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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acifluorfen
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Accession:CHEBI:73172 term browser browse the term
Definition:A member of the class of benzoic acids that is 2-nitrobenzoic acid in which the hydrogen at position 5 is replaced by a 2-chloro-4-(trifluoromethyl)phenoxy group. It is a herbicide used for the post-emergence control of a variety of annual broadleaf weeds.
Synonyms:exact_synonym: 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid
 related_synonym: 2-nitro-5-(2-chloro-4-(trifluoromethyl)phenoxy)benzoic acid;   5-(2-Chloro-alpha,alpha,alpha-trifluoro-p-tolyloxy)-2-nitrobenzoic acid;   Blazer;   Formula=C14H7ClF3NO5;   InChI=1S/C14H7ClF3NO5/c15-10-5-7(14(16,17)18)1-4-12(10)24-8-2-3-11(19(22)23)9(6-8)13(20)21/h1-6H,(H,20,21);   InChIKey=NUFNQYOELLVIPL-UHFFFAOYSA-N;   SMILES=OC(=O)c1cc(Oc2ccc(cc2Cl)C(F)(F)F)ccc1[N+]([O-])=O;   acifluorfene
 xref: CAS:50594-66-6;   HMDB:HMDB0037112;   KEGG:C22041
 xref_mesh: MESH:C018425
 xref: MetaCyc:ACIFLUORFEN;   PDBeChem:ACJ;   PMID:11455817;   PMID:11600024;   PMID:11837431;   PMID:2211482;   PMID:2813868;   PMID:7697001;   PMID:8089433;   PMID:8761738;   PPDB:819;   Patent:EP0706993;   Reaxys:2953865;   Wikipedia:Acifluorfen



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acifluorfen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases response to substance ISO BCL2 protein results in decreased susceptibility to acifluorfen CTD PMID:15475374 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
ISO NR1I3 gene mutant form inhibits the reaction [acifluorfen results in increased expression of CYP2B10 mRNA] CTD PMID:26928356 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases response to substance
ISO NR1I3 gene mutant form inhibits the reaction [acifluorfen results in increased expression of CYP2B10 mRNA]
NR1I3 gene mutant form results in decreased susceptibility to acifluorfen
CTD PMID:26928356 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO acifluorfen results in increased expression of PARP1 protein modified form CTD PMID:25944804 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ppox protoporphyrinogen oxidase decreases activity ISO acifluorfen results in decreased activity of PPOX protein CTD PMID:7697001 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19803
    role 19779
      application 19652
        agrochemical 16258
          acifluorfen 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19803
    subatomic particle 19801
      composite particle 19801
        hadron 19830
          baryon 19830
            nucleon 19830
              atomic nucleus 19830
                atom 19801
                  main group element atom 19780
                    p-block element atom 19780
                      carbon group element atom 19728
                        carbon atom 19725
                          organic molecular entity 19725
                            heteroorganic entity 19479
                              organochalcogen compound 19214
                                organooxygen compound 19129
                                  carbon oxoacid 18617
                                    carboxylic acid 18578
                                      aromatic carboxylic acid 12246
                                        benzoic acids 12221
                                          acifluorfen 5
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