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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:aryl hydrocarbon receptor agonist
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Accession:CHEBI:72768 term browser browse the term
Definition:An agonist that binds to and activates aryl hydrocarbon receptors (AhRs).
Synonyms:related_synonym: AHR agonist;   AhR agonists;   aryl hydrocarbon receptor agonists


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1,2-naphthoquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
affects localization		 ISO 1,2-naphthoquinone promotes the reaction [AHR protein binds to ARNT protein]; 1,2-naphthoquinone promotes the reaction [AHR protein binds to CYP1A1 enhancer]; AHR protein affects the reaction [1,2-naphthoquinone results in increased expression of CYP1A1 mRNA]
1,2-naphthoquinone results in increased expression of and affects the localization of AHR protein
1,2-naphthoquinone affects the localization of AHR protein		 CTD PMID:26558468 PMID:27853106 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of 1,2-naphthoquinone CTD PMID:10510318 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction ISO AKR1B1 protein results in increased reduction of 1,2-naphthoquinone CTD PMID:10510318 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction ISO AKR7A2 protein results in increased reduction of 1,2-naphthoquinone CTD PMID:10510318 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Alb albumin affects binding ISO 1,2-naphthoquinone binds to ALB protein CTD PMID:12385719 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO 1,2-naphthoquinone results in increased expression of ALDH3A1 mRNA CTD PMID:26558468 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO 1,2-naphthoquinone promotes the reaction [AHR protein binds to ARNT protein] CTD PMID:26558468 PMID:27853106 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [1,2-naphthoquinone results in increased expression of CXCL8 mRNA]; CAT protein inhibits the reaction [1,2-naphthoquinone results in increased expression of PTGS2 mRNA]; CAT protein promotes the reaction [1,2-naphthoquinone results in increased expression of HMOX1 mRNA] CTD PMID:21997482 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions ISO [S-Nitrosoglutathione binds to CBR1 protein] promotes the reaction [CBR1 protein results in increased metabolism of 1,2-naphthoquinone] CTD PMID:23295225 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO 1,2-naphthoquinone binds to and results in decreased activity of CREB1 protein CTD PMID:21530497 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO 1,2-naphthoquinone promotes the reaction [AHR protein binds to CYP1A1 enhancer]; 1,2-naphthoquinone promotes the reaction [POLR2A protein binds to CYP1A1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,2-naphthoquinone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [1,2-naphthoquinone results in increased expression of CYP1A1 mRNA] CTD PMID:26558468 PMID:26656082 PMID:27853106 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase increases metabolic processing
multiple interactions		 ISO DCXR protein results in increased metabolism of 1,2-naphthoquinone
1,2-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]		 CTD PMID:28595002 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases reduction ISO DHRS7 protein results in increased reduction of 1,2-naphthoquinone CTD PMID:24246760 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation		 ISO 1,2-naphthoquinone results in increased phosphorylation of and results in increased activity of EGFR protein; 1,4-naphthoquinone promotes the reaction [1,2-naphthoquinone results in increased phosphorylation of EGFR protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [1,4-naphthoquinone promotes the reaction [1,2-naphthoquinone results in increased phosphorylation of EGFR protein]] CTD PMID:24067727 PMID:33814511 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases stability ISO 1,2-naphthoquinone results in increased stability of FOS protein CTD PMID:24067727 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases activity
affects binding
multiple interactions		 ISO 1,2-naphthoquinone results in decreased activity of GAPDH protein
1,2-naphthoquinone binds to GAPDH protein
[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone binds to GAPDH protein]; [Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone results in decreased activity of GAPDH protein]		 CTD PMID:21827172 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO CAT protein promotes the reaction [1,2-naphthoquinone results in increased expression of HMOX1 mRNA] CTD PMID:21997482 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of IKBKB protein] CTD PMID:21139339 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects response to substance
increases metabolic processing		 ISO KEAP1 protein affects the susceptibility to 1,2-naphthoquinone
1,2-naphthoquinone results in increased metabolism of KEAP1 protein		 CTD PMID:21384861 PMID:25807370 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [1,2-naphthoquinone results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [1,2-naphthoquinone results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[1,2-naphthoquinone co-treated with 1,4-naphthoquinone] results in increased phosphorylation of MAPK1 protein]; [1,2-naphthoquinone co-treated with 1,4-naphthoquinone] results in increased phosphorylation of MAPK1 protein CTD PMID:24067727 PMID:33814511 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO 1,2-naphthoquinone results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [1,2-naphthoquinone results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [1,2-naphthoquinone results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [[1,2-naphthoquinone co-treated with 1,4-naphthoquinone] results in increased phosphorylation of MAPK3 protein]; [1,2-naphthoquinone co-treated with 1,4-naphthoquinone] results in increased phosphorylation of MAPK3 protein		 CTD PMID:24067727 PMID:33814511 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases activity
affects response to substance		 ISO NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to 1,2-naphthoquinone]
1,2-naphthoquinone results in increased activity of NFE2L2 protein
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to 1,2-naphthoquinone; NFE2L2 protein affects the susceptibility to 1,2-naphthoquinone		 CTD PMID:19303893 PMID:20932822 PMID:21384861 PMID:21651925 PMID:25807370 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:21139339 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide] CTD PMID:21139339 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases reduction
increases expression		 ISO NQO1 protein results in increased reduction of 1,2-naphthoquinone
1,2-naphthoquinone results in increased expression of NQO1 mRNA		 CTD PMID:21384861 PMID:26558468 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Polr2a RNA polymerase II subunit A multiple interactions ISO 1,2-naphthoquinone promotes the reaction [POLR2A protein binds to CYP1A1 protein] CTD PMID:26558468 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions ISO 1,2-naphthoquinone binds to and results in decreased activity of PRDX6 protein CTD PMID:22129745 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO 1,2-naphthoquinone results in increased expression of PTGS2 mRNA
CAT protein inhibits the reaction [1,2-naphthoquinone results in increased expression of PTGS2 mRNA]		 CTD PMID:21997482 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 decreases activity
multiple interactions		 ISO 1,2-naphthoquinone results in decreased activity of PTPN1 protein
1,2-naphthoquinone promotes the reaction [1,4-naphthoquinone results in increased metabolism of and results in decreased activity of PTPN1 protein]		 CTD PMID:24067727 PMID:33814511 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 1,2-naphthoquinone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased localization of and results in increased activity of RELA protein] CTD PMID:21139339 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions EXP [1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR1 mRNA; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR1 mRNA] CTD PMID:19399481 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tacr2 tachykinin receptor 2 multiple interactions EXP [1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR2 mRNA; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR2 mRNA] CTD PMID:19399481 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
affects activity		 ISO 1,2-naphthoquinone binds to and results in decreased activity of TOP2A protein
1,2-naphthoquinone affects the activity of TOP2A protein		 CTD PMID:22218491 PMID:33760604 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Top2b DNA topoisomerase II beta affects activity ISO 1,2-naphthoquinone affects the activity of TOP2B protein CTD PMID:33760604 NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO 1,2-naphthoquinone results in increased activity of TRPA1 protein CTD PMID:21591660 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP [1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TRPV1 mRNA; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TRPV1 mRNA] CTD PMID:19399481 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity ISO 1,2-naphthoquinone results in increased activity of TRPV3 protein CTD PMID:29658714 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO 1,2-naphthoquinone results in increased metabolism of and results in decreased activity of UCHL1 protein; Glutathione inhibits the reaction [1,2-naphthoquinone results in increased metabolism of and results in decreased activity of UCHL1 protein] CTD PMID:24582816 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
3-methylcholanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Methylcholanthrene results in decreased expression of ABCA1 mRNA CTD PMID:20713471 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Methylcholanthrene results in increased expression of ABCB1 mRNA; Methylcholanthrene results in increased expression of ABCB1A mRNA CTD PMID:11096091 PMID:27160211 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of ABCB1B mRNA
Methylcholanthrene promotes the reaction [TRP53 protein binds to ABCB1B promoter]		 CTD PMID:11096091 PMID:20713471 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ABCB4 mRNA CTD PMID:25926378 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Methylcholanthrene results in increased expression of ABCB6 mRNA CTD PMID:22761424 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Methylcholanthrene results in increased expression of ABCC3 mRNA CTD PMID:19118567 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Methylcholanthrene results in increased expression of ABCC4 mRNA; Methylcholanthrene results in increased expression of ABCC4 protein CTD PMID:20395535 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
affects response to substance		 ISO AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR]
Methylcholanthrene results in increased expression of ABCG2; Methylcholanthrene results in increased expression of ABCG2 mRNA; Methylcholanthrene results in increased expression of ABCG2 mRNA alternative form; Methylcholanthrene results in increased expression of ABCG2 protein
ABCG2 5' UTR affects the susceptibility to Methylcholanthrene		 CTD PMID:20804740 PMID:23081912 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO Methylcholanthrene results in decreased expression of ABI3BP mRNA CTD PMID:20713471 NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929 		JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ACOX2 promoter] CTD PMID:20348232 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter] CTD PMID:20348232 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression ISO Methylcholanthrene results in decreased expression of ACTA1 mRNA CTD PMID:29554273 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Methylcholanthrene results in decreased expression of ACTA2 mRNA CTD PMID:20713471 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression ISO Methylcholanthrene results in increased expression of ADAM8 mRNA CTD PMID:20713471 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases acetylation
increases methylation
multiple interactions
increases expression		 EXP Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter
Methylcholanthrene results in increased methylation of ADAMTS1 promoter
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of ADAMTS1 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ADAMTS1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of ADAMTS1 promoter]
Methylcholanthrene results in increased expression of ADAMTS1 mRNA		 CTD PMID:29094188 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 decreases expression ISO Methylcholanthrene results in decreased expression of ADAMTS12 mRNA CTD PMID:20713471 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 decreases expression ISO Methylcholanthrene results in decreased expression of ADAMTS2 mRNA CTD PMID:20713471 NCBI chr10:34,920,992...35,126,465
Ensembl chr10:34,921,049...35,123,821 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 increases expression ISO Methylcholanthrene results in increased expression of ADAMTS4 mRNA CTD PMID:20713471 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065 		JBrowse link
G Adcy7 adenylate cyclase 7 increases expression ISO Methylcholanthrene results in increased expression of ADCY7 mRNA CTD PMID:20713471 PMID:29554273 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311 		JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ADGRF1 promoter] CTD PMID:20348232 NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704 		JBrowse link
G Adgrg5 adhesion G protein-coupled receptor G5 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ADGRG5 mRNA; [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of ADGRG5 mRNA CTD PMID:25926378 NCBI chr19:10,074,787...10,098,640
Ensembl chr19:10,079,375...10,097,214 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Methylcholanthrene results in decreased expression of ADH4 mRNA CTD PMID:27055685 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) decreases expression ISO Methylcholanthrene results in decreased expression of ADH6 mRNA CTD PMID:27055685 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO Methylcholanthrene results in increased expression of ADH7 mRNA CTD PMID:20713471 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA CTD PMID:23519560 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adora3 adenosine A3 receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA CTD PMID:23519560 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA		 CTD PMID:20348232 PMID:23519560 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to AGR2 promoter] CTD PMID:20348232 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Ahr aryl hydrocarbon receptor increases response to substance
increases expression
decreases expression
affects binding
multiple interactions
increases activity
increases localization
affects response to substance
increases degradation
affects localization		 ISO
EXP		 AHR protein results in increased susceptibility to Methylcholanthrene; AHR results in increased susceptibility to Methylcholanthrene
Methylcholanthrene results in increased expression of AHR mRNA
Methylcholanthrene results in decreased expression of AHR protein
Methylcholanthrene binds to AHR protein
[Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]
[Methylcholanthrene binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [Methylcholanthrene binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; AHR affects the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; AHR affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in decreased expression of CYP3A11 mRNA]; AHR protein affects the reaction [Methylcholanthrene affects the expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of FMO3 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of XDH protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased localization of AHR protein]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Methylcholanthrene binds to AHR protein]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Methylcholanthrene binds to and affects the localization of AHR protein; Methylcholanthrene binds to and results in increased activity of AHR protein; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene results in increased activity of and results in increased localization of AHR protein; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Raloxifene Hydrochloride inhibits the reaction [Methylcholanthrene binds to AHR protein]
Methylcholanthrene results in increased localization of AHR protein
AHR affects the susceptibility to Methylcholanthrene
Methylcholanthrene results in increased degradation of AHR protein
Methylcholanthrene results in increased expression of AHR protein
[AHR gene mutant form binds to ARNT protein] which results in decreased susceptibility to Methylcholanthrene; [chrysin co-treated with Methylcholanthrene] affects the activity of AHR protein; [Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein; [Methylcholanthrene co-treated with Oxygen deficiency] results in increased expression of AHR mRNA; [Methylcholanthrene co-treated with pirinixic acid] results in increased expression of AHR protein; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of IL1B mRNA; [Quercetin co-treated with Methylcholanthrene] affects the activity of AHR protein; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP3A5 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Methylcholanthrene binds to and results in increased activity of AHR protein; Methylcholanthrene binds to and results in increased activity of AHR protein polymorphism; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR]; Methylcholanthrene promotes the reaction [AHR protein binds to ACOX2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ADGRF1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to AGR2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to AKAP13 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANGPTL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD13C promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD30B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP22 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP35 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARL3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARMC12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BAMBI promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BBX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BCL6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BPIFA2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein]; Methylcholanthrene promotes the reaction [AHR protein binds to BRWD1-AS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C16ORF74 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF19 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF36 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CA12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CA8 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CACNA1B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CAST promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC144NL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC57 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCN5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CD55 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CEACAM3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CENPL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CEP70 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CFAP61 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CHPT1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CHRDL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CILK1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CISD1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLDN17 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLK3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLPSL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to COLCA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to COX4I1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CRKL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CTNNA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CUEDC1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYB5B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DEGS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DIAPH1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DTNA promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DUSP14 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EHD3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EPS15 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EXOSC9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FOXN1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FREM2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GDPD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GPHB5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GREB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GRIK4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GSDMC promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to H2BC1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to H2BC21 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HCRTR2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HDAC11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HOXC11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HSBP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IDH2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IER3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGFBPL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to INHBC promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IRF2BPL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ISOC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ITPR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JPH1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KATNAL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KCTD16 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KCTD3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KIR2DL4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KLF9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KRT75 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LGALS8 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LGI1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LIF promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LIMA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LINC00173 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LRP11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LSM5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LY6E promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MAPKAP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MBNL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MGST2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MLLT6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MLPH promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MPI promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MRTFB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MS4A7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MTCL3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MYOF promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MYOM2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NBPF10 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NBPF3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NDST1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NELFCD promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NFE2L2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NMRAL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NXT2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to OSBPL10 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to OTUB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PAXBP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PCOLCE2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PDCD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PHACTR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PIGP promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PIK3R1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PLEKHA6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to POGZ promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to POTEB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PPIAL4A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRPS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PSG5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PSG9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PWWP3A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RABL2A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RALGAPA2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RANBP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBBP7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBM24 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBMS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBSN promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RERG promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RFFL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGPD5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGPD6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGS3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RHOBTB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RHOH promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RPL11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RTN3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RYR3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to S100P promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SAMD12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SCN3B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SIK3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC16A6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC22A23 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC44A1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLU7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SMAP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SMARCE1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SNAPIN promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOCS7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SORL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPON2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPRED1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPTLC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SS18 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to STARD13 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to STAT5B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SWSAP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SYCP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SYT12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TBL1XR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TEAD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to THBS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to THEM5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TIPARP promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM116 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM30A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM45B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM97 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMTC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TNK2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRERF1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM39 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM55 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM72 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRPV4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TTC3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to UBE2E1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to UMODL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VEZT promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VIPR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VSTM1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VWCE promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WBP1L promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WDR26 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WEE1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZBTB4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZCCHC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZMAT3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZMIZ1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF281 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF552 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF587 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF695 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF710 promoter]; Methylcholanthrene promotes the reaction [Nicardipine results in increased activity of AHR protein]; Methylcholanthrene results in increased activity of and results in increased degradation of AHR protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Resveratrol inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]
Methylcholanthrene affects the localization of AHR protein		 CTD PMID:1650214 PMID:1654865 PMID:1658612 PMID:1846074 PMID:2154949 More... NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions
increases expression		 ISO [Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA
Methylcholanthrene results in increased expression of AHRR mRNA		 CTD PMID:9887096 PMID:11423533 PMID:12655030 PMID:14672759 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Akap13 A-kinase anchoring protein 13 decreases expression
multiple interactions		 ISO Methylcholanthrene results in decreased expression of AKAP13 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to AKAP13 promoter]		 CTD PMID:20348232 PMID:20713471 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO Methylcholanthrene results in increased expression of AKR1A1 mRNA CTD PMID:9973208 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Methylcholanthrene results in increased expression of AKR1C1 mRNA CTD PMID:9973208 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases acetylation
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA] CTD PMID:29094188 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO Methylcholanthrene results in increased expression of ALCAM mRNA CTD PMID:20713471 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO
EXP		 Methylcholanthrene results in increased expression of ALDH3A1 mRNA CTD PMID:1416978 PMID:20713471 PMID:28601433 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Angptl2 angiopoietin-like 2 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of ANGPTL2 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to ANGPTL2 promoter]		 CTD PMID:20348232 PMID:20713471 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Ank2 ankyrin 2 decreases expression ISO Methylcholanthrene results in decreased expression of ANK2 mRNA CTD PMID:20713471 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator increases expression ISO Methylcholanthrene results in increased expression of ANK mRNA CTD PMID:20713471 NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187 		JBrowse link
G Ankrd13c ankyrin repeat domain 13C multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD13C promoter] CTD PMID:20348232 NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433 		JBrowse link
G Anln anillin, actin binding protein increases expression ISO Methylcholanthrene results in increased expression of ANLN mRNA CTD PMID:20713471 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538 		JBrowse link
G Anxa8 annexin A8 increases expression ISO Methylcholanthrene results in increased expression of ANXA8 mRNA CTD PMID:20713471 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression EXP Methylcholanthrene results in increased expression of APAF1 mRNA CTD PMID:23273579 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apcdd1 APC down-regulated 1 increases expression ISO Methylcholanthrene results in increased expression of APCDD1 mRNA CTD PMID:20713471 NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070 		JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP Methylcholanthrene results in decreased expression of APOA4 mRNA CTD PMID:11328961 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression EXP Methylcholanthrene results in decreased expression of APOC1 mRNA CTD PMID:11328961 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apod apolipoprotein D decreases expression ISO Methylcholanthrene results in decreased expression of APOD mRNA CTD PMID:20713471 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Aqp5 aquaporin 5 increases expression ISO
EXP		 Methylcholanthrene results in increased expression of AQP5 mRNA CTD PMID:20713471 PMID:26372666 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Areg amphiregulin increases expression ISO
EXP		 Methylcholanthrene results in increased expression of AREG mRNA CTD PMID:16257430 PMID:26372666 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arhgap11a Rho GTPase activating protein 11A increases expression ISO Methylcholanthrene results in increased expression of ARHGAP11A mRNA CTD PMID:20713471 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559 		JBrowse link
G Arhgap22 Rho GTPase activating protein 22 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of ARHGAP22 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP22 promoter]		 CTD PMID:20348232 PMID:20713471 NCBI chr16:8,473,806...8,631,552
Ensembl chr16:8,476,306...8,631,548 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP35 promoter] CTD PMID:20348232 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter] CTD PMID:20348232 NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARL3 promoter] CTD PMID:20348232 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820 		JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO Methylcholanthrene results in increased expression of ARL6IP5 mRNA CTD PMID:20713471 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Armc12 armadillo repeat containing 12 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARMC12 promoter] CTD PMID:20348232 NCBI chr20:6,587,859...6,598,355
Ensembl chr20:6,587,859...6,598,352 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
increases expression
increases localization		 ISO
EXP		 [AHR gene mutant form binds to ARNT protein] which results in decreased susceptibility to Methylcholanthrene; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [ARNT protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to SORL1 promoter]
Methylcholanthrene results in increased expression of ARNT mRNA
Methylcholanthrene results in increased localization of ARNT protein
Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]		 CTD PMID:11768231 PMID:19951702 PMID:20348232 PMID:20570689 PMID:21756928 More... NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Arrb1 arrestin, beta 1 increases expression ISO Methylcholanthrene results in increased expression of ARRB1 mRNA CTD PMID:29554273 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Art3 ADP-ribosyltransferase 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA CTD PMID:23519560 NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of ASCL1 mRNA CTD PMID:25926378 NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO Methylcholanthrene results in increased expression of ASF1B mRNA CTD PMID:20713471 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 increases expression ISO Methylcholanthrene results in increased expression of ASIC1 mRNA CTD PMID:20713471 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Methylcholanthrene results in increased expression of ASPM mRNA CTD PMID:20713471 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755 		JBrowse link
G Aspn asporin decreases expression ISO Methylcholanthrene results in decreased expression of ASPN mRNA CTD PMID:20713471 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Methylcholanthrene results in increased expression of ATAD2 mRNA CTD PMID:20713471 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression EXP Methylcholanthrene results in increased expression of ATOX1 mRNA CTD PMID:23273579 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA CTD PMID:23519560 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028 		JBrowse link
G Aurka aurora kinase A increases expression ISO Methylcholanthrene results in increased expression of AURKA mRNA CTD PMID:20713471 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B increases expression ISO Methylcholanthrene results in increased expression of AURKB mRNA CTD PMID:20713471 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Methylcholanthrene results in increased expression of BAD mRNA CTD PMID:23273579 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 increases expression ISO Methylcholanthrene results in increased expression of BAIAP2 mRNA CTD PMID:20713471 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to BAMBI promoter] CTD PMID:20348232 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
increases methylation
multiple interactions		 EXP Methylcholanthrene results in increased expression of BAX mRNA
Methylcholanthrene results in increased methylation of BAX promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of BAX mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of BAX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]		 CTD PMID:23273579 PMID:29094188 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbx BBX high mobility group box domain containing multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to BBX promoter] CTD PMID:20348232 NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251 		JBrowse link
G Bcas3 BCAS3, microtubule associated cell migration factor decreases expression ISO Methylcholanthrene results in decreased expression of BCAS3 mRNA CTD PMID:22100608 NCBI chr10:70,213,710...70,673,080
Ensembl chr10:70,214,098...70,673,080 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of BCL10 mRNA CTD PMID:25926378 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression		 EXP
ISO		 Methylcholanthrene results in increased expression of BCL2 mRNA
Methylcholanthrene results in decreased expression of BCL2 mRNA		 CTD PMID:23273579 PMID:35487396 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl6 BCL6, transcription repressor increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of BCL6 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to BCL6 promoter]		 CTD PMID:20348232 PMID:20713471 PMID:25926378 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO Methylcholanthrene results in decreased expression of BDH2 mRNA CTD PMID:20713471 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Methylcholanthrene results in increased expression of BIRC3 mRNA CTD PMID:29554273 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Methylcholanthrene results in increased expression of BIRC5 mRNA CTD PMID:20713471 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Methylcholanthrene results in increased expression of BMF mRNA CTD PMID:29554273 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmp15 bone morphogenetic protein 15 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of BMP15 mRNA CTD PMID:29094188 NCBI chr  X:16,169,123...16,174,187
Ensembl chr  X:16,169,123...16,174,187 		JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression EXP Methylcholanthrene results in decreased expression of BMP4 mRNA CTD PMID:29094188 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO Methylcholanthrene results in increased expression of BPGM mRNA CTD PMID:20713471 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Bpifa2 BPI fold containing family A, member 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to BPIFA2 promoter] CTD PMID:20348232 NCBI chr 3:142,493,379...142,501,343
Ensembl chr 3:142,493,379...142,501,337 		JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions
increases expression		 ISO Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein]
Methylcholanthrene results in increased expression of BRCA1 mRNA		 CTD PMID:18259752 PMID:20713471 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Bri3bp Bri3 binding protein increases expression ISO Methylcholanthrene results in increased expression of BRI3BP mRNA CTD PMID:25926378 NCBI chr12:31,176,742...31,188,563
Ensembl chr12:31,173,971...31,188,572 		JBrowse link
G Brip1 BRCA1 interacting helicase 1 increases expression ISO Methylcholanthrene results in increased expression of BRIP1 mRNA CTD PMID:20713471 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA CTD PMID:23519560 NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Methylcholanthrene results in increased expression of BTG2 mRNA CTD PMID:22100608 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO Methylcholanthrene results in increased expression of BUB1 mRNA CTD PMID:20713471 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Methylcholanthrene results in increased expression of BUB1B mRNA CTD PMID:20713471 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G C14h4orf19 similar to human chromosome 4 open reading frame 19 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF19 promoter] CTD PMID:20348232 NCBI chr14:44,387,386...44,478,344
Ensembl chr14:44,387,393...44,478,041 		JBrowse link
G C14h4orf36 similar to human chromosome 4 open reading frame 36 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF36 promoter] CTD PMID:20348232 NCBI chr14:6,058,581...6,065,848
Ensembl chr14:6,058,581...6,065,847 		JBrowse link
G C19h16orf74  similar to human chromosome 16 open reading frame 74 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to C16ORF74 promoter] CTD PMID:20348232 NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349 		JBrowse link
G C1qbp complement C1q binding protein multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of C1QBP mRNA CTD PMID:25926378 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G C3 complement C3 increases expression ISO Methylcholanthrene results in increased expression of C3 mRNA CTD PMID:16257430 PMID:29554273 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4a complement C4A multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA CTD PMID:23519560 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080 		JBrowse link
G C4b complement C4B (Chido blood group) multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA CTD PMID:23519560 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G C6 complement C6 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of C6 mRNA CTD PMID:25926378 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CACNA1B promoter] CTD PMID:20348232 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA CTD PMID:23519560 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cadm1 cell adhesion molecule 1 multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of CADM1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CADM1 gene CTD PMID:21163286 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Calb2 calbindin 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter] CTD PMID:20348232 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Calcrl calcitonin receptor like receptor decreases expression ISO Methylcholanthrene results in decreased expression of CALCRL mRNA CTD PMID:20713471 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Calm1 calmodulin 1 increases expression ISO Methylcholanthrene results in increased expression of CALM1 mRNA CTD PMID:20713471 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calr calreticulin increases expression
multiple interactions		 EXP Methylcholanthrene results in increased expression of CALR mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CALR mRNA]		 CTD PMID:29094188 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA CTD PMID:23519560 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO Methylcholanthrene results in increased expression of CAPG mRNA CTD PMID:20713471 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Caps calcyphosine increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of TNFRSF23 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of TNFRSF23 mRNA		 CTD PMID:20713471 PMID:25926378 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647 		JBrowse link
G Car12 carbonic anhydrase 12 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CA12 promoter] CTD PMID:20348232 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Car8 carbonic anhydrase 8 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CA8 promoter] CTD PMID:20348232 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase decreases expression ISO Methylcholanthrene results in decreased expression of CASK mRNA CTD PMID:20713471 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions		 ISO
EXP		 Methylcholanthrene results in increased expression of CASP3 mRNA
Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of and results in increased activity of CASP3 protein]		 CTD PMID:11323195 PMID:11999409 PMID:20713471 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases expression
increases methylation
multiple interactions		 EXP Methylcholanthrene results in increased expression of CASP9 mRNA
Methylcholanthrene results in increased methylation of CASP9 promoter
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of CASP9 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CASP9 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CASP9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]		 CTD PMID:23273579 PMID:29094188 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cast calpastatin multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CAST promoter] CTD PMID:20348232 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Ccdc57 coiled-coil domain containing 57 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CCDC57 promoter] CTD PMID:20348232 NCBI chr10:106,092,784...106,196,405
Ensembl chr10:106,092,947...106,196,077 		JBrowse link
G Ccdc6 coiled-coil domain containing 6 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CCDC6 promoter] CTD PMID:20348232 NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases expression ISO Methylcholanthrene results in decreased expression of CCL17 mRNA CTD PMID:29554273 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CCL19 mRNA CTD PMID:25926378 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Methylcholanthrene results in increased expression of CCL2 mRNA CTD PMID:20713471 PMID:23397585 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Methylcholanthrene results in decreased expression of CCL5 mRNA CTD PMID:20713471 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Methylcholanthrene results in increased expression of CCL7 mRNA CTD PMID:20713471 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Methylcholanthrene results in increased expression of CCN1 mRNA CTD PMID:20713471 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Methylcholanthrene results in increased expression of CCN3 mRNA CTD PMID:20713471 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ccn4 cellular communication network factor 4 decreases expression ISO Methylcholanthrene results in decreased expression of CCN4 mRNA CTD PMID:20713471 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Ccn5 cellular communication network factor 5 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of CCN5 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to CCN5 promoter]		 CTD PMID:20348232 PMID:20713471 NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO Methylcholanthrene results in increased expression of CCNA2 mRNA CTD PMID:20713471 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 increases expression ISO
EXP		 Methylcholanthrene results in increased expression of CCNB1 mRNA CTD PMID:20713471 PMID:26372666 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 increases expression
multiple interactions		 ISO
EXP		 Methylcholanthrene results in increased expression of CCNB2 mRNA
Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of CCNB2 mRNA]		 CTD PMID:20713471 PMID:26372666 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Methylcholanthrene results in increased expression of CCND1 mRNA CTD PMID:20713471 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 increases expression ISO Methylcholanthrene results in increased expression of CCNE1 mRNA CTD PMID:29554273 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO Methylcholanthrene results in increased expression of CCNE2 mRNA CTD PMID:20713471 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression		 ISO Methylcholanthrene promotes the reaction [AHR protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CCNG2 mRNA] CTD PMID:20348232 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Cd300e Cd300e molecule increases expression ISO Methylcholanthrene results in increased expression of CD300E mRNA CTD PMID:25926378 NCBI chr10:100,289,729...100,309,996
Ensembl chr10:100,291,437...100,299,311 		JBrowse link
G Cd300lb CD300 molecule-like family member b increases expression ISO Methylcholanthrene results in increased expression of CD300LB mRNA CTD PMID:20713471 NCBI chr10:99,964,801...99,974,790
Ensembl chr10:99,964,801...99,974,790 		JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex decreases expression ISO Methylcholanthrene results in decreased expression of CD3D mRNA CTD PMID:25926378 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
increases expression		 ISO [Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of CD44 mRNA alternative form
Methylcholanthrene results in increased expression of CD44 mRNA		 CTD PMID:15390079 PMID:20713471 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd48 Cd48 molecule increases expression ISO Methylcholanthrene results in increased expression of CD48 mRNA CTD PMID:20713471 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142 		JBrowse link
G Cd5 Cd5 molecule increases expression ISO Methylcholanthrene results in increased expression of CD5 mRNA CTD PMID:25926378 NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CD55 promoter] CTD PMID:20348232 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd59b CD59b molecule increases mutagenesis ISO Methylcholanthrene results in increased mutagenesis of CD59 protein CTD PMID:17045307 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cd9 CD9 molecule multiple interactions
decreases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of CD9 mRNA] CTD PMID:29094188 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cd96 CD96 molecule multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CD96 mRNA CTD PMID:25926378 NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621 		JBrowse link
G Cda cytidine deaminase increases expression ISO Methylcholanthrene results in increased expression of CDA mRNA CTD PMID:20713471 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Methylcholanthrene results in increased expression of CDC20 mRNA CTD PMID:20713471 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc25c cell division cycle 25C increases expression ISO Methylcholanthrene results in increased expression of CDC25C mRNA CTD PMID:20713471 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO Methylcholanthrene results in increased expression of CDC45 mRNA CTD PMID:20713471 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Methylcholanthrene results in increased expression of CDC6 mRNA CTD PMID:20713471 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO Methylcholanthrene results in increased expression of CDCA2 mRNA CTD PMID:20713471 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO Methylcholanthrene results in increased expression of CDCA3 mRNA CTD PMID:20713471 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO Methylcholanthrene results in increased expression of CDCA5 mRNA CTD PMID:20713471 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO Methylcholanthrene results in increased expression of CDCA8 mRNA CTD PMID:20713471 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Methylcholanthrene results in decreased expression of CDH1 protein CTD PMID:16619036 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh13 cadherin 13 decreases expression ISO Methylcholanthrene results in decreased expression of CDH13 mRNA CTD PMID:20713471 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CDH2 gene CTD PMID:21163286 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdh5 cadherin 5 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CDH5 mRNA CTD PMID:25926378 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
decreases methylation
increases expression
increases acetylation		 ISO
EXP		 Methylcholanthrene results in decreased expression of CDK2 protein
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased methylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CDK2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]		 CTD PMID:18022818 PMID:29094188 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
increases response to substance
multiple interactions		 ISO Methylcholanthrene results in increased expression of CDKN1A mRNA
Methylcholanthrene results in increased expression of CDKN1A protein
CDKN1A protein results in increased susceptibility to Methylcholanthrene
Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]; resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]
SB 203580 inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A mRNA]		 CTD PMID:15882963 PMID:18022818 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases response to substance
increases expression		 ISO Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]
CDKN1B protein results in increased susceptibility to Methylcholanthrene		 CTD PMID:18022818 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2aipnl CDKN2A interacting protein N-terminal like increases expression ISO Methylcholanthrene results in increased expression of CDKN2AIPNL mRNA CTD PMID:20713471 NCBI chr10:36,231,134...36,240,569
Ensembl chr10:36,231,087...36,240,564 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Methylcholanthrene results in increased expression of CDKN3 mRNA CTD PMID:20713471 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 increases expression ISO Methylcholanthrene results in increased expression of CDT1 mRNA CTD PMID:20713471 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Ceacam19 CEA cell adhesion molecule 19 increases expression ISO Methylcholanthrene results in increased expression of CEACAM19 mRNA CTD PMID:25926378 NCBI chr 1:79,542,107...79,550,927
Ensembl chr 1:79,542,107...79,550,927 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA CTD PMID:23519560 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein] CTD PMID:21250977 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cenpa centromere protein A increases expression ISO Methylcholanthrene results in increased expression of CENPA mRNA CTD PMID:20713471 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpe centromere protein E increases expression ISO Methylcholanthrene results in increased expression of CENPE mRNA CTD PMID:20713471 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cenpf centromere protein F increases expression ISO Methylcholanthrene results in increased expression of CENPF mRNA CTD PMID:20713471 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cenph centromere protein H increases expression ISO Methylcholanthrene results in increased expression of CENPH mRNA CTD PMID:20713471 NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154 		JBrowse link
G Cenpi centromere protein I increases expression ISO Methylcholanthrene results in increased expression of CENPI mRNA CTD PMID:20713471 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657 		JBrowse link
G Cenpk centromere protein K increases expression ISO Methylcholanthrene results in increased expression of CENPK mRNA CTD PMID:20713471 NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706 		JBrowse link
G Cenpl centromere protein L multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CENPL promoter] CTD PMID:20348232 NCBI chr13:73,337,235...73,352,115
Ensembl chr13:73,337,257...73,352,114 		JBrowse link
G Cenpu centromere protein U increases expression ISO Methylcholanthrene results in increased expression of CENPU mRNA CTD PMID:20713471 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cep55 centrosomal protein 55 increases expression ISO Methylcholanthrene results in increased expression of CEP55 mRNA CTD PMID:20713471 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394 		JBrowse link
G Cep70 centrosomal protein 70 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CEP70 promoter] CTD PMID:20348232 NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855 		JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO Methylcholanthrene results in decreased expression of CES1 protein CTD PMID:10640517 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H decreases expression ISO Methylcholanthrene results in decreased expression of CES2 protein CTD PMID:10640517 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Ces3a carboxylesterase 3a increases expression ISO Methylcholanthrene results in increased expression of CES3 mRNA CTD PMID:20713471 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cfap61 cilia and flagella associated protein 61 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CFAP61 promoter] CTD PMID:20348232 NCBI chr 3:133,354,400...133,633,310
Ensembl chr 3:133,354,197...133,633,320 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO Methylcholanthrene results in increased expression of CHD1L mRNA CTD PMID:25926378 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 increases expression ISO Methylcholanthrene results in increased expression of CHD8 mRNA CTD PMID:25926378 NCBI chr15:24,905,789...24,965,461
Ensembl chr15:24,905,789...24,951,285 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CHFR mRNA CTD PMID:25926378 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Methylcholanthrene results in increased expression of CHI3L1 mRNA CTD PMID:20713471 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chic1 cysteine-rich hydrophobic domain 1 increases expression ISO Methylcholanthrene results in increased expression of CHIC1 mRNA CTD PMID:20713471 NCBI chr  X:68,362,014...68,406,155
Ensembl chr  X:68,361,969...68,437,887 		JBrowse link
G Chic2 cysteine-rich hydrophobic domain 2 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CHIC2 mRNA CTD PMID:25926378 NCBI chr14:33,157,669...33,192,015
Ensembl chr14:33,157,537...33,191,895 		JBrowse link
G Chka choline kinase alpha increases expression EXP Methylcholanthrene results in increased expression of CHKA mRNA CTD PMID:7852267 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chpt1 choline phosphotransferase 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CHPT1 promoter] CTD PMID:20348232 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103 		JBrowse link
G Chrdl2 chordin-like 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CHRDL2 promoter] CTD PMID:20348232 NCBI chr 1:154,343,201...154,370,651
Ensembl chr 1:154,343,201...154,370,640 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA CTD PMID:23519560 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Cilk1 ciliogenesis associated kinase 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CILK1 promoter] CTD PMID:20348232 NCBI chr 8:78,984,075...79,042,695
Ensembl chr 8:78,984,258...79,042,691 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CISD1 promoter] CTD PMID:20348232 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO Methylcholanthrene results in decreased expression of CISH mRNA CTD PMID:22978700 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO Methylcholanthrene results in increased expression of CKAP2 mRNA CTD PMID:20713471 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Ckap2l cytoskeleton associated protein 2-like increases expression ISO Methylcholanthrene results in increased expression of CKAP2L mRNA CTD PMID:20713471 NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Methylcholanthrene results in increased expression of CKS2 mRNA CTD PMID:20713471 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn17 claudin 17 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CLDN17 promoter] CTD PMID:20348232 NCBI chr11:27,827,454...27,828,630
Ensembl chr11:27,827,454...27,828,630 		JBrowse link
G Clk3 CDC-like kinase 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CLK3 promoter] CTD PMID:20348232 NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181 		JBrowse link
G Clpsl2 colipase-like 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CLPSL2 promoter] CTD PMID:20348232 NCBI chr20:6,608,128...6,610,951
Ensembl chr20:6,608,128...6,610,951 		JBrowse link
G Clspn claspin increases expression ISO Methylcholanthrene results in increased expression of CLSPN mRNA CTD PMID:20713471 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Cmip c-Maf-inducing protein multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CMIP mRNA CTD PMID:25926378 NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709 		JBrowse link
G Cnst consortin, connexin sorting protein increases expression ISO Methylcholanthrene results in increased expression of CNST mRNA CTD PMID:23397585 NCBI chr13:91,296,740...91,373,531
Ensembl chr13:91,296,142...91,373,531 		JBrowse link
G Cntn1 contactin 1 increases expression ISO Methylcholanthrene results in increased expression of CNTN1 mRNA CTD PMID:20713471 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL11A1 mRNA CTD PMID:20713471 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL3A1 mRNA CTD PMID:20713471 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL5A1 mRNA CTD PMID:20713471 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL5A2 mRNA CTD PMID:20713471 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL8A1 mRNA CTD PMID:20713471 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO Methylcholanthrene results in decreased expression of COTL1 mRNA CTD PMID:20713471 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions
increases expression		 ISO
EXP		 Methylcholanthrene promotes the reaction [AHR protein binds to COX4I1 promoter]
Methylcholanthrene results in increased expression of COX4I1 mRNA		 CTD PMID:20348232 PMID:23273579 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921 		JBrowse link
G Cpox coproporphyrinogen oxidase increases expression ISO Methylcholanthrene results in increased expression of CPOX mRNA CTD PMID:20713471 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Methylcholanthrene results in increased expression of CPT1A protein CTD PMID:25786523 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP Methylcholanthrene results in increased expression of CREB1 mRNA CTD PMID:23273579 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO Methylcholanthrene results in decreased expression of CREM mRNA CTD PMID:35487396 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CRKL promoter] CTD PMID:20348232 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Cryz crystallin zeta multiple interactions
increases expression
increases activity		 ISO AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Lead promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA] CTD PMID:15297030 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Csmd3 CUB and Sushi multiple domains 3 decreases expression ISO Methylcholanthrene results in decreased expression of CSMD3 mRNA CTD PMID:20713471 NCBI chr 7:78,747,322...80,066,466
Ensembl chr 7:78,748,480...80,066,369 		JBrowse link
G Csn2 casein beta multiple interactions EXP Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of CSN2 mRNA] CTD PMID:26372666 NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO Methylcholanthrene results in increased expression of CSRP2 mRNA CTD PMID:20713471 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Ctnna1 catenin alpha 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CTNNA1 promoter] CTD PMID:20348232 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Ctnnb1 catenin beta 1 affects response to substance
increases response to substance
multiple interactions		 ISO CTNNB1 protein affects the susceptibility to Methylcholanthrene
CTNNB1 protein results in increased susceptibility to Methylcholanthrene
CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]		 CTD PMID:21498875 PMID:25174530 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsd cathepsin D increases expression ISO Methylcholanthrene results in increased expression of CTSD mRNA CTD PMID:16257430 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CUEDC1 promoter] CTD PMID:20348232 NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Methylcholanthrene results in increased expression of CX3CL1 mRNA CTD PMID:20713471 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA CTD PMID:23519560 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA CTD PMID:23519560 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL5 mRNA CTD PMID:23519560 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cyb5b cytochrome b5 type B multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CYB5B promoter] CTD PMID:20348232 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO Methylcholanthrene results in decreased expression of CYP11A1 mRNA CTD PMID:35487396 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression ISO Methylcholanthrene affects the expression of CYP17A1 mRNA CTD PMID:35487396 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
decreases response to substance
increases acetylation
increases methylation
increases activity
increases metabolic processing
decreases activity		 ISO
EXP		 [Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A1 mRNA; [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; [Methylcholanthrene co-treated with Oxygen deficiency] results in increased expression of CYP1A1 mRNA; [Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [NR3C1 protein co-treated with Dexamethasone] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [pirinixic acid co-treated with Methylcholanthrene] results in increased activity of CYP1A1 protein; [pirinixic acid co-treated with Methylcholanthrene] results in increased expression of CYP1A1 mRNA; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Glyburide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [Nicardipine results in increased activity of and results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [pirinixic acid results in increased activity of CYP1A1 protein]; Methylcholanthrene promotes the reaction [pirinixic acid results in increased expression of CYP1A1 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Oxygen deficiency affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; tyrphostin AG 1024 inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; tyrphostin AG 1024 inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]
3-methylcholanthrene increases expression of mRNA, protein in rat heart
CYP1A1 gene mutant form results in decreased susceptibility to Methylcholanthrene
Methylcholanthrene results in increased acetylation of CYP1A1 promoter
Methylcholanthrene results in increased methylation of CYP1A1 promoter
Methylcholanthrene results in increased expression of CYP1A1 mRNA; Methylcholanthrene results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; [Methylcholanthrene binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [Methylcholanthrene binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; AHR affects the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; AHR affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene affects the expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Arsenic inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Cadmium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Chromium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CYP1A1 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A2 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]; Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; POR gene mutant form inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]
[[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; [Methylcholanthrene co-treated with GNMT protein] results in increased expression of CYP1A1 mRNA; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CYP1A1 promoter]; Buthionine Sulfoximine inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Ethoxyquin inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; isoimperatorin promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [CYP1A1 protein results in increased oxidation of Toluene]; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A1 protein]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased metabolism of Methylcholanthrene
Methylcholanthrene results in increased activity of CYP1A1 promoter; Methylcholanthrene results in increased activity of CYP1A1 protein
Methylcholanthrene results in decreased activity of CYP1A1 protein		 CTD
RGD		 PMID:1316759 PMID:1617633 PMID:1994898 PMID:2154949 PMID:3785172 More... RGD:401794453 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases response to substance
increases expression
increases activity
affects response to substance		 ISO
EXP		 [Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A2 mRNA; [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Dehydroepiandrosterone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Oxygen deficiency inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]
CYP1A2 gene mutant form results in increased susceptibility to Methylcholanthrene
Methylcholanthrene results in increased expression of CYP1A2 mRNA; Methylcholanthrene results in increased expression of CYP1A2 protein
[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A1 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A2 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]
[[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; [Methylcholanthrene results in increased activity of CYP1A2 protein] which results in increased oxidation of Uroporphyrinogens; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene promotes the reaction [CYP1A2 protein results in increased oxidation of Toluene]; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A2 protein; protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]
CYP1A2 affects the susceptibility to Methylcholanthrene		 CTD PMID:1617633 PMID:1994898 PMID:3785172 PMID:4054433 PMID:6749129 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
increases metabolic processing
increases chemical synthesis		 ISO
EXP		 Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1B1 protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
3-methylcholanthrene increases expression of mRNA, protein in rat heart
Methylcholanthrene results in increased expression of CYP1B1 mRNA; Methylcholanthrene results in increased expression of CYP1B1 protein
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
CYP1B1 protein results in increased metabolism of Methylcholanthrene
CYP1B1 protein results in increased chemical synthesis of Methylcholanthrene metabolite		 CTD
RGD		 PMID:9783729 PMID:10402558 PMID:11323195 PMID:11328961 PMID:11502733 More... RGD:401794453 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO Methylcholanthrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:19244278 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP2A1 mRNA CTD PMID:11323195 PMID:19118567 PMID:22934830 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression
increases expression		 EXP Methylcholanthrene results in decreased expression of CYP2A2 mRNA
Methylcholanthrene results in increased expression of CYP2A2 mRNA		 CTD PMID:11328961 PMID:22934830 PMID:23273579 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions
increases expression		 ISO
EXP		 Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter]
Methylcholanthrene results in increased expression of CYP2A4 mRNA
Methylcholanthrene results in increased expression of CYP2A3 mRNA		 CTD PMID:12845369 PMID:20348232 PMID:22934830 PMID:30503582 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression
affects expression		 EXP
ISO		 Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B1 protein]
Methylcholanthrene results in decreased expression of CYP2B10 mRNA
Methylcholanthrene affects the expression of CYP2B1 mRNA		 CTD PMID:18486174 PMID:23273579 PMID:30503582 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions
affects expression		 EXP Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B2 protein]
Methylcholanthrene affects the expression of CYP2B2 mRNA		 CTD PMID:18486174 PMID:23273579 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
increases expression		 EXP
ISO		 Methylcholanthrene results in decreased expression of CYP2B3 mRNA
Methylcholanthrene results in increased expression of CYP2B9 mRNA		 CTD PMID:11328961 PMID:30503582 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
increases expression
decreases expression		 EXP Methylcholanthrene promotes the reaction [CYP2C11 protein results in increased oxidation of Toluene]
Methylcholanthrene results in increased expression of CYP2C11 mRNA
Methylcholanthrene results in decreased expression of CYP2C11 mRNA		 CTD PMID:1994898 PMID:10476907 PMID:22978700 PMID:23273579 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 increases expression EXP Methylcholanthrene results in increased expression of CYP2C13 protein CTD PMID:25786523 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO Methylcholanthrene results in increased expression of CYP2C29 mRNA CTD PMID:30503582
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression EXP Methylcholanthrene results in increased expression of CYP2D4 mRNA CTD PMID:11328961 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
decreases expression
decreases activity		 EXP
ISO		 [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; [Methylcholanthrene results in decreased expression of CYP2E1 protein] which affects the metabolism of Benzene; [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; Methylcholanthrene promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene]
3-methylcholanthrene increases expression of mRNA, protein in rat heart
Methylcholanthrene results in decreased expression of CYP2E1 mRNA
Methylcholanthrene results in increased expression of CYP2E1 mRNA; Methylcholanthrene results in increased expression of CYP2E1 protein
Methylcholanthrene results in decreased expression of CYP2E1 mRNA; Methylcholanthrene results in decreased expression of CYP2E1 protein
Methylcholanthrene results in decreased activity of CYP2E1 protein		 CTD
RGD		 PMID:1994898 PMID:3113478 PMID:7493548 PMID:8734847 PMID:9118891 More... RGD:401794453 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP2S1 mRNA CTD PMID:19883719 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Dactinomycin inhibits the reaction [Methylcholanthrene results in increased expression of CYP3A2 mRNA]
[Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP3A4 mRNA; Methylcholanthrene results in decreased expression of and results in decreased activity of CYP3A4 protein
Methylcholanthrene results in decreased expression of CYP3A4 protein		 CTD PMID:10640517 PMID:11181506 PMID:23846873 PMID:24999631 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP3A23-3A1 mRNA CTD PMID:23273579 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of CYP3A5 mRNA
AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP3A5 mRNA]		 CTD PMID:33408298 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression
increases expression 		EXP Methylcholanthrene results in increased expression of CYP4A3 mRNA
3-methylcholanthrene increases expression of mRNA in rat heart		 CTD
RGD		 PMID:19889059 PMID:19889059 RGD:401794453 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP4B1 mRNA CTD PMID:23273579 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression
increases expression 		EXP Methylcholanthrene results in increased expression of CYP4F4 mRNA
3-methylcholanthrene increases expression of mRNA in rat heart		 CTD
RGD		 PMID:19889059 PMID:19889059 RGD:401794453 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506 		JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression
increases expression 		EXP Methylcholanthrene results in increased expression of CYP4F5 mRNA
3-methylcholanthrene increases expression of mRNA in rat heart		 CTD
RGD		 PMID:19889059 PMID:19889059 RGD:401794453 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression EXP Methylcholanthrene results in decreased expression of CYP4F6 mRNA CTD PMID:11328961 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Dab2 DAB adaptor protein 2 increases expression ISO Methylcholanthrene results in increased expression of DAB2 mRNA CTD PMID:20713471 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO Methylcholanthrene results in decreased expression of DACT1 mRNA CTD PMID:20713471 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906 		JBrowse link
G Dapk1 death associated protein kinase 1 multiple interactions EXP
ISO		 [Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of DAPK1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of DAPK1 promoter
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA		 CTD PMID:20970405 PMID:23519560 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dapk2 death-associated protein kinase 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA CTD PMID:23519560 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Dazl deleted in azoospermia-like decreases expression ISO Methylcholanthrene results in decreased expression of DAZL mRNA CTD PMID:35487396 NCBI chr 9:10,695,593...10,712,330
Ensembl chr 9:10,695,592...10,712,323 		JBrowse link
G Dbn1 drebrin 1 decreases expression ISO Methylcholanthrene results in decreased expression of DBN1 mRNA CTD PMID:20713471 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dck deoxycytidine kinase increases expression ISO Methylcholanthrene results in increased expression of DCK mRNA CTD PMID:20713471 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Dclk1 doublecortin-like kinase 1 decreases expression ISO Methylcholanthrene results in decreased expression of DCLK1 mRNA CTD PMID:20713471 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDR2 mRNA] CTD PMID:29094188 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO Methylcholanthrene results in increased expression of DDX17 mRNA CTD PMID:25926378 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO Methylcholanthrene results in decreased expression of DDX4 mRNA CTD PMID:35487396 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDX5 mRNA] CTD PMID:29094188 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DEGS1 promoter] CTD PMID:20348232 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Depdc1 DEP domain containing 1 increases expression ISO Methylcholanthrene results in increased expression of DEPDC1A mRNA CTD PMID:20713471 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951 		JBrowse link
G Depdc1b DEP domain containing 1B increases expression ISO Methylcholanthrene results in increased expression of DEPDC1B mRNA CTD PMID:20713471 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO Methylcholanthrene results in decreased expression of DEPTOR mRNA CTD PMID:20713471 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dhfr dihydrofolate reductase increases expression ISO Methylcholanthrene results in increased expression of DHFR mRNA CTD PMID:20713471 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Diaph1 diaphanous-related formin 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DIAPH1 promoter] CTD PMID:20348232 NCBI chr18:29,669,659...29,769,070
Ensembl chr18:29,669,659...29,769,172 		JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO Methylcholanthrene results in increased expression of DLGAP5 mRNA CTD PMID:20713471 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 increases expression
multiple interactions		 EXP Methylcholanthrene results in increased expression of DLL1 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DLL1 mRNA]		 CTD PMID:29094188 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO Methylcholanthrene results in increased expression of DMP1 mRNA CTD PMID:20713471 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions
increases acetylation
increases methylation
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of DNAJB6 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DNAJB6 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of DNAJB6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter] CTD PMID:29094188 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659 		JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 increases expression ISO Methylcholanthrene results in increased expression of DNAJC9 mRNA CTD PMID:20713471 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein CTD PMID:21163286 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT3A protein CTD PMID:21163286 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases expression ISO Methylcholanthrene results in increased expression of DTL mRNA CTD PMID:20713471 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dtna dystrobrevin, alpha multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DTNA promoter] CTD PMID:20348232 NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261 		JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DUSP14 promoter] CTD PMID:20348232 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329 		JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Methylcholanthrene results in increased expression of DUSP4 mRNA CTD PMID:20713471 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Methylcholanthrene results in increased expression of DUSP6 mRNA CTD PMID:20713471 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dut deoxyuridine triphosphatase increases expression ISO Methylcholanthrene results in increased expression of DUT mRNA CTD PMID:20713471 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 decreases expression ISO Methylcholanthrene results in decreased expression of DYRK2 mRNA CTD PMID:20713471 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106 		JBrowse link
G E2f7 E2F transcription factor 7 increases expression ISO Methylcholanthrene results in increased expression of E2F7 mRNA CTD PMID:20713471 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 increases expression ISO Methylcholanthrene results in increased expression of E2F8 mRNA CTD PMID:20713471 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression ISO Methylcholanthrene results in increased expression of ECM1 mRNA CTD PMID:20713471 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Ect2 epithelial cell transforming 2 increases expression ISO Methylcholanthrene results in increased expression of ECT2 mRNA CTD PMID:20713471 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Efna5 ephrin A5 decreases expression ISO Methylcholanthrene results in decreased expression of EFNA5 mRNA CTD PMID:20713471 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413 		JBrowse link
G Efnb1 ephrin B1 increases expression ISO Methylcholanthrene results in increased expression of EFNB1 mRNA CTD PMID:20713471 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP Methylcholanthrene results in decreased expression of EGFR mRNA CTD PMID:29094188 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr2 early growth response 2 increases expression ISO Methylcholanthrene results in increased expression of EGR2 mRNA CTD PMID:29554273 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr3 early growth response 3 increases expression ISO Methylcholanthrene results in increased expression of EGR3 mRNA CTD PMID:20713471 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehd3 EH-domain containing 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to EHD3 promoter] CTD PMID:20348232 NCBI chr 6:21,640,861...21,665,601
Ensembl chr 6:21,639,290...21,665,236 		JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked increases expression ISO Methylcholanthrene results in increased expression of EIF1AY mRNA CTD PMID:20713471 NCBI chr  X:35,498,698...35,513,402
Ensembl chr  X:35,498,517...35,513,335 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta increases expression ISO Methylcholanthrene results in increased expression of EIF2B2 mRNA CTD PMID:20713471 NCBI chr 6:104,866,926...104,873,351
Ensembl chr 6:104,866,753...104,873,353 		JBrowse link
G Eif4e1b eukaryotic translation initiation factor 4E family member 1B multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA CTD PMID:23519560 NCBI chr17:9,831,338...9,856,250
Ensembl chr17:9,832,230...9,835,137 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Methylcholanthrene results in increased expression of EIF4EBP2 mRNA CTD PMID:25926378 NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA CTD PMID:23519560 NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 increases expression ISO Methylcholanthrene results in increased expression of ELOVL3 mRNA CTD PMID:25926378 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 increases expression ISO Methylcholanthrene results in increased expression of EME1 mRNA CTD PMID:20713471 NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Methylcholanthrene results in increased expression of EMP1 mRNA CTD PMID:20713471 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904 		JBrowse link
G Enpep glutamyl aminopeptidase decreases expression ISO Methylcholanthrene results in decreased expression of ENPEP mRNA CTD PMID:20713471 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Methylcholanthrene results in decreased expression of ENPP2 mRNA CTD PMID:20713471 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ephb6 Eph receptor B6 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA CTD PMID:23519560 NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity
increases expression		 ISO
EXP		 Methylcholanthrene results in increased activity of EPHX1 protein
Methylcholanthrene results in increased expression of EPHX1 mRNA		 CTD PMID:3621371 PMID:23273579 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity
increases expression
decreases activity		 EXP
ISO		 Methylcholanthrene results in increased activity of EPHX2 protein
3-methylcholanthrene increases expression of mRNA, protein in rat heart
Methylcholanthrene results in decreased activity of EPHX2 protein
Methylcholanthrene results in increased expression of EPHX2 mRNA; Methylcholanthrene results in increased expression of EPHX2 protein		 CTD
RGD		 PMID:3621371 PMID:19889059 PMID:19889059 RGD:401794453 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to EPS15 promoter] CTD PMID:20348232 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221 		JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO Methylcholanthrene results in increased expression of EPS8 mRNA CTD PMID:20713471 NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter] CTD PMID:20348232 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase increases expression ISO Methylcholanthrene results in increased expression of ERCC6L mRNA CTD PMID:20713471 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756 		JBrowse link
G Ereg epiregulin increases expression ISO Methylcholanthrene results in increased expression of EREG mRNA CTD PMID:20713471 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO Methylcholanthrene results in increased expression of ESCO2 mRNA CTD PMID:20713471 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase increases expression ISO Methylcholanthrene results in increased expression of ESPL1 mRNA CTD PMID:20713471 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
increases expression
increases activity
affects binding		 ISO
EXP		 Fulvestrant inhibits the reaction [Methylcholanthrene results in increased expression of ESR1 mRNA]; Methylcholanthrene binds to and results in increased activity of ESR1 protein; Methylcholanthrene promotes the reaction [AHR protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ESR1 protein binds to CYP1A1 promoter]
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA]
Methylcholanthrene results in increased activity of ESR1 protein
Methylcholanthrene binds to ESR1 protein		 CTD PMID:16257430 PMID:16489053 PMID:16972788 PMID:20348232 PMID:23273579 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Etv1 ETS variant transcription factor 1 increases expression ISO Methylcholanthrene results in increased expression of ETV1 mRNA CTD PMID:20713471 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775 		JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression ISO Methylcholanthrene results in increased expression of ETV5 mRNA CTD PMID:20713471 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215 		JBrowse link
G Exo1 exonuclease 1 increases expression ISO Methylcholanthrene results in increased expression of EXO1 mRNA CTD PMID:20713471 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exosc9 exosome component 9 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to EXOSC9 promoter] CTD PMID:20348232 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051 		JBrowse link
G F11r F11 receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA CTD PMID:23519560 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression
multiple interactions		 ISO Methylcholanthrene results in decreased expression of FABP4 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of FABP4 mRNA		 CTD PMID:25926378 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA CTD PMID:23519560 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fcar Fc alpha receptor increases expression ISO Methylcholanthrene results in increased expression of FCAR mRNA CTD PMID:21911031 NCBI chr 1:69,626,458...69,660,558 JBrowse link
G Fchsd2 FCH and double SH3 domains 2 increases expression ISO Methylcholanthrene results in increased expression of FCHSD2 mRNA CTD PMID:20713471 NCBI chr 1:155,444,471...155,685,350
Ensembl chr 1:155,444,460...155,685,539 		JBrowse link
G Fcrl5 Fc receptor-like 5 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of FCRL5 mRNA CTD PMID:25926378 NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Methylcholanthrene results in decreased expression of FDPS mRNA CTD PMID:20713471 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fdxr ferredoxin reductase increases expression ISO Methylcholanthrene results in increased expression of FDXR mRNA CTD PMID:22100608 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA CTD PMID:23519560 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf10 fibroblast growth factor 10 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA CTD PMID:23519560 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf18 fibroblast growth factor 18 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA CTD PMID:23519560 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA CTD PMID:23519560 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Methylcholanthrene results in increased expression of FGFR1 mRNA CTD PMID:20713471 PMID:29554273 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA CTD PMID:23519560 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase multiple interactions
decreases expression		 EXP
ISO		 [Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of FHIT protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of FHIT promoter
Methylcholanthrene results in decreased expression of FHIT mRNA		 CTD PMID:20970405 PMID:22100608 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Fignl1 fidgetin-like 1 increases expression ISO Methylcholanthrene results in increased expression of FIGNL1 mRNA CTD PMID:20713471 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Methylcholanthrene results in increased expression of FMO2 mRNA CTD PMID:20570689 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 multiple interactions
decreases expression
increases expression		 ISO
EXP		 AHR protein affects the reaction [Methylcholanthrene results in increased expression of FMO3 mRNA]; Methylcholanthrene promotes the reaction [TRP53 protein binds to FMO3 5' UTR]
Methylcholanthrene results in decreased expression of FMO3 mRNA		 CTD PMID:20570689 PMID:23273579 PMID:23846873 PMID:25926378 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fmod fibromodulin decreases expression ISO Methylcholanthrene results in decreased expression of FMOD mRNA CTD PMID:20713471 NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Methylcholanthrene results in increased expression of FOSL1 mRNA CTD PMID:20713471 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxm1 forkhead box M1 affects response to substance ISO FOXM1 protein affects the susceptibility to Methylcholanthrene CTD PMID:18345025 PMID:19672312 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxn1 forkhead box N1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to FOXN1 promoter] CTD PMID:20348232 NCBI chr10:63,251,400...63,273,710
Ensembl chr10:63,251,400...63,273,710 		JBrowse link
G Foxn3 forkhead box N3 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of FOXN3 mRNA] CTD PMID:29094188 NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401 		JBrowse link
G Foxn4 forkhead box N4 multiple interactions
increases expression		 ISO Methylcholanthrene promotes the reaction [AHR protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of FOXN4 mRNA] CTD PMID:20348232 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of FOXO3 mRNA CTD PMID:29094188 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to FREM2 promoter] CTD PMID:20348232 NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785 		JBrowse link
G Fryl FRY like transcription coactivator increases expression ISO Methylcholanthrene results in increased expression of FRYL mRNA CTD PMID:20713471 NCBI chr14:34,956,623...35,189,738
Ensembl chr14:34,956,620...35,190,222 		JBrowse link
G Fst follistatin decreases expression ISO Methylcholanthrene results in decreased expression of FST mRNA CTD PMID:20713471 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Fstl1 follistatin-like 1 decreases expression ISO Methylcholanthrene results in decreased expression of FSTL1 mRNA CTD PMID:20713471 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO Methylcholanthrene results in increased expression of FUT8 mRNA CTD PMID:20713471 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677 		JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression ISO Methylcholanthrene results in increased expression of FXYD5 mRNA CTD PMID:20713471 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA CTD PMID:23519560 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gab2 GRB2-associated binding protein 2 decreases expression ISO Methylcholanthrene results in decreased expression of GAB2 mRNA CTD PMID:20713471 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA CTD PMID:23519560 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Methylcholanthrene results in decreased expression of GADD45A mRNA CTD PMID:20713471 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 increases expression ISO Methylcholanthrene results in increased expression of GALNT15 mRNA CTD PMID:20713471 NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014 		JBrowse link
G Galnt18 polypeptide N-acetylgalactosaminyltransferase 18 decreases expression ISO Methylcholanthrene results in decreased expression of GALNT18 mRNA CTD PMID:20713471 NCBI chr 1:165,593,180...165,904,268
Ensembl chr 1:165,593,187...165,904,268 		JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression ISO Methylcholanthrene results in increased expression of GALNT7 mRNA CTD PMID:20713471 NCBI chr16:32,578,643...32,703,189
Ensembl chr16:32,578,690...32,702,690 		JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 increases expression ISO Methylcholanthrene results in increased expression of GAS2L3 mRNA CTD PMID:20713471 NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411 		JBrowse link
G Gata6 GATA binding protein 6 multiple interactions
increases activity		 ISO Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon]
Methylcholanthrene results in increased activity of GATA6 protein		 CTD PMID:16271038 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gcat glycine C-acetyltransferase increases expression ISO Methylcholanthrene results in increased expression of GCAT mRNA CTD PMID:20713471 NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression ISO Methylcholanthrene results in increased expression of GCH1 mRNA CTD PMID:20713471 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator increases expression ISO Methylcholanthrene results in increased expression of GCHFR mRNA CTD PMID:20713471 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080 		JBrowse link
G Gdf9 growth differentiation factor 9 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of GDF9 mRNA CTD PMID:29094188 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression ISO Methylcholanthrene results in decreased expression of GDNF mRNA CTD PMID:35487396 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gdpd4 glycerophosphodiester phosphodiesterase domain containing 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GDPD4 promoter] CTD PMID:20348232 NCBI chr 1:152,233,516...152,342,329
Ensembl chr 1:152,233,499...152,342,158 		JBrowse link
G Gh1 growth hormone 1 decreases activity EXP Methylcholanthrene results in decreased activity of GH1 protein CTD PMID:22978700 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Ghr growth hormone receptor decreases expression
increases expression		 ISO Methylcholanthrene results in decreased expression of GHR mRNA
Methylcholanthrene results in increased expression of GHR protein		 CTD PMID:22978700 PMID:23169610 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Gins3 GINS complex subunit 3 increases expression ISO Methylcholanthrene results in increased expression of GINS3 mRNA CTD PMID:20713471 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 increases expression ISO Methylcholanthrene results in increased expression of GINS4 mRNA CTD PMID:20713471 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Methylcholanthrene results in increased expression of GJA1 mRNA CTD PMID:20713471 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gmnn geminin, DNA replication inhibitor increases expression ISO Methylcholanthrene results in increased expression of GMNN mRNA CTD PMID:20713471 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO Methylcholanthrene results in increased expression of GNB4 mRNA CTD PMID:20713471 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression
multiple interactions		 ISO
EXP		 Methylcholanthrene results in decreased expression of GNMT mRNA
[Methylcholanthrene co-treated with GNMT protein] results in increased expression of CYP1A1 mRNA		 CTD PMID:9261130 PMID:22100608 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Gpc1 glypican 1 increases expression ISO Methylcholanthrene results in increased expression of GPC1 mRNA CTD PMID:20713471 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO Methylcholanthrene results in decreased expression of GPCPD1 mRNA CTD PMID:20713471 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517 		JBrowse link
G Gphb5 glycoprotein hormone subunit beta 5 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GPHB5 promoter] CTD PMID:20348232 NCBI chr 6:94,129,968...94,134,585
Ensembl chr 6:94,131,021...94,133,570 		JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Methylcholanthrene results in increased expression of GPNMB mRNA CTD PMID:20713471 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP
ISO		 Methylcholanthrene results in increased expression of GPX1 mRNA CTD PMID:23273579 PMID:23712962 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GREB1 promoter] CTD PMID:20348232 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA CTD PMID:23519560 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GRIK4 promoter] CTD PMID:20348232 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA CTD PMID:23519560 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Gsdmc gasdermin C multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GSDMC promoter] CTD PMID:20348232 NCBI chr 7:95,594,015...95,606,106
Ensembl chr 7:95,594,015...95,611,344 		JBrowse link
G Gsdmd gasdermin D increases expression ISO Methylcholanthrene results in increased expression of GSDMD mRNA CTD PMID:20713471 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsdme gasdermin E increases expression ISO Methylcholanthrene results in increased expression of GSDME mRNA CTD PMID:20713471 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity
increases expression		 ISO Methylcholanthrene results in increased activity of GSR protein
Methylcholanthrene results in increased expression of GSR mRNA		 CTD PMID:23712962 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gss glutathione synthetase increases activity
increases expression		 ISO Methylcholanthrene results in increased activity of GSS protein
Methylcholanthrene results in increased expression of GSS mRNA		 CTD PMID:23712962 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Methylcholanthrene results in increased expression of GSTA2 mRNA
[Methylcholanthrene co-treated with Copper] results in increased activity of GSTA2 protein; Copper inhibits the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]
Methylcholanthrene results in decreased expression of GSTA2 mRNA		 CTD PMID:10476907 PMID:11328961 PMID:15297030 PMID:23273579 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases expression ISO Methylcholanthrene results in decreased expression of GSTA1 mRNA CTD PMID:23712962 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression EXP Methylcholanthrene results in increased expression of GSTK1 mRNA CTD PMID:23273579 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Methylcholanthrene results in increased expression of GSTM1 mRNA CTD PMID:11328961 PMID:23273579 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Methylcholanthrene results in increased expression of GSTP1 mRNA CTD PMID:19118567 PMID:23273579 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO Methylcholanthrene results in increased expression of GTSE1 mRNA CTD PMID:20713471 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gulp1 GULP PTB domain containing engulfment adaptor 1 increases expression ISO Methylcholanthrene results in increased expression of GULP1 mRNA CTD PMID:23397585 NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005 		JBrowse link
G H2bc1 H2B clustered histone 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to H2BC1 promoter] CTD PMID:20348232 NCBI chr17:41,172,041...41,172,510
Ensembl chr17:41,171,903...41,176,782
Ensembl chr17:41,171,903...41,176,782 		JBrowse link
G H3f3b H3.3 histone B decreases expression ISO Methylcholanthrene results in decreased expression of H3F3B mRNA CTD PMID:20713471 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 increases expression ISO Methylcholanthrene results in increased expression of HACD4 mRNA CTD PMID:20713471 NCBI chr 5:102,887,597...102,915,376
Ensembl chr 5:102,887,588...102,915,338 		JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Methylcholanthrene results in increased expression of HASPIN mRNA CTD PMID:20713471 NCBI chr10:57,747,731...57,750,518
Ensembl chr10:57,747,573...57,750,512 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 increases expression ISO Methylcholanthrene results in increased expression of HBA-A1 mRNA CTD PMID:20713471 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA CTD PMID:23519560 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693 		JBrowse link
G Hcrtr2 hypocretin receptor 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HCRTR2 promoter] CTD PMID:20348232 NCBI chr 8:76,989,834...77,105,953
Ensembl chr 8:76,989,834...77,105,893 		JBrowse link
G Hdac11 histone deacetylase 11 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HDAC11 promoter] CTD PMID:20348232 NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405 		JBrowse link
G Hdac5 histone deacetylase 5 increases expression ISO Methylcholanthrene results in increased expression of HDAC5 mRNA CTD PMID:29554273 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Heph hephaestin increases expression ISO Methylcholanthrene results in increased expression of HEPH mRNA CTD PMID:20713471 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HES1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter] CTD PMID:29094188 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA CTD PMID:23519560 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hhip Hedgehog-interacting protein multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA CTD PMID:23519560 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression EXP Methylcholanthrene results in increased expression of HIF1A mRNA CTD PMID:23273579 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 decreases expression ISO Methylcholanthrene results in decreased expression of HIPK2 mRNA CTD PMID:20713471 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hist1h2bc histone cluster 1, H2bc multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to H2BC21 promoter] CTD PMID:20348232 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Methylcholanthrene results in increased expression of HMGA1 mRNA CTD PMID:20713471 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO Methylcholanthrene results in increased expression of HMGA2 mRNA CTD PMID:20713471 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Methylcholanthrene results in decreased expression of HMGCR mRNA CTD PMID:35487396 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Methylcholanthrene results in decreased expression of HMGCS1 mRNA CTD PMID:20713471 PMID:35487396 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO Methylcholanthrene results in increased expression of HMMR mRNA CTD PMID:20713471 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 [Methylcholanthrene co-treated with Copper] results in increased expression of HMOX1 mRNA; [Methylcholanthrene co-treated with Lead] results in increased expression of HMOX1 mRNA; [Methylcholanthrene co-treated with Mercury] results in increased expression of HMOX1 mRNA
Methylcholanthrene results in increased expression of HMOX1 mRNA		 CTD PMID:15297030 PMID:19889059 PMID:22100608 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions ISO [Butylated Hydroxytoluene co-treated with Methylcholanthrene] affects the localization of HNRNPA1 protein; [Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of HNRNPA1 protein CTD PMID:15390079 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO [Methylcholanthrene co-treated with Butylated Hydroxytoluene] affects the expression of HNRNPA2B1 protein CTD PMID:17477362 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hoxc10 homeo box C10 increases expression ISO Methylcholanthrene results in increased expression of HOXC10 mRNA CTD PMID:20348232 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966 		JBrowse link
G Hoxc11 homeobox C11 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HOXC11 promoter] CTD PMID:20348232 NCBI chr 7:134,091,224...134,094,738
Ensembl chr 7:134,091,552...134,094,738 		JBrowse link
G Hpcal4 hippocalcin-like 4 increases expression ISO Methylcholanthrene results in increased expression of HPCAL4 mRNA CTD PMID:25926378 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO Methylcholanthrene results in increased expression of HPGD mRNA CTD PMID:25926378 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hsbp1 heat shock factor binding protein 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HSBP1 promoter] CTD PMID:20348232 NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821 		JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of HSCB mRNA CTD PMID:25926378 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Methylcholanthrene results in increased expression of HSP90AA1 mRNA CTD PMID:23273579 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA CTD PMID:23519560 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions
increases expression		 EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HSPA8 mRNA] CTD PMID:29094188 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases acetylation
multiple interactions
increases expression		 EXP Methylcholanthrene results in increased acetylation of ICAM1 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of ICAM1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of ICAM1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]		 CTD PMID:29094188 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Methylcholanthrene results in increased expression of ID2 mRNA CTD PMID:20713471 PMID:23397585 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO Methylcholanthrene results in increased expression of ID3 mRNA CTD PMID:23397585 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to IDH2 promoter] CTD PMID:20348232 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Methylcholanthrene results in decreased expression of IDI1 mRNA CTD PMID:20713471 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ier3 immediate early response 3 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of IER3 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to IER3 promoter]		 CTD PMID:20348232 PMID:20713471 PMID:22579512 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Methylcholanthrene results in decreased expression of IFI27 mRNA CTD PMID:20713471 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Methylcholanthrene results in decreased expression of IFI44 mRNA CTD PMID:20713471 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Methylcholanthrene results in increased expression of IFIT2 mRNA CTD PMID:29554273 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Methylcholanthrene results in decreased expression of IFIT3 mRNA CTD PMID:20713471 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO Methylcholanthrene results in increased expression of IFNB1 mRNA CTD PMID:29554273 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Igf2 insulin-like growth factor 2 increases acetylation
multiple interactions
increases expression
increases methylation		 EXP Methylcholanthrene results in increased acetylation of IGF2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of IGF2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IGF2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of IGF2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]		 CTD PMID:29094188 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO Methylcholanthrene results in increased expression of IGFBP6 mRNA CTD PMID:20713471 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Igfbpl1 insulin-like growth factor binding protein-like 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to IGFBPL1 promoter] CTD PMID:20348232 NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833 		JBrowse link
G Il12a interleukin 12A increases expression ISO Methylcholanthrene results in increased expression of IL12A mRNA CTD PMID:14993811 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 increases expression ISO Methylcholanthrene results in increased expression of IL12RB1 mRNA CTD PMID:20713471 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il18 interleukin 18 increases expression ISO Methylcholanthrene results in increased expression of IL18 mRNA CTD PMID:14993811 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18r1 interleukin 18 receptor 1 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL18R1 mRNA CTD PMID:25926378 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein increases expression ISO Methylcholanthrene results in increased expression of IL18RAP mRNA CTD PMID:20713471 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Methylcholanthrene results in increased expression of IL1A mRNA CTD PMID:14993811 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of IL1B mRNA
[Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of IL1B mRNA; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]		 CTD PMID:14993811 PMID:35487396 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Methylcholanthrene results in increased expression of IL1RL1 mRNA CTD PMID:20713471 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of IL6 mRNA
[Methylcholanthrene co-treated with TNF protein] results in increased expression of IL6 mRNA		 CTD PMID:14993811 PMID:23396138 PMID:29554273 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL6ST mRNA CTD PMID:25926378 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Il7r interleukin 7 receptor multiple interactions
increases expression		 ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL7R mRNA
Methylcholanthrene results in increased expression of IL7R mRNA		 CTD PMID:25926378 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 decreases expression ISO Methylcholanthrene results in decreased expression of IMMP2L mRNA CTD PMID:20713471 NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840 		JBrowse link
G Inhbc inhibin subunit beta C multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to INHBC promoter] CTD PMID:20348232 NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO Methylcholanthrene promotes the reaction [Glucose results in increased secretion of INS protein alternative form] CTD PMID:31776611 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 increases expression ISO Methylcholanthrene results in increased expression of IQGAP3 mRNA CTD PMID:20713471 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956 		JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to IRF2BPL promoter] CTD PMID:20348232 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401 		JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO Methylcholanthrene results in decreased expression of IRS1 mRNA CTD PMID:29554273 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Isoc2b isochorismatase domain containing 2b multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ISOC2 promoter] CTD PMID:20348232 NCBI chr 1:68,972,960...68,993,760
Ensembl chr 1:68,972,960...68,993,757 		JBrowse link
G Itga10 integrin subunit alpha 10 increases expression ISO Methylcholanthrene results in increased expression of ITGA10 mRNA CTD PMID:20713471 NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172 		JBrowse link
G Itga7 integrin subunit alpha 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA CTD PMID:23519560 NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450 		JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Methylcholanthrene results in decreased expression of ITGB5 mRNA CTD PMID:23397585 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472 		JBrowse link
G Itgb8 integrin subunit beta 8 decreases expression
multiple interactions		 EXP Methylcholanthrene results in decreased expression of ITGB8 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ITGB8 mRNA]		 CTD PMID:29094188 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Itgbl1 integrin subunit beta like 1 increases expression ISO Methylcholanthrene results in increased expression of ITGBL1 mRNA CTD PMID:20713471 NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions
increases expression		 ISO Methylcholanthrene promotes the reaction [AHR protein binds to ITPR1 promoter]
Methylcholanthrene results in increased expression of ITPR1 mRNA		 CTD PMID:20348232 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression
increases expression
multiple interactions
increases acetylation
increases methylation		 ISO
EXP		 Methylcholanthrene results in decreased expression of JAG1 mRNA
Methylcholanthrene results in increased expression of JAG1 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of JAG1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of JAG1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of JAG1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]		 CTD PMID:20713471 PMID:29094188 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO Methylcholanthrene results in decreased expression of JAK2 mRNA CTD PMID:22978700 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jph1 junctophilin 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to JPH1 promoter] CTD PMID:20348232 NCBI chr 5:2,030,227...2,137,171
Ensembl chr 5:2,030,281...2,125,284 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Methylcholanthrene results in increased expression of JUN mRNA CTD PMID:20713471 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Katnal2 katanin catalytic subunit A1 like 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KATNAL2 promoter] CTD PMID:20348232 NCBI chr18:70,531,759...70,607,886
Ensembl chr18:70,531,754...70,608,082 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 increases expression ISO Methylcholanthrene results in increased expression of KCNK2 mRNA CTD PMID:20713471 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases expression ISO Methylcholanthrene results in increased expression of KCNN4 mRNA CTD PMID:20713471 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Kctd1 potassium channel tetramerization domain containing 1 increases expression ISO Methylcholanthrene results in increased expression of KCTD1 mRNA CTD PMID:25926378 NCBI chr18:6,122,390...6,316,434
Ensembl chr18:6,122,390...6,317,393 		JBrowse link
G Kctd16 potassium channel tetramerization domain containing 16 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KCTD16 promoter] CTD PMID:20348232 NCBI chr18:32,166,236...32,473,067
Ensembl chr18:32,166,861...32,491,749 		JBrowse link
G Kctd3 potassium channel tetramerization domain containing 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KCTD3 promoter] CTD PMID:20348232 NCBI chr13:100,510,193...100,548,765
Ensembl chr13:100,510,195...100,548,718 		JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 decreases expression ISO Methylcholanthrene results in decreased expression of KCTD5 mRNA CTD PMID:20713471 NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209 		JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of KDR mRNA CTD PMID:25926378 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Methylcholanthrene results in increased expression of KEAP1 mRNA CTD PMID:23712962 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kif11 kinesin family member 11 increases expression
multiple interactions		 ISO
EXP		 Methylcholanthrene results in increased expression of KIF11 mRNA
Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of KIF11 mRNA]		 CTD PMID:20713471 PMID:26372666 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif18a kinesin family member 18A increases expression
multiple interactions		 ISO
EXP		 Methylcholanthrene results in increased expression of KIF18A mRNA
Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of KIF18A mRNA]		 CTD PMID:20713471 PMID:26372666 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Methylcholanthrene results in increased expression of KIF20A mRNA CTD PMID:20713471 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif22 kinesin family member 22 increases expression ISO Methylcholanthrene results in increased expression of KIF22 mRNA CTD PMID:20713471 NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401 		JBrowse link
G Kif23 kinesin family member 23 increases expression ISO Methylcholanthrene results in increased expression of KIF23 mRNA CTD PMID:20713471 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072 		JBrowse link
G Kif2c kinesin family member 2C increases expression ISO
EXP		 Methylcholanthrene results in increased expression of KIF2C mRNA CTD PMID:20713471 PMID:26372666 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase affects expression ISO Methylcholanthrene affects the expression of KIT mRNA CTD PMID:35487396 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kitlg KIT ligand increases expression ISO Methylcholanthrene results in increased expression of KITL mRNA CTD PMID:20713471 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression ISO Methylcholanthrene results in increased expression of KLF2 mRNA CTD PMID:20713471 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf5 KLF transcription factor 5 increases expression ISO Methylcholanthrene results in increased expression of KLF5 mRNA CTD PMID:20713471 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Klf9 KLF transcription factor 9 multiple interactions
decreases expression		 ISO Methylcholanthrene promotes the reaction [AHR protein binds to KLF9 promoter]
Methylcholanthrene results in decreased expression of KLF9 mRNA		 CTD PMID:20348232 PMID:23397585 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037 		JBrowse link
G Kmt2e lysine methyltransferase 2E increases expression ISO Methylcholanthrene results in increased expression of KMT2E mRNA CTD PMID:25926378 NCBI chr 4:11,658,218...11,727,373
Ensembl chr 4:11,658,979...11,727,373 		JBrowse link
G Kng1 kininogen 1 multiple interactions
decreases expression		 ISO AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 protein]
Methylcholanthrene results in decreased expression of KNG1 mRNA; Methylcholanthrene results in decreased expression of KNG1 protein		 CTD PMID:11549291 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein increases expression ISO Methylcholanthrene results in increased expression of KNSTRN mRNA CTD PMID:20713471 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715 		JBrowse link
G Kntc1 kinetochore associated 1 increases expression ISO Methylcholanthrene results in increased expression of KNTC1 mRNA CTD PMID:20713471 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 increases expression ISO Methylcholanthrene results in increased expression of KPNA2 mRNA CTD PMID:20713471 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions
increases mutagenesis		 ISO Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon]; Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon]
Methylcholanthrene results in increased mutagenesis of KRAS gene		 CTD PMID:11195466 PMID:16271038 PMID:20101149 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt75 keratin 75 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KRT75 promoter] CTD PMID:20348232 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345 		JBrowse link
G Lama4 laminin subunit alpha 4 decreases expression ISO Methylcholanthrene results in decreased expression of LAMA4 mRNA CTD PMID:29554273 NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347 		JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA CTD PMID:23519560 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451 		JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA CTD PMID:23519560 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases expression EXP Methylcholanthrene results in decreased expression of LCAT mRNA CTD PMID:11328961 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO Methylcholanthrene results in decreased expression of LDLR mRNA CTD PMID:35487396 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA CTD PMID:23519560 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lgals1 galectin 1 increases expression ISO Methylcholanthrene results in increased expression of LGALS1 mRNA CTD PMID:22579512 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lgals2 galectin 2 increases expression ISO Methylcholanthrene results in increased expression of LGALS2 mRNA CTD PMID:20713471 NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802 		JBrowse link
G Lgals3 galectin 3 increases expression ISO Methylcholanthrene results in increased expression of LGALS3 mRNA CTD PMID:20713471 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lgals8 galectin 8 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LGALS8 promoter] CTD PMID:20348232 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764 		JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LGI1 promoter] CTD PMID:20348232 NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of LIF mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to LIF promoter]		 CTD PMID:20348232 PMID:20713471 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lima1 LIM domain and actin binding 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LIMA1 promoter] CTD PMID:20348232 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473 		JBrowse link
G Lmnb1 lamin B1 increases expression ISO Methylcholanthrene results in increased expression of LMNB1 mRNA CTD PMID:20713471 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lmtk2 lemur tyrosine kinase 2 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of LMTK2 mRNA CTD PMID:25926378 NCBI chr12:10,426,772...10,508,750
Ensembl chr12:10,426,777...10,508,750 		JBrowse link
G Lox lysyl oxidase decreases expression ISO Methylcholanthrene results in decreased expression of LOX mRNA CTD PMID:20713471 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Lrp11 LDL receptor related protein 11 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LRP11 promoter] CTD PMID:20348232 NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110 		JBrowse link
G Lrr1 leucine rich repeat protein 1 increases expression ISO Methylcholanthrene results in increased expression of LRR1 mRNA CTD PMID:20713471 NCBI chr 6:87,643,195...87,651,894
Ensembl chr 6:87,643,217...87,651,894 		JBrowse link
G Lrrc8d leucine rich repeat containing 8 VRAC subunit D increases expression ISO Methylcholanthrene results in increased expression of LRRC8D mRNA CTD PMID:20713471 NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877 		JBrowse link
G Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression ISO Methylcholanthrene results in increased expression of LSM4 mRNA CTD PMID:20713471 NCBI chr16:18,755,481...18,761,106
Ensembl chr16:18,755,484...18,760,926 		JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LSM5 promoter] CTD PMID:20348232 NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165 		JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression ISO Methylcholanthrene results in increased expression of LSM6 mRNA CTD PMID:20713471 NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 increases expression ISO Methylcholanthrene results in increased expression of LTBP1 mRNA CTD PMID:20713471 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349 		JBrowse link
G Lum lumican decreases expression ISO Methylcholanthrene results in decreased expression of LUM mRNA CTD PMID:20713471 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A increases expression ISO Methylcholanthrene results in increased expression of LY6A mRNA CTD PMID:20713471 NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LY6E promoter] CTD PMID:20348232 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 increases expression ISO Methylcholanthrene results in increased expression of MAD1L1 mRNA CTD PMID:20713471 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAGI1 mRNA CTD PMID:23519560 NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO Methylcholanthrene results in increased expression of MAP2K1 mRNA CTD PMID:25926378 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO Methylcholanthrene results in increased expression of MAP2K3 mRNA CTD PMID:20713471 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression ISO Methylcholanthrene results in increased expression of MAPK1 mRNA CTD PMID:23712962 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Methylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16619036 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapkap1 MAPK associated protein 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MAPKAP1 promoter] CTD PMID:20348232 NCBI chr 3:17,715,813...17,918,387
Ensembl chr 3:17,715,834...17,918,384 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Methylcholanthrene results in decreased expression of MARCKS mRNA CTD PMID:20713471 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression ISO Methylcholanthrene results in increased expression of MASTL mRNA CTD PMID:20713471 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353 		JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression ISO Methylcholanthrene results in decreased expression of MAT1A mRNA CTD PMID:22100608 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Matn2 matrilin 2 decreases expression ISO Methylcholanthrene results in decreased expression of MATN2 mRNA CTD PMID:20713471 NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113 		JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MBNL1 promoter] CTD PMID:20348232 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368 		JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression ISO Methylcholanthrene results in increased expression of MCM10 mRNA CTD PMID:20713471 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO Methylcholanthrene results in increased expression of MCM3 mRNA CTD PMID:20713471 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO Methylcholanthrene results in increased expression of MCM4 mRNA CTD PMID:20713471 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression ISO Methylcholanthrene results in increased expression of MCM5 mRNA CTD PMID:20713471 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO Methylcholanthrene results in increased expression of MCM6 mRNA CTD PMID:20713471 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Med13l mediator complex subunit 13L multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter] CTD PMID:20348232 NCBI chr12:37,807,596...38,004,886
Ensembl chr12:37,808,285...38,004,473 		JBrowse link
G Melk maternal embryonic leucine zipper kinase increases expression ISO Methylcholanthrene results in increased expression of MELK mRNA CTD PMID:20713471 NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter] CTD PMID:20348232 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression ISO Methylcholanthrene results in increased expression of MFAP3L mRNA CTD PMID:20713471 NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MGST2 promoter] CTD PMID:20348232 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Mid1 midline 1 decreases expression ISO Methylcholanthrene results in decreased expression of MID1 mRNA CTD PMID:20713471 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Mideas mitotic deacetylase associated SANT domain protein multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter] CTD PMID:20348232 NCBI chr 6:103,784,779...103,854,470
Ensembl chr 6:103,787,873...103,829,178 		JBrowse link
G Mir101-2 microRNA 101-2 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR101B mRNA CTD PMID:25926378 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir122 microRNA 122 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR122 mRNA CTD PMID:25926378 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir130a microRNA 130a affects expression ISO Methylcholanthrene affects the expression of MIR130A mRNA CTD PMID:25926378 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir130b microRNA 130b decreases expression ISO Methylcholanthrene results in decreased expression of MIR130B mRNA CTD PMID:25926378 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Mir144 microRNA 144 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR144 mRNA CTD PMID:25926378 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir145 microRNA 145 decreases expression ISO Methylcholanthrene results in decreased expression of MIR145A mRNA CTD PMID:25926378 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir191 microRNA 191 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR191 mRNA CTD PMID:25926378 NCBI chr 8:109,264,098...109,264,188 JBrowse link
G Mir19a microRNA 19a multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR19A mRNA CTD PMID:25926378 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR206 mRNA CTD PMID:25926378 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mir210 microRNA 210 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR210 mRNA CTD PMID:25926378 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir211 microRNA 211 decreases expression ISO Methylcholanthrene results in decreased expression of MIR211 mRNA CTD PMID:25926378 NCBI chr 1:117,777,539...117,777,644
Ensembl chr 1:117,777,539...117,777,644 		JBrowse link
G Mir32 microRNA 32 decreases expression
multiple interactions		 ISO Methylcholanthrene results in decreased expression of MIR32 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR32 mRNA		 CTD PMID:25926378 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152 		JBrowse link
G Mir340-1 microRNA 340-1 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR340 mRNA CTD PMID:25926378 NCBI chr10:34,393,568...34,393,665
Ensembl chr10:34,393,568...34,393,665 		JBrowse link
G Mir345 microRNA 345 affects expression
multiple interactions		 ISO Methylcholanthrene affects the expression of MIR345 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR345 mRNA		 CTD PMID:25926378 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir3545 microRNA 3545 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR203 mRNA CTD PMID:25926378 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656 		JBrowse link
G Mir425 microRNA 425 decreases expression ISO Methylcholanthrene results in decreased expression of MIR425 mRNA CTD PMID:25926378 NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637 		JBrowse link
G Mir449a microRNA 449a multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR449A mRNA CTD PMID:25926378 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804 		JBrowse link
G Mir497 microRNA 497 increases expression ISO Methylcholanthrene results in increased expression of MIR497 mRNA CTD PMID:25926378 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir92a2 microRNA 92a-2 decreases expression ISO Methylcholanthrene results in decreased expression of MIR92-2 mRNA CTD PMID:25926378 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression
multiple interactions		 ISO
EXP		 Methylcholanthrene results in increased expression of MKI67 mRNA
Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of MKI67 mRNA]; Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of MKI67 protein]		 CTD PMID:20713471 PMID:26372666 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mllt6 MLLT6, PHD finger containing multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MLLT6 promoter] CTD PMID:20348232 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073 		JBrowse link
G Mlph melanophilin multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MLPH promoter] CTD PMID:20348232 NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Methylcholanthrene results in increased expression of MMP1 mRNA CTD PMID:29554273 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
decreases expression		 ISO Methylcholanthrene results in increased expression of MMP13 mRNA
Methylcholanthrene results in decreased expression of MMP13 mRNA		 CTD PMID:20713471 PMID:29554273 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of MMP2 mRNA; [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of MMP2 protein CTD PMID:12015029 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Methylcholanthrene results in increased expression of MMP3 mRNA CTD PMID:20713471 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression		 ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MMP9 mRNA
Methylcholanthrene results in decreased expression of MMP9 mRNA		 CTD PMID:23519560 PMID:29554273 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpi mannose phosphate isomerase multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MPI promoter] CTD PMID:20348232 NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150 		JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MPL mRNA CTD PMID:25926378 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797 		JBrowse link
G Mrtfb myocardin related transcription factor B multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MRTFB promoter] CTD PMID:20348232 NCBI chr10:1,116,315...1,278,106
Ensembl chr10:1,116,310...1,277,897 		JBrowse link
G Ms4a7 membrane spanning 4-domains A7 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MS4A7 promoter] CTD PMID:20348232 NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260 		JBrowse link
G Msh4 mutS homolog 4 decreases expression ISO Methylcholanthrene results in decreased expression of MSH4 mRNA CTD PMID:35487396 NCBI chr 2:242,785,392...242,844,609
Ensembl chr 2:242,792,661...242,843,487 		JBrowse link
G Msh5 mutS homolog 5 decreases expression ISO Methylcholanthrene results in decreased expression of MSH5 mRNA CTD PMID:35487396 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336 		JBrowse link
G Msln mesothelin increases expression ISO Methylcholanthrene results in increased expression of MSLN mRNA CTD PMID:20713471 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Msmb microseminoprotein, beta multiple interactions
affects binding
increases expression		 ISO
EXP		 Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter]
Methylcholanthrene binds to MSMB protein
Methylcholanthrene results in increased expression of MSMB mRNA		 CTD PMID:3940634 PMID:20348232 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO Methylcholanthrene results in decreased expression of MSMO1 mRNA CTD PMID:20713471 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression		 ISO AHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]; NR3C1 protein affects the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA] CTD PMID:23994556 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtcl3 MTCL family member 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MTCL3 promoter] CTD PMID:20348232 NCBI chr 1:28,629,036...28,701,416
Ensembl chr 1:28,620,293...28,701,796 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MTHFD2 mRNA CTD PMID:25926378 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO Methylcholanthrene results in decreased expression of MX2 mRNA CTD PMID:20713471 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342 		JBrowse link
G Mybl1 MYB proto-oncogene like 1 affects expression ISO Methylcholanthrene affects the expression of MYBL1 mRNA CTD PMID:35487396 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO Methylcholanthrene results in decreased expression of MYBL2 mRNA CTD PMID:35487396 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MYH7 mRNA CTD PMID:25926378 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Myl9 myosin light chain 9 decreases expression
multiple interactions		 ISO Methylcholanthrene results in decreased expression of MYL9 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MYL9 mRNA		 CTD PMID:20713471 PMID:25926378 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MYLK mRNA CTD PMID:23519560 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Myo1d myosin ID decreases expression ISO Methylcholanthrene results in decreased expression of MYO1D mRNA CTD PMID:20713471 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349 		JBrowse link
G Myo7a myosin VIIA decreases expression ISO Methylcholanthrene results in decreased expression of MYO7A mRNA CTD PMID:20713471 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157 		JBrowse link
G Myof myoferlin multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MYOF promoter] CTD PMID:20348232 NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334 		JBrowse link
G Myom2 myomesin 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MYOM2 promoter] CTD PMID:20348232 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Nasp nuclear autoantigenic sperm protein increases expression ISO Methylcholanthrene results in increased expression of NASP mRNA CTD PMID:20713471 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 decreases expression ISO Methylcholanthrene results in decreased expression of NCAM1 mRNA CTD PMID:20713471 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 increases expression ISO Methylcholanthrene results in increased expression of NCAPG2 mRNA CTD PMID:20713471 NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO Methylcholanthrene results in increased expression of NCAPH mRNA CTD PMID:20713471 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression ISO Methylcholanthrene results in increased expression of NCF1 mRNA CTD PMID:19559082 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nck2 NCK adaptor protein 2 decreases expression ISO Methylcholanthrene results in decreased expression of NCK2 mRNA CTD PMID:20713471 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression
increases expression		 ISO Methylcholanthrene results in decreased expression of NDC80 mRNA
Methylcholanthrene results in increased expression of NDC80 mRNA		 CTD PMID:20713471 PMID:22579512 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Ndrg4 NDRG family member 4 increases expression ISO Methylcholanthrene results in increased expression of NDRG4 mRNA CTD PMID:20713471 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to NDST1 promoter] CTD PMID:20348232 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO Methylcholanthrene results in increased expression of NEDD9 mRNA CTD PMID:16619036 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nek2 NIMA-related kinase 2 increases expression ISO Methylcholanthrene results in increased expression of NEK2 mRNA CTD PMID:20713471 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nelfcd negative elongation factor complex member C/D multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to NELFCD promoter] CTD PMID:20348232 NCBI chr 3:163,213,765...163,224,886
Ensembl chr 3:163,213,762...163,224,884 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 decreases expression ISO Methylcholanthrene results in decreased expression of NFATC2 mRNA CTD PMID:29554273 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of NFE2L2 mRNA; Methylcholanthrene results in increased expression of NFE2L2 protein
Methylcholanthrene promotes the reaction [AHR protein binds to NFE2L2 promoter]
NFE2L2 protein affects the reaction [Methylcholanthrene results in increased expression of PSMB5 mRNA]		 CTD PMID:16723119 PMID:20348232 PMID:20713471 PMID:23712962 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO Methylcholanthrene results in increased expression of NFKBIA mRNA CTD PMID:29554273 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Methylcholanthrene results in increased expression of NFKBIZ mRNA CTD PMID:20713471 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nfya nuclear transcription factor Y subunit alpha multiple interactions
increases activity		 ISO Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon]
Methylcholanthrene results in increased activity of NFYA protein		 CTD PMID:16271038 NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898 		JBrowse link
G Ngf nerve growth factor increases expression
multiple interactions		 ISO Methylcholanthrene results in increased expression of NGF mRNA
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA		 CTD PMID:20713471 PMID:23519560 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 decreases expression ISO Methylcholanthrene results in decreased expression of NHERF2 mRNA