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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxidative phosphorylation inhibitor
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Accession:CHEBI:73267 term browser browse the term
Definition:Any compound that inhibits oxidative phosphorylation.
Synonyms:related_synonym: oxidative phosphorylation inhibitors


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2,4-dinitrophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO 2,4-Dinitrophenol results in increased expression of APAF1 mRNA alternative form CTD PMID:17064354 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G App amyloid beta precursor protein affects localization
multiple interactions
ISO 2,4-Dinitrophenol affects the localization of APP protein
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]
CTD PMID:18949129 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of CIDEA mRNA CTD PMID:24872412 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO 2,4-Dinitrophenol results in increased expression of COX4I1 mRNA CTD PMID:11784294 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
ISO
EXP
2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
2,4-Dinitrophenol results in increased activity of CYP1A1 protein
CTD PMID:18493746 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of DIO2 mRNA CTD PMID:24872412 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of FGF21 mRNA CTD PMID:24872412 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor multiple interactions ISO 2,4-Dinitrophenol inhibits the reaction [GNRHR protein results in increased transport of deslorelin] CTD PMID:15212170 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Gpx4 glutathione peroxidase 4 decreases response to substance EXP GPX4 protein results in decreased susceptibility to 2,4-Dinitrophenol CTD PMID:19818760 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO 2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium]; Glyburide inhibits the reaction [2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium]] CTD PMID:15949470 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Lep leptin multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of LEP mRNA CTD PMID:24872412 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO 2,4-Dinitrophenol results in increased expression of NRF1 mRNA CTD PMID:11784294 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Prdm16 PR/SET domain 16 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of PRDM16 mRNA CTD PMID:24872412 NCBI chr 5:171,662,277...171,711,561
Ensembl chr 5:171,662,277...171,710,316
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of SCD1 mRNA CTD PMID:24872412 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO 2,4-Dinitrophenol inhibits the reaction [SLC16A1 protein results in increased uptake of Lactic Acid] CTD PMID:15804185 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO 2,4-Dinitrophenol inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Smn1 survival of motor neuron 1, telomeric increases expression ISO 2,4-Dinitrophenol results in increased expression of SMN1 mRNA alternative form CTD PMID:17064354 NCBI chr 2:30,360,101...30,371,147
Ensembl chr 2:30,360,100...30,371,147
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2,4-Dinitrophenol results in increased expression of SRXN1 protein CTD PMID:27358234 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of UCP1 mRNA CTD PMID:24872412 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        inhibitor 18241
          oxidative phosphorylation inhibitor 20
            2,4-dinitrophenol + 20
            N-tert-butyl-N'-(2,6-diisopropyl-4-phenoxyphenyl)methanediimine 0
            diafenthiuron + 0
            diafenthiuron-S-oxide 0
paths to the root