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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:SCH 23390
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Accession:CHEBI:73297 term browser browse the term
Definition:A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, a methyl substituent at position 3, a chloro substituent at position 7 and a hydroxy substituent at position 8.
Synonyms:exact_synonym: 8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol
 related_synonym: 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol;   Formula=C17H18ClNO;   InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3;   InChIKey=GOTMKOSCLKVOGG-UHFFFAOYSA-N;   SMILES=CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1
 xref_mesh: MESH:C534628
 xref: PMID:21242715;   PMID:21864553;   PMID:23123352;   PMID:23320810;   PMID:23597562;   Reaxys:4323128;   Wikipedia:SCH_23390



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SCH 23390 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA CTD PMID:19564919 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA CTD PMID:19564919 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA CTD PMID:19564919 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abra actin-binding Rho activating protein multiple interactions EXP [Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA CTD PMID:19564919 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA CTD PMID:19564919 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA
SCH 23390 results in decreased expression of ADAMTS9 mRNA
CTD PMID:19564919 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions ISO SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Clozapine]; SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol] CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Ahsa2 activator of HSP90 ATPase homolog 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] CTD PMID:19564919 NCBI chr14:97,474,465...97,485,725
Ensembl chr14:97,476,817...97,485,657
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of AIF1 protein] CTD PMID:30922767 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Alg1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA CTD PMID:19564919 NCBI chr10:10,346,541...10,356,779
Ensembl chr10:10,346,536...10,356,750
JBrowse link
G Ankrd44 ankyrin repeat domain 44 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA
SCH 23390 results in decreased expression of ANKRD44 mRNA
CTD PMID:19564919 NCBI chr 9:56,126,746...56,427,661
Ensembl chr 9:56,126,747...56,427,508
JBrowse link
G Aplnr apelin receptor multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA CTD PMID:19564919 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Apold1 apolipoprotein L domain containing 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA CTD PMID:19564919 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions
decreases expression
EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]
SCH 23390 results in decreased expression of ARC mRNA
CTD PMID:11085305 PMID:19564919 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA
SCH 23390 results in increased expression of ARL5B mRNA
CTD PMID:19564919 NCBI chr17:77,955,749...77,983,745
Ensembl chr17:77,955,818...77,979,854
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA]
SCH 23390 results in decreased expression of ATF3 mRNA
CTD PMID:19564919 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein] CTD PMID:19564919 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Avp arginine vasopressin affects expression
multiple interactions
EXP SCH 23390 affects the expression of AVP mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA
CTD PMID:19564919 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA
SCH 23390 results in decreased expression of B3GALT4 mRNA
CTD PMID:19564919 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of BAX protein] CTD PMID:30922767 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of BCL2 protein]
CTD PMID:19879923 PMID:30922767 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l15 BCL2-like 15 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA CTD PMID:19564919 NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA CTD PMID:19564919 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 affects expression
multiple interactions
EXP SCH 23390 affects the expression of BHMT2 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA
CTD PMID:19564919 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
G C1qtnf7 C1q and TNF related 7 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of C1QTNF7 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA
CTD PMID:19564919 NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410
JBrowse link
G Ca4 carbonic anhydrase 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA CTD PMID:19564919 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] CTD PMID:20340177 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of CALCA protein] CTD PMID:11398184 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP SCH 23390 inhibits the reaction [SK&F 83959 promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Casp3 caspase 3 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased cleavage of CASP3 protein] CTD PMID:30922767 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cc2d1b coiled-coil and C2 domain containing 1B multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA CTD PMID:19564919 NCBI chr 5:123,353,289...123,367,343
Ensembl chr 5:123,353,292...123,367,318
JBrowse link
G Ccdc117 coiled-coil domain containing 117 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA CTD PMID:19564919 NCBI chr14:80,399,236...80,409,824
Ensembl chr14:80,400,294...80,409,659
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA CTD PMID:19564919 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA CTD PMID:19564919 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of CD86 mRNA] CTD PMID:30922767 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
EXP SCH 23390 results in increased expression of CDKN1A mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA
CTD PMID:19564919 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA CTD PMID:19564919 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cep104 centrosomal protein 104 multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA
SCH 23390 affects the expression of CEP104 mRNA
CTD PMID:19564919 NCBI chr 5:164,534,773...164,567,260
Ensembl chr 5:164,534,782...164,567,248
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA CTD PMID:19564919 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit decreases expression EXP SCH 23390 results in decreased expression of CHRNB1 mRNA CTD PMID:19564919 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA
SCH 23390 results in increased expression of CHRNE mRNA
CTD PMID:19564919 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of CHTF18 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA
CTD PMID:19564919 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA CTD PMID:19564919 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
JBrowse link
G Clvs2 clavesin 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA
SCH 23390 results in decreased expression of CLVS2 mRNA
CTD PMID:19564919 NCBI chr 1:23,735,272...23,762,997
Ensembl chr 1:23,735,272...23,842,692
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA
SCH 23390 results in increased expression of CNOT6L mRNA
CTD PMID:19564919 NCBI chr14:13,410,501...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP SCH 23390 results in decreased expression of COL3A1 mRNA CTD PMID:19564919 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Coq10b coenzyme Q10B multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA CTD PMID:19564919 NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP SCH 23390 inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[Dopamine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein] CTD PMID:14622123 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA CTD PMID:19564919 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
SCH 23390 results in increased expression of CRH mRNA
CTD PMID:11597771 PMID:19564919 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA CTD PMID:19564919 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
JBrowse link
G Cryab crystallin, alpha B multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA]
SCH 23390 results in increased expression of CRYAB mRNA
CTD PMID:19564919 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA CTD PMID:19564919 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog decreases expression EXP SCH 23390 results in decreased expression of CWC25 mRNA CTD PMID:19564919 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
JBrowse link
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYP2J10 mRNA CTD PMID:19564919 NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115
JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA CTD PMID:19564919 NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961
JBrowse link
G Dad1 defender against cell death 1 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA] CTD PMID:19564919 NCBI chr15:27,677,285...27,697,275
Ensembl chr15:27,677,268...27,697,347
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA] CTD PMID:19564919 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA CTD PMID:19564919 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx58 DEXD/H-box helicase 58 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of DDX58 mRNA CTD PMID:19564919 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Dmkn dermokine decreases expression EXP SCH 23390 results in decreased expression of DMKN mRNA CTD PMID:19564919 NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA CTD PMID:19564919 NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] CTD PMID:19564919 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] CTD PMID:19564919 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA CTD PMID:19564919 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA] CTD PMID:19564919 NCBI chr 5:57,176,840...57,185,492
Ensembl chr 5:57,176,845...57,185,490
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA] CTD PMID:19564919 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnase1 deoxyribonuclease 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA CTD PMID:19564919 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dok3 docking protein 3 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA
SCH 23390 results in increased expression of DOK3 mRNA
CTD PMID:19564919 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188
JBrowse link
G Drd1 dopamine receptor D1 affects binding
decreases activity
multiple interactions
ISO
EXP
SCH 23390 binds to DRD1 protein
SCH 23390 binds to Drd1 protein
SCH 23390 results in decreased activity of DRD1 protein
8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [SCH 23390 binds to DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to ethyl acetate]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to A 86929; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Amphetamine; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methylphenidate; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Nicotine; Aluminum inhibits the reaction [SCH 23390 binds to DRD1 protein]; boldine analog inhibits the reaction [SCH 23390 binds to DRD1 protein]; Cadmium inhibits the reaction [SCH 23390 binds to DRD1 protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; Copper inhibits the reaction [SCH 23390 binds to DRD1 protein]; Dopamine deficiency inhibits the reaction [SCH 23390 binds to DRD1 protein]; Gadolinium inhibits the reaction [SCH 23390 binds to DRD1 protein]; glyphosate inhibits the reaction [SCH 23390 binds to DRD1 protein]; Lanthanum inhibits the reaction [SCH 23390 binds to DRD1 protein]; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein]; Pilocarpine inhibits the reaction [SCH 23390 binds to DRD1 protein]; SCH 23390 binds to and results in decreased activity of DRD1 protein; SCH 23390 inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[Dopamine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [A 86929 binds to and results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [SK&F 82958 analog results in increased activity of DRD1 protein]]; SCH 23390 inhibits the reaction [SK&F 82958 analog results in increased activity of DRD1 protein]; Zinc Acetate inhibits the reaction [SCH 23390 binds to DRD1 protein]; zinc chloride inhibits the reaction [SCH 23390 binds to DRD1 protein]; Zinc Sulfate inhibits the reaction [SCH 23390 binds to DRD1 protein]
[SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to A 86929; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to adrogolide hydrochloride; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Amlodipine inhibits the reaction [SCH 23390 binds to DRD1 protein]; Diltiazem inhibits the reaction [SCH 23390 binds to DRD1 protein]; Flunarizine inhibits the reaction [SCH 23390 binds to DRD1 protein]; manidipine inhibits the reaction [SCH 23390 binds to DRD1 protein]; NR3C1 protein promotes the reaction [SCH 23390 binds to DRD1 protein]; SCH 23390 binds to and results in decreased activity of DRD1 protein; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; Verapamil inhibits the reaction [SCH 23390 binds to DRD1 protein]
SCH 23390 inhibits the reaction [A 68930 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [A 86929 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 86929 results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [dihydrexidine results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [dinapsoline affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [dinapsoline results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Dopamine affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [Dopamine results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Isoquinolines affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [Isoquinolines results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [SK&F 81297 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [SK&F 82958 affects the localization of DRD1 protein]
CTD
RGD
PMID:1418306 PMID:1724532 PMID:1833784 PMID:2213551 PMID:2891082 More... RGD:1600981 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole] CTD PMID:8103921 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP SCH 23390 inhibits the reaction [SK&F 83959 promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] CTD PMID:11701771 PMID:19564919 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA
SCH 23390 results in increased expression of DUSP14 mRNA
CTD PMID:19564919 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] CTD PMID:11701771 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Efnb1 ephrin B1 increases expression EXP SCH 23390 results in increased expression of EFNB1 mRNA CTD PMID:19564919 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157
JBrowse link
G Egfl7 EGF-like-domain, multiple 7 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA CTD PMID:19564919 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA CTD PMID:19564919 NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP SCH 23390 inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Methylphenidate results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:1347779 PMID:9890435 PMID:16549270 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 decreases expression EXP SCH 23390 results in decreased expression of EGR2 mRNA CTD PMID:19564919 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Egr4 early growth response 4 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA
SCH 23390 results in decreased expression of EGR4 mRNA
CTD PMID:19564919 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein] CTD PMID:17303341 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO SCH 23390 inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of ELK1 protein] CTD PMID:11553284 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA CTD PMID:19564919 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of ERRFI1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA
CTD PMID:19564919 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA CTD PMID:19564919 NCBI chr 5:129,479,774...129,499,018 JBrowse link
G Fadd Fas associated via death domain increases expression EXP SCH 23390 results in increased expression of FADD protein CTD PMID:18580876 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fam126b family with sequence similarity 126, member B multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FAM126B mRNA CTD PMID:19564919 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
JBrowse link
G Fcgr2a Fc gamma receptor IIa multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of FCGR3 mRNA] CTD PMID:30922767 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr2b Fc gamma receptor IIb multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of FCGR2B mRNA] CTD PMID:30922767 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fgf4 fibroblast growth factor 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA CTD PMID:19564919 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA
SCH 23390 results in increased expression of FMO2 mRNA
CTD PMID:19564919 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; [Pilocarpine co-treated with SCH 23390] results in increased expression of FOS protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [A 68930 results in increased expression of FOS mRNA]; SCH 23390 inhibits the reaction [Amphetamine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of FOS mRNA]; SCH 23390 inhibits the reaction [dihydrexidine results in increased expression of FOS mRNA]
SCH 23390 results in decreased expression of FOS mRNA
CTD PMID:2118661 PMID:8511714 PMID:8864302 PMID:9751140 PMID:11172061 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO
SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
SCH 23390 inhibits the reaction [Amphetamine results in increased expression of FOSB mRNA]
CTD PMID:16674926 PMID:18822274 PMID:19710318 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA
SCH 23390 results in increased expression of FTCD mRNA
CTD PMID:19564919 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA CTD PMID:19564919 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA CTD PMID:19564919 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA CTD PMID:19564919 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gas8 growth arrest specific 8 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA
SCH 23390 results in decreased expression of GAS8 mRNA
CTD PMID:19564919 NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA CTD PMID:19564919 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA
SCH 23390 results in decreased expression of GEM mRNA
CTD PMID:19564919 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein] CTD PMID:16088948 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfra4 GDNF family receptor alpha 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of GFRA4 mRNA CTD PMID:19564919 NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
JBrowse link
G Gja4 gap junction protein, alpha 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of GJA4 mRNA CTD PMID:19564919 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
JBrowse link
G Gpr150 G protein-coupled receptor 150 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of GPR150 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GPR150 mRNA
CTD PMID:19564919 NCBI chr 2:5,546,304...5,550,889
Ensembl chr 2:5,548,578...5,550,714
JBrowse link
G Gpr4 G protein-coupled receptor 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GPR4 mRNA CTD PMID:19564919 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
JBrowse link
G Gpr65 G-protein coupled receptor 65 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of GPR65 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GPR65 mRNA
CTD PMID:19564919 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
JBrowse link
G Gtsf2 gametocyte specific factor 2 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of GTSF2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GTSF2 mRNA
CTD PMID:19564919 NCBI chr 7:134,565,889...134,572,047
Ensembl chr 7:134,565,889...134,572,047
JBrowse link
G Hcrt hypocretin neuropeptide precursor multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of HCRT mRNA
SCH 23390 results in decreased expression of HCRT mRNA
CTD PMID:19564919 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of HERPUD1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HERPUD1 mRNA] CTD PMID:19564919 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes5 hes family bHLH transcription factor 5 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of HES5 mRNA CTD PMID:19564919 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Hist1h4b histone cluster 1 H4 family member B multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of HIST1H4B mRNA
SCH 23390 results in increased expression of HIST1H4B mRNA
CTD PMID:19564919 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
JBrowse link
G Hmga1 high mobility group AT-hook 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA CTD PMID:19564919 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of HMOX1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein] CTD PMID:19564919 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP SCH 23390 inhibits the reaction [Methylphenidate results in increased expression of HOMER1 mRNA] CTD PMID:16549270 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hrc histidine rich calcium binding protein decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of HRC mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HRC mRNA
CTD PMID:19564919 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of HSF2BP mRNA
SCH 23390 results in decreased expression of HSF2BP mRNA
CTD PMID:19564919 NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
JBrowse link
G Hspa12b heat shock protein family A (Hsp70) member 12B multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of HSPA12B mRNA] CTD PMID:19564919 NCBI chr 3:118,346,322...118,364,737
Ensembl chr 3:118,346,354...118,364,737
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of HSPA5 mRNA; SCH 23390 inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA] CTD PMID:17303341 PMID:19564919 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of HSPB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB1 mRNA] CTD PMID:19564919 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB8 mRNA] CTD PMID:19564919 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Icam2 intercellular adhesion molecule 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ICAM2 mRNA CTD PMID:19564919 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
JBrowse link
G Idnk Idnk, gluconokinase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of IDNK mRNA CTD PMID:19564919 NCBI chr17:6,483,575...6,490,780
Ensembl chr17:6,483,576...6,490,905
JBrowse link
G Il10 interleukin 10 multiple interactions ISO SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 mRNA]; SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 protein] CTD PMID:16985181 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA
SCH 23390 results in increased expression of IL1A mRNA
CTD PMID:19564919 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Impg1 interphotoreceptor matrix proteoglycan 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of IMPG1 mRNA
SCH 23390 results in decreased expression of IMPG1 mRNA
CTD PMID:19564919 NCBI chr 8:81,243,624...81,389,722
Ensembl chr 8:81,243,624...81,389,722
JBrowse link
G Iqcf1 IQ motif containing F1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of IQCF1 mRNA
SCH 23390 results in increased expression of IQCF1 mRNA
CTD PMID:19564919 NCBI chr 8:107,129,462...107,133,242
Ensembl chr 8:107,130,704...107,133,249
JBrowse link
G Jaml junction adhesion molecule like multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of JAML mRNA
SCH 23390 results in increased expression of JAML mRNA
CTD PMID:19564919 NCBI chr 8:45,384,836...45,415,459
Ensembl chr 8:45,383,495...45,416,565
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of JUNB mRNA; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]] CTD PMID:1347779 PMID:19564919 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kif15 kinesin family member 15 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of KIF15 mRNA
SCH 23390 results in decreased expression of KIF15 mRNA
CTD PMID:19564919 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Klf5 Kruppel-like factor 5 decreases expression EXP SCH 23390 results in decreased expression of KLF5 mRNA CTD PMID:19564919 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klhl15 kelch-like family member 15 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of KLHL15 mRNA
SCH 23390 results in increased expression of KLHL15 mRNA
CTD PMID:19564919 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069
JBrowse link
G Krt7 keratin 7 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of KRT7 mRNA
SCH 23390 results in decreased expression of KRT7 mRNA
CTD PMID:19564919 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of L3MBTL1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of L3MBTL1 mRNA
CTD PMID:19564919 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lgals9 galectin 9 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of LGALS9 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LGALS9 mRNA
CTD PMID:19564919 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Lrrc28 leucine rich repeat containing 28 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LRRC28 mRNA CTD PMID:19564919 NCBI chr 1:121,116,833...121,245,805
Ensembl chr 1:121,127,733...121,245,784
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTBP1 mRNA
SCH 23390 results in decreased expression of LTBP1 mRNA
CTD PMID:19564919 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Ltc4s leukotriene C4 synthase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTC4S mRNA CTD PMID:19564919 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Ltk leukocyte receptor tyrosine kinase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTK mRNA CTD PMID:19564919 NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369
JBrowse link
G Lurap1 leucine rich adaptor protein 1 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of LURAP1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LURAP1 mRNA
CTD PMID:19564919 NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:129,614,137...129,628,766
JBrowse link
G Lyrm9 LYR motif containing 9 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of LYRM9 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LYRM9 mRNA
CTD PMID:19564919 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of MAFF mRNA CTD PMID:19564919 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of MANF mRNA] CTD PMID:19564919 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]
SCH 23390 inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of MAPK1 protein]; SCH 23390 inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]
CTD PMID:11553284 PMID:19187092 PMID:20956312 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
SCH 23390 inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of MAPK3 protein]; SCH 23390 inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]
CTD PMID:11553284 PMID:19187092 PMID:20956312 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of MASTL mRNA
SCH 23390 affects the expression of MASTL mRNA
CTD PMID:19564919 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Mc4r melanocortin 4 receptor multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of MC4R mRNA CTD PMID:19564919 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MCM8 mRNA
SCH 23390 results in decreased expression of MCM8 mRNA
CTD PMID:19564919 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008
JBrowse link
G Mfsd10 major facilitator superfamily domain containing 10 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MFSD10 mRNA CTD PMID:19564919 NCBI chr14:76,103,762...76,107,385
Ensembl chr14:76,103,815...76,107,377
JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MN1 mRNA CTD PMID:19564919 NCBI chr12:45,184,060...45,220,102
Ensembl chr12:45,183,085...45,221,651
JBrowse link
G Mpg N-methylpurine-DNA glycosylase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MPG mRNA CTD PMID:19564919 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MUS81 mRNA CTD PMID:19564919 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843
JBrowse link
G Mylk myosin light chain kinase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of MYLK mRNA
SCH 23390 results in decreased expression of MYLK mRNA
CTD PMID:19564919 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nab2 Ngfi-A binding protein 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NAB2 mRNA
SCH 23390 results in increased expression of NAB2 mRNA
CTD PMID:19564919 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NDST3 mRNA
SCH 23390 results in decreased expression of NDST3 mRNA
CTD PMID:19564919 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NEURL2 mRNA
SCH 23390 results in decreased expression of NEURL2 mRNA
CTD PMID:19564919 NCBI chr 3:153,566,659...153,569,380
Ensembl chr 3:153,566,660...153,569,380
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 affects expression
multiple interactions
EXP SCH 23390 affects the expression of NFATC3 mRNA
SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC3 protein]
CTD PMID:15644446 PMID:19564919 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NFATC4 mRNA; SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC4 protein] CTD PMID:15644446 PMID:19564919 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFE2L2 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of NFE2L2 mRNA] CTD PMID:19564919 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NFIL3 mRNA CTD PMID:19564919 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP SCH 23390 inhibits the reaction [Cocaine results in increased activity of NFKBIA protein] CTD PMID:19183502 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nkx2-6 NK2 homeobox 6 affects expression
multiple interactions
EXP SCH 23390 affects the expression of NKX2-6 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of NKX2-6 mRNA
CTD PMID:19564919 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247
JBrowse link
G Nkx6-2 NK6 homeobox 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NKX6-2 mRNA CTD PMID:19564919 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NOTUM mRNA CTD PMID:19564919 NCBI chr10:105,933,245...105,940,315
Ensembl chr10:105,933,249...105,940,315
JBrowse link
G Npas4 neuronal PAS domain protein 4 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NPAS4 mRNA CTD PMID:19564919 NCBI chr 1:202,281,260...202,298,681
Ensembl chr 1:202,281,958...202,286,724
JBrowse link
G Nptx2 neuronal pentraxin 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NPTX2 mRNA CTD PMID:19564919 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345
JBrowse link
G Npy neuropeptide Y increases expression
multiple interactions
EXP SCH 23390 results in increased expression of NPY protein
[Prazosin co-treated with SCH 23390] inhibits the reaction [Phenylpropanolamine results in decreased expression of NPY protein]
CTD PMID:7644023 PMID:21989786 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO NR3C1 protein promotes the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:11226678 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A2 mRNA
SCH 23390 results in increased expression of NR4A2 mRNA
CTD PMID:19564919 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A3 mRNA CTD PMID:19564919 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nrm nurim multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NRM mRNA CTD PMID:19564919 NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802
JBrowse link
G Nup210l nucleoporin 210-like multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NUP210L mRNA
SCH 23390 results in increased expression of NUP210L mRNA
CTD PMID:19564919 NCBI chr 2:175,545,999...175,665,332
Ensembl chr 2:175,547,988...175,665,332
JBrowse link
G Obsl1 obscurin like cytoskeletal adaptor 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of OBSL1 mRNA CTD PMID:19564919 NCBI chr 9:76,967,802...76,993,565
Ensembl chr 9:76,974,253...76,993,560
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of OGG1 mRNA CTD PMID:19564919 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Olr1708 olfactory receptor 1708 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of OLR1708 mRNA
SCH 23390 results in increased expression of OLR1708 mRNA
CTD PMID:19564919 NCBI chr20:872,996...873,910
Ensembl chr20:833,838...846,753
JBrowse link
G Olr1724 olfactory receptor 1724 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of OLR1724 mRNA
SCH 23390 results in increased expression of OLR1724 mRNA
CTD PMID:19564919 NCBI chr20:1,097,181...1,098,110
Ensembl chr20:1,097,181...1,098,110
JBrowse link
G Oxgr1 oxoglutarate receptor 1 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of OXGR1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of OXGR1 mRNA
CTD PMID:19564919 NCBI chr15:97,145,947...97,146,960
Ensembl chr15:97,144,293...97,166,612
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of OXT mRNA
SCH 23390 affects the expression of OXT mRNA
CTD PMID:19564919 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA1 mRNA CTD PMID:19564919 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA2 mRNA
SCH 23390 results in increased expression of P4HA2 mRNA
CTD PMID:19564919 NCBI chr10:38,243,047...38,271,989
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G Padi6 peptidyl arginine deiminase 6 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of PADI6 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PADI6 mRNA
CTD PMID:19564919 NCBI chr 5:153,022,089...153,037,376
Ensembl chr 5:153,021,965...153,037,414
JBrowse link
G Pard6g par-6 family cell polarity regulator gamma multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of PARD6G mRNA
SCH 23390 affects the expression of PARD6G mRNA
CTD PMID:19564919 NCBI chr18:73,498,119...73,565,048
Ensembl chr18:73,498,021...73,565,029
JBrowse link
G Pclaf PCNA clamp associated factor multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PCLAF mRNA CTD PMID:19564919 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PCSK1 mRNA
SCH 23390 affects the expression of PCSK1 mRNA
CTD PMID:19564919 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
JBrowse link
G Pde8a phosphodiesterase 8A multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PDE8A mRNA CTD PMID:19564919 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA] CTD PMID:19564919 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PDK4 mRNA
SCH 23390 results in increased expression of PDK4 mRNA
CTD PMID:19564919 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PEMT mRNA
SCH 23390 results in decreased expression of PEMT mRNA
CTD PMID:19564919 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Pgap6 post-glycosylphosphatidylinositol attachment to proteins 6 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PGAP6 mRNA CTD PMID:19564919 NCBI chr10:15,138,918...15,151,581
Ensembl chr10:15,138,959...15,148,431
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PIK3R5 mRNA CTD PMID:19564919 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of PIK3R6 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PIK3R6 mRNA
CTD PMID:19564919 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243
JBrowse link
G Pitx3 paired-like homeodomain 3 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of PITX3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PITX3 mRNA
CTD PMID:19564919 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892
JBrowse link
G Pkp2 plakophilin 2 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of PKP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PKP2 mRNA
CTD PMID:19564919 NCBI chr11:84,661,783...84,727,730 JBrowse link
G Pla1a phospholipase A1 member A multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PLA1A mRNA CTD PMID:19564919 NCBI chr11:62,320,117...62,357,779
Ensembl chr11:62,320,493...62,357,779
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PLAGL1 mRNA CTD PMID:19564919 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of PLAT mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]
CTD PMID:15659235 PMID:19564919 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PLEKHF1 mRNA CTD PMID:19564919 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Pmch pro-melanin-concentrating hormone multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of PMCH mRNA
SCH 23390 affects the expression of PMCH mRNA
CTD PMID:19564919 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PPIP5K2 mRNA CTD PMID:19564919 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP1R15A mRNA] CTD PMID:19564919 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CA protein] CTD PMID:15644446 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CB protein] CTD PMID:15644446 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3R2 protein] CTD PMID:15644446 NCBI chr 5:64,026,903...64,027,898
Ensembl chr 5:64,026,903...64,032,548
JBrowse link
G Prg4 proteoglycan 4 affects expression
multiple interactions
EXP SCH 23390 affects the expression of PRG4 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of PRG4 mRNA
CTD PMID:19564919 NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119
JBrowse link
G Prkx protein kinase, X-linked increases expression EXP SCH 23390 results in increased expression of PRKX mRNA CTD PMID:19564919 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669
JBrowse link
G Prok2 prokineticin 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PROK2 mRNA
SCH 23390 results in increased expression of PROK2 mRNA
CTD PMID:19564919 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Prom1 prominin 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PROM1 mRNA CTD PMID:19564919 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PTH1R mRNA CTD PMID:19564919 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PYCARD mRNA
SCH 23390 results in decreased expression of PYCARD mRNA
CTD PMID:19564919 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rab3d RAB3D, member RAS oncogene family multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RAB3D mRNA CTD PMID:19564919 NCBI chr 8:20,438,622...20,449,269
Ensembl chr 8:20,439,294...20,449,185
JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression EXP SCH 23390 results in increased expression of RASD1 mRNA CTD PMID:19564919 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rasl11a RAS-like family 11 member A multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RASL11A mRNA CTD PMID:19564919 NCBI chr12:8,258,148...8,262,576
Ensembl chr12:8,258,159...8,262,576
JBrowse link
G Rassf9 Ras association domain family member 9 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RASSF9 mRNA CTD PMID:19564919 NCBI chr 7:37,599,720...37,631,553
Ensembl chr 7:37,599,720...37,635,245
JBrowse link
G Rbm3 RNA binding motif protein 3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM3 mRNA CTD PMID:19564919 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580
JBrowse link
G Rbm43 RNA binding motif protein 43 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of RBM43 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM43 mRNA
CTD PMID:19564919 NCBI chr 3:36,394,431...36,404,757
Ensembl chr 3:36,395,346...36,404,816
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP SCH 23390 inhibits the reaction [Cocaine results in increased activity of RELA protein] CTD PMID:19183502 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1305347 similar to RIKEN cDNA 2610528J11 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1305347 mRNA CTD PMID:19564919 NCBI chr 5:132,048,687...132,051,925
Ensembl chr 5:132,048,773...132,051,925
JBrowse link
G RGD1308117 similar to 9930012K11Rik protein multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1308117 mRNA
SCH 23390 results in decreased expression of RGD1308117 mRNA
CTD PMID:19564919 NCBI chr15:45,228,615...45,235,274
Ensembl chr15:45,228,615...45,233,254
JBrowse link
G RGD1565166 similar to MGC45438 protein multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1565166 mRNA
SCH 23390 results in decreased expression of RGD1565166 mRNA
CTD PMID:19564919 NCBI chr10:10,361,909...10,371,046
Ensembl chr10:10,361,948...10,371,046
JBrowse link
G Rgs1 regulator of G-protein signaling 1 multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of RGS1 mRNA
SCH 23390 affects the expression of RGS1 mRNA
CTD PMID:19564919 NCBI chr13:56,018,529...56,022,939
Ensembl chr13:56,018,554...56,022,984
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions EXP SCH 23390 inhibits the reaction [Amphetamine results in increased expression of RGS2 mRNA] CTD PMID:10098858 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 affects expression
increases expression
multiple interactions
EXP SCH 23390 affects the expression of RGS4 protein
SCH 23390 results in increased expression of RGS4 mRNA
Dextroamphetamine promotes the reaction [SCH 23390 results in increased expression of RGS4 mRNA]
CTD PMID:16539683 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RHBDF1 mRNA
SCH 23390 results in decreased expression of RHBDF1 mRNA
CTD PMID:19564919 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763
JBrowse link
G Rhod ras homolog family member D multiple interactions EXP [Methamphetamine co-treated with SCH 23390] affects the expression of RHOD mRNA CTD PMID:19564919 NCBI chr 1:201,708,699...201,724,405
Ensembl chr 1:201,708,699...201,722,632
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of RIMS2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of RIMS2 mRNA
CTD PMID:19564919 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491
JBrowse link
G Ripply2 ripply transcriptional repressor 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RIPPLY2 mRNA CTD PMID:19564919 NCBI chr 8:87,974,444...87,978,996
Ensembl chr 8:87,974,776...87,978,969
JBrowse link
G Rnf225 ring finger protein 225 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of RNF225 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of RNF225 mRNA
CTD PMID:19564919 NCBI chr 1:73,543,598...73,546,269
Ensembl chr 1:73,543,598...73,546,269
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 multiple interactions ISO SCH 23390 inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of RPS6KA5 protein] CTD PMID:19187092 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
JBrowse link
G Rpusd3 RNA pseudouridine synthase D3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RPUSD3 mRNA CTD PMID:19564919 NCBI chr 4:146,553,230...146,562,794
Ensembl chr 4:146,558,562...146,562,794
JBrowse link
G Rtp1 receptor (chemosensory) transporter protein 1 multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RTP1 mRNA
SCH 23390 affects the expression of RTP1 mRNA
CTD PMID:19564919 NCBI chr11:77,422,982...77,425,498
Ensembl chr11:77,422,982...77,425,498
JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO SCH 23390 inhibits the reaction [SK&F 82958 results in increased expression of RYR1 protein] CTD PMID:22504960 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions ISO SCH 23390 inhibits the reaction [SK&F 82958 results in increased expression of RYR2 protein] CTD PMID:22504960 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of S100A11 mRNA
SCH 23390 results in decreased expression of S100A11 mRNA
CTD PMID:19564919 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G Serpinb9 serpin family B member 9 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SERPINB9 mRNA CTD PMID:19564919 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Sertad1 SERTA domain containing 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SERTAD1 mRNA CTD PMID:19564919 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of SFRP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SFRP2 mRNA
CTD PMID:19564919 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of SGK1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SGK1 mRNA
CTD PMID:19564919 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sigirr single Ig and TIR domain containing multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SIGIRR mRNA CTD PMID:19564919 NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]] CTD PMID:20956312 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
G Sik1 salt-inducible kinase 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SIK1 mRNA CTD PMID:19564919 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Six4 SIX homeobox 4 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of SIX4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SIX4 mRNA
CTD PMID:19564919 NCBI chr 6:91,802,328...91,816,062
Ensembl chr 6:91,802,329...91,815,992
JBrowse link
G Slc16a11 solute carrier family 16, member 11 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A11 mRNA
SCH 23390 results in decreased expression of SLC16A11 mRNA
CTD PMID:19564919 NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915
JBrowse link
G Slc16a13 solute carrier family 16, member 13 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A13 mRNA CTD PMID:19564919 NCBI chr10:54,925,973...54,937,860
Ensembl chr10:54,926,760...54,937,788
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC18A2 protein] CTD PMID:30922767 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc22a13l1 solute carrier family 22 member 13-like 1 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of SLC22A13 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC22A13 mRNA
CTD PMID:19564919 NCBI chr 8:118,958,209...118,972,614
Ensembl chr 8:118,961,000...118,966,046
JBrowse link
G Slc35b2 solute carrier family 35 member B2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC35B2 mRNA CTD PMID:19564919 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
JBrowse link
G Slc38a5 solute carrier family 38, member 5 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC38A5 mRNA CTD PMID:19564919 NCBI chr  X:14,213,727...14,222,498
Ensembl chr  X:14,213,729...14,222,498
JBrowse link
G Slc39a12 solute carrier family 39 member 12 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SLC39A12 mRNA CTD PMID:19564919 NCBI chr17:77,353,761...77,440,381
Ensembl chr17:77,353,805...77,440,353
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC40A1 mRNA CTD PMID:19564919 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SLC5A3 mRNA CTD PMID:19564919 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc66a1 solute carrier family 66 member 1 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of SLC66A1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC66A1 mRNA
CTD PMID:19564919 NCBI chr 5:151,537,870...151,552,338
Ensembl chr 5:151,542,376...151,552,259
JBrowse link
G Slc6a13 solute carrier family 6 member 13 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of SLC6A13 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC6A13 mRNA
CTD PMID:19564919 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC6A3 protein] CTD PMID:30922767 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Smad3 SMAD family member 3 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of SMAD3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SMAD3 mRNA
CTD PMID:19564919 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Snx27 sorting nexin 27 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of SNX27 mRNA alternative form] CTD PMID:12740601 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906
JBrowse link
G Sox17 SRY-box transcription factor 17 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX17 mRNA CTD PMID:19564919 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Sox18 SRY-box transcription factor 18 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX18 mRNA CTD PMID:19564919 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
JBrowse link
G Spaca9 sperm acrosome associated 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPACA9 mRNA
SCH 23390 results in decreased expression of SPACA9 mRNA
CTD PMID:19564919 NCBI chr 3:12,019,376...12,028,801
Ensembl chr 3:12,019,363...12,029,119
JBrowse link
G Spag8 sperm associated antigen 8 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPAG8 mRNA CTD PMID:19564919 NCBI chr 5:57,901,681...57,903,894
Ensembl chr 5:57,901,682...57,903,894
JBrowse link
G Spata6l spermatogenesis associated 6-like multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPATA6L mRNA CTD PMID:19564919 NCBI chr 1:226,630,470...226,682,979
Ensembl chr 1:226,641,518...226,682,884
JBrowse link
G St13 ST13, Hsp70 interacting protein multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ST13 mRNA] CTD PMID:19564919 NCBI chr 7:112,891,007...112,925,727 JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ST8SIA6 mRNA CTD PMID:19564919 NCBI chr17:76,740,755...76,883,766
Ensembl chr17:76,745,224...76,884,299
JBrowse link
G Steap1 STEAP family member 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of STEAP1 mRNA
SCH 23390 results in increased expression of STEAP1 mRNA
CTD PMID:19564919 NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 affects expression EXP SCH 23390 affects the expression of STRA6 mRNA CTD PMID:19564919 NCBI chr 8:58,549,743...58,568,861
Ensembl chr 8:58,549,736...58,568,860
JBrowse link
G Sv2c synaptic vesicle glycoprotein 2c increases expression
multiple interactions
EXP SCH 23390 results in increased expression of SV2C mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SV2C mRNA
CTD PMID:19564919 NCBI chr 2:27,232,933...27,428,479
Ensembl chr 2:27,232,933...27,428,477
JBrowse link
G Swt1 SWT1 RNA endoribonuclease homolog multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SWT1 mRNA CTD PMID:19564919 NCBI chr13:63,452,494...63,509,982
Ensembl chr13:63,452,496...63,509,980
JBrowse link
G Syt2 synaptotagmin 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of SYT2 mRNA
SCH 23390 results in increased expression of SYT2 mRNA
CTD PMID:19564919 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
JBrowse link
G Tas1r1 taste 1 receptor member 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TAS1R1 mRNA
SCH 23390 results in decreased expression of TAS1R1 mRNA
CTD PMID:19564919 NCBI chr 5:162,533,838...162,546,408
Ensembl chr 5:162,533,841...162,545,562
JBrowse link
G Tecta tectorin alpha multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TECTA mRNA CTD PMID:19564919 NCBI chr 8:42,707,962...42,779,726
Ensembl chr 8:42,707,962...42,779,707
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of TENT5A mRNA CTD PMID:19564919 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TERF1 mRNA CTD PMID:19564919 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein]; SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:16088948 PMID:30922767 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TIE1 mRNA CTD PMID:19564919 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TLR2 mRNA CTD PMID:19564919 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tmem123 transmembrane protein 123 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM123 mRNA CTD PMID:19564919 NCBI chr 8:4,922,098...4,952,228
Ensembl chr 8:4,922,098...4,952,224
JBrowse link
G Tmem125 transmembrane protein 125 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM125 mRNA CTD PMID:19564919 NCBI chr 5:132,063,162...132,064,566
Ensembl chr 5:132,059,554...132,079,297
Ensembl chr 5:132,059,554...132,079,297
JBrowse link
G Tmem18 transmembrane protein 18 decreases expression
multiple interactions
EXP SCH 23390 results in decreased expression of TMEM18 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM18 mRNA
CTD PMID:19564919 NCBI chr 6:47,206,845...47,214,294
Ensembl chr 6:47,206,845...47,214,294
JBrowse link
G Tmem252 transmembrane protein 252 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of TMEM252 mRNA
SCH 23390 results in increased expression of TMEM252 mRNA
CTD PMID:19564919 NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943
JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMTC3 mRNA
SCH 23390 results in increased expression of TMTC3 mRNA
CTD PMID:19564919 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of TSC22D3 mRNA CTD PMID:19564919 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ttk Ttk protein kinase multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TTK mRNA CTD PMID:19564919 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Ttll9 tubulin tyrosine ligase like 9 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TTLL9 mRNA CTD PMID:19564919 NCBI chr 3:141,429,351...141,475,965
Ensembl chr 3:141,429,444...141,475,865
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of UBA2 mRNA
SCH 23390 results in increased expression of UBA2 mRNA
CTD PMID:19564919 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of UPP1 mRNA CTD PMID:19564919 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 increases expression
multiple interactions
EXP SCH 23390 results in increased expression of USPL1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of USPL1 mRNA
CTD PMID:19564919 NCBI chr12:5,823,460...5,850,470
Ensembl chr12:5,823,359...5,850,366
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of VEGFA mRNA] CTD PMID:19564919 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased splicing of XBP1 mRNA] CTD PMID:19564919 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Ybx1 Y box binding protein 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of YBX1 mRNA
SCH 23390 results in increased expression of YBX1 mRNA
CTD PMID:19564919 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Zfp189 zinc finger protein 189 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP189 mRNA CTD PMID:19564919 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
JBrowse link
G Zfp287 zinc finger protein 287 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP287 mRNA
SCH 23390 results in decreased expression of ZFP287 mRNA
CTD PMID:19564919 NCBI chr10:47,395,650...47,415,610
Ensembl chr10:47,397,285...47,439,755
JBrowse link
G Zfp324 zinc finger protein 324 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP324 mRNA CTD PMID:19564919 NCBI chr 1:73,591,411...73,600,601
Ensembl chr 1:73,591,491...73,597,894
JBrowse link
G Zfp36 zinc finger protein 36 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP36 mRNA CTD PMID:19564919 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp688 zinc finger protein 688 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP688 mRNA CTD PMID:19564919 Ensembl chr 1:182,039,931...182,043,103 JBrowse link
G Zic2 Zic family member 2 multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZIC2 mRNA CTD PMID:19564919 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        pharmacological role 18837
          neurotransmitter agent 16451
            dopaminergic agent 5110
              dopaminergic antagonist 1196
                SCH 23390 295
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    main group molecular entity 19698
                      s-block molecular entity 19479
                        hydrogen molecular entity 19471
                          hydrides 18834
                            inorganic hydride 17691
                              pnictogen hydride 17671
                                nitrogen hydride 17543
                                  azane 17278
                                    ammonia 17277
                                      organic amino compound 17277
                                        tertiary amino compound 8697
                                          SCH 23390 295
paths to the root