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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-chloro-7-iodoquinolin-8-ol
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Accession:CHEBI:74460 term browser browse the term
Definition:A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Synonyms:related_synonym: 5-Chlor-7-jod-8-hydroxy-chinolin;   5-chloro-7-iodo-8-hydroxyquinoline;   5-chloro-7-iodo-8-quinolinol;   5-chloro-8-hydroxy-7-iodoquinoline;   7-iodo-5-chloroxine;   Formula=C9H5ClINO;   InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H;   InChIKey=QCDFBFJGMNKBDO-UHFFFAOYSA-N;   SMILES=Oc1c(I)cc(Cl)c2cccnc12;   chloroiodoquin;   clioquinol;   clioquinolum;   iodochlorhydroxyquinoline;   iodochlorohydroxyquin;   iodochloroxyquinoline
 xref: CAS:130-26-7;   DrugBank:DB04815;   Drug_Central:681;   KEGG:D03538;   LINCS:LSM-2186
 xref_mesh: MESH:D007464
 xref: PDBeChem:CQL;   PMID:15074181;   PMID:15651505;   PMID:16087879;   PMID:185949;   PMID:20651355;   PMID:21080020;   PMID:21199452;   PMID:21247386;   PMID:21426304;   PMID:21899946;   PMID:22248233;   PMID:22269164;   PMID:22627294;   PMID:226725;   PMID:23044228;   PMID:23360710;   PMID:23627708;   Patent:DE117767;   Patent:US641491;   Reaxys:153637;   Wikipedia:Clioquinol


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Term Annotations click to browse term
  CHEBI ontology 5066
    role 5030
      biological role 5030
        antimicrobial agent 257
          5-chloro-7-iodoquinolin-8-ol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5066
    subatomic particle 5057
      composite particle 5057
        hadron 5057
          baryon 5057
            nucleon 5057
              atomic nucleus 5057
                atom 5057
                  main group element atom 5026
                    p-block element atom 5023
                      carbon group element atom 4940
                        carbon atom 4939
                          organic molecular entity 4939
                            organic molecule 4887
                              organic cyclic compound 4825
                                organic heterocyclic compound 4614
                                  organonitrogen heterocyclic compound 267
                                    quinolines 17
                                      hydroxyquinoline 0
                                        monohydroxyquinoline 0
                                          5-chloro-7-iodoquinolin-8-ol 0
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