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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:scabicide
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Accession:CHEBI:73333 term browser browse the term
Definition:An acaricide that kills mites of the genus Sarcoptes.
Synonyms:related_synonym: scabicides
 xref: Wikipedia:Scabicide


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benzyl benzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO benzyl benzoate results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Cd86 CD86 molecule increases expression ISO benzyl benzoate results in increased expression of CD86 protein CTD PMID:29540657 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO benzyl benzoate inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:19338011 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO benzyl benzoate inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:19338011 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO benzyl benzoate results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B decreases activity ISO benzyl benzoate results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Nefh neurofilament heavy affects expression EXP benzyl benzoate affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO benzyl benzoate results in increased expression of TFF1 mRNA CTD PMID:19338011 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
crotamiton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO crotamiton results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
ivermectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects abundance
increases expression
decreases activity
increases export
decreases response to substance
multiple interactions
increases response to substance
affects binding
affects response to substance
ISO ABCB1 gene polymorphism affects the abundance of Ivermectin
Ivermectin results in increased expression of ABCB1A mRNA
Ivermectin results in decreased activity of ABCB1A protein
ABCB1A protein results in increased export of Ivermectin
ABCB1A protein results in decreased susceptibility to Ivermectin
[ABCB1A protein co-treated with ABCB1B protein] affects the susceptibility to Ivermectin; Ivermectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin results in increased expression of and results in increased stability of ABCB1A mRNA; Ivermectin results in increased susceptibility to [ABCB1A protein results in increased transport of Xanthenes]
ABCB1A gene mutant form results in increased susceptibility to Ivermectin; ABCB1A protein mutant form results in increased susceptibility to Ivermectin
Ivermectin results in decreased activity of ABCB1 protein
ABCB1 protein affects the abundance of Ivermectin
Ivermectin inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]; Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
Ivermectin binds to ABCB1 protein
ABCB1 gene polymorphism affects the susceptibility to Ivermectin
CTD PMID:8917702, PMID:8949985, PMID:9144452, PMID:17134887, PMID:18633165, PMID:19161460, PMID:20513441, PMID:20595473, PMID:20630055, PMID:22024132, PMID:22834856, PMID:24998875, PMID:25865432 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B multiple interactions
increases expression
ISO [ABCB1A protein co-treated with ABCB1B protein] affects the susceptibility to Ivermectin; Ivermectin results in increased expression of and results in increased stability of ABCB1B mRNA
Ivermectin results in increased expression of ABCB1B mRNA
CTD PMID:19161460, PMID:22024132, PMID:24998875 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO Ivermectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
Ivermectin results in decreased activity of ABCC1 protein
CTD PMID:25865432 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Ivermectin results in increased expression of ABCC2 mRNA CTD PMID:24998875 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Ivermectin results in increased expression of ABCG2 mRNA CTD PMID:24998875 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression
decreases expression
multiple interactions
ISO Ivermectin affects the expression of ACACA mRNA
Ivermectin results in decreased expression of ACACA mRNA
Ivermectin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ACACA protein]
Ivermectin inhibits the reaction [Palmitic Acid results in decreased phosphorylation of ACACA protein]
CTD PMID:30738135, PMID:31199990 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Adcy7 adenylate cyclase 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ADCY7 mRNA CTD PMID:16861626 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Adm adrenomedullin decreases expression ISO Ivermectin results in decreased expression of ADM mRNA CTD PMID:28942281 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO Ivermectin results in increased expression of ALDH1L2 mRNA CTD PMID:28942281 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression ISO Ivermectin results in increased expression of ANGPTL6 mRNA CTD PMID:28942281 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of ARL4C mRNA CTD PMID:16861626 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Ivermectin results in increased expression of ATF4 mRNA CTD PMID:28942281 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Ivermectin results in increased expression of ATF5 mRNA CTD PMID:28942281 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Ivermectin results in increased expression of ATF6 mRNA CTD PMID:28942281 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of BAG3 mRNA CTD PMID:16861626 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Ivermectin results in increased expression of BAX protein CTD PMID:28811376 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO Ivermectin inhibits the reaction [geranylgeranic acid results in increased expression of BBC3 mRNA] CTD PMID:24658405 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Ivermectin results in decreased expression of BNIP3 mRNA CTD PMID:28942281 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Camp cathelicidin antimicrobial peptide decreases expression ISO Ivermectin results in decreased expression of CAMP mRNA; Ivermectin results in decreased expression of CAMP protein CTD PMID:28653460 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Ivermectin results in decreased activity of CAT protein
Thioctic Acid inhibits the reaction [Ivermectin results in decreased activity of CAT protein]
CTD PMID:28880400 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCL3 protein CTD PMID:16861626 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CCR7 mRNA CTD PMID:16861626 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCT3 mRNA CTD PMID:16861626 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cd36 CD36 molecule affects expression ISO Ivermectin affects the expression of CD36 mRNA CTD PMID:31199990 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Ivermectin results in increased expression of CDH1 CTD PMID:26078298 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Ivermectin results in increased expression of CDKN1A protein CTD PMID:28811376 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Ivermectin results in increased expression of CDKN1B protein CTD PMID:28811376 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression
multiple interactions
ISO Ivermectin affects the expression of CEBPA mRNA
Ivermectin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]; Rosiglitazone affects the reaction [Ivermectin affects the expression of CEBPA mRNA]
CTD PMID:31199990 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Ivermectin results in increased expression of COX6A2 mRNA; Ivermectin results in increased expression of COX6A2 protein CTD PMID:28942281 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression
multiple interactions
ISO Ivermectin affects the expression of CPT1A mRNA
Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
CTD PMID:30738135, PMID:31199990 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crp C-reactive protein increases expression ISO Ivermectin results in increased expression of CRP protein CTD PMID:8555762 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CTSL mRNA CTD PMID:16861626 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
ISO Ivermectin results in decreased activity of CYP1A1 protein
Ivermectin results in increased expression of CYP1A1 mRNA
CTD PMID:18420780, PMID:24998875 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Ivermectin results in increased expression of CYP1A2 mRNA CTD PMID:24998875 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Ivermectin results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity
increases expression
ISO Ivermectin results in decreased activity of CYP2B10 protein
Ivermectin results in increased expression of CYP2B10 mRNA
CTD PMID:18420780, PMID:24998875 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Ivermectin results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Ivermectin results in decreased activity of CYP2D6 protein
Ivermectin results in decreased activity of CYP2D22 protein
CTD PMID:11124226, PMID:18420780 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Ivermectin results in decreased activity of CYP2E1 protein CTD PMID:18420780 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects expression
multiple interactions
ISO Ivermectin results in increased expression of DDIT3 mRNA
Ivermectin affects the expression of DDIT3 mRNA
Ivermectin promotes the reaction [Palmitic Acid results in increased expression of DDIT3 protein]
CTD PMID:28942281, PMID:30738135, PMID:31199990 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DNAJB1 mRNA CTD PMID:16861626 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DPYSL2 mRNA CTD PMID:16861626 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Ivermectin results in increased expression of EDEM1 mRNA CTD PMID:28942281 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 decreases expression ISO Ivermectin results in decreased expression of EGLN3 mRNA CTD PMID:28942281 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Ivermectin results in increased expression of ESR1 CTD PMID:26078298 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fabp4 fatty acid binding protein 4 affects expression
multiple interactions
ISO Ivermectin affects the expression of FABP4 mRNA
Rosiglitazone affects the reaction [Ivermectin affects the expression of FABP4 mRNA]
CTD PMID:31199990 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fasn fatty acid synthase affects expression ISO Ivermectin affects the expression of FASN mRNA CTD PMID:31199990 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Ivermectin results in increased expression of GDF15 mRNA CTD PMID:28942281 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of GEM mRNA CTD PMID:16861626 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Glra1 glycine receptor, alpha 1 increases activity
multiple interactions
affects activity
ISO Ivermectin results in increased activity of GLRA1 protein mutant form
Ivermectin affects the reaction [Glycine affects the activity of GLRA1 protein mutant form]
Ivermectin affects the activity of GLRA1 protein mutant form
CTD PMID:25231486, PMID:27958714 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Glra3 glycine receptor, alpha 3 affects expression ISO Ivermectin affects the expression of GLRA3 mRNA CTD PMID:31199990 NCBI chr16:37,676,959...37,908,221
Ensembl chr16:37,676,962...38,063,821
JBrowse link
G Glrb glycine receptor, beta affects expression ISO Ivermectin affects the expression of GLRB mRNA CTD PMID:31199990 NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
JBrowse link
G Gpr183 G protein-coupled receptor 183 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of GPR183 mRNA CTD PMID:16861626 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AA1 mRNA CTD PMID:16861626 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA CTD PMID:16861626 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions
EXP Ivermectin results in increased expression of HSPA1A mRNA
Thioctic Acid inhibits the reaction [Ivermectin results in increased expression of HSPA1A mRNA]
CTD PMID:28880400 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA4 mRNA CTD PMID:16861626 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Ivermectin results in increased expression of HSPA5 protein CTD PMID:30738135 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression ISO Ivermectin results in increased expression of HSPA9 mRNA CTD PMID:28942281 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression
ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPD1 mRNA
Ivermectin results in increased expression of HSPD1 mRNA
CTD PMID:16861626, PMID:28942281 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPE1 mRNA CTD PMID:16861626 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPH1 mRNA CTD PMID:16861626 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression
multiple interactions
EXP Ivermectin results in increased expression of IGFBP3 mRNA
Thioctic Acid inhibits the reaction [Ivermectin results in increased expression of IGFBP3 mRNA]
CTD PMID:28880400 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL10 protein CTD PMID:16861626 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO Ivermectin results in increased expression of LONP1 mRNA CTD PMID:28942281 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of MAP3K8 mRNA CTD PMID:16861626 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein] CTD PMID:19168156 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein] CTD PMID:19168156 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:19168156 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mxd1 max dimerization protein 1 multiple interactions ISO Ivermectin inhibits the reaction [MXD1 protein binds to SIN3A protein] CTD PMID:26078298 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Ivermectin results in decreased expression of NANOG mRNA; Ivermectin results in decreased expression of NANOG protein CTD PMID:29257278 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Ivermectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression ISO Ivermectin results in decreased expression of NDRG1 mRNA CTD PMID:28942281 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:19168156 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Ivermectin results in decreased expression of NQO1 mRNA; Ivermectin results in decreased expression of NQO1 protein CTD PMID:22021338 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
increases expression
affects expression
ISO Ivermectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]
Ivermectin results in increased expression of NR1H4 mRNA
Ivermectin affects the expression of NR1H4 mRNA
CTD PMID:27773686, PMID:30738135, PMID:31199990 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Ivermectin results in increased expression of NUPR1 mRNA CTD PMID:28942281 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G P2rx4 purinergic receptor P2X 4 multiple interactions
increases activity
ISO Ivermectin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]
Ivermectin results in increased activity of P2RX4 protein
CTD PMID:19560503, PMID:21638035, PMID:30545933 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO Ivermectin results in increased expression of PARP1 protein modified form CTD PMID:28811376 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pfkl phosphofructokinase, liver type decreases expression ISO Ivermectin results in decreased expression of PFKL mRNA CTD PMID:28942281 NCBI chr20:11,393,860...11,415,889
Ensembl chr20:11,393,877...11,415,882
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Ivermectin results in decreased expression of POU5F1 mRNA; Ivermectin results in decreased expression of POU5F1 protein CTD PMID:29257278 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
ISO Ivermectin results in decreased expression of PPARA mRNA
Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA]
CTD PMID:30738135 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
multiple interactions
ISO Ivermectin affects the expression of PPARG mRNA
Ivermectin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]; Rosiglitazone affects the reaction [Ivermectin affects the expression of PPARG mRNA]
CTD PMID:31199990 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPID mRNA CTD PMID:16861626 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPIF mRNA CTD PMID:16861626 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of PTGES3 mRNA CTD PMID:16861626 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 mRNA]; Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:19168156 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 increases expression ISO Ivermectin results in increased expression of RPP14 mRNA CTD PMID:28942281 NCBI chr15:18,625,963...18,636,157
Ensembl chr15:18,625,964...18,632,536
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Ivermectin results in decreased expression of SERPINE1 mRNA CTD PMID:28942281 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sin3a SIN3 transcription regulator family member A multiple interactions ISO Ivermectin inhibits the reaction [MXD1 protein binds to SIN3A protein] CTD PMID:26078298 NCBI chr 8:61,748,590...61,803,314
Ensembl chr 8:61,762,768...61,803,099
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of SKAP2 mRNA CTD PMID:16861626 NCBI chr 4:81,816,778...81,968,832
Ensembl chr 4:81,818,569...81,968,832
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Ivermectin results in decreased expression of SLC2A1 mRNA CTD PMID:28942281 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 affects expression ISO Ivermectin affects the expression of SLC2A4 mRNA CTD PMID:31199990 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO Ivermectin results in decreased expression of SOX2 mRNA; Ivermectin results in decreased expression of SOX2 protein CTD PMID:29257278 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA CTD PMID:16861626 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G St13 ST13, Hsp70 interacting protein multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ST13 mRNA CTD PMID:16861626 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of TCP1 mRNA CTD PMID:16861626 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tfrc transferrin receptor decreases expression ISO Ivermectin results in decreased expression of TFRC mRNA CTD PMID:28942281 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TGIF1 mRNA CTD PMID:16861626 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression ISO Ivermectin results in decreased expression of TLR2 protein CTD PMID:28653460 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Ivermectin results in decreased expression of TLR4 mRNA CTD PMID:28653460 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Ivermectin results in decreased expression of TNF mRNA CTD PMID:28653460 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Ivermectin inhibits the reaction [geranylgeranic acid affects the localization of TP53 protein mutant form] CTD PMID:24658405 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Ivermectin results in increased expression of TRIB3 mRNA CTD PMID:28942281 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TSC22D1 mRNA CTD PMID:16861626 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
malaoxon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
[malaoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]
malaoxon metabolite results in decreased activity of ACHE protein; malaoxon results in decreased activity of ACHE protein
Dichlorvos promotes the reaction [malaoxon results in decreased activity of ACHE protein]; K075 compound inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]
CTD PMID:597376, PMID:4859365, PMID:8783813, PMID:9268605, PMID:9515941, PMID:20406208, PMID:21251949, PMID:21354413, PMID:27132127, PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Alb albumin affects binding ISO malaoxon binds to ALB protein CTD PMID:15525694 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Bche butyrylcholinesterase affects binding ISO malaoxon binds to BCHE protein; malaoxon binds to BCHE protein modified form CTD PMID:18514178 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cldn5 claudin 5 multiple interactions
decreases expression
EXP [malaoxon co-treated with Lead] results in decreased expression of CLDN5 protein
malaoxon results in decreased expression of CLDN5 protein
CTD PMID:20970449 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Ocln occludin multiple interactions
decreases expression
EXP [malaoxon co-treated with Lead] results in decreased expression of OCLN protein
malaoxon results in decreased expression of OCLN protein
CTD PMID:20970449 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity ISO malaoxon results in decreased activity of PNPLA6 protein CTD PMID:9268605 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO PON1 affects the susceptibility to [diazoxon co-treated with malaoxon]; PON1 affects the susceptibility to [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate co-treated with malaoxon] CTD PMID:19371602 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
EXP [malaoxon co-treated with Lead] results in decreased expression of TJP1 protein
malaoxon results in decreased expression of TJP1 protein
CTD PMID:20970449 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tjp2 tight junction protein 2 multiple interactions
decreases expression
EXP [malaoxon co-treated with Lead] results in decreased expression of TJP2 protein
malaoxon results in decreased expression of TJP2 protein
CTD PMID:20970449 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 increases expression EXP malaoxon results in increased expression of TRPC1 mRNA; malaoxon results in increased expression of TRPC1 protein CTD PMID:22674931 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 increases expression EXP malaoxon results in increased expression of TRPC4 mRNA; malaoxon results in increased expression of TRPC4 protein CTD PMID:22674931 NCBI chr 2:143,433,102...143,605,757
Ensembl chr 2:143,475,323...143,604,972
JBrowse link
malathion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
[Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]
[Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in increased activity of ACHE protein; Taurine inhibits the reaction [Malathion results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]
CTD PMID:2380476, PMID:4859365, PMID:14713564, PMID:18617161, PMID:19429256, PMID:19784758, PMID:21628957, PMID:21723318, PMID:21983245, PMID:23774768, PMID:28987951, PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression ISO Malathion results in decreased expression of ACSM1 mRNA CTD PMID:17311802 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Add3 adducin 3 increases expression EXP Malathion results in increased expression of ADD3 mRNA CTD PMID:19784758 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Aff1 AF4/FMR2 family, member 1 increases expression ISO Malathion results in increased expression of AFF1 mRNA mutant form CTD PMID:28624474 NCBI chr14:7,222,883...7,384,916
Ensembl chr14:7,226,586...7,384,876
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [prothioconazole co-treated with terbutylazine co-treated with bitertanol co-treated with cypermethrin co-treated with Malathion] results in increased activity of AHR protein CTD PMID:25684042 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Malathion results in increased expression of AKR1C2 mRNA CTD PMID:16079077 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Ar androgen receptor multiple interactions ISO [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein CTD PMID:23871939 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions
EXP
ISO
Malathion results in decreased expression of BAX mRNA
Malathion results in increased expression of BAX protein
Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein]
CTD PMID:23774768, PMID:30769050 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity
decreases activity
ISO
EXP
Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of BCHE protein]
Malathion results in increased activity of BCHE protein
CTD PMID:17364237, PMID:18617161, PMID:21983245, PMID:25180440 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
EXP
ISO
Malathion results in decreased expression of BCL2 mRNA
Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein]
CTD PMID:23774768, PMID:30769050 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Brd7 bromodomain containing 7 increases expression ISO Malathion results in increased expression of BRD7 mRNA CTD PMID:18214912 NCBI chr19:19,672,780...19,701,484
Ensembl chr19:19,672,856...19,701,484
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Malathion results in decreased expression of BUB1 mRNA CTD PMID:16079077 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA] CTD PMID:28385489 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Malathion results in increased activity of CASP3 protein
Malathion results in increased activity of and results in increased cleavage of CASP3 protein; Metoclopramide inhibits the reaction [Malathion results in increased activity of and results in increased cleavage of CASP3 protein]
Malathion results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]
Malathion results in increased expression of CASP3 mRNA
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]
CTD PMID:12505448, PMID:19815060, PMID:21628957, PMID:29027213, PMID:30769050 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO Malathion results in increased activity of CASP8 protein CTD PMID:12505448 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
multiple interactions
increases expression
ISO
EXP
Malathion results in increased activity of CASP9 protein
Malathion results in increased cleavage of CASP9 protein
Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]
CTD PMID:12505448, PMID:21628957, PMID:30769050 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
increases activity
EXP
ISO
[Dimethoate co-treated with Malathion] results in increased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; Pentoxifylline inhibits the reaction [Malathion results in increased activity of CAT protein]; Taurine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
Malathion results in decreased expression of CAT protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]
[Malathion co-treated with 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide] results in increased activity of CAT protein; [Malathion co-treated with pralidoxime] results in increased activity of CAT protein; lavender oil inhibits the reaction [Malathion results in decreased expression of CAT protein]
CTD PMID:11834209, PMID:18655177, PMID:19429256, PMID:20194575, PMID:21628957, PMID:21723318, PMID:24810974, PMID:25180440, PMID:28987951, PMID:30409133, PMID:30769050 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cck cholecystokinin increases expression EXP Malathion results in increased expression of CCK mRNA CTD PMID:19784758 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Malathion results in decreased expression of CCNA2 protein CTD PMID:30769050 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Malathion results in decreased expression of CCNB1 protein CTD PMID:30769050 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Malathion results in decreased expression of CCNE1 protein CTD PMID:30769050 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Malathion results in decreased expression of CDC20 mRNA CTD PMID:18214805 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Malathion results in decreased expression of CDK2 protein CTD PMID:30769050 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cenpf centromere protein F decreases expression ISO Malathion results in decreased expression of CENPF mRNA CTD PMID:16079077 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Malathion results in increased expression of CES1 mRNA CTD PMID:17311802 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cldn5 claudin 5 multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of CLDN5 protein
Malathion results in decreased expression of CLDN5 protein
CTD PMID:20970449 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
decreases expression
EXP caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:20233601, PMID:25404496 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression EXP Malathion results in decreased expression of CRISPLD2 mRNA CTD PMID:19784758 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Ctsd cathepsin D increases expression ISO Malathion results in increased expression of CTSD protein CTD PMID:8812242 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO Malathion results in decreased expression of CYP11A1 mRNA
lavender oil inhibits the reaction [Malathion results in decreased expression of CYP11A1 mRNA]
CTD PMID:30409133 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA CTD PMID:23954766 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression
ISO CYP1A2 protein affects the metabolism of Malathion
Malathion results in increased expression of CYP1A2 mRNA
CTD PMID:15557345, PMID:22310298 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
multiple interactions
increases expression
decreases activity
ISO CYP2B6 protein affects the metabolism of Malathion
Malathion promotes the reaction [isomalathion results in increased expression of CYP2B6 mRNA]
Malathion results in increased expression of CYP2B6 mRNA
Malathion results in decreased activity of CYP2B6 protein
CTD PMID:15557345, PMID:22310298, PMID:24333466 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
ISO Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
Malathion results in decreased activity of CYP2E1 protein
CTD PMID:22634058 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing ISO CYP3A5 protein affects the metabolism of Malathion CTD PMID:17110060 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 increases expression ISO Malathion results in increased expression of DVL1 mRNA CTD PMID:18204794 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Ehbp1 EH domain binding protein 1 increases response to substance ISO EHBP1 gene SNP results in increased susceptibility to Malathion CTD PMID:23593118 NCBI chr14:106,871,426...107,160,224
Ensembl chr14:106,871,430...107,160,334
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Malathion results in decreased expression of EPHX1 mRNA CTD PMID:17311802 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Esr1 estrogen receptor 1 decreases activity ISO Malathion results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv6 ETS variant transcription factor 6 increases expression ISO Malathion results in increased expression of ETV6 mRNA mutant form CTD PMID:28624474 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases activity
EXP [Malathion co-treated with Carbaryl] results in increased activity of G6PD protein; Plant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]
Malathion results in increased activity of G6PD protein
CTD PMID:27214522 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gk glycerol kinase multiple interactions
increases activity
EXP Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein] CTD PMID:25449180 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gk2 glycerol kinase 2 decreases expression EXP Malathion results in decreased expression of GK2 mRNA CTD PMID:25449180 NCBI chr14:13,751,284...13,753,136
Ensembl chr14:13,751,231...13,753,160
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP Malathion results in increased activity of GPT protein CTD PMID:25180440 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression EXP Malathion results in increased expression of GSK3B mRNA CTD PMID:25449180 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[Hexachlorocyclohexane co-treated with Malathion] results in decreased activity of GSR protein
zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD PMID:16718366, PMID:19429256 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases expression
ISO [Malathion co-treated with Estrogens] results in increased expression of HRAS mRNA
Malathion results in increased expression of HRAS mRNA; Malathion results in increased expression of HRAS protein
CTD PMID:18204794, PMID:19787260 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions
decreases expression
ISO lavender oil inhibits the reaction [Malathion results in decreased expression of HSD17B3 mRNA] CTD PMID:30409133 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases expression ISO Malathion results in increased expression of HSPB2 protein CTD PMID:19607909 NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Malathion inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma decreases expression
increases expression
multiple interactions
EXP Malathion results in decreased expression of IFNG protein
Malathion results in increased expression of IFNG mRNA
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]
CTD PMID:19145326, PMID:24810974, PMID:25180440, PMID:28987951 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IL1B mRNA] CTD PMID:24810974, PMID:25180440, PMID:28987951 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression EXP Malathion results in decreased expression of IL1R2 mRNA CTD PMID:19784758 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA] CTD PMID:24810974, PMID:25180440 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kmt2a lysine methyltransferase 2A increases mutagenesis
increases expression
ISO Malathion results in increased mutagenesis of KMT2A gene
Malathion results in increased expression of KMT2A mRNA mutant form
CTD PMID:28624474 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Lat linker for activation of T cells increases expression EXP Malathion results in increased expression of LAT mRNA CTD PMID:19784758 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions
increases expression
ISO [Malathion co-treated with Estrogens] results in increased expression of MCM2 mRNA
Malathion results in increased expression of MCM2 mRNA
CTD PMID:18204794 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein] CTD PMID:24810974, PMID:25180440 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Malathion results in decreased expression of COX1 mRNA CTD PMID:18214912 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Malathion results in decreased expression of COX3 mRNA CTD PMID:18214912 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Nefh neurofilament heavy affects expression
increases expression
EXP Malathion affects the expression of NEFH mRNA
Malathion results in increased expression of NEFH mRNA
CTD PMID:22954530, PMID:28385489 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO Malathion results in increased activity of NFE2L2 protein CTD PMID:30114225, PMID:30203046 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Malathion results in increased expression of NOS2 mRNA CTD PMID:20233601 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Malathion results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
increases activity
ISO Malathion results in increased expression of NR1I3 mRNA
Malathion results in increased activity of NR1I3 protein
CTD PMID:22310298, PMID:28927721, PMID:30203046 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Ocln occludin multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of OCLN protein
Malathion results in decreased expression of OCLN protein
CTD PMID:20970449 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G P2rx1 purinergic receptor P2X 1 increases expression EXP Malathion results in increased expression of P2RX1 mRNA CTD PMID:19784758 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Malathion results in increased cleavage of PARP1 protein
Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein]
CTD PMID:29027213 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA] CTD PMID:25449180 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Malathion results in decreased expression of PLAT mRNA CTD PMID:16079077 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Malathion results in decreased expression of PPARA mRNA CTD PMID:25689681 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pygl glycogen phosphorylase L multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA] CTD PMID:25449180 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP Malathion results in increased expression of RELA mRNA
Taurine inhibits the reaction [Malathion results in increased expression of RELA mRNA]
CTD PMID:28987951 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rfc3 replication factor C subunit 3 decreases expression ISO Malathion results in decreased expression of RFC3 mRNA CTD PMID:16079077 NCBI chr12:1,460,581...1,471,344
Ensembl chr12:1,460,538...1,471,357
JBrowse link
G Rnase6 ribonuclease A family member k6 increases expression EXP Malathion results in increased expression of RNASE6 mRNA CTD PMID:19784758 NCBI chr15:28,080,307...28,084,269
Ensembl chr15:28,081,004...28,081,465
JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression ISO Malathion results in increased expression of RUNX1 mRNA mutant form CTD PMID:28624474 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Malathion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Sod1 superoxide dismutase 1 increases activity
decreases expression
multiple interactions
EXP
ISO
Malathion results in increased activity of SOD1 protein
Malathion results in decreased expression of SOD1 protein
lavender oil inhibits the reaction [Malathion results in decreased expression of SOD1 protein]
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein]
CTD PMID:20194575, PMID:30409133 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; Malathion results in increased expression of and results in increased activity of SOD2 protein
lavender oil inhibits the reaction [Malathion results in decreased expression of SOD2 protein]
CTD PMID:20194575, PMID:30409133 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression EXP Malathion results in decreased expression of SRSF5 mRNA CTD PMID:19784758 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 increases expression EXP Malathion results in increased expression of ST8SIA1 mRNA CTD PMID:19784758 NCBI chr 4:177,065,266...177,195,942
Ensembl chr 4:177,065,168...177,196,180
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
ISO Malathion results in decreased expression of STAR mRNA
lavender oil inhibits the reaction [Malathion results in decreased expression of STAR mRNA]
CTD PMID:30409133 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Malathion results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression EXP Malathion results in decreased expression of TIMP3 mRNA CTD PMID:19784758 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of TJP1 protein
Malathion results in decreased expression of TJP1 protein
CTD PMID:20970449 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tjp2 tight junction protein 2 multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of TJP2 protein
Malathion results in decreased expression of TJP2 protein
CTD PMID:20970449 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP Malathion results in increased expression of TNF mRNA
Taurine inhibits the reaction [Malathion results in increased expression of TNF mRNA]
CTD PMID:28987951 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO
EXP
Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]
Malathion results in increased expression of TRP53 protein
Malathion results in increased expression of TP53 mRNA; Malathion results in increased expression of TP53 protein
CTD PMID:12505448, PMID:12762645, PMID:18204794, PMID:19787260, PMID:21628957 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression
multiple interactions
ISO Malathion results in increased expression of TP53I3 mRNA
[Malathion co-treated with Estrogens] results in increased expression of TP53I3 mRNA
CTD PMID:18204794 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 increases expression EXP Malathion results in increased expression of TRPC1 mRNA; Malathion results in increased expression of TRPC1 protein CTD PMID:22674931 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 increases expression EXP Malathion results in increased expression of TRPC4 mRNA; Malathion results in increased expression of TRPC4 protein CTD PMID:22674931 NCBI chr 2:143,433,102...143,605,757
Ensembl chr 2:143,475,323...143,604,972
JBrowse link
G Tyms thymidylate synthetase decreases expression ISO Malathion results in decreased expression of TYMS mRNA CTD PMID:16079077 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
permethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression ISO Permethrin results in increased expression of AACS mRNA CTD PMID:30629241 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Abat 4-aminobutyrate aminotransferase affects activity EXP Permethrin affects the activity of ABAT protein CTD PMID:15189238 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Permethrin results in increased expression of ABCC4 mRNA CTD PMID:30629241 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity
increases expression
ISO Permethrin results in decreased activity of ABCG2 protein
Permethrin results in increased expression of ABCG2 mRNA
CTD PMID:23169446, PMID:30629241 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd1 abhydrolase domain containing 1 increases expression ISO Permethrin results in increased expression of ABHD1 mRNA CTD PMID:30629241 NCBI chr 6:26,787,807...26,792,795
Ensembl chr 6:26,784,058...26,792,808
JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase increases expression ISO Permethrin results in increased expression of ABHD6 mRNA CTD PMID:30629241 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression ISO Permethrin results in increased expression of ACAA1A mRNA CTD PMID:30629241 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
increases activity
EXP [DEET co-treated with Permethrin] results in decreased activity of ACHE protein; [DEET co-treated with Permethrin] results in increased activity of ACHE protein; [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in increased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in decreased activity of ACHE protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of ACHE protein
Permethrin results in decreased activity of ACHE protein
Permethrin results in increased activity of ACHE protein
CTD PMID:7595515, PMID:11248143, PMID:14713564, PMID:14751452 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO Permethrin results in increased expression of ACOT1 mRNA CTD PMID:30629241 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Permethrin results in increased expression of ACOT2 mRNA CTD PMID:30629241 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO Permethrin results in increased expression of ACOT3 mRNA CTD PMID:30629241 NCBI chr 6:107,531,508...107,537,446
Ensembl chr 6:107,531,528...107,536,789
JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression ISO Permethrin results in increased expression of ACOT4 mRNA CTD PMID:30629241 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Permethrin results in increased expression of ACOX1 mRNA CTD PMID:30629241 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression ISO Permethrin results in increased expression of ACSL1 mRNA CTD PMID:30629241 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acyp2 acylphosphatase 2 increases expression ISO Permethrin results in increased expression of ACYP2 mRNA CTD PMID:30629241 NCBI chr14:114,891,245...115,052,497
Ensembl chr14:114,891,246...115,052,450
JBrowse link
G Adcy1 adenylate cyclase 1 decreases activity EXP Permethrin results in decreased activity of ADCY1 protein CTD PMID:2957417 NCBI chr14:87,311,970...87,429,880
Ensembl chr14:87,312,203...87,421,659
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AGER protein CTD PMID:32832901 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AIF1 protein CTD PMID:27984134 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Ak1 adenylate kinase 1 increases activity ISO Permethrin results in increased activity of AK1 protein CTD PMID:19326768 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Permethrin inhibits the reaction [INS1 protein results in increased expression of and results in increased phosphorylation of AKT1 protein]; Permethrin results in decreased expression of and results in increased phosphorylation of AKT1 protein CTD PMID:24911977 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin decreases expression EXP Permethrin results in decreased expression of ALB protein CTD PMID:21616133 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression ISO Permethrin results in increased expression of ALDH3A2 mRNA CTD PMID:30629241 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Permethrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA]; Permethrin inhibits the reaction [Progesterone results in increased activity of ALPL protein] CTD PMID:16326432, PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ALS2 mRNA CTD PMID:28659758 NCBI chr 9:65,961,361...66,034,396
Ensembl chr 9:65,961,346...66,033,871
JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Permethrin results in increased expression of AOX1 mRNA CTD PMID:30629241 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of APC mRNA CTD PMID:28659758 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression ISO Permethrin results in decreased expression of APOA4 mRNA CTD PMID:30629241 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoe apolipoprotein E multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of APOE mRNA CTD PMID:28659758 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ar androgen receptor multiple interactions
decreases activity
ISO [Dihydrotestosterone co-treated with Permethrin] results in decreased expression of AR mRNA; Permethrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Permethrin results in decreased activity of [Dihydrotestosterone results in increased activity of AR protein]
Permethrin results in decreased activity of AR protein
CTD PMID:16621434, PMID:16857237, PMID:17980950, PMID:20410157, PMID:28803809 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression ISO Permethrin results in increased expression of ARPP19 mRNA CTD PMID:30629241 NCBI chr 8:81,949,577...81,972,054
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP5F1A mRNA CTD PMID:28659758 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP5F1B mRNA CTD PMID:28659758 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP6AP1 mRNA CTD PMID:28659758 NCBI chr  X:156,407,973...156,415,053
Ensembl chr  X:156,407,937...156,415,145
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ATP6V0A2 mRNA CTD PMID:28659758 NCBI chr12:37,368,321...37,398,233
Ensembl chr12:37,363,906...37,425,596
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 decreases expression ISO Permethrin results in decreased expression of ATP6V0D2 mRNA CTD PMID:30629241 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression ISO Permethrin results in decreased expression of AVPR1A mRNA CTD PMID:30629241 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of BAX protein CTD PMID:12587291 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of BCHE protein CTD PMID:14751452 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Permethrin results in increased expression of BCL2 mRNA mutant form CTD PMID:28624474 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of BCL6 mRNA CTD PMID:28659758 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
decreases expression
ISO
EXP
[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA]; [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein]; Permethrin inhibits the reaction [Potassium results in increased expression of BDNF mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
Permethrin results in increased expression of BDNF mRNA
Permethrin results in decreased expression of BDNF mRNA
CTD PMID:11082455, PMID:12111003, PMID:15527870, PMID:19017407, PMID:32832901 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bhlhb9 basic helix-loop-helix family member B9 increases expression ISO Permethrin results in increased expression of BHLHB9 mRNA CTD PMID:30629241 NCBI chr  X:106,359,981...106,393,457
Ensembl chr  X:106,390,759...106,393,459
JBrowse link
G Cabp5 calcium binding protein 5 affects response to substance ISO CABP5 gene SNP affects the susceptibility to Permethrin CTD PMID:25622337 NCBI chr 1:75,693,216...75,706,069
Ensembl chr 1:75,693,232...75,706,069
JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase IG increases expression EXP Permethrin results in increased expression of CAMK1G mRNA alternative form CTD PMID:20143453 NCBI chr13:112,075,689...112,099,472
Ensembl chr13:112,075,690...112,099,336
JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Permethrin results in increased expression of CAR2 mRNA CTD PMID:30629241 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Cat catalase increases activity
affects binding
multiple interactions
EXP
ISO
Permethrin results in increased activity of CAT protein
Permethrin binds to CAT protein
[Propoxur co-treated with Permethrin] results in increased activity of CAT protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CAT mRNA
CTD PMID:12965126, PMID:28456543, PMID:28659758, PMID:32278787 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO Permethrin results in increased expression of CBR3 mRNA CTD PMID:30629241 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CCL2 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CCL2 mRNA] CTD PMID:29751049 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CCL3 protein CTD PMID:28659758 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP Permethrin results in increased expression of CCL5 protein CTD PMID:21616133 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccs copper chaperone for superoxide dismutase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CCS mRNA CTD PMID:28659758 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd36 CD36 molecule increases expression ISO Permethrin results in increased expression of CD36 mRNA CTD PMID:30629241 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CD68 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CD68 mRNA] CTD PMID:29751049 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Permethrin results in increased expression of CEBPA mRNA CTD PMID:24911977 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cela1 chymotrypsin like elastase 1 decreases expression ISO Permethrin results in decreased expression of CELA1 mRNA CTD PMID:30629241 NCBI chr 7:142,305,337...142,318,621
Ensembl chr 7:142,305,338...142,318,620
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 increases expression ISO Permethrin results in increased expression of CELF2 mRNA CTD PMID:30629241 NCBI chr17:75,259,269...75,660,154
Ensembl chr17:75,352,389...75,654,951
JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis
affects hydrolysis
ISO
EXP
CES1 protein results in increased hydrolysis of Permethrin
CES1 protein affects the hydrolysis of Permethrin
CTD PMID:16359636, PMID:16387282, PMID:18983829 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H affects hydrolysis
increases hydrolysis
increases metabolic processing
ISO
EXP
CES2 protein affects the hydrolysis of Permethrin
CES2 protein results in increased hydrolysis of Permethrin
CES2 protein results in increased metabolism of Permethrin
CTD PMID:16359636, PMID:16387282, PMID:18983829, PMID:19249324 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of CHAT protein CTD PMID:11248143 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chpt1 choline phosphotransferase 1 increases expression ISO Permethrin results in increased expression of CHPT1 mRNA CTD PMID:30629241 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] promotes the reaction [AFDX 384 binds to CHRM2 protein]; [Pyridostigmine Bromide co-treated with Permethrin] promotes the reaction [AFDX 384 binds to CHRM2 protein]; Permethrin promotes the reaction [AFDX 384 binds to CHRM2 protein] CTD PMID:11248143, PMID:14751452 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit increases expression ISO Permethrin results in increased expression of CHRNA2 mRNA CTD PMID:30629241 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
JBrowse link
G Cldn2 claudin 2 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of CLDN2 protein CTD PMID:29751049 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cldn5 claudin 5 multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of CLDN5 mRNA; [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of CLDN5 protein CTD PMID:32832901 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Clstn3 calsyntenin 3 increases expression ISO Permethrin results in increased expression of CLSTN3 mRNA CTD PMID:30629241 NCBI chr 4:157,044,736...157,078,013
Ensembl chr 4:157,043,925...157,078,130
JBrowse link
G Comt catechol-O-methyltransferase decreases expression ISO Permethrin results in decreased expression of COMT mRNA CTD PMID:30629241 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 increases expression EXP Permethrin results in increased expression of COPG2 mRNA CTD PMID:19017407 NCBI chr 4:58,064,394...58,195,242
Ensembl chr 4:58,064,833...58,195,143
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX5B mRNA CTD PMID:28659758 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX6A1 mRNA CTD PMID:28659758 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of COX7A2L mRNA CTD PMID:28659758 NCBI chr 6:6,695,807...6,709,790
Ensembl chr 6:6,695,827...6,709,783
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO Permethrin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA] CTD PMID:30738135 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO Permethrin results in decreased expression of CPT1B mRNA CTD PMID:24911977 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Crat carnitine O-acetyltransferase increases expression ISO Permethrin results in increased expression of CRAT mRNA CTD PMID:30629241 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Crh corticotropin releasing hormone increases expression EXP Permethrin results in increased expression of CRH mRNA CTD PMID:19017407 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Csad cysteine sulfinic acid decarboxylase increases expression ISO Permethrin results in increased expression of CSAD mRNA CTD PMID:30629241 NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CSF2 mRNA CTD PMID:28659758 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Permethrin results in increased expression of CSF2RB mRNA CTD PMID:30629241 NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
JBrowse link
G Ctsb cathepsin B multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CTSB mRNA CTD PMID:28659758 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CXCL10 protein CTD PMID:28659758 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP Permethrin results in increased expression of CXCL12 mRNA CTD PMID:19017407 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CYC1 mRNA CTD PMID:28659758 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Cygb cytoglobin multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of CYGB mRNA CTD PMID:28659758 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO Permethrin analog results in decreased expression of CYP11A1 mRNA; Permethrin results in decreased expression of CYP11A1 mRNA; Permethrin results in decreased expression of CYP11A1 protein CTD PMID:17463061, PMID:18455858, PMID:21745691 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
multiple interactions
ISO
EXP
Permethrin results in increased expression of CYP1A1 mRNA; Permethrin results in increased expression of CYP1A1 protein
Permethrin results in decreased activity of CYP1A1 protein
[Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA
CTD PMID:11377398, PMID:19326768, PMID:20009351, PMID:21784029 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Permethrin results in increased expression of CYP1A2 mRNA; Permethrin results in increased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
EXP
ISO
[Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP2B1 mRNA; EGF protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA]; GH1 protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA]; Piperonyl Butoxide inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA]
Permethrin results in increased expression of CYP2B10 mRNA
CTD PMID:11377398, PMID:14722249, PMID:30629241 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects activity
multiple interactions
increases expression
ISO Permethrin affects the activity of CYP2B6 protein
[Permethrin co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA
Permethrin results in increased expression of CYP2B6 mRNA
CTD PMID:19326768, PMID:21924250, PMID:31312845 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases metabolic processing ISO CYP2C19 protein results in increased metabolism of Permethrin CTD PMID:24548679 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions
EXP Permethrin results in increased expression of CYP3A23-3A1 mRNA
EGF protein inhibits the reaction [Permethrin results in increased expression of CYP3A23-3A1 mRNA]
CTD PMID:11377398, PMID:29477483 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Permethrin results in increased expression of CYP3A5 mRNA CTD PMID:19326768 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO Permethrin results in decreased expression of CYP4F14 mRNA CTD PMID:30629241 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Ddc dopa decarboxylase decreases expression EXP Permethrin results in decreased expression of DDC mRNA CTD PMID:19017407 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Permethrin inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 mRNA] CTD PMID:30738135 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression ISO Permethrin results in increased expression of DECR1 mRNA CTD PMID:30629241 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions
increases expression
EXP
ISO
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DHCR24 mRNA
Permethrin results in increased expression of DHCR24 mRNA
CTD PMID:28659758, PMID:30629241 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dnm2 dynamin 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DNM2 mRNA CTD PMID:28659758 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Duox2 dual oxidase 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DUOX2 mRNA CTD PMID:28659758 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression EXP Permethrin results in increased expression of DUSP6 mRNA CTD PMID:19017407 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 increases expression EXP Permethrin results in increased expression of DYNC1I1 mRNA CTD PMID:19017407 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G Egf epidermal growth factor multiple interactions EXP EGF protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA]; EGF protein inhibits the reaction [Permethrin results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:11377398, PMID:14722249 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egr1 early growth response 1 increases expression EXP Permethrin results in increased expression of EGR1 mRNA CTD PMID:19017407 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO Permethrin results in increased expression of EHHADH mRNA CTD PMID:30629241 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Enho energy homeostasis associated decreases expression ISO Permethrin results in decreased expression of ENHO mRNA CTD PMID:30629241 NCBI chr 5:58,018,039...58,019,836
Ensembl chr 5:58,018,039...58,019,836
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression ISO Permethrin results in increased expression of ENTPD5 mRNA CTD PMID:30629241 NCBI chr 6:108,087,677...108,123,811
Ensembl chr 6:108,087,418...108,120,579
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Permethrin results in increased expression of EPHX1 mRNA CTD PMID:30629241 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases activity ISO Permethrin results in increased activity of ERBB2 protein CTD PMID:11222871 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ERCC6 mRNA CTD PMID:28659758 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
decreases expression
affects binding
increases activity
decreases activity
ISO
EXP
Permethrin metabolite binds to and results in increased activity of ESR1 protein
[Permethrin co-treated with Estradiol] results in decreased expression of ESR1
Permethrin results in increased expression of ESR1 mRNA
Permethrin metabolite results in increased expression of ESR1 mRNA
Permethrin results in decreased expression of ESR1 mRNA
Permethrin binds to ESR1 protein; Permethrin metabolite binds to ESR1 protein
Permethrin results in increased activity of ESR1 protein
Permethrin results in decreased activity of ESR1 protein
CTD PMID:12396874, PMID:15064155, PMID:16395479, PMID:20397420, PMID:20410157, PMID:20574910, PMID:24388911, PMID:25048945, PMID:32278787 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv6 ETS variant transcription factor 6 increases expression
increases mutagenesis
ISO Permethrin results in increased expression of ETV6 mRNA mutant form
Permethrin results in increased mutagenesis of ETV6 gene
CTD PMID:28624474 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Permethrin results in increased expression of FABP4 mRNA CTD PMID:24911977 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
decreases expression
ISO Palmitic Acid inhibits the reaction [Permethrin results in decreased expression of FAS mRNA] CTD PMID:30738135 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fasn fatty acid synthase increases expression ISO Permethrin results in increased expression of FASN mRNA CTD PMID:24911977, PMID:30629241 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo22 F-box protein 22 increases expression EXP Permethrin results in increased expression of FBXO22 mRNA CTD PMID:19017407 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of FGF2 protein CTD PMID:28659758 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 increases expression ISO Permethrin results in increased expression of FITM2 mRNA CTD PMID:30629241 NCBI chr 3:159,856,994...159,863,506
Ensembl chr 3:159,856,994...159,863,506
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of FMO2 mRNA CTD PMID:28659758 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 decreases expression ISO Permethrin results in decreased expression of FMO3 mRNA CTD PMID:30629241 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Fn3k fructosamine 3 kinase decreases expression ISO Permethrin results in decreased expression of FN3K mRNA CTD PMID:30629241 NCBI chr10:110,626,462...110,642,262
Ensembl chr10:110,631,494...110,642,260
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO
EXP
[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of FOS mRNA]; Permethrin inhibits the reaction [Potassium results in increased expression of FOS mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA]
Permethrin results in increased expression of FOS mRNA; Permethrin results in increased expression of FOS protein
Permethrin results in decreased expression of FOS mRNA; Permethrin results in decreased expression of FOS protein
CTD PMID:8856738, PMID:11082455, PMID:12111003, PMID:15527870, PMID:19017407 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxq1 forkhead box Q1 decreases expression ISO Permethrin results in decreased expression of FOXQ1 mRNA CTD PMID:30629241 NCBI chr17:34,224,308...34,226,941
Ensembl chr17:34,224,818...34,226,453
JBrowse link
G Gale UDP-galactose-4-epimerase increases expression ISO Permethrin results in increased expression of GALE mRNA CTD PMID:30629241 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GCLC mRNA CTD PMID:28659758 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions
ISO
EXP
Permethrin results in increased expression of GFAP protein
[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of GFAP protein
[DEET co-treated with Permethrin] results in increased expression of GFAP protein
CTD PMID:11681848, PMID:14555407, PMID:27984134 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP Permethrin results in increased activity of GGT1 protein CTD PMID:2902710 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA] CTD PMID:14722249 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Glyr1 glyoxylate reductase 1 homolog multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GLYR1 mRNA CTD PMID:28659758 NCBI chr10:10,725,830...10,759,471
Ensembl chr10:10,725,819...10,761,279
JBrowse link
G Gna14 G protein subunit alpha 14 increases expression EXP Permethrin results in increased expression of GNA14 mRNA CTD PMID:19017407 NCBI chr 1:235,165,775...235,347,986
Ensembl chr 1:235,166,718...235,347,937
JBrowse link
G Golm2 golgi membrane protein 2 increases expression ISO Permethrin results in increased expression of GOLM2 mRNA CTD PMID:30629241 NCBI chr 3:113,818,649...113,887,550
Ensembl chr 3:113,818,872...113,887,495
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression EXP Permethrin results in decreased expression of GOT2 protein CTD PMID:26631339 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases expression EXP Permethrin results in increased expression of GPD1 mRNA CTD PMID:19017407 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C decreases expression ISO Permethrin results in decreased expression of GPRC5C mRNA CTD PMID:30629241 NCBI chr10:103,395,222...103,417,360
Ensembl chr10:103,395,511...103,417,358
JBrowse link
G Gprin3 GPRIN family member 3 decreases expression ISO Permethrin results in decreased expression of GPRIN3 mRNA CTD PMID:30629241 NCBI chr 4:89,690,678...89,778,302
Ensembl chr 4:89,693,280...89,695,928
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases activity EXP Permethrin results in decreased activity of GPX1 protein CTD PMID:12965126 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX3 mRNA CTD PMID:28659758 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX4 mRNA CTD PMID:28659758 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gpx6 glutathione peroxidase 6 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX6 mRNA CTD PMID:28659758 NCBI chr17:45,439,268...45,446,952
Ensembl chr17:45,439,268...45,446,907
JBrowse link
G Gpx7 glutathione peroxidase 7 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GPX7 mRNA CTD PMID:28659758 NCBI chr 5:128,001,766...128,009,610
Ensembl chr 5:128,001,761...128,009,735
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
[Hexachlorocyclohexane co-treated with Permethrin] results in decreased activity of GSR protein
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GSR mRNA
CTD PMID:16718366, PMID:28659758 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO Permethrin results in increased expression of GSTA2 mRNA CTD PMID:30629241 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO Permethrin results in increased expression of GSTA2 mRNA CTD PMID:30629241 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GSTK1 mRNA CTD PMID:28659758 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Permethrin results in increased expression of GSTM1 mRNA CTD PMID:30629241 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression ISO Permethrin results in increased expression of GSTM4 mRNA CTD PMID:30629241 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO Permethrin results in increased expression of GSTM3 mRNA CTD PMID:30629241 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of GSTP1 mRNA CTD PMID:28659758 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [Permethrin results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of HMGB1 protein; [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of HMGB1 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of HMGB1 protein] CTD PMID:29751049, PMID:32832901 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Permethrin analog results in decreased expression of HMGCR mRNA CTD PMID:21745691 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Permethrin analog results in decreased expression of HMGCS1 mRNA CTD PMID:21745691 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of HMOX1 mRNA CTD PMID:28659758 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 decreases expression ISO Permethrin analog results in decreased expression of HSD17B13 mRNA CTD PMID:21745691 NCBI chr14:7,113,544...7,128,218
Ensembl chr14:7,113,544...7,128,218
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Permethrin analog results in decreased expression of HSD3B1 mRNA; Permethrin results in decreased expression of HSD3B2 mRNA CTD PMID:21745691, PMID:30629241
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression ISO Permethrin results in increased expression of HSDL2 mRNA CTD PMID:30629241 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Permethrin results in increased expression of HSPB1 mRNA CTD PMID:30629241 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Permethrin results in increased expression of HTATIP2 mRNA CTD PMID:30629241 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NARG2 mRNA CTD PMID:28659758 NCBI chr 8:75,625,147...75,666,959
Ensembl chr 8:75,625,174...75,666,866
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IDH1 mRNA CTD PMID:28659758 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO
EXP
IFNG protein affects the susceptibility to [Permethrin co-treated with Urocanic Acid]
Permethrin results in increased expression of IFNG protein
CTD PMID:14617103, PMID:21616133 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ift172 intraflagellar transport 172 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IFT172 mRNA CTD PMID:28659758 NCBI chr 6:26,390,686...26,485,459 JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression EXP Permethrin results in increased expression of IGFBP3 mRNA CTD PMID:19017407 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il10 interleukin 10 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in decreased expression of IL10 mRNA CTD PMID:28659758 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il15 interleukin 15 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL15 protein CTD PMID:28659758 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein] CTD PMID:32832901 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNA CTD PMID:28659758 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Permethrin results in increased expression of IL1B protein
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of and results in increased secretion of IL1B protein; [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of IL1B mRNA; [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL1B protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of and results in increased secretion of IL1B protein]; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of IL1B mRNA]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL1B protein]
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1B protein
CTD PMID:21616133, PMID:28659758, PMID:29751049, PMID:32832901 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases expression EXP Permethrin results in increased expression of IL2 protein CTD PMID:21616133 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in decreased expression of IL4 mRNA CTD PMID:28659758 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL5 protein CTD PMID:28659758 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
EXP
ISO
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL6 protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL6 mRNA
[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL6 protein; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL6 protein]
Permethrin results in decreased expression of IL6 mRNA
CTD PMID:28659758, PMID:29477483, PMID:32832901 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Permethrin results in decreased expression of IL6RA mRNA CTD PMID:30629241 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Permethrin co-treated with INS protein] results in increased phosphorylation of IRS1 protein; [Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein; [Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein; U 0126 inhibits the reaction [[Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:28866332 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [Permethrin co-treated with INS protein] results in increased phosphorylation of IRS1 protein CTD PMID:28866332 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Permethrin results in increased expression of JUN protein CTD PMID:8856738 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnk5 potassium two pore domain channel subfamily K member 5 decreases expression ISO Permethrin results in decreased expression of KCNK5 mRNA CTD PMID:30629241 NCBI chr15:4,554,603...4,597,000
Ensembl chr15:4,554,603...4,597,000
JBrowse link
G Klf10 Kruppel-like factor 10 affects response to substance ISO KLF10 gene SNP affects the susceptibility to Permethrin CTD PMID:25622337 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Kmt2a lysine methyltransferase 2A increases mutagenesis ISO Permethrin results in increased mutagenesis of KMT2A gene CTD PMID:12937054, PMID:28624474 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Lep leptin multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of LEP protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased secretion of LEP protein] CTD PMID:29751049 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of LHPP mRNA CTD PMID:28659758 NCBI chr 1:204,617,804...204,708,987
Ensembl chr 1:204,617,852...204,708,987
JBrowse link
G Lifr LIF receptor subunit alpha decreases expression ISO Permethrin results in decreased expression of LIFR mRNA CTD PMID:30629241 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G Limd2 LIM domain containing 2 decreases expression ISO Permethrin results in decreased expression of LIMD2 mRNA CTD PMID:30629241 NCBI chr10:94,350,789...94,353,301
Ensembl chr10:94,350,817...94,352,880
JBrowse link
G LOC100365958 Rdh2 protein-like increases expression ISO Permethrin results in increased expression of RDH16 mRNA CTD PMID:30629241 NCBI chr 7:71,065,077...71,074,128
Ensembl chr 7:70,980,422...71,072,689
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Permethrin results in increased expression of LPL mRNA CTD PMID:24911977, PMID:30629241 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
decreases expression
EXP [DEET co-treated with Permethrin] results in decreased expression of MAP2 protein
Permethrin results in decreased expression of MAP2 protein
CTD PMID:11681848 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MAPK1 mRNA
Permethrin results in increased phosphorylation of MAPK1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; 3,5-dihydroxyphenylglycine promotes the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; [Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein; bisindolylmaleimide I inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; Tetrodotoxin inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]
CTD PMID:28659758, PMID:28866332, PMID:30205134 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MAPK3 mRNA
Permethrin results in increased phosphorylation of MAPK3 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Permethrin results in increased phosphorylation of MAPK3 protein]; 3,5-dihydroxyphenylglycine promotes the reaction [Permethrin results in increased phosphorylation of MAPK3 protein]; [Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein; bisindolylmaleimide I inhibits the reaction [Permethrin results in increased phosphorylation of MAPK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Permethrin results in increased phosphorylation of MAPK3 protein]; Tetrodotoxin inhibits the reaction [Permethrin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [[Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]
CTD PMID:28659758, PMID:28866332, PMID:30205134 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mbp myelin basic protein decreases expression EXP Permethrin results in decreased expression of MBP protein CTD PMID:26631339 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression EXP Permethrin results in decreased expression of MDH2 protein CTD PMID:26631339 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Permethrin results in increased expression of ME1 mRNA CTD PMID:30629241 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO Permethrin promotes the reaction [MED1 protein binds to NR1I3 protein alternative form] CTD PMID:31312845 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Med10 mediator complex subunit 10 increases expression EXP Permethrin results in increased expression of MED10 mRNA CTD PMID:19017407 NCBI chr 1:36,107,249...36,118,887
Ensembl chr 1:36,107,232...36,112,993
JBrowse link
G Mgll monoglyceride lipase increases expression ISO Permethrin results in increased expression of MGLL mRNA CTD PMID:30629241 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase increases expression ISO Permethrin results in increased expression of MLKL mRNA CTD PMID:30629241 NCBI chr19:43,508,416...43,535,050
Ensembl chr19:43,506,976...43,528,851
JBrowse link
G Mpo myeloperoxidase increases activity
multiple interactions
EXP Permethrin results in increased activity of MPO protein
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MPO mRNA
CTD PMID:19772857, PMID:28659758 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nat8f1 N-acetyltransferase 8 (GCN5-related) family member 1 decreases expression ISO Permethrin results in decreased expression of NAT8F1 mRNA CTD PMID:30629241 NCBI chr 4:117,582,779...117,589,464
Ensembl chr 4:117,582,781...117,589,464
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Permethrin promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; Permethrin promotes the reaction [NCOA1 protein binds to NR1I3 protein]; Permethrin promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein] CTD PMID:21924250, PMID:31312845 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO Permethrin promotes the reaction [NCOA3 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFA11 mRNA CTD PMID:28659758 NCBI chr 9:10,334,104...10,338,163
Ensembl chr 9:10,334,090...10,338,216
JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFA8 mRNA CTD PMID:28659758 NCBI chr 3:15,362,888...15,379,386
Ensembl chr 3:15,362,824...15,379,381
JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFA9 mRNA CTD PMID:28659758 NCBI chr 4:159,371,263...159,399,636
Ensembl chr 4:159,371,259...159,399,634
JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFB3 mRNA CTD PMID:28659758 NCBI chr 9:65,478,496...65,488,708
Ensembl chr 9:65,478,496...65,488,702
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFB5 mRNA CTD PMID:28659758 NCBI chr 2:119,139,717...119,153,753
Ensembl chr 2:119,139,717...119,153,753
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFS6 mRNA CTD PMID:28659758 NCBI chr 2:26,471,173...26,471,587
Ensembl chr 2:26,471,173...26,471,584
JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFS7 mRNA CTD PMID:28659758 NCBI chr 7:12,318,776...12,326,403
Ensembl chr 7:12,318,757...12,326,392
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFS8 mRNA CTD PMID:28659758 NCBI chr 1:219,141,289...219,144,610
Ensembl chr 1:219,141,292...219,144,610
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NDUFV1 mRNA CTD PMID:28659758 NCBI chr 1:219,254,293...219,259,328
Ensembl chr 1:219,254,279...219,259,448
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
decreases expression
multiple interactions
EXP Permethrin results in increased expression of NFE2L2 mRNA
Permethrin results in decreased expression of NFE2L2 mRNA
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and affects the localization of NFE2L2 protein
CTD PMID:23566817, PMID:23806482, PMID:28659758, PMID:29477483 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfia nuclear factor I/A decreases expression ISO Permethrin results in decreased expression of NFIA mRNA CTD PMID:30629241 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NFKB1 mRNA CTD PMID:28659758 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ngf nerve growth factor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NGF mRNA CTD PMID:28659758 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of BDNF protein]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL6 protein] CTD PMID:32832901 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NQO1 mRNA CTD PMID:28659758 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Permethrin inhibits the reaction [Palmitic Acid results in increased expression of NR1H4 mRNA] CTD PMID:30738135 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
EXP
ISO
Permethrin results in increased activity of NR1I2 protein
Permethrin binds to and results in increased activity of NR1I2 protein
[Permethrin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Permethrin binds to and results in increased activity of NR1I2 protein
CTD PMID:16565514, PMID:19249324, PMID:21115097, PMID:22206814, PMID:31312845 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
affects binding
increases activity
multiple interactions
ISO Permethrin results in increased expression of NR1I3 mRNA
Permethrin binds to NR1I3 protein
Permethrin results in increased activity of NR1I3 protein
[Permethrin co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; Permethrin binds to and results in increased activity of NR1I3 protein alternative form; Permethrin inhibits the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased activity of NR1I3 protein]; Permethrin promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]; Permethrin promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; Permethrin promotes the reaction [NCOA1 protein binds to NR1I3 protein]; Permethrin promotes the reaction [NCOA3 protein binds to NR1I3 protein]; Permethrin promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
CTD PMID:16929008, PMID:21924250, PMID:26187274, PMID:28927721, PMID:31312845 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO Permethrin inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; Permethrin inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression
multiple interactions
affects expression
increases expression
EXP Permethrin results in decreased expression of NR4A2; Permethrin results in decreased expression of NR4A2 mRNA; Permethrin results in decreased expression of NR4A2 protein
Glutathione inhibits the reaction [Permethrin results in increased expression of NR4A2 mRNA]; Tocotrienols inhibits the reaction [Permethrin results in increased expression of NR4A2 mRNA]
Permethrin affects the expression of NR4A2 mRNA
Permethrin results in increased expression of NR4A2 mRNA; Permethrin results in increased expression of NR4A2 protein
CTD PMID:22056222, PMID:23174539, PMID:23566817, PMID:25048945, PMID:28943456, PMID:29051472 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Permethrin results in increased expression of NR4A3 mRNA CTD PMID:19017407 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of NUDT1 mRNA CTD PMID:28659758 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
JBrowse link
G Ocln occludin multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of OCLN protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of OCLN protein] CTD PMID:29751049 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Oxnad1 oxidoreductase NAD-binding domain containing 1 decreases expression ISO Permethrin results in decreased expression of OXNAD1 mRNA CTD PMID:30629241 NCBI chr16:8,207,223...8,236,292
Ensembl chr16:8,207,223...8,236,292
JBrowse link
G Pak1ip1 PAK1 interacting protein 1 increases expression EXP Permethrin results in increased expression of PAK1IP1 mRNA CTD PMID:19017407 NCBI chr17:21,579,987...21,591,064
Ensembl chr17:21,580,087...21,591,203
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PARK7 mRNA CTD PMID:28659758 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pctp phosphatidylcholine transfer protein increases expression ISO Permethrin results in increased expression of PCTP mRNA CTD PMID:30629241 NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO Permethrin inhibits the reaction [INS1 protein results in increased phosphorylation of PDK1 protein] CTD PMID:24911977 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression ISO Permethrin results in increased expression of PEX11A mRNA CTD PMID:30629241 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315
JBrowse link
G Pfkp phosphofructokinase, platelet multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA] CTD PMID:29751049 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Permethrin inhibits the reaction [Progesterone results in increased expression of PGR protein] CTD PMID:16326432 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO Permethrin results in decreased expression of PKLR mRNA CTD PMID:30629241 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression ISO Permethrin results in increased expression of PNPLA2 mRNA CTD PMID:24911977 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
G Polr2h RNA polymerase II, I and III subunit H increases expression EXP Permethrin results in increased expression of POLR2H mRNA CTD PMID:19017407 NCBI chr11:83,877,760...83,882,208
Ensembl chr11:83,878,006...83,882,117
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PPA1 mRNA CTD PMID:28659758 NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases activity
decreases response to substance
ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]
Permethrin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA]
Permethrin results in increased activity of PPARA protein
PPARA gene mutant form results in decreased susceptibility to Permethrin
CTD PMID:29751049, PMID:30629241, PMID:30738135 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO Permethrin results in increased expression of PPARG mRNA; Permethrin results in increased expression of PPARG protein
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of PPARG mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in decreased expression of PPARG mRNA]
CTD PMID:24911977, PMID:29751049 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression ISO Permethrin results in decreased expression of PPP1R3B mRNA CTD PMID:30629241 NCBI chr16:60,415,192...60,427,498
Ensembl chr16:60,415,229...60,427,474
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX1 mRNA CTD PMID:28659758 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX2 mRNA CTD PMID:28659758 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX5 mRNA CTD PMID:28659758 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRDX6 mRNA CTD PMID:28659758 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 affects response to substance ISO PREX1 gene SNP affects the susceptibility to Permethrin CTD PMID:25622337 NCBI chr 3:163,329,580...163,477,822
Ensembl chr 3:163,329,975...163,477,715
JBrowse link
G Prim2 DNA primase subunit 2 increases expression EXP Permethrin results in increased expression of PRIM2 mRNA CTD PMID:19017407 NCBI chr 9:38,535,435...38,745,058
Ensembl chr 9:38,536,920...38,745,099
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRKACA mRNA CTD PMID:28659758 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prnp prion protein multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PRNP mRNA CTD PMID:28659758 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PSMB5 mRNA CTD PMID:28659758 NCBI chr15:33,259,039...33,263,634
Ensembl chr15:33,259,043...33,263,659
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of PTGS1 mRNA CTD PMID:28659758 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression ISO Permethrin results in increased expression of RAB30 mRNA CTD PMID:30629241 NCBI chr 1:157,573,344...157,667,973
Ensembl chr 1:157,573,324...157,660,008
JBrowse link
G Rad51b RAD51 paralog B increases expression ISO Permethrin results in increased expression of RAD51B mRNA CTD PMID:30629241 NCBI chr 6:102,473,978...103,018,185
Ensembl chr 6:102,477,036...102,512,505
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO Permethrin results in increased expression of RARRES1 mRNA CTD PMID:30629241 NCBI chr 2:164,650,722...164,684,982
Ensembl chr 2:164,650,722...164,684,985
JBrowse link
G Rassf5 Ras association domain family member 5 increases expression EXP Permethrin results in increased expression of RASSF5 mRNA CTD PMID:19017407 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rcan2 regulator of calcineurin 2 increases expression ISO Permethrin results in increased expression of RCAN2 mRNA CTD PMID:30629241 NCBI chr 9:19,518,568...19,749,145
Ensembl chr 9:19,518,558...19,749,145
JBrowse link
G Rdh5 retinol dehydrogenase 5 decreases expression ISO Permethrin results in decreased expression of RDH5 mRNA CTD PMID:30629241 NCBI chr 7:3,335,681...3,342,573
Ensembl chr 7:3,335,742...3,342,491
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects expression
increases expression
EXP Permethrin affects the expression of RELA protein
Permethrin results in increased expression of RELA mRNA
CTD PMID:23566817 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retsat retinol saturase increases expression ISO Permethrin results in increased expression of RETSAT mRNA CTD PMID:30629241 NCBI chr 4:100,465,365...100,474,128
Ensembl chr 4:100,465,170...100,474,301
JBrowse link
G RGD1307595 similar to RIKEN cDNA 1700018B24 increases expression EXP Permethrin results in increased expression of RGD1307595 mRNA CTD PMID:19017407 NCBI chr 2:138,194,136...138,197,442
Ensembl chr 2:138,194,136...138,197,442
JBrowse link
G Rimbp2 RIMS binding protein 2 increases expression EXP Permethrin results in increased expression of RIMBP2 mRNA CTD PMID:19017407 NCBI chr12:31,393,229...31,605,567
Ensembl chr12:31,530,699...31,620,760
JBrowse link
G Runx1 RUNX family transcription factor 1 increases mutagenesis
increases expression
ISO Permethrin results in increased mutagenesis of RUNX1 gene
Permethrin results in increased expression of RUNX1 mRNA mutant form
CTD PMID:28624474 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G S100g S100 calcium binding protein G increases expression
multiple interactions
EXP Permethrin results in increased expression of S100G mRNA
[Permethrin co-treated with Estradiol] results in increased expression of S100G mRNA
CTD PMID:15599112 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SCD1 mRNA CTD PMID:28659758 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
increases expression
EXP Permethrin affects the reaction [SCN10A protein results in increased transport of Sodium]
Permethrin results in increased expression of SCN10A protein
CTD PMID:16051293, PMID:24732443 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin co-treated with Chlorpyrifos] results in increased activity of SCN11A protein CTD PMID:29803855 NCBI chr 8:128,450,793...128,527,510
Ensembl chr 8:128,450,801...128,521,109
JBrowse link
G Sdc4 syndecan 4 decreases expression ISO Permethrin results in decreased expression of SDC4 mRNA CTD PMID:30629241 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SDHB mRNA CTD PMID:28659758 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Sdr9c7 short chain dehydrogenase/reductase family 9C, member 7 decreases expression ISO Permethrin results in decreased expression of SDR9C7 mRNA CTD PMID:30629241 NCBI chr 7:71,152,366...71,169,510
Ensembl chr 7:71,157,664...71,170,511
JBrowse link
G Selenop selenoprotein P multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SELENOP mRNA CTD PMID:28659758 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Serinc2 serine incorporator 2 increases expression ISO Permethrin results in increased expression of SERINC2 mRNA CTD PMID:30629241 NCBI chr 5:148,470,060...148,492,232
Ensembl chr 5:148,470,061...148,492,232
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression ISO Permethrin results in increased expression of SLC22A5 mRNA CTD PMID:30629241 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc25a10 solute carrier family 25 member 10 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SLC25A10 mRNA CTD PMID:28659758 NCBI chr10:109,665,682...109,674,782
Ensembl chr10:109,665,682...109,673,143
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SLC25A20 mRNA CTD PMID:28659758 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc27a1 solute carrier family 27 member 1 decreases expression EXP Permethrin results in decreased expression of SLC27A1 protein CTD PMID:26631339 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA] CTD PMID:29751049 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA] CTD PMID:29751049 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc38a1 solute carrier family 38, member 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SLC38A1 mRNA CTD PMID:28659758 NCBI chr 7:137,970,555...138,040,098
Ensembl chr 7:137,975,549...138,039,984
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression EXP Permethrin results in decreased expression of SLC40A1 mRNA CTD PMID:19017407 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc48a1 solute carrier family 48 member 1 increases expression ISO Permethrin results in increased expression of SLC48A1 mRNA CTD PMID:30629241 NCBI chr 7:139,271,698...139,279,499
Ensembl chr 7:139,271,698...139,279,499
JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects activity
increases expression
decreases expression
multiple interactions
ISO Permethrin affects the activity of SLC6A3 protein
Permethrin results in increased expression of SLC6A3 protein
Permethrin results in decreased expression of SLC6A3 protein
Permethrin inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]
CTD PMID:12428726, PMID:14555407, PMID:14575646, PMID:16005927 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Snca synuclein alpha increases expression ISO Permethrin results in increased expression of SNCA protein CTD PMID:14575646 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod1 superoxide dismutase 1 increases activity EXP Permethrin results in increased activity of SOD1 protein CTD PMID:12965126 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SOD2 mRNA
Permethrin results in increased expression of SOD2 mRNA
CTD PMID:28659758, PMID:29477483 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SOD3 mRNA CTD PMID:28659758 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA CTD PMID:28659758 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA] CTD PMID:29751049 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
increases expression
EXP
ISO
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SRXN1 mRNA
Permethrin results in increased expression of SRXN1 mRNA
CTD PMID:28659758, PMID:30629241 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 increases expression EXP Permethrin results in increased expression of ST6GALNAC5 mRNA CTD PMID:19017407 NCBI chr 2:258,025,177...259,150,709
Ensembl chr 2:258,025,177...258,052,835
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Permethrin analog results in decreased expression of STAR mRNA; Permethrin results in decreased expression of STAR mRNA; Permethrin results in decreased expression of STAR protein CTD PMID:17463061, PMID:18455858, PMID:21745691 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Surf1 SURF1, cytochrome c oxidase assembly factor multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SURF1 mRNA CTD PMID:28659758 NCBI chr 3:5,461,717...5,464,560
Ensembl chr 3:4,869,795...4,872,632
JBrowse link
G Syp synaptophysin multiple interactions ISO [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of SYP protein CTD PMID:25785457 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity ISO Permethrin results in decreased activity of TDO2 protein CTD PMID:2547861 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
G Tent5c terminal nucleotidyltransferase 5C decreases expression ISO Permethrin results in decreased expression of TENT5C mRNA CTD PMID:30629241 NCBI chr 2:202,797,766...202,816,562
Ensembl chr 2:202,798,198...202,816,562
JBrowse link
G Tf transferrin decreases expression EXP Permethrin results in decreased expression of TF protein CTD PMID:26631339 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO Permethrin results in increased expression of TFF1 mRNA CTD PMID:12396874, PMID:20397420 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression
EXP Permethrin results in decreased expression of and results in decreased activity of TH protein
Permethrin results in decreased expression of TH mRNA
CTD PMID:15461254 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR4 protein]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PFKP mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of PPARA mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SLC2A4 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of SREBF1 mRNA]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein] CTD PMID:29751049 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr5 toll-like receptor 5 multiple interactions ISO [Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein]; TLR4 gene mutant form inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TLR5 protein] CTD PMID:29751049 NCBI chr13:101,364,784...101,385,764
Ensembl chr13:101,381,510...101,385,764
JBrowse link
G Tmed5 transmembrane p24 trafficking protein 5 increases expression ISO Permethrin results in increased expression of TMED5 mRNA CTD PMID:30629241 NCBI chr14:2,613,318...2,624,773
Ensembl chr14:2,613,406...2,633,950
JBrowse link
G Tnf tumor necrosis factor affects response to substance
multiple interactions
increases secretion
ISO
EXP
TNF protein affects the susceptibility to Permethrin
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of TNF protein
[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TNF mRNA; Butyric Acid inhibits the reaction [[Permethrin co-treated with Pyridostigmine Bromide co-treated with Corticosterone] results in increased expression of TNF mRNA]; Tetrodotoxin inhibits the reaction [Permethrin results in increased secretion of TNF protein]
CTD PMID:14617103, PMID:27655349, PMID:28659758, PMID:29751049 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein CTD PMID:12587291 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression ISO Permethrin results in decreased expression of TSC22D3 mRNA CTD PMID:30629241 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tspo translocator protein decreases expression ISO Permethrin analog results in decreased expression of TSPO mRNA; Permethrin results in decreased expression of TSPO mRNA CTD PMID:17463061, PMID:18455858, PMID:21745691 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Ttr transthyretin decreases expression EXP Permethrin results in decreased expression of TTR protein CTD PMID:26631339 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tubb4b tubulin, beta 4B class IVb increases expression ISO Permethrin results in increased expression of TUBB2C mRNA CTD PMID:30629241 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TXNRD1 mRNA CTD PMID:28659758 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TXNRD2 mRNA CTD PMID:28659758 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 increases expression EXP Permethrin results in increased expression of UAP1 mRNA CTD PMID:19017407 NCBI chr13:88,463,532...88,497,901
Ensembl chr13:88,463,532...88,497,901
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 decreases expression EXP Permethrin results in decreased expression of UBA52 protein CTD PMID:26631339 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UCP1 mRNA CTD PMID:28659758 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UCP2 mRNA CTD PMID:28659758 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression ISO Permethrin results in increased expression of UGDH mRNA CTD PMID:30629241 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Upp2 uridine phosphorylase 2 decreases expression ISO Permethrin results in decreased expression of UPP2 mRNA CTD PMID:30629241 NCBI chr 3:44,806,106...44,846,464
Ensembl chr 3:44,806,106...44,846,464
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UQCRB mRNA CTD PMID:28659758 NCBI chr 7:71,264,501...71,269,869
Ensembl chr 7:71,264,514...71,269,869
Ensembl chr 1:71,264,514...71,269,869
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions EXP [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of UQCRC1 mRNA CTD PMID:28659758 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Vnn1 vanin 1 increases expression ISO Permethrin results in increased expression of VNN1 mRNA CTD PMID:30629241 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Wnt10b Wnt family member 10B increases expression ISO Permethrin results in increased expression of WNT10B mRNA CTD PMID:12437293 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 increases expression EXP Permethrin results in increased expression of WRNIP1 mRNA CTD PMID:19017407 NCBI chr17:32,933,395...32,953,641
Ensembl chr17:32,933,396...32,953,641
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pesticide 16264
          acaricide 9039
            scabicide 459
              benzyl benzoate 8
              crotamiton 1
              ivermectin 110
              malaoxon 11
              malathion 96
              permethrin + 312
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.