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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,8-diaminooctane
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Accession:CHEBI:73112 term browser browse the term
Definition:An alkane-alpha,omega-diamine in which the two amino groups are separated by eight methylene groups.
Synonyms:exact_synonym: octane-1,8-diamine
 related_synonym: 1,8-Octamethylenediamine;   1,8-Octylenediamine;   1,8-octanediamine;   Formula=C8H20N2;   InChI=1S/C8H20N2/c9-7-5-3-1-2-4-6-8-10/h1-10H2;   InChIKey=PWGJDPKCLMLPJW-UHFFFAOYSA-N;   Octamethylenediamine;   SMILES=NCCCCCCCCN;   alpha,omega-diaminooctane
 xref: CAS:373-44-4;   MetaCyc:18-DIAMINOOCTANE;   Reaxys:1735426


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WIN 18446 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases activity EXP
ISO
N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine results in decreased activity of ALDH1A2 protein CTD PMID:12547725, PMID:30958995 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        xenobiotic 18413
          octane 2170
            1,8-diaminooctane 2
              WIN 18446 2
              guazatine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      s-block molecular entity 19461
                        hydrogen molecular entity 19452
                          hydrides 18707
                            inorganic hydride 17430
                              pnictogen hydride 17402
                                nitrogen hydride 17243
                                  azane 16960
                                    ammonia 16959
                                      organic amino compound 16958
                                        polyamine 8136
                                          diamine 8063
                                            primary diamine 5628
                                              alkane-alpha,omega-diamine 3736
                                                1,8-diaminooctane 2
                                                  WIN 18446 2
                                                  guazatine 0
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