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G
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Eif4a1
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eukaryotic translation initiation factor 4A1
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multiple interactions
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ISO
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[6-Aminonicotinamide co-treated with spautin-1] results in increased degradation of EIF4A1 protein
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CTD |
PMID:30821613 |
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NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,883,093...54,888,602
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G
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Fgf2
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fibroblast growth factor 2
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multiple interactions increases expression
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ISO
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IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of FGF2 protein]
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CTD |
PMID:12898533 |
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NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
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G
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Gsk3b
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glycogen synthase kinase 3 beta
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multiple interactions
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ISO
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6-Aminonicotinamide inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]
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CTD |
PMID:25246272 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
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G
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Hmox1
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heme oxygenase 1
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multiple interactions
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ISO
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6-Aminonicotinamide inhibits the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
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CTD |
PMID:25246272 |
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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G
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Il1b
|
interleukin 1 beta
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multiple interactions increases expression
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ISO
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IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of IL1B protein]
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CTD |
PMID:12898533 |
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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G
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Il6
|
interleukin 6
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multiple interactions increases expression
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ISO
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6-Aminonicotinamide promotes the reaction [IL6 protein results in increased expression of MT1 protein]; 6-Aminonicotinamide promotes the reaction [IL6 protein results in increased expression of MT2 protein]; IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of FGF2 protein]; IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of IL1B protein]; IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of NTF3 protein]; IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of TGFB1 protein]; IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of TNF protein] 6-Aminonicotinamide results in increased expression of IL6 protein
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CTD |
PMID:12898533 |
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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G
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Mt1a
|
metallothionein 1A
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increases expression multiple interactions decreases response to substance
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ISO
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6-Aminonicotinamide results in increased expression of MT1 protein 6-Aminonicotinamide promotes the reaction [IL6 protein results in increased expression of MT1 protein] MT1 protein results in decreased susceptibility to 6-Aminonicotinamide
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CTD |
PMID:11835189 PMID:12898533 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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G
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Mt2
|
metallothionein 2
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multiple interactions increases expression decreases response to substance
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ISO
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6-Aminonicotinamide promotes the reaction [IL6 protein results in increased expression of MT2 protein] 6-Aminonicotinamide results in increased expression of MT2 protein MT2 protein results in decreased susceptibility to 6-Aminonicotinamide
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CTD |
PMID:11835189 PMID:12898533 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,837,927...10,838,709
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G
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Mt3
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metallothionein 3
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increases expression
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ISO
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6-Aminonicotinamide results in increased expression of MT3 protein
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CTD |
PMID:10785446 |
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NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,854,677...10,856,080
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G
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Ntf3
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neurotrophin 3
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increases expression multiple interactions
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ISO
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6-Aminonicotinamide results in increased expression of NTF3 protein IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of NTF3 protein]
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CTD |
PMID:12898533 |
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NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:160,600,770...160,676,349
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G
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Parp1
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poly (ADP-ribose) polymerase 1
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multiple interactions
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ISO
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6-Aminonicotinamide inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]
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CTD |
PMID:25246272 |
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NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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G
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Sox17
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SRY-box transcription factor 17
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decreases localization
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ISO
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6-Aminonicotinamide results in decreased localization of SOX17 protein
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CTD |
PMID:24154490 |
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NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:19,814,360...19,819,854
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G
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Tgfb1
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transforming growth factor, beta 1
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multiple interactions increases expression
|
ISO
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IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of TGFB1 protein]
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CTD |
PMID:12898533 |
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NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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G
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Tnf
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tumor necrosis factor
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increases expression multiple interactions
|
ISO
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6-Aminonicotinamide results in increased expression of TNF protein IL6 protein promotes the reaction [6-Aminonicotinamide results in increased expression of TNF protein]
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CTD |
PMID:12898533 |
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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