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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:71338 term browser browse the term
Definition:A signalling molecule produced and used by bacteria participating in quorum sensing, that is, in cell-cell communication to coordinate community-wide regulation of processes such as biofilm formation, virulence, and bioluminescence in populations of bacteria. Such communication can occur both within and between different species of bacteria.
Synonyms:related_synonym: autoinducers
 xref: Wikipedia:Autoinducer

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N-(3-oxododecanoyl)homoserine lactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO N-(3-oxododecanoyl)homoserine lactone results in increased activity of CASP3 protein CTD PMID:25627690 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity ISO N-(3-oxododecanoyl)homoserine lactone results in increased activity of CASP7 protein CTD PMID:25627690 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G P2ry2 purinergic receptor P2Y2 multiple interactions
decreases expression
ISO Ibuprofen inhibits the reaction [N-(3-oxododecanoyl)homoserine lactone results in decreased expression of P2RY2 mRNA] CTD PMID:10496880 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 decreases expression ISO N-(3-oxododecanoyl)homoserine lactone results in decreased expression of P2RY4 mRNA CTD PMID:10496880 NCBI chr  X:70,421,599...70,447,109
Ensembl chr  X:70,426,951...70,428,364
JBrowse link
G Pon2 paraoxonase 2 increases response to substance ISO PON2 protein results in increased susceptibility to N-(3-oxododecanoyl)homoserine lactone CTD PMID:25627690 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        molecular messenger 18307
          signalling molecule 8269
            autoinducer 5
              (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol 0
              N-acyl homoserine lactone + 5
              autoinducer-2 0
paths to the root