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Accession:CHEBI:73378 term browser browse the term
Definition:A member of the class of ergot alkaloids that is known to act on serotonin and dopamine receptors.
Synonyms:exact_synonym: N'-[(8alpha)-1,6-dimethylergolin-8-yl]-N,N-dimethylsulfuric diamide
 related_synonym: Formula=C18H26N4O2S;   InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1;   InChIKey=JLVHTNZNKOSCNB-YSVLISHTSA-N;   N'-(1,6-Dimethylergolin-8alpha-yl)-N,N-dimethylsulfamide;   SMILES=C1=C2C3=C(C=CC=C3[C@@]4([C@@](C2)(N(C[C@H](C4)NS(N(C)C)(=O)=O)C)[H])[H])N1C;   mesulergina;   mesulerginum
 xref: CAS:64795-35-3 "ChemIDplus";   LINCS:LSM-4045
 xref_mesh: MESH:C031649
 xref: PMID:21190911 "Europe PMC";   PMID:22313641 "Europe PMC";   PMID:23597562 "Europe PMC";   PMID:2895480 "Europe PMC";   PMID:3428838 "Europe PMC";   PMID:3708600 "Europe PMC";   PMID:3881692 "Europe PMC";   PMID:3895033 "Europe PMC";   PMID:4067602 "Europe PMC";   PMID:6230246 "Europe PMC";   PMID:6386276 "Europe PMC";   PMID:6488683 "Europe PMC";   PMID:6527137 "Europe PMC";   Patent:US4515950;   Reaxys:714438 "Reaxys";   Wikipedia:Mesulergine

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mesulergine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        pharmacological role 18798
          neurotransmitter agent 16401
            serotonergic drug 3913
              serotonergic antagonist 2221
                mesulergine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    main group molecular entity 19622
                      s-block molecular entity 19388
                        hydrogen molecular entity 19377
                          hydrides 18283
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17001
                                  azane 16694
                                    ammonia 16691
                                      organic amino compound 16690
                                        polyamine 8073
                                          diamine 8000
                                            ergoline 17
                                              mesulergine 4
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.