Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:fluticasone furoate
go back to main search page
Accession:CHEBI:74899 term browser browse the term
Definition:A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease.
Synonyms:exact_synonym: 6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate
 related_synonym: Formula=C27H29F3O6S;   GSK 685698;   InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1;   InChIKey=XTULMSXFIHGYFS-VLSRWLAYSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@](OC(=O)c3ccco3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   Veramyst;   fluticasonum furoas;   furoate de fluticasone;   furoato de fluticasona
 xref: CAS:397864-44-7;   Drug_Central:4554;   KEGG:D06315;   PDBeChem:GW6;   PMID:21828231;   PMID:22170807;   PMID:22342538;   PMID:22387656;   PMID:22391079;   PMID:22614920;   PMID:22738148;   PMID:23018908;   PMID:23116485;   PMID:23184737;   PMID:23200625;   PMID:23332861;   PMID:23352226;   PMID:23406601;   PMID:23440247;   PMID:23548539;   PMID:23578031;   PMID:23676578;   PMID:23719680;   PMID:23735179;   PMID:23806459;   PMID:23821392;   PMID:23846316;   Patent:US2009118495;   Patent:WO2010016931;   Patent:WO2011151624;   Patent:WO2011151625;   Patent:WO2012160338;   Reaxys:15686794;   Wikipedia:Fluticasone_furoate


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        anti-asthmatic agent 9173
          anti-asthmatic drug 8546
            fluticasone furoate 0
              Breo Ellipta 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      carboxylic acid 17978
                                        monocarboxylic acid 17287
                                          furoic acid 17
                                            2-furoic acid 17
                                              2-furoate ester 16
                                                fluticasone furoate 0
                                                  Breo Ellipta 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.