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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:71338 term browser browse the term
Definition:A signalling molecule produced and used by bacteria participating in quorum sensing, that is, in cell-cell communication to coordinate community-wide regulation of processes such as biofilm formation, virulence, and bioluminescence in populations of bacteria. Such communication can occur both within and between different species of bacteria.
Synonyms:related_synonym: autoinducers
 xref: Wikipedia:Autoinducer

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N-(3-oxododecanoyl)homoserine lactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity EXP N-(3-oxododecanoyl)homoserine lactone results in increased activity of CASP3 protein CTD PMID:25627690 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp7 caspase 7 increases activity EXP N-(3-oxododecanoyl)homoserine lactone results in increased activity of CASP7 protein CTD PMID:25627690 NCBI chr19:56,396,833...56,442,348
Ensembl chr19:56,397,129...56,442,344
JBrowse link
G P2ry2 purinergic receptor P2Y, G-protein coupled 2 multiple interactions
decreases expression
ISO Ibuprofen inhibits the reaction [N-(3-oxododecanoyl)homoserine lactone results in decreased expression of P2RY2 mRNA] CTD PMID:10496880 NCBI chr 7:100,996,568...101,012,053
Ensembl chr 7:100,996,568...101,012,866
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 decreases expression ISO N-(3-oxododecanoyl)homoserine lactone results in decreased expression of P2RY4 mRNA CTD PMID:10496880 NCBI chr  X:100,588,358...100,594,927
Ensembl chr  X:100,590,154...100,594,869
JBrowse link
G Pon2 paraoxonase 2 increases response to substance ISO PON2 protein results in increased susceptibility to N-(3-oxododecanoyl)homoserine lactone CTD PMID:25627690 NCBI chr 6:5,264,620...5,298,345
Ensembl chr 6:5,264,147...5,298,455
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 21552
    role 21530
      biological role 21528
        molecular messenger 18821
          signalling molecule 8449
            autoinducer 5
              (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol 0
              N-acyl homoserine lactone + 5
              autoinducer-2 0
paths to the root