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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
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Accession:CHEBI:72999 term browser browse the term
Definition:A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
Synonyms:exact_synonym: (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate;   (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
 related_synonym: 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine;   1,2-Dipalmitoyl-L-lecithin;   1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine;   1,2-dipalmitoyl-sn-glycero-3-phosphocholine;   1,2-dipalmitoylphosphatidylcholine;   1-16:0-2-16:0-phosphatidylcholine;   16:0-16:0-PC;   Dipalmitoyl phosphatidylcholine;   Formula=C40H80NO8P;   GPC(16:0/16:0);   GPCho 16:0/16:0;   InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1;   InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N;   PC(32:0);   Palmitato de colfoscerilo;   Phosphatidylcholine(32:0);   SMILES=CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC;   colfosceril palmitate;   colfoscerili palmitas;   dipalmitoyl-GPC;   dipalmitoylphosphatidylcholine;   palmitate de colfosceril;   phosphatidylcholine 16:0/16:0
 alt_id: CHEBI:44843;   CHEBI:73797;   CHEBI:77026
 xref: CAS:2644-64-6;   CAS:63-89-8;   Drug_Central:730;   HMDB:HMDB0000564;   LIPID_MAPS_instance:LMGP01010564
 xref_mesh: MESH:D015060
 xref: MetaCyc:1-2-DIPALMITOYLPHOSPHATIDYLCHOLINE;   PDBeChem:PCF;   PMID:12950167;   PMID:22888753;   Reaxys:1917966;   Reaxys:5799515;   Wikipedia:Dipalmitoylphosphatidylcholine
 cyclic_relationship: is_conjugate_base_of CHEBI:40265



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1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO 1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein] CTD PMID:19041333 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G Prnp prion protein multiple interactions
affects folding
ISO Copper affects the reaction [1,2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      chemical role 19462
        emulsifier 7510
          surfactant 7510
            1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      chalcogen 19555
                        oxygen atom 19528
                          oxygen molecular entity 19528
                            hydroxides 19335
                              oxoacid 18769
                                pnictogen oxoacid 14903
                                  phosphorus oxoacid 14492
                                    phosphoric acids 13930
                                      phosphoric acid 13930
                                        phosphoric acid derivative 13836
                                          phosphate 13835
                                            organic phosphate 13835
                                              phospholipid 316
                                                glycerophospholipid 211
                                                  glycerophosphocholine 124
                                                    phosphatidylcholine 82
                                                      1,2-diacyl-sn-glycero-3-phosphocholine 23
                                                        phosphatidylcholine 32:0 2
                                                          1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
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