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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.5.1.23 (ceramidase) inhibitor
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Accession:CHEBI:71551 term browser browse the term
Definition:An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of ceramidase (EC 3.5.1.23).
Synonyms:related_synonym: AC inhibitor;   AC inhibitors;   EC 3.5.1.23 (ceramidase) inhibitors;   EC 3.5.1.23 inhibitor;   EC 3.5.1.23 inhibitors;   N-acylsphingosine amidohydrolase inhibitor;   N-acylsphingosine amidohydrolase inhibitors;   acid ceramidase inhibitor;   acid ceramidase inhibitors;   acylsphingosine deacylase inhibitor;   acylsphingosine deacylase inhibitors;   ceramidase inhibitor;   ceramidase inhibitors;   glycosphingolipid ceramide deacylase inhibitor;   glycosphingolipid ceramide deacylase inhibitors



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oleoyl ethanolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases export ISO ABCB1 protein results in increased export of N-oleoylethanolamine CTD PMID:30102254 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance
multiple interactions
ISO PPARA results in increased susceptibility to N-oleoylethanolamine
N-oleoylethanolamine binds to and results in increased activity of PPARA protein
CTD PMID:17906680 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO N-oleoylethanolamine results in decreased expression of PTGS2 protein CTD PMID:17906680 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          enzyme inhibitor 18380
            EC 3.* (hydrolase) inhibitor 17925
              EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 17804
                EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor 17804
                  EC 3.5.1.23 (ceramidase) inhibitor 3
                    oleoyl ethanolamide + 3
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