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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
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Accession:CHEBI:72999 term browser browse the term
Definition:A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
Synonyms:exact_synonym: (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
 related_synonym: 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine;   1,2-Dipalmitoyl-L-lecithin;   1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine;   1,2-dipalmitoyl-sn-glycero-3-phosphocholine;   1,2-dipalmitoylphosphatidylcholine;   1-16:0-2-16:0-phosphatidylcholine;   16:0-16:0-PC;   Dipalmitoyl phosphatidylcholine;   Formula=C40H80NO8P;   GPC(16:0/16:0);   GPCho 16:0/16:0;   InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1;   InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N;   PC(32:0);   Palmitato de colfoscerilo;   Phosphatidylcholine(32:0);   SMILES=CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC;   colfosceril palmitate;   colfoscerili palmitas;   dipalmitoyl-GPC;   dipalmitoylphosphatidylcholine;   palmitate de colfosceril;   phosphatidylcholine 16:0/16:0
 alt_id: CHEBI:73797;   CHEBI:77026
 xref: CAS:2644-64-6;   CAS:63-89-8;   HMDB:HMDB0000564;   LIPID_MAPS_instance:LMGP01010564
 xref_mesh: MESH:D015060
 xref: MetaCyc:1-2-DIPALMITOYLPHOSPHATIDYLCHOLINE;   PDBeChem:PCF;   PMID:12950167;   PMID:22888753;   Reaxys:1917966;   Reaxys:5799515


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1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO 1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein] CTD PMID:19041333 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G Prnp prion protein multiple interactions
affects folding
ISO Copper affects the reaction [1,2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      chemical role 19332
        emulsifier 4416
          surfactant 4416
            1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      chalcogen 19456
                        oxygen atom 19432
                          oxygen molecular entity 19432
                            hydroxides 19171
                              oxoacid 18485
                                pnictogen oxoacid 10688
                                  phosphorus oxoacid 9669
                                    phosphoric acids 8466
                                      phosphoric acid 8466
                                        phosphoric acid derivative 8171
                                          phosphate 8171
                                            organic phosphate 8170
                                              phospholipid 302
                                                glycerophospholipid 203
                                                  glycerophosphocholine 118
                                                    phosphatidylcholine 81
                                                      1,2-diacyl-sn-glycero-3-phosphocholine 23
                                                        phosphatidylcholine 32:0 2
                                                          1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
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