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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antimony trichloride
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Accession:CHEBI:74856 term browser browse the term
Definition:An inorganic chloride salt with formula SbCl3. It is used as a reagent for detecting vitamin A and related carotenoids, reacting with the carotenoid to form a blue complex that can be measured by colorimetry (the Carr-Price test). Solutions of antimony trichloride were formerly used for dissolving and removing horn stubs from calves and goats.
Synonyms:exact_synonym: trichlorostibane
 related_synonym: Antimontrichlorid;   Formula=Cl3Sb;   InChI=1S/3ClH.Sb/h3*1H;/q;;;+3/p-3;   InChIKey=FAPDDOBMIUGHIN-UHFFFAOYSA-K;   SMILES=Cl[Sb](Cl)Cl;   SbCl3;   Trichlorostibine;   antimony butter;   antimony chloride;   antimony(III) chloride;   antimony(III) trichloride;   butter of antimony;   caustic antimony;   chlorure antimonieux;   trichloridoantimony;   trichlorure d'antimoine
 xref: CAS:10025-91-9;   KEGG:C15235
 xref_mesh: MESH:C054672
 xref: PMID:1021254;   PMID:1021287;   PMID:1451533;   PMID:15423457;   PMID:17618378;   PMID:17719894;   PMID:18964394;   PMID:19370932;   PMID:2893463;   PMID:29107181;   PMID:4338731;   PMID:5924140;   PMID:663961;   PMID:9657841;   PMID:9772090;   PMID:9903480;   Reaxys:3600276;   Wikipedia:Antimony_trichloride



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antimony trichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases cleavage ISO antimony trichloride results in increased cleavage of CASP3 protein CTD PMID:30055241 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 decreases expression ISO antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein CTD PMID:20509621 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO antimony trichloride results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein]
CTD PMID:30055241 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO antimony trichloride results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein]
CTD PMID:30055241 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions
ISO antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein
Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]
CTD PMID:30055241 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions
affects binding
ISO antimony trichloride inhibits the reaction [XPA protein binds to Zinc]
antimony trichloride binds to XPA protein
CTD PMID:20509621 NCBI chr 5:60,431,673...60,476,438
Ensembl chr 5:60,431,673...60,475,726
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      chemical role 19320
        acceptor 17316
          Lewis acid 3565
            antimony trichloride 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      halogen 18184
                        chlorine atom 18027
                          chlorine molecular entity 18027
                            elemental chlorine 8463
                              monoatomic chlorine 8447
                                chloride 8447
                                  chloride salt 8447
                                    inorganic chloride 8278
                                      antimony trichloride 6
paths to the root