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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:versicolorin A
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Accession:CHEBI:72676 term browser browse the term
Definition:An organic heteropentacyclic compound that is 3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione carrying three hydroxy substituents at positions 4, 6 and 8.
Synonyms:exact_synonym: (3aS,12aR)-4,6,8-trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione
 related_synonym: Formula=C18H10O7;   InChI=1S/C18H10O7/c19-6-3-8-12(10(20)4-6)16(22)14-9(15(8)21)5-11-13(17(14)23)7-1-2-24-18(7)25-11/h1-5,7,18-20,23H/t7-,18+/m0/s1;   InChIKey=SJNDYXPJRUTLNW-ULCDLSAGSA-N;   SMILES=[H][C@]12OC=C[C@@]1([H])c1c(O)c3C(=O)c4c(O)cc(O)cc4C(=O)c3cc1O2;   Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione
 xref: CAS:6807-96-1
 xref_mesh: MESH:C029826
 xref: MetaCyc:CPD-10176;   PMID:16461654;   PMID:22103394;   PMID:22648070;   PMID:3923331;   PMID:655714;   PMID:6803669;   PMID:6929388;   PMID:7356313;   PMID:7425622;   PMID:7486998;   PMID:8999832;   Reaxys:1441532
 cyclic_relationship: is_conjugate_acid_of CHEBI:77976


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versicolorin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 decreases expression ISO versicolorin A results in decreased expression of AKAP13 mRNA CTD PMID:32106047 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Alyref Aly/REF export factor increases expression ISO versicolorin A results in increased expression of ALYREF mRNA CTD PMID:32106047 NCBI chr10:109,768,593...109,774,639
Ensembl chr10:109,770,876...109,774,639
JBrowse link
G Aoc3 amine oxidase, copper containing 3 increases expression ISO versicolorin A results in increased expression of AOC3 mRNA CTD PMID:32106047 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Ccdc168 coiled-coil domain containing 168 increases expression ISO versicolorin A results in increased expression of CCDC168 mRNA CTD PMID:32106047 NCBI chr 9:50,814,067...50,851,997 JBrowse link
G Cfp complement factor properdin increases expression ISO versicolorin A results in increased expression of CFP mRNA CTD PMID:32106047 NCBI chr  X:1,311,121...1,316,683
Ensembl chr  X:1,311,121...1,316,682
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO versicolorin A results in increased phosphorylation of CHEK1 protein CTD PMID:32106047 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Clec3b C-type lectin domain family 3, member B increases expression ISO versicolorin A results in increased expression of CLEC3B mRNA CTD PMID:32106047 NCBI chr 8:132,241,016...132,248,066
Ensembl chr 8:132,241,134...132,246,694
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO versicolorin A results in increased expression of CYP1A1 mRNA CTD PMID:32106047 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO versicolorin A results in increased expression of CYP1A2 mRNA CTD PMID:32106047 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Eloa elongin A increases expression ISO versicolorin A results in increased expression of TCEB3 mRNA CTD PMID:32106047 NCBI chr 5:154,348,167...154,363,324
Ensembl chr 5:154,347,391...154,363,329
JBrowse link
G Elob elongin B increases expression ISO versicolorin A results in increased expression of TCEB2 mRNA CTD PMID:32106047 NCBI chr10:13,163,032...13,168,217
Ensembl chr10:13,163,036...13,168,217
JBrowse link
G Erich2 glutamate-rich 2 increases expression ISO versicolorin A results in increased expression of ERICH2 mRNA CTD PMID:32106047 NCBI chr 3:56,801,387...56,839,435
Ensembl chr 3:56,802,714...56,838,918
JBrowse link
G Fam90a1 family with sequence similarity 90, member A1 increases expression ISO versicolorin A results in increased expression of FAM90A1 mRNA CTD PMID:32106047 NCBI chr16:75,001,033...75,016,173 JBrowse link
G Fbll1 fibrillarin-like 1 increases expression ISO versicolorin A results in increased expression of FBLL1 mRNA CTD PMID:32106047 NCBI chr10:20,620,957...20,622,600
Ensembl chr10:20,620,957...20,622,600
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 decreases expression ISO versicolorin A results in decreased expression of FCHSD2 mRNA CTD PMID:32106047 NCBI chr 1:166,140,025...166,395,915
Ensembl chr 1:166,125,474...166,395,915
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO versicolorin A results in increased expression of GADD45B mRNA CTD PMID:32106047 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G H1f1 H1.1 linker histone, cluster member increases expression ISO versicolorin A results in increased expression of H1-1 mRNA CTD PMID:32106047 NCBI chr17:43,614,101...43,614,844
Ensembl chr17:43,614,101...43,614,844
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO versicolorin A results in decreased expression of H1-4 mRNA CTD PMID:32106047 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO versicolorin A results in decreased expression of H1-5 mRNA CTD PMID:32106047 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H1f6 H1.6 linker histone, cluster member increases expression ISO versicolorin A results in increased expression of H1-6 mRNA CTD PMID:32106047 NCBI chr17:43,675,190...43,675,934
Ensembl chr17:43,675,190...43,675,934
JBrowse link
G H2ac4 H2A clustered histone 4 decreases expression ISO versicolorin A results in decreased expression of H2AC4 mRNA CTD PMID:32106047 NCBI chr17:44,840,990...44,841,382
Ensembl chr17:44,840,990...44,841,382
JBrowse link
G H2ax H2A.X variant histone increases expression ISO versicolorin A results in increased expression of H2AX protein CTD PMID:32106047 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO versicolorin A results in decreased expression of H4C3 mRNA CTD PMID:32106047 NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO versicolorin A results in decreased expression of H1-3 mRNA CTD PMID:32106047 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO versicolorin A results in increased expression of HBEGF mRNA CTD PMID:32106047 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H decreases expression ISO versicolorin A results in decreased expression of H2AC11 mRNA; versicolorin A results in decreased expression of HIST1H2AH mRNA CTD PMID:32106047 NCBI chr17:43,632,354...43,632,851
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Hist1h3b histone cluster 1, H3b decreases expression ISO versicolorin A results in decreased expression of HIST1H3B mRNA CTD PMID:32106047 NCBI chr17:44,760,023...44,764,058
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
Ensembl chr17:44,839,721...44,840,131
JBrowse link
G Hist1h4b histone cluster 1 H4 family member B decreases expression ISO versicolorin A results in decreased expression of HIST1H4A mRNA; versicolorin A results in decreased expression of HIST1H4B mRNA CTD PMID:32106047 NCBI chr17:44,522,144...44,526,587
Ensembl chr17:44,522,140...44,526,583
JBrowse link
G Klf12 Kruppel-like factor 12 decreases expression ISO versicolorin A results in decreased expression of KLF12 mRNA CTD PMID:32106047 NCBI chr15:84,316,986...84,748,549
Ensembl chr15:84,324,470...84,748,525
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression ISO versicolorin A results in increased expression of MAFB mRNA CTD PMID:32106047 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Mia MIA SH3 domain containing increases expression ISO versicolorin A results in increased expression of MIA mRNA CTD PMID:32106047 NCBI chr 1:83,991,577...83,993,270
Ensembl chr 1:83,991,578...83,993,270
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO versicolorin A results in decreased expression of CYTB mRNA CTD PMID:32106047 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mvb12b multivesicular body subunit 12B decreases expression ISO versicolorin A results in decreased expression of MVB12B mRNA CTD PMID:32106047 NCBI chr 3:12,780,196...12,944,542
Ensembl chr 3:12,780,100...12,944,494
JBrowse link
G Nxf1 nuclear RNA export factor 1 increases expression ISO versicolorin A results in increased expression of NXF1 mRNA CTD PMID:32106047 NCBI chr 1:224,957,535...224,970,728
Ensembl chr 1:224,957,517...224,970,727
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 increases expression ISO versicolorin A results in increased expression of NXT2 mRNA CTD PMID:32106047 NCBI chr  X:113,509,841...113,517,112
Ensembl chr  X:113,510,621...113,517,102
JBrowse link
G Papola poly (A) polymerase alpha increases expression ISO versicolorin A results in increased expression of PAPOLA mRNA CTD PMID:32106047 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO versicolorin A results in increased expression of PMAIP1 mRNA CTD PMID:32106047 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Polr2a RNA polymerase II subunit A increases expression ISO versicolorin A results in increased expression of POLR2A mRNA CTD PMID:32106047 NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
JBrowse link
G Polr2h RNA polymerase II, I and III subunit H increases expression ISO versicolorin A results in increased expression of POLR2H mRNA CTD PMID:32106047 NCBI chr11:83,877,760...83,882,208
Ensembl chr11:83,878,006...83,882,117
Ensembl chr11:83,878,006...83,882,117
JBrowse link
G Polr2k RNA polymerase II, I and III subunit K increases expression ISO versicolorin A results in increased expression of POLR2K mRNA CTD PMID:32106047 NCBI chr 7:74,939,010...74,992,594
Ensembl chr 7:74,989,223...74,992,582
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO versicolorin A results in decreased expression of ROR1 mRNA CTD PMID:32106047 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
JBrowse link
G Sbsn suprabasin increases expression ISO versicolorin A results in increased expression of SBSN mRNA CTD PMID:32106047 NCBI chr 1:89,202,527...89,206,994
Ensembl chr 1:89,202,527...89,206,994
JBrowse link
G Sncaip synuclein, alpha interacting protein decreases expression ISO versicolorin A results in decreased expression of SNCAIP mRNA CTD PMID:32106047 NCBI chr18:47,739,284...47,877,679
Ensembl chr18:47,739,140...47,877,676
JBrowse link
G Snora19 small nucleolar RNA, H/ACA box 19 increases expression ISO versicolorin A results in increased expression of SNORA19 mRNA CTD PMID:32106047 NCBI chr 7:66,663,841...66,663,909
Ensembl chr 7:66,663,842...66,663,967
JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression ISO versicolorin A results in decreased expression of SNORA58 mRNA CTD PMID:32106047 NCBI chr 6:111,468,732...111,468,807
Ensembl chr 6:111,468,732...111,468,807
JBrowse link
G Snrnp48 small nuclear ribonucleoprotein U11/U12 subunit 48 increases expression ISO versicolorin A results in increased expression of SNRNP48 mRNA CTD PMID:32106047 NCBI chr17:27,243,732...27,279,271
Ensembl chr17:27,243,781...27,279,260
JBrowse link
G Spef1 sperm flagellar 1 increases expression ISO versicolorin A results in increased expression of SPEF1 mRNA CTD PMID:32106047 NCBI chr 3:123,712,907...123,720,787
Ensembl chr 3:123,714,564...123,718,432
JBrowse link
G Tcea1 transcription elongation factor A1 increases expression ISO versicolorin A results in increased expression of TCEA1 mRNA CTD PMID:32106047 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429
JBrowse link
G Tesmin testis expressed metallothionein like protein increases expression ISO versicolorin A results in increased expression of TESMIN mRNA CTD PMID:32106047 NCBI chr 1:218,632,764...218,651,054
Ensembl chr 1:218,632,764...218,651,053
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation ISO versicolorin A results in increased phosphorylation of TP53 protein CTD PMID:32106047 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay increases expression ISO versicolorin A results in increased expression of UPF3B mRNA CTD PMID:32106047 NCBI chr  X:123,713,327...123,731,431
Ensembl chr  X:123,713,339...123,731,385
JBrowse link
G Vmo1 vitelline membrane outer layer 1 homolog increases expression ISO versicolorin A results in increased expression of VMO1 mRNA CTD PMID:32106047 NCBI chr10:57,120,499...57,121,584
Ensembl chr10:57,120,499...57,121,584
JBrowse link
G Zdhhc14 zinc finger DHHC-type palmitoyltransferase 14 decreases expression ISO versicolorin A results in decreased expression of ZDHHC14 mRNA CTD PMID:32106047 NCBI chr 1:46,378,807...46,658,527
Ensembl chr 1:46,378,807...46,649,292
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 decreases expression ISO versicolorin A results in decreased expression of ZMIZ1 mRNA CTD PMID:32106047 NCBI chr16:1,749,191...1,954,633
Ensembl chr16:1,749,191...1,954,614
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 decreases expression ISO versicolorin A results in decreased expression of ZMYND8 mRNA CTD PMID:32106047 NCBI chr 3:162,480,766...162,594,145
Ensembl chr 3:162,480,804...162,581,610
JBrowse link
G Znrf3 zinc and ring finger 3 decreases expression ISO versicolorin A results in decreased expression of ZNRF3 mRNA CTD PMID:32106047 NCBI chr14:85,527,099...85,586,294 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19773
    role 19719
      biological role 19719
        aetiopathogenetic role 18973
          carcinogenic agent 18363
            versicolorin A 56
              (4S,8R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.0(3,10).0(4,8).0(14,19)]icosa-1(12),2,5,10,13,16,19-heptaen-18-one 0
              (4S,8R,16R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.0(3,10).0(4,8).0(14,19)]icosa-1(12),2,5,10,13,19-hexaen-18-one 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19579
                        carbon atom 19569
                          organic molecular entity 19569
                            organic group 18613
                              organic divalent group 18604
                                organodiyl group 18604
                                  carbonyl group 18521
                                    carbonyl compound 18521
                                      ketone 16833
                                        cyclic ketone 15251
                                          quinone 8380
                                            p-quinones 8287
                                              versicolorin A 56
                                                (4S,8R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.0(3,10).0(4,8).0(14,19)]icosa-1(12),2,5,10,13,16,19-heptaen-18-one 0
                                                (4S,8R,16R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.0(3,10).0(4,8).0(14,19)]icosa-1(12),2,5,10,13,19-hexaen-18-one 0
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