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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:natamycin
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Accession:CHEBI:7488 term browser browse the term
Definition:A macrolide antibiotic that has formula C33H47NO13, produced by several Streptomyces species including Streptomyces natalensis. It exhibits broad spectrum antifungal activity and used in eye drops, and as a food preservative, and also as a postharvest biofungicide for citrus and other fruit crops.
Synonyms:exact_synonym: (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0(5,7)]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
 related_synonym: CL 12,625;   CL 12625;   Delvocid;   Delvolan;   Delvopos;   E 235;   Formula=C33H47NO13;   InChI=1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32?,33-/m1/s1;   InChIKey=NCXMLFZGDNKEPB-FFPOYIOWSA-N;   Mycophyt;   Myprozine;   Natacyn;   Natajen;   Natamatrix;   Natamax;   Pimaricin;   Pimarizin;   SMILES=[H][C@@]12C[C@H](O)C[C@]3(O)C[C@H](O)[C@@H](C(O)=O)[C@]([H])(C[C@@H](O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O)\\C=C\\C=C\\C=C\\C=C\\C[C@@H](C)OC(=O)\\C=C\\[C@H]1O2)O3;   Synogil;   antibiotic A-5283;   myuprozine;   natamicina;   natamycine;   natamycinum;   pimafucin;   pimaricine;   tennecetin
 xref: AGR:IND607246306;   AGR:IND607253996;   BPDB:2062;   CAS:7681-93-8;   Chemspider:10468784;   DrugBank:DB00826;   Drug_Central:1885;   FooDB:FDB002337;   HMDB:HMDB0014964;   KEGG:C08073;   KEGG:D00884
 xref_mesh: MESH:D010866
 xref: MetaCyc:CPD-17213;   PMID:18165687;   PMID:30562337;   PMID:31311527;   PMID:32382679;   PMID:32650062;   PMID:32891143;   PMID:33306429;   PMID:33320038;   PMID:33653522;   PMID:33737097;   PMID:33748084;   PMID:33822660;   PMID:33882328;   PMID:33973428;   PMID:34085850;   PMID:34311233;   PMID:34428517;   PMID:34515597;   PMID:34571612;   PMID:34574183;   Pesticides:natamycin;   Wikipedia:Natamycin


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natamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin increases expression ISO Natamycin results in increased expression of CLU mRNA CTD PMID:22863853 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cp ceruloplasmin increases expression ISO Natamycin results in increased expression of CP mRNA CTD PMID:22863853 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Fga fibrinogen alpha chain increases expression ISO Natamycin results in increased expression of FGA mRNA CTD PMID:22863853 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Natamycin results in increased expression of FGG mRNA CTD PMID:22863853 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Natamycin results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Krt19 keratin 19 increases expression ISO Natamycin results in increased expression of KRT19 mRNA CTD PMID:22863853 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Natamycin results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Natamycin results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Natamycin results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20039
    role 19990
      biological role 19989
        antimicrobial agent 17748
          macrolide antibiotic 397
            natamycin 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20039
    subatomic particle 20037
      composite particle 20037
        hadron 20037
          baryon 20037
            nucleon 20037
              atomic nucleus 20037
                atom 20037
                  main group element atom 19938
                    p-block element atom 19938
                      carbon group element atom 19861
                        carbon atom 19852
                          organic molecular entity 19852
                            organic group 18932
                              organic divalent group 18916
                                organodiyl group 18916
                                  carbonyl group 18865
                                    carbonyl compound 18865
                                      carboxylic ester 15945
                                        lactone 11280
                                          macrocyclic lactone 5588
                                            macrolide 5541
                                              macrolide antibiotic 397
                                                natamycin 9
paths to the root