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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluticasone furoate
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Accession:CHEBI:74899 term browser browse the term
Definition:A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease.
Synonyms:exact_synonym: 6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate
 related_synonym: Formula=C27H29F3O6S;   GSK 685698;   InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1;   InChIKey=XTULMSXFIHGYFS-VLSRWLAYSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@](OC(=O)c3ccco3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   Veramyst;   fluticasonum furoas;   furoate de fluticasone;   furoato de fluticasona
 xref: CAS:397864-44-7;   Drug_Central:4554;   KEGG:D06315;   PDBeChem:GW6;   PMID:21828231;   PMID:22170807;   PMID:22342538;   PMID:22387656;   PMID:22391079;   PMID:22614920;   PMID:22738148;   PMID:23018908;   PMID:23116485;   PMID:23184737;   PMID:23200625;   PMID:23332861;   PMID:23352226;   PMID:23406601;   PMID:23440247;   PMID:23548539;   PMID:23578031;   PMID:23676578;   PMID:23719680;   PMID:23735179;   PMID:23806459;   PMID:23821392;   PMID:23846316;   Patent:US2009118495;   Patent:WO2010016931;   Patent:WO2011151624;   Patent:WO2011151625;   Patent:WO2012160338;   Reaxys:15686794;   Wikipedia:Fluticasone_furoate



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19863
    role 19835
      application 19677
        anti-asthmatic agent 9307
          anti-asthmatic drug 8682
            fluticasone furoate 0
              Breo Ellipta 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19863
    subatomic particle 19861
      composite particle 19861
        hadron 19861
          baryon 19861
            nucleon 19861
              atomic nucleus 19861
                atom 19861
                  main group element atom 19807
                    p-block element atom 19807
                      carbon group element atom 19748
                        carbon atom 19744
                          organic molecular entity 19744
                            heteroorganic entity 19498
                              organochalcogen compound 19259
                                organooxygen compound 19175
                                  carbon oxoacid 18642
                                    carboxylic acid 18639
                                      monocarboxylic acid 18012
                                        furoic acid 18
                                          2-furoic acid 18
                                            2-furoate ester 17
                                              fluticasone furoate 0
                                                Breo Ellipta 0
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