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ONTOLOGY REPORT - ANNOTATIONS


Term:promegestone
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Accession:CHEBI:73390 term browser browse the term
Definition:A progestin consisting of 17beta-propionylestra-4,9-dien-3-one substituted at position 17 by a methyl group.
Synonyms:exact_synonym: (17beta)-17-methyl-17-propionylestra-4,9-dien-3-one
 related_synonym: 17,21-dimethyl-19-norpregna-4,9(10)-diene-3,20-dione;   17alpha-methyl-17-propionylestra-4,9-dien-3-one;   Formula=C22H30O2;   InChI=1S/C22H30O2/c1-4-20(24)22(3)12-10-19-18-7-5-14-13-15(23)6-8-16(14)17(18)9-11-21(19,22)2/h13,18-19H,4-12H2,1-3H3/t18-,19+,21+,22-/m1/s1;   InChIKey=QFFCYTLOTYIJMR-XMGTWHOFSA-N;   R 5020;   RU5020;   SMILES=[H][C@@]12CCC3=CC(=O)CCC3=C1CC[C@@]1(C)[C@@]2([H])CC[C@]1(C)C(=O)CC;   promegestona;   promegestonum
 alt_id: CHEBI:34933
 xref: CAS:34184-77-5 "ChemIDplus";   CAS:34184-77-5 "KEGG COMPOUND";   Drug_Central:2285 "DrugCentral";   KEGG:C14208;   KEGG:D08431
 xref_mesh: MESH:D011397
 xref: PMID:1563574 "Europe PMC";   PMID:18979300 "Europe PMC";   PMID:19250196 "Europe PMC";   PMID:19429233 "Europe PMC";   PMID:19962254 "Europe PMC";   PMID:21228216 "Europe PMC";   PMID:23466250 "Europe PMC";   PMID:23597562 "Europe PMC";   PMID:3386236 "Europe PMC";   PMID:3748873 "Europe PMC";   PMID:570871 "Europe PMC";   PMID:6169181 "Europe PMC";   PMID:7647331 "Europe PMC";   PMID:7979190 "Europe PMC";   PMID:885117 "Europe PMC";   PMID:9749835 "Europe PMC";   Reaxys:5104746 "Reaxys";   Wikipedia:Promegestone


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promegestone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 JBrowse link 19 41,805,252 41,860,076 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Arid1a AT-rich interaction domain 1A JBrowse link 5 151,904,687 151,977,973 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:6480464
G Dlg5 discs large MAGUK scaffold protein 5 JBrowse link 15 120,213 230,312 RGD:6480464
G Elf5 E74 like ETS transcription factor 5 JBrowse link 3 93,333,514 93,374,454 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:6480464
G Gpsm2 G-protein signaling modulator 2 JBrowse link 2 211,480,120 211,528,096 RGD:6480464
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 JBrowse link 19 50,246,404 50,317,892 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Myo10 myosin X JBrowse link 2 77,868,398 78,072,443 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Qsox1 quiescin sulfhydryl oxidase 1 JBrowse link 13 73,423,396 73,460,890 RGD:6480464
G Rbbp7 RB binding protein 7, chromatin remodeling factor JBrowse link X 33,648,682 33,665,821 RGD:6480464
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 JBrowse link 1 244,615,811 244,783,736 RGD:6480464
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:6480464
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 JBrowse link 10 87,116,827 87,138,890 RGD:6480464
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:6480464
G Sp3 Sp3 transcription factor JBrowse link 3 59,644,579 59,689,011 RGD:6480464
G Tigar TP53 induced glycolysis regulatory phosphatase JBrowse link 4 159,635,145 159,654,108 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464
G Zfp366 zinc finger protein 366 JBrowse link 2 29,410,169 29,498,661 RGD:6480464
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      application 19225
        pharmaceutical 19089
          drug 19089
            antineoplastic agent 16561
              promegestone 34
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      ketone 15784
                                        oxo steroid 9257
                                          3-oxo steroid 8780
                                            3-oxo-Delta(4) steroid 7905
                                              promegestone 34
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.