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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxidative phosphorylation inhibitor
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Accession:CHEBI:73267 term browser browse the term
Definition:Any compound that inhibits oxidative phosphorylation.
Synonyms:related_synonym: oxidative phosphorylation inhibitors



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2,4-dinitrophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO 2,4-Dinitrophenol results in increased expression of APAF1 mRNA alternative form CTD PMID:17064354 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G App amyloid beta precursor protein affects localization
multiple interactions
ISO 2,4-Dinitrophenol affects the localization of APP protein
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]
CTD PMID:18949129 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of CIDEA mRNA CTD PMID:24872412 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO 2,4-Dinitrophenol results in increased expression of COX4I1 mRNA CTD PMID:11784294 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
ISO
EXP
2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
2,4-Dinitrophenol results in increased activity of CYP1A1 protein
CTD PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of DIO2 mRNA CTD PMID:24872412 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of FGF21 mRNA CTD PMID:24872412 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor multiple interactions ISO 2,4-Dinitrophenol inhibits the reaction [GNRHR protein results in increased transport of deslorelin] CTD PMID:15212170 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
JBrowse link
G Gpx4 glutathione peroxidase 4 decreases response to substance EXP GPX4 protein results in decreased susceptibility to 2,4-Dinitrophenol CTD PMID:19818760 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO 2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium]; Glyburide inhibits the reaction [2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium]] CTD PMID:15949470 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Lep leptin multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of LEP mRNA CTD PMID:24872412 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO 2,4-Dinitrophenol results in increased expression of NRF1 mRNA CTD PMID:11784294 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Prdm16 PR/SET domain 16 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of PRDM16 mRNA CTD PMID:24872412 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of SCD1 mRNA CTD PMID:24872412 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO 2,4-Dinitrophenol inhibits the reaction [SLC16A1 protein results in increased uptake of Lactic Acid] CTD PMID:15804185 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO 2,4-Dinitrophenol inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712
JBrowse link
G Smn1 survival of motor neuron 1, telomeric increases expression ISO 2,4-Dinitrophenol results in increased expression of SMN1 mRNA alternative form CTD PMID:17064354 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO 2,4-Dinitrophenol results in increased expression of SRXN1 protein CTD PMID:27358234 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions ISO [2,4-Dinitrophenol co-treated with Dietary Fats] affects the expression of UCP1 mRNA CTD PMID:24872412 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        inhibitor 18575
          oxidative phosphorylation inhibitor 20
            2,4-dinitrophenol + 20
            N-tert-butyl-N'-(2,6-diisopropyl-4-phenoxyphenyl)methanediimine 0
            diafenthiuron + 0
            diafenthiuron-S-oxide 0
paths to the root