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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-chloro-7-iodoquinolin-8-ol
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Accession:CHEBI:74460 term browser browse the term
Definition:A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Synonyms:related_synonym: 5-Chlor-7-jod-8-hydroxy-chinolin;   5-chloro-7-iodo-8-hydroxyquinoline;   5-chloro-7-iodo-8-quinolinol;   5-chloro-8-hydroxy-7-iodoquinoline;   7-iodo-5-chloroxine;   Formula=C9H5ClINO;   InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H;   InChIKey=QCDFBFJGMNKBDO-UHFFFAOYSA-N;   SMILES=Oc1c(I)cc(Cl)c2cccnc12;   chloroiodoquin;   clioquinol;   clioquinolum;   iodochlorhydroxyquinoline;   iodochlorohydroxyquin;   iodochloroxyquinoline
 xref: CAS:130-26-7;   DrugBank:DB04815;   Drug_Central:681;   KEGG:D03538;   LINCS:LSM-2186
 xref_mesh: MESH:D007464
 xref: PDBeChem:CQL;   PMID:15074181;   PMID:15651505;   PMID:16087879;   PMID:185949;   PMID:20651355;   PMID:21080020;   PMID:21199452;   PMID:21247386;   PMID:21426304;   PMID:21899946;   PMID:22248233;   PMID:22269164;   PMID:22627294;   PMID:226725;   PMID:23044228;   PMID:23360710;   PMID:23627708;   Patent:DE117767;   Patent:US641491;   Reaxys:153637;   Wikipedia:Clioquinol

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  CHEBI ontology 0
    role 0
      biological role 0
        antimicrobial agent 0
          5-chloro-7-iodoquinolin-8-ol 0
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Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic molecule 0
                              organic cyclic compound 0
                                organic heterocyclic compound 0
                                  organonitrogen heterocyclic compound 0
                                    quinolines 0
                                      hydroxyquinoline 0
                                        monohydroxyquinoline 0
                                          5-chloro-7-iodoquinolin-8-ol 0
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