Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenoxybenzoic acid
go back to main search page
Accession:CHEBI:72633 term browser browse the term
Definition:An aromatic ether that is diphenyl ether in which one of the hydrogens is replaced by a carboxy group.
Synonyms:related_synonym: carboxydiphenyl ether;   carboxydiphenyl ethers;   phenoxybenzoic acids



show annotations for term's descendants           Sort by:
3-phenoxybenzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor decreases activity
multiple interactions
ISO 3-phenoxybenzoic acid results in decreased activity of AR protein
[Dihydrotestosterone co-treated with 3-phenoxybenzoic acid] results in decreased expression of AR mRNA
CTD PMID:16857237 PMID:20410157 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 3-phenoxybenzoic acid results in increased expression of BAX mRNA CTD PMID:29945211 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Casp3 caspase 3 increases activity ISO 3-phenoxybenzoic acid results in increased activity of CASP3 protein CTD PMID:29945211 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid results in increased expression of CASP9 mRNA] CTD PMID:29945211 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions ISO 3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]] CTD PMID:29945211 NCBI chr15:32,139,716...32,141,476
Ensembl chr15:32,139,716...32,141,476
JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CRH mRNA CTD PMID:32518293 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CRHR1 mRNA CTD PMID:32518293 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466
JBrowse link
G Csf3r colony stimulating factor 3 receptor multiple interactions ISO 3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]] CTD PMID:29945211 NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP11A1 mRNA CTD PMID:32518293 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects binding ISO 3-phenoxybenzoic acid binds to CYP1A2 protein CTD PMID:32278787 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP 3-phenoxybenzoic acid results in increased expression of CYP4A1 mRNA CTD PMID:32040184 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231
JBrowse link
G Esr1 estrogen receptor 1 decreases activity
multiple interactions
EXP
ISO
3-phenoxybenzoic acid results in decreased activity of ESR1 protein
3-phenoxybenzoic acid inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]
CTD PMID:20410157 PMID:24388911 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ESR2 mRNA CTD PMID:32518293 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FKBP5 mRNA CTD PMID:32518293 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIN2B mRNA CTD PMID:32518293 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects binding ISO 3-phenoxybenzoic acid binds to GSTP1 protein CTD PMID:32278787 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of HTR1A mRNA CTD PMID:32518293 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HTR2A mRNA CTD PMID:32518293 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO 3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of ITGAM mRNA]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of ITGAM mRNA]] CTD PMID:29945211 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
JBrowse link
G Mc2r melanocortin 2 receptor multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of MC2R mRNA CTD PMID:32518293 NCBI chr18:64,279,878...64,291,775
Ensembl chr18:64,277,360...64,291,881
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO 3-phenoxybenzoic acid inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein]
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NR3C1 mRNA
CTD PMID:26647222 PMID:32518293 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NR3C2 mRNA CTD PMID:32518293 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXT mRNA CTD PMID:32518293 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:138,235,754...138,236,594
JBrowse link
G Oxtr oxytocin receptor multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXTR mRNA CTD PMID:32518293 NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP 3-phenoxybenzoic acid inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP 3-phenoxybenzoic acid binds to and results in increased activity of PPARA protein CTD PMID:31538121 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO 3-phenoxybenzoic acid binds to RORA protein CTD PMID:32278787 NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO 3-phenoxybenzoic acid binds to RORC protein CTD PMID:32278787 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566
JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO 3-phenoxybenzoic acid binds to RXRG protein CTD PMID:32278787 NCBI chr13:82,276,330...82,318,097
Ensembl chr13:82,276,291...82,318,095
JBrowse link
G Spi1 Spi-1 proto-oncogene multiple interactions ISO 3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of SPI1 mRNA]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of SPI1 mRNA]] CTD PMID:29945211 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 3-phenoxybenzoic acid results in increased expression of TFF1 mRNA CTD PMID:20397420 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO 3-phenoxybenzoic acid inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:26647222 NCBI chr  X:109,006,410...109,066,389
Ensembl chr  X:109,006,420...109,015,519
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [Insecticides results in increased abundance of 3-phenoxybenzoic acid] which results in increased expression of TSHB protein CTD PMID:31284115 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984
JBrowse link
G Vdr vitamin D receptor affects binding ISO 3-phenoxybenzoic acid binds to VDR protein CTD PMID:32278787 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        biochemical role 20264
          metabolite 20245
            eukaryotic metabolite 19958
              plant metabolite 18270
                diphenyl ether 4214
                  phenoxybenzoic acid 34
                    2-phenoxybenzoic acid 0
                    3-phenoxybenzoic acid 34
                    4-phenoxybenzoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      aromatic carboxylic acid 14051
                                        benzoic acids 14017
                                          phenoxybenzoic acid 34
                                            2-phenoxybenzoic acid 0
                                            3-phenoxybenzoic acid 34
                                            4-phenoxybenzoic acid 0
paths to the root