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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
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Accession:CHEBI:72999 term browser browse the term
Definition:A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
Synonyms:exact_synonym: (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
 related_synonym: 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine;   1,2-Dipalmitoyl-L-lecithin;   1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine;   1,2-dipalmitoyl-sn-glycero-3-phosphocholine;   1,2-dipalmitoylphosphatidylcholine;   1-16:0-2-16:0-phosphatidylcholine;   16:0-16:0-PC;   Dipalmitoyl phosphatidylcholine;   Formula=C40H80NO8P;   GPC(16:0/16:0);   GPCho 16:0/16:0;   InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1;   InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N;   PC(32:0);   Palmitato de colfoscerilo;   Phosphatidylcholine(32:0);   SMILES=CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC;   colfosceril palmitate;   colfoscerili palmitas;   dipalmitoyl-GPC;   dipalmitoylphosphatidylcholine;   palmitate de colfosceril;   phosphatidylcholine 16:0/16:0
 alt_id: CHEBI:73797;   CHEBI:77026
 xref: CAS:2644-64-6;   CAS:63-89-8;   HMDB:HMDB0000564;   LIPID_MAPS_instance:LMGP01010564
 xref_mesh: MESH:D015060
 xref: MetaCyc:1-2-DIPALMITOYLPHOSPHATIDYLCHOLINE;   PDBeChem:PCF;   PMID:12950167;   PMID:22888753;   Reaxys:1917966;   Reaxys:5799515


show annotations for term's descendants           Sort by:
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO 1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein] CTD PMID:19041333 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Prnp prion protein multiple interactions
affects folding		 ISO Copper affects the reaction [1,2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19896
      chemical role 19512
        emulsifier 5173
          surfactant 5173
            1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    p-block element atom 19867
                      chalcogen 19616
                        oxygen atom 19589
                          oxygen molecular entity 19589
                            hydroxides 19384
                              oxoacid 18756
                                pnictogen oxoacid 13138
                                  phosphorus oxoacid 12392
                                    phosphoric acids 11426
                                      phosphoric acid 11426
                                        phosphoric acid derivative 11235
                                          phosphate 11234
                                            organic phosphate 11234
                                              phospholipid 312
                                                glycerophospholipid 211
                                                  glycerophosphocholine 124
                                                    phosphatidylcholine 82
                                                      1,2-diacyl-sn-glycero-3-phosphocholine 23
                                                        phosphatidylcholine 32:0 2
                                                          1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
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