Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.5.1.23 (ceramidase) inhibitor
go back to main search page
Accession:CHEBI:71551 term browser browse the term
Definition:An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of ceramidase (EC 3.5.1.23).
Synonyms:related_synonym: AC inhibitor;   AC inhibitors;   EC 3.5.1.23 inhibitor;   EC 3.5.1.23 inhibitors;   N-acylsphingosine amidohydrolase inhibitor;   N-acylsphingosine amidohydrolase inhibitors;   acid ceramidase inhibitor;   acid ceramidase inhibitors;   acylsphingosine deacylase inhibitor;   acylsphingosine deacylase inhibitors;   ceramidase (EC 3.5.1.23) inhibitors;   ceramidase inhibitor;   ceramidase inhibitors;   glycosphingolipid ceramide deacylase inhibitor;   glycosphingolipid ceramide deacylase inhibitors


show annotations for term's descendants           Sort by:
 
oleoyl ethanolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha increases response to substance
multiple interactions
ISO PPARA results in increased susceptibility to N-oleoylethanolamine
N-oleoylethanolamine binds to and results in increased activity of PPARA protein
CTD PMID:17906680 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO N-oleoylethanolamine results in decreased expression of PTGS2 protein CTD PMID:17906680 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19801
    role 19747
      biological role 19746
        biochemical role 19251
          enzyme inhibitor 18173
            EC 3.* (hydrolase) inhibitor 17664
              EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 17566
                EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor 17566
                  EC 3.5.1.23 (ceramidase) inhibitor 2
                    oleoyl ethanolamide + 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.