semisynthetic derivative - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	semisynthetic derivative	go back to main search page
Accession:	CHEBI:72588	browse the term
Definition:	Any organic molecular entity derived from a natural product by partial chemical synthesis.
Synonyms:	related_synonym:	semi-synthetic compound; semi-synthetic compounds; semi-synthetic derivative; semi-synthetic derivatives; semisynthetic compound; semisynthetic compounds; semisynthetic derivatives
	xref:	Wikipedia:Semisynthesis

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Rat (1648) Mouse (1652) Human (1676) Chinchilla (0) Bonobo (0) Dog (3) Squirrel (0) Pig (9) Green Monkey (0) Naked Mole-rat (0) All
Genes (1648)

(E)-roxithromycin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2, apoptosis regulator

decreases expression

Roxithromycin results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases activity

Roxithromycin results in decreased activity of CYP2B6 protein

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
decreases expression
decreases activity

Roxithromycin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]
Roxithromycin results in decreased expression of CYP3A4 mRNA
Roxithromycin results in decreased activity of CYP3A4 protein

PMID:16416302 PMID:16837568 PMID:17164692

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

Fas ligand

increases expression

Roxithromycin results in increased expression of FASLG protein

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

Roxithromycin results in increased expression of FOS mRNA; Roxithromycin results in increased expression of FOS protein

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

interleukin 1 beta

multiple interactions

Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL1B mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL1B protein]
Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]

PMID:17524151 PMID:18197913

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL6 mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

integrin subunit beta 4

decreases expression

Roxithromycin results in decreased expression of ITGB4 protein

NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012

G

laminin subunit gamma 2

decreases expression

Roxithromycin results in decreased expression of LAMC2 protein

NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200

G

mucin 5AC, oligomeric mucus/gel-forming

multiple interactions

Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC protein]

NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475

G

nuclear factor kappa B subunit 1

multiple interactions

Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]]

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nitric oxide synthase 2

multiple interactions

Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of NOS2 protein]
Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of NOS2 protein]

PMID:16061884 PMID:17524151

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

Roxithromycin inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

tumor necrosis factor

multiple interactions

Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of TNF mRNA]; Roxithromycin inhibits the reaction [Mustard Gas results in increased expression of TNF protein]
Roxithromycin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]

PMID:17524151 PMID:18197913

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

artemether

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

[Artemether co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

nuclear receptor subfamily 1, group I, member 3

affects expression
multiple interactions

artemether affects the expression of NR1I3 mRNA alternative form
[Artemether co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; Artemether binds to and results in increased activity of NR1I3 protein alternative form

PMID:24721719 PMID:31312845

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

prolactin

increases secretion

Artemether results in increased secretion of PRL protein

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

artesunate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin alpha 2, smooth muscle

multiple interactions
decreases expression

Deferoxamine inhibits the reaction [Artesunate results in decreased expression of ACTA2 mRNA]
Artesunate results in decreased expression of ACTA2 mRNA; Artesunate results in decreased expression of ACTA2 protein
Artesunate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

apoptosis inducing factor, mitochondria associated 1

affects localization

artesunate affects the localization of AIFM1 protein

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

androgen receptor

multiple interactions

artesunate binds to and results in decreased activity of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

autophagy related 12

increases expression

Artesunate results in increased expression of ATG12 mRNA

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 3

increases expression

Artesunate results in increased expression of ATG3 mRNA

NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224

G

autophagy related 5

increases expression

Artesunate results in increased expression of ATG5 mRNA

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

Artesunate results in increased expression of BAX protein
[1,2-Dimethylhydrazine co-treated with artesunate] results in increased expression of BAX protein

PMID:24704559 PMID:29031619 PMID:33002460

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

decreases expression
multiple interactions

Artesunate results in decreased expression of BCL2 protein
3-methyladenine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; acadesine promotes the reaction [Artesunate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; dorsomorphin inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; Sirolimus promotes the reaction [Artesunate results in decreased expression of BCL2 protein]
[1,2-Dimethylhydrazine co-treated with artesunate] results in decreased expression of BCL2 protein

PMID:24704559 PMID:29031619 PMID:33002460

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

bone marrow stromal cell antigen 1

increases response to substance

BST1 mRNA results in increased susceptibility to artesunate

NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180

G

caspase 3

increases activity
increases cleavage
multiple interactions

artesunate results in increased activity of CASP3 protein
Artesunate results in increased cleavage of CASP3 protein
3-methyladenine inhibits the reaction [Artesunate results in increased cleavage of CASP3 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [Artesunate results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Artesunate results in increased cleavage of CASP3 protein]

PMID:19513562 PMID:24704559 PMID:33002460

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

affects expression

artesunate affects the expression of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

increases expression
decreases response to substance

artesunate results in increased expression of CAT protein
CAT protein results in decreased susceptibility to artesunate

PMID:19513562 PMID:20144594

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cyclin D1

decreases expression

Artesunate results in decreased expression of CCND1 protein

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin E1

decreases expression

Artesunate results in decreased expression of CCNE1 protein

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

chaperonin containing TCP1 subunit 2

decreases response to substance

CCT2 mRNA results in decreased susceptibility to artesunate

NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944

G

cyclin dependent kinase 2

decreases expression

Artesunate results in decreased expression of CDK2 protein

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

decreases expression

Artesunate results in decreased expression of CDK4 protein

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

checkpoint kinase 1

multiple interactions
increases phosphorylation

APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of CHEK1 protein]

NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009

G

checkpoint kinase 2

multiple interactions
increases phosphorylation

APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of CHEK2 protein]

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

CAP-GLY domain containing linker protein family, member 4

increases response to substance

CLIP4 mRNA results in increased susceptibility to artesunate

NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874

G

coenzyme Q8A

decreases response to substance

COQ8A mRNA results in decreased susceptibility to artesunate

NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431

G

catenin beta 1

multiple interactions

artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of CTNNB1 protein]

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

dopamine beta-hydroxylase

increases response to substance

DBH mRNA results in increased susceptibility to artesunate

NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248

G

desmin

multiple interactions
decreases expression

Deferoxamine inhibits the reaction [Artesunate results in decreased expression of DES mRNA]
Artesunate results in decreased expression of DES mRNA; Artesunate results in decreased expression of DES protein

NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699

G

estrogen receptor 1

multiple interactions

artesunate binds to and results in decreased activity of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

Fas cell surface death receptor

increases expression

artesunate results in increased expression of FAS protein

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

filamin A

increases response to substance

FLNA mRNA results in increased susceptibility to artesunate

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

fibronectin 1

multiple interactions
decreases expression

Deferoxamine inhibits the reaction [Artesunate results in decreased expression of FN1 mRNA]
Artesunate results in decreased expression of FN1 mRNA; Artesunate results in decreased expression of FN1 protein

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

ferritin heavy chain 1

decreases expression
multiple interactions

Artesunate results in decreased expression of FTH1 mRNA; Artesunate results in decreased expression of FTH1 protein
Chloroquine inhibits the reaction [Artesunate results in decreased expression of FTH1 mRNA]

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

frizzled class receptor 7

increases response to substance

FZD7 mRNA results in increased susceptibility to artesunate

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

glutamate-cysteine ligase, catalytic subunit

affects response to substance
decreases response to substance

GCLC mRNA affects the susceptibility to artesunate
GCLC mRNA results in decreased susceptibility to artesunate

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

decreases response to substance

GCLM mRNA results in decreased susceptibility to artesunate

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glutathione peroxidase 4

decreases activity
multiple interactions

Artesunate results in decreased activity of GPX4 protein
Artesunate inhibits the reaction [Carbon Tetrachloride results in increased expression of GPX4 protein]

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

glutathione S-transferase mu 4

affects response to substance

GSTM4 mRNA affects the susceptibility to artesunate

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase pi 1

decreases expression

artesunate results in decreased expression of GSTP1 protein

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 2

affects response to substance

GSTT2 mRNA affects the susceptibility to artesunate

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

glutathione S-transferase zeta 1

affects response to substance

GSTZ1 mRNA affects the susceptibility to artesunate

NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284

G

H2A.X variant histone

multiple interactions
increases phosphorylation

APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of H2AX protein]

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239

G

interleukin 1 beta

multiple interactions

Artesunate inhibits the reaction [Ethanol results in increased expression of IL1B protein]; Artesunate inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL1B protein]

PMID:27474069 PMID:30031708

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

Artesunate inhibits the reaction [Ethanol results in increased expression of IL6 protein]; Artesunate inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL6 protein]

PMID:27474069 PMID:30031708

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

integrin subunit beta 1

increases response to substance

ITGB1 mRNA results in increased susceptibility to artesunate

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions
increases lipidation

3-methyladenine inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; acadesine promotes the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; dorsomorphin inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; Sirolimus promotes the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

microsomal glutathione S-transferase 3

affects response to substance

MGST3 mRNA affects the susceptibility to artesunate

NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411

G

marker of proliferation Ki-67

multiple interactions

artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein]

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

matrix metallopeptidase 9

multiple interactions
decreases expression

artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MMP9 protein]
Chloroquine inhibits the reaction [Artesunate results in decreased expression of MMP9 mRNA]

PMID:29031619 PMID:30551460

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

myeloperoxidase

multiple interactions

artesunate inhibits the reaction [Ethanol results in increased activity of MPO protein]

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

decreases response to substance

MTHFD2 mRNA results in decreased susceptibility to artesunate

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

mechanistic target of rapamycin kinase

multiple interactions
decreases phosphorylation

acadesine promotes the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein]

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

MYD88, innate immune signal transduction adaptor

multiple interactions

artesunate inhibits the reaction [Glucose results in increased expression of MYD88 protein]

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

nascent polypeptide associated complex subunit alpha

decreases response to substance

NACA mRNA results in decreased susceptibility to artesunate

NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992

G

NCK-associated protein 1

increases response to substance

NCKAP1 mRNA results in increased susceptibility to artesunate

NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217

G

nuclear receptor coactivator 4

multiple interactions
decreases expression

Chloroquine inhibits the reaction [Artesunate results in decreased expression of NCOA4 mRNA]
Artesunate results in decreased expression of NCOA4 mRNA; Artesunate results in decreased expression of NCOA4 protein

NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641

G

NFE2 like bZIP transcription factor 2

affects localization

artesunate affects the localization of NFE2L2 protein

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NLR family, pyrin domain containing 3

multiple interactions

artesunate inhibits the reaction [Glucose results in increased expression of NLRP3 protein]

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

poly (ADP-ribose) polymerase 1

increases cleavage
multiple interactions

Artesunate results in increased cleavage of PARP1 protein
3-methyladenine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; acadesine promotes the reaction [Artesunate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; dorsomorphin inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; Sirolimus promotes the reaction [Artesunate results in increased cleavage of PARP1 protein]

PMID:24704559 PMID:33002460

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

proliferating cell nuclear antigen

multiple interactions

artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of PCNA protein]

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

progesterone receptor

multiple interactions

artesunate binds to and results in increased activity of PGR protein

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[Carbon Tetrachloride results in increased susceptibility to Artesunate] which results in increased expression of PTGS2 mRNA; [Carbon Tetrachloride results in increased susceptibility to Artesunate] which results in increased expression of PTGS2 protein

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

artesunate inhibits the reaction [Ethanol results in increased expression of RELA protein]; artesunate inhibits the reaction [Glucose results in increased phosphorylation of RELA protein]

PMID:27474069 PMID:30031708

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

replication protein A2

increases phosphorylation

Artesunate results in increased phosphorylation of RPA2 protein

NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350

G

ribosomal protein L41

decreases response to substance

RPL41 mRNA results in decreased susceptibility to artesunate

NCBI chr 7:977,885...978,965

G

ribosomal protein L6

decreases response to substance

RPL6 mRNA results in decreased susceptibility to artesunate

NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921

G

ribosomal protein L7

decreases response to substance

RPL7 mRNA results in decreased susceptibility to artesunate

NCBI chr 5:3,217,184...3,220,192

G

ribosomal protein S12

decreases response to substance

RPS12 mRNA results in decreased susceptibility to artesunate

NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014

G

ribosomal protein S15a

decreases response to substance

RPS15A mRNA results in decreased susceptibility to artesunate

NCBI chr 1:172,420,151...172,427,021
Ensembl chr 1:172,419,761...172,426,995

G

ribosomal protein S6

decreases response to substance

RPS6 mRNA results in decreased susceptibility to artesunate

NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602

G

solute carrier family 25 member 19

decreases response to substance

SLC25A19 mRNA results in decreased susceptibility to artesunate

NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447

G

Sp1 transcription factor

decreases expression

artesunate results in decreased expression of SP1 protein

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

sequestosome 1

multiple interactions
decreases expression

Chloroquine inhibits the reaction [Artesunate results in decreased expression of SQSTM1 protein]
Artesunate results in decreased expression of SQSTM1 mRNA; Artesunate results in decreased expression of SQSTM1 protein

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

serine and arginine rich splicing factor 2

decreases response to substance

SRSF2 mRNA results in decreased susceptibility to artesunate

NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338

G

TIMP metallopeptidase inhibitor 1

increases expression
multiple interactions

Artesunate results in increased expression of TIMP1 mRNA
Chloroquine inhibits the reaction [Artesunate results in increased expression of TIMP1 mRNA]

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

toll-like receptor 4

multiple interactions

artesunate inhibits the reaction [Glucose results in increased expression of TLR4 protein]

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

tumor necrosis factor

multiple interactions

artesunate inhibits the reaction [Ethanol results in increased expression of TNF protein]; artesunate inhibits the reaction [Glucose results in increased expression of TNF mRNA]; artesunate inhibits the reaction [Glucose results in increased secretion of TNF protein]

PMID:27474069 PMID:30031708

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

tumor protein p53

increases expression
multiple interactions

Artesunate results in increased expression of TP53 protein
Artesunate inhibits the reaction [TPT1 protein binds to TP53 protein]

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein, translationally-controlled 1

affects response to substance
multiple interactions

TPT1 protein affects the susceptibility to artesunate
Artesunate binds to and results in decreased expression of TPT1 protein; Artesunate inhibits the reaction [TPT1 protein binds to TP53 protein]

PMID:15878303 PMID:33259807

NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625

G

Tu translation elongation factor, mitochondrial

decreases response to substance

TUFM mRNA results in decreased susceptibility to artesunate

NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395

G

unc-51 like autophagy activating kinase 1

increases phosphorylation
multiple interactions

Artesunate results in increased phosphorylation of ULK1 protein
acadesine promotes the reaction [Artesunate results in increased phosphorylation of ULK1 protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased phosphorylation of ULK1 protein]; dorsomorphin inhibits the reaction [Artesunate results in increased phosphorylation of ULK1 protein]

NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966

G

vascular endothelial growth factor A

multiple interactions

artesunate inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of VEGFA protein]

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

YY1 transcription factor

decreases expression

artesunate results in decreased expression of YY1 protein

NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747

G

zinc finger and BTB domain containing 4

increases response to substance

ZBTB4 mRNA results in increased susceptibility to artesunate

NCBI chr10:54,480,698...54,501,492
Ensembl chr10:54,485,071...54,501,492

caspofungin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

histamine N-methyltransferase

decreases activity

caspofungin results in decreased activity of HNMT protein

NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012

cefaloridine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase

increases expression

Cephaloridine results in increased expression of AADAC mRNA

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

aminoadipate-semialdehyde synthase

decreases expression

Cephaloridine results in decreased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

ATP-binding cassette, sub-family B member 1B

increases expression

Cephaloridine results in increased expression of ABCB1B mRNA

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily C member 2

increases expression

Cephaloridine results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

aminocarboxymuconate semialdehyde decarboxylase

decreases expression

Cephaloridine results in decreased expression of ACMSD mRNA

NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209

G

acyl-CoA thioesterase 9

increases expression

Cephaloridine results in increased expression of ACOT9 mRNA

NCBI chr X:40,073,197...40,123,573
Ensembl chr X:40,064,810...40,123,559

G

acyl-CoA synthetase medium-chain family member 5

decreases expression

Cephaloridine results in decreased expression of ACSM5 mRNA

NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588

G

ADAM metallopeptidase domain 8

decreases expression

Cephaloridine results in decreased expression of ADAM8 mRNA

NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801

G

adhesion G protein-coupled receptor E1

increases expression

Cephaloridine results in increased expression of ADGRE1 mRNA

NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000

G

adenosine A2a receptor

increases expression

Cephaloridine results in increased expression of ADORA2A mRNA

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

adrenoceptor alpha 1D

increases expression

Cephaloridine results in increased expression of ADRA1D mRNA

NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354

G

aftiphilin

decreases expression

Cephaloridine results in decreased expression of AFTPH mRNA

NCBI chr14:94,871,429...94,925,625
Ensembl chr14:94,871,429...94,925,376

G

aldo-keto reductase family 1 member B1

increases expression

Cephaloridine results in increased expression of AKR1B1 mRNA

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1, member D1

increases expression

Cephaloridine results in increased expression of AKR1D1 mRNA

NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372

G

5'-aminolevulinate synthase 1

increases expression

Cephaloridine results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

aldehyde dehydrogenase 3 family, member A1

increases expression

Cephaloridine results in increased expression of ALDH3A1 mRNA

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

aldehyde dehydrogenase 3 family, member B1

increases expression

Cephaloridine results in increased expression of ALDH3B1 mRNA

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

aldolase, fructose-bisphosphate A

affects expression

Cephaloridine affects the expression of ALDOA mRNA

NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182

G

APC membrane recruitment protein 2

decreases expression

Cephaloridine results in decreased expression of AMER2 mRNA

NCBI chr15:34,525,352...34,535,660
Ensembl chr15:34,524,542...34,528,455

G

adhesion molecule with Ig like domain 2

increases expression

Cephaloridine results in increased expression of AMIGO2 mRNA

NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695

G

adenosine monophosphate deaminase 1

increases expression

Cephaloridine results in increased expression of AMPD1 mRNA

NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938

G

adenosine monophosphate deaminase 3

increases expression

Cephaloridine results in increased expression of AMPD3 mRNA

NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887

G

angiopoietin-like 4

increases expression

Cephaloridine results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

anillin, actin binding protein

decreases expression

Cephaloridine results in decreased expression of ANLN mRNA

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

annexin A13

decreases expression

Cephaloridine results in decreased expression of ANXA13 mRNA

NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907

G

annexin A7

increases expression

Cephaloridine results in increased expression of ANXA7 mRNA

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

G

amyloid P component, serum

decreases expression

Cephaloridine results in decreased expression of APCS mRNA

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

G

apolipoprotein A4

increases expression

Cephaloridine results in increased expression of APOA4 mRNA

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein B

increases expression

Cephaloridine results in increased expression of APOB mRNA

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

apolipoprotein C2

increases expression

Cephaloridine results in increased expression of APOC2 mRNA

NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476

G

apolipoprotein L domain containing 1

decreases expression

Cephaloridine results in decreased expression of APOLD1 mRNA

NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706

G

ARFGEF family member 3

decreases expression

Cephaloridine results in decreased expression of ARFGEF3 mRNA

NCBI chr 1:13,245,578...13,404,319
Ensembl chr 1:13,244,830...13,404,084

G

Rho GTPase activating protein 35

decreases expression

Cephaloridine results in decreased expression of ARHGAP35 mRNA

NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298

G

AT-rich interaction domain 5A

increases expression

Cephaloridine results in increased expression of ARID5A mRNA

NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597

G

anti-silencing function 1B histone chaperone

increases expression

Cephaloridine results in increased expression of ASF1B mRNA

NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549

G

ASH1 like histone lysine methyltransferase

decreases expression

Cephaloridine results in decreased expression of ASH1L mRNA

NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

Cephaloridine results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

ATPase family, AAA domain containing 1

increases expression

Cephaloridine results in increased expression of ATAD1 mRNA

NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548

G

ATPase family, AAA domain containing 2

increases expression

Cephaloridine results in increased expression of ATAD2 mRNA

NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738

G

activating transcription factor 3

decreases expression

Cephaloridine results in decreased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

atlastin GTPase 1

increases expression

Cephaloridine results in increased expression of ATL1 mRNA

NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204

G

ATPase phospholipid transporting 11C

decreases expression

Cephaloridine results in decreased expression of ATP11C mRNA

NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

increases expression

Cephaloridine results in increased expression of ATP12A mRNA

NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229

G

aurora kinase B

decreases expression

Cephaloridine results in decreased expression of AURKB mRNA

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

G

Beta-1,3-galactosyltransferase 2

decreases expression

Cephaloridine results in decreased expression of B3GALT2 mRNA

NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

decreases expression

Cephaloridine results in decreased expression of B3GNT7 mRNA

NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170

G

BAG cochaperone 3

increases expression

Cephaloridine results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BCL2-antagonist/killer 1

increases expression

Cephaloridine results in increased expression of BAK1 mRNA

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

BRCA1 associated RING domain 1

increases expression

Cephaloridine results in increased expression of BARD1 mRNA

NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265

G

basic leucine zipper ATF-like transcription factor

increases expression

Cephaloridine results in increased expression of BATF mRNA

NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051

G

Bcl2-like 1

affects expression

Cephaloridine affects the expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

brain expressed X-linked 2

increases expression

Cephaloridine results in increased expression of BEX1 mRNA

NCBI chr X:99,019,847...99,021,375
Ensembl chr X:99,019,000...99,021,503

G

brain expressed, X-linked 4

increases expression

Cephaloridine results in increased expression of BEX4 mRNA

NCBI chr X:99,131,985...99,133,417
Ensembl chr X:99,131,942...99,133,531

G

basic helix-loop-helix family, member e41

increases expression

Cephaloridine results in increased expression of BHLHE41 mRNA

NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468

G

baculoviral IAP repeat-containing 3

increases expression

Cephaloridine results in increased expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

biliverdin reductase B

increases expression

Cephaloridine results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

bactericidal/permeability-increasing protein

increases expression

Cephaloridine results in increased expression of BPI mRNA

NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221

G

BRCA1 interacting DNA helicase 1

increases expression

Cephaloridine results in increased expression of BRIP1 mRNA

NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324

G

barttin CLCNK type accessory subunit beta

increases expression

Cephaloridine results in increased expression of BSND mRNA

NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:121,251,774...121,260,571

G

BTG anti-proliferation factor 2

decreases expression

Cephaloridine results in decreased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

BUB1 mitotic checkpoint serine/threonine kinase B

decreases expression

Cephaloridine results in decreased expression of BUB1B mRNA

NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547

G

similar to human chromosome 16 open reading frame 89

increases expression

Cephaloridine results in increased expression of C10H16ORF89 mRNA

NCBI chr10:10,361,909...10,371,046
Ensembl chr10:10,361,948...10,371,046

G

C1q and TNF related 1

increases expression

Cephaloridine results in increased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

G

complement C5

decreases expression

Cephaloridine results in decreased expression of C5 mRNA

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

complement C6

increases expression

Cephaloridine results in increased expression of C6 mRNA

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

G

calcium voltage-gated channel subunit alpha1 H

increases expression

Cephaloridine results in increased expression of CACNA1H mRNA

NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376

G

calcium voltage-gated channel auxiliary subunit gamma 3

increases expression

Cephaloridine results in increased expression of CACNG3 mRNA

NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024

G

calbindin 1

increases expression

Cephaloridine results in increased expression of CALB1 mRNA

NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431

G

calbindin 2

decreases expression

Cephaloridine results in decreased expression of CALB2 mRNA

NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438

G

calreticulin

increases expression

Cephaloridine results in increased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

CaM kinase-like vesicle-associated

increases expression

Cephaloridine results in increased expression of CAMKV mRNA

NCBI chr 8:108,626,821...108,641,169
Ensembl chr 8:108,626,821...108,641,169

G

calnexin

increases expression

Cephaloridine results in increased expression of CANX mRNA

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

catalase

affects expression

Cephaloridine affects the expression of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

coiled-coil domain containing 113

increases expression

Cephaloridine results in increased expression of CCDC113 mRNA

NCBI chr19:9,497,000...9,516,917
Ensembl chr19:9,496,886...9,516,923

G

C-C motif chemokine ligand 17

increases expression

Cephaloridine results in increased expression of CCL17 mRNA

NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819

G

C-C motif chemokine ligand 19

increases expression

Cephaloridine results in increased expression of CCL19 mRNA

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

G

C-C motif chemokine ligand 20

increases expression

Cephaloridine results in increased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 28

increases expression

Cephaloridine results in increased expression of CCL28 mRNA

NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997

G

C-C motif chemokine ligand 3

decreases expression

Cephaloridine results in decreased expression of CCL3 mRNA

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 4

decreases expression

Cephaloridine results in decreased expression of CCL4 mRNA

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

cellular communication network factor 2

decreases expression

Cephaloridine results in decreased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin A2

decreases expression

Cephaloridine results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression

Cephaloridine results in decreased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

decreases expression

Cephaloridine results in decreased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin E1

increases expression

Cephaloridine results in increased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

increases expression

Cephaloridine results in increased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

CD52 molecule

decreases expression

Cephaloridine results in decreased expression of CD52 mRNA

NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348

G

Cd72 molecule

increases expression

Cephaloridine results in increased expression of CD72 mRNA

NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725

G

CD86 molecule

increases expression

Cephaloridine results in increased expression of CD86 mRNA

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

cell division cycle 42

decreases expression

Cephaloridine results in decreased expression of CDC42 mRNA

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

G

cell division cycle 45

increases expression

Cephaloridine results in increased expression of CDC45 mRNA

NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619

G

cell division cycle 6

increases expression

Cephaloridine results in increased expression of CDC6 mRNA

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cell division cycle associated 2

decreases expression

Cephaloridine results in decreased expression of CDCA2 mRNA

NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611

G

cyclin-dependent kinase 1

decreases expression

Cephaloridine results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin dependent kinase like 1

decreases expression

Cephaloridine results in decreased expression of CDKL1 mRNA

NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276

G

cyclin-dependent kinase inhibitor 1A

decreases expression

Cephaloridine results in decreased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

decreases expression

Cephaloridine results in decreased expression of CDKN1B mRNA

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

chromatin licensing and DNA replication factor 1

increases expression

Cephaloridine results in increased expression of CDT1 mRNA

NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659

G

CEA cell adhesion molecule 16, tectorial membrane component

increases expression

Cephaloridine results in increased expression of CEACAM16 mRNA

NCBI chr 1:79,514,975...79,524,871
Ensembl chr 1:79,514,975...79,524,871

G

centromere protein K

increases expression

Cephaloridine results in increased expression of CENPK mRNA

NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706

G

centromere protein Q

increases expression

Cephaloridine results in increased expression of CENPQ mRNA

NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789

G

carboxylesterase-like 1

decreases expression

Cephaloridine results in decreased expression of CESL1 mRNA

NCBI chr19:22,670,709...23,006,329
Ensembl chr19:22,670,712...22,712,608

G

chromatin assembly factor 1 subunit A

increases expression

Cephaloridine results in increased expression of CHAF1A mRNA

NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654

G

chromatin assembly factor 1 subunit B

increases expression

Cephaloridine results in increased expression of CHAF1B mRNA

NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070

G

chromodomain helicase DNA binding protein 4

decreases expression

Cephaloridine results in decreased expression of CHD4 mRNA

NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541

G

chromodomain helicase DNA binding protein 6

decreases expression

Cephaloridine results in decreased expression of CHD6 mRNA

NCBI chr 3:149,596,509...149,757,765
Ensembl chr 3:149,596,509...149,757,755

G

checkpoint kinase 1

increases expression

Cephaloridine results in increased expression of CHEK1 mRNA

NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009

G

carbohydrate sulfotransferase 7

decreases expression

Cephaloridine results in decreased expression of CHST7 mRNA

NCBI chr X:2,396,260...2,432,828
Ensembl chr X:2,393,874...2,432,840

G

chromosome transmission fidelity factor 18

increases expression

Cephaloridine results in increased expression of CHTF18 mRNA

NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050

G

cartilage intermediate layer protein

decreases expression

Cephaloridine results in decreased expression of CILP mRNA

NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

increases expression

Cephaloridine results in increased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

cytoskeleton associated protein 2

decreases expression

Cephaloridine results in decreased expression of CKAP2 mRNA

NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913

G

claudin 14

increases expression

Cephaloridine results in increased expression of CLDN14 mRNA

NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171

G

calsyntenin 2

decreases expression

Cephaloridine results in decreased expression of CLSTN2 mRNA

NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731

G

c-Maf-inducing protein

decreases expression

Cephaloridine results in decreased expression of CMIP mRNA

NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709

G

carnosine dipeptidase 1

decreases expression

Cephaloridine results in decreased expression of CNDP1 mRNA

NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765

G

collagen type IV alpha 4 chain

decreases expression

Cephaloridine results in decreased expression of COL4A4 mRNA

NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876

G

collagen type VII alpha 1 chain

increases expression

Cephaloridine results in increased expression of COL7A1 mRNA

NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252

G

carnitine palmitoyltransferase 1B

increases expression

Cephaloridine results in increased expression of CPT1B mRNA

NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404

G

cellular retinoic acid binding protein 1

increases expression

Cephaloridine results in increased expression of CRABP1 mRNA

NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360

G

CREB binding protein

decreases expression

Cephaloridine results in decreased expression of CREBBP mRNA

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

cryptochrome circadian regulator 1

increases expression

Cephaloridine results in increased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

C-X-C motif chemokine ligand 1

decreases expression

Cephaloridine results in decreased expression of CXCL1 mRNA

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 10

increases expression

Cephaloridine results in increased expression of CXCL10 mRNA

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 13

increases expression

Cephaloridine results in increased expression of CXCL13 mRNA

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 14

increases expression

Cephaloridine results in increased expression of CXCL14 mRNA

NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839

G

CXXC finger protein 4

decreases expression

Cephaloridine results in decreased expression of CXXC4 mRNA

NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365

G

cytochrome b5 type A

increases expression

Cephaloridine results in increased expression of CYB5A mRNA

NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

Cephaloridine results in increased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 24, subfamily a, polypeptide 1

decreases expression

Cephaloridine results in decreased expression of CYP24A1 mRNA

NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383

G

cytochrome P450, subfamily 2, polypeptide 11

decreases expression

Cephaloridine results in decreased expression of CYP2C mRNA

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450 family 7 subfamily B member 1

increases expression

Cephaloridine results in increased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

dCTP pyrophosphatase 1

increases expression

Cephaloridine results in increased expression of DCTPP1 mRNA

NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839

G

dCTP pyrophosphatase 1, pseudogene 2

increases expression

Cephaloridine results in increased expression of DCTPP1-PS2 mRNA

NCBI chr16:1,392,967...1,393,868

G

dopa decarboxylase

decreases expression

Cephaloridine results in decreased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage-inducible transcript 4

decreases expression

Cephaloridine results in decreased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DNA-damage-inducible transcript 4-like

increases expression

Cephaloridine results in increased expression of DDIT4L mRNA

NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375

G

DExD-box helicase 39A

increases expression

Cephaloridine results in increased expression of DDX39A mRNA

NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954

G

DEAD-box helicase 6

decreases expression

Cephaloridine results in decreased expression of DDX6 mRNA

NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405
Ensembl chr 8:44,931,974...44,964,405

G

2,4-dienoyl-CoA reductase 2

decreases expression

Cephaloridine results in decreased expression of DECR2 mRNA

NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479

G

dehydrogenase/reductase member 2 like 1

increases expression

Cephaloridine results in increased expression of DHRS2L1 mRNA

NCBI chr15:28,635,197...28,638,087
Ensembl chr15:28,635,197...28,638,087

G

DLG associated protein 1

increases expression

Cephaloridine results in increased expression of DLGAP1 mRNA

NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817

G

dynein, axonemal, heavy chain 7

decreases expression

Cephaloridine results in decreased expression of DNAH7 mRNA

NCBI chr 9:54,960,235...55,266,529
Ensembl chr 9:54,960,440...55,262,297

G

dynein, axonemal, heavy chain 9

decreases expression

Cephaloridine results in decreased expression of DNAH9 mRNA

NCBI chr10:50,496,174...50,864,909
Ensembl chr10:50,497,688...50,864,949

G

deoxyribonuclease 1L3

increases expression

Cephaloridine results in increased expression of DNASE1L3 mRNA

NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

increases expression

Cephaloridine results in increased expression of DNPH1 mRNA

NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022

G

DNA replication fork stabilization factor DONSON

increases expression

Cephaloridine results in increased expression of DONSON mRNA

NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889

G

double PHD fingers 1

increases expression

Cephaloridine results in increased expression of DPF1 mRNA

NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950

G

DNA replication and sister chromatid cohesion 1

increases expression

Cephaloridine results in increased expression of DSCC1 mRNA

NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212

G

desmoglein 2

increases expression

Cephaloridine results in increased expression of DSG2 mRNA

NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156

G

deltex E3 ubiquitin ligase 4

increases expression

Cephaloridine results in increased expression of DTX4 mRNA

NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818

G

dual specificity phosphatase 6

affects expression

Cephaloridine affects the expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 7

decreases expression

Cephaloridine results in decreased expression of DUSP7 mRNA

NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404

G

dual specificity phosphatase 9

increases expression

Cephaloridine results in increased expression of DUSP9 mRNA

NCBI chr X:151,351,897...151,355,822
Ensembl chr X:151,351,897...151,355,821

G

E2F transcription factor 8

increases expression

Cephaloridine results in increased expression of E2F8 mRNA

NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098

G

erythroid differentiation regulatory factor 1

decreases expression

Cephaloridine results in decreased expression of EDRF1 mRNA

NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701

G

eukaryotic translation elongation factor 2

increases expression

Cephaloridine results in increased expression of EEF2 mRNA

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

early growth response 1

decreases expression

Cephaloridine results in decreased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 2

decreases expression

Cephaloridine results in decreased expression of EGR2 mRNA

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

eukaryotic translation initiation factor 4H

increases expression

Cephaloridine results in increased expression of EIF4H mRNA

NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876

G

E74 like ETS transcription factor 3

increases expression

Cephaloridine results in increased expression of ELF3 mRNA

NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481

G

embigin

increases expression

Cephaloridine results in increased expression of EMB mRNA

NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050

G

essential meiotic structure-specific endonuclease 1

decreases expression

Cephaloridine results in decreased expression of EME1 mRNA

NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435

G

ectodermal-neural cortex 1

increases expression

Cephaloridine results in increased expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

enolase 2

increases expression

Cephaloridine results in increased expression of ENO2 mRNA

NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980

G

endosomal transmembrane epsin interactor 1

increases expression

Cephaloridine results in increased expression of ENTREP1 mRNA

NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758

G

extra spindle pole bodies like 1, separase

decreases expression

Cephaloridine results in decreased expression of ESPL1 mRNA

NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984

G

exonuclease 1

increases expression

Cephaloridine results in increased expression of EXO1 mRNA

NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654

G

coagulation factor XIII B chain

decreases expression

Cephaloridine results in decreased expression of F13B mRNA

NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381

G

FAM111 trypsin like peptidase A

decreases expression

Cephaloridine results in decreased expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

FA complementation group D2

increases expression

Cephaloridine results in increased expression of FANCD2 mRNA

NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412

G

fibulin 1

increases expression

Cephaloridine results in increased expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

fructose-bisphosphatase 2

increases expression

Cephaloridine results in increased expression of FBP2 mRNA

NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698

G

F-box protein 5

increases expression

Cephaloridine results in increased expression of FBXO5 mRNA

NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437

G

Fc gamma receptor 2A

increases expression

Cephaloridine results in increased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

Fc gamma receptor 2B

increases expression

Cephaloridine results in increased expression of FCGR2B mRNA

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

G

Fc gamma receptor 3A

increases expression

Cephaloridine results in increased expression of FCGR3A mRNA

NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921

G

ficolin B

increases expression

Cephaloridine results in increased expression of FCNB mRNA

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

G

flap structure-specific endonuclease 1

increases expression

Cephaloridine results in increased expression of FEN1 mRNA

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

fibrinogen beta chain

increases expression

Cephaloridine results in increased expression of FGB mRNA

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

fibroblast growth factor 17

increases expression

Cephaloridine results in increased expression of FGF17 mRNA

NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063

G

fibrinogen-like 2

increases expression

Cephaloridine results in increased expression of FGL2 mRNA

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

FH2 domain containing 1

increases expression

Cephaloridine results in increased expression of FHDC1 mRNA

NCBI chr 2:169,790,917...169,829,580
Ensembl chr 2:169,790,947...169,827,896

G

filamin A interacting protein 1

decreases expression

Cephaloridine results in decreased expression of FILIP1 mRNA

NCBI chr 8:80,761,283...80,956,556
Ensembl chr 8:80,764,604...80,922,549

G

folate hydrolase 1

decreases expression

Cephaloridine results in decreased expression of FOLH1 mRNA

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression

Cephaloridine results in decreased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box E1

decreases expression

Cephaloridine results in decreased expression of FOXE1 mRNA

NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835

G

forkhead box Q1

increases expression

Cephaloridine results in increased expression of FOXQ1 mRNA

NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377

G

FYVE and coiled-coil domain autophagy adaptor 1

decreases expression

Cephaloridine results in decreased expression of FYCO1 mRNA

NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

Cephaloridine results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

glucose-6-phosphate dehydrogenase

increases expression

Cephaloridine results in increased expression of G6PD mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

growth arrest and DNA-damage-inducible, alpha

increases expression

Cephaloridine results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 13

increases expression

Cephaloridine results in increased expression of GALNT13 mRNA

NCBI chr 3:38,903,695...39,560,683
Ensembl chr 3:38,974,490...39,558,803

G

glucosidase, alpha; neutral C

decreases expression

Cephaloridine results in decreased expression of GANC mRNA

NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241

G

golgi associated RAB2 interactor family member 4

increases expression

Cephaloridine results in increased expression of GARIN4 mRNA

NCBI chr13:102,742,988...102,745,168
Ensembl chr13:102,742,988...102,745,168

G

glucosylceramidase beta 3

decreases expression

Cephaloridine results in decreased expression of GBA3 mRNA

NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653

G

guanine deaminase

increases expression

Cephaloridine results in increased expression of GDA mRNA

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

growth differentiation factor 15

decreases expression

Cephaloridine results in decreased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

GDNF family receptor alpha 2

decreases expression

Cephaloridine results in decreased expression of GFRA2 mRNA

NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714

G

GINS complex subunit 2

increases expression

Cephaloridine results in increased expression of GINS2 mRNA

NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339

G

GINS complex subunit 4

increases expression

Cephaloridine results in increased expression of GINS4 mRNA

NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273

G

geminin, DNA replication inhibitor

increases expression

Cephaloridine results in increased expression of GMNN mRNA

NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054

G

G protein subunit alpha 14

increases expression

Cephaloridine results in increased expression of GNA14 mRNA

NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423

G

glycoprotein nmb

increases expression

Cephaloridine results in increased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

G protein-coupled receptor 135

decreases expression

Cephaloridine results in decreased expression of GPR135 mRNA

NCBI chr 6:90,627,533...90,630,661
Ensembl chr 6:90,629,178...90,630,551

G

G protein-coupled receptor 19

increases expression

Cephaloridine results in increased expression of GPR19 mRNA

NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036

G

glutathione peroxidase 2

increases expression

Cephaloridine results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutamate ionotropic receptor AMPA type subunit 3

decreases expression

Cephaloridine results in decreased expression of GRIA3 mRNA

NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096

G

glutathione-disulfide reductase

increases expression

Cephaloridine results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 2

increases expression

Cephaloridine results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 5

increases expression

Cephaloridine results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

increases expression

Cephaloridine results in increased expression of GSTM1 mRNA

PMID:18172885 PMID:18500788

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase pi 1

increases expression

Cephaloridine results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glucoside xylosyltransferase 1

decreases expression

Cephaloridine results in decreased expression of GXYLT1 mRNA

NCBI chr 7:124,400,896...124,434,682
Ensembl chr 7:124,400,896...124,434,699

G

H1.1 linker histone, cluster member

increases expression

Cephaloridine results in increased expression of H1F1 mRNA

NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011

G

hydroxyacyl-CoA dehydrogenase

decreases expression

Cephaloridine results in decreased expression of HADH mRNA

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

G

HAUS augmin-like complex, subunit 8

increases expression

Cephaloridine results in increased expression of HAUS8 mRNA

NCBI chr16:17,930,819...17,945,254
Ensembl chr16:17,930,820...17,945,237

G

hepatitis A virus cellular receptor 1

increases expression

Cephaloridine results in increased expression of HAVCR1 mRNA

PMID:18500788 PMID:20305092

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

HCK proto-oncogene, Src family tyrosine kinase

increases expression

Cephaloridine results in increased expression of HCK mRNA

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

G

heme binding protein 1

increases expression

Cephaloridine results in increased expression of HEBP1 mRNA

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

heme binding protein 2

increases expression

Cephaloridine results in increased expression of HEBP2 mRNA

NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777

G

helicase, lymphoid specific

increases expression

Cephaloridine results in increased expression of HELLS mRNA

NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844

G

HEPACAM family member 2

increases expression

Cephaloridine results in increased expression of HEPACAM2 mRNA

NCBI chr 4:31,446,195...31,480,859
Ensembl chr 4:31,446,169...31,480,953

G

hemojuvelin BMP co-receptor

decreases expression

Cephaloridine results in decreased expression of HJV mRNA

NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850

G

H2.0-like homeobox

decreases expression

Cephaloridine results in decreased expression of HLX mRNA

NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

Cephaloridine results in decreased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression

Cephaloridine results in increased expression of HMOX1 mRNA

PMID:18172885 PMID:18500788

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

H6 family homeobox 3

increases expression

Cephaloridine results in increased expression of HMX3 mRNA

NCBI chr 1:186,313,237...186,315,201
Ensembl chr 1:186,313,063...186,315,201

G

heterogeneous nuclear ribonucleoprotein A1

increases expression

Cephaloridine results in increased expression of HNRNPA1 mRNA

NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609

G

heterogeneous nuclear ribonucleoprotein A1, pseudogene 28

increases expression

Cephaloridine results in increased expression of HNRNPA1-PS28 mRNA

NCBI chr X:107,752,105...107,759,183

G

histidine-rich glycoprotein

decreases expression

Cephaloridine results in decreased expression of HRG mRNA

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

G

hydroxysteroid (17-beta) dehydrogenase 2

decreases expression

Cephaloridine results in decreased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

increases expression

Cephaloridine results in increased expression of HSD3B1 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

heat shock protein 90 alpha family class A member 1

increases expression

Cephaloridine results in increased expression of HSP90AA1 mRNA

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein family A (Hsp70) member 1A

increases expression

Cephaloridine results in increased expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

Cephaloridine results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family H (Hsp110) member 1

increases expression

Cephaloridine results in increased expression of HSPH1 mRNA

NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224

G

HIV-1 Tat interactive protein 2

increases expression

Cephaloridine results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

5-hydroxytryptamine (serotonin) receptor 5B

increases expression

Cephaloridine results in increased expression of HTR5B mRNA

NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835

G

intercellular adhesion molecule 1

increases expression

Cephaloridine results in increased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

isopentenyl-diphosphate delta isomerase 2 like 3

decreases expression

Cephaloridine results in decreased expression of IDI2L3 mRNA

NCBI chr17:61,518,138...61,535,484
Ensembl chr17:61,519,390...61,531,603

G

immediate early response 3

decreases expression

Cephaloridine results in decreased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon induced transmembrane protein 10

increases expression

Cephaloridine results in increased expression of IFITM10 mRNA

NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151

G

interleukin 18

increases expression

Cephaloridine results in increased expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

decreases expression

Cephaloridine results in decreased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 20 receptor subunit alpha

decreases expression

Cephaloridine results in decreased expression of IL20RA mRNA

NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602

G

inhibin subunit beta B

decreases expression

Cephaloridine results in decreased expression of INHBB mRNA

NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832

G

inositol-trisphosphate 3-kinase A

increases expression

Cephaloridine results in increased expression of ITPKA mRNA

NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600

G

inositol-trisphosphate 3-kinase B

increases expression

Cephaloridine results in increased expression of ITPKB mRNA

NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004

G

jade family PHD finger 2

decreases expression

Cephaloridine results in decreased expression of JADE2 mRNA

NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

Cephaloridine results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

decreases expression
increases expression

Cephaloridine results in decreased expression of JUNB mRNA
Cephaloridine results in increased expression of JUNB mRNA

PMID:18172885 PMID:18500788

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

kelch repeat and BTB domain containing 11

decreases expression

Cephaloridine results in decreased expression of KBTBD11 mRNA

NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736

G

potassium voltage-gated channel subfamily H member 1

increases expression

Cephaloridine results in increased expression of KCNH1 mRNA

NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740

G

potassium inwardly-rectifying channel, subfamily J, member 15

decreases expression

Cephaloridine results in decreased expression of KCNJ15 mRNA

NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952

G

potassium channel tetramerization domain containing 1

increases expression

Cephaloridine results in increased expression of KCTD1 mRNA

NCBI chr18:6,122,390...6,316,434
Ensembl chr18:6,122,390...6,317,393

G

alpha-ketoglutarate dehydrogenase subunit 4

increases expression

Cephaloridine results in increased expression of KGD4 mRNA

NCBI chr 2:31,870,549...31,878,335
Ensembl chr 2:31,870,551...31,880,730

G

kinesin family member 18A

decreases expression

Cephaloridine results in decreased expression of KIF18A mRNA

NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582

G

kinesin family member 2C

decreases expression

Cephaloridine results in decreased expression of KIF2C mRNA

NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637

G

KLF transcription factor 7

decreases expression

Cephaloridine results in decreased expression of KLF7 mRNA

NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261

G

kelch-like family member 25

decreases expression

Cephaloridine results in decreased expression of KLHL25 mRNA

NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227

G

kinetochore-localized astrin/SPAG5 binding protein

decreases expression

Cephaloridine results in decreased expression of KNSTRN mRNA

NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715

G

kinetochore associated 1

increases expression

Cephaloridine results in increased expression of KNTC1 mRNA

NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561

G

laminin subunit alpha 2

decreases expression

Cephaloridine results in decreased expression of LAMA2 mRNA

NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530

G

laminin subunit beta 3

increases expression

Cephaloridine results in increased expression of LAMB3 mRNA

NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405

G

leucyl-tRNA synthetase 1

decreases expression

Cephaloridine results in decreased expression of LARS1 mRNA

NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931

G

ligand dependent nuclear receptor corepressor

decreases expression

Cephaloridine results in decreased expression of LCOR mRNA

NCBI chr 1:240,298,565...240,405,627
Ensembl chr 1:240,298,563...240,402,448

G

leukocyte cell-derived chemotaxin 2

decreases expression

Cephaloridine results in decreased expression of LECT2 mRNA

NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983

G

galectin 2

increases expression

Cephaloridine results in increased expression of LGALS2 mRNA

NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802

G

galectin 3

increases expression

Cephaloridine results in increased expression of LGALS3 mRNA

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

LIM homeobox 3

decreases expression

Cephaloridine results in decreased expression of LHX3 mRNA

NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480

G

DNA ligase 1

increases expression

Cephaloridine results in increased expression of LIG1 mRNA

NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413

G

lamin B1

decreases expression

Cephaloridine results in decreased expression of LMNB1 mRNA

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

LRAT domain containing 1

increases expression

Cephaloridine results in increased expression of LRATD1 mRNA

NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319

G

leucine rich repeat neuronal 3

decreases expression

Cephaloridine results in decreased expression of LRRN3 mRNA

NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330

G

MAF bZIP transcription factor

decreases expression

Cephaloridine results in decreased expression of MAF mRNA

NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365

G

mitogen-activated protein kinase kinase kinase 1

increases expression

Cephaloridine results in increased expression of MAP3K1 mRNA

NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463

G

mitogen activated protein kinase kinase kinase 12

decreases expression

Cephaloridine results in decreased expression of MAP3K12 mRNA

NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation
increases activity

Thymic Factor, Circulating inhibits the reaction [Cephaloridine results in increased phosphorylation of MAPK1 protein]
Cephaloridine results in increased activity of MAPK1 protein

PMID:16154539 PMID:16272694

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases activity
multiple interactions
increases phosphorylation

Cephaloridine results in increased activity of MAPK3 protein
Thymic Factor, Circulating inhibits the reaction [Cephaloridine results in increased phosphorylation of MAPK3 protein]

PMID:16154539 PMID:16272694

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8 interacting protein 3

increases expression

Cephaloridine results in increased expression of MAPK8IP3 mRNA

NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273

G

MBL associated serine protease 2

increases expression

Cephaloridine results in increased expression of MASP2 mRNA

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

G

minichromosome maintenance complex component 2

increases expression

Cephaloridine results in increased expression of MCM2 mRNA

NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847

G

minichromosome maintenance complex component 3

increases expression

Cephaloridine results in increased expression of MCM3 mRNA

NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314

G

minichromosome maintenance complex component 5

increases expression

Cephaloridine results in increased expression of MCM5 mRNA

NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389

G

minichromosome maintenance complex component 6

increases expression

Cephaloridine results in increased expression of MCM6 mRNA

NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960

G

minichromosome maintenance complex component 7

increases expression

Cephaloridine results in increased expression of MCM7 mRNA

NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063

G

minichromosome maintenance 8 homologous recombination repair factor

increases expression

Cephaloridine results in increased expression of MCM8 mRNA

NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008

G

mesoderm posterior bHLH transcription factor 1

decreases expression

Cephaloridine results in decreased expression of MESP1 mRNA

NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875

G

MET proto-oncogene, receptor tyrosine kinase

increases expression

Cephaloridine results in increased expression of MET mRNA

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

monoglyceride lipase

decreases expression

Cephaloridine results in decreased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

marker of proliferation Ki-67

decreases expression

Cephaloridine results in decreased expression of MKI67 mRNA

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

matrix metallopeptidase 12

increases expression

Cephaloridine results in increased expression of MMP12 mRNA

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

G

matrix metallopeptidase 16

increases expression

Cephaloridine results in increased expression of MMP16 mRNA

NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388

G

meiotic nuclear divisions 1

increases expression

Cephaloridine results in increased expression of MND1 mRNA

NCBI chr 2:169,433,523...169,496,081
Ensembl chr 2:169,433,540...169,496,096

G

meiosis-specific nuclear structural 1

decreases expression

Cephaloridine results in decreased expression of MNS1 mRNA

NCBI chr 8:73,148,877...73,169,570
Ensembl chr 8:73,148,877...73,176,925

G

mercaptopyruvate sulfurtransferase

decreases expression

Cephaloridine results in decreased expression of MPST mRNA

NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141

G

MPV17 mitochondrial inner membrane protein like

decreases expression

Cephaloridine results in decreased expression of MPV17L mRNA

NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649

G

metallothionein 1

decreases expression

Cephaloridine results in decreased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

increases expression

Cephaloridine results in increased expression of MTHFD1L mRNA

NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

increases expression

Cephaloridine results in increased expression of MTHFD2 mRNA

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

myomesin 3

increases expression

Cephaloridine results in increased expression of MYOM3 mRNA

NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274

G

nuclear receptor co-repressor 2

decreases expression

Cephaloridine results in decreased expression of NCOR2 mRNA

NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319

G

NIMA-related kinase 6

increases expression

Cephaloridine results in increased expression of NEK6 mRNA

NCBI chr 3:22,284,269...22,356,302
Ensembl chr 3:22,284,279...22,395,990

G

nuclear factor, interleukin 3 regulated

increases expression

Cephaloridine results in increased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NFKB inhibitor alpha

decreases expression

Cephaloridine results in decreased expression of NFKBIA mRNA

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor zeta

decreases expression

Cephaloridine results in decreased expression of NFKBIZ mRNA

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

G

nerve growth factor receptor

increases expression

Cephaloridine results in increased expression of NGFR mRNA

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

NHP2 ribonucleoprotein

increases expression

Cephaloridine results in increased expression of NHP2 mRNA

NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545

G

ninjurin 2

increases expression

Cephaloridine results in increased expression of NINJ2 mRNA

NCBI chr 4:153,306,439...153,408,618
Ensembl chr 4:153,306,553...153,408,617

G

nipsnap homolog 3A (C. elegans)

increases expression

Cephaloridine results in increased expression of NIPSNAP3B mRNA

NCBI chr 5:67,613,993...67,625,067
Ensembl chr 5:67,614,036...67,669,700

G

NME/NM23 nucleoside diphosphate kinase 4

decreases expression

Cephaloridine results in decreased expression of NME4 mRNA

NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479

G

NOP56 ribonucleoprotein

increases expression

Cephaloridine results in increased expression of NOP56 mRNA

NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841

G

NAD(P)H quinone dehydrogenase 1

increases expression

Cephaloridine results in increased expression of NQO1 mRNA

PMID:18172885 PMID:18500788

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group D, member 1

increases expression

Cephaloridine results in increased expression of NR1D1 mRNA

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

G

nurim

increases expression

Cephaloridine results in increased expression of NRM mRNA

NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802

G

nudix hydrolase 11

increases expression

Cephaloridine results in increased expression of NUDT10 mRNA; Cephaloridine results in increased expression of NUDT11 mRNA

NCBI chr X:16,326,775...16,333,396
Ensembl chr X:16,326,598...16,333,145

G

opioid related nociceptin receptor 1

increases expression

Cephaloridine results in increased expression of OPRL1 mRNA

NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920

G

olfactory receptor family 2 subfamily W member 6

increases expression

Cephaloridine results in increased expression of OR2W6 mRNA

NCBI chr17:42,906,458...42,907,396
Ensembl chr17:42,904,951...42,919,599

G

olfactory receptor family 52 subfamily B member 2

increases expression

Cephaloridine results in increased expression of OR52B2 mRNA

NCBI chr 1:159,695,507...159,696,475
Ensembl chr 1:159,694,964...159,701,227

G

olfactory receptor family 52 subfamily K member 1

decreases expression

Cephaloridine results in decreased expression of OR52K1 mRNA

NCBI chr 1:157,037,381...157,038,325
Ensembl chr 1:157,037,381...157,038,325

G

origin recognition complex, subunit 6

increases expression

Cephaloridine results in increased expression of ORC6 mRNA

NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662

G

oxysterol binding protein-like 8

decreases expression

Cephaloridine results in decreased expression of OSBPL8 mRNA

NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888

G

oncostatin M receptor

increases expression

Cephaloridine results in increased expression of OSMR mRNA

NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262

G

oxoglutarate receptor 1

increases expression

Cephaloridine results in increased expression of OXGR1 mRNA

NCBI chr15:97,145,947...97,146,960
Ensembl chr15:97,144,293...97,166,612

G

peptidyl arginine deiminase 6

increases expression

Cephaloridine results in increased expression of PADI6 mRNA

NCBI chr 5:153,021,855...153,037,443
Ensembl chr 5:153,021,965...153,037,414

G

partner and localizer of BRCA2

increases expression

Cephaloridine results in increased expression of PALB2 mRNA

NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990

G

PAS domain containing serine/threonine kinase

increases expression

Cephaloridine results in increased expression of PASK mRNA

NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111

G

PDZ binding kinase

decreases expression

Cephaloridine results in decreased expression of PBK mRNA

NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014

G

protocadherin 7

decreases expression

Cephaloridine results in decreased expression of PCDH7 mRNA

NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051

G

protocadherin 9

decreases expression

Cephaloridine results in decreased expression of PCDH9 mRNA

NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538

G

phosphoenolpyruvate carboxykinase 1

decreases expression

Cephaloridine results in decreased expression of PCK1 mRNA

NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191

G

PCNA clamp associated factor

increases expression

Cephaloridine results in increased expression of PCLAF mRNA

NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994

G

proliferating cell nuclear antigen

increases expression

Cephaloridine results in increased expression of PCNA mRNA

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

protein disulfide isomerase family A, member 4

increases expression

Cephaloridine results in increased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

profilin 3

decreases expression

Cephaloridine results in decreased expression of PFN3 mRNA

NCBI chr17:9,217,595...9,218,122

G

pipecolic acid and sarcosine oxidase

increases expression

Cephaloridine results in increased expression of PIPOX mRNA

NCBI chr10:62,769,874...62,783,484
Ensembl chr10:62,769,900...62,782,370

G

pirin

increases expression

Cephaloridine results in increased expression of PIR mRNA

NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218

G

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

decreases expression

Cephaloridine results in decreased expression of PKHD1 mRNA

NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381

G

protein kinase, membrane associated tyrosine/threonine 1

increases expression

Cephaloridine results in increased expression of PKMYT1 mRNA

NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995

G

phospholipase A1 member A

increases expression

Cephaloridine results in increased expression of PLA1A mRNA

NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779

G

pleckstrin 2

increases expression

Cephaloridine results in increased expression of PLEK2 mRNA

NCBI chr 6:97,700,123...97,719,417
Ensembl chr 6:97,701,106...97,719,326

G

pleckstrin homology domain containing A5

decreases expression

Cephaloridine results in decreased expression of PLEKHA5 mRNA

NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546

G

polo-like kinase 1

decreases expression

Cephaloridine results in decreased expression of PLK1 mRNA

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

G

DNA polymerase alpha 2, accessory subunit

increases expression

Cephaloridine results in increased expression of POLA2 mRNA

NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348

G

DNA polymerase delta 1, catalytic subunit

increases expression

Cephaloridine results in increased expression of POLD1 mRNA

NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465

G

DNA polymerase epsilon, catalytic subunit

increases expression

Cephaloridine results in increased expression of POLE mRNA

NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939

G

inorganic pyrophosphatase 1

increases expression

Cephaloridine results in increased expression of PPA1 mRNA

NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215

G

protein phosphatase, Mg2+/Mn2+ dependent, 1J

increases expression

Cephaloridine results in increased expression of PPM1J mRNA

NCBI chr 2:192,278,597...192,283,883
Ensembl chr 2:192,278,517...192,283,882

G

protein phosphatase 1, regulatory subunit 15A

decreases expression

Cephaloridine results in decreased expression of PPP1R15A mRNA

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

protein regulator of cytokinesis 1

decreases expression

Cephaloridine results in decreased expression of PRC1 mRNA

NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765

G

DNA primase subunit 1

increases expression

Cephaloridine results in increased expression of PRIM1 mRNA

NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526

G

protein kinase cAMP-dependent type I regulatory subunit beta

increases expression

Cephaloridine results in increased expression of PRKAR1B mRNA

NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942

G

proline dehydrogenase 2

decreases expression

Cephaloridine results in decreased expression of PRODH2 mRNA

NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:85,753,644...85,767,162

G

paired related homeobox 1

decreases expression

Cephaloridine results in decreased expression of PRRX1 mRNA

NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866

G

serine protease 35

decreases expression

Cephaloridine results in decreased expression of PRSS35 mRNA

NCBI chr 8:87,714,449...87,731,009
Ensembl chr 8:87,714,966...87,731,009

G

proteasome 20S subunit beta 4

increases expression

Cephaloridine results in increased expression of PSMB4 mRNA

NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746

G

polypyrimidine tract binding protein 1

increases expression

Cephaloridine results in increased expression of PTBP1 mRNA

NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397

G

prostaglandin reductase 1

increases expression

Cephaloridine results in increased expression of PTGR1 mRNA

NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666

G

protein tyrosine phosphatase, non-receptor type 11

decreases expression

Cephaloridine results in decreased expression of PTPN11 mRNA

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

G

protein tyrosine phosphatase, receptor type, B

decreases expression

Cephaloridine results in decreased expression of PTPRB mRNA

NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748

G

protein tyrosine phosphatase, receptor type N2

increases expression

Cephaloridine results in increased expression of PTPRN2 mRNA

NCBI chr 6:137,439,572...138,191,575
Ensembl chr 6:137,439,540...138,191,575

G

peptidyl-tRNA hydrolase 1 homolog

increases expression

Cephaloridine results in increased expression of PTRH1 mRNA

NCBI chr 3:16,064,867...16,071,098
Ensembl chr 3:16,064,880...16,070,648

G

PVR cell adhesion molecule

increases expression

Cephaloridine results in increased expression of PVR mRNA

NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715

G

RAB11 family interacting protein 3

decreases expression

Cephaloridine results in decreased expression of RAB11FIP3 mRNA

NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479

G

RAB31, member RAS oncogene family

decreases expression

Cephaloridine results in decreased expression of RAB31 mRNA

NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253

G

RAD18 E3 ubiquitin protein ligase

increases expression

Cephaloridine results in increased expression of RAD18 mRNA

NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069

G

RB transcriptional corepressor 1

affects activity

Cephaloridine affects the activity of RB1 protein

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

retinol binding protein 2

increases expression

Cephaloridine results in increased expression of RBP2 mRNA

NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473

G

rabenosyn, RAB effector

decreases expression

Cephaloridine results in decreased expression of RBSN mRNA

NCBI chr 4:124,682,228...124,712,578
Ensembl chr 4:124,683,969...124,712,578

G

retinol dehydrogenase 16

decreases expression

Cephaloridine results in decreased expression of RDH2 mRNA

NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124

G

RecQ like helicase 4

increases expression

Cephaloridine results in increased expression of RECQL4 mRNA

NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619

G

RELA proto-oncogene, NF-kB subunit

affects activity

Cephaloridine affects the activity of RELA protein

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

replication factor C subunit 3

increases expression

Cephaloridine results in increased expression of RFC3 mRNA

NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778

G

replication factor C subunit 4

increases expression

Cephaloridine results in increased expression of RFC4 mRNA

NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122

G

regucalcin

decreases expression

Cephaloridine results in decreased expression of RGN mRNA

PMID:8584014 PMID:18500788

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

G

regulator of G-protein signaling 11

increases expression

Cephaloridine results in increased expression of RGS11 mRNA

NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060

G

Rh family, C glycoprotein

increases expression

Cephaloridine results in increased expression of RHCG mRNA

NCBI chr 1:133,531,704...133,555,902
Ensembl chr 1:133,531,716...133,555,876

G

Rho-related BTB domain containing 1

decreases expression

Cephaloridine results in decreased expression of RHOBTB1 mRNA

NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012

G

rhophilin, Rho GTPase binding protein 2

increases expression

Cephaloridine results in increased expression of RHPN2 mRNA

NCBI chr 1:87,991,143...88,051,895
Ensembl chr 1:87,991,144...88,051,902

G

reactive intermediate imine deaminase A homolog

decreases expression

Cephaloridine results in decreased expression of RIDA mRNA

NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716

G

Rho family GTPase 1

increases expression

Cephaloridine results in increased expression of RND1 mRNA

NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399

G

ring finger protein 227

increases expression

Cephaloridine results in increased expression of RNF227 mRNA

NCBI chr10:54,061,054...54,063,015
Ensembl chr10:54,059,947...54,063,010

G

ribosomal protein L23A

increases expression

Cephaloridine results in increased expression of RPL23A mRNA

NCBI chr10:63,076,660...63,079,346
Ensembl chr10:63,076,066...63,079,346
Ensembl chr15:63,076,066...63,079,346

G

ribosomal protein L23A like 1

increases expression

Cephaloridine results in increased expression of RPL23AL1 mRNA

NCBI chr 2:38,452,814...38,453,384
Ensembl chr 2:38,451,401...38,453,417

G

ribosomal protein L32 like 4

decreases expression

Cephaloridine results in decreased expression of RPL32L4 mRNA

NCBI chr 8:84,691,128...84,692,042

G

ribonucleotide reductase regulatory subunit M2

decreases expression

Cephaloridine results in decreased expression of RRM2 mRNA

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

RUNX1 partner transcriptional co-repressor 1

decreases expression

Cephaloridine results in decreased expression of RUNX1T1 mRNA

NCBI chr 5:27,187,674...27,338,070
Ensembl chr 5:27,187,551...27,335,592

G

retinoid X receptor gamma

increases expression

Cephaloridine results in increased expression of RXRG mRNA

NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167

G

secretoglobin, family 3A, member 1

increases expression

Cephaloridine results in increased expression of SCGB3A1 mRNA

NCBI chr10:33,968,059...33,969,366
Ensembl chr10:33,968,059...33,969,476

G

secretoglobin, family 3A, member 2

increases expression

Cephaloridine results in increased expression of SCGB3A2 mRNA

NCBI chr18:35,932,840...35,935,762
Ensembl chr18:35,932,840...35,935,762

G

secretin

increases expression

Cephaloridine results in increased expression of SCT mRNA

NCBI chr 1:196,382,857...196,383,668
Ensembl chr 1:196,382,856...196,383,658

G

secreted and transmembrane 1B

increases expression

Cephaloridine results in increased expression of SECTM1A mRNA

NCBI chr10:106,324,070...106,333,779
Ensembl chr10:106,325,203...106,333,769

G

selenoprotein P

decreases expression

Cephaloridine results in decreased expression of SELENOP mRNA

NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852

G

semaphorin 4C

decreases expression

Cephaloridine results in decreased expression of SEMA4C mRNA

NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128

G

septin 10

decreases expression

Cephaloridine results in decreased expression of SEPTIN10 mRNA

NCBI chr20:27,101,764...27,194,997
Ensembl chr20:27,101,752...27,194,780

G

SH2B adaptor protein 2

increases expression

Cephaloridine results in increased expression of SH2B2 mRNA

NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844

G

SH3-domain binding protein 2

increases expression

Cephaloridine results in increased expression of SH3BP2 mRNA

NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251

G

shroom family member 4

decreases expression

Cephaloridine results in decreased expression of SHROOM4 mRNA

NCBI chr X:15,869,065...16,076,850
Ensembl chr X:15,869,065...16,076,869

G

sialic acid binding Ig-like lectin 5

increases expression

Cephaloridine results in increased expression of SIGLEC5 mRNA

NCBI chr 1:93,768,190...93,776,696
Ensembl chr 1:93,768,319...93,776,694

G

spindle and kinetochore associated complex subunit 1

decreases expression

Cephaloridine results in decreased expression of SKA1 mRNA

NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037

G

solute carrier family 15 member 3

increases expression

Cephaloridine results in increased expression of SLC15A3 mRNA

NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157

G

solute carrier family 16, member 12

decreases expression

Cephaloridine results in decreased expression of SLC16A12 mRNA

NCBI chr 1:232,184,004...232,262,170
Ensembl chr 1:232,185,907...232,262,141

G

solute carrier family 16, member 14

decreases expression

Cephaloridine results in decreased expression of SLC16A14 mRNA

NCBI chr 9:86,110,066...86,137,546
Ensembl chr 9:86,112,894...86,137,318

G

solute carrier family 1 member 5

increases expression

Cephaloridine results in increased expression of SLC1A5 mRNA

NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 22, member 23

decreases expression

Cephaloridine results in decreased expression of SLC22A23 mRNA

NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790

G

solute carrier family 22 member 5

decreases expression

Cephaloridine results in decreased expression of SLC22A5 mRNA

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

G

solute carrier family 22 member 6

increases import
multiple interactions
increases uptake

SLC22A6 protein results in increased import of Cephaloridine
Cephaloridine inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
SLC22A6 protein results in increased uptake of Cephaloridine

PMID:10594788 PMID:16098483

NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173

G

solute carrier family 22 member 8

increases uptake
multiple interactions

SLC22A8 protein results in increased uptake of Cephaloridine
Cephaloridine inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]

NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450

G

solute carrier family 35 member D2

increases expression

Cephaloridine results in increased expression of SLC35D2 mRNA

NCBI chr17:987,899...1,019,747
Ensembl chr17:988,157...1,019,743

G

solute carrier family 39 member 4

increases expression

Cephaloridine results in increased expression of SLC39A4 mRNA

NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553

G

solute carrier family 41 member 2

increases expression

Cephaloridine results in increased expression of SLC41A2 mRNA

NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166

G

solute carrier family 46, member 3

increases expression

Cephaloridine results in increased expression of SLC46A3 mRNA

NCBI chr12:7,140,610...7,157,093
Ensembl chr12:7,140,668...7,157,092

G

solute carrier family 4 member 4

decreases expression

Cephaloridine results in decreased expression of SLC4A4 mRNA

NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883

G

solute carrier family 5 member 3

increases expression

Cephaloridine results in increased expression of SLC5A3 mRNA

NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883

G

solute carrier family 7 member 10

increases expression

Cephaloridine results in increased expression of SLC7A10 mRNA

NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071

G

solute carrier family 7 member 5

increases expression

Cephaloridine results in increased expression of SLC7A5 mRNA

NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823

G

solute carrier family 7 member 7

decreases expression

Cephaloridine results in decreased expression of SLC7A7 mRNA

NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648

G

solute carrier family 8 member A1

decreases expression

Cephaloridine results in decreased expression of SLC8A1 mRNA

NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628

G

secretory leukocyte peptidase inhibitor

increases expression

Cephaloridine results in increased expression of SLPI mRNA

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

G

SET and MYND domain containing 1

increases expression

Cephaloridine results in increased expression of SMYD1 mRNA

NCBI chr 4:103,195,330...103,252,989
Ensembl chr 4:103,200,322...103,311,766

G

small nuclear RNA activating complex, polypeptide 2

increases expression

Cephaloridine results in increased expression of SNAPC2 mRNA

NCBI chr12:2,605,794...2,608,997
Ensembl chr12:2,605,810...2,608,999

G

suppressor of cytokine signaling 3

decreases expression

Cephaloridine results in decreased expression of SOCS3 mRNA

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

Spetex-2B protein

increases expression

Cephaloridine results in increased expression of SPETEX2B mRNA

G

Spetex-2D protein

increases expression

Cephaloridine results in increased expression of SPETEX2D mRNA

G

sphingosine kinase 1

increases expression

Cephaloridine results in increased expression of SPHK1 mRNA

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

serine peptidase inhibitor, Kazal type 1

decreases expression

Cephaloridine results in decreased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

SRP receptor subunit alpha

decreases expression

Cephaloridine results in decreased expression of SRPRA mRNA

NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470

G

signal transducer and activator of transcription 3

increases expression

Cephaloridine results in increased expression of STAT3 mRNA

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

serine/threonine kinase 35

increases expression

Cephaloridine results in increased expression of STK35 mRNA

NCBI chr 3:117,016,819...117,049,131
Ensembl chr 3:117,016,950...117,048,066

G

signaling receptor and transporter of retinol STRA6

decreases expression

Cephaloridine results in decreased expression of STRA6 mRNA

NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860

G

sulfotransferase family 1C member 2A

decreases expression

Cephaloridine results in decreased expression of SULT1C2 mRNA; Cephaloridine results in decreased expression of SULT1C2A mRNA

NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734

G

sulfotransferase family 4A, member 1

increases expression

Cephaloridine results in increased expression of SULT4A1 mRNA

NCBI chr 7:115,216,066...115,240,156
Ensembl chr 7:115,216,066...115,240,085

G

surfeit 6

decreases expression

Cephaloridine results in decreased expression of SURF6 mRNA

NCBI chr 3:10,221,450...10,232,306
Ensembl chr 3:10,221,452...10,232,251

G

sushi domain containing 2

decreases expression

Cephaloridine results in decreased expression of SUSD2 mRNA

NCBI chr20:13,017,516...13,024,820
Ensembl chr20:13,017,477...13,024,903

G

spectrin repeat containing nuclear envelope protein 1

decreases expression

Cephaloridine results in decreased expression of SYNE1 mRNA

NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322

G

spectrin repeat containing nuclear envelope protein 2

decreases expression

Cephaloridine results in decreased expression of SYNE2 mRNA

NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064

G

synaptotagmin-like 5

increases expression

Cephaloridine results in increased expression of SYTL5 mRNA

NCBI chr X:12,775,529...13,030,134
Ensembl chr X:12,788,698...13,030,175

G

tachykinin precursor 3

increases expression

Cephaloridine results in increased expression of TAC2 mRNA

NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170

G

T-box transcription factor 3

decreases expression

Cephaloridine results in decreased expression of TBX3 mRNA

NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708

G

transcription factor 12

decreases expression

Cephaloridine results in decreased expression of TCF12 mRNA

NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201

G

transcription factor 19

increases expression

Cephaloridine results in increased expression of TCF19 mRNA

NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271

G

transferrin receptor

increases expression

Cephaloridine results in increased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

TOPBP1-interacting checkpoint and replication regulator

increases expression

Cephaloridine results in increased expression of TICRR mRNA

NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523

G

timeless circadian regulator

increases expression

Cephaloridine results in increased expression of TIMELESS mRNA

NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738

G

TIMP metallopeptidase inhibitor 1

increases expression

Cephaloridine results in increased expression of TIMP1 mRNA

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

toll-like receptor 2

increases expression

Cephaloridine results in increased expression of TLR2 mRNA

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

transmembrane protein 163

increases expression

Cephaloridine results in increased expression of TMEM163 mRNA

NCBI chr13:38,967,913...39,141,664
Ensembl chr13:38,968,101...39,141,452

G

transmembrane protein 252

decreases expression

Cephaloridine results in decreased expression of TMEM252 mRNA

NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943

G

transmembrane protein 270

increases expression

Cephaloridine results in increased expression of TMEM270 mRNA

NCBI chr12:21,793,631...21,798,723
Ensembl chr12:21,794,130...21,798,731

G

transmembrane protein 63c

increases expression

Cephaloridine results in increased expression of TMEM63C mRNA

NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990

G

transmembrane protein 86A

decreases expression

Cephaloridine results in decreased expression of TMEM86A mRNA

NCBI chr 1:97,595,910...97,600,260
Ensembl chr 1:97,595,842...97,600,260

G

TNF receptor superfamily member 12A

increases expression

Cephaloridine results in increased expression of TNFRSF12A mRNA

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 1A

increases expression

Cephaloridine results in increased expression of TNFRSF1A mRNA

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

tensin 1

decreases expression

Cephaloridine results in decreased expression of TNS1 mRNA

NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225

G

tensin 4

increases expression

Cephaloridine results in increased expression of TNS4 mRNA

NCBI chr10:84,021,965...84,041,346
Ensembl chr10:84,021,966...84,041,346

G

tonsoku-like, DNA repair protein

increases expression

Cephaloridine results in increased expression of TONSL mRNA

NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750

G

DNA topoisomerase II alpha

decreases expression

Cephaloridine results in decreased expression of TOP2A mRNA

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

tryptophan hydroxylase 1

increases expression

Cephaloridine results in increased expression of TPH1 mRNA

NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344

G

tribbles pseudokinase 3

increases expression

Cephaloridine results in increased expression of TRIB3 mRNA

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

TLR4 interactor with leucine-rich repeats

decreases expression

Cephaloridine results in decreased expression of TRIL mRNA

NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172

G

transient receptor potential cation channel, subfamily C, member 6

increases expression

Cephaloridine results in increased expression of TRPC6 mRNA

NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092

G

tetratricopeptide repeat domain 39A

increases expression

Cephaloridine results in increased expression of TTC39A mRNA

NCBI chr 5:124,165,102...124,204,740
Ensembl chr 5:124,151,760...124,204,973

G

Ttk protein kinase

decreases expression

Cephaloridine results in decreased expression of TTK mRNA

NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651

G

tubulin tyrosine ligase like 2

increases expression

Cephaloridine results in increased expression of TTLL2 mRNA

NCBI chr 1:52,967,183...52,976,690
Ensembl chr 1:52,968,408...52,976,697

G

tubulin, beta 3 class III

increases expression

Cephaloridine results in increased expression of TUBB3 mRNA

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

G

tubulin, beta 6 class V

increases expression

Cephaloridine results in increased expression of TUBB6 mRNA

NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418

G

thymidylate synthetase

increases expression

Cephaloridine results in increased expression of TYMS mRNA

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

ubiquitin D

increases expression

Cephaloridine results in increased expression of UBD mRNA

NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639

G

ubiquitin-conjugating enzyme E2C

decreases expression

Cephaloridine results in decreased expression of UBE2C mRNA

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

G

ubiquitin-conjugating enzyme E2L 6

increases expression

Cephaloridine results in increased expression of UBE2L6 mRNA

NCBI chr 3:69,873,025...69,888,042
Ensembl chr 3:69,873,424...69,888,048

G

ubiquitin-like 7

increases expression

Cephaloridine results in increased expression of UBL7 mRNA

NCBI chr 8:58,321,279...58,340,353
Ensembl chr 8:58,320,866...58,340,344

G

ubiquitin C-terminal hydrolase L1

increases expression

Cephaloridine results in increased expression of UCHL1 mRNA

NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases expression

Cephaloridine results in increased expression of UGT1A2 mRNA

NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A6

increases expression

Cephaloridine results in increased expression of UGT1A6 mRNA

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 2 member B7

increases expression

Cephaloridine results in increased expression of UGT2B7 mRNA

NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604

G

U2AF homology motif kinase 1

increases expression

Cephaloridine results in increased expression of UHMK1 mRNA

NCBI chr13:82,396,646...82,416,292
Ensembl chr13:82,401,187...82,416,292

G

U2AF homology motif kinase 1l1

increases expression

Cephaloridine results in increased expression of UHMK1L1 mRNA

NCBI chr17:42,241,640...42,243,666

G

uridine phosphorylase 1

increases expression

Cephaloridine results in increased expression of UPP1 mRNA

NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462

G

ubiquitin specific peptidase 24

decreases expression

Cephaloridine results in decreased expression of USP24 mRNA

NCBI chr 5:121,080,687...121,210,321
Ensembl chr 5:121,080,470...121,210,311

G

vascular cell adhesion molecule 1

increases expression

Cephaloridine results in increased expression of VCAM1 mRNA

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

G

V-set pre-B cell surrogate light chain 3

increases expression

Cephaloridine results in increased expression of VPREB3 mRNA

NCBI chr20:12,717,421...12,718,785
Ensembl chr20:12,716,779...12,719,520

G

WD repeat and HMG-box DNA binding protein 1

increases expression

Cephaloridine results in increased expression of WDHD1 mRNA

NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096

G

zinc finger CCCH type containing 13

decreases expression

Cephaloridine results in decreased expression of ZC3H13 mRNA

NCBI chr15:50,607,335...50,671,802
Ensembl chr15:50,607,380...50,671,802

G

zinc finger DHHC-type palmitoyltransferase 18

decreases expression

Cephaloridine results in decreased expression of ZDHHC18 mRNA

NCBI chr 5:145,821,534...145,859,989
Ensembl chr 5:145,831,446...145,859,993

G

zinc finger AN1-type containing 2A

decreases expression

Cephaloridine results in decreased expression of ZFAND2A mRNA

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

G

zinc finger protein 367

increases expression

Cephaloridine results in increased expression of ZFP367 mRNA

NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287

cefalotin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily C member 2

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

BCL2 associated X, apoptosis regulator

increases expression

Cephalothin results in increased expression of BAX protein

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

caspase 3

multiple interactions

Cephalothin results in increased cleavage of and results in increased activity of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cytochrome P450 family 8 subfamily B member 1

multiple interactions

[Cephalothin co-treated with Neomycin] results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

fibroblast growth factor 19

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of FGF15 mRNA

NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287

G

NPC1 like intracellular cholesterol transporter 1

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of NPC1L1 mRNA

NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113

G

nuclear receptor subfamily 5, group A, member 2

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of NR5A2 mRNA

NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326

G

solute carrier family 10 member 1

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 25 member 20

multiple interactions

Cephalothin binds to and results in decreased activity of SLC25A20 protein; Cephalothin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]

NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512

G

SLC51 subunit beta

multiple interactions

[Cephalothin co-treated with Neomycin] results in decreased expression of SLC51B mRNA

NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145

G

solute carrier organic anion transporter family member 1B2

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of SLCO1B2 mRNA

NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981

G

tumor protein p53

increases expression

Cephalothin results in increased expression of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

vitamin D receptor

multiple interactions

[Cephalothin co-treated with Neomycin] results in increased expression of VDR mRNA

NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677

cefotiam

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

solute carrier family 22 member 6

multiple interactions

Cefotiam inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]

NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173

G

solute carrier family 22 member 8

increases uptake
multiple interactions

SLC22A8 protein results in increased uptake of Cefotiam
Cefotiam inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]

NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450

cefoxitin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

interferon gamma

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IFNG mRNA]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

inhibitor of nuclear factor kappa B kinase subunit beta

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA]

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 10

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IL10 mRNA]

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 1 beta

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IL1B mRNA]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IL6 mRNA]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

MYD88, innate immune signal transduction adaptor

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of MYD88 mRNA]

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of RELA mRNA]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RT1 class I, locus CE16

affects expression

Cefoxitin affects the expression of HLA-A mRNA

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

G

RT1 class II, locus Ha

affects expression

Cefoxitin affects the expression of HLA-DPA1 mRNA

NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244

G

transforming growth factor, beta 1

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TGFB1 mRNA]

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

toll-like receptor 2

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TLR2 mRNA]

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

tumor necrosis factor

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TNF mRNA]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor associated factor 6

multiple interactions

[Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TRAF6 mRNA]

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

cephalexin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RT1 class II, locus Ha

affects expression

Cephalexin affects the expression of HLA-DPA1 mRNA

NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244

G

solute carrier family 15 member 1

increases transport

SLC15A1 protein results in increased transport of Cephalexin

NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545

clindamycin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
increases expression

Clindamycin results in increased expression of and results in increased activity of CYP3A4 protein
Clindamycin results in increased expression of CYP3A4 mRNA

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

matrix metallopeptidase 13

increases expression

Clindamycin results in increased expression of MMP13 mRNA

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

RT1 class Ia, locus A2

affects expression

Clindamycin affects the expression of HLA-E mRNA

NCBI chr20:4,870,939...4,910,183

G

RT1 class II, locus Db1

affects expression

Clindamycin affects the expression of HLA-DRB1 mRNA

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

clindamycin phosphate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

paraoxonase 1

decreases activity

clindamycin phosphate results in decreased activity of PON1 protein

NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360

cloxacillin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

decreases activity

Cloxacillin results in decreased activity of ABCB11 protein

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

caspase 3

increases activity
multiple interactions

Cloxacillin results in increased activity of CASP3 protein
[Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Cloxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

interleukin 1 beta

multiple interactions

[Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

[Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

tumor necrosis factor

multiple interactions

[Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

dihydroergotamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

decreases activity

Dihydroergotamine results in decreased activity of ABCB11 protein

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily B member 4

decreases activity

Dihydroergotamine results in decreased activity of ABCB4 protein

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
decreases activity
increases activity

Dihydroergotamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Dihydroergotamine results in decreased activity of CYP1A1 protein
Dihydroergotamine results in increased activity of CYP1A1 protein

PMID:18420780 PMID:18493746 PMID:33814510

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases activity

Dihydroergotamine results in decreased activity of CYP1B1 protein

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 2, subfamily a, polypeptide 3

decreases activity

Dihydroergotamine results in decreased activity of CYP2A4 protein

NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases activity

Dihydroergotamine results in decreased activity of CYP2B10 protein

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases activity

Dihydroergotamine results in decreased activity of CYP2C29 protein

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases activity

Dihydroergotamine results in decreased activity of CYP2D6 protein
Dihydroergotamine results in decreased activity of CYP2D22 protein

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases activity

Dihydroergotamine results in decreased activity of CYP3A4 protein

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

5-hydroxytryptamine (serotonin) receptor 5B

multiple interactions

dihydroergotamine binds to protein 5-Htr5b; inhibits the reaction[5-carboxamidotryptamine binds to 5-Htr5b]

RGD

NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835

G

interleukin 24

increases expression

Dihydroergotamine results in increased expression of IL24 mRNA

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

nuclear receptor subfamily 1, group I, member 2

increases activity

Dihydroergotamine results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

eprinomectin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

decreases activity

eprinomectin results in decreased activity of ABCB1A protein

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

anoctamin 1

decreases activity

eprinomectin results in decreased activity of ANO1 protein

NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069

G

nuclear receptor coactivator 2

multiple interactions

eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]

NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451

G

nuclear receptor subfamily 1, group H, member 4

multiple interactions

eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

KT 5720

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

multiple interactions

KT 5720 inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily B member 1A

decreases activity

KT 5720 results in decreased activity of ABCB1 protein

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

multiple interactions

KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]
KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]; KT 5720 inhibits the reaction [Taurolithocholic Acid results in decreased activity of and affects the localization of ABCC2 protein]

PMID:26049102 PMID:29052767 PMID:31300867

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

adrenoceptor alpha 1A

multiple interactions

KT 5720 inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

G

AKT serine/threonine kinase 1

multiple interactions

KT 5720 inhibits the reaction [Taurolithocholic Acid results in increased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

amyloid beta precursor protein

multiple interactions

KT 5720 inhibits the reaction [cilostazol inhibits the reaction [APP protein results in decreased expression of and results in decreased activity of SIRT1 protein]]

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

activating transcription factor 2

multiple interactions

KT 5720 inhibits the reaction [Bucladesine results in increased expression of ATF2 protein modified form]

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

calcitonin-related polypeptide alpha

multiple interactions

KT 5720 inhibits the reaction [NPPA protein results in increased secretion of CALCA protein]

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

G

CART prepropeptide

multiple interactions

KT 5720 inhibits the reaction [CARTPT protein results in increased phosphorylation of GRIN1 protein]

NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713

G

caspase 3

multiple interactions

KT 5720 inhibits the reaction [cilostazol results in increased activity of CASP3 protein]; KT 5720 inhibits the reaction [Colforsin results in increased activity of CASP3 protein]
KT 5720 inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP3 protein]
KT 5720 inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]

PMID:20131233 PMID:21873648 PMID:32115946

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cholinergic receptor, muscarinic 1

multiple interactions

KT 5720 affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]; KT 5720 promotes the reaction [Acetylcholine binds to CHRM1 protein]; KT 5720 promotes the reaction [N-Methylscopolamine binds to CHRM1 protein]; Staurosporine affects the reaction [KT 5720 promotes the reaction [N-Methylscopolamine binds to CHRM1 protein]]

PMID:10860942 PMID:16439611

NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356

G

cholinergic receptor, muscarinic 2

multiple interactions

KT 5720 promotes the reaction [N-Methylscopolamine binds to CHRM2 protein]

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

cholinergic receptor, muscarinic 3

affects binding

KT 5720 binds to CHRM3 protein

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

cell death-inducing DFFA-like effector c

multiple interactions

KT 5720 inhibits the reaction [Isoproterenol results in increased expression of CIDEC protein]

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

casein kinase 2 alpha 1

multiple interactions

KT 5720 inhibits the reaction [cilostazol results in increased phosphorylation of CSNK2A1 protein]

NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696

G

E1A binding protein p300

multiple interactions

KT 5720 inhibits the reaction [cilostazol affects the expression of EP300 protein]

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

fibroblast growth factor 1

multiple interactions

KT 5720 inhibits the reaction [Norepinephrine inhibits the reaction [Carbachol results in increased expression of FGF1 protein]]

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

G protein-coupled estrogen receptor 1

multiple interactions

KT 5720 inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glutamate ionotropic receptor NMDA type subunit 1

multiple interactions

KT 5720 inhibits the reaction [CARTPT protein results in increased phosphorylation of GRIN1 protein]

NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603

G

glutathione S-transferase alpha 1

multiple interactions

KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA1 mRNA]

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

multiple interactions

KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA2 mRNA]

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 4

multiple interactions

KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA4 mRNA]

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

heme oxygenase 1

multiple interactions

KT 5720 inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]
Dinoprostone inhibits the reaction [KT 5720 promotes the reaction [Lipopolysaccharides results in increased activity of HMOX1 protein]]; KT 5720 inhibits the reaction [Dinoprostone inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]]; KT 5720 promotes the reaction [Lipopolysaccharides results in increased activity of HMOX1 protein]; KT 5720 promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]

PMID:16439612 PMID:24003391

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

interleukin 1 beta

multiple interactions

KT 5720 inhibits the reaction [Dipyridamole promotes the reaction [IL1B protein results in increased abundance of Cyclic AMP]]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

integrin subunit alpha M

multiple interactions

KT 5720 inhibits the reaction [2-(2-fluorobenzamido)benzoate ethyl ester inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGAM protein]]

NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

KT 5720 inhibits the reaction [Bucladesine results in increased expression of JUN protein modified form]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of JUN protein]

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

LDL receptor related protein 1

multiple interactions

KT 5720 inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

mitogen activated protein kinase 1

multiple interactions

KT 5720 inhibits the reaction [Terbutaline inhibits the reaction [Shiga Toxin results in increased expression of MAPK1 protein]]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

KT 5720 inhibits the reaction [Terbutaline inhibits the reaction [Shiga Toxin results in increased expression of MAPK3 protein]]

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

nitric oxide synthase 1

multiple interactions

KT 5720 inhibits the reaction [Mevinphos results in increased expression of NOS1 protein]

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

G

natriuretic peptide A

multiple interactions

KT 5720 inhibits the reaction [NPPA protein results in increased secretion of CALCA protein]

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

G

nucleobindin 2

multiple interactions

KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium]

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

phospholipase A2 group VI

multiple interactions

KT 5720 inhibits the reaction [UCN protein results in decreased expression of PLA2G6 protein]

NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114

G

protein kinase cAMP-activated catalytic subunit alpha

multiple interactions

KT 5720 inhibits the reaction [Bucladesine results in increased activity of PRKACA protein]; KT 5720 inhibits the reaction [Taurolithocholic Acid results in increased activity of PRKACA protein]

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[KT 5720 co-treated with Dinoprostone] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; KT 5720 affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

sirtuin 1

multiple interactions

KT 5720 inhibits the reaction [cilostazol inhibits the reaction [APP protein results in decreased expression of and results in decreased activity of SIRT1 protein]]; KT 5720 inhibits the reaction [cilostazol results in increased phosphorylation of SIRT1 protein]

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

solute carrier family 1 member 2

multiple interactions

KT 5720 inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]

NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498

G

suppressor of cytokine signaling 3

multiple interactions

KT 5720 inhibits the reaction [isoeugenol results in increased expression of SOCS3 mRNA]

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

tyrosine hydroxylase

decreases expression
multiple interactions

KT 5720 results in decreased expression of TH mRNA
KT 5720 inhibits the reaction [Colforsin results in increased expression of TH mRNA]; KT 5720 inhibits the reaction [HU 211 results in decreased expression of TH mRNA]

NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767

G

tumor necrosis factor

multiple interactions

KT 5720 inhibits the reaction [Terbutaline inhibits the reaction [Shiga Toxin results in increased expression of TNF mRNA]]; KT 5720 inhibits the reaction [Terbutaline results in decreased expression of TNF mRNA]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF superfamily member 11

multiple interactions

KT 5720 inhibits the reaction [modafinil results in increased expression of TNFSF11 mRNA]

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

G

urocortin

multiple interactions

KT 5720 inhibits the reaction [UCN protein results in decreased expression of PLA2G6 protein]

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

G

zinc finger protein 36

multiple interactions

KT 5720 inhibits the reaction [isoeugenol results in increased expression of ZFP36 protein]

NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564

O-(chloroacetylcarbamoyl)fumagillol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cyclin D1

increases expression

O-(chloroacetylcarbamoyl)fumagillol results in increased expression of CCND1 protein

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin-dependent kinase inhibitor 1A

increases expression

O-(chloroacetylcarbamoyl)fumagillol results in increased expression of CDKN1A protein

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

fibroblast growth factor 2

multiple interactions
decreases expression

[O-(chloroacetylcarbamoyl)fumagillol co-treated with docetaxel] results in decreased expression of FGF2 protein
O-(chloroacetylcarbamoyl)fumagillol results in decreased expression of FGF2 protein

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

matrix metallopeptidase 9

multiple interactions

[O-(chloroacetylcarbamoyl)fumagillol co-treated with docetaxel] results in decreased expression of MMP9 protein

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

nuclear factor kappa B subunit 1

multiple interactions

O-(chloroacetylcarbamoyl)fumagillol inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]]

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nitric oxide synthase 2

multiple interactions

O-(chloroacetylcarbamoyl)fumagillol inhibits the reaction [Diethylnitrosamine results in increased activity of NOS2 protein]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

RB transcriptional corepressor 1

decreases phosphorylation

O-(chloroacetylcarbamoyl)fumagillol results in decreased phosphorylation of RB1 protein

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

O-(chloroacetylcarbamoyl)fumagillol inhibits the reaction [Diethylnitrosamine results in increased activity of [NFKB1 protein binds to RELA protein]]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

superoxide dismutase 2

multiple interactions

O-(chloroacetylcarbamoyl)fumagillol inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of and results in increased activity of SOD2 protein]

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

tumor protein p53

increases expression

O-(chloroacetylcarbamoyl)fumagillol results in increased expression of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

oxycodone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 8

increases expression

Oxycodone results in increased expression of ABCA8 mRNA

NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988

G

ATP binding cassette subfamily B member 1A

increases expression

Oxycodone results in increased expression of ABCB1A mRNA; Oxycodone results in increased expression of ABCB1A protein

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily B member 4

increases expression

Oxycodone results in increased expression of ABCB4 mRNA

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily G member 1

decreases expression

Oxycodone results in decreased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 5

increases expression

Oxycodone results in increased expression of ABCG5 mRNA

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

abhydrolase domain containing 6, acylglycerol lipase

increases expression

Oxycodone results in increased expression of ABHD6 mRNA

NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985

G

acyl-CoA synthetase medium-chain family member 2

increases expression

Oxycodone results in increased expression of ACSM2A mRNA

NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116

G

actinin, alpha 1

decreases expression

Oxycodone results in decreased expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

ADAM metallopeptidase domain 17

decreases expression

Oxycodone results in decreased expression of ADAM17 mRNA

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

increases expression

Oxycodone results in increased expression of ADAMTS1 mRNA

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

adhesion G protein-coupled receptor E1

decreases expression

Oxycodone results in decreased expression of ADGRE1 mRNA

NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000

G

aryl hydrocarbon receptor

increases expression