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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:protein-sequencing agent
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Accession:CHEBI:73352 term browser browse the term
Definition:Any agent used to determine the amino-acid sequence in a polypeptide.
Synonyms:related_synonym: protein-sequencing agents;   sequencing agent;   sequencing agents


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1-fluoro-2,4-dinitrobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression ISO Dinitrofluorobenzene results in increased expression of ADM mRNA CTD PMID:23999411 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akirin2 akirin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of AKIRIN2 mRNA CTD PMID:23999411 NCBI chr 5:50,001,945...50,016,544
Ensembl chr 5:50,002,184...50,016,539
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of AKT1 protein CTD PMID:23445166 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Dinitrofluorobenzene results in increased expression of AQP3 mRNA CTD PMID:21362464 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arg2 arginase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of ARG2 mRNA CTD PMID:23999411 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Dinitrofluorobenzene results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of BABAM2 mRNA CTD PMID:23999411 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
Dinitrofluorobenzene results in increased expression of CCL2 mRNA
CTD PMID:15719370, PMID:21362464 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL3 mRNA CTD PMID:15719370 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL4 mRNA
Dinitrofluorobenzene results in increased expression of CCL4 protein
CTD PMID:15719370, PMID:18353026 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Dinitrofluorobenzene results in increased expression of CCL5 mRNA; Dinitrofluorobenzene results in increased expression of CCL5 protein CTD PMID:15719370 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Dinitrofluorobenzene results in increased expression of CCNE2 mRNA CTD PMID:23999411 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of CCR2 mRNA
[CCL2 protein results in increased expression of CCR2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD PMID:21362464
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CCR6 protein CTD PMID:15924226 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Cd83 CD83 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD83 protein CTD PMID:21362464 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd86 CD86 molecule increases expression ISO Dinitrofluorobenzene results in increased expression of CD86 protein CTD PMID:21362464 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO Dinitrofluorobenzene affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Dinitrofluorobenzene results in increased expression of CREM mRNA CTD PMID:21362464 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
ISO Dinitrofluorobenzene results in increased expression of CXCL10 mRNA; Dinitrofluorobenzene results in increased expression of CXCL10 protein
Dinitrofluorobenzene results in decreased expression of CXCL10 mRNA
CTD PMID:15719370, PMID:23445166 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Dinitrofluorobenzene results in increased expression of CXCL1 mRNA CTD PMID:15719370 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Dinitrofluorobenzene results in decreased expression of CXCR4 protein CTD PMID:15924226 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO Dinitrofluorobenzene results in increased expression of CYTIP mRNA CTD PMID:21362464 NCBI chr 3:44,150,494...44,225,723
Ensembl chr 3:44,150,992...44,177,689
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of DHRS2 mRNA CTD PMID:23999411 NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Dinitrofluorobenzene results in increased expression of DNAJB4 mRNA CTD PMID:23999411 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EIF1 mRNA CTD PMID:23999411 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Dinitrofluorobenzene results in increased expression of EPC1 mRNA CTD PMID:23999411 NCBI chr17:57,303,968...57,394,975
Ensembl chr17:57,304,933...57,394,985
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Dinitrofluorobenzene results in increased expression of FOSB mRNA CTD PMID:23999411 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLC mRNA CTD PMID:23999411 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Dinitrofluorobenzene results in increased expression of GCLM mRNA CTD PMID:23999411 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Dinitrofluorobenzene results in increased expression of H2AX mRNA CTD PMID:23999411 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HMOX1 mRNA CTD PMID:23445166, PMID:25091725 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Dinitrofluorobenzene results in increased expression of HSPA1A mRNA CTD PMID:23999411 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Dinitrofluorobenzene results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO BIRB 796 inhibits the reaction [Dinitrofluorobenzene results in increased expression of ICAM1 protein] CTD PMID:19427879 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of IFNG mRNA; Dinitrofluorobenzene results in increased expression of IFNG protein
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IFNG mRNA]
CTD PMID:11243917, PMID:11244134, PMID:23499868 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 increases expression ISO Dinitrofluorobenzene results in increased expression of IL10 mRNA CTD PMID:11243917, PMID:23499868 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B increases expression ISO Dinitrofluorobenzene results in increased expression of IL12B mRNA CTD PMID:11708898 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases response to substance ISO IL15RA protein results in increased susceptibility to Dinitrofluorobenzene CTD PMID:15719370 NCBI chr17:70,451,861...70,481,838
Ensembl chr17:70,451,411...70,481,750
JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of IL17A mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of IL17A mRNA]
CTD PMID:23499868 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17f interleukin 17F increases expression ISO Dinitrofluorobenzene results in increased expression of IL17F mRNA CTD PMID:23445166 NCBI chr 9:26,885,702...26,897,219
Ensembl chr 9:26,885,708...26,897,219
JBrowse link
G Il1a interleukin 1 alpha increases expression
affects secretion
ISO Dinitrofluorobenzene results in increased expression of IL1A mRNA; Dinitrofluorobenzene results in increased expression of IL1A protein
Dinitrofluorobenzene affects the secretion of IL1A protein
CTD PMID:8006454, PMID:12781210 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il2 interleukin 2 increases expression ISO Dinitrofluorobenzene results in increased expression of IL2 mRNA; Dinitrofluorobenzene results in increased expression of IL2 protein CTD PMID:11244134, PMID:22381623 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression ISO Dinitrofluorobenzene results in increased expression of IL4 mRNA CTD PMID:23499868 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Dinitrofluorobenzene results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Dinitrofluorobenzene results in increased expression of MAFF mRNA CTD PMID:23999411 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]
CTD PMID:27129696 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK14 protein CTD PMID:19427879 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]
CTD PMID:27129696 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]
CTD PMID:27129696 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]
CTD PMID:27129696 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mif macrophage migration inhibitory factor increases expression ISO Dinitrofluorobenzene results in increased expression of MIF mRNA CTD PMID:11244134 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of MXD1 mRNA CTD PMID:21362464 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Dinitrofluorobenzene results in increased expression of NAMPT mRNA CTD PMID:21362464 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NFE2L2 protein CTD PMID:19427879, PMID:26022718 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO Dinitrofluorobenzene results in decreased expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of NQO1 mRNA CTD PMID:23445166 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NR2F2 mRNA CTD PMID:23999411 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Dinitrofluorobenzene results in increased expression of NTRK2 mRNA CTD PMID:23999411 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Peg10 paternally expressed 10 increases expression ISO Dinitrofluorobenzene results in increased expression of PEG10 mRNA CTD PMID:23999411 NCBI chr 4:29,795,524...29,804,517 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Dinitrofluorobenzene results in increased expression of PMAIP1 mRNA CTD PMID:23999411 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Dinitrofluorobenzene results in increased expression of PTGS2 mRNA; Dinitrofluorobenzene results in increased expression of PTGS2 protein
[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which affects the susceptibility to Dinitrofluorobenzene
CTD PMID:21362464 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Dinitrofluorobenzene results in increased expression of PTX3 mRNA CTD PMID:23999411 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Dinitrofluorobenzene results in increased expression of RGS16 mRNA CTD PMID:23999411 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Dinitrofluorobenzene results in increased expression of SLC2A3 mRNA CTD PMID:21362464 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases response to substance
ISO Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] CTD PMID:14555839 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO Dinitrofluorobenzene results in increased expression of TAF7 mRNA CTD PMID:23999411 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TGFB1 mRNA CTD PMID:11244134 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 increases expression ISO Dinitrofluorobenzene results in increased expression of TICAM2 mRNA CTD PMID:23999411 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Tnf tumor necrosis factor affects expression
multiple interactions
increases expression
ISO Dinitrofluorobenzene affects the expression of TNF mRNA
oleanolic acid 3-acetate inhibits the reaction [Dinitrofluorobenzene results in increased expression of TNF mRNA]
CTD PMID:20385217, PMID:23499868 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Dinitrofluorobenzene results in increased expression of TNFRSF10A mRNA CTD PMID:23999411 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIB1 mRNA CTD PMID:23999411 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Trim27 tripartite motif-containing 27 increases expression ISO Dinitrofluorobenzene results in increased expression of TRIM27 mRNA CTD PMID:23999411 NCBI chr17:45,613,863...45,626,212
Ensembl chr17:45,613,864...45,626,212
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Dinitrofluorobenzene results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 increases expression ISO Dinitrofluorobenzene results in increased expression of XCL1 mRNA CTD PMID:15719370 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
G Zfp870 zinc finger protein 870 increases expression ISO Dinitrofluorobenzene results in increased expression of ZNF670 mRNA CTD PMID:23999411 NCBI chr 7:15,158,673...15,172,489
Ensembl chr 7:15,159,422...15,163,866
JBrowse link
G Zxdb zinc finger, X-linked, duplicated B increases expression ISO Dinitrofluorobenzene results in increased expression of ZXDB mRNA CTD PMID:23999411 NCBI chr  X:64,092,609...64,097,967 JBrowse link

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  CHEBI ontology 19787
    role 19734
      application 19393
        protein-sequencing agent 76
          1-fluoro-2,4-dinitrobenzene 76
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.