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ONTOLOGY REPORT - ANNOTATIONS


Term:pyrrolidin-2-ones
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Accession:CHEBI:74223 term browser browse the term
Definition:A pyrrolidinone in which the oxo group is at position 2 of the pyrrolidine ring.
Synonyms:related_synonym: 2-pyrrolidinones;   2-pyrrolidones;   Formula=C4NOR7;   SMILES=[*]N1C(=O)C([*])([*])C([*])([*])C1([*])[*];   pyrrolidine-2-ones


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(-)-cotinine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahrr aryl-hydrocarbon receptor repressor JBrowse link 1 31,603,297 31,698,329 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Cd68 Cd68 molecule JBrowse link 10 56,268,726 56,270,605 RGD:6480464
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:6480464
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:6480464
G Cntnap2 contactin associated protein-like 2 JBrowse link 4 74,700,539 77,025,463 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Ext1 exostosin glycosyltransferase 1 JBrowse link 7 92,605,008 92,881,392 RGD:6480464
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Myo1g myosin IG JBrowse link 14 86,781,243 86,796,393 RGD:6480464
G Nat1 N-acetyltransferase 1 JBrowse link 16 23,970,742 23,991,573 RGD:6480464
G Pnpla2 patatin-like phospholipase domain containing 2 JBrowse link 1 214,434,638 214,439,720 RGD:6480464
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Ttc7b tetratricopeptide repeat domain 7B JBrowse link 6 124,316,444 124,528,058 RGD:6480464
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 JBrowse link 9 95,256,628 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
5-oxo-L-proline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
aniracetam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:6480464
doxapram term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
levetiracetam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Acvrl1 activin A receptor like type 1 JBrowse link 7 142,769,942 142,787,336 RGD:6480464
G Arhgef1 Rho guanine nucleotide exchange factor 1 JBrowse link 1 81,769,212 81,797,237 RGD:6480464
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 JBrowse link 10 85,954,138 85,974,764 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccnh cyclin H JBrowse link 2 13,593,100 13,613,910 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:6480464
G Dbp D-box binding PAR bZIP transcription factor JBrowse link 1 101,687,896 101,692,845 RGD:6480464
G Des desmin JBrowse link 9 82,556,574 82,564,288 RGD:6480464
G Gle1 GLE1 RNA export mediator JBrowse link 3 8,498,098 8,530,218 RGD:6480464
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 JBrowse link 7 12,851,730 12,870,087 RGD:6480464
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:6480464
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:6480464
G Kcna4 potassium voltage-gated channel subfamily A member 4 JBrowse link 3 98,293,295 98,300,763 RGD:6480464
G Kctd3 potassium channel tetramerization domain containing 3 JBrowse link 13 107,433,588 107,471,843 RGD:6480464
G Khdrbs2 KH RNA binding domain containing, signal transduction associated 2 JBrowse link 9 39,501,431 40,008,707 RGD:6480464
G Lap3 leucine aminopeptidase 3 JBrowse link 14 70,102,813 70,121,797 RGD:6480464
G Lsm1 LSM1 homolog, mRNA degradation associated JBrowse link 16 71,046,475 71,057,883 RGD:6480464
G Mettl7b methyltransferase like 7B JBrowse link 7 3,383,876 3,386,522 RGD:6480464
G Nap1l2 nucleosome assembly protein 1-like 2 JBrowse link X 73,997,274 73,999,677 RGD:6480464
G Ngly1 N-glycanase 1 JBrowse link 15 10,405,453 10,455,973 RGD:6480464
G Phldb1 pleckstrin homology-like domain, family B, member 1 JBrowse link 8 48,997,189 49,045,176 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464
G Prkx protein kinase, X-linked JBrowse link X 45,080,963 45,125,095 RGD:6480464
G Psip1 PC4 and SFRS1 interacting protein 1 JBrowse link 5 101,555,691 101,588,659 RGD:6480464
G Serinc1 serine incorporator 1 JBrowse link 20 38,966,016 38,985,056 RGD:6480464
G Slc23a2 solute carrier family 23 member 2 JBrowse link 3 124,632,491 124,842,225 RGD:6480464
G Slc4a7 solute carrier family 4 member 7 JBrowse link 15 11,832,611 11,912,923 RGD:6480464
G Smc2 structural maintenance of chromosomes 2 JBrowse link 5 68,717,509 68,764,080 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tent2 terminal nucleotidyltransferase 2 JBrowse link 2 22,746,290 22,798,252 RGD:6480464
G Trdmt1 tRNA aspartic acid methyltransferase 1 JBrowse link 17 80,824,652 80,859,585 RGD:6480464
G Vars2 valyl-tRNA synthetase 2, mitochondrial JBrowse link 20 3,588,462 3,599,514 RGD:6480464
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:6480464
G Zfp266 zinc finger protein 266 JBrowse link 8 21,511,831 21,543,275 RGD:6480464
N-Vinyl-2-pyrrolidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:6480464
G Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link 19 43,932,543 43,967,452 RGD:6480464
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:6480464
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:6480464
G Csnk1d casein kinase 1, delta JBrowse link 10 110,147,786 110,182,413 RGD:6480464
G Csnk1e casein kinase 1, epsilon JBrowse link 7 120,651,976 120,675,559 RGD:6480464
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:6480464
G Csnk2a2 casein kinase 2 alpha 2 JBrowse link 19 9,972,537 10,012,043 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:6480464
G Foxg1 forkhead box G1 JBrowse link 6 69,971,227 69,974,037 RGD:6480464
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:6480464
G Ilk integrin-linked kinase JBrowse link 1 170,578,941 170,585,192 RGD:6480464
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 JBrowse link 16 20,415,109 20,424,982 RGD:6480464
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:6480464
G Slc5a5 solute carrier family 5 member 5 JBrowse link 16 20,297,414 20,307,401 RGD:6480464
G Tcf3 transcription factor 3 JBrowse link 7 12,146,642 12,168,400 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:6480464
G Tpo thyroid peroxidase JBrowse link 6 49,020,918 49,089,855 RGD:6480464
G Tshb thyroid stimulating hormone subunit beta JBrowse link 2 205,207,799 205,215,199 RGD:6480464
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 14 22,724,399 22,736,148 RGD:6480464
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:6480464
rolipram term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:6480464
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Epx eosinophil peroxidase JBrowse link 10 75,160,690 75,171,774 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:6480464
G Pde4a phosphodiesterase 4A JBrowse link 8 22,189,533 22,234,036 RGD:6480464
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:6480464
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:6480464
G Rap1b RAP1B, member of RAS oncogene family JBrowse link 7 60,850,406 60,878,226 RGD:6480464
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:6480464
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:6480464
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      atom 19665
        nonmetal atom 19531
          nitrogen atom 18301
            nitrogen molecular entity 18301
              organonitrogen compound 18076
                organonitrogen heterocyclic compound 16961
                  pyrrolidines 1466
                    pyrrolidinone 158
                      pyrrolidin-2-ones 131
                        (-)-cotinine + 28
                        (1E)-2-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}prop-1-ene-1-sulfonamide 0
                        (2R)-N-hydroxy-2-[(3S)-3-methyl-3-\{4-[(2-methylquinolin-4-yl)methoxy]phenyl\}-2-oxopyrrolidin-1-yl]propanamide 0
                        (2S)-2-[(3S)-3-\{[(6-chloronaphthalen-2-yl)sulfonyl]amino\}-2-oxopyrrolidin-1-yl]-N-(1-methylethyl)-N-\{2-[(methylsulfonyl)amino]ethyl\}propanamide 0
                        (2S)-N-((1S,2R)-2-hydroxy-1-(4-hydroxybenzyl)-3-\{[(8S,11S)-8-[(1S)-1-methylpropyl]-7,10-dioxo-2-oxa-6,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]amino\}propyl)-3-methyl-2-(2-oxopyrrolidin-1-yl)butanamide 0
                        (3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide 0
                        (3S)-3-[(2S)-2-amino-3-hydroxybutyl]pyrrolidin-2-one 0
                        (3S)-3-[(2S)-2-amino-3-oxobutyl]pyrrolidin-2-one 0
                        (3S)-3-[(2S)-2-amino-4-hydroxy-3-oxobutyl]pyrrolidin-2-one 0
                        (3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide 0
                        (3S)-N-(3-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide 0
                        (3S)-N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide 0
                        (3Z)-ravenic acid 0
                        (E)-2-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}ethenesulfonamide 0
                        1,5,5-trimethylpyrrolidin-2-one 0
                        1-(4-carboxy-2-guanidinophenyl)-5,5-bis(hydroxymethyl)pyrrolidin-2-one 0
                        1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one 0
                        2-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}ethanesulfonamide 0
                        3-(\{[(2S)-5-oxopyrrolidin-2-yl]methyl\}sulfonyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alanin[N-(1-cyanocyclopropyl)]amide 0
                        3-nitro-4-(2-oxopyrrolidin-1-yl)benzenesulfonamide 0
                        3-oxo-N-[(3S)-2-oxopyrrolidin-3-yl]dodecanamide 0
                        4-[(2R)-2-(aminomethyl)-2-(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(1-ethylpropyl)amino]benzoic acid 0
                        4-hydroxy-3-[2-oxo-3-(thieno[3,2-b]pyridine-2-sulfonylamino)pyrrolidin-1-ylmethyl]benzamidine 0
                        5-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1H-1,2,4-triazole-3-sulfonamide 0
                        5-\{[(2-amino-9H-purin-6-yl)oxy]methyl\}pyrrolidin-2-one 0
                        5-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1-benzothiophene-2-sulfonamide 0
                        5-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1H-indole-2-sulfonamide 0
                        5-cyclohexylmethyl-2-Pyrrolidinone 0
                        5-oxoproline + 2
                        5-oxopyrrolidine-2-carbaldehyde 0
                        6-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1-benzothiophene-2-sulfonamide 0
                        6-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}naphthalene-2-sulfonamide 0
                        N-(3-acetamidopropyl)pyrrolidin-2-one 0
                        N-(3-furoyl)-D-valyl-L-valyl-N-((1R,2Z)-4-ethoxy-4-oxo-1-\{[(3S)-2-oxopyrrolidin-3-yl]methyl\}but-2-enyl)-D-leucinamide 0
                        N-Vinyl-2-pyrrolidone 30
                        N-[(3S,6R)-6-\{(S,E)-4-ethoxycarbonyl-1-[(S)-2-oxopyrrolidin-3-yl]but-3-en-2-ylcarbamoyl\}-2,9-dimethyl-4-oxodec-8-en-3-yl]-5-methylisoxazole-3-carboxamide 0
                        N-[(5-methylisoxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N(1)-((1S)-4-ethoxy-4-oxo-1-\{[(3S)-2-oxopyrrolidin-3-yl]methyl\}but-2-enyl)-L-leucinamide 0
                        N-[(5-methylisoxazol-3-yl)carbonyl]alanyl-L-valyl-N(1)-((1R,2Z)-4-(benzyloxy)-4-oxo-1-\{[(3R)-2-oxopyrrolidin-3-yl]methyl\}but-2-enyl)-L-leucinamide 0
                        N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-3-cyclohexyl-N-[(1S)-2-hydroxy-1-\{[(3S)-2-oxopyrrolidin-3-yl]methyl\}ethyl]-L-alaninamide 0
                        N-\{(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl\}thieno[3,2-b]pyridine-2-sulfonamide 0
                        N-methylpyrrolidin-2-one 0
                        PHA-533533 0
                        aniracetam 2
                        cotinine N-oxide 0
                        doxapram + 2
                        ethyl (2E,4S)-4-[((2R)-2-\{[N-(tert-butoxycarbonyl)-L-valyl]amino\}-2-phenylethanoyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate 0
                        ethyl (4R)-4-[((2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-\{[(5-methylisoxazol-3-yl)carbonyl]amino\}-4-oxoheptanoyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate 0
                        fradafiban + 0
                        lefradafiban 0
                        levetiracetam 41
                        lilaline 0
                        melophlin P 0
                        melophlin Q 0
                        melophlin R 0
                        melophlin S 0
                        pyranonigrin I 0
                        pyranonigrin J 0
                        pyrrolidin-2-one 0
                        rolapitant 0
                        rolipram + 35
                        sch 210971 0
                        sch 210972 + 0
                        sch 213766 0
                        tenuazonic acid 0
                        trans-3-hydroxycotinine + 0
                        trans-3-hydroxycotinine beta-D-glucuronide 0
                        vibrioferrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                lactam 2855
                                                  gamma-lactam 346
                                                    pyrrolidin-2-ones 131
                                                      (-)-cotinine + 28
                                                      (1E)-2-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}prop-1-ene-1-sulfonamide 0
                                                      (2R)-N-hydroxy-2-[(3S)-3-methyl-3-\{4-[(2-methylquinolin-4-yl)methoxy]phenyl\}-2-oxopyrrolidin-1-yl]propanamide 0
                                                      (2S)-2-[(3S)-3-\{[(6-chloronaphthalen-2-yl)sulfonyl]amino\}-2-oxopyrrolidin-1-yl]-N-(1-methylethyl)-N-\{2-[(methylsulfonyl)amino]ethyl\}propanamide 0
                                                      (2S)-N-((1S,2R)-2-hydroxy-1-(4-hydroxybenzyl)-3-\{[(8S,11S)-8-[(1S)-1-methylpropyl]-7,10-dioxo-2-oxa-6,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]amino\}propyl)-3-methyl-2-(2-oxopyrrolidin-1-yl)butanamide 0
                                                      (3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide 0
                                                      (3S)-3-[(2S)-2-amino-3-hydroxybutyl]pyrrolidin-2-one 0
                                                      (3S)-3-[(2S)-2-amino-3-oxobutyl]pyrrolidin-2-one 0
                                                      (3S)-3-[(2S)-2-amino-4-hydroxy-3-oxobutyl]pyrrolidin-2-one 0
                                                      (3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide 0
                                                      (3S)-N-(3-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide 0
                                                      (3S)-N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide 0
                                                      (3Z)-ravenic acid 0
                                                      (E)-2-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}ethenesulfonamide 0
                                                      1,5,5-trimethylpyrrolidin-2-one 0
                                                      1-(4-carboxy-2-guanidinophenyl)-5,5-bis(hydroxymethyl)pyrrolidin-2-one 0
                                                      1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one 0
                                                      2-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}ethanesulfonamide 0
                                                      3-(\{[(2S)-5-oxopyrrolidin-2-yl]methyl\}sulfonyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-L-alanin[N-(1-cyanocyclopropyl)]amide 0
                                                      3-nitro-4-(2-oxopyrrolidin-1-yl)benzenesulfonamide 0
                                                      3-oxo-N-[(3S)-2-oxopyrrolidin-3-yl]dodecanamide 0
                                                      4-[(2R)-2-(aminomethyl)-2-(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(1-ethylpropyl)amino]benzoic acid 0
                                                      4-hydroxy-3-[2-oxo-3-(thieno[3,2-b]pyridine-2-sulfonylamino)pyrrolidin-1-ylmethyl]benzamidine 0
                                                      5-(5-chlorothiophen-2-yl)-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1H-1,2,4-triazole-3-sulfonamide 0
                                                      5-\{[(2-amino-9H-purin-6-yl)oxy]methyl\}pyrrolidin-2-one 0
                                                      5-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1-benzothiophene-2-sulfonamide 0
                                                      5-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1H-indole-2-sulfonamide 0
                                                      5-cyclohexylmethyl-2-Pyrrolidinone 0
                                                      5-oxoproline + 2
                                                      5-oxopyrrolidine-2-carbaldehyde 0
                                                      6-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}-1-benzothiophene-2-sulfonamide 0
                                                      6-chloro-N-\{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl\}naphthalene-2-sulfonamide 0
                                                      N-(3-acetamidopropyl)pyrrolidin-2-one 0
                                                      N-(3-furoyl)-D-valyl-L-valyl-N-((1R,2Z)-4-ethoxy-4-oxo-1-\{[(3S)-2-oxopyrrolidin-3-yl]methyl\}but-2-enyl)-D-leucinamide 0
                                                      N-Vinyl-2-pyrrolidone 30
                                                      N-[(3S,6R)-6-\{(S,E)-4-ethoxycarbonyl-1-[(S)-2-oxopyrrolidin-3-yl]but-3-en-2-ylcarbamoyl\}-2,9-dimethyl-4-oxodec-8-en-3-yl]-5-methylisoxazole-3-carboxamide 0
                                                      N-[(5-methylisoxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N(1)-((1S)-4-ethoxy-4-oxo-1-\{[(3S)-2-oxopyrrolidin-3-yl]methyl\}but-2-enyl)-L-leucinamide 0
                                                      N-[(5-methylisoxazol-3-yl)carbonyl]alanyl-L-valyl-N(1)-((1R,2Z)-4-(benzyloxy)-4-oxo-1-\{[(3R)-2-oxopyrrolidin-3-yl]methyl\}but-2-enyl)-L-leucinamide 0
                                                      N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-3-cyclohexyl-N-[(1S)-2-hydroxy-1-\{[(3S)-2-oxopyrrolidin-3-yl]methyl\}ethyl]-L-alaninamide 0
                                                      N-\{(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl\}thieno[3,2-b]pyridine-2-sulfonamide 0
                                                      N-methylpyrrolidin-2-one 0
                                                      PHA-533533 0
                                                      aniracetam 2
                                                      cotinine N-oxide 0
                                                      doxapram + 2
                                                      ethyl (2E,4S)-4-[((2R)-2-\{[N-(tert-butoxycarbonyl)-L-valyl]amino\}-2-phenylethanoyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate 0
                                                      ethyl (4R)-4-[((2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-\{[(5-methylisoxazol-3-yl)carbonyl]amino\}-4-oxoheptanoyl)amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate 0
                                                      fradafiban + 0
                                                      lefradafiban 0
                                                      levetiracetam 41
                                                      lilaline 0
                                                      melophlin P 0
                                                      melophlin Q 0
                                                      melophlin R 0
                                                      melophlin S 0
                                                      pyranonigrin I 0
                                                      pyranonigrin J 0
                                                      pyrrolidin-2-one 0
                                                      rolapitant 0
                                                      rolipram + 35
                                                      sch 210971 0
                                                      sch 210972 + 0
                                                      sch 213766 0
                                                      tenuazonic acid 0
                                                      trans-3-hydroxycotinine + 0
                                                      trans-3-hydroxycotinine beta-D-glucuronide 0
                                                      vibrioferrin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.