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Accession:CHEBI:7451 term browser browse the term
Definition:A tertiary amine in which the nitrogen is substituted by methyl, alpha-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections.
Synonyms:exact_synonym: (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenylprop-2-en-1-amine
 related_synonym: (E)-N-cinnamyl-N-methyl-1-naphthalenemethylamine;   Formula=C21H21N;   InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3/b11-8+;   InChIKey=OZGNYLLQHRPOBR-DHZHZOJOSA-N;   SMILES=CN(C\\C=C\\c1ccccc1)Cc1cccc2ccccc12;   naftifin;   naftifina;   naftifinum;   trans-N-cinnamyl-N-methyl-(1-naphthylmethyl)amine
 xref: CAS:65472-88-0 "ChemIDplus";   CAS:65472-88-0 "KEGG COMPOUND";   DrugBank:DB00735;   Drug_Central:1872 "DrugCentral";   HMDB:HMDB0014873;   KEGG:C08071;   KEGG:D08245
 xref_mesh: MESH:C029178
 xref: PMID:18212112 "Europe PMC";   PMID:24196340 "Europe PMC";   PMID:25294700 "Europe PMC";   PMID:6388170 "Europe PMC";   Patent:BE853976;   Patent:US4282251;   Reaxys:2983617 "Reaxys";   Wikipedia:Naftifine

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naftifine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        inhibitor 18055
          sterol biosynthesis inhibitor 2894
            naftifine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    main group molecular entity 19534
                      s-block molecular entity 19319
                        hydrogen molecular entity 19310
                          hydrides 18237
                            inorganic hydride 17105
                              pnictogen hydride 17063
                                nitrogen hydride 16886
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8522
                                          tertiary amine 599
                                            naftifine 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.