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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antidote to curare poisoning
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Accession:CHEBI:74530 term browser browse the term
Definition:A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare.
Synonyms:related_synonym: antidote to curare;   antidote to tubocurarine;   antidote to tubocurarine poisoning;   antidotes to curare;   antidotes to curare poisoning;   antidotes to tubocurarine;   antidotes to tubocurarine poisoning;   curare antidote;   curare antidotes;   curare poisoning antidote;   curare poisoning antidotes;   tubocurarine antidote;   tubocurarine antidotes
 xref: PMID:13358565;   PMID:13386996;   PMID:14128111;   PMID:1579914;   PMID:3896015;   PMID:5333582;   PMID:5352084;   PMID:7720787



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(R)-pantothenic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atoh8 atonal bHLH transcription factor 8 increases expression ISO Pantothenic Acid results in increased expression of ATOH8 mRNA CTD PMID:19397697 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid] CTD PMID:24709313 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Pantothenic Acid results in increased expression of CYP1B1 mRNA CTD PMID:19397697 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO Pantothenic Acid results in increased expression of FAM43A mRNA CTD PMID:19397697 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
JBrowse link
G Fut7 fucosyltransferase 7 decreases expression ISO Pantothenic Acid results in decreased expression of FUT7 mRNA CTD PMID:19397697 NCBI chr 3:8,237,687...8,242,273
Ensembl chr 3:8,239,384...8,242,260
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Pantothenic Acid results in increased expression of HMOX1 mRNA; Pantothenic Acid results in increased expression of HMOX1 protein CTD PMID:19397697 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 increases expression ISO Pantothenic Acid results in increased expression of HSPB7 mRNA CTD PMID:19397697 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Pantothenic Acid results in increased expression of ID1 mRNA CTD PMID:19397697 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Pantothenic Acid results in increased expression of ID3 mRNA CTD PMID:19397697 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of Pantothenic Acid
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Pantothenic Acid]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Il6 interleukin 6 increases expression ISO Pantothenic Acid results in increased expression of IL6 mRNA CTD PMID:19397697 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Pantothenic Acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Marchf2 membrane associated ring-CH-type finger 2 increases expression ISO Pantothenic Acid results in increased expression of MARCHF2 mRNA CTD PMID:19397697 NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794
JBrowse link
G Mtres1 mitochondrial transcription rescue factor 1 increases expression ISO Pantothenic Acid results in increased expression of MTRES1 mRNA CTD PMID:19397697 NCBI chr20:47,022,343...47,038,888
Ensembl chr20:47,022,342...47,038,805
JBrowse link
G Myb MYB proto-oncogene, transcription factor multiple interactions ISO Pantothenic Acid inhibits the reaction [Valproic Acid results in decreased expression of MYB protein] CTD PMID:16112698 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor increases expression ISO Pantothenic Acid results in increased expression of MYCN mRNA CTD PMID:19397697 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Nhlrc1 NHL repeat containing E3 ubiquitin protein ligase 1 increases expression ISO Pantothenic Acid results in increased expression of NHLRC1 mRNA CTD PMID:19397697 NCBI chr17:17,674,375...17,675,565
Ensembl chr17:17,674,319...17,677,148
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA CTD PMID:20505214 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrep neuronal regeneration related protein increases expression ISO Pantothenic Acid results in increased expression of NREP mRNA CTD PMID:19397697 NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase multiple interactions ISO Pantothenic Acid inhibits the reaction [Valproic Acid results in decreased expression of PIM1 protein] CTD PMID:16112698 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pou3f4 POU class 3 homeobox 4 increases expression ISO Pantothenic Acid results in increased expression of POU3F4 mRNA CTD PMID:19397697 NCBI chr  X:75,858,646...75,859,923
Ensembl chr  X:75,858,646...75,859,923
JBrowse link
G Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein increases expression ISO Pantothenic Acid results in increased expression of PTPRCAP mRNA CTD PMID:19397697 NCBI chr 1:201,449,133...201,451,293
Ensembl chr 1:201,449,113...201,451,288
JBrowse link
G Slc51b solute carrier family 51 subunit beta increases expression ISO Pantothenic Acid results in increased expression of SLC51B mRNA CTD PMID:19397697 NCBI chr 8:65,931,891...65,934,893
Ensembl chr 8:65,931,890...65,940,145
JBrowse link
G Slc5a6 solute carrier family 5 member 6 increases transport
multiple interactions
EXP
ISO
SLC5A6 results in increased transport of Pantothenic Acid
Sodium affects the reaction [SLC5A6 results in increased transport of Pantothenic Acid]
Thioctic Acid inhibits the reaction [SLC5A6 results in increased transport of Pantothenic Acid]
CTD PMID:9516450 PMID:10329687 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO Pantothenic Acid results in decreased expression of SOX2 mRNA CTD PMID:19397697 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Tmem18 transmembrane protein 18 increases expression ISO Pantothenic Acid results in increased expression of TMEM18 mRNA CTD PMID:19397697 NCBI chr 6:47,206,845...47,214,294
Ensembl chr 6:47,206,845...47,214,294
JBrowse link
G Zfp575 zinc finger protein 575 decreases expression ISO Pantothenic Acid results in decreased expression of ZNF575 mRNA CTD PMID:19397697 NCBI chr 1:80,175,016...80,177,176
Ensembl chr 1:80,175,016...80,177,123
JBrowse link
galanthamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
multiple interactions
EXP
ISO
Galantamine results in decreased activity of ACHE protein
Galantamine inhibits the reaction [Scopolamine results in increased activity of ACHE protein]
Galantamine binds to and results in decreased activity of ACHE protein; Galantamine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine inhibits the reaction [Obidoxime Chloride metabolite results in decreased activity of ACHE protein]; Galantamine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]
CTD PMID:14535624 PMID:18571635 PMID:18573242 PMID:19345205 PMID:25522658 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Galantamine inhibits the reaction [APP protein modified form results in decreased expression of CHRNA7 protein]; methyllycaconitine inhibits the reaction [Galantamine inhibits the reaction [APP protein modified form results in decreased expression of CHRNA7 protein]] CTD PMID:25881725 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Bche butyrylcholinesterase decreases activity EXP
ISO
Galantamine results in decreased activity of BCHE protein CTD PMID:19345205 PMID:29886234 PMID:31125207 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Ces2h carboxylesterase 2H decreases activity ISO Galantamine results in decreased activity of CES2 protein CTD PMID:23123248 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP Galantamine results in decreased expression of CHRM1 protein CTD PMID:28837785 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit affects binding
multiple interactions
ISO Galantamine binds to [CHRNA4 protein binds to CHRNB2 protein]
Galantamine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO Galantamine inhibits the reaction [APP protein modified form results in decreased expression of CHRNA7 protein]; methyllycaconitine inhibits the reaction [Galantamine inhibits the reaction [APP protein modified form results in decreased expression of CHRNA7 protein]] CTD PMID:25881725 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO Galantamine binds to [CHRNA4 protein binds to CHRNB2 protein]
Galantamine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
neostigmine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Neostigmine results in decreased activity of ACHE protein CTD PMID:623676 PMID:19105816 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bche butyrylcholinesterase affects response to substance ISO BCHE affects the susceptibility to Neostigmine CTD PMID:18399847 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Il10 interleukin 10 increases expression EXP Neostigmine results in increased expression of IL10 protein CTD PMID:17872965 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Pygl glycogen phosphorylase L increases activity
multiple interactions
EXP Neostigmine results in increased activity of PYGL protein modified form
Phentolamine inhibits the reaction [Neostigmine results in increased activity of PYGL protein modified form]
CTD PMID:1350317 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Tnf tumor necrosis factor decreases expression EXP Neostigmine results in decreased expression of TNF protein CTD PMID:17872965 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
physostigmine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase multiple interactions ISO Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifabutin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine] CTD PMID:21856291 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
JBrowse link
G Ache acetylcholinesterase decreases activity
affects expression
multiple interactions
increases expression
ISO
EXP
Physostigmine results in decreased activity of ACHE protein
Physostigmine affects the expression of ACHE mRNA
[Corticosterone co-treated with Physostigmine] results in decreased activity of ACHE protein; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
[Physostigmine co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]] which results in decreased carbamoylation of ACHE protein; ALB protein affects the reaction [Physostigmine results in decreased activity of ACHE protein]; Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]
asoxime chloride affects the reaction [Physostigmine results in decreased activity of ACHE protein]; asoxime chloride promotes the reaction [Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]]; Physostigmine affects the expression of and affects the activity of ACHE protein; Physostigmine affects the reaction [Sarin affects the expression of ACHE mRNA]; Physostigmine affects the reaction [Sarin affects the expression of and affects the activity of ACHE protein]; Physostigmine inhibits the reaction [Soman results in decreased activity of ACHE protein]
Physostigmine results in increased expression of ACHE protein
CTD PMID:4859365 PMID:11740913 PMID:14644616 PMID:15586889 PMID:19283689 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Alb albumin multiple interactions ISO ALB protein affects the reaction [Physostigmine results in decreased activity of ACHE protein] CTD PMID:26902639 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G App amyloid beta precursor protein increases secretion EXP Physostigmine results in increased secretion of APP protein modified form CTD PMID:7605915 PMID:8624119 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions
EXP
ISO
Physostigmine results in decreased activity of BCHE protein
Physostigmine inhibits the reaction [Sarin results in decreased activity of BCHE protein]
CTD PMID:19283689 PMID:32795450 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Physostigmine inhibits the reaction [Corticosterone results in decreased expression of CCL2 mRNA] CTD PMID:28500787 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ces2h carboxylesterase 2H decreases activity ISO Physostigmine results in decreased activity of CES2 protein CTD PMID:9169443 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Chat choline O-acetyltransferase decreases expression
increases expression
EXP Physostigmine results in decreased expression of CHAT protein
Physostigmine results in increased expression of CHAT protein
CTD PMID:22640809 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit affects binding
multiple interactions
ISO Physostigmine binds to [CHRNA4 protein binds to CHRNB2 protein]
Physostigmine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Physostigmine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Physostigmine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]; Physostigmine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:14645658 PMID:15733544 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO Physostigmine binds to [CHRNA4 protein binds to CHRNB2 protein]
Physostigmine binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; Physostigmine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Physostigmine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]; Physostigmine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]
CTD PMID:14645658 PMID:15733544 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO Physostigmine inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] CTD PMID:24555085 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Physostigmine inhibits the reaction [Scopolamine promotes the reaction [SK&F 82958 results in increased expression of FOS mRNA]]; Physostigmine inhibits the reaction [SK&F 82958 results in increased expression of FOS mRNA] CTD PMID:11337201 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein] CTD PMID:28499986 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Hmox1 heme oxygenase 1 affects expression EXP Physostigmine affects the expression of HMOX1 mRNA CTD PMID:22954530 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine] CTD PMID:8539317 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Physostigmine affects the reaction [Corticosterone affects the expression of IL1B mRNA] CTD PMID:28500787 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Corticosterone co-treated with Physostigmine] results in decreased expression of IL6 mRNA CTD PMID:28500787 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Physostigmine inhibits the reaction [Scopolamine promotes the reaction [SK&F 82958 results in increased expression of JUN mRNA]]; Physostigmine inhibits the reaction [SK&F 82958 results in increased expression of JUN mRNA] CTD PMID:11337201 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO [Corticosterone co-treated with Physostigmine] results in decreased expression of LIF mRNA CTD PMID:28500787 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO Physostigmine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein] CTD PMID:28499986 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO Physostigmine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein] CTD PMID:28499986 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Osm oncostatin M multiple interactions ISO [Corticosterone co-treated with Physostigmine] results in increased expression of OSM mRNA CTD PMID:28500787 PMID:29846716 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Slc18a3 solute carrier family 18 member A3 increases expression EXP Physostigmine results in increased expression of SLC18A3 protein CTD PMID:22640809 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CTD PMID:28499986 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO Physostigmine results in decreased phosphorylation of STAT3 protein CTD PMID:28500787 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Syp synaptophysin multiple interactions ISO Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SYP protein] CTD PMID:28499986 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Corticosterone co-treated with Physostigmine] results in increased expression of TNF mRNA CTD PMID:28500787 PMID:29846716 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
physostigmine salicylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO physostigmine salicylate results in decreased activity of ACHE protein CTD PMID:623676 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        pharmaceutical 19356
          drug 19356
            protective agent 17739
              antidote 7681
                antidote to curare poisoning 56
                  (R)-pantothenic acid + 27
                  galanthamine 8
                  neostigmine + 5
                  physostigmine + 27
paths to the root