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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-methyltryptophan
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Accession:CHEBI:72821 term browser browse the term
Definition:A tryptophan derivative that is tryptophan carrying a single methyl substituent at position 1 on the indole.
Synonyms:related_synonym: 1-methyl-DL-tryptophan;   Formula=C12H14N2O2;   InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16);   InChIKey=ZADWXFSZEAPBJS-UHFFFAOYSA-N;   N-methyl-DL-tryptophan;   N-methyltryptophan;   SMILES=Cn1cc(CC(N)C(O)=O)c2ccccc12
 xref: CAS:26988-72-7
 xref_mesh: MESH:C525396
 xref: PMID:18195714;   PMID:19307751;   PMID:19461669;   PMID:20424892;   PMID:20435158;   PMID:21526853;   PMID:22068654;   PMID:22131334;   PMID:22184722;   PMID:22294267;   PMID:22320717;   PMID:22504306;   PMID:22527253;   PMID:22594922;   PMID:22615663;   Reaxys:20071;   Wikipedia:1-Methyltryptophan



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1-methyltryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of AHR protein] CTD PMID:35687267 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein] CTD PMID:35687267 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein] CTD PMID:35687267 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of E2F1 protein] CTD PMID:35687267 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETV6 protein] CTD PMID:35687267 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 decreases activity ISO 1-methyltryptophan results in decreased activity of IDO2 protein CTD PMID:32289347 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MKI67 protein] CTD PMID:35687267 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of POU5F1 protein] CTD PMID:35687267 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of RUNX1 protein] CTD PMID:35687267 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase multiple interactions ISO 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of TDO2 protein] CTD PMID:35687267 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link

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              1-methyltryptophan 10
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                  main group element atom 19866
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                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        amino acid 15961
                                          polar amino acid 11709
                                            tryptophan 34
                                              tryptophan derivative 19
                                                1-methyltryptophan 10
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