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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antimony trichloride
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Accession:CHEBI:74856 term browser browse the term
Definition:An inorganic chloride salt with formula SbCl3. It is used as a reagent for detecting vitamin A and related carotenoids, reacting with the carotenoid to form a blue complex that can be measured by colorimetry (the Carr-Price test). Solutions of antimony trichloride were formerly used for dissolving and removing horn stubs from calves and goats.
Synonyms:exact_synonym: trichlorostibane
 related_synonym: Antimontrichlorid;   Formula=Cl3Sb;   InChI=1S/3ClH.Sb/h3*1H;/q;;;+3/p-3;   InChIKey=FAPDDOBMIUGHIN-UHFFFAOYSA-K;   SMILES=Cl[Sb](Cl)Cl;   SbCl3;   Trichlorostibine;   antimony butter;   antimony chloride;   antimony(III) chloride;   antimony(III) trichloride;   butter of antimony;   caustic antimony;   chlorure antimonieux;   trichloridoantimony;   trichlorure d'antimoine
 xref: CAS:10025-91-9;   KEGG:C15235
 xref_mesh: MESH:C054672
 xref: PMID:1021254;   PMID:1021287;   PMID:1451533;   PMID:15423457;   PMID:17618378;   PMID:17719894;   PMID:18964394;   PMID:19370932;   PMID:2893463;   PMID:29107181;   PMID:4338731;   PMID:5924140;   PMID:663961;   PMID:9657841;   PMID:9772090;   PMID:9903480;   Reaxys:3600276;   Wikipedia:Antimony_trichloride


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antimony trichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases cleavage ISO antimony trichloride results in increased cleavage of CASP3 protein CTD PMID:30055241 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein CTD PMID:20509621 NCBI chr 1:226,657,561...226,683,356
Ensembl chr 1:226,657,561...226,683,347
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO antimony trichloride results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein]
CTD PMID:30055241 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO antimony trichloride results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein]
CTD PMID:30055241 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions
ISO antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]
CTD PMID:30055241 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions
affects binding
ISO antimony trichloride inhibits the reaction [XPA protein binds to Zinc]
antimony trichloride binds to XPA protein
CTD PMID:20509621 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      chemical role 19262
        acceptor 17044
          Lewis acid 3505
            antimony trichloride 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      halogen 18108
                        chlorine atom 17927
                          chlorine molecular entity 17927
                            elemental chlorine 8444
                              monoatomic chlorine 8427
                                chloride 8427
                                  chloride salt 8427
                                    inorganic chloride 8265
                                      antimony trichloride 6
paths to the root