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Accession:CHEBI:73275 term browser browse the term
Definition:An organochlorine compound that is a selective estrogen receptor modulator; used for treatment of dyspareunia.
Synonyms:exact_synonym: 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethanol
 related_synonym: 2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol;   2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol;   Deamino-hydroxytoremifene;   FC-1271a;   Fc-1271;   Formula=C24H23ClO2;   InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-;   InChIKey=LUMKNAVTFCDUIE-VHXPQNKSSA-N;   Osphena;   SMILES=OCCOc1ccc(cc1)C(\\c1ccccc1)=C(\\CCCl)c1ccccc1
 xref: CAS:128607-22-7;   Drug_Central:4749;   KEGG:D08958
 xref_mesh: MESH:C119141
 xref: PMID:10845810;   PMID:11457665;   PMID:19182697;   PMID:19466874;   PMID:19533603;   PMID:19857095;   PMID:20032798;   PMID:20073065;   PMID:20107426;   PMID:20429673;   PMID:20485909;   PMID:21564348;   PMID:21654612;   PMID:21926925;   PMID:22011753;   PMID:22196312;   PMID:23062036;   PMID:23096251;   PMID:23332519;   PMID:23361170;   Patent:CN101636372;   Patent:EP2275098;   Patent:EP2286806;   Patent:US2005182143;   Patent:US2005187301;   Patent:US2005187302;   Patent:US2008207956;   Patent:US2011015448;   Patent:WO2005105052;   Patent:WO2010107475;   Reaxys:10283864;   Wikipedia:Ospemifene

show annotations for term's descendants       view all columns           Sort by:
ospemifene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      application 19363
        anti-inflammatory agent 14954
          ospemifene 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19398
                        hydrogen molecular entity 19388
                          hydrides 18363
                            organic hydride 17714
                              organic fundamental parent 17714
                                hydrocarbon 17201
                                  olefin 7175
                                    acyclic olefin 7155
                                      stilbene 3353
                                        ospemifene 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.