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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.4.23.46 (memapsin 2) inhibitor
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Accession:CHEBI:74925 term browser browse the term
Definition:An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of memapsin 2 (EC 3.4.23.46).
Synonyms:related_synonym: BACE1 inhibitor;   BACE1 inhibitors;   EC 3.4.23.46 (memapsin 2) inhibitors;   EC 3.4.23.46 inhibitor;   EC 3.4.23.46 inhibitors;   Gamma-secretase inhibitor;   beta-secretase inhibitor;   beta-secretase inhibitors;   beta-site APP-cleaving enzyme 1 inhibitor;   beta-site APP-cleaving enzyme 1 inhibitors;   beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor;   beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors;   beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitor;   beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitors;   gamma-secretase inhibitors;   memapsin 2 inhibitor;   memapsin 2 inhibitors;   membrane-associated aspartic protease 2 inhibitor;   membrane-associated aspartic protease 2 inhibitors
 xref: Wikipedia:Gamma_secretase


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Path 1
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      biological role 0
        biochemical role 0
          enzyme inhibitor 0
            EC 3.* (hydrolase) inhibitor 0
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 0
                EC 3.4.23.* (aspartic endopeptidase) inhibitor 0
                  EC 3.4.23.46 (memapsin 2) inhibitor 0
                    C-2'-decoumaroyl-aloeresin G 0
                    DAPT 0
                    GCB 0
                    L-685,458 + 0
                    LY-411575 0
                    RO4929097 0
                    Z-Val-Phe-H 0
                    compound E 0
                    loganin + 0
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