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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cannabinoid receptor antagonist
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Accession:CHEBI:73413 term browser browse the term
Definition:An antagonist that binds to and deactivates cannabinoid receptors.
Synonyms:related_synonym: cannabinoid receptor antagonists
 xref: Wikipedia:Cannabinoid_receptor



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AM-251 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of ABCG2 protein] CTD PMID:27423937 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:27936102 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agrp agouti related neuropeptide multiple interactions
increases expression
EXP AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AGRP mRNA]
AM 251 results in increased expression of AGRP mRNA
CTD PMID:26468265 NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of AKT1 protein]
CTD PMID:17583570 PMID:26847930 PMID:27543109 PMID:33817834 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression ISO AM 251 results in decreased expression of ARPC4 mRNA CTD PMID:16500647 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 increases expression ISO AM 251 results in increased expression of ARPP21 mRNA CTD PMID:16500647 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO AM 251 results in increased expression of ASS1 mRNA CTD PMID:16500647 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO AM 251 results in increased expression of ATF5 mRNA CTD PMID:16500647 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Avp arginine vasopressin multiple interactions
increases expression
EXP AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA]
AM 251 results in increased expression of AVP mRNA
CTD PMID:26468265 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO AM 251 results in increased expression of BCL2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
CTD PMID:26967640 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions ISO AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] CTD PMID:19022239 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO AM 251 inhibits the reaction [Morphine results in increased expression of BDNF protein] CTD PMID:27461790 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of BTG2 mRNA] CTD PMID:28095641 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases expression ISO AM 251 results in decreased expression of CAP2 mRNA CTD PMID:16500647 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373
JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of CARS1 mRNA CTD PMID:16500647 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Cartpt CART prepropeptide increases expression
multiple interactions
EXP AM 251 results in increased expression of CARTPT mRNA
[AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA
CTD PMID:26468265 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Casp1 caspase 1 multiple interactions ISO AM 251 inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]] CTD PMID:34269108 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO AM 251 results in decreased expression of CAVIN2 mRNA CTD PMID:16500647 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Ccdc86 coiled-coil domain containing 86 decreases expression ISO AM 251 results in decreased expression of CCDC86 mRNA CTD PMID:16500647 NCBI chr 1:207,590,167...207,596,547
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccnd2 cyclin D2 increases expression
multiple interactions
ISO AM 251 results in increased expression of CCND2 protein
AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]
CTD PMID:26967640 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO AM 251 results in increased expression of CD55 mRNA CTD PMID:16500647 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
ISO AM 251 results in increased expression of CDH1 protein
AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]
CTD PMID:27936102 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO AM 251 results in increased expression of CEBPG mRNA CTD PMID:16500647 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO AM 251 results in increased expression of CHRNB3 mRNA CTD PMID:16500647 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Cklf chemokine-like factor increases expression ISO AM 251 results in increased expression of CKLF mRNA CTD PMID:16500647 NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
increases methylation
ISO
EXP
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-(5-fluoropentyl)-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 1-pentyl-3-(1-naphthoyl)indole; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to CP 47497 analog; [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to HU 211; AM 251 inhibits the reaction [Dietary Fats results in increased expression of CNR1 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CNR1 mRNA]
[AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased activity of nimesulide; AM 251 binds to and results in decreased activity of CNR1 protein; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 mRNA]; AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [1-pentyfluoro-1H-indole-3-carboxylic acid 8-quinolinyl ester binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [HU 211 results in decreased expression of CNR1 protein]; AM 251 inhibits the reaction [Methylazoxymethanol Acetate results in increased expression of CNR1 mRNA]; AM 251 inhibits the reaction [N-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide binds to and results in increased activity of CNR1 protein]; AM 251 inhibits the reaction [N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide binds to and results in increased activity of CNR1 protein]
AM 251 results in decreased activity of CNR1 protein
AM 251 results in increased methylation of CNR1 promoter
AM 251 inhibits the reaction [Cannabidiol results in increased expression of CNR1 protein]
CTD PMID:12509806 PMID:17596442 PMID:20590570 PMID:21907772 PMID:24211273 More... NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:27936102 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA] CTD PMID:27936102 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of COX4I1 mRNA]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of COX4I1 mRNA] CTD PMID:26671069 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] CTD PMID:26847930 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO AM 251 inhibits the reaction [Morphine results in increased phosphorylation of CREB1 protein] CTD PMID:27461790 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
decreases expression
ISO AM 251 inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CREB3L3 protein]; AM 251 inhibits the reaction [Ethanol results in increased expression of CREB3L3 mRNA]
AM 251 results in decreased expression of CREB3L3 mRNA
CTD PMID:23894352 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases expression
EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CRH mRNA
AM 251 results in increased expression of CRH mRNA
CTD PMID:26468265 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Cs citrate synthase multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of CS mRNA] CTD PMID:26847930 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO AM 251 results in increased expression of CTH mRNA CTD PMID:16500647 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; AM 251 promotes the reaction [iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; iodopravadoline promotes the reaction [AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]] CTD PMID:17484889 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of CYP7B1 mRNA
AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7B1 mRNA]
CTD PMID:23894352 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of CYP8B1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO AM 251 results in increased expression of DDIT3 mRNA CTD PMID:16500647 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO AM 251 results in increased expression of DDIT4 mRNA CTD PMID:16500647 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO AM 251 results in decreased expression of DHX9 mRNA CTD PMID:16500647 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dld dihydrolipoamide dehydrogenase multiple interactions
increases activity
decreases expression
EXP
ISO
AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of DLD mRNA]; AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of DLD protein]
AM 251 results in increased activity of DLD protein
AM 251 results in decreased expression of DLD mRNA
AM 251 promotes the reaction [INS1 protein results in increased activity of DLD protein]
CTD PMID:26671069 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 decreases expression ISO AM 251 results in decreased expression of EFTUD2 mRNA CTD PMID:16500647 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of EGFR protein] CTD PMID:27423937 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eno3 enolase 3 multiple interactions EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of ENO3 protein] CTD PMID:26671069 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope multiple interactions ISO AM 251 affects the reaction [Dronabinol results in decreased expression of ERVFRD-1 mRNA] CTD PMID:26070387 NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO [AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] CTD PMID:27556861 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO AM 251 results in decreased expression of FEN1 mRNA CTD PMID:16500647 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in increased expression of FOS protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of FOS protein] CTD PMID:27071101 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of FOSB mRNA]
AM 251 results in increased expression of FOSB mRNA
CTD PMID:27936102 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased phosphorylation of FOXO1 protein] CTD PMID:26847930 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fra10ac1 FRA10A associated CGG repeat 1 increases expression ISO AM 251 results in increased expression of FRA10AC1 mRNA CTD PMID:16500647 NCBI chr 1:235,969,071...236,001,074
Ensembl chr 1:235,969,112...236,001,210
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in increased expression of G6PC1 protein] CTD PMID:26847930 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Glo1 glyoxalase 1 decreases expression
multiple interactions
EXP AM 251 results in decreased expression of GLO1 protein
AM 251 inhibits the reaction [Dietary Carbohydrates results in decreased expression of GLO1 protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of GLO1 protein]
CTD PMID:26671069 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpi glucose-6-phosphate isomerase multiple interactions
decreases expression
EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of GPI protein]
AM 251 results in decreased expression of GPI protein
CTD PMID:26671069 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpr55 G protein-coupled receptor 55 multiple interactions
increases activity
ISO 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased activity of GPR55 protein]; 4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased activity of GPR55 protein] CTD PMID:27423937 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO AM 251 results in increased expression of GPX1 mRNA CTD PMID:16500647 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO AM 251 promotes the reaction [INS1 protein results in increased activity of GSR protein] CTD PMID:26671069 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gtf3c5 general transcription factor IIIC subunit 5 decreases expression ISO AM 251 results in decreased expression of GTF3C5 mRNA CTD PMID:16500647 NCBI chr 3:11,893,867...11,914,187
Ensembl chr 3:11,893,875...11,914,180
JBrowse link
G Hax1 HCLS1 associated protein X-1 increases expression ISO AM 251 results in increased expression of HAX1 mRNA CTD PMID:16500647 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions EXP
ISO
AM 251 inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of HCRT mRNA]
AM 251 inhibits the reaction [Dietary Fats results in increased expression of HCRT protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC mRNA]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of HCRT protein modified form]
CTD PMID:26468265 PMID:27071101 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 increases expression ISO AM 251 results in increased expression of H2AC6 mRNA CTD PMID:16500647 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO AM 251 results in increased expression of HMOX1 mRNA CTD PMID:16500647 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnmt histamine N-methyltransferase increases expression ISO AM 251 results in increased expression of HNMT mRNA CTD PMID:16500647 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO AM 251 results in decreased expression of HSPA1B mRNA CTD PMID:16500647 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO AM 251 results in decreased expression of HSPA8 mRNA CTD PMID:16500647 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA] CTD PMID:22198381 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [AM 251 co-treated with iodopravadoline] promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; [AM 251 co-treated with iodopravadoline] promotes the reaction [methanandamide promotes the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]] CTD PMID:27556861 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il33 interleukin 33 multiple interactions EXP AM 251 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]] CTD PMID:31732924 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 increases expression ISO AM 251 results in increased expression of IMMP2L mRNA CTD PMID:16500647 NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840
JBrowse link
G Ins1 insulin 1 multiple interactions ISO AM 251 inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; AM 251 promotes the reaction [INS1 protein results in increased activity of DLD protein]; AM 251 promotes the reaction [INS1 protein results in increased activity of GSR protein] CTD PMID:26671069 PMID:26967640 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like increases expression ISO AM 251 results in increased expression of IRF2BPL mRNA CTD PMID:16500647 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased phosphorylation of IRS2 protein] CTD PMID:26847930 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA] CTD PMID:27936102 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP AM 251 inhibits the reaction [Dietary Carbohydrates results in increased expression of LDHA protein] CTD PMID:26671069 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lep leptin multiple interactions ISO AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased secretion of POMC protein modified form]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of FOS protein]; AM 251 inhibits the reaction [LEP gene mutant form results in increased expression of HCRT protein modified form] CTD PMID:27071101 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lmnb2 lamin B2 decreases expression ISO AM 251 results in decreased expression of LMNB2 mRNA CTD PMID:16500647 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases expression ISO AM 251 results in decreased expression of MAP2K3 mRNA CTD PMID:16500647 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein]
AM 251 results in increased phosphorylation of MAPK1 protein
AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK1 protein]; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK1 protein]
CTD PMID:17583570 PMID:17596442 PMID:18159069 PMID:19477951 PMID:27071101 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; AM 251 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein]
AM 251 results in increased phosphorylation of MAPK3 protein
AM 251 inhibits the reaction [[3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [[JZL 184 co-treated with Glutamic Acid] results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of MAPK3 protein]; AM 251 inhibits the reaction [Morphine results in increased phosphorylation of MAPK3 protein]
CTD PMID:17583570 PMID:17596442 PMID:18159069 PMID:19477951 PMID:27071101 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO AM 251 results in decreased expression of MCM3 mRNA CTD PMID:16500647 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO AM 251 results in decreased expression of MCM5 mRNA CTD PMID:16500647 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO AM 251 results in decreased expression of MFN2 mRNA CTD PMID:16500647 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA]
AM 251 results in increased expression of MMP2 protein
CTD PMID:27936102 PMID:29883990 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 decreases expression ISO AM 251 results in decreased expression of NCAPD3 mRNA CTD PMID:16500647 NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 increases expression ISO AM 251 results in increased expression of NCOA7 mRNA CTD PMID:16500647 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
JBrowse link
G Npy neuropeptide Y multiple interactions EXP [AM 251 co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of NPY mRNA CTD PMID:26468265 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 mRNA]; AM 251 inhibits the reaction [Dronabinol results in decreased expression of OPRL1 protein] CTD PMID:21603976 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions
increases expression
increases secretion
EXP AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA]
AM 251 results in increased expression of OXT mRNA
AM 251 results in increased secretion of OXT protein
CTD PMID:26468265 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Papola poly (A) polymerase alpha decreases expression ISO AM 251 results in decreased expression of PAPOLA mRNA CTD PMID:16500647 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein] CTD PMID:19509271 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in increased expression of PCK1 mRNA]; AM 251 inhibits the reaction [Dietary Fats results in increased expression of PCK1 protein] CTD PMID:26847930 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO AM 251 results in increased expression of PEA15 mRNA CTD PMID:16500647 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases expression
EXP
ISO
AM 251 promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA]
AM 251 results in increased expression of POMC mRNA
AM 251 inhibits the reaction [Dietary Fats results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [Dietary Fats results in decreased expression of POMC protein]; AM 251 inhibits the reaction [Dietary Fats results in decreased secretion of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC mRNA]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein modified form]; AM 251 inhibits the reaction [HCRT protein modified form results in increased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC mRNA]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased expression of POMC protein]; AM 251 inhibits the reaction [LEP gene mutant form results in decreased secretion of POMC protein modified form]
CTD PMID:26468265 PMID:27071101 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppif peptidylprolyl isomerase F decreases expression ISO AM 251 results in decreased expression of PPIF mRNA CTD PMID:16500647 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 decreases expression ISO AM 251 results in decreased expression of PTBP1 mRNA CTD PMID:16500647 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [AM 251 co-treated with iodopravadoline] inhibits the reaction [Dronabinol results in increased phosphorylation of PTK2 protein] CTD PMID:31461164 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO AM 251 results in decreased expression of RACGAP1 mRNA CTD PMID:16500647 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad54l RAD54 like decreases expression ISO AM 251 results in decreased expression of RAD54L mRNA CTD PMID:16500647 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rcc1 regulator of chromosome condensation 1 decreases expression ISO AM 251 results in decreased expression of RCC1 mRNA CTD PMID:16500647 NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
JBrowse link
G Rcc1l RCC1 like decreases expression ISO AM 251 results in decreased expression of RCC1L mRNA CTD PMID:16500647 NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO AM 251 results in decreased expression of RFC5 mRNA CTD PMID:16500647 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rnaseh1 ribonuclease H1 increases expression ISO AM 251 results in increased expression of RNASEH1 mRNA CTD PMID:16500647 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236
JBrowse link
G Rpa1 replication protein A1 decreases expression ISO AM 251 results in decreased expression of RPA1 mRNA CTD PMID:16500647 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rwdd1 RWD domain containing 1 increases expression ISO AM 251 results in increased expression of RWDD1 mRNA CTD PMID:16500647 NCBI chr20:25,949,723...25,967,147
Ensembl chr20:25,941,966...25,967,193
JBrowse link
G S100a2 S100 calcium binding protein A2 increases expression ISO AM 251 results in increased expression of S100A2 mRNA CTD PMID:16500647 NCBI chr 2:176,077,081...176,078,325 JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of SARS1 mRNA CTD PMID:16500647 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sesn2 sestrin 2 increases expression ISO AM 251 results in increased expression of SESN2 mRNA CTD PMID:16500647 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Slc18b1 solute carrier family 18 member B1 decreases expression ISO AM 251 results in decreased expression of SLC18B1 mRNA CTD PMID:16500647 NCBI chr 1:21,628,235...21,670,807
Ensembl chr 1:21,628,237...21,670,684
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO AM 251 results in increased expression of SLC1A4 mRNA CTD PMID:16500647 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO AM 251 results in increased expression of SLC30A1 mRNA CTD PMID:16500647 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc46a1 solute carrier family 46 member 1 increases expression ISO AM 251 results in increased expression of SLC46A1 mRNA CTD PMID:19145103 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions EXP AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of SLC6A3 mRNA] CTD PMID:29113897 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO AM 251 results in increased expression of SLC7A5 mRNA CTD PMID:16500647 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:27936102 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of SNAI1 mRNA
AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]
CTD PMID:27936102 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA] CTD PMID:27936102 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 decreases expression ISO AM 251 results in decreased expression of SPTBN1 mRNA CTD PMID:16500647 NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO AM 251 results in decreased expression of SRSF1 mRNA CTD PMID:16500647 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Stam signal transducing adaptor molecule decreases expression ISO AM 251 results in decreased expression of STAM mRNA CTD PMID:16500647 NCBI chr17:77,120,235...77,166,173
Ensembl chr17:77,120,158...77,166,467
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
multiple interactions
ISO AM 251 results in decreased expression of STAT3 mRNA
AM 251 inhibits the reaction [HCRT protein modified form results in increased phosphorylation of and results in increased activity of STAT3 protein]
AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of STAT3 protein]
CTD PMID:16500647 PMID:27071101 PMID:33817834 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Sugp2 SURP and G patch domain containing 2 decreases expression ISO AM 251 results in decreased expression of SUGP2 mRNA CTD PMID:16500647 NCBI chr16:19,159,951...19,191,412
Ensembl chr16:19,164,767...19,191,340
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO AM 251 results in decreased expression of SUN1 mRNA CTD PMID:16500647 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 decreases expression ISO AM 251 results in decreased expression of TACC3 mRNA CTD PMID:16500647 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked increases expression ISO AM 251 results in increased expression of TBL1X mRNA CTD PMID:16500647 NCBI chr  X:41,574,558...41,731,117
Ensembl chr  X:41,576,047...41,731,101
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO AM 251 inhibits the reaction [Dietary Fats results in decreased expression of TFAM mRNA] CTD PMID:26847930 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of FOSB mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of JUNB mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB2 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB3 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFBR1 mRNA]; AM 251 inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:27936102 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB2 mRNA] CTD PMID:27936102 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFB3 mRNA] CTD PMID:27936102 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions ISO AM 251 inhibits the reaction [TGFB1 protein results in increased expression of TGFBR1 mRNA] CTD PMID:27936102 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP AM 251 affects the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of TH mRNA] CTD PMID:29113897 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; [iodopravadoline co-treated with AM 251] inhibits the reaction [methanandamide results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein]; AM 251 inhibits the reaction [methanandamide results in increased expression of TIMP1 protein] CTD PMID:18159069 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tmem126a transmembrane protein 126A increases expression ISO AM 251 results in increased expression of TMEM126A mRNA CTD PMID:16500647 NCBI chr 1:144,424,481...144,430,730
Ensembl chr 1:144,422,703...144,430,628
JBrowse link
G Tnf tumor necrosis factor decreases response to substance ISO AM 251 results in decreased susceptibility to TNF protein CTD PMID:20626112 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO AM 251 results in increased expression of TRIB3 mRNA CTD PMID:16500647 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Tspan10 tetraspanin 10 increases expression ISO AM 251 results in increased expression of TSPAN10 mRNA CTD PMID:16500647 NCBI chr10:105,715,803...105,721,503
Ensembl chr10:105,715,961...105,719,813
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO AM 251 results in increased expression of TXNIP mRNA CTD PMID:16500647 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO AM 251 results in decreased expression of UGCG mRNA CTD PMID:16500647 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO AM 251 results in decreased expression of UHRF1 mRNA CTD PMID:16500647 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein]] CTD PMID:26467187 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]] CTD PMID:26467187 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO AM 251 results in increased expression of VLDLR mRNA CTD PMID:16500647 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of WARS1 mRNA CTD PMID:16500647 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO AM 251 results in increased expression of XBP1 mRNA CTD PMID:16500647 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 increases expression ISO AM 251 results in increased expression of YARS1 mRNA CTD PMID:16500647 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
G Yy1 YY1 transcription factor multiple interactions ISO AM 251 inhibits the reaction [Ethanol results in increased expression of YY1 mRNA] CTD PMID:28095641 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfp142 zinc finger protein 142 decreases expression ISO AM 251 results in decreased expression of ZNF142 mRNA CTD PMID:16500647 NCBI chr 9:76,141,053...76,164,784
Ensembl chr 9:76,142,227...76,164,856
JBrowse link
G Zmym6 zinc finger MYM-type containing 6 increases expression ISO AM 251 results in increased expression of ZMYM6 mRNA CTD PMID:16500647 NCBI chr 5:139,396,374...139,444,357
Ensembl chr 5:139,396,727...139,444,279
JBrowse link
AM6545 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein] CTD PMID:30184259 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Alb albumin multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in increased expression of ALB protein] CTD PMID:30184259 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Arg1 arginase 1 multiple interactions ISO AM6545 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone affects the expression of ARG1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]; Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]] CTD PMID:30184259 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein] CTD PMID:30184259 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]] CTD PMID:30184259 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA] CTD PMID:30184259 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd163 CD163 molecule multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]] CTD PMID:30184259 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]] CTD PMID:30184259 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein] CTD PMID:30184259 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]] CTD PMID:30184259 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]] CTD PMID:30184259 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]] CTD PMID:30184259 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]] CTD PMID:30184259 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]] CTD PMID:30184259 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
CB1 receptor antagonist term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 decreases response to substance EXP CB1 receptor antagonist decreases response to substance HU210 in ventral tegmental area RGD PMID:21187978 RGD:596933102 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
rimonabant term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha affects expression ISO Rimonabant affects the expression of ACACA mRNA CTD PMID:20110567 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression ISO Rimonabant results in increased expression of ACACB mRNA CTD PMID:20110567 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain affects expression
multiple interactions
ISO Rimonabant affects the expression of ACADM mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACADM mRNA]
CTD PMID:19030233 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acbd5 acyl-CoA binding domain containing 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACBD5 mRNA] CTD PMID:19030233 NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression EXP Rimonabant results in decreased expression of ACTA2 mRNA CTD PMID:21863215 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actr2 actin related protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACTR2 mRNA] CTD PMID:19030233 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ADAMTS1 mRNA] CTD PMID:19030233 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression EXP Rimonabant results in decreased expression of ADGRE1 mRNA CTD PMID:30365523 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Rimonabant results in increased expression of ADIPOQ mRNA; Rimonabant results in increased expression of ADIPOQ protein CTD PMID:16282221 PMID:20110567 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 multiple interactions
increases expression
ISO Rimonabant inhibits the reaction [MIR762 mRNA results in decreased expression of AGAP2 mRNA]; Rimonabant promotes the reaction [Dietary Fats results in increased expression of AGAP2 mRNA]
Rimonabant results in increased expression of AGAP2 mRNA
CTD PMID:30910812 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of AKT1 protein]
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of AKT1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of AKT1 protein]
CTD PMID:12834810 PMID:31917333 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ALKBH1 mRNA] CTD PMID:19030233 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Anxa1 annexin A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA] CTD PMID:19030233 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa2 annexin A2 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA2 mRNA]
Rimonabant affects the expression of ANXA2 mRNA
CTD PMID:19030233 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apob apolipoprotein B increases secretion ISO Rimonabant results in increased secretion of APOB protein CTD PMID:20110567 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G App amyloid beta precursor protein affects expression
multiple interactions
ISO Rimonabant affects the expression of APP mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of APP mRNA]
CTD PMID:19030233 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arg1 arginase 1 multiple interactions ISO Rimonabant promotes the reaction [Dietary Fats results in increased expression of ARG1] CTD PMID:30910812 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 affects expression
multiple interactions
ISO Rimonabant affects the expression of ARHGEF12 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARHGEF12 mRNA]
CTD PMID:19030233 NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARPP19 mRNA] CTD PMID:19030233 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]] CTD PMID:27779402 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF4 mRNA] CTD PMID:31054322 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF6 mRNA] CTD PMID:31054322 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ATP5ME mRNA] CTD PMID:19030233 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atrnl1 attractin like 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA] CTD PMID:19030233 NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Rimonabant results in decreased expression of AURKB protein CTD PMID:19479993 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of BAX protein]]
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of BAX protein]
CTD PMID:27932991 PMID:30769029 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in decreased expression of BCL2 protein]]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein] CTD PMID:26967640 PMID:30769029 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA] CTD PMID:20929960 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BRAF mRNA] CTD PMID:19030233 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BZW1 mRNA] CTD PMID:19030233 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of C1GALT1 mRNA] CTD PMID:19030233 NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831
JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAB39L mRNA] CTD PMID:19030233 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
JBrowse link
G Calm1 calmodulin 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CALM1 mRNA]
Rimonabant affects the expression of CALM1 mRNA
CTD PMID:19030233 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Canx calnexin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CANX mRNA] CTD PMID:19030233 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Capn7 calpain 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAPN7 mRNA] CTD PMID:19030233 NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905
JBrowse link
G Cartpt CART prepropeptide multiple interactions
increases response to substance
affects expression
ISO FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]
CARTPT results in increased susceptibility to Rimonabant
CTD PMID:16131814 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of CASP1 protein] CTD PMID:27932991 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CASP12 mRNA] CTD PMID:19030233 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Rimonabant inhibits the reaction [XLR-11 results in increased activity of CASP3 protein]
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased cleavage of CASP3 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]
CTD PMID:26209559 PMID:29410032 PMID:30769029 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cav1 caveolin 1 affects expression
multiple interactions
ISO Rimonabant affects the expression of CAV1 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV1 mRNA]
CTD PMID:19030233 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cav2 caveolin 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV2 mRNA] CTD PMID:19030233 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cavin1 caveolae associated protein 1 affects expression ISO Rimonabant affects the expression of CAVIN1 mRNA CTD PMID:19030233 NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCAR1 mRNA] CTD PMID:19030233 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2]
Rimonabant results in decreased expression of CCL2 mRNA
CTD PMID:30365523 PMID:32832534 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL3] CTD PMID:32832534 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Rimonabant results in increased expression of CCNB1 protein CTD PMID:19479993 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Rimonabant results in decreased expression of CCND1 protein CTD PMID:16822929 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein] CTD PMID:26967640 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCNG1 mRNA] CTD PMID:19030233 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccpg1 cell cycle progression 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCPG1 mRNA] CTD PMID:19030233 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Rimonabant co-treated with MIR762 mRNA] affects the expression of CCR7 mRNA CTD PMID:30910812 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd36 CD36 molecule affects expression
multiple interactions
ISO Rimonabant affects the expression of CD36 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA]
CTD PMID:19030233 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cdc73 cell division cycle 73 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDC73 mRNA] CTD PMID:19030233 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Cdk5 cyclin-dependent kinase 5 multiple interactions ISO Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; Rimonabant inhibits the reaction [Ethanol results in increased activity of CDK5 protein] CTD PMID:30143782 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein] CTD PMID:30143782 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdkl2 cyclin dependent kinase like 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDKL2 mRNA] CTD PMID:19030233 NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Rimonabant results in increased expression of CDKN1B protein CTD PMID:16822929 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA] CTD PMID:27659731 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of CEBPD mRNA] CTD PMID:19030233 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Chd9 chromodomain helicase DNA binding protein 9 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CHD9 mRNA] CTD PMID:19030233 NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
JBrowse link
G Chek1 checkpoint kinase 1 decreases phosphorylation ISO Rimonabant results in decreased phosphorylation of CHEK1 protein CTD PMID:19479993 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Clic4 chloride intracellular channel 4 affects expression
multiple interactions
ISO Rimonabant affects the expression of CLIC4 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLIC4 mRNA]
CTD PMID:19030233 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Cltc clathrin heavy chain multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLTC mRNA] CTD PMID:19030233 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cnot1 CCR4-NOT transcription complex, subunit 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CNOT1 mRNA] CTD PMID:19030233 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNP protein] CTD PMID:32956517 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
affects localization
affects binding
decreases expression
ISO
EXP
1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea analog inhibits the reaction [Rimonabant binds to CNR1 protein]; 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea inhibits the reaction [Rimonabant binds to CNR1 protein]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Rimonabant binds to CNR1 protein]; 5F-CUMYL-PICA inhibits the reaction [Rimonabant binds to CNR1 protein]; AM 6527 inhibits the reaction [Rimonabant binds to CNR1 protein]; arachidonyl dopamine inhibits the reaction [Rimonabant binds to CNR1 protein]; Dronabinol inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate inhibits the reaction [Rimonabant binds to CNR1 protein]; N'-((3Z)-1-(1-hexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide affects the reaction [Rimonabant binds to CNR1 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [HU 211 results in increased activity of CNR1]
Rimonabant results in decreased activity of CNR1 protein
Rimonabant affects the localization of CNR1 protein
Rimonabant results in decreased expression of CNR1 mRNA
[Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog; Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole analog binds to CNR1 protein]; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole binds to CNR1 protein]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in decreased abundance of Nitric Oxide]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of CNR1 protein]
6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole inhibits the reaction [Rimonabant binds to CNR1 protein]; [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Nicotine; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [5F-ADB cannabinoid binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [5F-ADB cannabinoid metabolite binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [HU 211 binds to and results in increased activity of CNR1 protein]
CTD PMID:10027878 PMID:10422789 PMID:10871313 PMID:11517236 PMID:11558437 More... NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR2 protein] CTD PMID:27779402 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Rimonabant results in decreased expression of COL1A1 mRNA CTD PMID:21863215 PMID:30365523 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of COPG2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of COPG2 mRNA]
CTD PMID:19030233 NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Rimonabant results in increased expression of CPT1A mRNA CTD PMID:30365523 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of CREB1 protein]
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of and results in decreased phosphorylation of CREB1 protein]
CTD PMID:15913574 PMID:19912468 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CREB3L2 mRNA] CTD PMID:19030233 NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
JBrowse link
G Crh corticotropin releasing hormone decreases expression
multiple interactions
EXP Rimonabant results in decreased expression of CRH mRNA
Dronabinol affects the reaction [Rimonabant results in decreased expression of CRH mRNA]; Rimonabant inhibits the reaction [HU 211 results in decreased expression of CRH mRNA]
CTD PMID:12968131 PMID:15099659 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Csde1 cold shock domain containing E1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CSDE1 mRNA] CTD PMID:19030233 NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784
JBrowse link
G Cul1 cullin 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL1 mRNA] CTD PMID:19030233 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cul3 cullin 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL3 mRNA] CTD PMID:19030233 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CXADR mRNA] CTD PMID:19030233 NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL10] CTD PMID:32832534 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL1] CTD PMID:32832534 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CYP4V3 mRNA] CTD PMID:19030233 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of DDIT3 mRNA] CTD PMID:31054322 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx27 DEAD-box helicase 27 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of DDX27 mRNA] CTD PMID:19030233 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DDX3X mRNA] CTD PMID:19030233 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DNAJC10 mRNA] CTD PMID:19030233 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DPP4 mRNA] CTD PMID:19030233 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dr1 down-regulator of transcription 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DR1 mRNA] CTD PMID:19030233 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DYNC1I2 mRNA] CTD PMID:19030233 NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EDEM1 mRNA] CTD PMID:19030233 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Efna5 ephrin A5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EFNA5 mRNA] CTD PMID:19030233 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 multiple interactions ISO Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]] CTD PMID:30143782 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF4G2 mRNA] CTD PMID:19030233 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF5 mRNA] CTD PMID:19030233 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ELL2 mRNA] CTD PMID:19030233 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EPS15 mRNA] CTD PMID:19030233 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ERMP1 mRNA] CTD PMID:19030233 NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions EXP
ISO
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of FAAH mRNA
FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide]
CTD PMID:16131814 PMID:27385208 PMID:32833042 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fam199x family with sequence similarity 199, X-linked multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAM199X mRNA] CTD PMID:19030233 NCBI chr  X:100,384,230...100,419,935
Ensembl chr  X:100,384,225...100,414,938
JBrowse link
G Far1 fatty acyl CoA reductase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAR1 mRNA] CTD PMID:19030233 NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of FASN mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]
CTD PMID:19030233 PMID:20110567 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FBXL5 mRNA] CTD PMID:19030233 NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FBXW7 mRNA] CTD PMID:19030233 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fem1a fem-1 homolog A multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FEM1A mRNA] CTD PMID:19030233 NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628
JBrowse link
G Fermt2 FERM domain containing kindlin 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FERMT2 mRNA] CTD PMID:19030233 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FGF1 mRNA]
Rimonabant affects the expression of FGF1 mRNA
CTD PMID:19030233 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA] CTD PMID:19030233 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fndc3b fibronectin type III domain containing 3B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FNDC3B mRNA] CTD PMID:19030233 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOS protein]
[Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein]
CTD PMID:9751146 PMID:12560108 PMID:15280883 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSB protein] CTD PMID:9751146 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL1 protein] CTD PMID:9751146 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL2 protein] CTD PMID:9751146 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Frmd4b FERM domain containing 4B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FRMD4B mRNA] CTD PMID:19030233 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 increases expression ISO Rimonabant results in increased expression of G6PC3 mRNA CTD PMID:20110567 NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Rimonabant results in increased expression of GAPDH mRNA CTD PMID:16282221 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of GFAP protein
Rimonabant inhibits the reaction [Dronabinol results in increased expression of GFAP mRNA]
CTD PMID:21373835 PMID:36529297 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GGPS1 mRNA] CTD PMID:19030233 NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
JBrowse link
G Gls glutaminase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GLS mRNA] CTD PMID:19030233 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gmfb glia maturation factor, beta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GMFB mRNA] CTD PMID:19030233 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression ISO Rimonabant results in decreased expression of GPLD1 mRNA CTD PMID:20110567 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gpr55 G protein-coupled receptor 55 multiple interactions ISO Rimonabant binds to and results in increased activity of GPR55 protein CTD PMID:17876302 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Gpt glutamic--pyruvic transaminase decreases expression EXP
ISO
Rimonabant results in decreased expression of GPT protein CTD PMID:28705172 PMID:30365523 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression
multiple interactions
ISO Rimonabant affects the expression of GRB14 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GRB14 mRNA]
CTD PMID:19030233 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1]
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1 mRNA]
CTD PMID:19912468 PMID:29230395 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2A] CTD PMID:19912468 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2B] CTD PMID:19912468 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP Rimonabant results in increased expression of GSTA1 mRNA CTD PMID:30365523 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hdhd2 haloacid dehalogenase-like hydrolase domain containing 2 affects expression ISO Rimonabant affects the expression of HDHD2 mRNA CTD PMID:19030233 NCBI chr18:70,488,315...70,526,471
Ensembl chr18:70,474,926...70,526,470
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA] CTD PMID:19030233 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIPK3 mRNA] CTD PMID:19030233 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Rimonabant results in increased expression of HMOX1 mRNA; Rimonabant results in increased expression of HMOX1 protein CTD PMID:30365523 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases activity ISO Rimonabant results in decreased activity of HNF4A protein CTD PMID:31981244 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HSP90AA1 mRNA] CTD PMID:19030233 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of HSPA5 mRNA] CTD PMID:31054322 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hycc2 hyccin PI4KA lipid kinase complex subunit 2 affects expression ISO Rimonabant affects the expression of HYCC2 mRNA CTD PMID:19030233 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of ICAM1 protein
Rimonabant inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
CTD PMID:21373835 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions EXP Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]; Rimonabant inhibits the reaction [Cannabinol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]] CTD PMID:11520904 PMID:11727767 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGF1 mRNA] CTD PMID:19030233 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 affects expression
multiple interactions
ISO Rimonabant affects the expression of IGFBP5 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGFBP5 mRNA]
CTD PMID:19030233 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein]] CTD PMID:32385136 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in decreased expression of IL12RB2 mRNA] CTD PMID:14741435 PMID:18792785 NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] CTD PMID:27932991 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL1B]; Rimonabant inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:15748152 PMID:32832534 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL6] CTD PMID:32832534 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of INS1 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein]
Rimonabant results in decreased expression of INS1 protein
CTD PMID:19030233 PMID:26563389 PMID:26967640 PMID:30910812 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ins2 insulin 2 decreases expression ISO Rimonabant results in decreased expression of INS protein CTD PMID:20110567 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IQGAP1 mRNA]
Rimonabant affects the expression of IQGAP1 mRNA
CTD PMID:19030233 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Irf5 interferon regulatory factor 5 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IRF5] CTD PMID:32832534 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
JBrowse link
G Itgam integrin subunit alpha M decreases expression EXP Rimonabant results in decreased expression of ITGAM mRNA CTD PMID:30365523 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGAV mRNA] CTD PMID:19030233 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGB1 mRNA] CTD PMID:19030233 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITPR2 mRNA] CTD PMID:19030233 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Ivns1abp influenza virus NS1A binding protein multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA] CTD PMID:19030233 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Kif5b kinesin family member 5B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KIF5B mRNA] CTD PMID:19030233 NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
G Klf4 KLF transcription factor 4 increases expression
multiple interactions
ISO Rimonabant results in increased expression of KLF4 mRNA
MIR466J mRNA affects the reaction [Rimonabant results in increased expression of KLF4 mRNA]; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of KLF4 mRNA]
CTD PMID:30910812 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLF6 mRNA] CTD PMID:19030233 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klhl9 kelch-like family member 9 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLHL9 mRNA] CTD PMID:19030233 NCBI chr 5:103,333,747...103,337,931 JBrowse link
G Kpna3 karyopherin subunit alpha 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNA3 mRNA] CTD PMID:19030233 NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNB1 mRNA] CTD PMID:19030233 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LAMP2 mRNA] CTD PMID:19030233 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LARGE1 mRNA]
Rimonabant affects the expression of LARGE1 mRNA
CTD PMID:19030233 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
JBrowse link
G Lep leptin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of LEP protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein] CTD PMID:19030233 PMID:26967640 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Rimonabant inhibits the reaction [Dronabinol results in decreased expression of LHB protein] CTD PMID:9825732 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lipc lipase C, hepatic type increases expression ISO Rimonabant results in increased expression of LIPC mRNA CTD PMID:20110567 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipe lipase E, hormone sensitive type affects expression ISO Rimonabant affects the expression of LIPE mRNA CTD PMID:20110567 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Lmo1 LIM domain only 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LMO1 mRNA] CTD PMID:19030233 NCBI chr 1:163,132,338...163,168,521
Ensembl chr 1:163,132,339...163,168,522
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 affects expression ISO Rimonabant affects the expression of LPGAT1 mRNA CTD PMID:19030233 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LRRFIP1 mRNA] CTD PMID:19030233 NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
JBrowse link
G Mag myelin-associated glycoprotein multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of MAG protein] CTD PMID:32956517 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Rimonabant results in increased expression of and results in increased lipidation of MAP1LC3B protein CTD PMID:31570772 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
affects localization
decreases activity
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein]
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Rimonabant affects the localization of MAPK1 protein
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK1 protein]
Rimonabant results in decreased activity of MAPK1 protein
CTD PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases activity
affects localization
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK3 protein]
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Rimonabant results in decreased activity of MAPK3 protein
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein]
Rimonabant affects the localization of MAPK3 protein
CTD PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein] CTD PMID:18950629 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MARCHF6 mRNA] CTD PMID:19030233 NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL1 mRNA] CTD PMID:19030233 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL2 mRNA] CTD PMID:19030233 NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mbp myelin basic protein multiple interactions EXP Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MBP protein] CTD PMID:17880390 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of MEF2C mRNA] CTD PMID:36529297 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mest mesoderm specific transcript affects expression
multiple interactions
ISO Rimonabant affects the expression of MEST mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MEST mRNA]
CTD PMID:19030233 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to Rimonabant CTD PMID:21911610 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mir16 microRNA 16 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of MIR16 mRNA] CTD PMID:19030233 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions ISO Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein] CTD PMID:31220554 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression EXP Rimonabant results in decreased expression of MMP13 mRNA CTD PMID:21863215 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mog myelin oligodendrocyte glycoprotein multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased expression of MOG protein] CTD PMID:32956517 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Mospd1 motile sperm domain containing 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MOSPD1 mRNA] CTD PMID:19030233 NCBI chr  X:133,100,200...133,127,960
Ensembl chr  X:133,100,422...133,127,908
Ensembl chr 1:133,100,422...133,127,908
Ensembl chr14:133,100,422...133,127,908
JBrowse link
G Mycbp2 MYC binding protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MYCBP2 mRNA] CTD PMID:19030233 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NAP1L1 mRNA] CTD PMID:19030233 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions EXP [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of NAPEPLD mRNA CTD PMID:32833042 NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
JBrowse link
G Ncl nucleolin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NCL mRNA] CTD PMID:19030233 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ndc1 NDC1 transmembrane nucleoporin affects expression ISO Rimonabant affects the expression of NDC1 mRNA CTD PMID:19030233 NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB11 mRNA] CTD PMID:19030233 NCBI chr  X:1,572,805...1,575,063
Ensembl chr  X:1,572,785...1,575,062
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB9 mRNA]
Rimonabant affects the expression of NDUFB9 mRNA
CTD PMID:19030233 NCBI chr 7:90,480,948...90,487,367
Ensembl chr 7:90,436,621...90,488,009
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFS8 mRNA] CTD PMID:19030233 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEDD4 mRNA] CTD PMID:19030233 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nek7 NIMA-related kinase 7 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEK7 mRNA]
Rimonabant affects the expression of NEK7 mRNA
CTD PMID:19030233 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Nes nestin multiple interactions ISO [Rimonabant co-treated with Dronabinol] results in increased expression of NES mRNA CTD PMID:36529297 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NFATC3 mRNA] CTD PMID:19030233 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP Rimonabant results in increased expression of NFE2L2 mRNA CTD PMID:30365523 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nid1 nidogen 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NID1 mRNA]
Rimonabant affects the expression of NID1 mRNA
CTD PMID:19030233 NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of NLRP3]
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of NLRP3 protein]
CTD PMID:27932991 PMID:32832534 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NOS2]; Rimonabant promotes the reaction [PF 3845 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]
CTD PMID:11520904 PMID:15748152 PMID:30910812 PMID:31121907 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NPR3 mRNA]
Rimonabant affects the expression of NPR3 mRNA
CTD PMID:19030233 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Rimonabant results in increased expression of NQO1 mRNA; Rimonabant results in increased expression of NQO1 protein CTD PMID:30365523 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NR3C1 mRNA] CTD PMID:19030233 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Ntn1 netrin 1 multiple interactions
decreases expression
ISO Rimonabant affects the reaction [Dietary Fats affects the expression of NTN1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NTN1 mRNA]; Rimonabant inhibits the reaction [MIR762 mRNA results in increased expression of NTN1 mRNA]
Rimonabant results in decreased expression of NTN1 mRNA
CTD PMID:30910812 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OPA1 mRNA] CTD PMID:19030233 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 affects expression
multiple interactions
ISO Rimonabant affects the expression of OSBPL8 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OSBPL8 mRNA]
CTD PMID:19030233 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
JBrowse link
G Pakap paralemmin A kinase anchor protein multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PAKAP mRNA]
Rimonabant affects the expression of PAKAP mRNA
CTD PMID:19030233 NCBI chr 5:72,536,986...72,648,524
NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Rimonabant results in decreased expression of PARP1 protein CTD PMID:19479993 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PCX mRNA] CTD PMID:19030233 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO Rimonabant results in increased expression of PCK1 mRNA CTD PMID:20110567 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcyox1 prenylcysteine oxidase 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PCYOX1 mRNA]
Rimonabant affects the expression of PCYOX1 mRNA
CTD PMID:19030233 NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
JBrowse link
G Phip pleckstrin homology domain interacting protein multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PHIP mRNA] CTD PMID:19030233 NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha affects expression
multiple interactions
ISO Rimonabant affects the expression of PIK3CA mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PIK3CA mRNA]
CTD PMID:19030233 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Plac8 placenta associated 8 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PLAC8 mRNA] CTD PMID:19030233 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PLEKHA1 mRNA] CTD PMID:19030233 NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
JBrowse link
G Plin2 perilipin 2 decreases expression
multiple interactions
ISO Rimonabant results in decreased expression of PLIN2 protein
Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein]
CTD PMID:31570772 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Pmm1 phosphomannomutase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PMM1 mRNA] CTD PMID:19030233 NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLD2 mRNA] CTD PMID:19030233 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
JBrowse link
G Polr2j RNA polymerase II subunit J multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLR2J mRNA] CTD PMID:19030233 NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP Rimonabant results in increased expression of PPARA mRNA CTD PMID:30365523 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Rimonabant affects the expression of PPARG mRNA CTD PMID:20110567 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppfibp1 PPFIA binding protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPFIBP1 mRNA] CTD PMID:19030233 NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP1CB mRNA] CTD PMID:19030233 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP3CA mRNA] CTD PMID:19030233 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prkd3 protein kinase D3 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRKD3 mRNA]
Rimonabant affects the expression of PRKD3 mRNA
CTD PMID:19030233 NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases response to substance
multiple interactions
ISO
EXP
PRKN results in decreased susceptibility to Rimonabant
Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]
CTD PMID:15882845 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Prl prolactin multiple interactions
increases expression
ISO
EXP
Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]]
Dronabinol affects the reaction [Rimonabant results in increased expression of PRL protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased expression of PRL protein]
CTD PMID:9825732 PMID:15099659 PMID:31154070 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPF40A mRNA] CTD PMID:19030233 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 affects expression
multiple interactions
ISO Rimonabant affects the expression of PRPS1 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPS1 mRNA]
CTD PMID:19030233 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187
JBrowse link
G Ptbp3 polypyrimidine tract binding protein 3 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTBP3 mRNA] CTD PMID:19030233 NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791
JBrowse link
G Pten phosphatase and tensin homolog affects expression
multiple interactions
EXP Rimonabant affects the expression of PTEN mRNA
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of PTEN mRNA
CTD PMID:32833042 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PTGES2 mRNA] CTD PMID:19030233 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] CTD PMID:26209559 PMID:30769029 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA] CTD PMID:19030233 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Pyy peptide YY multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PYY mRNA] CTD PMID:19030233 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]; Rimonabant inhibits the reaction [Ethanol results in decreased expression of RAC1 protein] CTD PMID:30143782 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO Rimonabant inhibits the reaction [Dronabinol results in increased localization of RAF1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased localization of RAF1 protein] CTD PMID:12834810 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Ramp2 receptor activity modifying protein 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of RAMP2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RAMP2 mRNA]
CTD PMID:19030233 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBMS1 mRNA] CTD PMID:19030233 NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
JBrowse link
G Rbp4 retinol binding protein 4 decreases expression ISO rimonabant decreases expression of Rbp4 mRNA and protein in adipose tissue, aortic tissue and adipocytes RGD PMID:21585349 RGD:329853312 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBPJ mRNA] CTD PMID:19030233 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
ISO Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]
Rimonabant results in decreased expression of RELA protein
CTD PMID:21373835 PMID:26209559 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RFNG mRNA]
Rimonabant affects the expression of RFNG mRNA
CTD PMID:19030233 NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345
JBrowse link
G Rgs11 regulator of G-protein signaling 11 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RGS11 mRNA] CTD PMID:19030233 NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein] CTD PMID:31220554 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK3 protein] CTD PMID:31220554 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G rnf141 ring finger protein 141 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF141 mRNA] CTD PMID:19030233 NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118
JBrowse link
G Rnf185 ring finger protein 185 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RNF185 mRNA] CTD PMID:19030233 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF19A mRNA] CTD PMID:19030233 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
JBrowse link
G Rnf2 ring finger protein 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF2 mRNA] CTD PMID:19030233 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
JBrowse link
G Rnf6 ring finger protein 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF6 mRNA] CTD PMID:19030233 NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847
JBrowse link
G Rp9 RP9, pre-mRNA splicing factor multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RP9 mRNA] CTD PMID:19030233 NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175
JBrowse link
G Rpf2 ribosome production factor 2 homolog multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPF2 mRNA] CTD PMID:19030233 NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
JBrowse link
G Rpl18 ribosomal protein L18 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL18 mRNA] CTD PMID:19030233 NCBI chr 1:96,188,811...96,191,452
Ensembl chr 1:96,188,112...96,191,452
JBrowse link
G Rpl28 ribosomal protein L28 affects expression
multiple interactions
ISO Rimonabant affects the expression of RPL28 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL28 mRNA]
CTD PMID:19030233 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rpl41 ribosomal protein L41 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL41 mRNA] CTD PMID:19030233 NCBI chr 7:977,885...978,965 JBrowse link
G Rps10 ribosomal protein S10 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS10 mRNA] CTD PMID:19030233 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044
JBrowse link
G Rps15 ribosomal protein S15 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS15 mRNA] CTD PMID:19030233 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Rps28 ribosomal protein S28 affects expression ISO Rimonabant affects the expression of RPS28 mRNA CTD PMID:19030233 NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170
Ensembl chr16:14,607,801...14,609,170
Ensembl chr16:14,607,801...14,609,170
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Rimonabant results in decreased phosphorylation of RPS6 protein CTD PMID:30687088 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps8 ribosomal protein S8 affects expression
multiple interactions
ISO Rimonabant affects the expression of RPS8 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS8 mRNA]
CTD PMID:19030233 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rras2 RAS related 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RRAS2 mRNA] CTD PMID:19030233 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RXRB mRNA] CTD PMID:19030233 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Ryk receptor-like tyrosine kinase affects expression
multiple interactions
ISO Rimonabant affects the expression of RYK mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RYK mRNA]
CTD PMID:19030233 NCBI chr 8:103,419,338...103,492,083
Ensembl chr 8:103,419,275...103,491,698
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO Rimonabant results in increased expression of SCARB1 mRNA CTD PMID:20110567 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Rimonabant results in decreased expression of SCD1 mRNA CTD PMID:20110567 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SCD2 mRNA] CTD PMID:19030233 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Scoc short coiled-coil protein multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SCOC mRNA] CTD PMID:19030233 NCBI chr19:24,659,651...24,689,237
Ensembl chr19:24,659,651...24,693,217
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC62 mRNA] CTD PMID:19030233 NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC63 mRNA] CTD PMID:19030233 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link
G Sema3c semaphorin 3C multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEMA3C mRNA] CTD PMID:19030233 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
JBrowse link
G Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase affects expression ISO Rimonabant affects the expression of SEPSECS mRNA CTD PMID:19030233 NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
JBrowse link
G Septin2 septin 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEPTIN2 mRNA] CTD PMID:19030233 NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
JBrowse link
G Septin6 septin 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SEPTIN6 mRNA] CTD PMID:19030233 NCBI chr  X:116,153,255...116,230,334
Ensembl chr  X:116,153,255...116,230,115
JBrowse link
G Serpinb6a serpin family B member 6A multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SERPINB6A mRNA]
Rimonabant affects the expression of SERPINB6A mRNA
CTD PMID:19030233 NCBI chr17:30,871,468...30,989,703
Ensembl chr17:30,871,468...31,014,427
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Rimonabant results in decreased expression of SERPINE1 protein CTD PMID:17882151 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sestd1 SEC14 and spectrin domain containing 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SESTD1 mRNA]
Rimonabant affects the expression of SESTD1 mRNA
CTD PMID:19030233 NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SGTA mRNA] CTD PMID:19030233 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Sh3bgrl1 SH3 domain binding glutamate rich protein like 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SH3BGRL mRNA] CTD PMID:19030233 NCBI chr  X:74,167,029...74,263,783
Ensembl chr  X:74,166,871...74,263,783
JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SIPA1L1 mRNA]
Rimonabant affects the expression of SIPA1L1 mRNA
CTD PMID:19030233 NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SLC2A4 mRNA] CTD PMID:19030233 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc39a10 solute carrier family 39 member 10 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A10 mRNA] CTD PMID:19030233 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A8 mRNA] CTD PMID:19030233 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Smarca2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA] CTD PMID:19030233 NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression EXP Rimonabant results in decreased expression of SOCS1 mRNA CTD PMID:30365523 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression EXP Rimonabant results in decreased expression of SOCS3 mRNA CTD PMID:30365523 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 affects expression ISO Rimonabant affects the expression of SORBS2 mRNA CTD PMID:19030233 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPARC mRNA]
Rimonabant affects the expression of SPARC mRNA
CTD PMID:19030233 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPTBN1 mRNA]
Rimonabant affects the expression of SPTBN1 mRNA
CTD PMID:19030233 NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein] CTD PMID:16046413 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srp72 signal recognition particle 72 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SRP72 mRNA] CTD PMID:19030233 NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ST3GAL6 mRNA] CTD PMID:19030233 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein] CTD PMID:16046413 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO [MIR466J mRNA co-treated with Rimonabant] affects the expression of STAT6 mRNA; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STAT6 mRNA] CTD PMID:30910812 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stim2 stromal interaction molecule 2 multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of STIM2 mRNA]
Rimonabant affects the expression of STIM2 mRNA
CTD PMID:19030233 NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
JBrowse link
G Strn4 striatin 4 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STRN4 mRNA] CTD PMID:19030233 NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858
JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TCEA1 mRNA] CTD PMID:19030233 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
Ensembl chr15:14,631,454...14,668,745
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Rimonabant results in decreased expression of TGFB1 mRNA CTD PMID:30365523 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TGIF2 mRNA] CTD PMID:19030233 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
Ensembl chr17:145,333,418...145,348,596
JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases activity
EXP Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of TH protein]
Rimonabant results in increased activity of TH protein
CTD PMID:9188039 PMID:10700552 PMID:15882845 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions EXP Rimonabant inhibits the reaction [methanandamide affects the expression of THY1 mRNA] CTD PMID:17591864 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression EXP Rimonabant results in decreased expression of TIMP1 mRNA CTD PMID:21863215 PMID:30365523 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TMED7 mRNA] CTD PMID:19030233 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TNF]; Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]]
Rimonabant results in decreased expression of TNF mRNA
CTD PMID:20110567 PMID:30365523 PMID:30769029 PMID:32832534 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TOMM20 mRNA] CTD PMID:19030233 NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
JBrowse link
G Tpm4 tropomyosin 4 affects expression
multiple interactions
ISO Rimonabant affects the expression of TPM4 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TPM4 mRNA]
CTD PMID:19030233 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO Rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide binds to and results in increased activity of TRPV1 protein] CTD PMID:11278420 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Tsen2 tRNA splicing endonuclease subunit 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of TSEN2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSEN2 mRNA]
CTD PMID:19030233 NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
JBrowse link
G Tspan5 tetraspanin 5 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSPAN5 mRNA] CTD PMID:19030233 NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP Rimonabant results in increased expression of TXNRD1 mRNA CTD PMID:30365523 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Unc5b unc-5 netrin receptor B multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of UNC5B mRNA] CTD PMID:30910812 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
JBrowse link
G Usp46 ubiquitin specific peptidase 46 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP46 mRNA] CTD PMID:19030233 NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
JBrowse link
G Usp48 ubiquitin specific peptidase 48 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP48 mRNA] CTD PMID:19030233 NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO Rimonabant inhibits the reaction [Glucose results in increased expression of VCAM1 protein]
Rimonabant results in decreased expression of VCAM1 protein
CTD PMID:21373835 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcl vinculin multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VCL mRNA] CTD PMID:19030233 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein] CTD PMID:15313899 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions
affects expression
ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VIM mRNA]
Rimonabant affects the expression of VIM mRNA
CTD PMID:19030233 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VLDLR mRNA] CTD PMID:19030233 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Wdr26 WD repeat domain 26 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WDR26 mRNA] CTD PMID:19030233 NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
JBrowse link
G Wdr7 WD repeat domain 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of WDR7 mRNA] CTD PMID:19030233 NCBI chr18:57,165,482...57,448,568
Ensembl chr18:57,165,488...57,448,540
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WSB1 mRNA] CTD PMID:19030233 NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
JBrowse link
G Wwp1 WW domain containing E3 ubiquitin protein ligase 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWP1 mRNA] CTD PMID:19030233 NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWTR1 mRNA] CTD PMID:19030233 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
multiple interactions
ISO Rimonabant results in increased expression of XBP1 mRNA
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form]; Gemcitabine promotes the reaction [Rimonabant results in increased expression of XBP1 mRNA]
CTD PMID:21525939 PMID:31054322 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zdhhc2 zinc finger DHHC-type palmitoyltransferase 2 affects expression
multiple interactions
ISO Rimonabant affects the expression of ZDHHC2 mRNA
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZDHHC2 mRNA]
CTD PMID:19030233 NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ZDHHC7 mRNA] CTD PMID:19030233 NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673
JBrowse link
G Zhx1 zinc fingers and homeoboxes 1 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZHX1 mRNA] CTD PMID:19030233 NCBI chr 7:89,582,363...89,611,337
Ensembl chr 7:89,582,243...89,611,264
JBrowse link
G Znrf2 zinc and ring finger 2 multiple interactions ISO Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZNRF2 mRNA] CTD PMID:19030233 NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818
JBrowse link
G Zwilch zwilch kinetochore protein affects expression ISO Rimonabant affects the expression of ZWILCH mRNA CTD PMID:19030233 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
JBrowse link
SR 144528 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO SR 144528 inhibits the reaction [celastrol inhibits the reaction [Folic Acid results in increased expression of ACTA2 protein]] CTD PMID:29789558 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in decreased phosphorylation of AKT1 protein]; SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of AKT1 protein]; SR 144528 inhibits the reaction [methanandamide results in increased phosphorylation of AKT1 protein] CTD PMID:12834810 PMID:30733293 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF4 mRNA] CTD PMID:31054322 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF6 mRNA] CTD PMID:31054322 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Casp3 caspase 3 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased activity of CASP3 protein] CTD PMID:16818634 PMID:16818650 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO SR 144528 inhibits the reaction [CNR2 protein promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2 mRNA]]; SR 144528 inhibits the reaction [CNR2 protein promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2 protein]] CTD PMID:10218491 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in decreased expression of CDK1 protein] CTD PMID:16818634 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of CNP protein] CTD PMID:32956517 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO SR 144528 inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]] CTD PMID:11891798 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 affects binding
multiple interactions
ISO
EXP
SR 144528 binds to CNR2 protein
SR 144528 binds to and results in decreased activity of CNR2 protein
[SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; [SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to palmidrol analog; SR 144528 binds to and results in decreased activity of CNR2 protein; SR 144528 inhibits the reaction [[3-(1,1-dimethyl-heptyl)-1-9-dihydroxy-benzo(c)chromen-6-one binds to and results in increased activity of CNR2 protein] which results in decreased susceptibility to Paclitaxel]; SR 144528 inhibits the reaction [[AM 1241 binds to and results in increased activity of CNR2 protein] which results in decreased susceptibility to Paclitaxel]; SR 144528 inhibits the reaction [CNR2 protein affects the susceptibility to Dronabinol]
[SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; SR 144528 binds to and results in decreased activity of CNR2 protein; SR 144528 inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [[virodhamine binds to and results in increased activity of CNR2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2 mRNA]]; SR 144528 inhibits the reaction [CNR2 protein promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2 protein]]; SR 144528 inhibits the reaction [CNR2 protein promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL8 mRNA]]; SR 144528 inhibits the reaction [CNR2 protein promotes the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL8 protein]]; SR 144528 inhibits the reaction [Dronabinol inhibits the reaction [ERBB2 protein binds to CNR2 protein]]
CTD PMID:10218491 PMID:10617657 PMID:10688601 PMID:12509806 PMID:15115777 More... NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of DDIT3 mRNA] CTD PMID:31054322 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol inhibits the reaction [ERBB2 protein binds to CNR2 protein]]; SR 144528 inhibits the reaction [Dronabinol inhibits the reaction [ERBB2 protein binds to ERBB2 protein]]; SR 144528 inhibits the reaction [Dronabinol results in decreased expression of and affects the phosphorylation of ERBB2 protein] CTD PMID:30733293 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO SR 144528 inhibits the reaction [celastrol inhibits the reaction [Folic Acid results in increased expression of FN1 protein]] CTD PMID:29789558 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of GATA3 mRNA] CTD PMID:14741435 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of HSPA5 mRNA] CTD PMID:31054322 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Ifng interferon gamma multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in decreased expression of IFNG mRNA]; SR 144528 inhibits the reaction [Dronabinol results in decreased expression of IFNG protein] CTD PMID:12446015 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions ISO SR 144528 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]] CTD PMID:15821753 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B multiple interactions ISO SR 144528 inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]] CTD PMID:15821753 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; SR 144528 inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]] CTD PMID:15748152 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in decreased expression of IL2 mRNA] CTD PMID:12446015 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of IL4 mRNA]; SR 144528 inhibits the reaction [Dronabinol results in increased expression of IL4 protein] CTD PMID:12446015 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of IL5 mRNA] CTD PMID:12446015 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO SR 144528 inhibits the reaction [caryophyllene inhibits the reaction [TNF protein results in increased expression of IRF1 protein]] CTD PMID:28624443 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Mag myelin-associated glycoprotein multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of MAG protein] CTD PMID:32956517 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK1 protein]; SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; SR 144528 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein] CTD PMID:12834810 PMID:30733293 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK3 protein]; SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; SR 144528 inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein] CTD PMID:12834810 PMID:30733293 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK8 protein] CTD PMID:24184660 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK9 protein] CTD PMID:24184660 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mbp myelin basic protein multiple interactions EXP SR 144528 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MBP protein] CTD PMID:17880390 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mog myelin oligodendrocyte glycoprotein multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of MOG protein] CTD PMID:32956517 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] CTD PMID:15748152 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of NUPR1 mRNA] CTD PMID:16818650 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased localization of RAF1 protein]; SR 144528 inhibits the reaction [methanandamide results in increased localization of RAF1 protein] CTD PMID:12834810 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO SR 144528 inhibits the reaction [Dronabinol results in increased expression of TGFB1 protein] CTD PMID:11779138 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO SR 144528 inhibits the reaction [caryophyllene inhibits the reaction [TNF protein results in increased expression of IRF1 protein]]; SR 144528 inhibits the reaction [caryophyllene inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]] CTD PMID:28624443 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO SR 144528 inhibits the reaction [caryophyllene inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]] CTD PMID:28624443 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO SR 144528 inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein] CTD PMID:15313899 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form] CTD PMID:31054322 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        pharmacological role 19101
          antagonist 17266
            cannabinoid receptor antagonist 463
              CB1 receptor antagonist + 453
              CB2 receptor antagonist + 38
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