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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cholecystokinin antagonist
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Accession:CHEBI:73296 term browser browse the term
Definition:A hormone antagonist that inhibits the action of the peptide hormone cholecystokinin.
Synonyms:related_synonym: CCK antagonist;   CCK antagonists;   cholecystokinin antagonists
 xref: Wikipedia:Cholecystokinin_antagonist


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devazepide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cck cholecystokinin multiple interactions ISO Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]] CTD PMID:32916201 NCBI chr 8:121,153,499...121,160,194 JBrowse link
G Cckar cholecystokinin A receptor multiple interactions ISO Devazepide inhibits the reaction [CCKAR protein results in increased susceptibility to denatonium] CTD PMID:18003792 NCBI chr14:57,292,397...57,300,747 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Devazepide inhibits the reaction [8-sulfocholecystokinin octapeptide results in increased expression of FOS protein] CTD PMID:9372230 NCBI chr 6:105,121,170...105,124,036 JBrowse link
G Il6 interleukin 6 multiple interactions ISO Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]] CTD PMID:32916201 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]] CTD PMID:32916201 NCBI chr20:3,622,011...3,624,629 JBrowse link
gastrin-17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC2 CTD PMID:17704804 NCBI chr 8:4,968,856...4,989,325 JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC3 CTD PMID:17704804 NCBI chr 8:5,000,844...5,028,470 JBrowse link
G Cckbr cholecystokinin B receptor multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC2; [gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC3; [gastrin 17 co-treated with CCKBR protein] results in increased expression of IER3 mRNA CTD PMID:17704804 NCBI chr 1:159,771,733...159,781,738 JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [gastrin 17 co-treated with CCKBR protein] results in increased expression of IER3 mRNA CTD PMID:17704804 NCBI chr20:2,928,378...2,929,582 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases activity ISO gastrin 17 results in decreased activity of NFKB1 protein CTD PMID:15623601 NCBI chr 2:224,016,214...224,132,135 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases activity ISO gastrin 17 results in decreased activity of RELA protein CTD PMID:15623601 NCBI chr 1:202,925,001...202,935,484 JBrowse link
G Sele selectin E decreases expression ISO gastrin 17 results in decreased expression of SELE protein CTD PMID:15623601 NCBI chr13:76,402,841...76,412,741 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    role 19708
      biological role 19708
        pharmacological role 18815
          antagonist 16263
            hormone antagonist 11569
              cholecystokinin antagonist 12
                asperlicin C 0
                asperlicin E 0
                devazepide 5
                gastrin + 7
                lorglumide 0
                lorglumide sodium 0
                proglumide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    role 19708
      application 19396
        pharmaceutical 19294
          drug 19294
            receptor modulator 18848
              hormone receptor modulator 18837
                hormone antagonist 11569
                  cholecystokinin antagonist 12
                    asperlicin C 0
                    asperlicin E 0
                    devazepide 5
                    gastrin + 7
                    lorglumide 0
                    lorglumide sodium 0
                    proglumide + 0
paths to the root