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Accession:CHEBI:72296 term browser browse the term
Definition:A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases.
Synonyms:exact_synonym: 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
 related_synonym: BMS-562247;   BMS-562247-01;   Eliquis;   Formula=C25H25N5O4;   InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32);   InChIKey=QNZCBYKSOIHPEH-UHFFFAOYSA-N;   SMILES=COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)N1CCCCC1=O;   apixabanum
 xref: CAS:503612-47-3 "ChemIDplus";   CAS:503612-47-3 "KEGG DRUG";   DrugBank:DB06605;   KEGG:D03213;   PDBeChem:GG2;   PMID:21318583 "Europe PMC";   PMID:21954450 "Europe PMC";   PMID:21985171 "Europe PMC";   PMID:22250655 "Europe PMC";   PMID:22398784 "Europe PMC";   PMID:22686618 "Europe PMC";   PMID:22759198 "Europe PMC";   PMID:23033347 "Europe PMC";   PMID:23043068 "Europe PMC";   PMID:23179181 "Europe PMC";   PMID:23212107 "Europe PMC";   PMID:23218999 "Europe PMC";   PMID:23292264 "Europe PMC";   PMID:23292752 "Europe PMC";   PMID:23305476 "Europe PMC";   PMID:23312927 "Europe PMC";   PMID:23337923 "Europe PMC";   PMID:23342716 "Europe PMC";   PMID:23344716 "Europe PMC";   PMID:23351997 "Europe PMC";   Patent:US2007259913;   Patent:WO2007022165;   Patent:WO2008031782;   Patent:WO2010030983;   Reaxys:11244786 "Reaxys";   Wikipedia:Apixaban

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  CHEBI ontology 19679
    role 19623
      application 19246
        pharmaceutical 19108
          drug 19108
            hematologic agent 4249
              anticoagulant 4045
                apixaban 0
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  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                lactam 2856
                                                  apixaban 0
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