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ONTOLOGY REPORT - ANNOTATIONS


Term:nafcillin
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Accession:CHEBI:7447 term browser browse the term
Definition:A penicillin in which the substituent at position 6 of the penam ring is a (2-ethoxy-1-naphthoyl)amino group.
Synonyms:exact_synonym: 6beta-(2-ethoxynaphthalene-1-carboxamido)-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2-ethoxy-1-naphthalenyl)penicillin;   (2-ethoxy-1-naphthyl)penicillin;   (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   (2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   (2S,5R,6R)-6-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   6-(2-ethoxy-1-naphthamido)penicillanic acid;   Formula=C21H22N2O5S;   InChI=1S/C21H22N2O5S/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27)/t15-,16+,19-/m1/s1;   InChIKey=GPXLMGHLHQJAGZ-JTDSTZFVSA-N;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(OCC)ccc2ccccc12)C(O)=O;   nafcilina;   nafcilline;   nafcillinum;   naphcillin
 alt_id: CHEBI:44256
 xref: Beilstein:5405727 "Beilstein";   CAS:147-52-4 "ChemIDplus";   CAS:147-52-4 "KEGG COMPOUND";   DrugBank:DB00607;   Drug_Central:1869 "DrugCentral";   KEGG:C07250;   KEGG:D08242;   LINCS:LSM-2402
 xref_mesh: MESH:D009254
 xref: PMID:29017833 "Europe PMC";   Patent:GB880400;   Patent:US3157639;   Patent:US3506645;   Reaxys:5405727 "Reaxys";   Wikipedia:Nafcillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:51918


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nafcillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        aetiopathogenetic role 18782
          allergen 16866
            penicillin 260
              nafcillin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        carboacyl group 17074
                                          univalent carboacyl group 17074
                                            carbamoyl group 16804
                                              carboxamide 16804
                                                lactam 7818
                                                  beta-lactam 786
                                                    beta-lactam antibiotic 774
                                                      penams 260
                                                        penicillanic acids 260
                                                          penicillanic acid 260
                                                            6-aminopenicillanic acid 260
                                                              penicillin 260
                                                                penicillin allergen 257
                                                                  nafcillin 1
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