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ONTOLOGY REPORT - ANNOTATIONS


Term:alogliptin
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Accession:CHEBI:72323 term browser browse the term
Definition:A piperidine that is 3-methyl-2,4-dioxo-3,4-dihydropyrimidine carrying additional 2-cyanobenzyl and 3-aminopiperidin-1-yl groups at positions 1 and 2 respectively (the R-enantiomer). Used in the form of its benzoate salt for treatment of type 2 diabetes.
Synonyms:exact_synonym: 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile
 related_synonym: Formula=C18H21N5O2;   InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1;   InChIKey=ZSBOMTDTBDDKMP-OAHLLOKOSA-N;   SMILES=Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2ccccc2C#N)c1=O;   alogliptina;   alogliptine;   alogliptinum
 xref: CAS:850649-61-5 "ChemIDplus";   Drug_Central:4340 "DrugCentral"
 xref_mesh: MESH:C520853
 xref: PMID:20040339 "Europe PMC";   PMID:21205126 "Europe PMC";   PMID:21397040 "Europe PMC";   PMID:21431099 "Europe PMC";   PMID:21558879 "Europe PMC";   PMID:21595274 "Europe PMC";   PMID:21595275 "Europe PMC";   PMID:21682833 "Europe PMC";   PMID:21733058 "Europe PMC";   PMID:21806314 "Europe PMC";   PMID:22106975 "Europe PMC";   PMID:22162539 "Europe PMC";   PMID:22237690 "Europe PMC";   PMID:22249941 "Europe PMC";   PMID:22296609 "Europe PMC";   PMID:22419732 "Europe PMC";   PMID:22429011 "Europe PMC";   PMID:22512582 "Europe PMC";   PMID:22583697 "Europe PMC";   PMID:22651127 "Europe PMC";   PMID:22832924 "Europe PMC";   PMID:23220949 "Europe PMC";   PMID:23289982 "Europe PMC";   PMID:23298374 "Europe PMC";   Patent:EP1970063;   Patent:US2007066635;   Patent:US2009275750;   Patent:WO2008028914;   Patent:WO2009022009;   Patent:WO2010072680;   Reaxys:10587993 "Reaxys";   Wikipedia:Alogliptin
 cyclic_relationship: is_conjugate_base_of CHEBI:72326


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alogliptin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19614
    chemical entity 19612
      group 19527
        pseudohalo group 2769
          cyano group 2769
            nitrile 2769
              alogliptin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    main group molecular entity 19489
                      s-block molecular entity 19262
                        hydrogen molecular entity 19253
                          hydrides 18169
                            inorganic hydride 17110
                              pnictogen hydride 17068
                                nitrogen hydride 16891
                                  azane 16565
                                    ammonia 16562
                                      organic amino compound 16561
                                        primary amino compound 6637
                                          alogliptin 1
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