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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrithiamine
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Accession:CHEBI:72290 term browser browse the term
Definition:A pyridinium ion that is 3-(2-hydroxyethyl)-2-methylpyridine substituted at position 1 by a (4-amino-2-methylpyrimidin-5-yl)methyl group.
Synonyms:related_synonym: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium;   1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-HYDROXYETHYL)-2-METHYLPYRIDINIUM;   Formula=C14H19N4O;   InChI=1S/C14H19N4O/c1-10-12(5-7-19)4-3-6-18(10)9-13-8-16-11(2)17-14(13)15/h3-4,6,8,19H,5,7,9H2,1-2H3,(H2,15,16,17)/q+1;   InChIKey=PZWYDZMWPANLMB-UHFFFAOYSA-N;   SMILES=Cc1ncc(C[n+]2cccc(CCO)c2C)c(N)n1;   pyrithiamine cation
 alt_id: CHEBI:39662
 xref_mesh: MESH:D011745
 xref: PDBeChem:218;   Reaxys:3913157


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pyrithiamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfap glial fibrillary acidic protein increases expression EXP Pyrithiamine results in increased expression of GFAP protein CTD PMID:27984051 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Itgam integrin subunit alpha M increases expression EXP Pyrithiamine results in increased expression of ITGAM protein CTD PMID:27984051 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression EXP Pyrithiamine results in decreased expression of SLC2A1 protein CTD PMID:27984051 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19772
        ion 15946
          organic ion 8466
            organic cation 7321
              pyridinium ion 2405
                pyrithiamine 3
                  1-(4-amino-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                  pyrithiamine pyrophosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    main group molecular entity 19662
                      p-block molecular entity 19662
                        carbon group molecular entity 19579
                          organic molecular entity 19569
                            organic ion 8466
                              organic cation 7321
                                pyridinium ion 2405
                                  pyrithiamine 3
                                    1-(4-amino-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                                    pyrithiamine pyrophosphate 0
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