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ONTOLOGY REPORT - ANNOTATIONS


Term:tolmetin
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Accession:CHEBI:71941 term browser browse the term
Definition:A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Synonyms:exact_synonym: [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
 related_synonym: 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid;   1-Methyl-5-p-toluoylpyrrole-2-acetic acid;   5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid;   Formula=C15H15NO3;   InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18);   InChIKey=UPSPUYADGBWSHF-UHFFFAOYSA-N;   SMILES=Cc1ccc(cc1)C(=O)c1ccc(CC(O)=O)n1C;   tolmetina;   tolmetine;   tolmetino;   tolmetinum
 alt_id: CHEBI:9618
 xref: CAS:26171-23-3 "ChemIDplus";   CAS:26171-23-3 "KEGG COMPOUND";   CAS:26171-23-3 "NIST Chemistry WebBook";   DrugBank:DB00500;   Drug_Central:2699 "DrugCentral";   HMDB:HMDB0014643;   KEGG:C07149;   KEGG:D02355;   LINCS:LSM-3852
 xref_mesh: MESH:D014046
 xref: PDBeChem:TLT;   PMID:1206489 "Europe PMC";   PMID:19181568 "Europe PMC";   PMID:19505209 "Europe PMC";   PMID:20529813 "Europe PMC";   PMID:20582193 "Europe PMC";   PMID:20853464 "Europe PMC";   PMID:21936545 "Europe PMC";   PMID:22005020 "Europe PMC";   PMID:22943177 "Europe PMC";   PMID:23333829 "Europe PMC";   PMID:3390998 "Europe PMC";   PMID:445955 "Europe PMC";   PMID:6686452 "Europe PMC";   PMID:8472518 "Europe PMC";   Patent:DE2836902;   Patent:MX2010012712;   Patent:WO2004069782;   Patent:WO2008017903;   Patent:WO2009072139;   Reaxys:485305 "Reaxys";   Wikipedia:Tolmetin
 cyclic_relationship: is_conjugate_acid_of CHEBI:72213


show annotations for term's descendants       view all columns           Sort by:
 
tolmetin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Glo1 glyoxalase 1 JBrowse link 20 9,273,589 9,291,608 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:6480464
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:6480464
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        anti-inflammatory agent 14907
          anti-inflammatory drug 13590
            non-steroidal anti-inflammatory drug 12666
              tolmetin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          tolmetin 6
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