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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrithiamine
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Accession:CHEBI:72290 term browser browse the term
Definition:A pyridinium ion that is 3-(2-hydroxyethyl)-2-methylpyridine substituted at position 1 by a (4-amino-2-methylpyrimidin-5-yl)methyl group.
Synonyms:related_synonym: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium;   1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-HYDROXYETHYL)-2-METHYLPYRIDINIUM;   Formula=C14H19N4O;   InChI=1S/C14H19N4O/c1-10-12(5-7-19)4-3-6-18(10)9-13-8-16-11(2)17-14(13)15/h3-4,6,8,19H,5,7,9H2,1-2H3,(H2,15,16,17)/q+1;   InChIKey=PZWYDZMWPANLMB-UHFFFAOYSA-N;   SMILES=Cc1ncc(C[n+]2cccc(CCO)c2C)c(N)n1;   pyrithiamine cation
 alt_id: CHEBI:39662
 xref_mesh: MESH:D011745
 xref: PDBeChem:218;   Reaxys:3913157



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pyrithiamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfap glial fibrillary acidic protein increases expression EXP Pyrithiamine results in increased expression of GFAP protein CTD PMID:27984051 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Itgam integrin subunit alpha M increases expression EXP Pyrithiamine results in increased expression of ITGAM protein CTD PMID:27984051 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression EXP Pyrithiamine results in decreased expression of SLC2A1 protein CTD PMID:27984051 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20069
    chemical entity 20068
      molecular entity 20068
        ion 16477
          organic ion 9208
            organic cation 8143
              pyridinium ion 2413
                pyrithiamine 3
                  1-(4-amino-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                  pyrithiamine pyrophosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20069
    subatomic particle 20068
      composite particle 20068
        hadron 20068
          baryon 20068
            nucleon 20068
              atomic nucleus 20068
                atom 20068
                  main group element atom 19969
                    main group molecular entity 19969
                      p-block molecular entity 19969
                        carbon group molecular entity 19892
                          organic molecular entity 19885
                            organic ion 9208
                              organic cation 8143
                                pyridinium ion 2413
                                  pyrithiamine 3
                                    1-(4-amino-2-methylpyrimidin-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium bromide 0
                                    pyrithiamine pyrophosphate 0
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