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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,8-diaminooctane
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Accession:CHEBI:73112 term browser browse the term
Definition:An alkane-alpha,omega-diamine in which the two amino groups are separated by eight methylene groups.
Synonyms:exact_synonym: octane-1,8-diamine
 related_synonym: 1,8-Octamethylenediamine;   1,8-Octylenediamine;   1,8-octanediamine;   Formula=C8H20N2;   InChI=1S/C8H20N2/c9-7-5-3-1-2-4-6-8-10/h1-10H2;   InChIKey=PWGJDPKCLMLPJW-UHFFFAOYSA-N;   Octamethylenediamine;   SMILES=NCCCCCCCCN;   alpha,omega-diaminooctane
 xref: CAS:373-44-4;   MetaCyc:18-DIAMINOOCTANE;   Reaxys:1735426


show annotations for term's descendants           Sort by:
WIN 18446 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases activity EXP
ISO		 N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine results in decreased activity of ALDH1A2 protein CTD PMID:12547725 PMID:30958995 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Hopx HOP homeobox multiple interactions ISO [nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in decreased expression of HOPX mRNA; [nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in decreased expression of HOPX protein CTD PMID:30995255 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909 		JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in increased expression of ID2 mRNA CTD PMID:30995255 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Pdpn podoplanin multiple interactions ISO [nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in decreased expression of PDPN mRNA; [nitrofen co-treated with N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine] results in decreased expression of PDPN protein CTD PMID:30995255 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      biological role 19722
        xenobiotic 18642
          octane 2752
            1,8-diaminooctane 5
              WIN 18446 5
              guazatine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    main group molecular entity 19698
                      s-block molecular entity 19554
                        hydrogen molecular entity 19546
                          hydrides 19022
                            inorganic hydride 17950
                              pnictogen hydride 17936
                                nitrogen hydride 17835
                                  azane 17621
                                    ammonia 17620
                                      organic amino compound 17620
                                        polyamine 8326
                                          diamine 8254
                                            primary diamine 5688
                                              alkane-alpha,omega-diamine 3768
                                                1,8-diaminooctane 5
                                                  WIN 18446 5
                                                  guazatine 0
paths to the root