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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluticasone furoate
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Accession:CHEBI:74899 term browser browse the term
Definition:A trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease.
Synonyms:exact_synonym: 6alpha,9-difluoro-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-11beta-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17alpha-yl 2-furoate
 related_synonym: Formula=C27H29F3O6S;   GSK 685698;   InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1;   InChIKey=XTULMSXFIHGYFS-VLSRWLAYSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@](OC(=O)c3ccco3)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   Veramyst;   fluticasonum furoas;   furoate de fluticasone;   furoato de fluticasona
 xref: CAS:397864-44-7;   Drug_Central:4554;   KEGG:D06315;   PDBeChem:GW6;   PMID:21828231;   PMID:22170807;   PMID:22342538;   PMID:22387656;   PMID:22391079;   PMID:22614920;   PMID:22738148;   PMID:23018908;   PMID:23116485;   PMID:23184737;   PMID:23200625;   PMID:23332861;   PMID:23352226;   PMID:23406601;   PMID:23440247;   PMID:23548539;   PMID:23578031;   PMID:23676578;   PMID:23719680;   PMID:23735179;   PMID:23806459;   PMID:23821392;   PMID:23846316;   Patent:US2009118495;   Patent:WO2010016931;   Patent:WO2011151624;   Patent:WO2011151625;   Patent:WO2012160338;   Reaxys:15686794;   Wikipedia:Fluticasone_furoate

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Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    role 20009
      application 19747
        anti-asthmatic agent 9254
          anti-asthmatic drug 8620
            fluticasone furoate 0
              Breo Ellipta 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic group 18943
                              organic divalent group 18928
                                organodiyl group 18928
                                  carbonyl group 18877
                                    carbonyl compound 18877
                                      carboxylic acid 18565
                                        monocarboxylic acid 17748
                                          furoic acid 18
                                            2-furoic acid 18
                                              2-furoate ester 17
                                                fluticasone furoate 0
                                                  Breo Ellipta 0
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