP

nefazodone results in increased expression of EIF4EBP2 mRNA

NCBI chr20:29,922,260...29,942,922
Ensembl chr20:29,922,260...29,942,922

G

eukaryotic translation initiation factor 4 gamma 1

increases expression

EXP

nefazodone results in increased expression of EIF4G1 mRNA

NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367

G

eukaryotic translation initiation factor 5

increases expression

EXP

nefazodone results in increased expression of EIF5 mRNA

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821

G

eukaryotic translation initiation factor 5A

increases expression

EXP

nefazodone results in increased expression of EIF5A mRNA

NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330

G

eukaryotic translation initiation factor 6

increases expression

EXP

nefazodone results in increased expression of EIF6 mRNA

NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525

G

elaC ribonuclease Z 2

increases expression

EXP

nefazodone results in increased expression of ELAC2 mRNA

NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069

G

ELAV like RNA binding protein 1

increases expression

EXP

nefazodone results in increased expression of ELAVL1 mRNA

NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631

G

elongin C

increases expression

EXP

nefazodone results in increased expression of ELOC mRNA

NCBI chr 5:7,444,769...7,461,187
Ensembl chr 5:7,445,018...7,464,128
Ensembl chr20:7,445,018...7,464,128

G

ELOVL fatty acid elongase 2

increases expression

EXP

nefazodone results in increased expression of ELOVL2 mRNA

NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601

G

ELOVL fatty acid elongase 5

decreases expression

EXP

nefazodone results in decreased expression of ELOVL5 mRNA

NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616

G

elongator acetyltransferase complex subunit 2

increases expression

EXP

nefazodone results in increased expression of ELP2 mRNA

NCBI chr18:15,885,940...15,921,564
Ensembl chr18:16,160,671...16,196,414

G

ER membrane protein complex subunit 1

increases expression

EXP

nefazodone results in increased expression of EMC1 mRNA

NCBI chr 5:156,891,773...156,917,092
Ensembl chr 5:156,891,773...156,917,092

G

ER membrane protein complex subunit 10

increases expression

EXP

nefazodone results in increased expression of EMC10 mRNA

NCBI chr 1:104,119,040...104,125,409
Ensembl chr 1:104,119,040...104,125,368

G

ER membrane protein complex subunit 6

increases expression

EXP

nefazodone results in increased expression of EMC6 mRNA

NCBI chr10:57,794,072...57,795,671
Ensembl chr10:58,292,470...58,298,885

G

ER membrane protein complex subunit 7

increases expression

EXP

nefazodone results in increased expression of EMC7 mRNA

NCBI chr 3:119,714,617...119,728,748
Ensembl chr 3:119,718,357...119,730,486

G

ER membrane protein complex subunit 8

increases expression

EXP

nefazodone results in increased expression of EMC8 mRNA

NCBI chr19:65,620,365...65,630,328
Ensembl chr19:65,620,375...65,630,235

G

elastin microfibril interfacer 1

decreases expression

EXP

nefazodone results in decreased expression of EMILIN1 mRNA

NCBI chr 6:31,175,919...31,183,657
Ensembl chr 6:31,175,919...31,183,657

G

EMAP like 4

decreases expression

EXP

nefazodone results in decreased expression of EML4 mRNA

NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439

G

ectodermal-neural cortex 1

multiple interactions
decreases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of ENC1 mRNA
nefazodone results in decreased expression of ENC1 mRNA

NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

EXP

nefazodone results in decreased expression of ENPP1 mRNA

NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044

G

ectonucleoside triphosphate diphosphohydrolase 4

increases expression

EXP

nefazodone results in increased expression of ENTPD4 mRNA

NCBI chr15:51,040,665...51,068,450
Ensembl chr15:51,040,673...51,068,441

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

EXP

nefazodone results in increased expression of ENTPD5 mRNA

NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495

G

endosome associated trafficking regulator 1

increases expression

EXP

nefazodone results in increased expression of ENTR1 mRNA

NCBI chr 3:29,599,059...29,605,780
Ensembl chr 3:29,599,059...29,605,898

G

erythrocyte membrane protein band 4.1

increases expression

EXP

nefazodone results in increased expression of EPB41 mRNA

NCBI chr 5:149,394,080...149,548,178
Ensembl chr 5:149,394,096...149,543,540

G

erythrocyte membrane protein band 4.1 like 4B

decreases expression

EXP

nefazodone results in decreased expression of EPB41L4B mRNA

NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752

G

epoxide hydrolase 1

increases expression
multiple interactions
decreases expression

EXP
ISO

nefazodone results in increased expression of EPHX1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA
nefazodone results in decreased expression of EPHX1 mRNA

PMID:24136188 PMID:32152650

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

glutamyl-prolyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of EPRS1 mRNA

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509

G

epiregulin

increases expression

ISO

nefazodone results in increased expression of EREG mRNA

NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260

G

ERI1 exoribonuclease family member 3

increases expression

EXP

nefazodone results in increased expression of ERI3 mRNA

NCBI chr 5:131,016,146...131,143,347
Ensembl chr 5:136,252,683...136,379,815

G

ER lipid raft associated 1

increases expression

EXP

nefazodone results in increased expression of ERLIN1 mRNA

NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:252,870,356...252,905,947

G

endoplasmic reticulum metallopeptidase 1

increases expression

EXP

nefazodone results in increased expression of ERMP1 mRNA

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197

G

ERBB receptor feedback inhibitor 1

decreases expression

EXP

nefazodone results in decreased expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432

G

esterase D

increases expression

EXP

nefazodone results in increased expression of ESD mRNA

NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508

G

eukaryotic translation termination factor 1

increases expression

EXP

nefazodone results in increased expression of ETF1 mRNA

NCBI chr18:26,776,518...26,804,857
Ensembl chr18:26,777,858...26,804,613

G

ETHE1, persulfide dioxygenase

decreases expression

EXP

nefazodone results in decreased expression of ETHE1 mRNA

NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998

G

ethanolamine kinase 1

increases expression

EXP

nefazodone results in increased expression of ETNK1 mRNA

NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721

G

exosome component 4

increases expression

EXP

nefazodone results in increased expression of EXOSC4 mRNA

NCBI chr 7:109,928,491...109,931,233
Ensembl chr 7:109,928,498...109,931,820

G

exosome component 5

increases expression

EXP

nefazodone results in increased expression of EXOSC5 mRNA

NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046

G

exosome component 7

increases expression

EXP

nefazodone results in increased expression of EXOSC7 mRNA

NCBI chr 8:122,773,607...122,798,943
Ensembl chr 8:131,651,050...131,696,825

G

coagulation factor X

decreases expression

EXP

nefazodone results in decreased expression of F10 mRNA

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280

G

fatty acid amide hydrolase

decreases expression

EXP

nefazodone results in decreased expression of FAAH mRNA

NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396

G

fatty acid binding protein 5

decreases expression

EXP

nefazodone results in decreased expression of FABP5 mRNA

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127

G

fatty acid binding protein 7

decreases expression

EXP

nefazodone results in decreased expression of FABP7 mRNA

NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907

G

fatty acid desaturase 1

decreases expression

EXP

nefazodone results in decreased expression of FADS1 mRNA

NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615

G

fatty acid desaturase 2

decreases expression

EXP

nefazodone results in decreased expression of FADS2 mRNA

NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066

G

Fas associated factor 1

increases expression

EXP

nefazodone results in increased expression of FAF1 mRNA

NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:129,654,445...130,020,516

G

family with sequence similarity 117, member B

decreases expression

EXP

nefazodone results in decreased expression of FAM117B mRNA

NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:68,834,354...68,902,543

G

family with sequence similarity 136, member A

increases expression

EXP

nefazodone results in increased expression of FAM136A mRNA

NCBI chr 4:120,362,563...120,368,479
Ensembl chr 4:120,362,561...120,368,479

G

family with sequence similarity 193, member B

decreases expression

EXP

nefazodone results in decreased expression of FAM193B mRNA

NCBI chr17:9,066,818...9,099,511
Ensembl chr17:9,071,795...9,104,656

G

FAM3 metabolism regulating signaling molecule A

increases expression

EXP

nefazodone results in increased expression of FAM3A mRNA

NCBI chr X:157,317,993...157,326,640
Ensembl chr X:157,317,990...157,326,612

G

family with sequence similarity 89, member A

decreases expression

EXP

nefazodone results in decreased expression of FAM89A mRNA

NCBI chr19:69,607,391...69,620,019
Ensembl chr19:69,607,391...69,620,019

G

family with sequence similarity 91, member A1

increases expression

EXP

nefazodone results in increased expression of FAM91A1 mRNA

NCBI chr 7:89,969,558...90,007,546
Ensembl chr 7:91,859,062...91,898,195

G

phenylalanyl-tRNA synthetase subunit beta

increases expression

EXP

nefazodone results in increased expression of FARSB mRNA

NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:87,336,326...87,395,505

G

fatty acid synthase

decreases expression

EXP

nefazodone results in decreased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

fibrillarin

increases expression

EXP

nefazodone results in increased expression of FBL mRNA

NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506

G

F-box protein 21

increases expression

EXP

nefazodone results in increased expression of FBXO21 mRNA

NCBI chr12:44,231,918...44,266,035
Ensembl chr12:44,231,923...44,266,035

G

F-box protein 31

increases expression

EXP

nefazodone results in increased expression of FBXO31 mRNA

NCBI chr19:66,533,437...66,564,674
Ensembl chr19:66,533,437...66,564,674

G

F-box protein 4

increases expression

EXP

nefazodone results in increased expression of FBXO4 mRNA

NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:54,902,394...54,915,388

G

F-box protein 7

increases expression

EXP

nefazodone results in increased expression of FBXO7 mRNA

NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:19,696,961...19,725,180

G

Fc gamma receptor 2A

decreases expression

EXP

nefazodone results in decreased expression of FCGR2A mRNA

NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394

G

ficolin A

decreases expression

EXP

nefazodone results in decreased expression of FCNA mRNA

NCBI chr 3:28,844,036...28,847,441
Ensembl chr 3:28,844,039...28,847,237

G

ferredoxin 1

increases expression

EXP

nefazodone results in increased expression of FDX1 mRNA

NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583

G

ferrochelatase

increases expression

EXP

nefazodone results in increased expression of FECH mRNA

NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546

G

fibrinogen alpha chain

decreases expression

EXP

nefazodone results in decreased expression of FGA mRNA

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

fibrinogen beta chain

decreases expression

EXP

nefazodone results in decreased expression of FGB mRNA

NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434

G

fibroblast growth factor 21

increases expression

EXP

nefazodone results in increased expression of FGF21 mRNA

NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056

G

fibroblast growth factor receptor 2

decreases expression

EXP

nefazodone results in decreased expression of FGFR2 mRNA

NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914

G

fibrinogen gamma chain

decreases expression

EXP

nefazodone results in decreased expression of FGG mRNA

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170

G

FGGY carbohydrate kinase domain containing

decreases expression

EXP

nefazodone results in decreased expression of FGGY mRNA

NCBI chr 5:115,514,573...115,901,713
Ensembl chr 5:115,472,211...115,901,714

G

fibrinogen-like 1

decreases expression

EXP

nefazodone results in decreased expression of FGL1 mRNA

NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429

G

FKBP prolyl isomerase 11

increases expression

EXP

nefazodone results in increased expression of FKBP11 mRNA

NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123

G

FKBP prolyl isomerase 1A

increases expression

EXP

nefazodone results in increased expression of FKBP1A mRNA

NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233

G

FKBP prolyl isomerase 3

increases expression

EXP

nefazodone results in increased expression of FKBP3 mRNA

NCBI chr 6:88,850,137...88,862,542
Ensembl chr 6:88,843,879...88,863,447

G

FKBP prolyl isomerase 5

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of FKBP5 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FKBP5 mRNA

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118

G

folliculin

increases expression

EXP

nefazodone results in increased expression of FLCN mRNA

NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309

G

flotillin 1

decreases expression

EXP

nefazodone results in decreased expression of FLOT1 mRNA

NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771

G

FLYWCH-type zinc finger 1

increases expression

EXP

nefazodone results in increased expression of FLYWCH1 mRNA

NCBI chr10:13,279,232...13,298,955
Ensembl chr10:13,279,232...13,298,925

G

flavin containing dimethylaniline monoxygenase 1

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of FMO1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FMO1 mRNA

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

fibronectin 1

decreases expression

EXP

nefazodone results in decreased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

fibronectin type III domain containing 3B

increases expression

EXP

nefazodone results in increased expression of FNDC3B mRNA

NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

nefazodone results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of FOSL1 mRNA
nefazodone results in increased expression of FOSL1 mRNA

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391

G

forkhead box A2

decreases expression

EXP

nefazodone results in decreased expression of FOXA2 mRNA

NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757

G

forkhead box N3

decreases expression

EXP

nefazodone results in decreased expression of FOXN3 mRNA

NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040

G

forkhead box O3

increases expression

ISO

nefazodone results in increased expression of FOXO3 mRNA

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

follistatin-like 1

decreases expression

EXP

nefazodone results in decreased expression of FSTL1 mRNA

NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126

G

formimidoyltransferase cyclodeaminase

increases expression

EXP

nefazodone results in increased expression of FTCD mRNA

NCBI chr20:12,054,710...12,068,219
Ensembl chr20:12,054,711...12,068,237

G

ferritin light chain 1

increases expression

EXP

nefazodone results in increased expression of FTL1 mRNA

NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915

G

Fus RNA binding protein

decreases expression

EXP

nefazodone results in decreased expression of FUS mRNA

NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884

G

FMR1 autosomal homolog 1

increases expression

EXP

nefazodone results in increased expression of FXR1 mRNA

NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:118,811,980...118,867,027

G

frizzled class receptor 1

decreases expression

EXP

nefazodone results in decreased expression of FZD1 mRNA

NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176

G

frizzled class receptor 8

decreases expression

EXP

nefazodone results in decreased expression of FZD8 mRNA

NCBI chr17:62,007,849...62,015,485
Ensembl chr17:62,007,627...62,015,961

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

EXP

nefazodone results in decreased expression of G6PC1 mRNA

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033

G

alpha glucosidase

increases expression

EXP

nefazodone results in increased expression of GAA mRNA

NCBI chr10:105,028,106...105,045,365
Ensembl chr10:105,028,307...105,045,366

G

growth arrest and DNA-damage-inducible, alpha

increases expression

EXP

nefazodone results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

galactokinase 1

increases expression

EXP

nefazodone results in increased expression of GALK1 mRNA

NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258

G

galactose mutarotase

decreases expression

EXP

nefazodone results in decreased expression of GALM mRNA

NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417

G

glycyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of GARS1 mRNA

NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876

G

growth arrest specific 5

increases expression

EXP

nefazodone results in increased expression of GAS5 mRNA

NCBI chr13:75,836,963...75,840,284

G

growth arrest specific 6

decreases expression

EXP

nefazodone results in decreased expression of GAS6 mRNA

NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088

G

GC, vitamin D binding protein

decreases expression

EXP

nefazodone results in decreased expression of GC mRNA

NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673

G

glycine C-acetyltransferase

decreases expression

EXP

nefazodone results in decreased expression of GCAT mRNA

NCBI chr 7:112,475,572...112,481,920
Ensembl chr 7:112,475,496...112,482,664

G

GTP cyclohydrolase 1

increases expression

EXP

nefazodone results in increased expression of GCH1 mRNA

NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412

G

glucokinase

decreases expression

EXP

nefazodone results in decreased expression of GCK mRNA

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949

G

glucokinase regulator

decreases expression

EXP

nefazodone results in decreased expression of GCKR mRNA

NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627

G

glutamate-cysteine ligase, catalytic subunit

increases expression

EXP

nefazodone results in increased expression of GCLC mRNA

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamate cysteine ligase, modifier subunit

increases expression

EXP

nefazodone results in increased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

guanine deaminase

increases expression

EXP

nefazodone results in increased expression of GDA mRNA

NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348

G

glycerophosphodiester phosphodiesterase 1

increases expression

EXP

nefazodone results in increased expression of GDE1 mRNA

NCBI chr 1:182,451,182...182,466,569
Ensembl chr 1:182,451,184...182,466,772

G

gem (nuclear organelle) associated protein 6

increases expression

EXP

nefazodone results in increased expression of GEMIN6 mRNA

NCBI chr 6:20,538,325...20,542,867
Ensembl chr 6:20,538,325...20,542,852

G

guided entry of tail-anchored proteins factor 4

increases expression

EXP

nefazodone results in increased expression of GET4 mRNA

NCBI chr12:20,490,861...20,508,096
Ensembl chr12:20,490,861...20,555,240

G

gamma-glutamyl hydrolase

increases expression

EXP

nefazodone results in increased expression of GGH mRNA

NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647

G

gamma-glutamyltransferase 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GGT1 mRNA

NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050

G

growth hormone inducible transmembrane protein

increases expression

EXP

nefazodone results in increased expression of GHITM mRNA

NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,905,806...12,918,123

G

growth hormone receptor

decreases expression

EXP

nefazodone results in decreased expression of GHR mRNA

NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331

G

gap junction protein, beta 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GJB1 mRNA

NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843

G

gap junction protein, beta 2

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of GJB2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GJB2 mRNA

PMID:24136188 PMID:33819548

NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877

G

glycerol kinase

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GK mRNA

NCBI chr X:54,106,708...54,189,940
Ensembl chr X:54,112,214...54,196,701

G

glycine decarboxylase

decreases expression

EXP

nefazodone results in decreased expression of GLDC mRNA

NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604

G

glutaredoxin

increases expression

EXP

nefazodone results in increased expression of GLRX mRNA

NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543

G

glutaredoxin 2

increases expression

EXP

nefazodone results in increased expression of GLRX2 mRNA

NCBI chr13:58,032,199...58,055,061
Ensembl chr13:58,032,401...58,043,150

G

glutaredoxin 3

increases expression

EXP

nefazodone results in increased expression of GLRX3 mRNA

NCBI chr 1:201,671,410...201,701,722
Ensembl chr 1:201,671,481...201,701,717

G

glutaredoxin 5

increases expression

EXP

nefazodone results in increased expression of GLRX5 mRNA

NCBI chr 6:129,752,902...129,763,278
Ensembl chr 6:129,752,840...129,763,278

G

glutaminase 2

decreases expression

EXP

nefazodone results in decreased expression of GLS2 mRNA

NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013

G

glutamate dehydrogenase 1

decreases expression

EXP

nefazodone results in decreased expression of GLUD1 mRNA

NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210

G

glutamate-ammonia ligase

decreases expression

EXP

nefazodone results in decreased expression of GLUL mRNA

NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520

G

glycine-N-acyltransferase-like 2

increases expression

EXP

nefazodone results in increased expression of GLYATL2 mRNA

NCBI chr 1:209,807,488...209,840,480
Ensembl chr 1:219,232,103...219,266,322

G

ganglioside GM2 activator

decreases expression

EXP

nefazodone results in decreased expression of GM2A mRNA

NCBI chr10:39,719,919...39,732,452
Ensembl chr10:39,719,938...39,732,451

G

guanine monophosphate synthase

increases expression

EXP

nefazodone results in increased expression of GMPS mRNA

NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986

G

G protein subunit alpha i2

decreases expression

EXP

nefazodone results in decreased expression of GNAI2 mRNA

NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:117,167,045...117,187,622

G

G protein subunit alpha i3

increases expression

EXP

nefazodone results in increased expression of GNAI3 mRNA

NCBI chr 2:198,430,920...198,468,874

G

GNAS complex locus

decreases expression

EXP

nefazodone results in decreased expression of GNAS mRNA

NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

EXP

nefazodone results in decreased expression of GNE mRNA

NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:63,062,850...63,103,251

G

G protein nucleolar 3

increases expression

EXP

nefazodone results in increased expression of GNL3 mRNA

NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,213,871...6,219,845

G

G protein nucleolar 3 like

increases expression

EXP

nefazodone results in increased expression of GNL3L mRNA

NCBI chr X:23,404,324...23,437,501
Ensembl chr X:23,404,324...23,439,315

G

glycine N-methyltransferase

decreases expression

EXP

nefazodone results in decreased expression of GNMT mRNA

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692

G

glucosamine (N-acetyl)-6-sulfatase

decreases expression

EXP

nefazodone results in decreased expression of GNS mRNA

NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650

G

golgi phosphoprotein 3

increases expression

EXP

nefazodone results in increased expression of GOLPH3 mRNA

NCBI chr 2:63,072,610...63,103,091
Ensembl chr 2:63,074,256...63,113,577

G

golgi transport 1A

increases expression

EXP

nefazodone results in increased expression of GOLT1A mRNA

NCBI chr13:44,760,356...44,773,123
Ensembl chr13:47,322,002...47,325,175

G

golgi associated PDZ and coiled-coil motif containing

increases expression

EXP

nefazodone results in increased expression of GOPC mRNA

NCBI chr20:32,270,314...32,319,635
Ensembl chr20:32,270,314...32,319,611

G

glutamic-oxaloacetic transaminase 1

decreases expression

EXP

nefazodone results in decreased expression of GOT1 mRNA

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glycerol-3-phosphate acyltransferase 4

increases expression

EXP

nefazodone results in increased expression of GPAT4 mRNA

NCBI chr16:75,515,935...75,555,431
Ensembl chr16:75,521,640...75,557,847

G

glycerol-3-phosphate dehydrogenase 1

increases expression

EXP

nefazodone results in increased expression of GPD1 mRNA

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368

G

glucose-6-phosphate isomerase

increases expression

EXP

nefazodone results in increased expression of GPI mRNA

NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

EXP

nefazodone results in decreased expression of GPLD1 mRNA

NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975

G

G protein-coupled receptor, class C, group 5, member B

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GPRC5B mRNA

NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:182,748,247...182,772,757

G

glutathione peroxidase 1

decreases expression

EXP

nefazodone results in decreased expression of GPX1 mRNA

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione peroxidase 2

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of GPX2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GPX2 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GPX2 mRNA

PMID:32152650 PMID:33819548

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862

G

glutathione peroxidase 4

increases expression

EXP

nefazodone results in increased expression of GPX4 mRNA

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629

G

GRAM domain containing 2B

increases expression

EXP

nefazodone results in increased expression of GRAMD2B mRNA

NCBI chr18:52,082,128...52,180,056
Ensembl chr18:52,082,029...52,180,054

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

increases expression

EXP

nefazodone results in increased expression of GRINA mRNA

NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042

G

glutamate-rich WD repeat containing 1

increases expression

EXP

nefazodone results in increased expression of GRWD1 mRNA

NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:105,437,709...105,443,825

G

glutathione-disulfide reductase

increases expression

EXP

nefazodone results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione synthetase

increases expression

EXP

nefazodone results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306

G

glutathione S-transferase alpha 1

multiple interactions
decreases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTA1 mRNA
nefazodone results in decreased expression of GSTA1 mRNA

NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528

G

glutathione S-transferase alpha 2

increases expression

EXP

nefazodone results in increased expression of GSTA2 mRNA

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase alpha 3

increases expression

EXP

nefazodone results in increased expression of GSTA3 mRNA

NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654

G

glutathione S-transferase alpha 4

increases expression

EXP

nefazodone results in increased expression of GSTA4 mRNA

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488

G

glutathione S-transferase mu 1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of GSTM1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 2

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of GSTM2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM2 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase mu 4

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of GSTM4 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM4 mRNA

PMID:24136188 PMID:32152650

NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638

G

glutathione S-transferase pi 1

increases expression

EXP

nefazodone results in increased expression of GSTP1 mRNA

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase pi 3

decreases expression

EXP

nefazodone results in decreased expression of GSTP3 mRNA

NCBI chr 1:210,785,151...210,787,705
Ensembl chr 1:210,785,151...210,787,684

G

glutathione S-transferase, theta 3

increases expression

EXP

nefazodone results in increased expression of GSTT3 mRNA

NCBI chr20:12,873,618...12,881,974
Ensembl chr20:12,874,374...12,881,973

G

general transcription factor IIB

increases expression

EXP

nefazodone results in increased expression of GTF2B mRNA

NCBI chr 2:234,427,734...234,446,043
Ensembl chr 2:234,427,637...234,446,049

G

general transcription factor IIH subunit 1

increases expression

EXP

nefazodone results in increased expression of GTF2H1 mRNA

NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727

G

general transcription factor III A

increases expression

EXP

nefazodone results in increased expression of GTF3A mRNA

NCBI chr12:13,250,643...13,258,587
Ensembl chr12:13,250,644...13,258,587

G

guanylate cyclase 1 soluble subunit beta 2

decreases expression

EXP

nefazodone results in decreased expression of GUCY1B2 mRNA

NCBI chr15:40,774,907...40,845,463
Ensembl chr15:40,774,906...40,845,463

G

gulonolactone (L-) oxidase

decreases expression

EXP

nefazodone results in decreased expression of GULO mRNA

NCBI chr15:40,205,677...40,227,766
Ensembl chr15:44,381,214...44,403,422

G

glucuronidase, beta

decreases expression

EXP

nefazodone results in decreased expression of GUSB mRNA

NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024

G

H1.0 linker histone

decreases expression

EXP

nefazodone results in decreased expression of H1F0 mRNA

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006

G

H2A.Z variant histone 2

decreases expression

EXP

nefazodone results in decreased expression of H2AZ2 mRNA

NCBI chr14:85,507,228...85,526,166
Ensembl chr14:85,507,228...85,526,207
Ensembl chr16:85,507,228...85,526,207

G

H3.3 histone B

increases expression

EXP

nefazodone results in increased expression of H3F3B mRNA

NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636

G

3-hydroxyacyl-CoA dehydratase 3

increases expression

EXP

nefazodone results in increased expression of HACD3 mRNA

NCBI chr 8:74,396,441...74,433,700
Ensembl chr 8:74,396,442...74,433,700

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

EXP

nefazodone results in increased expression of HADHA mRNA

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

EXP

nefazodone results in increased expression of HADHB mRNA

NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835

G

hydroxyacyl glutathione hydrolase

decreases expression

EXP

nefazodone results in decreased expression of HAGH mRNA

NCBI chr10:14,379,400...14,394,046
Ensembl chr10:14,382,410...14,394,043

G

histidine ammonia lyase

decreases expression

EXP

nefazodone results in decreased expression of HAL mRNA

NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744

G

hepcidin antimicrobial peptide

decreases expression

EXP

nefazodone results in decreased expression of HAMP mRNA

NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297

G

hydroxyacid oxidase 1

decreases expression

EXP

nefazodone results in decreased expression of HAO1 mRNA

NCBI chr 3:142,102,873...142,281,527
Ensembl chr 3:142,224,612...142,281,494

G

hydroxyacid oxidase 2

decreases expression

EXP

nefazodone results in decreased expression of HAO2 mRNA

NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133

G

histidyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of HARS1 mRNA

NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712

G

hemoglobin alpha, adult chain 1

decreases expression

EXP

nefazodone results in decreased expression of HBA-A1 mRNA

NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603

G

hemoglobin alpha, adult chain 2

decreases expression

EXP

nefazodone results in decreased expression of HBA1 mRNA

NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141

G

histone deacetylase 2

decreases expression

EXP

nefazodone results in decreased expression of HDAC2 mRNA

NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311

G

histone deacetylase 6

increases expression

EXP

nefazodone results in increased expression of HDAC6 mRNA

NCBI chr X:17,222,538...17,244,373
Ensembl chr X:17,222,856...17,244,370

G

heparin binding growth factor

increases expression

EXP

nefazodone results in increased expression of HDGF mRNA

NCBI chr 2:175,668,290...175,677,614
Ensembl chr 2:175,668,324...175,677,225

G

helicase with zinc finger 2

decreases expression

EXP

nefazodone results in decreased expression of HELZ2 mRNA

NCBI chr 3:188,716,370...188,730,776
Ensembl chr 3:188,716,370...188,730,716

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of HERPUD1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of HERPUD1 mRNA

PMID:24136188 PMID:32152650

NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081

G

hes family bHLH transcription factor 6

decreases expression

EXP

nefazodone results in decreased expression of HES6 mRNA

NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096

G

hexosaminidase subunit alpha

decreases expression

EXP

nefazodone results in decreased expression of HEXA mRNA

NCBI chr 8:68,832,524...68,857,462
Ensembl chr 8:68,809,615...68,859,560

G

HEXIM P-TEFb complex subunit 1

decreases expression

EXP

nefazodone results in decreased expression of HEXIM1 mRNA

NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,560,519...88,580,000

G

homeostatic iron regulator

increases expression

EXP

nefazodone results in increased expression of HFE mRNA

NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208

G

homogentisate 1, 2-dioxygenase

decreases expression

EXP

nefazodone results in decreased expression of HGD mRNA

NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767

G

hepatocyte growth factor

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of HGF mRNA

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851

G

hepatocyte growth factor-regulated tyrosine kinase substrate

increases expression

EXP

nefazodone results in increased expression of HGS mRNA

NCBI chr10:106,237,988...106,256,174
Ensembl chr10:106,237,824...106,256,174

G

hematopoietically expressed homeobox

decreases expression

EXP

nefazodone results in decreased expression of HHEX mRNA

NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

EXP

nefazodone results in increased expression of HIBCH mRNA

NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886

G

HIG1 hypoxia inducible domain family, member 1A

increases expression

EXP

nefazodone results in increased expression of HIGD1A mRNA

NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888

G

heat shock protein nuclear import factor hikeshi

increases expression

EXP

nefazodone results in increased expression of HIKESHI mRNA

NCBI chr 1:153,237,948...153,261,856
Ensembl chr 1:153,237,948...153,261,911

G

histidine triad nucleotide binding protein 2

increases expression

EXP

nefazodone results in increased expression of HINT2 mRNA

NCBI chr 5:62,700,383...62,702,638
Ensembl chr 5:62,700,384...62,702,915

G

histone cluster 1 H4 family member B

decreases expression

EXP

nefazodone results in decreased expression of HIST1H4B mRNA

NCBI chr17:47,176,246...47,180,690
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr 4:41,797,152...41,806,539

G

holocarboxylase synthetase

increases expression

EXP

nefazodone results in increased expression of HLCS mRNA

NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082

G

hydroxymethylbilane synthase

increases expression

EXP

nefazodone results in increased expression of HMBS mRNA

NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:53,570,364...53,577,802

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

EXP

nefazodone results in increased expression of HMGCR mRNA

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

EXP

nefazodone results in decreased expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

high mobility group nucleosome binding domain 1

increases expression

EXP

nefazodone results in increased expression of HMGN1 mRNA

NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771

G

heme oxygenase 1

increases expression

EXP

nefazodone results in increased expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heterogeneous nuclear ribonucleoprotein A2/B1

decreases expression

EXP

nefazodone results in decreased expression of HNRNPA2B1 mRNA

NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572

G

heterogeneous nuclear ribonucleoprotein A/B

increases expression

EXP

nefazodone results in increased expression of HNRNPAB mRNA

NCBI chr10:36,358,004...36,363,898
Ensembl chr10:36,358,006...36,364,307

G

heterogeneous nuclear ribonucleoprotein F

increases expression

EXP

nefazodone results in increased expression of HNRNPF mRNA

NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769

G

4-hydroxy-2-oxoglutarate aldolase 1

decreases expression

EXP

nefazodone results in decreased expression of HOGA1 mRNA

NCBI chr 1:250,806,430...250,833,544
Ensembl chr 1:250,806,255...250,833,869

G

homer scaffold protein 1

increases expression

EXP

nefazodone results in increased expression of HOMER1 mRNA

NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:26,278,105...26,381,657

G

hypoxanthine phosphoribosyltransferase 1

increases expression

EXP

nefazodone results in increased expression of HPRT1 mRNA

NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712

G

hemopexin

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of HPX mRNA

NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156

G

hydroxysteroid (17-beta) dehydrogenase 4

increases expression

EXP

nefazodone results in increased expression of HSD17B4 mRNA

NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467

G

hydroxysteroid (17-beta) dehydrogenase 6

decreases expression

EXP

nefazodone results in decreased expression of HSD17B6 mRNA

NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5

decreases expression

EXP

nefazodone results in decreased expression of HSD3B5 mRNA

NCBI chr 2:188,697,669...188,717,141
Ensembl chr 2:188,697,670...188,709,118

G

hydroxysteroid dehydrogenase like 2

increases expression

EXP

nefazodone results in increased expression of HSDL2 mRNA

NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798

G

heat shock transcription factor 2

increases expression

EXP

nefazodone results in increased expression of HSF2 mRNA

NCBI chr20:37,366,301...37,393,922
Ensembl chr20:37,366,279...37,401,022

G

heat shock protein 90 alpha family class A member 1

increases expression

EXP

nefazodone results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein 90 alpha family class B member 1

increases expression

EXP

nefazodone results in increased expression of HSP90AB1 mRNA

NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926

G

heat shock protein family A (Hsp70) member 5

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of HSPA5 mRNA
nefazodone results in increased expression of HSPA5 mRNA

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 8

increases expression

EXP

nefazodone results in increased expression of HSPA8 mRNA

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family A (Hsp70) member 9

increases expression

EXP

nefazodone results in increased expression of HSPA9 mRNA

NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398

G

heat shock protein family B (small) member 1

increases expression

EXP

nefazodone results in increased expression of HSPB1 mRNA

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heat shock protein family B (small) member 8

increases expression

EXP

nefazodone results in increased expression of HSPB8 mRNA

NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937

G

HSPA (Hsp70) binding protein 1

increases expression

EXP

nefazodone results in increased expression of HSPBP1 mRNA

NCBI chr 1:78,194,067...78,217,836
Ensembl chr 1:78,189,305...78,217,835

G

heat shock protein family D (Hsp60) member 1

increases expression

EXP

nefazodone results in increased expression of HSPD1 mRNA

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037

G

heat shock protein family E (Hsp10) member 1

increases expression

EXP

nefazodone results in increased expression of HSPE1 mRNA

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

heat shock protein family H (Hsp110) member 1

increases expression

EXP

nefazodone results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891

G

HIV-1 Tat interactive protein 2

increases expression

EXP

nefazodone results in increased expression of HTATIP2 mRNA

NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815

G

5-hydroxytryptamine receptor 1A

affects binding

ISO

nefazodone binds to HTR1A protein

NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760

G

5-hydroxytryptamine receptor 2C

affects binding

ISO

nefazodone binds to HTR2C protein

NCBI chr X:115,453,190...115,682,325
Ensembl chr X:115,452,842...115,682,324

G

HtrA serine peptidase 1

decreases expression

EXP

nefazodone results in decreased expression of HTRA1 mRNA

NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620

G

hyaluronidase 3

decreases expression

EXP

nefazodone results in decreased expression of HYAL3 mRNA

NCBI chr 8:117,133,028...117,138,663
Ensembl chr 8:117,132,649...117,139,289

G

hyccin PI4KA lipid kinase complex subunit 2

increases expression

EXP

nefazodone results in increased expression of HYCC2 mRNA

NCBI chr 9:67,551,064...67,623,353
Ensembl chr 9:67,551,064...67,587,186

G

isoleucyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of IARS1 mRNA

NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652

G

isoleucyl-tRNA synthetase 2, mitochondrial

increases expression

EXP

nefazodone results in increased expression of IARS2 mRNA

NCBI chr13:99,363,035...99,397,068
Ensembl chr13:99,362,696...99,397,068

G

iron-sulfur cluster assembly factor IBA57

increases expression

EXP

nefazodone results in increased expression of IBA57 mRNA

NCBI chr10:44,441,579...44,450,368
Ensembl chr10:44,441,579...44,450,368

G

intercellular adhesion molecule 1

decreases expression

EXP

nefazodone results in decreased expression of ICAM1 mRNA

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

inhibitor of DNA binding 4

decreases expression

EXP

nefazodone results in decreased expression of ID4 mRNA

NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492

G

insulin degrading enzyme

increases expression

EXP

nefazodone results in increased expression of IDE mRNA

NCBI chr 1:244,415,495...244,516,925
Ensembl chr 1:244,416,343...244,514,526

G

isocitrate dehydrogenase (NADP(+)) 1

increases expression

EXP

nefazodone results in increased expression of IDH1 mRNA

NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555

G

immediate early response 3

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of IER3 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of IER3 mRNA

PMID:24136188 PMID:33819548

NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377

G

interferon, alpha-inducible protein 27

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of IFI27 mRNA

NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781

G

interferon-induced protein 35

increases expression

EXP

nefazodone results in increased expression of IFI35 mRNA

NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750

G

interferon induced transmembrane protein 1

decreases expression

EXP

nefazodone results in decreased expression of IFITM1 mRNA

NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776

G

interferon gamma

multiple interactions

ISO
EXP

[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interferon-related developmental regulator 1

increases expression

EXP

nefazodone results in increased expression of IFRD1 mRNA

NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131

G

interferon-related developmental regulator 2

increases expression

EXP

nefazodone results in increased expression of IFRD2 mRNA

NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836

G

insulin-like growth factor 1

decreases expression

EXP

nefazodone results in decreased expression of IGF1 mRNA

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764

G

insulin-like growth factor binding protein, acid labile subunit

decreases expression

EXP

nefazodone results in decreased expression of IGFALS mRNA

NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138

G

insulin-like growth factor binding protein 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of IGFBP1 mRNA

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344

G

insulin-like growth factor binding protein 3

decreases expression

EXP

nefazodone results in decreased expression of IGFBP3 mRNA

NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944

G

insulin-like growth factor binding protein 4

decreases expression

EXP

nefazodone results in decreased expression of IGFBP4 mRNA

NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473

G

insulin-like growth factor binding protein 7

decreases expression

EXP

nefazodone results in decreased expression of IGFBP7 mRNA

NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620

G

immunoglobulin superfamily, member 11

increases expression

EXP

nefazodone results in increased expression of IGSF11 mRNA

NCBI chr11:75,238,706...75,389,748
Ensembl chr11:75,236,545...75,390,425

G

immunoglobulin superfamily, member 5

decreases expression

EXP

nefazodone results in decreased expression of IGSF5 mRNA

NCBI chr11:35,686,513...35,729,396
Ensembl chr11:49,156,341...49,210,603

G

interferon gamma induced GTPase

decreases expression

EXP

nefazodone results in decreased expression of IGTP mRNA

NCBI chr10:42,875,047...42,882,866
Ensembl chr10:42,876,790...42,882,858

G

interleukin 13 receptor subunit alpha 1

increases expression

EXP

nefazodone results in increased expression of IL13RA1 mRNA

NCBI chr X:120,213,670...120,294,777
Ensembl chr X:120,214,075...120,274,461

G

interleukin 17 receptor A

decreases expression

EXP

nefazodone results in decreased expression of IL17RA mRNA

NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:155,339,400...155,362,382

G

interleukin 1 alpha

multiple interactions
decreases expression

EXP
ISO

[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone
nefazodone results in decreased expression of IL1A mRNA

PMID:19362101 PMID:32816093

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

decreases expression

ISO

nefazodone results in decreased expression of IL1B mRNA

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 24

increases expression

ISO

nefazodone results in increased expression of IL24 mRNA

NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760

G

interleukin 33

decreases expression

EXP

nefazodone results in decreased expression of IL33 mRNA

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901

G

IMP U3 small nucleolar ribonucleoprotein 3

increases expression

EXP

nefazodone results in increased expression of IMP3 mRNA

NCBI chr 8:66,235,498...66,236,386

G

IMP U3 small nucleolar ribonucleoprotein 4

increases expression

EXP

nefazodone results in increased expression of IMP4 mRNA

NCBI chr 9:44,150,029...44,155,167
Ensembl chr 9:44,150,337...44,157,751

G

inosine monophosphate dehydrogenase 2

increases expression

EXP

nefazodone results in increased expression of IMPDH2 mRNA

NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873

G

inhibin subunit beta A

decreases expression

EXP

nefazodone results in decreased expression of INHBA mRNA

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

inhibin subunit beta C

decreases expression

EXP

nefazodone results in decreased expression of INHBC mRNA

NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:65,069,451...65,082,919

G

indolethylamine N-methyltransferase

increases expression

EXP

nefazodone results in increased expression of INMT mRNA

NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755

G

insulin induced gene 1

decreases expression

EXP

nefazodone results in decreased expression of INSIG1 mRNA

NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778

G

insulin induced gene 2

increases expression

EXP

nefazodone results in increased expression of INSIG2 mRNA

NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658

G

inositol polyphosphate multikinase

decreases expression

EXP

nefazodone results in decreased expression of IPMK mRNA

NCBI chr20:17,216,151...17,250,826
Ensembl chr20:17,216,151...17,250,757

G

importin 4

increases expression

EXP

nefazodone results in increased expression of IPO4 mRNA

NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241

G

importin 5

increases expression

EXP

nefazodone results in increased expression of IPO5 mRNA

NCBI chr15:104,397,626...104,447,985
Ensembl chr15:104,397,276...104,447,985

G

importin 7

increases expression

EXP

nefazodone results in increased expression of IPO7 mRNA

NCBI chr 1:173,497,472...173,537,707
Ensembl chr 1:173,497,503...173,536,778

G

interleukin-1 receptor-associated kinase 1

increases expression

EXP

nefazodone results in increased expression of IRAK1 mRNA

NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825

G

iron responsive element binding protein 2

increases expression

EXP

nefazodone results in increased expression of IREB2 mRNA

NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520

G

interferon regulatory factor 6

decreases expression

EXP

nefazodone results in decreased expression of IRF6 mRNA

NCBI chr13:107,200,876...107,220,083
Ensembl chr13:107,200,731...107,220,049

G

immunity-related GTPase M

decreases expression

EXP

nefazodone results in decreased expression of IRGM mRNA

NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228

G

isochorismatase domain containing 1

increases expression

EXP

nefazodone results in increased expression of ISOC1 mRNA

NCBI chr18:54,356,757...54,377,170
Ensembl chr18:54,356,734...54,377,170

G

inter-alpha trypsin inhibitor, heavy chain 1

decreases expression

EXP

nefazodone results in decreased expression of ITIH1 mRNA

NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853

G

inter-alpha-trypsin inhibitor heavy chain 2

decreases expression

EXP

nefazodone results in decreased expression of ITIH2 mRNA

NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547

G

isovaleryl-CoA dehydrogenase

decreases expression

EXP

nefazodone results in decreased expression of IVD mRNA

NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160

G

iodotyrosine deiodinase

decreases expression

EXP

nefazodone results in decreased expression of IYD mRNA

NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386

G

jade family PHD finger 1

increases expression

EXP

nefazodone results in increased expression of JADE1 mRNA

NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:126,471,124...126,524,252

G

jagunal homolog 1

increases expression

EXP

nefazodone results in increased expression of JAGN1 mRNA

NCBI chr 4:148,147,213...148,151,915
Ensembl chr 4:148,147,229...148,151,915

G

jumonji domain containing 1C

decreases expression

EXP

nefazodone results in decreased expression of JMJD1C mRNA

NCBI chr20:21,330,990...21,508,580
Ensembl chr20:21,330,990...21,461,916

G

Josephin domain containing 1

increases expression

EXP

nefazodone results in increased expression of JOSD1 mRNA

NCBI chr 7:113,110,709...113,124,632
Ensembl chr 7:113,110,717...113,124,632

G

Josephin domain containing 2

increases expression

EXP

nefazodone results in increased expression of JOSD2 mRNA

NCBI chr 1:104,097,382...104,101,271
Ensembl chr 1:104,097,376...104,101,277

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression
increases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of JUN mRNA
nefazodone results in increased expression of JUN mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUN mRNA

PMID:24136188 PMID:27288927 PMID:32152650

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

JunD proto-oncogene, AP-1 transcription factor subunit

decreases expression
increases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of JUND mRNA
nefazodone results in increased expression of JUND mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUND mRNA

PMID:24136188 PMID:32152650

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148

G

junction plakoglobin

decreases expression

EXP

nefazodone results in decreased expression of JUP mRNA

NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429

G

KAT8 regulatory NSL complex subunit 1

decreases expression

EXP

nefazodone results in decreased expression of KANSL1 mRNA

NCBI chr10:89,237,667...89,368,735
Ensembl chr10:89,737,637...89,868,620

G

KAT8 regulatory NSL complex subunit 2

increases expression

EXP

nefazodone results in increased expression of KANSL2 mRNA

NCBI chr 7:129,669,031...129,685,750
Ensembl chr 7:131,548,062...131,564,753

G

potassium channel modulatory factor 1

increases expression

EXP

nefazodone results in increased expression of KCMF1 mRNA

NCBI chr 4:106,447,974...106,508,359
Ensembl chr 4:106,447,981...106,508,359

G

potassium voltage-gated channel subfamily H member 2

decreases activity
multiple interactions
affects activity

ISO

nefazodone results in decreased activity of KCNH2 protein
nefazodone binds to and results in decreased activity of KCNH2 protein
nefazodone affects the activity of KCNH2 protein

PMID:24052561 PMID:24374264 PMID:26821276 PMID:28551711

NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421

G

potassium inwardly-rectifying channel, subfamily J, member 3

multiple interactions

ISO

nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]

NCBI chr 3:60,353,990...60,518,110
Ensembl chr 3:60,354,146...60,518,104

G

potassium inwardly-rectifying channel, subfamily J, member 5

multiple interactions

ISO

nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]

NCBI chr 8:38,981,598...39,011,197
Ensembl chr 8:38,983,034...39,011,101

G

potassium inwardly-rectifying channel, subfamily J, member 6

multiple interactions

ISO

nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]

NCBI chr11:47,531,312...47,778,348
Ensembl chr11:47,531,312...47,778,348

G

potassium channel tetramerization domain containing 5

increases expression

EXP

nefazodone results in increased expression of KCTD5 mRNA

NCBI chr10:13,583,781...13,609,762
Ensembl chr10:13,583,781...13,610,062

G

potassium channel tetramerization domain containing 9

increases expression

EXP

nefazodone results in increased expression of KCTD9 mRNA

NCBI chr15:46,117,211...46,145,258
Ensembl chr15:46,117,874...46,145,266

G

lysine demethylase 5B

decreases expression

EXP

nefazodone results in decreased expression of KDM5B mRNA

NCBI chr13:48,554,367...48,625,721
Ensembl chr13:48,554,420...48,626,423

G

Kelch-like ECH-associated protein 1

increases expression

EXP

nefazodone results in increased expression of KEAP1 mRNA

NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042

G

KLF transcription factor 15

increases expression

EXP

nefazodone results in increased expression of KLF15 mRNA

NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373

G

kelch domain containing 2

increases expression

EXP

nefazodone results in increased expression of KLHDC2 mRNA

NCBI chr 6:93,512,981...93,552,809
Ensembl chr 6:93,513,017...93,577,762

G

lysine methyltransferase 2E

decreases expression

EXP

nefazodone results in decreased expression of KMT2E mRNA

NCBI chr 4:12,550,570...12,655,329
Ensembl chr 4:12,550,570...12,619,721

G

kininogen 1

decreases expression

EXP

nefazodone results in decreased expression of KNG1 mRNA

NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148

G

kininogen 2

decreases expression

EXP

nefazodone results in decreased expression of KNG2 mRNA

NCBI chr11:91,418,470...91,440,841
Ensembl chr11:91,414,207...91,441,259

G

karyopherin subunit alpha 1

increases expression

EXP

nefazodone results in increased expression of KPNA1 mRNA

NCBI chr11:78,221,165...78,279,778
Ensembl chr11:78,222,884...78,267,067

G

keratin 18

increases expression

EXP

nefazodone results in increased expression of KRT18 mRNA

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848

G

keratin 8

increases expression

EXP

nefazodone results in increased expression of KRT8 mRNA

NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403

G

KxDL motif containing 1

increases expression

EXP

nefazodone results in increased expression of KXD1 mRNA

NCBI chr16:18,929,316...18,950,239
Ensembl chr16:18,936,356...18,950,237

G

kynurenine aminotransferase 1

increases expression

EXP

nefazodone results in increased expression of KYAT1 mRNA

NCBI chr 3:33,857,407...33,891,153
Ensembl chr 3:33,857,743...33,890,642

G

kynureninase

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of KYNU mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of KYNU mRNA

PMID:24136188 PMID:33819548

NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014

G

L3MBTL histone methyl-lysine binding protein 2

increases expression

EXP

nefazodone results in increased expression of L3MBTL2 mRNA

NCBI chr 7:115,066,427...115,087,625
Ensembl chr 7:115,066,486...115,087,598

G

lactamase, beta 2

increases expression

EXP

nefazodone results in increased expression of LACTB2 mRNA

NCBI chr 5:10,352,165...10,374,928
Ensembl chr 5:10,352,154...10,379,255

G

laminin subunit alpha 3

increases expression

EXP

nefazodone results in increased expression of LAMA3 mRNA

NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

increases expression

EXP

nefazodone results in increased expression of LAMTOR3 mRNA

NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:229,084,858...229,099,383

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

increases expression

EXP

nefazodone results in increased expression of LAMTOR4 mRNA

NCBI chr12:22,372,269...22,376,090
Ensembl chr12:22,372,269...22,376,090

G

LanC like glutathione S-transferase 1

increases expression

EXP

nefazodone results in increased expression of LANCL1 mRNA

NCBI chr 9:75,968,284...75,998,397
Ensembl chr 9:75,968,286...76,003,475

G

leucine aminopeptidase 3

decreases expression

EXP

nefazodone results in decreased expression of LAP3 mRNA

NCBI chr14:69,820,907...69,839,891
Ensembl chr14:69,820,908...69,839,891

G

lysosomal protein transmembrane 4 alpha

increases expression

EXP

nefazodone results in increased expression of LAPTM4A mRNA

NCBI chr 6:37,438,503...37,456,238
Ensembl chr 6:37,438,121...37,456,223

G

lipopolysaccharide binding protein

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of LBP mRNA

NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518

G

leucine carboxyl methyltransferase 1

decreases expression

EXP

nefazodone results in decreased expression of LCMT1 mRNA

NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:187,327,706...187,391,516

G

low density lipoprotein receptor

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of LDLR mRNA

NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675

G

leukocyte cell-derived chemotaxin 2

decreases expression

EXP

nefazodone results in decreased expression of LECT2 mRNA

NCBI chr17:8,050,034...8,056,256
Ensembl chr17:8,050,034...8,056,256

G

leptin receptor overlapping transcript-like 1

increases expression

EXP

nefazodone results in increased expression of LEPROTL1 mRNA

NCBI chr16:64,744,148...64,756,776
Ensembl chr16:64,743,717...64,756,776

G

galectin 5

decreases expression

EXP

nefazodone results in decreased expression of LGALS5 mRNA

NCBI chr10:64,351,976...64,355,137
Ensembl chr10:64,351,964...64,355,180

G

galectin 8

increases expression

EXP

nefazodone results in increased expression of LGALS8 mRNA

NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482

G

galectin 9

decreases expression

EXP

nefazodone results in decreased expression of LGALS9 mRNA

NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070

G

galectin-like

decreases expression

EXP

nefazodone results in decreased expression of LGALSL mRNA

NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487

G

LIM zinc finger domain containing 2

decreases expression

EXP

nefazodone results in decreased expression of LIMS2 mRNA

NCBI chr18:23,828,164...23,866,363
Ensembl chr18:23,837,686...23,867,086

G

lin-37 DREAM MuvB core complex component

increases expression

EXP

nefazodone results in increased expression of LIN37 mRNA

NCBI chr 1:94,936,512...94,940,444
Ensembl chr 1:94,936,512...94,940,444

G

lipase A, lysosomal acid type

increases expression

EXP

nefazodone results in increased expression of LIPA mRNA

NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740

G

lipase C, hepatic type

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of LIPC mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of LIPC mRNA

PMID:24136188 PMID:33819548

NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285

G

LMBR1 domain containing 1

increases expression

EXP

nefazodone results in increased expression of LMBRD1 mRNA

NCBI chr 9:34,592,723...34,674,425
Ensembl chr 9:34,577,616...34,674,428

G

lamin A/C

increases expression

EXP

nefazodone results in increased expression of LMNA mRNA

NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072

G

lysyl oxidase

decreases expression

EXP

nefazodone results in decreased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810

G

lipin 1

decreases expression

EXP

nefazodone results in decreased expression of LPIN1 mRNA

NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991

G

lecithin retinol acyltransferase

decreases expression

EXP

nefazodone results in decreased expression of LRAT mRNA

NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148

G

LDL receptor related protein 1

decreases expression

EXP

nefazodone results in decreased expression of LRP1 mRNA

NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196

G

LDL receptor related protein 3

decreases expression

EXP

nefazodone results in decreased expression of LRP3 mRNA

NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057

G

LDL receptor related protein 5

decreases expression

EXP

nefazodone results in decreased expression of LRP5 mRNA

NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822

G

LDL receptor related protein 6

decreases expression

EXP

nefazodone results in decreased expression of LRP6 mRNA

NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716

G

leucine rich repeat containing 59

increases expression

EXP

nefazodone results in increased expression of LRRC59 mRNA

NCBI chr10:80,069,162...80,083,820
Ensembl chr10:80,069,120...80,084,079

G

leucine rich repeat containing 8 VRAC subunit B

decreases expression

EXP

nefazodone results in decreased expression of LRRC8B mRNA

NCBI chr14:4,655,273...4,721,648
Ensembl chr14:4,655,273...4,721,076

G

LSM10, U7 small nuclear RNA associated

increases expression

EXP

nefazodone results in increased expression of LSM10 mRNA

NCBI chr 5:143,649,817...143,660,391
Ensembl chr 5:143,615,360...143,663,986

G

leukotriene A4 hydrolase

decreases expression

EXP

nefazodone results in decreased expression of LTA4H mRNA

NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641

G

lymphotoxin beta receptor

increases expression

EXP

nefazodone results in increased expression of LTBR mRNA

NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296

G

LUC7 pre-mRNA splicing factor like 2

decreases expression

EXP

nefazodone results in decreased expression of LUC7L2 mRNA

NCBI chr 4:68,251,435...68,314,861
Ensembl chr 4:68,271,414...68,314,837

G

lymphocyte antigen 96

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of LY96 mRNA

NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:7,365,557...7,395,816

G

lysophospholipase 1

decreases expression

EXP

nefazodone results in decreased expression of LYPLA1 mRNA

NCBI chr 5:19,477,408...19,506,568
Ensembl chr 5:19,477,409...19,506,522

G

lysophospholipase-like 1

increases expression

EXP

nefazodone results in increased expression of LYPLAL1 mRNA

NCBI chr13:100,158,060...100,189,339
Ensembl chr13:100,158,060...100,189,503

G

lymphatic vessel endothelial hyaluronan receptor 1

decreases expression

EXP

nefazodone results in decreased expression of LYVE1 mRNA

NCBI chr 1:174,393,387...174,410,977

G

macoilin 1

increases expression

EXP

nefazodone results in increased expression of MACO1 mRNA

NCBI chr 5:152,296,107...152,358,684
Ensembl chr 5:152,296,558...152,358,684

G

mono-ADP ribosylhydrolase 1

decreases expression

EXP

nefazodone results in decreased expression of MACROD1 mRNA

NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348

G

MAF bZIP transcription factor

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MAF mRNA

NCBI chr19:60,259,200...60,622,145
Ensembl chr19:60,269,541...60,621,378

G

MAF bZIP transcription factor B

decreases expression

EXP

nefazodone results in decreased expression of MAFB mRNA

NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975

G

MAF bZIP transcription factor F

increases expression
multiple interactions

ISO

nefazodone results in increased expression of MAFF mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147

G

MAF bZIP transcription factor G

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFG mRNA
nefazodone results in increased expression of MAFG mRNA

NCBI chr10:106,401,633...106,410,159

G

MAF bZIP transcription factor K

increases expression
multiple interactions

ISO

nefazodone results in increased expression of MAFK mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFK mRNA

NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192

G

mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1

increases expression

EXP

nefazodone results in increased expression of MAGMAS-PS1 mRNA

NCBI chr10:88,602,379...88,602,899

G

mago homolog, exon junction complex subunit

increases expression

EXP

nefazodone results in increased expression of MAGOH mRNA

NCBI chr 5:127,868,044...127,875,423
Ensembl chr 5:127,868,055...127,875,384

G

mal, T-cell differentiation protein 2

increases expression

EXP

nefazodone results in increased expression of MAL2 mRNA

NCBI chr 7:87,790,239...87,823,219
Ensembl chr 7:87,790,239...87,850,403

G

mitochondrial assembly of ribosomal large subunit 1

increases expression

EXP

nefazodone results in increased expression of MALSU1 mRNA

NCBI chr 4:79,381,963...79,390,786
Ensembl chr 4:79,374,393...79,411,608

G

monoamine oxidase A

increases expression

EXP

nefazodone results in increased expression of MAOA mRNA

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631

G

microtubule-associated protein 1 light chain 3 beta

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of MAP1LC3B mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP1LC3B mRNA; nefazodone results in increased expression of and results in increased lipidation of MAP1LC3B protein

PMID:24136188 PMID:32152650 PMID:33609687

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358

G

mitogen activated protein kinase kinase 1

increases expression

EXP

nefazodone results in increased expression of MAP2K1 mRNA

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184

G

mitogen activated protein kinase kinase 2

increases expression

EXP

nefazodone results in increased expression of MAP2K2 mRNA

NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940

G

mitogen activated protein kinase kinase 3

increases expression

EXP

nefazodone results in increased expression of MAP2K3 mRNA

NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004

G

mitogen-activated protein kinase kinase 6

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MAP2K6 mRNA

NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721

G

mitogen activated protein kinase 1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of MAPK1 mRNA
nefazodone results in increased phosphorylation of and results in increased activity of MAPK1 protein

PMID:24136188 PMID:27613715

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

ISO

nefazodone results in increased phosphorylation of and results in increased activity of MAPK3 protein

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

MAPK activated protein kinase 2

decreases expression

EXP

nefazodone results in decreased expression of MAPKAPK2 mRNA

NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326

G

MAPK activated protein kinase 3

increases expression
multiple interactions

ISO

nefazodone results in increased expression of MAPKAPK3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAPKAPK3 mRNA

NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228

G

membrane associated ring-CH-type finger 5

increases expression

EXP

nefazodone results in increased expression of MARCHF5 mRNA

NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:244,343,630...244,366,462

G

membrane associated ring-CH-type finger 6

increases expression

EXP

nefazodone results in increased expression of MARCHF6 mRNA

NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:84,166,570...84,243,792

G

MARCKS-like 1

decreases expression

EXP

nefazodone results in decreased expression of MARCKSL1 mRNA

NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417

G

MBL associated serine protease 1

decreases expression

EXP

nefazodone results in decreased expression of MASP1 mRNA

NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470

G

mannose binding lectin 1

decreases expression

EXP

nefazodone results in decreased expression of MBL1 mRNA

NCBI chr16:17,063,232...17,069,271
Ensembl chr16:17,060,703...17,069,271

G

mannose binding lectin 2

decreases expression

EXP

nefazodone results in decreased expression of MBL2 mRNA

NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546

G

mbt domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of MBTD1 mRNA

NCBI chr10:79,336,041...79,392,315
Ensembl chr10:79,335,235...79,392,315

G

methylmalonyl CoA epimerase

decreases expression

EXP

nefazodone results in decreased expression of MCEE mRNA

NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:127,376,298...127,400,367

G

mucolipin TRP cation channel 1

increases expression

EXP

nefazodone results in increased expression of MCOLN1 mRNA

NCBI chr12:6,357,851...6,372,151
Ensembl chr12:6,357,807...6,372,151

G

MDM2 proto-oncogene

increases expression

EXP

nefazodone results in increased expression of MDM2 mRNA

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

malic enzyme 1

increases expression

EXP

nefazodone results in increased expression of ME1 mRNA

NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275

G

mitochondrial trans-2-enoyl-CoA reductase

increases expression

EXP

nefazodone results in increased expression of MECR mRNA

NCBI chr 5:149,313,765...149,339,964
Ensembl chr 5:149,313,774...149,342,825

G

mediator complex subunit 31

increases expression

EXP

nefazodone results in increased expression of MED31 mRNA

NCBI chr10:57,335,507...57,338,889
Ensembl chr10:57,335,507...57,338,889

G

MET proto-oncogene, receptor tyrosine kinase

increases expression

ISO

nefazodone results in increased expression of MET mRNA

NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821

G

methionyl aminopeptidase 2

increases expression

EXP

nefazodone results in increased expression of METAP2 mRNA

NCBI chr 7:30,299,433...30,327,477
Ensembl chr 7:30,299,433...30,327,521

G

methyltransferase 5, N6-adenosine

increases expression

EXP

nefazodone results in increased expression of METTL5 mRNA

NCBI chr 3:75,033,605...75,046,359
Ensembl chr 3:75,026,861...75,045,831

G

major facilitator superfamily domain containing 1

increases expression

EXP

nefazodone results in increased expression of MFSD1 mRNA

NCBI chr 2:154,156,167...154,176,209
Ensembl chr 2:154,156,166...154,177,086

G

major facilitator superfamily domain containing 4B1

increases expression

EXP

nefazodone results in increased expression of MFSD4B1 mRNA

NCBI chr20:43,436,857...43,450,064
Ensembl chr20:44,991,384...45,006,161

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

decreases expression

EXP

nefazodone results in decreased expression of MGAT4B mRNA

NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309

G

monoglyceride lipase

increases expression

EXP

nefazodone results in increased expression of MGLL mRNA

NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440

G

microsomal glutathione S-transferase 2

increases expression
decreases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of MGST2 mRNA
nefazodone results in decreased expression of MGST2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of MGST2 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MGST2 mRNA

PMID:24136188 PMID:32152650 PMID:33819548

NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661

G

microsomal glutathione S-transferase 3

decreases expression

EXP

nefazodone results in decreased expression of MGST3 mRNA

NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575

G

MID1 interacting protein 1

decreases expression

EXP

nefazodone results in decreased expression of MID1IP1 mRNA

NCBI chr X:14,733,539...14,735,859
Ensembl chr X:14,732,830...14,739,079

G

macrophage migration inhibitory factor

increases expression

EXP

nefazodone results in increased expression of MIF mRNA

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

MINDY lysine 48 deubiquitinase 3

decreases expression

EXP

nefazodone results in decreased expression of MINDY3 mRNA

NCBI chr17:80,454,404...80,532,999
Ensembl chr17:80,454,405...80,532,960

G

myo-inositol oxygenase

increases expression

EXP

nefazodone results in increased expression of MIOX mRNA

NCBI chr 7:122,284,660...122,287,158
Ensembl chr 7:122,284,660...122,287,157

G

mitochondrial matrix import factor 23

increases expression

EXP

nefazodone results in increased expression of MIX23 mRNA

NCBI chr11:78,166,038...78,186,323
Ensembl chr11:78,166,038...78,186,323

G

MAPK interacting serine/threonine kinase 2

decreases expression

EXP

nefazodone results in decreased expression of MKNK2 mRNA

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529

G

malectin

increases expression

EXP

nefazodone results in increased expression of MLEC mRNA

NCBI chr12:41,458,234...41,468,710
Ensembl chr12:47,118,855...47,130,064

G

mixed lineage kinase domain like pseudokinase

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MLKL mRNA
nefazodone results in increased expression of MLKL mRNA

NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858

G

MAX dimerization protein MLX

increases expression

EXP

nefazodone results in increased expression of MLX mRNA

NCBI chr10:86,519,517...86,524,607
Ensembl chr10:86,519,864...86,524,772

G

MLX interacting protein-like

decreases expression

EXP

nefazodone results in decreased expression of MLXIPL mRNA

NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660

G

malonyl-CoA decarboxylase

increases expression

EXP

nefazodone results in increased expression of MLYCD mRNA

NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446

G

metabolism of cobalamin associated D

increases expression

EXP

nefazodone results in increased expression of MMADHC mRNA

NCBI chr 3:55,117,832...55,135,735
Ensembl chr 3:55,117,833...55,135,851

G

membrane magnesium transporter 1

increases expression

EXP

nefazodone results in increased expression of MMGT1 mRNA

NCBI chr X:139,445,834...139,458,169
Ensembl chr X:139,445,834...139,458,169

G

methylmalonyl-CoA mutase

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of MMUT mRNA

NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342

G

molybdenum cofactor synthesis 2

increases expression

EXP

nefazodone results in increased expression of MOCS2 mRNA

NCBI chr 2:48,237,655...48,249,394
Ensembl chr 2:48,237,655...48,249,394

G

mortality factor 4 like 2

increases expression

EXP

nefazodone results in increased expression of MORF4L2 mRNA

NCBI chr X:104,874,850...104,885,946
Ensembl chr X:104,852,693...104,892,855

G

motile sperm domain containing 3

decreases expression

EXP

nefazodone results in decreased expression of MOSPD3 mRNA

NCBI chr12:24,728,012...24,737,078
Ensembl chr12:24,732,008...24,736,244

G

mitochondrial pyruvate carrier 1

decreases expression

EXP

nefazodone results in decreased expression of MPC1 mRNA

NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064

G

mitochondrial pyruvate carrier 2

increases expression

EXP

nefazodone results in increased expression of MPC2 mRNA

NCBI chr13:80,261,143...80,280,668
Ensembl chr13:80,259,727...80,280,668

G

MAGUK p55 scaffold protein 1

decreases expression

EXP

nefazodone results in decreased expression of MPP1 mRNA

G

mercaptopyruvate sulfurtransferase

decreases expression

EXP

nefazodone results in decreased expression of MPST mRNA

NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:111,835,587...111,843,650

G

methylthioribose-1-phosphate isomerase 1

increases expression

EXP

nefazodone results in increased expression of MRI1 mRNA

NCBI chr19:40,812,114...40,819,846
Ensembl chr19:40,812,094...40,822,607

G

maestro

decreases expression

EXP

nefazodone results in decreased expression of MRO mRNA

NCBI chr18:69,723,764...69,742,815
Ensembl chr18:69,725,798...69,743,031

G

mitochondrial ribosomal protein L14

increases expression

EXP

nefazodone results in increased expression of MRPL14 mRNA

NCBI chr 9:22,800,286...22,812,711
Ensembl chr 9:22,795,744...22,812,855

G

mitochondrial ribosomal protein L17

increases expression

EXP

nefazodone results in increased expression of MRPL17 mRNA

NCBI chr 1:169,574,010...169,575,699
Ensembl chr 1:169,574,010...169,575,818

G

mitochondrial ribosomal protein L18

increases expression

EXP

nefazodone results in increased expression of MRPL18 mRNA

NCBI chr 1:50,384,951...50,389,769
Ensembl chr 1:50,384,367...50,389,763

G

mitochondrial ribosomal protein L19

increases expression

EXP

nefazodone results in increased expression of MRPL19 mRNA

NCBI chr 4:116,079,654...116,083,883
Ensembl chr 4:116,079,654...116,083,883

G

mitochondrial ribosomal protein L20

increases expression

EXP

nefazodone results in increased expression of MRPL20 mRNA

NCBI chr 5:171,690,664...171,695,728
Ensembl chr 5:171,691,198...171,695,728

G

mitochondrial ribosomal protein L22

increases expression

EXP

nefazodone results in increased expression of MRPL22 mRNA

NCBI chr10:42,843,165...42,856,243
Ensembl chr10:42,843,222...42,856,227

G

mitochondrial ribosomal protein L23

increases expression

EXP

nefazodone results in increased expression of MRPL23 mRNA

NCBI chr 1:207,116,930...207,124,702
Ensembl chr 1:207,116,462...207,124,699

G

mitochondrial ribosomal protein L24

increases expression

EXP

nefazodone results in increased expression of MRPL24 mRNA

NCBI chr 2:175,680,872...175,687,107
Ensembl chr 2:175,681,070...175,688,660

G

mitochondrial ribosomal protein L34

increases expression

EXP

nefazodone results in increased expression of MRPL34 mRNA

NCBI chr16:18,186,447...18,187,182
Ensembl chr16:18,185,306...18,187,181

G

mitochondrial ribosomal protein L36

increases expression

EXP

nefazodone results in increased expression of MRPL36 mRNA

NCBI chr 1:31,794,025...31,797,446
Ensembl chr 1:31,790,887...31,797,808

G

mitochondrial ribosomal protein L49

increases expression

EXP

nefazodone results in increased expression of MRPL49 mRNA

NCBI chr 1:212,775,357...212,779,364
Ensembl chr 1:212,775,357...212,779,888

G

mitochondrial ribosomal protein L50

increases expression

EXP

nefazodone results in increased expression of MRPL50 mRNA

NCBI chr 5:68,662,933...68,668,087
Ensembl chr 5:68,662,939...68,669,748

G

mitochondrial ribosomal protein L52

increases expression

EXP

nefazodone results in increased expression of MRPL52 mRNA

NCBI chr15:31,852,927...31,856,160
Ensembl chr15:31,852,760...31,856,162

G

mitochondrial ribosomal protein L55

increases expression

EXP

nefazodone results in increased expression of MRPL55 mRNA

NCBI chr10:44,488,252...44,491,401
Ensembl chr10:44,488,244...44,491,401

G

mitochondrial ribosomal protein S18B

increases expression

EXP

nefazodone results in increased expression of MRPS18B mRNA

NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065

G

mitochondrial ribosomal protein S18C

increases expression

EXP

nefazodone results in increased expression of MRPS18C mRNA

NCBI chr14:9,116,688...9,122,943

G

mitochondrial ribosomal protein S30

increases expression

EXP

nefazodone results in increased expression of MRPS30 mRNA

NCBI chr 2:52,189,049...52,196,136
Ensembl chr 2:52,189,058...52,195,904

G

mitochondrial ribosomal protein S33

increases expression

EXP

nefazodone results in increased expression of MRPS33 mRNA

NCBI chr 4:69,563,501...69,572,317
Ensembl chr 4:69,563,503...69,572,177

G

mitochondrial ribosomal protein S34

increases expression

EXP

nefazodone results in increased expression of MRPS34 mRNA

NCBI chr10:14,420,543...14,421,674
Ensembl chr10:14,408,136...14,421,771

G

mitochondrial ribosomal protein S9

increases expression

EXP

nefazodone results in increased expression of MRPS9 mRNA

NCBI chr 9:52,605,678...52,664,499
Ensembl chr 9:52,605,678...52,664,499

G

MRT4 homolog, ribosome maturation factor

increases expression

EXP

nefazodone results in increased expression of MRTO4 mRNA

NCBI chr 5:151,601,780...151,608,533
Ensembl chr 5:156,884,985...156,891,738

G

methionine sulfoxide reductase B2

increases expression

EXP

nefazodone results in increased expression of MSRB2 mRNA

NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391

G

mitochondrially encoded ATP synthase membrane subunit 8

decreases expression

ISO

nefazodone results in decreased expression of ATP8 mRNA

NCBI chr MT:7,758...7,961
Ensembl chr MT:7,743...7,946

G

mitochondrially encoded cytochrome c oxidase I

decreases expression

ISO

nefazodone results in decreased expression of COX1 mRNA

NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

decreases expression

ISO

nefazodone results in decreased expression of ND5 mRNA

NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553

G

metallothionein 1A

increases expression

EXP

nefazodone results in increased expression of MT1A mRNA

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

mitochondrial amidoxime reducing component 1

decreases expression

EXP

nefazodone results in decreased expression of MTARC1 mRNA

NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252

G

mitochondrial transcription termination factor 3

increases expression

EXP

nefazodone results in increased expression of MTERF3 mRNA

NCBI chr 7:65,711,654...65,729,926
Ensembl chr 7:65,711,662...65,729,895

G

methenyltetrahydrofolate synthetase

increases expression

EXP

nefazodone results in increased expression of MTHFS mRNA

NCBI chr 8:98,609,410...98,681,901
Ensembl chr 8:98,609,399...98,752,036

G

myotubularin related protein 4

increases expression

EXP

nefazodone results in increased expression of MTMR4 mRNA

NCBI chr10:72,890,665...72,913,598
Ensembl chr10:72,889,827...72,913,598

G

myotrophin

increases expression

EXP

nefazodone results in increased expression of MTPN mRNA

NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924

G

MTSS I-BAR domain containing 1

increases expression

EXP

nefazodone results in increased expression of MTSS1 mRNA

NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303

G

microsomal triglyceride transfer protein

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of MTTP mRNA

NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650

G

murinoglobulin 1

decreases expression

EXP

nefazodone results in decreased expression of MUG1 mRNA

NCBI chr 4:156,748,351...156,802,132

G

murinoglobulin 2

decreases expression

EXP

nefazodone results in decreased expression of PZP mRNA

NCBI chr 4:156,836,140...156,908,972

G

mevalonate kinase

decreases expression

EXP

nefazodone results in decreased expression of MVK mRNA

NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503

G

MYB binding protein 1a

increases expression

EXP

nefazodone results in increased expression of MYBBP1A mRNA

NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,555,452...57,566,041

G

myosin, heavy chain 9

decreases expression

EXP

nefazodone results in decreased expression of MYH9 mRNA

NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963

G

myosin ID

decreases expression

EXP

nefazodone results in decreased expression of MYO1D mRNA

NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,975,122...66,263,958

G

myosin IG

increases expression

EXP

nefazodone results in increased expression of MYO1G mRNA

NCBI chr14:85,600,619...85,615,760
Ensembl chr14:85,600,619...85,615,760

G

myogenesis regulating glycosidase

decreases expression

EXP

nefazodone results in decreased expression of MYORG mRNA

NCBI chr 5:61,452,956...61,460,500
Ensembl chr 5:61,432,418...61,460,581

G

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

increases expression

EXP

nefazodone results in increased expression of NAA15 mRNA

NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619

G

N(alpha)-acetyltransferase 20, NatB catalytic subunit

increases expression

EXP

nefazodone results in increased expression of NAA20 mRNA

NCBI chr 3:153,775,351...153,790,129
Ensembl chr 3:153,775,338...153,790,916

G

N(alpha)-acetyltransferase 50, NatE catalytic subunit

increases expression

EXP

nefazodone results in increased expression of NAA50 mRNA

NCBI chr11:70,044,281...70,066,754
Ensembl chr11:70,044,281...70,066,754

G

Ngfi-A binding protein 1

increases expression

EXP

nefazodone results in increased expression of NAB1 mRNA

NCBI chr 9:56,545,547...56,585,045
Ensembl chr 9:56,545,729...56,614,210

G

NEDD8 activating enzyme E1 subunit 1

increases expression

EXP

nefazodone results in increased expression of NAE1 mRNA

NCBI chr19:452,462...478,591
Ensembl chr19:452,432...478,831

G

alpha-N-acetylgalactosaminidase

decreases expression

EXP

nefazodone results in decreased expression of NAGA mRNA

NCBI chr 7:115,726,438...115,735,494
Ensembl chr 7:115,726,624...115,736,828

G

nicotinamide phosphoribosyltransferase

increases expression

EXP

nefazodone results in increased expression of NAMPT mRNA

NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544

G

nucleosome assembly protein 1-like 1

increases expression

EXP

nefazodone results in increased expression of NAP1L1 mRNA

NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104

G

NSF attachment protein gamma

increases expression

EXP

nefazodone results in increased expression of NAPG mRNA

NCBI chr18:58,710,702...58,729,450
Ensembl chr18:58,708,655...58,729,450

G

asparaginyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of NARS1 mRNA

NCBI chr18:60,259,506...60,275,782
Ensembl chr18:60,259,516...60,275,782

G

N-acetyltransferase 8

increases expression

EXP

nefazodone results in increased expression of NAT8 mRNA

NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159

G

nuclear cap binding protein subunit 1

increases expression

EXP

nefazodone results in increased expression of NCBP1 mRNA

NCBI chr 5:65,211,632...65,244,532
Ensembl chr 5:65,211,358...65,244,665

G

NCK-associated protein 1

increases expression

EXP

nefazodone results in increased expression of NCKAP1 mRNA

NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797

G

nuclear receptor co-repressor 1

decreases expression

EXP

nefazodone results in decreased expression of NCOR1 mRNA

NCBI chr10:47,498,852...47,641,612
Ensembl chr10:47,498,852...47,640,350

G

Nedd4 family interacting protein 2

increases expression

EXP

nefazodone results in increased expression of NDFIP2 mRNA

NCBI chr15:88,394,548...88,500,881
Ensembl chr15:88,395,032...88,503,600

G

NDRG family member 2

decreases expression

EXP

nefazodone results in decreased expression of NDRG2 mRNA

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

NADH:ubiquinone oxidoreductase subunit A5

increases expression

EXP

nefazodone results in increased expression of NDUFA5 mRNA

NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235

G

NADH:ubiquinone oxidoreductase subunit AB1

increases expression

EXP

nefazodone results in increased expression of NDUFAB1 mRNA

NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:186,057,113...186,089,373

G

NADH:ubiquinone oxidoreductase complex assembly factor 3

increases expression

EXP

nefazodone results in increased expression of NDUFAF3 mRNA

NCBI chr 8:118,139,891...118,141,723
Ensembl chr 8:118,139,892...118,141,723

G

NADH:ubiquinone oxidoreductase complex assembly factor 4

increases expression

EXP

nefazodone results in increased expression of NDUFAF4 mRNA

NCBI chr 5:43,401,795...43,406,967

G

NADH:ubiquinone oxidoreductase subunit C2

increases expression

EXP

nefazodone results in increased expression of NDUFC2 mRNA

NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419

G

NADH:ubiquinone oxidoreductase subunit V3

decreases expression

EXP

nefazodone results in decreased expression of NDUFV3 mRNA

NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847
Ensembl chr20:48,468,224...48,488,847

G

nectin cell adhesion molecule 3

decreases expression

EXP

nefazodone results in decreased expression of NECTIN3 mRNA

NCBI chr11:67,825,296...67,931,999
Ensembl chr11:67,827,137...67,871,383

G

neuroepithelial cell transforming 1

decreases expression

EXP

nefazodone results in decreased expression of NET1 mRNA

NCBI chr17:71,251,145...71,280,345
Ensembl chr17:71,251,149...71,289,270

G

NFE2 like bZIP transcription factor 2

decreases expression

EXP

nefazodone results in decreased expression of NFE2L2 mRNA

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nuclear factor I/A

decreases expression

EXP

nefazodone results in decreased expression of NFIA mRNA

NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395

G

nuclear factor I/B

decreases expression

EXP

nefazodone results in decreased expression of NFIB mRNA

NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945

G

nuclear factor, interleukin 3 regulated

decreases expression

EXP

nefazodone results in decreased expression of NFIL3 mRNA

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826

G

NFKB inhibitor beta

increases expression

EXP

nefazodone results in increased expression of NFKBIB mRNA

NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366

G

NFU1 iron-sulfur cluster scaffold

increases expression

EXP

nefazodone results in increased expression of NFU1 mRNA

NCBI chr 4:121,016,316...121,036,925
Ensembl chr 4:121,016,393...121,037,493

G

nuclear transcription factor, X-box binding 1

increases expression

EXP

nefazodone results in increased expression of NFX1 mRNA

NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889

G

nuclear transcription factor, X-box binding-like 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of NFXL1 mRNA

NCBI chr14:35,980,058...36,021,478
Ensembl chr14:35,980,057...36,023,281

G

NHP2 ribonucleoprotein

increases expression

EXP

nefazodone results in increased expression of NHP2 mRNA

NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354

G

nucleolar protein interacting with the FHA domain of MKI67

increases expression

EXP

nefazodone results in increased expression of NIFK mRNA

NCBI chr13:29,393,303...29,403,387
Ensembl chr13:31,946,108...31,959,561

G

nipsnap homolog 3B

decreases expression

EXP

nefazodone results in decreased expression of NIPSNAP3A mRNA

NCBI chr 5:72,446,945...72,465,090
Ensembl chr 5:72,432,957...72,465,544

G

nitrilase 1

increases expression

EXP

nefazodone results in increased expression of NIT1 mRNA

NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770

G

N-myristoyltransferase 1

increases expression

EXP

nefazodone results in increased expression of NMT1 mRNA

NCBI chr10:88,488,918...88,525,496
Ensembl chr10:88,488,990...88,522,729

G

nicotinamide N-methyltransferase

decreases expression

EXP

nefazodone results in decreased expression of NNMT mRNA

NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174

G

Nodal modulator 1

increases expression

EXP

nefazodone results in increased expression of NOMO1 mRNA

NCBI chr 1:105,641,867...105,692,708
Ensembl chr 1:105,641,879...105,692,707

G

non-POU domain containing, octamer-binding

increases expression

EXP

nefazodone results in increased expression of NONO mRNA

NCBI chr X:70,594,116...70,611,976
Ensembl chr X:70,593,888...70,611,979

G

NOP16 nucleolar protein

increases expression

EXP

nefazodone results in increased expression of NOP16 mRNA

NCBI chr17:10,022,950...10,027,867
Ensembl chr17:10,028,034...10,033,038

G

NOP56 ribonucleoprotein

increases expression

EXP

nefazodone results in increased expression of NOP56 mRNA

NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959

G

notch receptor 2

decreases expression

EXP

nefazodone results in decreased expression of NOTCH2 mRNA

NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823

G

aminopeptidase-like 1

increases expression

EXP

nefazodone results in increased expression of NPEPL1 mRNA

NCBI chr 3:183,312,185...183,324,744
Ensembl chr 3:183,312,185...183,324,744

G

nephrocystin 1

increases expression

EXP

nefazodone results in increased expression of NPHP1 mRNA

NCBI chr 3:135,413,927...135,469,505
Ensembl chr 3:135,413,927...135,469,505

G

NPL4 homolog, ubiquitin recognition factor

increases expression

EXP

nefazodone results in increased expression of NPLOC4 mRNA

NCBI chr10:106,152,756...106,208,306
Ensembl chr10:106,153,173...106,208,264

G

nucleophosmin 1

increases expression

EXP

nefazodone results in increased expression of NPM1 mRNA

NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr X:18,245,740...18,256,024

G

NAD(P)H quinone dehydrogenase 1

increases expression

EXP

nefazodone results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

decreases expression

EXP

nefazodone results in decreased expression of NQO2 mRNA

NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662

G

nuclear receptor subfamily 1, group D, member 2

increases expression

EXP

nefazodone results in increased expression of NR1D2 mRNA

NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330

G

nuclear receptor subfamily 1, group H, member 2

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of NR1H2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of NR1H2 mRNA

PMID:24136188 PMID:33819548

NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863

G

nuclear receptor subfamily 1, group H, member 3

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of NR1H3 mRNA

NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532

G

nuclear receptor subfamily 1, group H, member 4

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of NR1H4 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1H4 mRNA

PMID:24136188 PMID:32152650

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389

G

nuclear receptor subfamily 1, group I, member 2

decreases expression

ISO

nefazodone results in decreased expression of NR1I2 mRNA

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

G

nuclear receptor subfamily 1, group I, member 3

increases expression
decreases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of NR1I3 mRNA
nefazodone results in decreased expression of NR1I3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1I3 mRNA

PMID:24136188 PMID:32152650

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370

G

nuclear receptor 2C2-associated protein

increases expression

EXP

nefazodone results in increased expression of NR2C2AP mRNA

NCBI chr16:19,322,395...19,324,912
Ensembl chr16:19,322,405...19,324,637

G

nuclear receptor subfamily 3, group C, member 1

decreases expression

EXP

nefazodone results in decreased expression of NR3C1 mRNA

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843

G

nuclear receptor binding protein 2

decreases expression

EXP

nefazodone results in decreased expression of NRBP2 mRNA

NCBI chr 7:109,679,330...109,685,656
Ensembl chr 7:109,679,330...109,685,588

G

neuronal regeneration related protein

decreases expression

EXP

nefazodone results in decreased expression of NREP mRNA

NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742

G

NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL

decreases expression

EXP

nefazodone results in decreased expression of NSDHL mRNA

NCBI chr X:155,817,301...155,848,224
Ensembl chr X:155,817,340...155,848,220

G

NSFL1 cofactor

increases expression

EXP

nefazodone results in increased expression of NSFL1C mRNA

NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:160,438,708...160,463,228

G

NSE1 homolog, SMC5-SMC6 complex component

increases expression

EXP

nefazodone results in increased expression of NSMCE1 mRNA

NCBI chr 1:180,030,355...180,058,541
Ensembl chr 1:189,462,677...189,491,432

G

NOP2/Sun RNA methyltransferase 2

increases expression

EXP

nefazodone results in increased expression of NSUN2 mRNA

NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:35,490,583...35,514,306

G

5' nucleotidase, ecto

decreases expression

EXP

nefazodone results in decreased expression of NT5E mRNA

NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645

G

NUBP iron-sulfur cluster assembly factor 2

increases expression

EXP

nefazodone results in increased expression of NUBP2 mRNA

NCBI chr10:14,407,743...14,411,428
Ensembl chr10:14,407,745...14,411,600

G

nucleobindin 2

decreases expression

EXP

nefazodone results in decreased expression of NUCB2 mRNA

NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116

G

nuclear casein kinase and cyclin-dependent kinase substrate 1

increases expression

EXP

nefazodone results in increased expression of NUCKS1 mRNA

NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101

G

nuclear distribution C, dynein complex regulator

increases expression

EXP

nefazodone results in increased expression of NUDC mRNA

NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260

G

nudix hydrolase 4

increases expression

EXP

nefazodone results in increased expression of NUDT4 mRNA

NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491

G

nudix hydrolase 7

increases expression

EXP

nefazodone results in increased expression of NUDT7 mRNA

NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994

G

nucleoporin 153

increases expression

EXP

nefazodone results in increased expression of NUP153 mRNA

NCBI chr17:18,178,434...18,231,109
Ensembl chr17:18,178,456...18,231,109

G

nuclear protein 1, transcriptional regulator

increases expression

EXP

nefazodone results in increased expression of NUPR1 mRNA

NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901

G

NUS1 dehydrodolichyl diphosphate synthase subunit

increases expression

EXP

nefazodone results in increased expression of NUS1 mRNA

NCBI chr20:32,354,519...32,381,265
Ensembl chr20:32,354,439...32,381,264

G

nuclear transport factor 2

increases expression

EXP

nefazodone results in increased expression of NUTF2 mRNA

NCBI chr19:50,662,168...50,683,457
Ensembl chr19:50,662,394...50,683,454

G

neurexophilin and PC-esterase domain family member 4

decreases expression

EXP

nefazodone results in decreased expression of NXPE4 mRNA

NCBI chr 8:48,502,697...48,744,101
Ensembl chr 8:57,631,895...57,644,186

G

out at first homolog

decreases expression

EXP

nefazodone results in decreased expression of OAF mRNA

NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285

G

ornithine aminotransferase

decreases expression

EXP

nefazodone results in decreased expression of OAT mRNA

NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754

G

ornithine decarboxylase 1

increases expression

EXP

nefazodone results in increased expression of ODC1 mRNA

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146

G

O-linked N-acetylglucosamine (GlcNAc) transferase

decreases expression

EXP

nefazodone results in decreased expression of OGT mRNA

NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123

G

olfactory receptor 59

decreases expression

EXP

nefazodone results in decreased expression of OLR59 mRNA

NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265

G

one cut homeobox 1

decreases expression

EXP

nefazodone results in decreased expression of ONECUT1 mRNA

NCBI chr 8:84,480,066...84,507,848
Ensembl chr 8:84,480,305...84,508,124

G

one cut homeobox 2

decreases expression

EXP

nefazodone results in decreased expression of ONECUT2 mRNA

NCBI chr18:60,101,967...60,161,095
Ensembl chr18:60,102,126...60,107,668

G

oxysterol binding protein

increases expression

EXP

nefazodone results in increased expression of OSBP mRNA

NCBI chr 1:218,313,455...218,343,263
Ensembl chr 1:218,313,148...218,343,258

G

oxysterol binding protein-like 11

increases expression

EXP

nefazodone results in increased expression of OSBPL11 mRNA

NCBI chr11:81,038,759...81,121,887
Ensembl chr11:81,038,985...81,101,299

G

ornithine transcarbamylase

decreases expression

EXP

nefazodone results in decreased expression of OTC mRNA

NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555

G

OTU deubiquitinase, ubiquitin aldehyde binding 1

increases expression

EXP

nefazodone results in increased expression of OTUB1 mRNA

NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679

G

OVCA2 serine hydrolase domain containing

increases expression

EXP

nefazodone results in increased expression of OVCA2 mRNA

NCBI chr10:60,026,048...60,029,211
Ensembl chr10:60,522,026...60,527,536

G

oxidoreductase NAD-binding domain containing 1

increases expression

EXP

nefazodone results in increased expression of OXNAD1 mRNA

NCBI chr16:7,299,755...7,328,824
Ensembl chr16:7,299,755...7,328,824

G

proliferation-associated 2G4

increases expression

EXP

nefazodone results in increased expression of PA2G4 mRNA

NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802

G

poly(A) binding protein, nuclear 1

decreases expression

EXP

nefazodone results in decreased expression of PABPN1 mRNA

NCBI chr15:32,337,955...32,342,700
Ensembl chr15:32,338,089...32,342,691

G

protein kinase C and casein kinase substrate in neurons 2

increases expression

EXP

nefazodone results in increased expression of PACSIN2 mRNA

NCBI chr 7:116,385,571...116,478,609
Ensembl chr 7:116,384,190...116,478,537

G

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

increases expression

EXP

nefazodone results in increased expression of PAFAH1B1 mRNA

NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196

G

phenylalanine hydroxylase

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of PAH mRNA

NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627

G

phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

increases expression

EXP

nefazodone results in increased expression of PAICS mRNA

NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027

G

phosphatase domain containing, paladin 1

increases expression

EXP

nefazodone results in increased expression of PALD1 mRNA

NCBI chr20:29,812,650...29,877,733
Ensembl chr20:29,812,650...29,850,063

G

palmdelphin

decreases expression

EXP

nefazodone results in decreased expression of PALMD mRNA

NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:207,574,249...207,626,239

G

polyamine oxidase

increases expression

EXP

nefazodone results in increased expression of PAOX mRNA

NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:204,348,987...204,358,481

G

progestin and adipoQ receptor family member 9

decreases expression

EXP

nefazodone results in decreased expression of PAQR9 mRNA

NCBI chr 8:104,993,884...104,996,180
Ensembl chr 8:104,993,827...104,998,285

G

poly (ADP-ribose) polymerase family, member 14

decreases expression

EXP

nefazodone results in decreased expression of PARP14 mRNA

NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195

G

poly (ADP-ribose) polymerase family, member 9

decreases expression

EXP

nefazodone results in decreased expression of PARP9 mRNA

NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608

G

phenazine biosynthesis-like protein domain containing 1

increases expression

EXP

nefazodone results in increased expression of PBLD1 mRNA

NCBI chr20:25,549,974...25,565,390
Ensembl chr20:25,549,974...25,565,226

G

PBX homeobox interacting protein 1

decreases expression

EXP

nefazodone results in decreased expression of PBXIP1 mRNA

NCBI chr 2:177,154,056...177,167,810
Ensembl chr 2:177,154,101...177,167,328

G

pyruvate carboxylase

decreases expression

EXP

nefazodone results in decreased expression of PC mRNA

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940

G

poly(rC) binding protein 1

increases expression

EXP

nefazodone results in increased expression of PCBP1 mRNA

NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:120,529,172...120,539,111

G

protocadherin 1

decreases expression

EXP

nefazodone results in decreased expression of PCDH1 mRNA

NCBI chr18:30,258,154...30,290,828
Ensembl chr18:30,258,154...30,290,436

G

protocadherin gamma subfamily C, 3

decreases expression

EXP

nefazodone results in decreased expression of PCDHGC3 mRNA

NCBI chr18:29,884,245...29,919,095

G

polycomb group ring finger 6

increases expression

EXP

nefazodone results in increased expression of PCGF6 mRNA

NCBI chr 1:255,866,709...255,886,306
Ensembl chr 1:255,866,711...255,886,266

G

phosphoenolpyruvate carboxykinase 1

decreases expression

EXP

nefazodone results in decreased expression of PCK1 mRNA

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

increases expression

EXP

nefazodone results in increased expression of PCMT1 mRNA

NCBI chr 1:3,932,161...3,980,751
Ensembl chr 1:3,932,161...3,964,848

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of PCMTD1 mRNA

NCBI chr 5:17,071,629...17,143,803
Ensembl chr 5:17,071,629...17,142,010

G

proliferating cell nuclear antigen

decreases expression

ISO

nefazodone results in decreased expression of PCNA mRNA

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

pecanex 1

decreases expression

EXP

nefazodone results in decreased expression of PCNX1 mRNA

NCBI chr 6:107,296,704...107,433,576
Ensembl chr 6:107,296,792...107,432,452

G

proprotein convertase subtilisin/kexin type 6

increases expression

EXP

nefazodone results in increased expression of PCSK6 mRNA

NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128

G

phosphatidylcholine transfer protein

decreases expression

EXP

nefazodone results in decreased expression of PCTP mRNA

NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432

G

PDGFA associated protein 1

increases expression

EXP

nefazodone results in increased expression of PDAP1 mRNA

NCBI chr12:14,584,414...14,594,641
Ensembl chr12:14,584,398...14,594,641

G

programmed cell death 11

increases expression

EXP

nefazodone results in increased expression of PDCD11 mRNA

NCBI chr 1:255,922,198...255,963,336
Ensembl chr 1:255,922,225...255,963,336

G

programmed cell death 4

decreases expression

EXP

nefazodone results in decreased expression of PDCD4 mRNA

NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189

G

phosducin-like 3

increases expression

EXP

nefazodone results in increased expression of PDCL3 mRNA

NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529

G

phosphodiesterase 2A

decreases expression

EXP

nefazodone results in decreased expression of PDE2A mRNA

NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466

G

pyruvate dehydrogenase E1 subunit alpha 1

increases expression

EXP

nefazodone results in increased expression of PDHA1 mRNA

NCBI chr X:38,509,158...38,522,986
Ensembl chr X:38,509,084...38,522,536

G

pyruvate dehydrogenase complex, component X

increases expression

EXP

nefazodone results in increased expression of PDHX mRNA

NCBI chr 3:109,826,579...109,886,869
Ensembl chr 3:109,827,209...109,886,905

G

protein disulfide isomerase family A, member 5

decreases expression

EXP

nefazodone results in decreased expression of PDIA5 mRNA

NCBI chr11:78,777,436...78,892,370
Ensembl chr11:78,777,419...78,864,329

G

pyruvate dehydrogenase kinase 2

decreases expression

EXP

nefazodone results in decreased expression of PDK2 mRNA

NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355

G

pyruvate dehydrogenase kinase 4

decreases expression

EXP

nefazodone results in decreased expression of PDK4 mRNA

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381

G

PDZ and LIM domain 1

decreases expression

EXP

nefazodone results in decreased expression of PDLIM1 mRNA

NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379

G

PDZ domain containing 1

increases expression

EXP

nefazodone results in increased expression of PDZK1 mRNA

NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806

G

phosphatidylethanolamine binding protein 1

increases expression

EXP

nefazodone results in increased expression of PEBP1 mRNA

NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780

G

peroxisomal trans-2-enoyl-CoA reductase

increases expression

EXP

nefazodone results in increased expression of PECR mRNA

NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806

G

penta-EF hand domain containing 1

increases expression

EXP

nefazodone results in increased expression of PEF1 mRNA

NCBI chr 5:147,735,973...147,759,239
Ensembl chr 5:147,735,976...147,761,092

G

pelota mRNA surveillance and ribosome rescue factor

increases expression

EXP

nefazodone results in increased expression of PELO mRNA

NCBI chr 2:48,530,902...48,532,670
Ensembl chr 2:48,530,907...48,532,761

G

peroxisomal biogenesis factor 11 alpha

increases expression

EXP

nefazodone results in increased expression of PEX11A mRNA

NCBI chr 1:143,089,410...143,096,491
Ensembl chr 1:143,089,410...143,096,645

G

peroxisomal biogenesis factor 16

increases expression

EXP

nefazodone results in increased expression of PEX16 mRNA

NCBI chr 3:98,800,357...98,808,091
Ensembl chr 3:98,798,654...98,808,630

G

peroxisomal biogenesis factor 2

increases expression

EXP

nefazodone results in increased expression of PEX2 mRNA

NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:97,948,443...97,981,092

G

peroxisomal biogenesis factor 7

increases expression

EXP

nefazodone results in increased expression of PEX7 mRNA

NCBI chr 1:16,402,319...16,466,304
Ensembl chr 1:16,402,320...16,466,366

G

prefoldin subunit 6

increases expression

EXP

nefazodone results in increased expression of PFDN6 mRNA

NCBI chr20:4,947,844...4,949,318
Ensembl chr20:4,947,844...4,949,318

G

profilin 1

increases expression

EXP

nefazodone results in increased expression of PFN1 mRNA

NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611

G

phosphoglycerate mutase 1

increases expression

EXP

nefazodone results in increased expression of PGAM1 mRNA

NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203

G

pyroglutamyl-peptidase I

decreases expression

EXP

nefazodone results in decreased expression of PGPEP1 mRNA

NCBI chr16:18,804,408...18,817,466
Ensembl chr16:18,805,009...18,817,462

G

progesterone receptor membrane component 1

increases expression

EXP

nefazodone results in increased expression of PGRMC1 mRNA

NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805

G

progesterone receptor membrane component 2

decreases expression

EXP

nefazodone results in decreased expression of PGRMC2 mRNA

NCBI chr 2:125,996,190...126,012,090
Ensembl chr 2:125,996,193...126,012,090

G

prohibitin 1

increases expression

EXP

nefazodone results in increased expression of PHB1 mRNA

NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233

G

PHD finger protein 5A

increases expression

EXP

nefazodone results in increased expression of PHF5A mRNA

NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174

G

phosphoglycerate dehydrogenase

increases expression

EXP

nefazodone results in increased expression of PHGDH mRNA

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789

G

pleckstrin homology-like domain, family B, member 2

decreases expression

EXP

nefazodone results in decreased expression of PHLDB2 mRNA

NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734

G

putative homeodomain transcription factor 1

decreases expression

EXP

nefazodone results in decreased expression of PHTF1 mRNA

NCBI chr 2:194,161,343...194,249,925
Ensembl chr 2:194,161,000...194,219,530

G

phosphatidylinositol 4-kinase type 2 beta

increases expression

EXP

nefazodone results in increased expression of PI4K2B mRNA

NCBI chr14:62,434,589...62,461,507
Ensembl chr14:62,424,511...62,461,446

G

phosphatidylinositol 4-kinase alpha

increases expression

EXP

nefazodone results in increased expression of PI4KA mRNA

NCBI chr11:97,113,390...97,234,374
Ensembl chr11:97,113,245...97,228,315

G

phosphotyrosine interaction domain containing 1

increases expression

ISO

nefazodone results in increased expression of PID1 mRNA

NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:92,734,214...92,750,070

G

phosphatidylinositol glycan anchor biosynthesis, class C

increases expression

EXP

nefazodone results in increased expression of PIGC mRNA

NCBI chr13:76,876,894...76,879,420
Ensembl chr13:76,872,922...76,880,224

G

phosphatidylinositol glycan anchor biosynthesis, class K

increases expression

EXP

nefazodone results in increased expression of PIGK mRNA

NCBI chr 2:244,289,928...244,375,394
Ensembl chr 2:244,250,621...244,376,030

G

phosphatidylinositol glycan anchor biosynthesis, class P

decreases expression

EXP

nefazodone results in decreased expression of PIGP mRNA

NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082

G

phosphatidylinositol glycan anchor biosynthesis, class X

increases expression

EXP

nefazodone results in increased expression of PIGX mRNA

NCBI chr11:82,192,125...82,208,062
Ensembl chr11:82,192,092...82,208,061

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of PIK3C2B mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C2B mRNA

NCBI chr13:47,046,866...47,107,733
Ensembl chr13:47,047,127...47,107,725

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of PIK3C2G mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C2G mRNA

NCBI chr 4:174,215,527...174,583,378
Ensembl chr 4:174,215,527...174,581,705

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of PIK3C3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C3 mRNA

NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of PIK3R1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

G

Pim-3 proto-oncogene, serine/threonine kinase

increases expression

EXP

nefazodone results in increased expression of PIM3 mRNA

NCBI chr 7:121,822,076...121,836,257
Ensembl chr 7:121,832,742...121,836,259

G

PTEN induced kinase 1

increases expression

EXP

nefazodone results in increased expression of PINK1 mRNA

NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950

G

pirin

increases expression

EXP

nefazodone results in increased expression of PIR mRNA

NCBI chr X:33,740,428...33,851,049
Ensembl chr X:33,740,429...33,851,049

G

PITH domain containing 1

increases expression

EXP

nefazodone results in increased expression of PITHD1 mRNA

NCBI chr 5:148,205,995...148,216,490
Ensembl chr 5:153,489,529...153,500,261

G

protein kinase domain containing, cytoplasmic

decreases expression

EXP

nefazodone results in decreased expression of PKDCC mRNA

NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042

G

pyruvate kinase L/R

decreases expression

EXP

nefazodone results in decreased expression of PKLR mRNA

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644

G

phospholipase A2, group XIIA

increases expression

EXP

nefazodone results in increased expression of PLA2G12A mRNA

NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964

G

phospholipase A2, activating protein

increases expression

EXP

nefazodone results in increased expression of PLAA mRNA

NCBI chr 5:114,544,327...114,576,023
Ensembl chr 5:114,544,325...114,576,109

G

phospholipase A and acyltransferase 3

decreases expression

EXP

nefazodone results in decreased expression of PLAAT3 mRNA

NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:214,211,791...214,246,763

G

phospholipase B domain containing 1

decreases expression

EXP

nefazodone results in decreased expression of PLBD1 mRNA

NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488

G

pleckstrin homology domain containing B1

decreases expression

EXP

nefazodone results in decreased expression of PLEKHB1 mRNA

NCBI chr 1:164,410,901...164,425,216
Ensembl chr 1:164,410,903...164,428,568

G

plasminogen

decreases expression

EXP

nefazodone results in decreased expression of PLG mRNA

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

increases expression

EXP

nefazodone results in increased expression of PLOD1 mRNA

NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110

G

pyridoxal phosphate binding protein

increases expression

EXP

nefazodone results in increased expression of PLPBP mRNA

NCBI chr16:71,705,064...71,717,726
Ensembl chr16:71,700,028...71,717,726

G

phospholipid phosphatase 2

increases expression

EXP

nefazodone results in increased expression of PLPP2 mRNA

NCBI chr 7:10,826,534...10,834,628
Ensembl chr 7:10,826,549...10,834,627

G

phospholipid phosphatase 3

decreases expression

EXP

nefazodone results in decreased expression of PLPP3 mRNA

NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667

G

plastin 3

increases expression

EXP

nefazodone results in increased expression of PLS3 mRNA

NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893

G

plexin A2

decreases expression

EXP

nefazodone results in decreased expression of PLXNA2 mRNA

NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453

G

plexin B2

decreases expression

EXP

nefazodone results in decreased expression of PLXNB2 mRNA

NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

ISO

nefazodone results in increased expression of PMAIP1 mRNA

NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382

G

peptidase, mitochondrial processing subunit alpha

increases expression

EXP

nefazodone results in increased expression of PMPCA mRNA

NCBI chr 3:29,605,823...29,614,936
Ensembl chr 3:29,604,232...29,614,935

G

phosphomevalonate kinase

decreases expression

EXP

nefazodone results in decreased expression of PMVK mRNA

NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080

G

PNN interacting serine and arginine rich protein

decreases expression

EXP

nefazodone results in decreased expression of PNISR mRNA

NCBI chr 5:40,190,214...40,219,619
Ensembl chr 5:40,192,735...40,219,611

G

pinin, desmosome associated protein

decreases expression

EXP

nefazodone results in decreased expression of PNN mRNA

NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933

G

partner of NOB1 homolog

increases expression

EXP

nefazodone results in increased expression of PNO1 mRNA

NCBI chr14:95,811,335...95,819,903
Ensembl chr14:95,688,125...95,905,881

G

patatin-like phospholipase domain containing 2

increases expression

EXP

nefazodone results in increased expression of PNPLA2 mRNA

NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359

G

patatin-like phospholipase domain containing 7

increases expression

EXP

nefazodone results in increased expression of PNPLA7 mRNA

NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672

G

patatin-like phospholipase domain containing 8

increases expression

EXP

nefazodone results in increased expression of PNPLA8 mRNA

NCBI chr 6:67,056,783...67,118,714
Ensembl chr 6:67,056,697...67,120,512

G

proline-rich nuclear receptor coactivator 1

decreases expression

EXP

nefazodone results in decreased expression of PNRC1 mRNA

NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491

G

DNA polymerase delta 4, accessory subunit

increases expression

EXP

nefazodone results in increased expression of POLD4 mRNA

NCBI chr 1:210,956,110...210,957,863
Ensembl chr 1:210,956,099...210,957,860

G

DNA polymerase delta interacting protein 2

increases expression

EXP

nefazodone results in increased expression of POLDIP2 mRNA

NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,904,691...63,915,655

G

DNA polymerase epsilon 4, accessory subunit

increases expression

EXP

nefazodone results in increased expression of POLE4 mRNA

NCBI chr 4:115,165,285...115,171,097
Ensembl chr 4:116,716,719...116,728,851

G

DNA polymerase gamma 2, accessory subunit

increases expression

EXP

nefazodone results in increased expression of POLG2 mRNA

NCBI chr10:92,212,303...92,222,849
Ensembl chr10:92,212,304...92,222,726

G

RNA polymerase I subunit F

increases expression

EXP

nefazodone results in increased expression of POLR1F mRNA

NCBI chr 6:55,780,706...55,797,935
Ensembl chr 6:55,780,706...55,797,935

G

RNA polymerase III subunit D

increases expression

EXP

nefazodone results in increased expression of POLR3D mRNA

NCBI chr15:51,921,283...51,925,952
Ensembl chr15:51,921,283...51,925,691

G

proteasome maturation protein

increases expression

EXP

nefazodone results in increased expression of POMP mRNA

NCBI chr12:12,198,262...12,212,132
Ensembl chr12:12,198,263...12,210,880

G

paraoxonase 3

decreases expression

EXP

nefazodone results in decreased expression of PON3 mRNA

NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244

G

POP5 homolog, ribonuclease P/MRP subunit

increases expression

EXP

nefazodone results in increased expression of POP5 mRNA

NCBI chr12:47,037,451...47,045,778
Ensembl chr12:47,029,403...47,042,032

G

cytochrome p450 oxidoreductase

increases expression

EXP

nefazodone results in increased expression of POR mRNA

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809

G

inorganic pyrophosphatase 1

increases expression

EXP

nefazodone results in increased expression of PPA1 mRNA

NCBI chr20:30,132,088...30,160,492
Ensembl chr20:30,133,504...30,160,489

G

inorganic pyrophosphatase 2

decreases expression

EXP

nefazodone results in decreased expression of PPA2 mRNA

NCBI chr 2:221,800,791...221,878,079
Ensembl chr 2:224,474,823...224,552,628

G

peter pan homolog

increases expression

EXP

nefazodone results in increased expression of PPAN mRNA

NCBI chr 8:27,700,147...27,704,127
Ensembl chr 8:27,700,152...27,704,128

G

peroxisome proliferator activated receptor alpha

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

phosphoribosyl pyrophosphate amidotransferase

increases expression

EXP

nefazodone results in increased expression of PPAT mRNA

NCBI chr14:31,570,010...31,604,410
Ensembl chr14:31,551,388...31,604,405

G

phosphopantothenoylcysteine synthetase

increases expression

EXP

nefazodone results in increased expression of PPCS mRNA

NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:138,308,397...138,312,012

G

pancreatic progenitor cell differentiation and proliferation factor

decreases expression

EXP

nefazodone results in decreased expression of PPDPF mRNA

NCBI chr 3:188,676,821...188,678,599
Ensembl chr 3:188,676,965...188,678,599

G

PPFIA binding protein 2

decreases expression

EXP

nefazodone results in decreased expression of PPFIBP2 mRNA

NCBI chr 1:170,916,649...171,062,096
Ensembl chr 1:170,916,649...171,065,618

G

peptidylprolyl isomerase E

increases expression

EXP

nefazodone results in increased expression of PPIE mRNA

NCBI chr 5:140,691,285...140,704,347
Ensembl chr 5:140,683,801...140,740,767

G

protein phosphatase, Mg2+/Mn2+ dependent, 1K

increases expression

EXP

nefazodone results in increased expression of PPM1K mRNA

NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:88,942,386...88,969,136

G

protein phosphatase 1 catalytic subunit beta

increases expression

EXP

nefazodone results in increased expression of PPP1CB mRNA

NCBI chr 6:29,681,099...29,712,835
Ensembl chr 6:29,681,100...29,712,924

G

protein phosphatase 1, regulatory (inhibitor) subunit 14B

increases expression

EXP

nefazodone results in increased expression of PPP1R14B mRNA

NCBI chr 1:213,594,416...213,596,527
Ensembl chr12:21,088,517...21,101,431
Ensembl chr 1:21,088,517...21,101,431

G

protein phosphatase 1, regulatory subunit 21

decreases expression

EXP

nefazodone results in decreased expression of PPP1R21 mRNA

NCBI chr 6:5,901,518...5,970,684
Ensembl chr 6:11,655,059...11,724,219

G

protein phosphatase 1, regulatory subunit 3B

decreases expression

EXP

nefazodone results in decreased expression of PPP1R3B mRNA

NCBI chr16:63,533,318...63,545,683
Ensembl chr16:63,532,842...63,549,997

G

protein phosphatase 1, regulatory subunit 3C

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of PPP1R3C mRNA

NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835

G

protein phosphatase 2 catalytic subunit beta

increases expression

EXP

nefazodone results in increased expression of PPP2CB mRNA

NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634

G

protein phosphatase 2 scaffold subunit A alpha

increases expression

EXP

nefazodone results in increased expression of PPP2R1A mRNA

NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242

G

protein phosphatase 2, regulatory subunit B, delta

increases expression

EXP

nefazodone results in increased expression of PPP2R2D mRNA

NCBI chr 1:203,095,536...203,129,895
Ensembl chr 1:203,095,531...203,129,893

G

protein phosphatase 2, regulatory subunit B', alpha

decreases expression

EXP

nefazodone results in decreased expression of PPP2R5A mRNA

NCBI chr13:105,462,371...105,506,767
Ensembl chr13:105,462,371...105,506,767

G

protein phosphatase 2 regulatory subunit B', epsilon

decreases expression

EXP

nefazodone results in decreased expression of PPP2R5E mRNA

NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573

G

protein phosphatase 3 catalytic subunit beta

increases expression

EXP

nefazodone results in increased expression of PPP3CB mRNA

NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203

G

protein phosphatase 3, regulatory subunit B, alpha

increases expression

EXP

nefazodone results in increased expression of PPP3R1 mRNA

NCBI chr14:95,758,333...95,808,015

G

protein phosphatase 6, catalytic subunit

increases expression

EXP

nefazodone results in increased expression of PPP6C mRNA

NCBI chr 3:43,339,521...43,371,807
Ensembl chr 3:43,341,108...43,371,807

G

peroxiredoxin 1

increases expression

EXP

nefazodone results in increased expression of PRDX1 mRNA

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504

G

peroxiredoxin 3

increases expression

EXP

nefazodone results in increased expression of PRDX3 mRNA

NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300

G

peroxiredoxin 5

increases expression

EXP

nefazodone results in increased expression of PRDX5 mRNA

NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020

G

peroxiredoxin 6

increases expression

EXP

nefazodone results in increased expression of PRDX6 mRNA

NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657

G

prolactin regulatory element binding

increases expression

EXP

nefazodone results in increased expression of PREB mRNA

NCBI chr 6:31,138,757...31,142,544
Ensembl chr 6:31,138,743...31,142,540

G

PRELI domain containing 3B

increases expression

EXP

nefazodone results in increased expression of PRELID3B mRNA

NCBI chr 3:163,263,059...163,271,055
Ensembl chr 3:183,681,255...183,689,289

G

protein kinase AMP-activated non-catalytic subunit beta 1

decreases expression

EXP

nefazodone results in decreased expression of PRKAB1 mRNA

NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482

G

protein kinase cAMP-activated catalytic subunit alpha

decreases expression

EXP

nefazodone results in decreased expression of PRKACA mRNA

NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494

G

protein kinase cAMP-dependent type I regulatory subunit alpha

increases expression

EXP

nefazodone results in increased expression of PRKAR1A mRNA

NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025

G

protein kinase C, iota

increases expression

EXP

nefazodone results in increased expression of PRKCI mRNA

NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:114,250,398...114,310,784

G

protein arginine methyltransferase 1

increases expression

EXP

nefazodone results in increased expression of PRMT1 mRNA

NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:104,595,335...104,604,827

G

proline dehydrogenase

decreases expression

EXP

nefazodone results in decreased expression of PRODH mRNA

NCBI chr11:96,414,275...96,431,604
Ensembl chr11:96,414,224...96,433,418

G

pre-mRNA processing factor 19

increases expression

EXP

nefazodone results in increased expression of PRPF19 mRNA

NCBI chr 1:216,966,104...216,977,549
Ensembl chr 1:216,966,462...216,980,506

G

phosphoribosyl pyrophosphate synthetase 1

increases expression

EXP

nefazodone results in increased expression of PRPS1 mRNA

NCBI chr X:108,920,663...108,942,713
Ensembl chr X:108,920,651...108,942,711

G

serine protease 23

decreases expression

EXP

nefazodone results in decreased expression of PRSS23 mRNA

NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:152,813,670...152,947,871

G

peroxiredoxin like 2B

decreases expression

EXP

nefazodone results in decreased expression of PRXL2B mRNA

NCBI chr 5:170,744,953...170,747,556
Ensembl chr 5:170,744,953...170,747,556

G

phosphoserine aminotransferase 1

increases expression

EXP

nefazodone results in increased expression of PSAT1 mRNA

NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693

G

proteasome 20S subunit alpha 1

increases expression

EXP

nefazodone results in increased expression of PSMA1 mRNA

NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:177,875,353...177,887,949

G

proteasome 20S subunit alpha 2

increases expression

EXP

nefazodone results in increased expression of PSMA2 mRNA

NCBI chr17:55,250,054...55,260,441
Ensembl chr17:55,247,442...55,339,673

G

proteasome 20S subunit alpha 3

increases expression

EXP

nefazodone results in increased expression of PSMA3 mRNA

NCBI chr 6:95,219,714...95,239,745
Ensembl chr 6:95,219,629...95,241,032

G

proteasome 20S subunit alpha 4

increases expression

EXP

nefazodone results in increased expression of PSMA4 mRNA

NCBI chr 8:64,236,520...64,243,980
Ensembl chr 8:64,236,783...64,243,979

G

proteasome 20S subunit alpha 5

increases expression

EXP

nefazodone results in increased expression of PSMA5 mRNA

NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867

G

proteasome 20S subunit alpha 6

increases expression

EXP

nefazodone results in increased expression of PSMA6 mRNA

NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717

G

proteasome 20S subunit alpha 7

increases expression

EXP

nefazodone results in increased expression of PSMA7 mRNA

NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253

G

proteasome 20S subunit beta 1

increases expression

EXP

nefazodone results in increased expression of PSMB1 mRNA

NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640

G

proteasome 20S subunit beta 2

increases expression

EXP

nefazodone results in increased expression of PSMB2 mRNA

NCBI chr 5:144,255,058...144,287,200
Ensembl chr 5:144,255,026...144,287,608

G

proteasome 20S subunit beta 3

increases expression

EXP

nefazodone results in increased expression of PSMB3 mRNA

NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883

G

proteasome 20S subunit beta 4

increases expression

EXP

nefazodone results in increased expression of PSMB4 mRNA

NCBI chr 2:185,131,787...185,134,561
Ensembl chr 2:185,131,786...185,135,287

G

proteasome 20S subunit beta 5

increases expression

EXP

nefazodone results in increased expression of PSMB5 mRNA

NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379

G

proteasome 20S subunit beta 6

increases expression

EXP

nefazodone results in increased expression of PSMB6 mRNA

NCBI chr10:55,737,852...55,740,218
Ensembl chr10:55,737,888...55,740,218

G

proteasome 20S subunit beta 7

increases expression

EXP

nefazodone results in increased expression of PSMB7 mRNA

NCBI chr 3:42,767,500...42,827,470
Ensembl chr 3:42,767,501...42,827,601

G

proteasome 20S subunit beta 8

decreases expression

EXP

nefazodone results in decreased expression of PSMB8 mRNA

NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031

G

proteasome 20S subunit beta 9

decreases expression

EXP

nefazodone results in decreased expression of PSMB9 mRNA

NCBI chr20:4,668,952...4,674,421
Ensembl chr20:4,668,739...4,674,421

G

proteasome 26S subunit, ATPase 1

increases expression

EXP

nefazodone results in increased expression of PSMC1 mRNA

NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858

G

proteasome 26S subunit, ATPase 2

increases expression

EXP

nefazodone results in increased expression of PSMC2 mRNA

NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390

G

proteasome 26S subunit, ATPase 3

increases expression

EXP

nefazodone results in increased expression of PSMC3 mRNA

NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176

G

proteasome 26S subunit, ATPase 4

increases expression

EXP

nefazodone results in increased expression of PSMC4 mRNA

NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060

G

proteasome 26S subunit, ATPase 5

increases expression

EXP

nefazodone results in increased expression of PSMC5 mRNA

NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921

G

proteasome 26S subunit, ATPase 6

increases expression

EXP

nefazodone results in increased expression of PSMC6 mRNA

NCBI chr15:21,022,314...21,043,785
Ensembl chr15:21,022,314...21,043,785

G

proteasome 26S subunit, non-ATPase 1

increases expression

EXP

nefazodone results in increased expression of PSMD1 mRNA

NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218

G

proteasome 26S subunit, non-ATPase 11

increases expression

EXP

nefazodone results in increased expression of PSMD11 mRNA

NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234

G

proteasome 26S subunit, non-ATPase 12

increases expression

EXP

nefazodone results in increased expression of PSMD12 mRNA

NCBI chr10:92,937,957...92,956,601
Ensembl chr10:92,901,133...92,988,964

G

proteasome 26S subunit, non-ATPase 13

increases expression

EXP

nefazodone results in increased expression of PSMD13 mRNA

NCBI chr 1:205,394,248...205,406,525
Ensembl chr 1:205,393,746...205,411,651

G

proteasome 26S subunit, non-ATPase 14

increases expression

EXP

nefazodone results in increased expression of PSMD14 mRNA

NCBI chr 3:66,662,933...66,755,666
Ensembl chr 3:66,662,900...66,755,665

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 2

increases expression

EXP

nefazodone results in increased expression of PSMD2 mRNA

NCBI chr11:93,752,761...93,763,388
Ensembl chr11:93,752,763...93,763,388

G

proteasome 26S subunit, non-ATPase 3

increases expression

EXP

nefazodone results in increased expression of PSMD3 mRNA

NCBI chr10:84,139,249...84,151,879
Ensembl chr10:84,139,677...84,151,878

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 4

increases expression

EXP

nefazodone results in increased expression of PSMD4 mRNA

NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201

G

proteasome 26S subunit, non-ATPase 5

increases expression

EXP

nefazodone results in increased expression of PSMD5 mRNA

NCBI chr 3:38,531,206...38,552,085
Ensembl chr 3:38,530,951...38,548,490

G

proteasome 26S subunit, non-ATPase 6

increases expression

EXP

nefazodone results in increased expression of PSMD6 mRNA

NCBI chr15:13,532,675...13,542,682
Ensembl chr15:13,532,675...13,542,682

G

proteasome 26S subunit, non-ATPase 7

increases expression

EXP

nefazodone results in increased expression of PSMD7 mRNA

NCBI chr19:52,404,032...52,411,316
Ensembl chr19:52,404,032...52,417,871

G

proteasome 26S subunit, non-ATPase 8

increases expression

EXP

nefazodone results in increased expression of PSMD8 mRNA

NCBI chr 1:93,601,857...93,608,689
Ensembl chr 1:93,601,853...93,608,689

G

proteasome 26S subunit, non-ATPase 9

increases expression

EXP

nefazodone results in increased expression of PSMD9 mRNA

NCBI chr12:38,998,027...39,018,340
Ensembl chr12:38,998,030...39,018,679

G

proteasome activator subunit 3

increases expression

EXP

nefazodone results in increased expression of PSME3 mRNA

NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033

G

proteasome activator subunit 4

increases expression

EXP

nefazodone results in increased expression of PSME4 mRNA

NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328

G

proteasome assembly chaperone 2

increases expression

EXP

nefazodone results in increased expression of PSMG2 mRNA

NCBI chr18:61,208,669...61,227,671

G

proteasome assembly chaperone 3

increases expression

EXP

nefazodone results in increased expression of PSMG3 mRNA

NCBI chr12:19,923,288...19,926,205
Ensembl chr12:19,923,288...19,926,205

G

phosphatase and tensin homolog

increases expression

EXP

nefazodone results in increased expression of PTEN mRNA

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330

G

prostaglandin E synthase 3-like 1

increases expression

EXP

nefazodone results in increased expression of PTGES3L1 mRNA

NCBI chr X:42,215,200...42,224,472
Ensembl chr X:46,092,206...46,107,019

G

prostaglandin reductase 3

increases expression

EXP

nefazodone results in increased expression of PTGR3 mRNA

NCBI chr18:79,729,282...79,738,632
Ensembl chr18:79,729,282...79,738,632

G

parathymosin

decreases expression

EXP

nefazodone results in decreased expression of PTMS mRNA

NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212

G

protein tyrosine phosphatase, mitochondrial 1

increases expression

EXP

nefazodone results in increased expression of PTPMT1 mRNA

NCBI chr 3:97,345,752...97,355,396
Ensembl chr 3:97,345,752...97,355,254

G

protein tyrosine phosphatase, non-receptor type 11

increases expression

EXP

nefazodone results in increased expression of PTPN11 mRNA

NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577

G

protein tyrosine phosphatase, non-receptor type 21

increases expression

EXP

nefazodone results in increased expression of PTPN21 mRNA

NCBI chr 6:123,662,783...123,727,809
Ensembl chr 6:123,662,783...123,727,809

G

protein tyrosine phosphatase, receptor type, B

decreases expression

EXP

nefazodone results in decreased expression of PTPRB mRNA

NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:53,816,097...53,920,760

G

protein tyrosine phosphatase, receptor type, D

decreases expression

EXP

nefazodone results in decreased expression of PTPRD mRNA

NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903

G

protein tyrosine phosphatase, receptor type, F

decreases expression

EXP

nefazodone results in decreased expression of PTPRF mRNA

NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426

G

pumilio RNA-binding family member 3

increases expression

EXP

nefazodone results in increased expression of PUM3 mRNA

NCBI chr 1:234,483,482...234,527,718
Ensembl chr 1:234,487,954...234,527,612

G

pumilio RNA-binding family member 3 like 1

increases expression

EXP

nefazodone results in increased expression of PUM3L1 mRNA

NCBI chr X:149,570,869...149,572,962
Ensembl chr X:154,615,648...154,617,733

G

pseudouridine synthase 1

increases expression

EXP

nefazodone results in increased expression of PUS1 mRNA

NCBI chr12:51,539,659...51,548,975
Ensembl chr12:51,540,212...51,548,973

G

glycogen phosphorylase L

decreases expression

EXP

nefazodone results in decreased expression of PYGL mRNA

NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269

G

R3H domain containing 2

decreases expression

EXP

nefazodone results in decreased expression of R3HDM2 mRNA

NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862

G

RAB11B, member RAS oncogene family

decreases expression

EXP

nefazodone results in decreased expression of RAB11B mRNA

NCBI chr 7:15,223,613...15,236,754
Ensembl chr 7:15,223,534...15,236,756

G

RAB21, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB21 mRNA

NCBI chr 7:52,790,158...52,814,943
Ensembl chr 7:52,790,165...52,814,943

G

RAB28, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB28 mRNA

NCBI chr14:69,245,846...69,322,968
Ensembl chr14:73,458,249...73,535,369

G

RAB2A, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB2A mRNA

NCBI chr 5:26,473,424...26,537,441
Ensembl chr 5:26,473,548...26,538,488

G

RAB30, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB30 mRNA

NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:156,216,137...156,310,778

G

RAB34, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB34 mRNA

NCBI chr10:63,581,542...63,585,608
Ensembl chr10:63,580,997...63,586,083

G

RAB38, member RAS oncogene family

decreases expression

EXP

nefazodone results in decreased expression of RAB38 mRNA

NCBI chr 1:151,595,153...151,675,492
Ensembl chr 1:151,595,078...151,675,493

G

RAB5A, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB5A mRNA

NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,721,122...6,749,447

G

RAB5 interacting factor

increases expression

EXP

nefazodone results in increased expression of RAB5IF mRNA

NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067

G

RAB6A, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAB6A mRNA

NCBI chr 1:164,370,033...164,422,324
Ensembl chr 1:164,369,861...164,417,763

G

RAB7A, member RAS oncogene family

decreases expression

EXP

nefazodone results in decreased expression of RAB7A mRNA

NCBI chr 4:122,019,281...122,068,067
Ensembl chr 4:121,983,938...122,064,185

G

receptor for activated C kinase 1

increases expression

EXP

nefazodone results in increased expression of RACK1 mRNA

NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948

G

RAD23 homolog B, nucleotide excision repair protein

increases expression

EXP

nefazodone results in increased expression of RAD23B mRNA

NCBI chr 5:74,885,518...74,923,621
Ensembl chr 5:74,885,516...74,962,426

G

RAS like proto-oncogene A

increases expression
multiple interactions

ISO

nefazodone results in increased expression of RALA mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RALA mRNA

NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733

G

RNA guanine-7 methyltransferase activating subunit

increases expression

EXP

nefazodone results in increased expression of RAMAC mRNA

NCBI chr 1:145,117,752...145,123,640
Ensembl chr 1:145,117,736...145,124,256

G

RAN, member RAS oncogene family

increases expression

EXP

nefazodone results in increased expression of RAN mRNA

NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317

G

RAN binding protein 2

increases expression

EXP

nefazodone results in increased expression of RANBP2 mRNA

NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571

G

RAN GTPase activating protein 1

increases expression

EXP

nefazodone results in increased expression of RANGAP1 mRNA

NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564

G

RAP1A, member of RAS oncogene family

multiple interactions
decreases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of RAP1A mRNA
nefazodone results in decreased expression of RAP1A mRNA

NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808

G

retinoic acid receptor, beta

decreases expression

EXP

nefazodone results in decreased expression of RARB mRNA

NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040

G

retinoic acid receptor responder 1

decreases expression

EXP

nefazodone results in decreased expression of RARRES1 mRNA

NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024

G

retinoic acid receptor responder 2

decreases expression

EXP

nefazodone results in decreased expression of RARRES2 mRNA

NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457

G

arginyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of RARS1 mRNA

NCBI chr10:20,774,804...20,799,251
Ensembl chr10:20,774,805...20,799,251

G

RB transcriptional corepressor 1

decreases expression

EXP

nefazodone results in decreased expression of RB1 mRNA

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

RB binding protein 7, chromatin remodeling factor

increases expression

EXP

nefazodone results in increased expression of RBBP7 mRNA

NCBI chr X:35,544,873...35,563,030
Ensembl chr X:35,544,873...35,563,030

G

ribosome binding factor A

decreases expression

EXP

nefazodone results in decreased expression of RBFA mRNA

NCBI chr18:75,914,247...75,923,893
Ensembl chr18:75,914,145...75,939,219

G

ribosomal biogenesis factor

increases expression

EXP

nefazodone results in increased expression of RBIS mRNA

NCBI chr 2:88,702,599...88,718,587
Ensembl chr 2:88,702,536...88,719,527

G

RNA binding motif protein 26

decreases expression

EXP

nefazodone results in decreased expression of RBM26 mRNA

NCBI chr15:88,299,378...88,379,365
Ensembl chr15:88,301,436...88,378,686

G

RNA binding motif protein 3

increases expression

EXP

nefazodone results in increased expression of RBM3 mRNA

NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841

G

RNA binding motif protein 39

decreases expression

EXP

nefazodone results in decreased expression of RBM39 mRNA

NCBI chr 3:165,123,087...165,156,453
Ensembl chr 3:165,123,095...165,149,397

G

RNA binding protein, mRNA processing factor

increases expression

EXP

nefazodone results in increased expression of RBPMS mRNA

NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503

G

ring-box 1

increases expression

EXP

nefazodone results in increased expression of RBX1 mRNA

NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:114,870,972...114,881,191

G

regulator of calcineurin 1

decreases expression

EXP

nefazodone results in decreased expression of RCAN1 mRNA

NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236

G

regulator of calcineurin 2

increases expression

EXP

nefazodone results in increased expression of RCAN2 mRNA

NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:24,456,861...24,672,189

G

regulator of chromosome condensation 2

increases expression

EXP

nefazodone results in increased expression of RCC2 mRNA

NCBI chr 5:158,277,476...158,300,294
Ensembl chr 5:158,277,476...158,300,294

G

ring finger and CHY zinc finger domain containing 1

increases expression

EXP

nefazodone results in increased expression of RCHY1 mRNA

NCBI chr14:16,397,533...16,413,286
Ensembl chr14:16,397,494...16,413,451

G

retinol dehydrogenase 11

decreases expression

EXP

nefazodone results in decreased expression of RDH11 mRNA

NCBI chr 6:103,712,373...103,728,247
Ensembl chr 6:103,712,374...103,729,741

G

retinol dehydrogenase 16

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of RDH16 mRNA

NCBI chr 7:65,499,763...65,510,304

G

receptor accessory protein 5

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of REEP5 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of REEP5 mRNA

PMID:24136188 PMID:33819548

NCBI chr18:26,219,528...26,257,505
Ensembl chr18:26,219,530...26,250,660

G

receptor accessory protein 6

increases expression

EXP

nefazodone results in increased expression of REEP6 mRNA

NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:10,024,602...10,031,740

G

reelin

decreases expression

EXP

nefazodone results in decreased expression of RELN mRNA

NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162

G

reticulophagy regulator 1

increases expression

EXP

nefazodone results in increased expression of RETREG1 mRNA

NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:78,066,031...78,225,356

G

required for excision 1-B domain containing

increases expression

EXP

nefazodone results in increased expression of REX1BD mRNA

NCBI chr16:18,956,023...18,958,494
Ensembl chr16:18,955,969...18,958,494

G

RNA exonuclease 2

increases expression

EXP

nefazodone results in increased expression of REXO2 mRNA

NCBI chr 8:57,708,420...57,720,142
Ensembl chr 8:57,707,558...57,720,142

G

riboflavin kinase

increases expression

EXP

nefazodone results in increased expression of RFK mRNA

NCBI chr 1:224,226,632...224,234,185
Ensembl chr 1:224,226,628...224,235,698
Ensembl chr X:224,226,628...224,235,698

G

riboflavin kinase, pseudogene 3

increases expression

EXP

nefazodone results in increased expression of RFK-PS3 mRNA

NCBI chr 3:86,510,729...86,512,353
Ensembl chr 3:106,954,321...106,967,418

G

regucalcin

decreases expression

EXP

nefazodone results in decreased expression of RGN mRNA

NCBI chr X:4,172,537...4,190,112
Ensembl chr X:4,172,537...4,190,251

G

rhomboid domain containing 2

increases expression

EXP

nefazodone results in increased expression of RHBDD2 mRNA

NCBI chr12:26,680,206...26,690,926
Ensembl chr12:26,680,969...26,691,080

G

Ras homolog, mTORC1 binding

increases expression

EXP

nefazodone results in increased expression of RHEB mRNA

NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:11,012,643...11,053,931

G

ras homolog family member B

decreases expression

EXP

nefazodone results in decreased expression of RHOB mRNA

NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772

G

reactive intermediate imine deaminase A homolog

decreases expression

EXP

nefazodone results in decreased expression of RIDA mRNA

NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692

G

RNA sensor RIG-1

decreases expression

EXP

nefazodone results in decreased expression of RIGI mRNA

NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995

G

RIO kinase 3

increases expression

EXP

nefazodone results in increased expression of RIOK3 mRNA

NCBI chr18:3,602,535...3,628,108
Ensembl chr18:3,602,535...3,628,108

G

receptor interacting serine/threonine kinase 1

increases expression
multiple interactions

ISO

nefazodone results in increased expression of RIPK1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RIPK1 mRNA

NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167

G

regulator of microtubule dynamics 2

decreases expression

EXP

nefazodone results in decreased expression of RMDN2 mRNA

NCBI chr 6:21,101,383...21,195,221
Ensembl chr 6:21,119,396...21,193,684

G

RecQ mediated genome instability 1

decreases expression

EXP

nefazodone results in decreased expression of RMI1 mRNA

NCBI chr17:6,261,961...6,269,947
Ensembl chr17:6,260,896...6,282,052

G

ribonuclease A family member 4

decreases expression

EXP

nefazodone results in decreased expression of RNASE4 mRNA

NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639

G

ring finger protein 10

increases expression

EXP

nefazodone results in increased expression of RNF10 mRNA

NCBI chr12:47,002,409...47,036,201
Ensembl chr12:47,002,409...47,036,201

G

ring finger protein 113A2

increases expression

EXP

nefazodone results in increased expression of RNF113A2 mRNA

NCBI chr 6:104,063,677...104,064,958
Ensembl chr 6:109,794,684...109,796,273

G

ring finger protein 114

increases expression

EXP

nefazodone results in increased expression of RNF114 mRNA

NCBI chr 3:176,641,456...176,653,262
Ensembl chr 3:176,641,499...176,671,960

G

ring finger protein 115

increases expression

EXP

nefazodone results in increased expression of RNF115 mRNA

NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:186,950,760...187,019,561

G

ring finger protein 125

decreases expression

EXP

nefazodone results in decreased expression of RNF125 mRNA

NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,528,838...12,554,430

G

ring finger protein 139

increases expression

EXP

nefazodone results in increased expression of RNF139 mRNA

NCBI chr 7:92,329,201...92,340,386
Ensembl chr 7:92,329,157...92,341,721

G

ring finger protein 14

increases expression

EXP

nefazodone results in increased expression of RNF14 mRNA

NCBI chr18:30,381,072...30,406,859
Ensembl chr18:30,382,857...30,406,774

G

ring finger protein 149

increases expression

EXP

nefazodone results in increased expression of RNF149 mRNA

NCBI chr 9:49,322,524...49,350,361
Ensembl chr 9:49,323,857...49,350,042

G

ring finger protein 187

increases expression

EXP

nefazodone results in increased expression of RNF187 mRNA

NCBI chr10:44,209,080...44,214,979
Ensembl chr10:44,202,332...44,215,470

G

ring finger protein 39

decreases expression

EXP

nefazodone results in decreased expression of RNF39 mRNA

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,610,026...1,612,323

G

ring finger protein 4

increases expression

EXP

nefazodone results in increased expression of RNF4 mRNA

NCBI chr14:80,625,864...80,647,138
Ensembl chr14:80,625,866...80,647,148

G

ring finger protein 7

increases expression

EXP

nefazodone results in increased expression of RNF7 mRNA

NCBI chr 8:105,918,395...105,927,643
Ensembl chr 8:105,918,395...105,927,405

G

ribonuclease/angiogenin inhibitor 1

increases expression

EXP

nefazodone results in increased expression of RNH1 mRNA

NCBI chr 1:205,698,882...205,711,348
Ensembl chr 1:205,698,882...205,711,582

G

RNA binding protein with serine rich domain 1

increases expression

EXP

nefazodone results in increased expression of RNPS1 mRNA

NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393

G

rogdi atypical leucine zipper

increases expression

EXP

nefazodone results in increased expression of ROGDI mRNA

NCBI chr10:11,074,288...11,078,907
Ensembl chr10:11,074,262...11,078,906

G

RAR-related orphan receptor A

decreases expression

EXP

nefazodone results in decreased expression of RORA mRNA

NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730

G

RAR-related orphan receptor C

decreases expression

EXP

nefazodone results in decreased expression of RORC mRNA

NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566

G

replication protein A1

decreases expression

EXP

nefazodone results in decreased expression of RPA1 mRNA

NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279

G

ribosomal protein L10A

increases expression

EXP

nefazodone results in increased expression of RPL10A mRNA

NCBI chr20:6,390,533...6,393,091
Ensembl chr20:6,390,179...6,393,091

G

ribosomal protein L12, pseudogene 1

increases expression

EXP

nefazodone results in increased expression of RPL12A-PS1 mRNA

NCBI chr 7:52,366,726...52,367,448

G

ribosomal protein L15

increases expression

EXP

nefazodone results in increased expression of RPL15 mRNA

NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308

G

ribosomal protein L17

increases expression

EXP

nefazodone results in increased expression of RPL17 mRNA

NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638
Ensembl chr18:111,722,010...111,722,638

G

ribosomal protein L18

increases expression

EXP

nefazodone results in increased expression of RPL18 mRNA

NCBI chr 1:105,325,269...105,327,911
Ensembl chr 1:105,325,250...105,327,910

G

ribosomal protein L18A

increases expression

EXP

nefazodone results in increased expression of RPL18A mRNA

NCBI chr16:18,576,467...18,578,653
Ensembl chr 1:70,166,729...70,167,654
Ensembl chr16:70,166,729...70,167,654

G

ribosomal protein L22 like 1

increases expression

EXP

nefazodone results in increased expression of RPL22L1 mRNA

NCBI chr 2:113,683,196...113,685,132
Ensembl chr 2:113,683,196...113,685,132

G

ribosomal protein L23

increases expression

EXP

nefazodone results in increased expression of RPL23 mRNA

NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214

G

ribosomal protein L3

increases expression

EXP

nefazodone results in increased expression of RPL3 mRNA

NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990

G

ribosomal protein L36A

increases expression

EXP

nefazodone results in increased expression of RPL36A mRNA

NCBI chr X:102,058,573...102,062,162
Ensembl chr20:22,034,086...22,034,406

G

ribosomal protein L7-like 1

increases expression

EXP

nefazodone results in increased expression of RPL7L1 mRNA

NCBI chr 9:21,695,718...21,703,736
Ensembl chr 9:21,695,707...21,703,735

G

ribosomal protein L8

increases expression

EXP

nefazodone results in increased expression of RPL8 mRNA

NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:110,506,800...110,509,103
Ensembl chr 3:110,506,800...110,509,103

G

ribosomal protein L9

increases expression

EXP

nefazodone results in increased expression of RPL9 mRNA

NCBI chr14:43,247,536...43,250,784
Ensembl chr14:43,247,588...43,250,782
Ensembl chr 1:43,247,588...43,250,782

G

ribosomal protein lateral stalk subunit P2

increases expression

EXP

nefazodone results in increased expression of RPLP2 mRNA

NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191

G

ribonuclease P/MRP subunit p21

decreases expression

EXP

nefazodone results in decreased expression of RPP21 mRNA

NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,023,186...2,025,308

G

ribosomal protein S12

increases expression

EXP

nefazodone results in increased expression of RPS12 mRNA

NCBI chr 1:23,499,943...23,502,234
Ensembl chr 1:23,500,073...23,502,235

G

ribosomal protein S14

increases expression

EXP

nefazodone results in increased expression of RPS14 mRNA

NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091

G

ribosomal protein S15

increases expression

EXP

nefazodone results in increased expression of RPS15 mRNA

NCBI chr 7:10,066,572...10,068,167
Ensembl chr 7:10,066,677...10,068,123

G

ribosomal protein S16

increases expression

EXP

nefazodone results in increased expression of RPS16 mRNA

NCBI chr 1:92,770,658...92,773,603
Ensembl chr19:56,922,246...56,923,020
Ensembl chr 1:56,922,246...56,923,020

G

ribosomal protein S17

increases expression

EXP

nefazodone results in increased expression of RPS17 mRNA

NCBI chr 1:144,705,150...144,707,736
Ensembl chr 1:144,705,149...144,707,734
Ensembl chr 8:144,705,149...144,707,734

G

ribosomal protein S2

increases expression

EXP

nefazodone results in increased expression of RPS2 mRNA

NCBI chr10:14,251,841...14,253,697
Ensembl chr10:14,251,380...14,253,695

G

ribosomal protein S2, pseudogene 38

increases expression

EXP

nefazodone results in increased expression of RPS2-PS38 mRNA

NCBI chr11:38,421,728...38,422,600

G

ribosomal protein S20

increases expression

EXP

nefazodone results in increased expression of RPS20 mRNA

NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621
Ensembl chr 9:42,839,965...43,095,621
Ensembl chr 5:42,839,965...43,095,621

G

ribosomal protein S21, pseudogene 1

increases expression

EXP

nefazodone results in increased expression of RPS21 mRNA

NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:158,670,116...158,670,490

G

ribosomal protein S27a

increases expression

EXP

nefazodone results in increased expression of RPS27A mRNA

NCBI chr14:107,486,664...107,488,941
Ensembl chr 5:138,465,088...138,466,080
Ensembl chr14:138,465,088...138,466,080
Ensembl chr 5:138,465,088...138,466,080

G

ribosomal protein S3

increases expression

EXP

nefazodone results in increased expression of RPS3 mRNA

NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776

G

ribosomal protein S5

increases expression

EXP

nefazodone results in increased expression of RPS5 mRNA

NCBI chr 1:82,610,965...82,615,262
Ensembl chr 1:82,610,965...82,615,262

G

ribosomal protein S6

increases expression

EXP

nefazodone results in increased expression of RPS6 mRNA

NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566

G

ribosomal protein S9

increases expression

EXP

nefazodone results in increased expression of RPS9 mRNA

NCBI chr 1:74,427,084...74,430,513
Ensembl chr 1:74,427,087...74,430,105

G

ribosomal protein SA

increases expression

EXP

nefazodone results in increased expression of RPSA mRNA

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737

G

Ras-related GTP binding C

increases expression

EXP

nefazodone results in increased expression of RRAGC mRNA

NCBI chr 5:141,433,014...141,452,546
Ensembl chr 5:141,433,040...141,452,548

G

RAS related 2

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RRAS2 mRNA

NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551

G

ribonucleotide reductase regulatory subunit M2

decreases expression

EXP

nefazodone results in decreased expression of RRM2 mRNA

NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370

G

RRN3 homolog, RNA polymerase I transcription factor

increases expression

EXP

nefazodone results in increased expression of RRN3 mRNA

NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,637,016...2,672,330

G

arginine and serine rich coiled-coil 2

decreases expression

EXP

nefazodone results in decreased expression of RSRC2 mRNA

NCBI chr12:38,500,709...38,520,715
Ensembl chr12:38,500,770...38,520,707

G

arginine and serine rich protein 1

decreases expression

EXP

nefazodone results in decreased expression of RSRP1 mRNA

NCBI chr 5:152,431,448...152,435,202
Ensembl chr 5:152,431,478...152,435,126

G

RT1 class Ib, locus S3

decreases expression

EXP

nefazodone results in decreased expression of RT1-S3 mRNA

NCBI chr20:2,675,463...2,680,229

G

RNA 2',3'-cyclic phosphate and 5'-OH ligase

increases expression

EXP

nefazodone results in increased expression of RTCB mRNA

NCBI chr 7:17,907,668...17,927,136
Ensembl chr 7:19,795,393...19,814,875

G

retrotransposon Gag like 8A

decreases expression

EXP

nefazodone results in decreased expression of RTL8B mRNA

NCBI chr X:138,436,824...138,438,037
Ensembl chr X:138,436,605...138,470,972

G

urinary protein 2

decreases expression

EXP

nefazodone results in decreased expression of RUP2 mRNA

NCBI chr 8:43,547,875...43,551,456
Ensembl chr 8:43,549,809...43,700,211

G

RuvB-like AAA ATPase 2

increases expression

EXP

nefazodone results in increased expression of RUVBL2 mRNA

NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720

G

RWD domain containing 4

increases expression

EXP

nefazodone results in increased expression of RWDD4 mRNA

NCBI chr16:44,714,698...44,733,090
Ensembl chr16:51,447,385...51,465,759

G

sphingosine-1-phosphate receptor 1

decreases expression

EXP

nefazodone results in decreased expression of S1PR1 mRNA

NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689

G

serum amyloid A4

decreases expression

EXP

nefazodone results in decreased expression of SAA4 mRNA

NCBI chr 1:106,383,856...106,388,158
Ensembl chr 1:106,383,856...106,387,354

G

spalt-like transcription factor 1

increases expression

EXP

nefazodone results in increased expression of SALL1 mRNA

NCBI chr19:34,179,316...34,196,278
Ensembl chr19:34,181,078...34,196,278

G

SAMM50 sorting and assembly machinery component

increases expression

EXP

nefazodone results in increased expression of SAMM50 mRNA

NCBI chr 7:117,197,460...117,221,668
Ensembl chr 7:117,197,381...117,224,581

G

Sin3A associated protein 18

increases expression

EXP

nefazodone results in increased expression of SAP18 mRNA

NCBI chr15:36,058,784...36,063,089
Ensembl chr10:87,156,914...87,158,257
Ensembl chr15:87,156,914...87,158,257

G

SAP30-like

increases expression

EXP

nefazodone results in increased expression of SAP30L mRNA

NCBI chr10:42,480,201...42,488,139
Ensembl chr10:42,480,201...42,488,139

G

secretion associated, Ras related GTPase 1B

increases expression

EXP

nefazodone results in increased expression of SAR1B mRNA

NCBI chr10:36,525,365...36,555,009
Ensembl chr10:36,519,384...36,555,005

G

sarcosine dehydrogenase

decreases expression

EXP

nefazodone results in decreased expression of SARDH mRNA

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137

G

seryl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of SARS1 mRNA

NCBI chr 2:198,753,673...198,769,411
Ensembl chr 2:198,753,675...198,769,365

G

spermidine/spermine N1-acetyl transferase 1

decreases expression

EXP

nefazodone results in decreased expression of SAT1 mRNA

NCBI chr X:44,008,089...44,011,376
Ensembl chr X:44,006,781...44,011,374

G

secretory carrier membrane protein 1

increases expression

EXP

nefazodone results in increased expression of SCAMP1 mRNA

NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742

G

secretory carrier membrane protein 4

increases expression

EXP

nefazodone results in increased expression of SCAMP4 mRNA

NCBI chr 7:9,752,193...9,764,614
Ensembl chr 7:9,752,193...9,778,736

G

scavenger receptor class B, member 1

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SCARB1 mRNA

NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980

G

scavenger receptor class B, member 2

increases expression

EXP

nefazodone results in increased expression of SCARB2 mRNA

NCBI chr14:15,842,583...15,894,123
Ensembl chr14:15,842,515...15,896,671

G

saccharopine dehydrogenase (putative)

increases expression

EXP

nefazodone results in increased expression of SCCPDH mRNA

NCBI chr13:93,932,086...93,953,840
Ensembl chr13:93,912,395...93,954,192

G

stearoyl-CoA desaturase

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of SCD1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SCD mRNA

PMID:24136188 PMID:33819548

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

sodium voltage-gated channel alpha subunit 5

affects activity

ISO

nefazodone affects the activity of SCN5A protein

NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:128,098,613...128,196,470

G

sterol carrier protein 2

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of SCP2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SCP2 mRNA

PMID:24136188 PMID:33819548

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043

G

syndecan 2

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of SDC2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SDC2 mRNA

PMID:24136188 PMID:33819548

NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294

G

succinate dehydrogenase complex subunit C

increases expression

EXP

nefazodone results in increased expression of SDHC mRNA

NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044

G

short chain dehydrogenase/reductase family 42E, member 1

increases expression

EXP

nefazodone results in increased expression of SDR42E1 mRNA

NCBI chr19:62,624,130...62,636,652
Ensembl chr19:62,624,150...62,636,756

G

serine dehydratase

decreases expression

EXP

nefazodone results in decreased expression of SDS mRNA

NCBI chr12:41,743,796...41,751,108
Ensembl chr12:41,743,799...41,748,773

G

Sec23 homolog A, COPII coat complex component

increases expression

EXP

nefazodone results in increased expression of SEC23A mRNA

NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:82,394,863...82,440,904

G

Sec23 homolog B, COPII coat complex component

increases expression

EXP

nefazodone results in increased expression of SEC23B mRNA

NCBI chr 3:152,392,340...152,434,813
Ensembl chr 3:152,392,308...152,434,800

G

SEC24 homolog D, COPII coat complex component

increases expression

EXP

nefazodone results in increased expression of SEC24D mRNA

NCBI chr 2:214,103,138...214,211,155
Ensembl chr 2:214,103,190...214,211,144

G

SEC62 homolog, preprotein translocation factor

decreases expression

EXP

nefazodone results in decreased expression of SEC62 mRNA

NCBI chr 2:114,499,317...114,526,705
Ensembl chr 2:114,499,317...114,530,321

G

SEC63 homolog, protein translocation regulator

decreases expression

EXP

nefazodone results in decreased expression of SEC63 mRNA

NCBI chr20:47,827,291...47,896,248
Ensembl chr20:47,827,291...47,896,248

G

secreted and transmembrane 1B

decreases expression

EXP

nefazodone results in decreased expression of SECTM1B mRNA

NCBI chr10:106,822,397...106,832,105
Ensembl chr10:106,822,397...106,832,104

G

selenium binding protein 1

increases expression

EXP

nefazodone results in increased expression of SELENBP1 mRNA

NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295

G

small EDRK-rich factor 2

decreases expression

EXP

nefazodone results in decreased expression of SERF2 mRNA

NCBI chr 3:128,880,681...128,884,457
Ensembl chr 3:128,880,681...128,884,457

G

stress-associated endoplasmic reticulum protein 1

increases expression

EXP

nefazodone results in increased expression of SERP1 mRNA

NCBI chr 2:144,907,204...144,911,187
Ensembl chr 2:144,907,205...144,911,187

G

serpin family A member 11

decreases expression

EXP

nefazodone results in decreased expression of SERPINA11 mRNA

NCBI chr 6:128,668,030...128,677,476
Ensembl chr 6:128,668,034...128,677,454

G

serine (or cysteine) proteinase inhibitor, clade A, member 3C

decreases expression

EXP

nefazodone results in decreased expression of SERPINA3C mRNA

NCBI chr 6:129,007,578...129,014,988
Ensembl chr 6:128,829,577...129,014,971

G

serpin family A member 3N

decreases expression

EXP

nefazodone results in decreased expression of SERPINA3N mRNA

NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415

G

serpin family A member 4

decreases expression

EXP

nefazodone results in decreased expression of SERPINA4 mRNA

NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028

G

serpin family A member 6

decreases expression

EXP

nefazodone results in decreased expression of SERPINA6 mRNA

NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:128,544,831...128,555,139

G

serpin family B member 9

decreases expression

EXP

nefazodone results in decreased expression of SERPINB9 mRNA

NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974

G

serpin family D member 1

decreases expression

EXP

nefazodone results in decreased expression of SERPIND1 mRNA

NCBI chr11:97,168,753...97,179,830
Ensembl chr11:97,168,754...97,179,755

G

serpin family E member 1

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA
nefazodone results in increased expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

serpin family F member 2

decreases expression

EXP

nefazodone results in decreased expression of SERPINF2 mRNA

NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996

G

serpin family G member 1

decreases expression

EXP

nefazodone results in decreased expression of SERPING1 mRNA

NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717

G

sestrin 2

decreases expression

EXP

nefazodone results in decreased expression of SESN2 mRNA

NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255

G

Set nuclear proto-oncogene

increases expression

EXP

nefazodone results in increased expression of SET mRNA

NCBI chr 3:33,732,319...33,743,433

G

SET domain containing 4

increases expression

EXP

nefazodone results in increased expression of SETD4 mRNA

NCBI chr11:46,315,340...46,344,024
Ensembl chr11:46,323,895...46,344,024

G

SET domain containing 6, protein lysine methyltransferase

increases expression

EXP

nefazodone results in increased expression of SETD6 mRNA

NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515

G

seizure related 6 homolog

decreases expression

EXP

nefazodone results in decreased expression of SEZ6 mRNA

NCBI chr10:63,317,065...63,366,733
Ensembl chr10:63,316,953...63,366,723

G

splicing factor 3B subunit 4

increases expression

EXP

nefazodone results in increased expression of SF3B4 mRNA

NCBI chr 2:186,421,667...186,426,419
Ensembl chr 2:186,421,636...186,426,833

G

splicing factor 3b, subunit 5

increases expression

EXP

nefazodone results in increased expression of SF3B5 mRNA

NCBI chr 1:9,177,189...9,177,901
Ensembl chr 1:9,177,098...9,177,900

G

splicing factor proline and glutamine rich

increases expression

EXP

nefazodone results in increased expression of SFPQ mRNA

NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926

G

sideroflexin 1

increases expression

EXP

nefazodone results in increased expression of SFXN1 mRNA

NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456

G

SAGA complex associated factor 29

increases expression

EXP

nefazodone results in increased expression of SGF29 mRNA

NCBI chr 1:190,668,803...190,702,500
Ensembl chr 1:190,669,028...190,717,906

G

serum/glucocorticoid regulated kinase 1

decreases expression

EXP

nefazodone results in decreased expression of SGK1 mRNA

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231

G

sphingosine-1-phosphate phosphatase 1

increases expression

EXP

nefazodone results in increased expression of SGPP1 mRNA

NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259

G

SH2 domain containing 4A

decreases expression

EXP

nefazodone results in decreased expression of SH2D4A mRNA

NCBI chr16:26,106,721...26,176,069
Ensembl chr16:26,106,730...26,175,974

G

SH3 domain binding glutamate rich protein like

decreases expression

EXP

nefazodone results in decreased expression of SH3BGRL mRNA

NCBI chr X:78,242,704...78,343,633
Ensembl chr X:78,242,405...78,343,634

G

SH3 domain -containing GRB2-like endophilin B1

multiple interactions
increases expression

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA
nefazodone results in increased expression of SH3GLB1 mRNA

NCBI chr 2:236,411,194...236,445,225
Ensembl chr 2:236,410,436...236,445,140

G

SHC adaptor protein 1

increases expression

EXP

nefazodone results in increased expression of SHC1 mRNA

NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914

G

serine hydroxymethyltransferase 1

increases expression

EXP

nefazodone results in increased expression of SHMT1 mRNA

NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,960,434...45,997,326

G

SIN3 transcription regulator family member B

increases expression

EXP

nefazodone results in increased expression of SIN3B mRNA

NCBI chr16:17,157,352...17,194,051
Ensembl chr16:17,157,352...17,270,664

G

SKI8 subunit of superkiller complex

increases expression

EXP

nefazodone results in increased expression of SKIC8 mRNA

NCBI chr 8:63,999,669...64,016,959
Ensembl chr 8:63,999,671...64,016,846

G

S-phase kinase-associated protein 1

increases expression

EXP

nefazodone results in increased expression of SKP1 mRNA

NCBI chr10:36,898,670...36,917,828
Ensembl chr10:36,903,078...36,918,308

G

solute carrier family 10 member 1

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of SLC10A1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SLC10A1 mRNA

PMID:24136188 PMID:32152650

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944

G

solute carrier family 10, member 7

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of SLC10A7 mRNA

NCBI chr19:46,087,440...46,311,753
Ensembl chr19:46,049,631...46,311,753

G

solute carrier family 12 member 2

increases expression

EXP

nefazodone results in increased expression of SLC12A2 mRNA

NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470

G

solute carrier family 16 member 7

increases expression

EXP

nefazodone results in increased expression of SLC16A7 mRNA

NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386

G

solute carrier family 17 member 1

increases expression

EXP

nefazodone results in increased expression of SLC17A1 mRNA

NCBI chr17:41,647,332...41,683,078
Ensembl chr17:41,649,919...41,681,174

G

solute carrier family 17, member 2

decreases expression

EXP

nefazodone results in decreased expression of SLC17A2 mRNA

NCBI chr17:41,748,195...41,767,601
Ensembl chr17:41,748,195...41,764,180

G

solute carrier family 17 member 3

increases expression

EXP

nefazodone results in increased expression of SLC17A3 mRNA

NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,698,680...41,723,329

G

solute carrier family 18 member B1

increases expression

EXP

nefazodone results in increased expression of SLC18B1 mRNA

NCBI chr 1:23,447,462...23,490,043
Ensembl chr 1:23,447,462...23,489,962

G

solute carrier family 19 member 2

decreases expression

EXP

nefazodone results in decreased expression of SLC19A2 mRNA

NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315

G

solute carrier family 20 member 1

increases expression

EXP

nefazodone results in increased expression of SLC20A1 mRNA

NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249

G

solute carrier family 22 member 1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of SLC22A1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SLC22A1 mRNA

PMID:24136188 PMID:33819548

NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436

G

solute carrier family 22, member 18

increases expression

EXP

nefazodone results in increased expression of SLC22A18 mRNA

NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:208,101,136...208,124,380

G

solute carrier family 22 member 2

multiple interactions

ISO

nefazodone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]

NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019

G

solute carrier family 22 member 5

increases expression

EXP

nefazodone results in increased expression of SLC22A5 mRNA

NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077

G

solute carrier family 22 member 7

decreases expression

EXP

nefazodone results in decreased expression of SLC22A7 mRNA

NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681

G

solute carrier family 22 member 8

decreases expression

EXP

nefazodone results in decreased expression of SLC22A8 mRNA

NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588

G

solute carrier family 25 member 1

decreases expression

EXP

nefazodone results in decreased expression of SLC25A1 mRNA

NCBI chr11:96,560,054...96,563,071
Ensembl chr11:96,560,041...96,565,052

G

solute carrier family 25 member 17

increases expression

EXP

nefazodone results in increased expression of SLC25A17 mRNA

NCBI chr 7:114,724,533...114,767,163
Ensembl chr 7:114,724,533...114,767,345

G

solute carrier family 25 member 20

increases expression

EXP

nefazodone results in increased expression of SLC25A20 mRNA

NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027

G

solute carrier family 25 member 23

decreases expression

EXP

nefazodone results in decreased expression of SLC25A23 mRNA

NCBI chr 9:1,969,633...1,985,365
Ensembl chr 9:1,969,357...1,985,365

G

solute carrier family 25 member 25

decreases expression

EXP

nefazodone results in decreased expression of SLC25A25 mRNA

NCBI chr 3:36,106,448...36,139,812
Ensembl chr 3:36,106,449...36,140,011

G

solute carrier family 25 member 3

increases expression

EXP

nefazodone results in increased expression of SLC25A3 mRNA

NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309

G

solute carrier family 25, member 30

decreases expression

EXP

nefazodone results in decreased expression of SLC25A30 mRNA

NCBI chr15:57,486,346...57,508,981
Ensembl chr15:57,486,350...57,502,690

G

solute carrier family 25, member 39

increases expression

EXP

nefazodone results in increased expression of SLC25A39 mRNA

NCBI chr10:87,862,630...87,867,626
Ensembl chr10:87,862,631...87,866,973

G

solute carrier family 26 member 8

increases expression

EXP

nefazodone results in increased expression of SLC26A8 mRNA

NCBI chr20:6,687,207...6,751,184
Ensembl chr20:6,699,445...6,751,184

G

solute carrier family 28 member 2

decreases expression

EXP

nefazodone results in decreased expression of SLC28A2 mRNA

NCBI chr 3:129,778,425...129,841,292
Ensembl chr 3:129,807,537...129,841,291

G

solute carrier family 29 member 1

decreases expression

EXP

nefazodone results in decreased expression of SLC29A1 mRNA

NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620

G

solute carrier family 2 member 2

decreases expression

EXP

nefazodone results in decreased expression of SLC2A2 mRNA

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467

G

solute carrier family 30 member 1

increases expression

EXP

nefazodone results in increased expression of SLC30A1 mRNA

NCBI chr13:106,022,019...106,025,892
Ensembl chr13:106,022,019...106,025,892

G

solute carrier family 30 member 5

increases expression

EXP

nefazodone results in increased expression of SLC30A5 mRNA

NCBI chr 2:33,679,800...33,710,025
Ensembl chr 2:33,679,800...33,712,596

G

solute carrier family 33 member 1

increases expression

EXP

nefazodone results in increased expression of SLC33A1 mRNA

NCBI chr 2:150,565,327...150,587,700
Ensembl chr 2:150,565,328...150,587,416

G

solute carrier family 34 member 1

increases expression

EXP

nefazodone results in increased expression of SLC34A1 mRNA

NCBI chr17:9,224,010...9,238,983
Ensembl chr17:9,224,010...9,238,983

G

solute carrier family 34 member 2

decreases expression

EXP

nefazodone results in decreased expression of SLC34A2 mRNA

NCBI chr14:62,123,313...62,153,020
Ensembl chr14:62,123,316...62,143,360

G

solute carrier family 35, member B1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of SLC35B1 mRNA

NCBI chr10:80,327,921...80,335,279
Ensembl chr10:80,824,696...80,832,045

G

solute carrier family 35, member E3

increases expression

EXP

nefazodone results in increased expression of SLC35E3 mRNA

NCBI chr 7:53,337,091...53,350,152
Ensembl chr 7:55,219,998...55,236,035

G

solute carrier family 39 member 8

decreases expression

EXP

nefazodone results in decreased expression of SLC39A8 mRNA

NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667

G

solute carrier family 3 member 2

increases expression

EXP

nefazodone results in increased expression of SLC3A2 mRNA

NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064

G

solute carrier family 40 member 1

increases expression

EXP

nefazodone results in increased expression of SLC40A1 mRNA

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460

G

solute carrier family 43 member 1

decreases expression

EXP

nefazodone results in decreased expression of SLC43A1 mRNA

NCBI chr 3:90,327,250...90,353,438
Ensembl chr 3:90,327,149...90,353,438

G

solute carrier family 46 member 1

decreases expression

EXP

nefazodone results in decreased expression of SLC46A1 mRNA

NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869

G

solute carrier family 48 member 1

increases expression

EXP

nefazodone results in increased expression of SLC48A1 mRNA

NCBI chr 7:130,794,233...130,802,119
Ensembl chr 7:130,794,245...130,803,022

G

solute carrier family 4 member 2

increases expression

EXP

nefazodone results in increased expression of SLC4A2 mRNA

NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:11,628,862...11,645,402

G

SLC51 subunit beta

multiple interactions

ISO

[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SLC51B mRNA

NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:74,827,047...74,835,109

G

solute carrier family 66 member 2

decreases expression

EXP

nefazodone results in decreased expression of SLC66A2 mRNA

NCBI chr18:75,976,000...76,014,651
Ensembl chr18:75,977,458...76,014,651

G

solute carrier family 6 member 12

decreases expression

EXP

nefazodone results in decreased expression of SLC6A12 mRNA

NCBI chr 4:156,257,518...156,275,870
Ensembl chr 4:156,254,208...156,275,879

G

solute carrier family 6 member 6

decreases expression

EXP

nefazodone results in decreased expression of SLC6A6 mRNA

NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032

G

solute carrier family 6 member 9

increases expression

EXP

nefazodone results in increased expression of SLC6A9 mRNA

NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172

G

solute carrier organic anion transporter family, member 1a4

increases expression

EXP

nefazodone results in increased expression of SLCO1A2 mRNA

NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816

G

solute carrier organic anion transporter family, member 2a1

decreases expression

EXP

nefazodone results in decreased expression of SLCO2A1 mRNA

NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:112,467,160...112,551,921

G

schlafen 3

decreases expression

EXP

nefazodone results in decreased expression of SLFN3 mRNA

NCBI chr10:68,020,482...68,060,248

G

secretory leukocyte peptidase inhibitor

increases expression

ISO

nefazodone results in increased expression of SLPI mRNA

NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822

G

SAFB-like, transcription modulator

increases expression

EXP

nefazodone results in increased expression of SLTM mRNA

NCBI chr 8:80,096,555...80,142,668
Ensembl chr 8:80,097,652...80,142,671

G

small cell adhesion glycoprotein

decreases expression

EXP

nefazodone results in decreased expression of SMAGP mRNA

NCBI chr 7:133,599,043...133,617,492
Ensembl chr 7:133,599,043...133,616,642

G

SWI/SNF related BAF chromatin remodeling complex subunit B1

increases expression

EXP

nefazodone results in increased expression of SMARCB1 mRNA

NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,740,943...12,763,055

G

structural maintenance of chromosomes 6

decreases expression

EXP

nefazodone results in decreased expression of SMC6 mRNA

NCBI chr 6:39,697,810...39,752,275
Ensembl chr 6:39,697,811...39,752,279

G

small integral membrane protein 26

increases expression

EXP

nefazodone results in increased expression of SMIM26 mRNA

NCBI chr 3:152,443,397...152,445,102
Ensembl chr 3:152,443,579...152,445,447

G

SPARC related modular calcium binding 1

decreases expression

EXP

nefazodone results in decreased expression of SMOC1 mRNA

NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956

G

synaptosome associated protein 29

increases expression

EXP

nefazodone results in increased expression of SNAP29 mRNA

NCBI chr11:97,082,721...97,113,195
Ensembl chr11:97,082,739...97,113,195

G

small nuclear ribonucleoprotein U11/U12 subunit 25

increases expression

EXP

nefazodone results in increased expression of SNRNP25 mRNA

NCBI chr10:15,924,932...15,928,279
Ensembl chr10:15,924,940...15,928,252

G

small nuclear ribonucleoprotein U1 subunit 70

decreases expression

EXP

nefazodone results in decreased expression of SNRNP70 mRNA

NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:104,992,442...105,012,851

G

small nuclear ribonucleoprotein polypeptides B and B1

increases expression

EXP

nefazodone results in increased expression of SNRPB mRNA

NCBI chr 3:137,824,870...137,832,479
Ensembl chr 3:137,824,683...137,832,515

G

small nuclear ribonucleoprotein polypeptide C

increases expression

EXP

nefazodone results in increased expression of SNRPC mRNA

NCBI chr20:5,890,229...5,908,410
Ensembl chr20:5,890,229...5,908,410

G

small nuclear ribonucleoprotein D3 polypeptide

increases expression

EXP

nefazodone results in increased expression of SNRPD3 mRNA

NCBI chr20:13,129,555...13,145,100
Ensembl chr20:13,109,294...13,145,763

G

small nuclear ribonucleoprotein polypeptide G

increases expression

EXP

nefazodone results in increased expression of SNRPG mRNA

NCBI chr 4:120,369,676...120,377,263
Ensembl chr 4:120,369,685...120,377,261
Ensembl chr X:120,369,685...120,377,261

G

small nuclear ribonucleoprotein 13

increases expression

EXP

nefazodone results in increased expression of SNU13 mRNA

NCBI chr 7:115,445,415...115,451,008
Ensembl chr 1:269,702,002...269,703,004
Ensembl chr 7:269,702,002...269,703,004

G

sorting nexin 2

increases expression

EXP

nefazodone results in increased expression of SNX2 mRNA

NCBI chr18:48,800,594...48,842,158
Ensembl chr18:48,800,583...48,842,474

G

sorting nexin 24

decreases expression

EXP

nefazodone results in decreased expression of SNX24 mRNA

NCBI chr18:48,869,804...49,024,352
Ensembl chr18:48,869,882...49,024,350

G

suppressor of cytokine signaling 2

decreases expression

EXP

nefazodone results in decreased expression of SOCS2 mRNA

NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423

G

superoxide dismutase 2

increases expression
decreases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of SOD2 mRNA
nefazodone results in decreased expression of SOD2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SOD2 mRNA

PMID:24136188 PMID:32152650

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

sorbitol dehydrogenase

increases expression

EXP

nefazodone results in increased expression of SORD mRNA

NCBI chr 3:129,638,282...129,669,727
Ensembl chr 3:129,638,302...129,686,100

G

sortilin related receptor 1

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SORL1 mRNA

NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:51,238,722...51,401,446

G

secreted protein acidic and cysteine rich

decreases expression

EXP

nefazodone results in decreased expression of SPARC mRNA

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268

G

SPG21 abhydrolase domain containing, maspardin

increases expression

EXP

nefazodone results in increased expression of SPG21 mRNA

NCBI chr 8:74,876,136...74,903,676
Ensembl chr 8:74,876,136...74,903,676

G

sphingosine kinase 2

increases expression

EXP

nefazodone results in increased expression of SPHK2 mRNA

NCBI chr 1:105,317,332...105,324,985
Ensembl chr 1:105,317,333...105,321,637

G

serine peptidase inhibitor, Kazal type 1

decreases expression

EXP

nefazodone results in decreased expression of SPINK1 mRNA

NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545

G

SPRY domain containing 4

increases expression

EXP

nefazodone results in increased expression of SPRYD4 mRNA

NCBI chr 7:1,217,984...1,222,231
Ensembl chr 7:1,218,122...1,219,942

G

SPRY domain containing 7

increases expression

EXP

nefazodone results in increased expression of SPRYD7 mRNA

NCBI chr15:39,883,237...39,903,770
Ensembl chr15:39,883,238...39,903,674

G

spectrin, alpha, non-erythrocytic 1

increases expression

EXP

nefazodone results in increased expression of SPTAN1 mRNA

NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889

G

serine palmitoyltransferase, small subunit A

decreases expression

EXP

nefazodone results in decreased expression of SPTSSA mRNA

NCBI chr 6:77,879,931...77,891,344
Ensembl chr 6:77,879,941...77,891,403

G

sequestosome 1

increases expression
multiple interactions

EXP
ISO

nefazodone results in increased expression of SQSTM1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA

PMID:24136188 PMID:32152650

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750

G

steroid 5 alpha-reductase 1

decreases expression

EXP

nefazodone results in decreased expression of SRD5A1 mRNA

NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903

G

sterol regulatory element binding transcription factor 1

decreases expression
multiple interactions

EXP
ISO

nefazodone results in decreased expression of SREBF1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SREBF1 mRNA

PMID:24136188 PMID:33819548

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

serglycin

decreases expression

EXP

nefazodone results in decreased expression of SRGN mRNA

NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327

G

spermidine synthase

increases expression

EXP

nefazodone results in increased expression of SRM mRNA

NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705

G

signal recognition particle 72

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of SRP72 mRNA

NCBI chr14:31,522,424...31,549,978
Ensembl chr14:31,522,963...31,550,151

G

serine racemase

decreases expression

EXP

nefazodone results in decreased expression of SRR mRNA

NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100

G

serrate, RNA effector molecule

increases expression

EXP

nefazodone results in increased expression of SRRT mRNA

NCBI chr12:25,027,883...25,042,847
Ensembl chr12:25,029,334...25,042,845

G

serine and arginine rich splicing factor 11

decreases expression

EXP

nefazodone results in decreased expression of SRSF11 mRNA

NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499

G

serine and arginine rich splicing factor 4

increases expression

EXP

nefazodone results in increased expression of SRSF4 mRNA

NCBI chr 5:149,345,538...149,373,309
Ensembl chr 5:149,345,422...149,374,609

G

sulfiredoxin 1

increases expression

EXP

nefazodone results in increased expression of SRXN1 mRNA

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765

G

single stranded DNA binding protein 1

increases expression

EXP

nefazodone results in increased expression of SSBP1 mRNA

NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700

G

SSX family member 2 interacting protein

decreases expression

EXP

nefazodone results in decreased expression of SSX2IP mRNA

NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017

G

ST13, Hsp70 interacting protein

increases expression

EXP

nefazodone results in increased expression of ST13 mRNA

NCBI chr 7:114,769,758...114,805,877
Ensembl chr 7:114,769,759...114,805,941

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

decreases expression

EXP

nefazodone results in decreased expression of ST6GAL1 mRNA

NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415

G

SH3 and cysteine rich domain 3

decreases expression

EXP

nefazodone results in decreased expression of STAC3 mRNA

NCBI chr 7:65,227,151...65,235,884
Ensembl chr 7:65,228,352...65,235,878

G

STAG1 cohesin complex component

decreases expression

EXP

nefazodone results in decreased expression of STAG1 mRNA

NCBI chr 8:110,057,981...110,443,666
Ensembl chr 8:110,058,056...110,443,665

G

STARD3 N-terminal like

increases expression

EXP

nefazodone results in increased expression of STARD3NL mRNA

NCBI chr17:50,278,859...50,312,864
Ensembl chr17:50,278,894...50,312,866

G

signal transducer and activator of transcription 2

decreases expression

EXP

nefazodone results in decreased expression of STAT2 mRNA

NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459

G

starch binding domain 1

increases expression

EXP

nefazodone results in increased expression of STBD1 mRNA

NCBI chr14:15,754,769...15,758,174
Ensembl chr14:15,754,644...15,761,659

G

STEAP3 metalloreductase

decreases expression

EXP

nefazodone results in decreased expression of STEAP3 mRNA

NCBI chr13:33,904,710...33,950,100
Ensembl chr13:33,904,710...33,950,080

G

STEAP4 metalloreductase

decreases expression

EXP

nefazodone results in decreased expression of STEAP4 mRNA

NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:27,009,584...27,067,105

G

stress-induced phosphoprotein 1

increases expression

EXP

nefazodone results in increased expression of STIP1 mRNA

NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654

G

serine/threonine kinase 24

increases expression

EXP

nefazodone results in increased expression of STK24 mRNA

NCBI chr15:104,770,556...104,866,524
Ensembl chr15:104,773,569...104,865,975

G

stomatin like 2

increases expression

EXP

nefazodone results in increased expression of STOML2 mRNA

NCBI chr 5:62,052,042...62,055,639
Ensembl chr 5:62,052,045...62,055,670

G

serine/threonine kinase receptor associated protein

increases expression

EXP

nefazodone results in increased expression of STRAP mRNA

NCBI chr 4:172,377,325...172,391,573
Ensembl chr 4:172,377,305...172,392,436

G

syntaxin 12

increases expression

EXP

nefazodone results in increased expression of STX12 mRNA

NCBI chr 5:150,347,554...150,376,426
Ensembl chr 5:150,334,836...150,376,346

G

syntaxin 7

decreases expression

EXP

nefazodone results in decreased expression of STX7 mRNA

NCBI chr 1:23,016,330...23,056,579
Ensembl chr 1:23,016,336...23,056,465

G

sulfatase 2

decreases expression

EXP

nefazodone results in decreased expression of SULF2 mRNA

NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651

G

sulfotransferase family 1B member 1

increases expression

EXP

nefazodone results in increased expression of SULT1B1 mRNA

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549

G

sulfotransferase family 1C member 2A

decreases expression

EXP

nefazodone results in decreased expression of SULT1C2A mRNA

NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:7,066,905...7,244,132

G

sulfotransferase family 1C member 3

decreases expression

EXP

nefazodone results in decreased expression of SULT1C3 mRNA

NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295

G

sulfotransferase family 2A member 1

decreases expression
multiple interactions

ISO

nefazodone results in decreased expression of SULT2A1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SULT2A1 mRNA

NCBI chr 1:84,582,011...84,639,001

G

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6

increases expression

EXP

nefazodone results in increased expression of SULT2A6 mRNA

NCBI chr 1:84,046,685...84,097,808
Ensembl chr 1:84,046,685...84,097,808

G

sulfatase modifying factor 2

increases expression

EXP

nefazodone results in increased expression of SUMF2 mRNA

NCBI chr12:32,489,671...32,507,941
Ensembl chr12:32,489,671...32,507,928

G

Sad1 and UNC84 domain containing 2

increases expression

EXP

nefazodone results in increased expression of SUN2 mRNA

NCBI chr 7:113,155,766...113,172,950
Ensembl chr 7:113,155,766...113,172,940

G

sulfite oxidase

decreases expression

EXP

nefazodone results in decreased expression of SUOX mRNA

NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,687,666...1,690,235

G

supervillin

decreases expression

EXP

nefazodone results in decreased expression of SVIL mRNA

NCBI chr17:57,343,910...57,539,508
Ensembl chr17:57,343,910...57,462,660

G

SWI5 homologous recombination repair protein

increases expression

EXP

nefazodone results in increased expression of SWI5 mRNA

NCBI chr 3:35,972,436...35,981,658
Ensembl chr 3:35,972,436...35,981,554

G

synaptotagmin binding, cytoplasmic RNA interacting protein

increases expression

EXP

nefazodone results in increased expression of SYNCRIP mRNA

NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:98,282,358...98,315,386

G

spectrin repeat containing nuclear envelope protein 2

decreases expression

EXP

nefazodone results in decreased expression of SYNE2 mRNA

NCBI chr 6:100,272,729...100,586,364
Ensembl chr 6:100,272,729...100,583,723

G

synaptogyrin 2

increases expression

EXP

nefazodone results in increased expression of SYNGR2 mRNA

NCBI chr10:103,528,599...103,533,167
Ensembl chr10:103,528,607...103,533,162

G

synaptojanin 2 binding protein

decreases expression

EXP

nefazodone results in decreased expression of SYNJ2BP mRNA

NCBI chr 6:106,920,970...106,958,653
Ensembl chr 6:106,920,970...106,966,543

G

synergin, gamma

decreases expression

EXP

nefazodone results in decreased expression of SYNRG mRNA

NCBI chr10:69,346,154...69,428,714
Ensembl chr10:69,322,114...69,428,714

G

TATA-box binding protein associated factor 9

increases expression

EXP

nefazodone results in increased expression of TAF9 mRNA

NCBI chr 2:33,528,388...33,532,395
Ensembl chr 2:33,531,368...33,536,078

G

TAR DNA binding protein

increases expression

EXP

nefazodone results in increased expression of TARDBP mRNA

NCBI chr 5:164,330,452...164,348,435
Ensembl chr 5:164,334,924...164,345,204

G

TatD DNase domain containing 2

increases expression

EXP

nefazodone results in increased expression of TATDN2 mRNA

NCBI chr 4:148,400,454...148,416,501
Ensembl chr 4:148,400,492...148,416,501

G

TBC1 domain family, member 15

increases expression

EXP

nefazodone results in increased expression of TBC1D15 mRNA

NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303

G

TBC1 domain family, member 17

increases expression

EXP

nefazodone results in increased expression of TBC1D17 mRNA

NCBI chr 1:104,461,266...104,469,615
Ensembl chr 1:104,461,267...104,469,489

G

TBC1 domain family, member 8

decreases expression

EXP

nefazodone results in decreased expression of TBC1D8 mRNA

NCBI chr 9:49,147,109...49,257,140
Ensembl chr 9:49,147,109...49,257,118

G

tubulin folding cofactor B

increases expression

EXP

nefazodone results in increased expression of TBCB mRNA

NCBI chr 1:94,605,100...94,610,949
Ensembl chr 1:94,605,101...94,610,949

G

tubulin folding cofactor E

increases expression

EXP

nefazodone results in increased expression of TBCE mRNA

NCBI chr17:55,983,627...56,031,578
Ensembl chr17:55,985,707...56,032,302

G

TANK-binding kinase 1

increases expression

EXP

nefazodone results in increased expression of TBK1 mRNA

NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:58,963,325...58,996,357

G

transcription elongation factor A1

increases expression

EXP

nefazodone results in increased expression of TCEA1 mRNA

NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156
Ensembl chr 5:12,831,339...12,834,156

G

t-complex 1

increases expression

EXP

nefazodone results in increased expression of TCP1 mRNA

NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527

G

thymine-DNA glycosylase

increases expression

EXP

nefazodone results in increased expression of TDG mRNA

NCBI chr 7:22,965,388...22,990,311
Ensembl chr 7:22,965,388...22,985,100

G

TEF transcription factor, PAR bZIP family member

increases expression

EXP

nefazodone results in increased expression of TEF mRNA

NCBI chr 7:115,197,180...115,221,930
Ensembl chr 7:115,193,282...115,221,928

G

transcription elongation factor, mitochondrial

increases expression

EXP

nefazodone results in increased expression of TEFM mRNA

NCBI chr10:65,617,547...65,622,042
Ensembl chr10:65,617,550...65,622,042

G

terminal nucleotidyltransferase 2

decreases expression

EXP

nefazodone results in decreased expression of TENT2 mRNA

NCBI chr 2:26,115,150...26,167,465
Ensembl chr 2:26,115,240...26,167,113

G

terminal nucleotidyltransferase 4B

increases expression

EXP

nefazodone results in increased expression of TENT4B mRNA

NCBI chr19:34,984,244...35,042,423
Ensembl chr19:34,980,296...35,042,399

G

terminal nucleotidyltransferase 5A

decreases expression

EXP

nefazodone results in decreased expression of TENT5A mRNA

NCBI chr 8:95,102,349...95,109,100
Ensembl chr 8:95,105,412...95,109,100

G

testis expressed 261

increases expression

EXP

nefazodone results in increased expression of TEX261 mRNA

NCBI chr 4:117,813,050...117,818,408
Ensembl chr 4:117,811,176...117,819,180

G

testis expressed 264

increases expression

EXP

nefazodone results in increased expression of TEX264 mRNA

NCBI chr 8:107,295,806...107,322,858
Ensembl chr 8:116,174,518...116,201,667

G

transferrin

decreases expression

EXP

nefazodone results in decreased expression of TF mRNA

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transcription factor A, mitochondrial

increases expression

EXP

nefazodone results in increased expression of TFAM mRNA

NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877

G

transcription factor B2, mitochondrial

increases expression

EXP

nefazodone results in increased expression of TFB2M mRNA

NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594

G

transcription factor binding to IGHM enhancer 3

increases expression

EXP

nefazodone results in increased expression of TFE3 mRNA

NCBI chr X:17,401,466...17,414,829
Ensembl chr X:17,401,466...17,414,685

G

tissue factor pathway inhibitor

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TFPI mRNA

NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742

G

transferrin receptor

increases expression

EXP

nefazodone results in increased expression of TFRC mRNA

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor, beta induced

decreases expression

EXP

nefazodone results in decreased expression of TGFBI mRNA

NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471

G

transglutaminase 2

decreases expression

EXP

nefazodone results in decreased expression of TGM2 mRNA

NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240

G

threonine synthase-like 2

decreases expression

EXP

nefazodone results in decreased expression of THNSL2 mRNA

NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959

G

thyroid hormone responsive

decreases expression

EXP

nefazodone results in decreased expression of THRSP mRNA

NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827

G

THUMP domain containing 3

increases expression

EXP

nefazodone results in increased expression of THUMPD3 mRNA

NCBI chr 4:147,741,288...147,764,254
Ensembl chr 4:147,741,309...147,765,579

G

translocase of inner mitochondrial membrane 10

increases expression

EXP

nefazodone results in increased expression of TIMM10 mRNA

NCBI chr 3:90,315,048...90,318,613
Ensembl chr 3:90,315,092...90,318,614

G

translocase of inner mitochondrial membrane 10B

increases expression

EXP

nefazodone results in increased expression of TIMM10B mRNA

NCBI chr 1:169,392,355...169,395,201
Ensembl chr 1:169,392,177...169,395,205

G

translocase of inner mitochondrial membrane 13

increases expression

EXP

nefazodone results in increased expression of TIMM13 mRNA

NCBI chr 7:9,459,490...9,460,849
Ensembl chr 7:9,459,582...9,460,862

G

translocase of inner mitochondrial membrane 17A

increases expression

EXP

nefazodone results in increased expression of TIMM17A mRNA

NCBI chr13:49,282,918...49,296,363
Ensembl chr13:49,282,918...49,307,904

G

translocase of inner mitochondrial membrane 29

increases expression

EXP

nefazodone results in increased expression of TIMM29 mRNA

NCBI chr 8:28,421,370...28,424,339
Ensembl chr 8:28,421,370...28,424,339

G

translocase of inner mitochondrial membrane 8A1

increases expression

EXP

nefazodone results in increased expression of TIMM8A1 mRNA

NCBI chr X:102,011,206...102,015,444
Ensembl chr X:102,011,206...102,015,444

G

translocase of inner mitochondrial membrane 8 homolog B

increases expression

EXP

nefazodone results in increased expression of TIMM8B mRNA

NCBI chr 8:59,850,737...59,852,117
Ensembl chr 8:59,850,728...59,852,962

G

translocase of inner mitochondrial membrane 9

increases expression

EXP

nefazodone results in increased expression of TIMM9 mRNA

NCBI chr 6:95,346,065...95,358,895
Ensembl chr 6:95,346,065...95,358,895

G

tight junction protein 2

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of TJP2 mRNA

NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:231,136,243...231,264,750

G

transketolase

increases expression

EXP

nefazodone results in increased expression of TKT mRNA

NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431

G

TLE family member 5, transcriptional modulator

decreases expression

EXP

nefazodone results in decreased expression of TLE5 mRNA

NCBI chr 7:8,794,123...8,801,056
Ensembl chr 7:8,793,796...8,801,054

G

toll-like receptor 4

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TLR4 mRNA

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007

G

TM2 domain containing 1

increases expression

EXP

nefazodone results in increased expression of TM2D1 mRNA

NCBI chr 5:118,136,299...118,177,639
Ensembl chr 5:118,136,299...118,170,283

G

TM2 domain containing 3

increases expression

EXP

nefazodone results in increased expression of TM2D3 mRNA

NCBI chr 1:119,267,194...119,277,094
Ensembl chr 1:128,677,629...128,687,580

G

transmembrane 9 superfamily member 3

increases expression

EXP

nefazodone results in increased expression of TM9SF3 mRNA

NCBI chr 1:249,981,458...250,034,247
Ensembl chr 1:249,981,458...250,034,247

G

transmembrane and coiled-coil domain family 2

decreases expression

EXP

nefazodone results in decreased expression of TMCC2 mRNA

NCBI chr13:43,794,029...43,831,716
Ensembl chr13:46,346,177...46,383,862

G

transmembrane and coiled-coil domains 1

increases expression

EXP

nefazodone results in increased expression of TMCO1 mRNA

NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201

G

transmembrane p24 trafficking protein 2

increases expression

EXP

nefazodone results in increased expression of TMED2 mRNA

NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606

G

transmembrane p24 trafficking protein 9

increases expression

EXP

nefazodone results in increased expression of TMED9 mRNA

NCBI chr17:9,034,797...9,039,311
Ensembl chr17:9,034,823...9,039,319

G

transmembrane protein 106B

increases expression

EXP

nefazodone results in increased expression of TMEM106B mRNA

NCBI chr 4:42,294,074...42,313,426
Ensembl chr 4:42,294,101...42,313,407

G

transmembrane protein 11

increases expression

EXP

nefazodone results in increased expression of TMEM11 mRNA

NCBI chr10:45,542,753...45,557,570
Ensembl chr 6:125,690,543...125,691,404
Ensembl chr10:125,690,543...125,691,404

G

transmembrane protein 126A

increases expression

EXP

nefazodone results in increased expression of TMEM126A mRNA

NCBI chr 1:153,837,015...153,843,192
Ensembl chr 1:153,835,236...153,843,160

G

transmembrane protein 134

increases expression

EXP

nefazodone results in increased expression of TMEM134 mRNA

NCBI chr 1:210,848,761...210,857,735
Ensembl chr 1:210,848,578...210,858,861

G

transmembrane protein 140

decreases expression

EXP

nefazodone results in decreased expression of TMEM140 mRNA

NCBI chr 4:64,503,621...64,514,620
Ensembl chr 4:64,500,439...64,521,990

G

transmembrane protein 147

increases expression

EXP

nefazodone results in increased expression of TMEM147 mRNA

NCBI chr 1:95,104,448...95,106,268
Ensembl chr 1:95,104,452...95,106,283

G

transmembrane protein 14C

increases expression

EXP

nefazodone results in increased expression of TMEM14C mRNA

NCBI chr17:23,939,501...23,945,622
Ensembl chr17:23,939,509...23,959,055

G

transmembrane protein 176A

decreases expression

EXP

nefazodone results in decreased expression of TMEM176A mRNA

NCBI chr 4:79,101,946...79,109,499
Ensembl chr 4:79,101,857...79,111,175

G

transmembrane protein 205

increases expression

EXP

nefazodone results in increased expression of TMEM205 mRNA

NCBI chr 8:28,728,172...28,733,908
Ensembl chr 8:28,728,172...28,733,908

G

transmembrane protein 208

increases expression

EXP

nefazodone results in increased expression of TMEM208 mRNA

NCBI chr19:33,203,587...33,206,287
Ensembl chr19:50,113,510...50,124,153

G

transmembrane protein 259

increases expression

EXP

nefazodone results in increased expression of TMEM259 mRNA

NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:10,373,119...10,381,566

G

transmembrane protein 33

increases expression

EXP

nefazodone results in increased expression of TMEM33 mRNA

NCBI chr14:41,242,358...41,264,586
Ensembl chr14:41,242,358...41,264,586

G

transmembrane protein 38B

increases expression

EXP

nefazodone results in increased expression of TMEM38B mRNA

NCBI chr 5:73,255,662...73,291,383
Ensembl chr 5:73,255,632...73,292,384

G

transmembrane protein 41a

increases expression

EXP

nefazodone results in increased expression of TMEM41A mRNA

NCBI chr11:79,084,005...79,090,613
Ensembl chr11:92,588,489...92,595,715

G

transmembrane protein 60

increases expression

EXP

nefazodone results in increased expression of TMEM60 mRNA

NCBI chr 4:15,102,168...15,107,023
Ensembl chr 4:15,100,348...15,107,139

G

transmembrane protein 62

increases expression

EXP

nefazodone results in increased expression of TMEM62 mRNA

NCBI chr 3:128,380,366...128,415,583
Ensembl chr 3:128,375,500...128,415,583

G

transmembrane protein 69

increases expression

EXP

nefazodone results in increased expression of TMEM69 mRNA

NCBI chr 5:135,241,557...135,247,323
Ensembl chr 5:135,241,560...135,247,215

G

TMEM9 domain family, member B

increases expression

EXP

nefazodone results in increased expression of TMEM9B mRNA

NCBI chr 1:163,755,307...163,783,880
Ensembl chr 1:173,200,869...173,218,053

G

thymosin beta 4, X-linked

decreases expression

EXP

nefazodone results in decreased expression of TMSB4X mRNA

NCBI chr X:30,761,611...30,763,612
Ensembl chr X:30,761,612...30,763,613

G

thioredoxin-related transmembrane protein 1

increases expression

EXP

nefazodone results in increased expression of TMX1 mRNA

NCBI chr 6:94,696,699...94,707,751
Ensembl chr 6:94,696,358...94,708,618

G

thioredoxin-related transmembrane protein 2

increases expression

EXP

nefazodone results in increased expression of TMX2 mRNA

NCBI chr 3:90,161,628...90,169,278
Ensembl chr 3:90,160,930...90,169,278

G

tumor necrosis factor

multiple interactions

ISO
EXP

[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 10b

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TNFRSF10A mRNA

NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082

G

TNF receptor superfamily member 1A

increases expression

EXP

nefazodone results in increased expression of TNFRSF1A mRNA

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF superfamily member 10

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of TNFSF10 mRNA

NCBI chr 2:112,136,550...112,155,903

G

TNF superfamily member 11

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TNFSF11 mRNA

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479

G

translocase of outer mitochondrial membrane 20

increases expression

EXP

nefazodone results in increased expression of TOMM20 mRNA

NCBI chr19:71,822,429...71,832,420
Ensembl chr19:71,822,411...71,832,510

G

translocase of outer mitochondrial membrane 5

increases expression

EXP

nefazodone results in increased expression of TOMM5 mRNA

NCBI chr 5:64,158,026...64,160,857

G

translocase of outer mitochondrial membrane 70

increases expression

EXP

nefazodone results in increased expression of TOMM70A mRNA

NCBI chr11:56,847,837...56,886,302
Ensembl chr11:56,846,334...56,886,320

G

torsin family 1, member A

increases expression

EXP

nefazodone results in increased expression of TOR1A mRNA

NCBI chr 3:34,648,421...34,655,453
Ensembl chr 3:34,648,422...34,655,417

G

tumor protein p53 inducible protein 3

decreases expression

EXP

nefazodone results in decreased expression of TP53I3 mRNA

NCBI chr 6:33,537,779...33,545,204

G

tumor protein p53 inducible nuclear protein 2

decreases expression

EXP

nefazodone results in decreased expression of TP53INP2 mRNA

NCBI chr 3:164,341,618...164,350,270
Ensembl chr 3:164,343,205...164,350,225

G

two pore segment channel 1

decreases expression

EXP

nefazodone results in decreased expression of TPCN1 mRNA

NCBI chr12:41,633,399...41,690,200
Ensembl chr12:41,633,398...41,690,200

G

tropomyosin 1

increases expression

EXP

nefazodone results in increased expression of TPM1 mRNA

NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468

G

tropomyosin 3

increases expression

EXP

nefazodone results in increased expression of TPM3 mRNA

NCBI chr 2:177,812,534...177,842,661
Ensembl chr 2:177,814,883...177,842,660

G

tropomyosin 4

decreases expression

EXP

nefazodone results in decreased expression of TPM4 mRNA

NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494

G

tumor protein p63 regulated 1-like

increases expression

EXP

nefazodone results in increased expression of TPRG1L mRNA

NCBI chr 5:170,004,577...170,007,784
Ensembl chr 5:170,004,577...170,007,983

G

tyrosylprotein sulfotransferase 1

decreases expression

EXP

nefazodone results in decreased expression of TPST1 mRNA

NCBI chr12:32,180,688...32,247,478
Ensembl chr12:32,180,936...32,241,821

G

TraB domain containing

increases expression

EXP

nefazodone results in increased expression of TRABD mRNA

NCBI chr 7:122,034,685...122,045,657
Ensembl chr 7:122,038,553...122,045,657

G

trafficking kinesin protein 1

decreases expression

EXP

nefazodone results in decreased expression of TRAK1 mRNA

NCBI chr 8:129,861,967...130,016,870
Ensembl chr 8:129,861,977...130,016,870

G

trafficking protein particle complex subunit 13

increases expression

EXP

nefazodone results in increased expression of TRAPPC13 mRNA

NCBI chr 2:37,004,288...37,035,837
Ensembl chr 2:37,002,976...37,035,820

G

tribbles pseudokinase 3

increases expression

EXP

nefazodone results in increased expression of TRIB3 mRNA

NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802

G

tripartite motif-containing 26

decreases expression

EXP

nefazodone results in decreased expression of TRIM26 mRNA

NCBI chr20:1,711,564...1,736,389
Ensembl chr20:1,715,005...1,736,623

G

tripartite motif-containing 5

decreases expression

EXP

nefazodone results in decreased expression of TRIM5 mRNA

NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:168,132,308...168,141,657

G

tRNA methyltransferase 1

increases expression

EXP

nefazodone results in increased expression of TRMT1 mRNA

NCBI chr19:40,361,583...40,374,971
Ensembl chr19:40,361,583...40,374,622

G

Ts translation elongation factor, mitochondrial

increases expression

EXP

nefazodone results in increased expression of TSFM mRNA

NCBI chr 7:64,714,330...64,750,106
Ensembl chr 7:64,714,036...64,750,171

G

tsukushi, small leucine rich proteoglycan

increases expression

EXP

nefazodone results in increased expression of TSKU mRNA

NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272

G

translin-associated factor X

increases expression

EXP

nefazodone results in increased expression of TSNAX mRNA

NCBI chr19:69,873,210...69,887,244
Ensembl chr19:69,872,987...69,887,224

G

tetratricopeptide repeat domain 1

increases expression

EXP

nefazodone results in increased expression of TTC1 mRNA

NCBI chr10:28,703,763...28,728,910
Ensembl chr10:28,703,769...28,728,882

G

tetratricopeptide repeat domain 13

decreases expression

EXP

nefazodone results in decreased expression of TTC13 mRNA

NCBI chr19:69,534,989...69,589,590
Ensembl chr19:69,534,989...69,589,563

G

tetratricopeptide repeat domain 3

decreases expression

EXP

nefazodone results in decreased expression of TTC3 mRNA

NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418

G

tweety family member 2

decreases expression

EXP

nefazodone results in decreased expression of TTYH2 mRNA

NCBI chr10:100,208,129...100,252,505
Ensembl chr10:100,207,860...100,253,521

G

tweety family member 3

decreases expression

EXP

nefazodone results in decreased expression of TTYH3 mRNA

NCBI chr12:19,110,973...19,139,379
Ensembl chr12:19,110,824...19,139,371

G

tubulin, alpha 1C

increases expression

EXP

nefazodone results in increased expression of TUBA1C mRNA

NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311

G

tubulin, beta 2A class IIa

decreases expression

EXP

nefazodone results in decreased expression of TUBB2A mRNA

NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,983,387...31,006,838

G

terminal uridylyl transferase 7

decreases expression

EXP

nefazodone results in decreased expression of TUT7 mRNA

NCBI chr17:4,854,553...4,908,758
Ensembl chr17:4,855,936...4,909,070

G

thioredoxin 1

increases expression

EXP

nefazodone results in increased expression of TXN1 mRNA

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307

G

thioredoxin-like 1

increases expression

EXP

nefazodone results in increased expression of TXNL1 mRNA

NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518

G

thioredoxin reductase 1

increases expression

EXP

nefazodone results in increased expression of TXNRD1 mRNA

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817

G

trypsin like peroxisomal matrix peptidase 1

increases expression

EXP

nefazodone results in increased expression of TYSND1 mRNA

NCBI chr20:30,180,878...30,188,239
Ensembl chr20:30,181,090...30,188,236

G

U2 small nuclear RNA auxiliary factor 1

increases expression

EXP

nefazodone results in increased expression of U2AF1 mRNA

NCBI chr20:9,744,206...9,755,146
Ensembl chr20:9,744,207...9,755,094

G

ubiquitin-like modifier activating enzyme 3

increases expression

EXP

nefazodone results in increased expression of UBA3 mRNA

NCBI chr 4:131,346,219...131,367,378
Ensembl chr 4:131,346,224...131,367,277

G

ubiquitin-like modifier activating enzyme 5

multiple interactions

ISO

[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of UBA5 mRNA

NCBI chr 8:113,544,037...113,559,711
Ensembl chr 8:113,544,037...113,559,711

G

ubiquitin-conjugating enzyme E2D 3

increases expression

EXP

nefazodone results in increased expression of UBE2D3 mRNA

NCBI chr 2:226,543,194...226,571,001
Ensembl chr 2:226,540,531...226,573,144

G

ubiquitin-conjugating enzyme E2F (putative)

increases expression

EXP

nefazodone results in increased expression of UBE2F mRNA

NCBI chr 9:99,293,506...99,328,690
Ensembl chr 9:99,293,515...99,330,479

G

ubiquitin-conjugating enzyme E2K

increases expression

EXP

nefazodone results in increased expression of UBE2K mRNA

NCBI chr14:43,011,681...43,077,825
Ensembl chr14:43,011,681...43,072,462

G

ubiquitin-conjugating enzyme E2L 3

increases expression

EXP

nefazodone results in increased expression of UBE2L3 mRNA

NCBI chr11:97,300,584...97,343,084
Ensembl chr11:97,301,945...97,343,084

G

ubiquitin-conjugating enzyme E2M

increases expression

EXP

nefazodone results in increased expression of UBE2M mRNA

NCBI chr 1:73,662,576...73,666,113

G

ubiquitin-conjugating enzyme E2N

increases expression

EXP

nefazodone results in increased expression of UBE2N mRNA

NCBI chr 7:32,041,190...32,071,252

G

ubiquitin conjugating enzyme E2 Q2

increases expression

EXP

nefazodone results in increased expression of UBE2Q2 mRNA

NCBI chr 8:64,414,502...64,474,425
Ensembl chr 8:64,414,301...64,474,418

G

ubiquitin conjugating enzyme E2 V2

increases expression

EXP

nefazodone results in increased expression of UBE2V2 mRNA

NCBI chr11:98,808,681...98,842,583
Ensembl chr11:98,807,538...98,843,211

G

ubiquitin-conjugating enzyme E2Z

increases expression

EXP

nefazodone results in increased expression of UBE2Z mRNA

NCBI chr10:80,997,816...81,016,936
Ensembl chr10:81,494,523...81,513,641

G

ubiquitin protein ligase E3A

increases expression

EXP

nefazodone results in increased expression of UBE3A mRNA

NCBI chr 1:119,204,244...119,297,097
Ensembl chr 1:119,206,148...119,297,097

G

ubiquitin protein ligase E3C

increases expression

EXP

nefazodone results in increased expression of UBE3C mRNA

NCBI chr 4:6,323,831...6,425,085
Ensembl chr 4:6,323,831...6,424,845

G

ubiquitination factor E4A

increases expression

EXP

nefazodone results in increased expression of UBE4A mRNA

NCBI chr 8:54,132,799...54,174,921
Ensembl chr 8:54,132,801...54,174,835

G

ubiquitination factor E4B

increases expression

EXP

nefazodone results in increased expression of UBE4B mRNA

NCBI chr 5:165,049,897...165,153,572
Ensembl chr 5:165,049,897...165,153,572

G

ubiquitin family domain containing 1

increases expression

EXP

nefazodone results in increased expression of UBFD1 mRNA

NCBI chr 1:176,626,003...176,640,993
Ensembl chr 1:186,057,123...186,066,103

G

ubiquitin-like 3

increases expression

EXP

nefazodone results in increased expression of UBL3 mRNA

NCBI chr12:6,473,684...6,518,331
Ensembl chr12:11,509,848...11,554,547

G

ubiquilin 1

increases expression

EXP

nefazodone results in increased expression of UBQLN1 mRNA

NCBI chr17:6,438,456...6,482,498
Ensembl chr17:6,444,124...6,482,499

G

ubiquilin 2

increases expression

EXP

nefazodone results in increased expression of UBQLN2 mRNA

NCBI chr X:21,228,809...21,232,228
Ensembl chr X:21,229,197...21,232,268

G

ubiquitin protein ligase E3 component n-recognin 4

increases expression

EXP

nefazodone results in increased expression of UBR4 mRNA

NCBI chr 5:156,919,029...157,027,127
Ensembl chr 5:156,919,085...157,027,127

G

UBX domain protein 1

increases expression

EXP

nefazodone results in increased expression of UBXN1 mRNA

NCBI chr 1:215,194,418...215,198,343
Ensembl chr 1:215,174,216...215,198,343

G

UBX domain protein 4

increases expression

EXP

nefazodone results in increased expression of UBXN4 mRNA

NCBI chr13:39,740,064...39,772,493
Ensembl chr13:42,292,528...42,326,143

G

ubiquitin C-terminal hydrolase L3, pseudogene 1

increases expression

EXP

nefazodone results in increased expression of UCHL3-PS1 mRNA

NCBI chr 3:161,856,954...161,857,835

G

ubiquitin C-terminal hydrolase L5

increases expression

EXP

nefazodone results in increased expression of UCHL5 mRNA

NCBI chr13:58,070,947...58,106,825
Ensembl chr13:58,042,029...58,107,441

G

ubiquitin recognition factor in ER associated degradation 1

increases expression

EXP

nefazodone results in increased expression of UFD1 mRNA

NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434

G

Ufm1-specific ligase 1

increases expression

EXP

nefazodone results in increased expression of UFL1 mRNA

NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:43,758,098...43,791,682

G

UDP-glucose 6-dehydrogenase

increases expression

EXP

nefazodone results in increased expression of UGDH mRNA

NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629

G

UDP-glucose glycoprotein glucosyltransferase 1

increases expression

EXP

nefazodone results in increased expression of UGGT1 mRNA

NCBI chr 9:45,851,127...45,964,454
Ensembl chr 9:45,854,985...45,964,455

G

UDP glucuronosyltransferase family 1 member A6

increases expression

EXP

nefazodone results in increased expression of UGT1A6 mRNA

NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase 2 family, polypeptide B1

increases expression

EXP

nefazodone results in increased expression of UGT2B17 mRNA

NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331

G

unc-51 like autophagy activating kinase 2

decreases expression

EXP

nefazodone results in decreased expression of ULK2 mRNA

NCBI chr10:46,951,038...47,029,844
Ensembl chr10:46,951,038...47,029,844

G

uridine monophosphate synthetase

increases expression

EXP

nefazodone results in increased expression of UMPS mRNA

NCBI chr11:80,311,269...80,321,678
Ensembl chr11:80,311,214...80,327,828

G

uracil-DNA glycosylase

increases expression

EXP

nefazodone results in increased expression of UNG mRNA

NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257

G

unk like zinc finger

increases expression

EXP

nefazodone results in increased expression of UNKL mRNA

NCBI chr10:14,710,627...14,756,725
Ensembl chr10:14,710,563...14,756,724

G

ubiquinol-cytochrome c reductase core protein 1

increases expression

EXP

nefazodone results in increased expression of UQCRC1 mRNA

NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:118,468,200...118,479,964

G

ubiquinol cytochrome c reductase core protein 2

increases expression

EXP

nefazodone results in increased expression of UQCRC2 mRNA

NCBI chr 1:184,599,240...184,629,804
Ensembl chr 1:184,599,212...184,630,946

G

URI1, prefoldin-like chaperone

increases expression

EXP

nefazodone results in increased expression of URI1 mRNA

NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:99,783,158...99,853,906

G

unconventional SNARE in the ER 1

increases expression

EXP

nefazodone results in increased expression of USE1 mRNA

NCBI chr16:18,038,284...18,041,826
Ensembl chr16:18,070,793...18,075,814

G

ubiquitin specific peptidase 10

increases expression

EXP

nefazodone results in increased expression of USP10 mRNA

NCBI chr19:64,881,255...64,923,522
Ensembl chr19:64,881,315...64,923,519

G

ubiquitin specific peptidase 14

increases expression

EXP

nefazodone results in increased expression of USP14 mRNA

NCBI chr18:1,292,745...1,330,867
Ensembl chr18:1,292,745...1,330,336

G

ubiquitin specific peptidase 3

increases expression

EXP

nefazodone results in increased expression of USP3 mRNA

NCBI chr 8:75,973,278...76,049,151
Ensembl chr 8:75,974,615...76,049,153

G

ubiquitin specific peptidase 39

increases expression

EXP

nefazodone results in increased expression of USP39 mRNA

NCBI chr 4:105,932,140...105,964,551
Ensembl chr 4:105,932,140...105,964,551

G

ubiquitin specific peptidase 47

increases expression

EXP

nefazodone results in increased expression of USP47 mRNA

NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:175,586,723...175,669,904

G

ubiquitin specific peptidase 5

increases expression

EXP

nefazodone results in increased expression of USP5 mRNA

NCBI chr 4:159,305,927...159,321,345
Ensembl chr 4:159,305,938...159,320,956

G

ubiquitin specific peptidase 7

increases expression

EXP

nefazodone results in increased expression of USP7 mRNA

NCBI chr10:7,335,508...7,432,018
Ensembl chr10:7,367,604...7,432,013

G

integral membrane transport protein UST4r

increases expression

EXP

nefazodone results in increased expression of UST4R mRNA

NCBI chr 1:205,072,204...205,142,718
Ensembl chr 1:214,501,347...214,571,832

G

integral membrane transport protein UST5r

decreases expression

EXP

nefazodone results in decreased expression of UST5R mRNA

NCBI chr 1:214,640,172...214,716,024
Ensembl chr 1:214,640,172...214,715,861

G

vesicle amine transport 1

increases expression

EXP

nefazodone results in increased expression of VAT1 mRNA

NCBI chr10:86,889,793...86,897,411
Ensembl chr10:86,889,793...86,897,411

G

valosin-containing protein

increases expression

EXP

nefazodone results in increased expression of VCP mRNA

NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387

G

voltage-dependent anion channel 1

increases expression

EXP

nefazodone results in increased expression of VDAC1 mRNA

NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541

G

voltage-dependent anion channel 3

increases expression

EXP

nefazodone results in increased expression of VDAC3 mRNA

NCBI chr16:76,137,489...76,153,933
Ensembl chr16:76,137,504...76,155,304

G

vimentin

decreases expression

EXP

nefazodone results in decreased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746

G

vitamin K epoxide reductase complex, subunit 1

decreases expression

EXP

nefazodone results in decreased expression of VKORC1 mRNA

NCBI chr 1:191,932,969...191,935,490

G

vitamin K epoxide reductase complex, subunit 1-like 1

increases expression

EXP

nefazodone results in increased expression of VKORC1L1 mRNA

NCBI chr12:32,354,078...32,404,327

G

vanin 1

increases expression

EXP

nefazodone results in increased expression of VNN1 mRNA

NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629

G

VPS26 retromer complex component A

increases expression

EXP

nefazodone results in increased expression of VPS26A mRNA

NCBI chr20:30,947,018...30,976,964
Ensembl chr20:30,947,023...30,976,827

G

VPS29 retromer complex component

increases expression

EXP

nefazodone results in increased expression of VPS29 mRNA

NCBI chr12:39,869,688...39,878,732
Ensembl chr12:39,869,688...39,878,848

G

VPS35 retromer complex component

increases expression

EXP

nefazodone results in increased expression of VPS35 mRNA

NCBI chr19:37,938,989...37,974,887
Ensembl chr19:37,938,720...37,974,886

G

von Willebrand factor A domain containing 8

increases expression

EXP

nefazodone results in increased expression of VWA8 mRNA

NCBI chr15:60,661,764...60,985,971
Ensembl chr15:60,661,877...60,985,971

G

WAPL cohesin release factor

increases expression

EXP

nefazodone results in increased expression of WAPL mRNA

NCBI chr16:10,011,741...10,081,472
Ensembl chr16:10,012,110...10,081,472

G

WASP like actin nucleation promoting factor

increases expression

EXP

nefazodone results in increased expression of WASL mRNA

NCBI chr 4:54,049,081...54,097,653
Ensembl chr 4:54,049,082...54,097,570

G

WD repeat domain 36

increases expression

EXP

nefazodone results in increased expression of WDR36 mRNA

NCBI chr18:24,747,812...24,783,704
Ensembl chr18:24,747,832...24,783,110

G

WD repeat domain 45

increases expression

EXP

nefazodone results in increased expression of WDR45 mRNA

NCBI chr X:17,448,195...17,454,117
Ensembl chr X:17,448,207...17,454,117

G

WD repeat domain 77

increases expression

EXP

nefazodone results in increased expression of WDR77 mRNA

NCBI chr 2:196,123,882...196,133,853
Ensembl chr 2:196,123,848...196,134,567

G

WD repeat and SOCS box-containing 1

decreases expression

EXP

nefazodone results in decreased expression of WSB1 mRNA

NCBI chr10:64,700,752...64,717,038
Ensembl chr10:64,700,762...64,716,832

G

WWC family member 3

increases expression

EXP

nefazodone results in increased expression of WWC3 mRNA

NCBI chr X:27,146,018...27,263,446
Ensembl chr X:27,145,812...27,263,446

G

X-box binding protein 1

increases splicing

ISO

nefazodone results in increased splicing of XBP1 mRNA

NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706

G

xanthine dehydrogenase

decreases expression

EXP

nefazodone results in decreased expression of XDH mRNA

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350

G

XPC complex subunit, DNA damage recognition and repair factor

decreases expression

EXP

nefazodone results in decreased expression of XPC mRNA

NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305

G

X-prolyl aminopeptidase 2

decreases expression

EXP

nefazodone results in decreased expression of XPNPEP2 mRNA

NCBI chr X:132,165,696...132,194,937
Ensembl chr X:132,165,701...132,195,126

G

exportin 1

increases expression

EXP

nefazodone results in increased expression of XPO1 mRNA

NCBI chr14:101,434,450...101,476,705
Ensembl chr14:101,434,517...101,476,714

G

exportin for tRNA

increases expression

EXP

nefazodone results in increased expression of XPOT mRNA

NCBI chr 7:58,997,025...59,037,506
Ensembl chr 7:58,997,025...59,037,502

G

tyrosyl-tRNA synthetase 1

increases expression

EXP

nefazodone results in increased expression of YARS1 mRNA

NCBI chr 5:146,820,163...146,848,377
Ensembl chr 5:146,819,358...146,848,377

G

Yip1 interacting factor homolog A, membrane trafficking protein

increases expression

EXP

nefazodone results in increased expression of YIF1A mRNA

NCBI chr 1:202,394,923...202,399,125
Ensembl chr 1:211,824,273...211,828,802

G

Yip1 domain family, member 1

decreases expression

EXP

nefazodone results in decreased expression of YIPF1 mRNA

NCBI chr 5:122,112,144...122,147,729
Ensembl chr 5:127,340,953...127,376,538

G

Yip1 domain family, member 4

increases expression

EXP

nefazodone results in increased expression of YIPF4 mRNA

NCBI chr 6:26,702,647...26,714,066
Ensembl chr 6:26,682,488...26,714,066

G

yippee-like 3

decreases expression

EXP

nefazodone results in decreased expression of YPEL3 mRNA

NCBI chr 1:190,814,920...190,818,248
Ensembl chr 1:190,814,512...190,818,251

G

yippee-like 5

increases expression

EXP

nefazodone results in increased expression of YPEL5 mRNA

NCBI chr 6:28,408,079...28,423,536
Ensembl chr 6:28,408,080...28,412,385

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

increases expression

EXP

nefazodone results in increased expression of YWHAB mRNA

NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

increases expression

EXP

nefazodone results in increased expression of YWHAG mRNA

NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

increases expression

EXP

nefazodone results in increased expression of YWHAQ mRNA

NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

increases expression

EXP

nefazodone results in increased expression of YWHAZ mRNA

NCBI chr 7:69,826,404...69,848,702
Ensembl chr 7:69,826,404...69,849,007

G

zinc finger and BTB domain containing 20

decreases expression

EXP

nefazodone results in decreased expression of ZBTB20 mRNA

NCBI chr11:70,558,010...71,297,039
Ensembl chr11:70,580,930...70,736,237

G

zinc finger DHHC-type palmitoyltransferase 7

increases expression

EXP

nefazodone results in increased expression of ZDHHC7 mRNA

NCBI chr19:65,048,140...65,065,286
Ensembl chr19:65,037,310...65,065,286

G

zinc finger AN1-type containing 2A

increases expression

EXP

nefazodone results in increased expression of ZFAND2A mRNA

NCBI chr12:20,275,435...20,286,513
Ensembl chr12:20,275,450...20,286,513

G

zinc finger protein 110

decreases expression

EXP

nefazodone results in decreased expression of ZFP110 mRNA

NCBI chr 1:82,509,563...82,533,294
Ensembl chr 1:82,517,769...82,533,292

G

zinc finger protein 260

decreases expression

EXP

nefazodone results in decreased expression of ZFP260 mRNA

NCBI chr 1:94,469,861...94,477,377
Ensembl chr 1:94,460,733...94,478,217

G

zinc finger protein 36, C3H type-like 1

decreases expression

EXP

nefazodone results in decreased expression of ZFP36L1 mRNA

NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979

G

zinc finger protein 386 (Kruppel-like)

decreases expression

EXP

nefazodone results in decreased expression of ZFP386 mRNA

NCBI chr 6:143,109,563...143,124,266
Ensembl chr 6:143,109,610...143,127,027

G

zinc finger protein 598

increases expression

EXP

nefazodone results in increased expression of ZFP598 mRNA

NCBI chr10:14,198,763...14,210,773
Ensembl chr10:14,185,611...14,210,772

G

zinc finger protein 706

increases expression

EXP

nefazodone results in increased expression of ZFP706 mRNA

NCBI chr 7:70,050,960...70,059,588
Ensembl chr 7:70,052,534...70,059,159

G

zinc finger FYVE-type containing 21

decreases expression

EXP

nefazodone results in decreased expression of ZFYVE21 mRNA

NCBI chr 6:136,695,132...136,715,601
Ensembl chr 6:136,694,908...136,715,601

G

zinc finger with KRAB and SCAN domains 3

decreases expression

EXP

nefazodone results in decreased expression of ZKSCAN3 mRNA

NCBI chr17:47,912,816...47,928,553
Ensembl chr17:47,912,912...47,928,551

G

zinc finger, MIZ-type containing 2

decreases expression

EXP

nefazodone results in decreased expression of ZMIZ2 mRNA

NCBI chr14:85,465,323...85,481,860
Ensembl chr14:85,465,373...85,481,860

G

ZPR1 zinc finger

increases expression

EXP

nefazodone results in increased expression of ZPR1 mRNA

NCBI chr 8:55,461,839...55,471,413
Ensembl chr 8:55,461,839...55,471,413

G

ZW10 interacting kinetochore protein

increases expression

EXP

nefazodone results in increased expression of ZWINT mRNA

NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	20862
role	20820
biological role	20818
pharmacological role	19911
analgesic	14901
nefazodone	1773
nefazodone hydrochloride	0
Path 2
Term	Annotations
CHEBI ontology	20862
subatomic particle	20860
composite particle	20860
hadron	20860
baryon	20860
nucleon	20860
atomic nucleus	20860
atom	20860
main group element atom	20781
main group molecular entity	20781
s-block molecular entity	20574
hydrogen molecular entity	20558
hydrides	19693
inorganic hydride	18602
pnictogen hydride	18589
nitrogen hydride	18502
azane	18262
ammonia	18261
organic amino compound	18261
tertiary amino compound	11023
N-alkylpiperazine	3447
nefazodone	1773
nefazodone hydrochloride	0

paths to the root