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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dihydrochalcone
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Accession:CHEBI:71231 term browser browse the term
Definition:A member of the class of dihydrochalcones that is acetophenone in which one of the hydrogens of the methyl group is replaced by a benzyl group.
Synonyms:exact_synonym: 1,3-diphenylpropan-1-one
 related_synonym: 1,3-Diphenyl-1-oxopropane;   Formula=C15H14O;   Hydrochalcone;   Hydrocinnamophenone;   InChI=1S/C15H14O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-10H,11-12H2;   InChIKey=QGGZBXOADPVUPN-UHFFFAOYSA-N;   SMILES=O=C(CCc1ccccc1)c1ccccc1;   benzyl acetophenone;   beta-phenylpropiophenone
 xref: CAS:1083-30-3;   Reaxys:1910661;   Wikipedia:Dihydrochalcone


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phloretin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFP alpha fetoprotein affects binding ISO Phloretin binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AQP9 aquaporin 9 multiple interactions
decreases activity
ISO
EXP
Phloretin inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]
Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Selenic Acid analog]; Phloretin inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid]
Phloretin results in decreased activity of AQP9 protein
CTD PMID:9733774 PMID:12606488 PMID:21259319 PMID:28798983 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:24707119 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein] CTD PMID:24707119 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions ISO Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CSF3 colony stimulating factor 3 multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] CTD PMID:24707119 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] CTD PMID:17177569 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Phloretin binds to and results in increased activity of ESR1 protein CTD PMID:9751507 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions
affects binding
EXP Phloretin binds to and results in increased activity of ESR2 protein
Phloretin binds to ESR2 protein
CTD PMID:9751507 PMID:12224631 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO Phloretin inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:30287234 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases activity EXP Phloretin results in decreased activity of GSK3B protein CTD PMID:16968061 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,323...120,094,417
Ensembl chr 3:119,821,323...120,094,417
Ensembl chr 3:119,821,323...120,094,417
JBrowse link
G IFNG interferon gamma multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein] CTD PMID:24707119 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein] CTD PMID:24707119 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:24707119 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP Phloretin inhibits the reaction [Uric Acid results in increased secretion of IL1B protein] CTD PMID:21051542 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1RN protein] CTD PMID:24707119 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL6 interleukin 6 multiple interactions EXP Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:24707119 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS insulin multiple interactions EXP Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] CTD PMID:17965850 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,341
Ensembl chr11:2,159,779...2,161,341
JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 affects response to substance ISO KCNMA1 mRNA affects the susceptibility to Phloretin CTD PMID:19247476 NCBI chr10:76,869,602...77,637,969
Ensembl chr10:76,869,601...77,638,369
JBrowse link
G LTF lactotransferrin increases expression ISO Phloretin results in increased expression of LTF protein CTD PMID:24487097 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
JBrowse link
G NOS3 nitric oxide synthase 3 decreases expression
multiple interactions
EXP Phloretin results in decreased expression of NOS3 mRNA
Phloretin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]
CTD PMID:20021702 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G SHBG sex hormone binding globulin affects binding EXP Phloretin binds to SHBG protein CTD PMID:25349334 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382
JBrowse link
G SLC14A1 solute carrier family 14 member 1 (Kidd blood group) multiple interactions ISO Phloretin inhibits the reaction [SLC14A1 protein results in increased transport of Urea] CTD PMID:8982255 NCBI chr18:45,724,127...45,752,520
Ensembl chr18:45,687,025...45,752,520
JBrowse link
G SLC14A2 solute carrier family 14 member 2 multiple interactions ISO Phloretin inhibits the reaction [SLC14A2 protein results in increased transport of Urea] CTD PMID:11181411 NCBI chr18:45,167,963...45,683,688
Ensembl chr18:45,212,995...45,683,688
Ensembl chr18:45,212,995...45,683,688
JBrowse link
G SLC16A1 solute carrier family 16 member 1 multiple interactions ISO [[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate; [Phloretin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate CTD PMID:17108059 NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,013
Ensembl chr 1:112,911,847...112,957,013
JBrowse link
G SLC16A2 solute carrier family 16 member 2 multiple interactions EXP Phloretin inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:74,421,493...74,533,916
Ensembl chr  X:74,421,493...74,533,917
JBrowse link
G SLC2A1 solute carrier family 2 member 1 multiple interactions
decreases activity
EXP Phloretin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
Phloretin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC2A2 solute carrier family 2 member 2 multiple interactions
decreases expression
ISO
EXP
Phloretin inhibits the reaction [Fluorouracil promotes the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]]; Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose]
Phloretin results in decreased expression of SLC2A2 protein
Phloretin inhibits the reaction [SLC2A2 protein results in increased uptake of Glucose]
CTD PMID:15986457 PMID:17272349 PMID:26616219 NCBI chr 3:170,996,341...171,026,721
Ensembl chr 3:170,996,347...171,026,743
JBrowse link
G SLC2A9 solute carrier family 2 member 9 multiple interactions ISO Phloretin inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid] CTD PMID:19587147 NCBI chr 4:9,771,125...10,040,270
Ensembl chr 4:9,771,153...10,054,936
JBrowse link
G SLC9A1 solute carrier family 9 member A1 multiple interactions
decreases activity
EXP Phloretin inhibits the reaction [SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]]
Phloretin results in decreased activity of SLC9A1 protein; Phloretin results in decreased activity of SLC9A1 protein alternative form
CTD PMID:12765964 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
G SLC9B2 solute carrier family 9 member B2 decreases activity EXP Phloretin results in decreased activity of SLC9B2 protein CTD PMID:18000046 NCBI chr 4:103,018,029...103,077,319
Ensembl chr 4:103,019,868...103,085,829
JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 increases glucuronidation EXP UGT1A10 protein results in increased glucuronidation of Phloretin CTD PMID:14557274 NCBI chr 2:233,636,477...233,773,305
Ensembl chr 2:233,636,454...233,773,305
JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 increases glucuronidation EXP UGT1A7 protein results in increased glucuronidation of Phloretin CTD PMID:14557274 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,938...233,773,299
JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation EXP UGT1A8 protein results in increased glucuronidation of Phloretin CTD PMID:14557274 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,645...233,773,310
JBrowse link
phlorizin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase decreases expression ISO Phlorhizin results in decreased expression of ABAT mRNA CTD PMID:22538082 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575
JBrowse link
G ACAA1 acetyl-CoA acyltransferase 1 increases expression ISO Phlorhizin results in increased expression of ACAA1 mRNA CTD PMID:22538082 NCBI chr 3:38,122,710...38,137,127
Ensembl chr 3:38,103,129...38,137,242
JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 decreases expression ISO Phlorhizin results in decreased expression of ACAA2 mRNA CTD PMID:22538082 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
JBrowse link
G ACAD8 acyl-CoA dehydrogenase family member 8 decreases expression ISO Phlorhizin results in decreased expression of ACAD8 mRNA CTD PMID:22538082 NCBI chr11:134,253,538...134,265,858
Ensembl chr11:134,253,495...134,265,855
Ensembl chr11:134,253,495...134,265,855
JBrowse link
G ACAD9 acyl-CoA dehydrogenase family member 9 decreases expression ISO Phlorhizin results in decreased expression of ACAD9 mRNA CTD PMID:22538082 NCBI chr 3:128,879,596...128,913,114
Ensembl chr 3:128,879,596...128,916,067
Ensembl chr 3:128,879,596...128,916,067
JBrowse link
G ACADL acyl-CoA dehydrogenase long chain decreases expression ISO Phlorhizin results in decreased expression of ACADL mRNA CTD PMID:22538082 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447
JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain decreases expression ISO Phlorhizin results in decreased expression of ACADM mRNA CTD PMID:22538082 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,347...75,787,575
Ensembl chr 1:75,724,347...75,787,575
JBrowse link
G ACAT1 acetyl-CoA acetyltransferase 1 decreases expression ISO Phlorhizin results in decreased expression of ACAT1 mRNA CTD PMID:22538082 NCBI chr11:108,116,705...108,148,822
Ensembl chr11:108,116,695...108,147,603
JBrowse link
G ACO1 aconitase 1 decreases expression ISO Phlorhizin results in decreased expression of ACO1 mRNA CTD PMID:22538082 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACOX1 acyl-CoA oxidase 1 decreases expression ISO Phlorhizin results in decreased expression of ACOX1 mRNA CTD PMID:22538082 NCBI chr17:75,941,507...75,979,199
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G ACOX2 acyl-CoA oxidase 2 decreases expression ISO Phlorhizin results in decreased expression of ACOX2 mRNA CTD PMID:22538082 NCBI chr 3:58,505,136...58,537,196
Ensembl chr 3:58,505,136...58,537,283
JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 decreases expression ISO Phlorhizin results in decreased expression of ACSL1 mRNA CTD PMID:22538082 NCBI chr 4:184,755,595...184,826,593
Ensembl chr 4:184,755,595...184,826,818
JBrowse link
G ACTB actin beta increases expression ISO Phlorhizin results in increased expression of ACTB mRNA CTD PMID:22538082 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression ISO Phlorhizin results in decreased expression of ADH5 mRNA CTD PMID:22538082 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801
JBrowse link
G ADHFE1 alcohol dehydrogenase iron containing 1 decreases expression ISO Phlorhizin results in decreased expression of ADHFE1 mRNA CTD PMID:22538082 NCBI chr 8:66,432,504...66,468,907
Ensembl chr 8:66,432,492...66,468,907
JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 decreases expression ISO Phlorhizin results in decreased expression of AKR1A1 mRNA CTD PMID:22538082 NCBI chr 1:45,550,779...45,570,051
Ensembl chr 1:45,550,543...45,570,049
JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 increases expression ISO Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,303,965...19,312,146
Ensembl chr 1:19,303,965...19,312,146
JBrowse link
G ALB albumin multiple interactions EXP Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein] CTD PMID:16313995 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases expression
increases expression
ISO Phlorhizin results in decreased expression of ALDH2 mRNA
Phlorhizin results in increased expression of ALDH2 mRNA
CTD PMID:22538082 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 decreases expression ISO Phlorhizin results in decreased expression of ALDH3A2 mRNA CTD PMID:22538082 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760
JBrowse link
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH4A1 mRNA CTD PMID:22538082 NCBI chr 1:18,871,430...18,902,580
Ensembl chr 1:18,871,430...18,902,724
JBrowse link
G ALDH6A1 aldehyde dehydrogenase 6 family member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH6A1 mRNA CTD PMID:22538082 NCBI chr14:74,056,847...74,084,453
Ensembl chr14:74,056,847...74,084,492
JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 decreases expression ISO Phlorhizin results in decreased expression of ALDH7A1 mRNA CTD PMID:22538082 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362
JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 decreases expression ISO Phlorhizin results in decreased expression of ANAPC2 mRNA CTD PMID:22538082 NCBI chr 9:137,174,784...137,188,585
Ensembl chr 9:137,174,784...137,188,560
JBrowse link
G ANAPC5 anaphase promoting complex subunit 5 decreases expression ISO Phlorhizin results in decreased expression of ANAPC5 mRNA CTD PMID:22538082 NCBI chr12:121,308,245...121,354,209
Ensembl chr12:121,308,245...121,399,896
JBrowse link
G AOX1 aldehyde oxidase 1 decreases expression ISO Phlorhizin results in decreased expression of AOX1 mRNA CTD PMID:22538082 NCBI chr 2:200,585,952...200,677,064
Ensembl chr 2:200,586,014...200,677,064
JBrowse link
G AOX3P aldehyde oxidase 3, pseudogene decreases expression ISO Phlorhizin results in decreased expression of AOX3 mRNA CTD PMID:22538082 NCBI chr 2:200,695,723...200,738,781
Ensembl chr 2:200,678,233...200,734,109
JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit increases expression ISO Phlorhizin results in increased expression of APH1B mRNA CTD PMID:22538082 NCBI chr15:63,277,550...63,309,126
Ensembl chr15:63,276,018...63,309,126
JBrowse link
G APP amyloid beta precursor protein decreases expression ISO Phlorhizin results in decreased expression of APP mRNA CTD PMID:22538082 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ATF3 activating transcription factor 3 decreases expression ISO Phlorhizin results in decreased expression of ATF3 mRNA CTD PMID:16123366 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO Phlorhizin results in increased expression of ATP2A2 mRNA CTD PMID:16123366 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha decreases expression ISO Phlorhizin results in decreased expression of ATP5A1 mRNA CTD PMID:22538082 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334
JBrowse link
G ATP5F1C ATP synthase F1 subunit gamma increases expression ISO Phlorhizin results in increased expression of ATP5C1 mRNA CTD PMID:22538082 NCBI chr10:7,788,159...7,807,801
Ensembl chr10:7,788,147...7,807,815
JBrowse link
G AUH AU RNA binding methylglutaconyl-CoA hydratase decreases expression ISO Phlorhizin results in decreased expression of AUH mRNA CTD PMID:22538082 NCBI chr 9:91,213,823...91,361,945
Ensembl chr 9:91,213,815...91,361,913
Ensembl chr 9:91,213,815...91,361,913
JBrowse link
G B2M beta-2-microglobulin increases expression ISO Phlorhizin results in increased expression of B2M mRNA CTD PMID:22538082 NCBI chr15:44,711,492...44,718,145
Ensembl chr15:44,711,487...44,718,877
Ensembl chr15:44,711,487...44,718,877
JBrowse link
G BAG1 BAG cochaperone 1 decreases expression ISO Phlorhizin results in decreased expression of BAG1 mRNA CTD PMID:22538082 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720
JBrowse link
G BCKDHB branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO Phlorhizin results in decreased expression of BCKDHB mRNA CTD PMID:22538082 NCBI chr 6:80,106,610...80,469,088
Ensembl chr 6:80,106,647...80,346,270
JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 increases expression ISO Phlorhizin results in increased expression of BIRC6 mRNA CTD PMID:22538082 NCBI chr 2:32,356,907...32,618,899
Ensembl chr 2:32,357,028...32,618,899
JBrowse link
G CAT catalase increases expression ISO Phlorhizin results in increased expression of CAT mRNA CTD PMID:22538082 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 decreases expression ISO Phlorhizin results in decreased expression of CCT7 mRNA CTD PMID:22538082 NCBI chr 2:73,233,425...73,253,008
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] CTD PMID:18715473 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,669...137,020,255
Ensembl chr 7:136,868,669...137,020,255
JBrowse link
G CLYBL citramalyl-CoA lyase decreases expression ISO Phlorhizin results in decreased expression of CLYBL mRNA CTD PMID:22538082 NCBI chr13:99,606,664...99,909,444
Ensembl chr13:99,606,669...99,897,134
JBrowse link
G COX15 cytochrome c oxidase assembly homolog COX15 decreases expression ISO Phlorhizin results in decreased expression of COX15 mRNA CTD PMID:22538082 NCBI chr10:99,694,293...99,732,131
Ensembl chr10:99,711,844...99,732,100
Ensembl chr10:99,711,844...99,732,100
JBrowse link
G COX17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO Phlorhizin results in decreased expression of COX17 mRNA CTD PMID:22538082 NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454
JBrowse link
G COX7C cytochrome c oxidase subunit 7C increases expression ISO Phlorhizin results in increased expression of COX7C mRNA CTD PMID:22538082 NCBI chr 5:86,617,941...86,620,962
Ensembl chr 5:86,617,928...86,620,962
JBrowse link
G COX8A cytochrome c oxidase subunit 8A decreases expression ISO Phlorhizin results in decreased expression of COX8A mRNA CTD PMID:22538082 NCBI chr11:63,974,620...63,976,543
Ensembl chr11:63,974,620...63,976,543
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A decreases expression ISO Phlorhizin results in decreased expression of CPT1A mRNA CTD PMID:16123366 PMID:22538082 NCBI chr11:68,754,620...68,844,410
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CPT2 carnitine palmitoyltransferase 2 decreases expression ISO Phlorhizin results in decreased expression of CPT2 mRNA CTD PMID:22538082 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
JBrowse link
G CREBBP CREB binding protein decreases expression ISO Phlorhizin results in decreased expression of CREBBP mRNA CTD PMID:22538082 NCBI chr16:3,725,054...3,880,727
Ensembl chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CS citrate synthase decreases expression ISO Phlorhizin results in decreased expression of CS mRNA CTD PMID:22538082 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
JBrowse link
G CUL1 cullin 1 decreases expression ISO Phlorhizin results in decreased expression of CUL1 mRNA CTD PMID:22538082 NCBI chr 7:148,697,756...148,801,110
Ensembl chr 7:148,697,914...148,801,110
JBrowse link
G CYB5R3 cytochrome b5 reductase 3 decreases expression ISO Phlorhizin results in decreased expression of CYB5R3 mRNA CTD PMID:22538082 NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,617,840...42,649,392
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases expression ISO Phlorhizin results in decreased expression of CYP1A2 mRNA CTD PMID:22538082 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 decreases expression ISO Phlorhizin results in decreased expression of CYP2B6 mRNA CTD PMID:22538082 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 increases expression ISO Phlorhizin results in increased expression of CYP2D6 mRNA CTD PMID:22538082 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,881
Ensembl chr22:42,126,499...42,130,881
JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 decreases expression ISO Phlorhizin results in decreased expression of CYP4F12 mRNA CTD PMID:22538082 NCBI chr19:15,673,023...15,698,819
Ensembl chr19:15,673,018...15,697,174
JBrowse link
G DHRS4 dehydrogenase/reductase 4 decreases expression ISO Phlorhizin results in decreased expression of DHRS4 mRNA CTD PMID:22538082 NCBI chr14:23,953,735...23,969,279
Ensembl chr14:23,953,734...23,969,279
JBrowse link
G DLD dihydrolipoamide dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of DLD mRNA CTD PMID:22538082 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730
JBrowse link
G DNAJA2 DnaJ heat shock protein family (Hsp40) member A2 decreases expression ISO Phlorhizin results in decreased expression of DNAJA2 mRNA CTD PMID:22538082 NCBI chr16:46,955,362...46,973,674
Ensembl chr16:46,955,362...46,973,674
JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 decreases expression ISO Phlorhizin results in decreased expression of DNAJA3 mRNA CTD PMID:22538082 NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of DNAJB1 mRNA
Phlorhizin results in increased expression of DNAJB1 mRNA
CTD PMID:22538082 NCBI chr19:14,514,769...14,530,597
Ensembl chr19:14,514,769...14,529,770
Ensembl chr19:14,514,769...14,529,770
JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 decreases expression ISO Phlorhizin results in decreased expression of DNAJB4 mRNA CTD PMID:22538082 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO Phlorhizin results in increased expression of DNAJB6 mRNA CTD PMID:22538082 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439
JBrowse link
G DNAJC1 DnaJ heat shock protein family (Hsp40) member C1 decreases expression ISO Phlorhizin results in decreased expression of DNAJC1 mRNA CTD PMID:22538082 NCBI chr10:21,756,548...22,003,763
Ensembl chr10:21,756,548...22,003,769
JBrowse link
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 decreases expression ISO Phlorhizin results in decreased expression of DNAJC13 mRNA CTD PMID:22538082 NCBI chr 3:132,417,502...132,539,032
Ensembl chr 3:132,417,502...132,539,032
JBrowse link
G DNAJC14 DnaJ heat shock protein family (Hsp40) member C14 increases expression ISO Phlorhizin results in increased expression of DNAJC14 mRNA CTD PMID:22538082 NCBI chr12:55,820,985...55,829,587
Ensembl chr12:55,820,960...55,830,824
JBrowse link
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Phlorhizin results in decreased expression of DNAJC19 mRNA CTD PMID:22538082 NCBI chr 3:180,983,709...180,989,838
Ensembl chr 3:180,983,709...180,989,774
JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Phlorhizin results in decreased expression of DNAJC3 mRNA CTD PMID:22538082 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DNAJC4 DnaJ heat shock protein family (Hsp40) member C4 increases expression ISO Phlorhizin results in increased expression of DNAJC4 mRNA CTD PMID:22538082 NCBI chr11:64,230,432...64,234,281
Ensembl chr11:64,230,278...64,234,286
JBrowse link
G DNAJC5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression ISO Phlorhizin results in decreased expression of DNAJC5 mRNA CTD PMID:22538082 NCBI chr20:63,895,126...63,936,026
Ensembl chr20:63,895,126...63,936,031
JBrowse link
G ECHS1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Phlorhizin results in decreased expression of ECHS1 mRNA CTD PMID:22538082 NCBI chr10:133,362,480...133,373,396
Ensembl chr10:133,362,485...133,373,354
JBrowse link
G EP300 E1A binding protein p300 decreases expression ISO Phlorhizin results in decreased expression of EP300 mRNA CTD PMID:22538082 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G EPHX1 epoxide hydrolase 1 decreases expression ISO Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,092...225,845,563
Ensembl chr 1:225,810,092...225,845,563
JBrowse link
G FAS Fas cell surface death receptor decreases expression ISO Phlorhizin results in decreased expression of FAS mRNA CTD PMID:16123366 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 decreases expression ISO Phlorhizin results in decreased expression of FBXW7 mRNA CTD PMID:22538082 NCBI chr 4:152,320,544...152,536,873
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FH fumarate hydratase decreases expression ISO Phlorhizin results in decreased expression of FH mRNA CTD PMID:22538082 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,603...241,519,761
Ensembl chr 1:241,497,603...241,519,761
JBrowse link
G FIS1 fission, mitochondrial 1 increases expression ISO Phlorhizin results in increased expression of FIS1 mRNA CTD PMID:22538082 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FKBP5 FKBP prolyl isomerase 5 decreases expression ISO Phlorhizin results in decreased expression of FKBP5 mRNA CTD PMID:22538082 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583
JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Phlorhizin results in decreased expression of FMO1 mRNA CTD PMID:22538082 NCBI chr 1:171,248,473...171,285,978
Ensembl chr 1:171,248,471...171,285,978
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA] CTD PMID:12446591 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases expression ISO Phlorhizin results in decreased expression of GCLC mRNA CTD PMID:22538082 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit decreases expression ISO Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GLRX2 glutaredoxin 2 decreases expression ISO Phlorhizin results in decreased expression of GLRX2 mRNA CTD PMID:22538082 NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114
JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 increases expression
decreases expression
ISO Phlorhizin results in increased expression of GPD2 mRNA
Phlorhizin results in decreased expression of GPD2 mRNA
CTD PMID:16123366 PMID:22538082 NCBI chr 2:156,435,290...156,586,403
Ensembl chr 2:156,435,290...156,613,735
JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression ISO Phlorhizin results in decreased expression of GPX1 mRNA CTD PMID:16123366 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GPX7 glutathione peroxidase 7 increases expression ISO Phlorhizin results in increased expression of GPX7 mRNA CTD PMID:22538082 NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051
JBrowse link
G GSTA5 glutathione S-transferase alpha 5 decreases expression ISO Phlorhizin results in decreased expression of GSTA5 mRNA CTD PMID:22538082 NCBI chr 6:52,831,742...52,846,095
Ensembl chr 6:52,831,655...52,846,095
Ensembl chr 6:52,831,655...52,846,095
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 decreases expression ISO Phlorhizin results in decreased expression of GSTK1 mRNA CTD PMID:22538082 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G GSTM1 glutathione S-transferase mu 1 decreases expression ISO Phlorhizin results in decreased expression of GSTM1 mRNA CTD PMID:22538082 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTM2 glutathione S-transferase mu 2 increases expression ISO Phlorhizin results in increased expression of GSTM2 mRNA CTD PMID:22538082 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTM4 glutathione S-transferase mu 4 increases expression ISO Phlorhizin results in increased expression of GSTM4 mRNA CTD PMID:22538082 NCBI chr 1:109,656,076...109,665,497
Ensembl chr 1:109,656,099...109,674,836
JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression ISO Phlorhizin results in increased expression of GSTP1 mRNA CTD PMID:22538082 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 decreases expression
increases expression
ISO Phlorhizin results in decreased expression of GSTT1 mRNA
Phlorhizin results in increased expression of GSTT1 mRNA
CTD PMID:22538082
G GSTT2B glutathione S-transferase theta 2B decreases expression ISO Phlorhizin results in decreased expression of GSTT2B mRNA CTD PMID:22538082 NCBI chr22:23,957,414...23,961,206
Ensembl chr22:23,957,414...23,961,195
Ensembl chr22:23,957,414...23,961,195
JBrowse link
G HACD3 3-hydroxyacyl-CoA dehydratase 3 decreases expression ISO Phlorhizin results in decreased expression of HACD3 mRNA CTD PMID:22538082 NCBI chr15:65,530,463...65,578,355
Ensembl chr15:65,530,418...65,578,349
JBrowse link
G HADHB hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Phlorhizin results in increased expression of HADHB mRNA CTD PMID:22538082 NCBI chr 2:26,244,917...26,290,465
Ensembl chr 2:26,243,170...26,290,465
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Phlorhizin results in decreased expression of HERPUD1 mRNA CTD PMID:22538082 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
JBrowse link
G HIBADH 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of HIBADH mRNA CTD PMID:22538082 NCBI chr 7:27,525,440...27,662,903
Ensembl chr 7:27,525,442...27,662,883
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Phlorhizin results in decreased expression of HMGCS1 mRNA CTD PMID:22538082 NCBI chr 5:43,287,470...43,313,477
Ensembl chr 5:43,287,470...43,313,512
JBrowse link
G HMOX1 heme oxygenase 1 decreases expression ISO Phlorhizin results in decreased expression of HMOX1 mRNA CTD PMID:16123366 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HRAS HRas proto-oncogene, GTPase increases expression ISO Phlorhizin results in increased expression of HRAS mRNA CTD PMID:22538082 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 decreases expression ISO Phlorhizin results in decreased expression of HSD17B10 mRNA CTD PMID:22538082 NCBI chr  X:53,431,258...53,434,376
Ensembl chr  X:53,431,258...53,434,370
Ensembl chr  X:53,431,258...53,434,370
JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 decreases expression ISO Phlorhizin results in decreased expression of HSD17B4 mRNA CTD PMID:22538082 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,473...119,637,199
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Phlorhizin results in decreased expression of HSP90AA1 mRNA CTD PMID:22538082 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Phlorhizin results in decreased expression of HSP90AB1 mRNA CTD PMID:22538082 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G HSPA13 heat shock protein family A (Hsp70) member 13 decreases expression ISO Phlorhizin results in decreased expression of HSPA13 mRNA CTD PMID:22538082 NCBI chr21:14,371,115...14,383,146
Ensembl chr21:14,371,115...14,383,484
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression ISO Phlorhizin results in increased expression of HSPA5 mRNA CTD PMID:22538082 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 increases expression ISO Phlorhizin results in increased expression of HSPA8 mRNA CTD PMID:22538082 NCBI chr11:123,057,489...123,062,366
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Phlorhizin results in decreased expression of HSPA9 mRNA CTD PMID:22538082 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression ISO Phlorhizin results in increased expression of HSPB1 mRNA CTD PMID:22538082 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HSPB8 heat shock protein family B (small) member 8 decreases expression ISO Phlorhizin results in decreased expression of HSPB8 mRNA CTD PMID:22538082 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
Ensembl chr12:119,171,555...119,224,855
Ensembl chr12:119,171,555...119,224,855
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Phlorhizin results in decreased expression of HSPD1 mRNA CTD PMID:22538082 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 decreases expression ISO Phlorhizin results in decreased expression of HSPE1 mRNA CTD PMID:22538082 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449
JBrowse link
G HTRA2 HtrA serine peptidase 2 decreases expression ISO Phlorhizin results in decreased expression of HTRA2 mRNA CTD PMID:22538082 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,725...74,533,332
Ensembl chr 2:74,529,725...74,533,332
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein decreases expression ISO Phlorhizin results in decreased expression of ID1 mRNA CTD PMID:16123366 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Phlorhizin results in increased expression of IDH2 mRNA CTD PMID:22538082 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,504
Ensembl chr15:90,083,045...90,102,504
JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO Phlorhizin results in decreased expression of IDH3A mRNA CTD PMID:22538082 NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
JBrowse link
G IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta decreases expression ISO Phlorhizin results in decreased expression of IDH3B mRNA CTD PMID:22538082 NCBI chr20:2,658,394...2,664,216
Ensembl chr20:2,658,395...2,664,219
JBrowse link
G IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma decreases expression ISO Phlorhizin results in decreased expression of IDH3G mRNA CTD PMID:22538082 NCBI chr  X:153,785,768...153,794,375
Ensembl chr  X:153,785,766...153,794,523
JBrowse link
G IVD isovaleryl-CoA dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of IVD mRNA CTD PMID:22538082 NCBI chr15:40,405,787...40,435,948
Ensembl chr15:40,405,485...40,435,947
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Phlorhizin results in decreased expression of JUNB mRNA CTD PMID:22538082 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Phlorhizin results in increased expression of JUND mRNA CTD PMID:22538082 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 increases expression ISO Phlorhizin results in increased expression of KCNJ11 mRNA CTD PMID:16123366 NCBI chr11:17,385,246...17,389,346
Ensembl chr11:17,385,859...17,389,331
Ensembl chr11:17,385,859...17,389,331
JBrowse link
G KEAP1 kelch like ECH associated protein 1 increases expression ISO Phlorhizin results in increased expression of KEAP1 mRNA CTD PMID:22538082 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KRAS KRAS proto-oncogene, GTPase decreases expression ISO Phlorhizin results in decreased expression of KRAS mRNA CTD PMID:22538082 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G MAF MAF bZIP transcription factor decreases expression ISO Phlorhizin results in decreased expression of MAF mRNA CTD PMID:22538082 NCBI chr16:79,202,624...79,601,952
Ensembl chr16:79,585,843...79,600,737
JBrowse link
G MAFG MAF bZIP transcription factor G decreases expression ISO Phlorhizin results in decreased expression of MAFG mRNA CTD PMID:22538082 NCBI chr17:81,918,270...81,927,735
Ensembl chr17:81,918,270...81,927,735
JBrowse link
G MAOB monoamine oxidase B decreases expression ISO Phlorhizin results in decreased expression of MAOB mRNA CTD PMID:22538082 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 increases expression ISO Phlorhizin results in increased expression of MAP2K2 mRNA CTD PMID:22538082 NCBI chr19:4,090,321...4,124,184
Ensembl chr19:4,090,321...4,124,129
Ensembl chr19:4,090,321...4,124,129
JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 increases expression ISO Phlorhizin results in increased expression of MAP2K6 mRNA CTD PMID:22538082 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 increases expression ISO Phlorhizin results in increased expression of MAP2K7 mRNA CTD PMID:22538082 NCBI chr19:7,903,785...7,914,478
Ensembl chr19:7,903,843...7,914,478
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 decreases expression ISO Phlorhizin results in decreased expression of MAP3K7 mRNA CTD PMID:22538082 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,072
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases expression ISO Phlorhizin results in increased expression of MAPK3 mRNA CTD PMID:22538082 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 decreases expression ISO Phlorhizin results in decreased expression of MAPK9 mRNA CTD PMID:22538082 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MCCC2 methylcrotonoyl-CoA carboxylase 2 decreases expression ISO Phlorhizin results in decreased expression of MCCC2 mRNA CTD PMID:22538082 NCBI chr 5:71,587,340...71,658,706
Ensembl chr 5:71,587,288...71,658,706
JBrowse link
G MDM2 MDM2 proto-oncogene decreases expression ISO Phlorhizin results in decreased expression of MDM2 mRNA CTD PMID:22538082 NCBI chr12:68,808,149...68,850,686
Ensembl chr12:68,808,177...68,850,686
JBrowse link
G MED20 mediator complex subunit 20 decreases expression ISO Phlorhizin results in decreased expression of MED20 mRNA CTD PMID:22538082 NCBI chr 6:41,905,354...41,921,139
Ensembl chr 6:41,905,354...41,921,139
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression ISO Phlorhizin results in increased expression of MGST1 mRNA CTD PMID:22538082 NCBI chr12:16,347,115...16,377,192
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MMUT methylmalonyl-CoA mutase decreases expression ISO Phlorhizin results in decreased expression of MMUT mRNA CTD PMID:22538082 NCBI chr 6:49,430,360...49,463,298
Ensembl chr 6:49,430,360...49,463,253
JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation ISO Phlorhizin results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr20:36,541,519...36,551,447
Ensembl chr20:36,541,497...36,551,447
JBrowse link
G NDUFA12 NADH:ubiquinone oxidoreductase subunit A12 increases expression ISO Phlorhizin results in increased expression of NDUFA12 mRNA CTD PMID:22538082 NCBI chr12:94,971,333...95,003,697
Ensembl chr12:94,897,055...95,003,748
JBrowse link
G NDUFA2 NADH:ubiquinone oxidoreductase subunit A2 increases expression ISO Phlorhizin results in increased expression of NDUFA2 mRNA CTD PMID:22538082 NCBI chr 5:140,645,285...140,647,630
Ensembl chr 5:140,638,740...140,647,785
Ensembl chr 5:140,638,740...140,647,785
JBrowse link
G NDUFA3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression ISO Phlorhizin results in decreased expression of NDUFA3 mRNA CTD PMID:22538082 NCBI chr19:54,102,338...54,107,568
Ensembl chr19:54,102,728...54,109,257
JBrowse link
G NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 increases expression ISO Phlorhizin results in increased expression of NDUFA7 mRNA CTD PMID:22538082 NCBI chr19:8,308,595...8,321,375
Ensembl chr19:8,308,768...8,321,375
JBrowse link
G NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression ISO Phlorhizin results in increased expression of NDUFAB1 mRNA CTD PMID:22538082 NCBI chr16:23,581,012...23,596,329
Ensembl chr16:23,581,014...23,596,316
JBrowse link
G NDUFAF1 NADH:ubiquinone oxidoreductase complex assembly factor 1 decreases expression ISO Phlorhizin results in decreased expression of NDUFAF1 mRNA CTD PMID:22538082 NCBI chr15:41,387,353...41,402,501
Ensembl chr15:41,387,353...41,402,519
Ensembl chr15:41,387,353...41,402,519
JBrowse link
G NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO Phlorhizin results in decreased expression of NDUFB6 mRNA CTD PMID:22538082 NCBI chr 9:32,553,001...32,573,159
Ensembl chr 9:32,553,001...32,573,184
JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 decreases expression ISO Phlorhizin results in decreased expression of NDUFS1 mRNA CTD PMID:22538082 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509
JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO Phlorhizin results in decreased expression of NDUFS4 mRNA CTD PMID:22538082 NCBI chr 5:53,560,610...53,683,338
Ensembl chr 5:53,560,633...53,683,338
JBrowse link
G NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 decreases expression ISO Phlorhizin results in decreased expression of NDUFS5 mRNA CTD PMID:22538082 NCBI chr 1:39,026,350...39,034,615
Ensembl chr 1:39,026,318...39,034,636
JBrowse link
G NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 increases expression ISO Phlorhizin results in increased expression of NDUFS8 mRNA CTD PMID:22538082 NCBI chr11:68,030,681...68,036,644
Ensembl chr11:68,030,617...68,036,644
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Phlorhizin results in decreased expression of NEDD4 mRNA CTD PMID:22538082 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,746
Ensembl chr15:55,826,922...55,993,746
JBrowse link
G NEUROD1 neuronal differentiation 1 increases expression ISO Phlorhizin results in increased expression of NEUROD1 mRNA CTD PMID:16123366 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,673,088...181,680,547
Ensembl chr 2:181,673,088...181,680,547
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 decreases expression ISO Phlorhizin results in decreased expression of NFE2L2 mRNA CTD PMID:22538082 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NKX6-1 NK6 homeobox 1 increases expression ISO Phlorhizin results in increased expression of NKX6-1 mRNA CTD PMID:16123366 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,987...84,498,450
Ensembl chr 4:84,491,987...84,498,450
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
decreases expression
EXP Phlorhizin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA]
Phlorhizin results in decreased expression of NOS3 mRNA
CTD PMID:20021702 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NRAS NRAS proto-oncogene, GTPase decreases expression ISO Phlorhizin results in decreased expression of NRAS mRNA CTD PMID:22538082 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G OGDH oxoglutarate dehydrogenase decreases expression ISO Phlorhizin results in decreased expression of OGDH mRNA CTD PMID:22538082 NCBI chr 7:44,606,572...44,709,066
Ensembl chr 7:44,606,572...44,709,066
JBrowse link
G PARK7 Parkinsonism associated deglycase increases expression ISO Phlorhizin results in increased expression of PARK7 mRNA CTD PMID:22538082 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PC pyruvate carboxylase increases expression
decreases expression
ISO Phlorhizin results in increased expression of PCX mRNA
Phlorhizin results in decreased expression of PC mRNA
CTD PMID:16123366 PMID:22538082 NCBI chr11:66,848,420...66,958,418
Ensembl chr11:66,848,417...66,958,386
JBrowse link
G PCCA propionyl-CoA carboxylase subunit alpha decreases expression ISO Phlorhizin results in decreased expression of PCCA mRNA CTD PMID:22538082 NCBI chr13:100,089,020...100,530,435
Ensembl chr13:100,089,015...100,530,437
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Phlorhizin results in decreased expression of PCK1 mRNA CTD PMID:22538082 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
JBrowse link
G PECR peroxisomal trans-2-enoyl-CoA reductase increases expression
decreases expression
ISO Phlorhizin results in increased expression of PECR mRNA
Phlorhizin results in decreased expression of PECR mRNA
CTD PMID:22538082 NCBI chr 2:216,031,656...216,081,843
Ensembl chr 2:215,996,329...216,082,955
JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha decreases expression ISO Phlorhizin results in decreased expression of PIK3C2A mRNA CTD PMID:22538082 NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,983
JBrowse link
G PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 decreases expression ISO Phlorhizin results in decreased expression of PIK3C3 mRNA CTD PMID:22538082 NCBI chr18:41,955,226...42,087,830
Ensembl chr18:41,955,234...42,087,830
JBrowse link
G PINK1 PTEN induced kinase 1 increases expression ISO Phlorhizin results in increased expression of PINK1 mRNA CTD PMID:22538082 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G PRDX1 peroxiredoxin 1 increases expression ISO Phlorhizin results in increased expression of PRDX1 mRNA CTD PMID:22538082 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,511,036...45,523,047
Ensembl chr 1:45,511,036...45,523,047
JBrowse link
G PRDX5 peroxiredoxin 5 decreases expression ISO Phlorhizin results in decreased expression of PRDX5 mRNA CTD PMID:22538082 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
JBrowse link
G PRKCH protein kinase C eta increases expression ISO Phlorhizin results in increased expression of PRKCH mRNA CTD PMID:22538082 NCBI chr14:61,187,305...61,550,980
Ensembl chr14:61,187,559...61,550,976
JBrowse link
G PRKCI protein kinase C iota decreases expression ISO Phlorhizin results in decreased expression of PRKCI mRNA CTD PMID:22538082 NCBI chr 3:170,222,424...170,305,981
Ensembl chr 3:170,222,424...170,305,977
JBrowse link
G PRKD3 protein kinase D3 decreases expression ISO Phlorhizin results in decreased expression of PRKD3 mRNA CTD PMID:22538082 NCBI chr 2:37,250,502...37,324,833
Ensembl chr 2:37,250,502...37,324,833
Ensembl chr 2:37,250,502...37,324,833
JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 decreases expression ISO Phlorhizin results in decreased expression of PSMA4 mRNA CTD PMID:22538082 NCBI chr15:78,540,405...78,552,417
Ensembl chr15:78,540,405...78,552,417
JBrowse link
G PSMB1 proteasome 20S subunit beta 1 increases expression ISO Phlorhizin results in increased expression of PSMB1 mRNA CTD PMID:22538082 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 decreases expression ISO Phlorhizin results in decreased expression of PSMB2 mRNA CTD PMID:22538082 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 decreases expression ISO Phlorhizin results in decreased expression of PSMC1 mRNA CTD PMID:22538082 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 increases expression
decreases expression
ISO Phlorhizin results in increased expression of PSMC4 mRNA
Phlorhizin results in decreased expression of PSMC4 mRNA
CTD PMID:22538082 NCBI chr19:39,971,150...39,981,764
Ensembl chr19:39,971,165...39,981,764
JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 decreases expression ISO Phlorhizin results in decreased expression of PSMC6 mRNA CTD PMID:22538082 NCBI chr14:52,707,163...52,728,590
Ensembl chr14:52,707,178...52,728,590
JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 decreases expression ISO Phlorhizin results in decreased expression of PSMD10 mRNA CTD PMID:22538082 NCBI chr  X:108,084,207...108,091,542
Ensembl chr  X:108,084,207...108,091,549
JBrowse link
G PSMD12 proteasome 26S subunit, non-ATPase 12 decreases expression ISO Phlorhizin results in decreased expression of PSMD12 mRNA CTD PMID:22538082 NCBI chr17:67,337,916...67,366,598
Ensembl chr17:67,337,916...67,366,605
JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 decreases expression ISO Phlorhizin results in decreased expression of PSMD14 mRNA CTD PMID:22538082 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717
JBrowse link
G PSMD4 proteasome 26S subunit, non-ATPase 4 decreases expression ISO Phlorhizin results in decreased expression of PSMD4 mRNA CTD PMID:22538082 NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,703...151,267,479
Ensembl chr 1:151,254,703...151,267,479
JBrowse link
G PSMD6 proteasome 26S subunit, non-ATPase 6 increases expression ISO Phlorhizin results in increased expression of PSMD6 mRNA CTD PMID:22538082 NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010
Ensembl chr 3:64,010,550...64,024,010
JBrowse link
G PSMD7 proteasome 26S subunit, non-ATPase 7 decreases expression ISO Phlorhizin results in decreased expression of PSMD7 mRNA CTD PMID:22538082 NCBI chr16:74,296,814...74,306,288
Ensembl chr16:74,296,814...74,306,288
JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 decreases expression ISO Phlorhizin results in decreased expression of PSMD9 mRNA CTD PMID:22538082 NCBI chr12:121,888,790...121,918,297
Ensembl chr12:121,888,809...121,921,470
Ensembl chr12:121,888,809...121,921,470
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression ISO Phlorhizin results in decreased expression of RAF1 mRNA CTD PMID:22538082 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,583,601...12,664,226
Ensembl chr 3:12,583,601...12,664,226
JBrowse link
G RDH14 retinol dehydrogenase 14 increases expression ISO Phlorhizin results in increased expression of RDH14 mRNA CTD PMID:22538082 NCBI chr 2:18,554,723...18,560,653
Ensembl chr 2:18,554,723...18,560,679
JBrowse link
G S100A6 S100 calcium binding protein A6 decreases expression ISO Phlorhizin results in decreased expression of S100A6 mRNA CTD PMID:16123366 NCBI chr 1:153,534,599...153,536,049
Ensembl chr 1:153,534,599...153,536,244
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A decreases expression ISO Phlorhizin results in decreased expression of SDHA mRNA CTD PMID:22538082 NCBI chr 5:218,309...264,816
Ensembl chr 5:218,241...257,082
JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B increases expression ISO Phlorhizin results in increased expression of SDHB mRNA CTD PMID:22538082 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,722...17,054,032
JBrowse link
G SDS serine dehydratase decreases expression ISO Phlorhizin results in decreased expression of SDS mRNA CTD PMID:22538082 NCBI chr12:113,392,445...113,403,887
Ensembl chr12:113,392,445...113,426,301
JBrowse link
G SLC2A2 solute carrier family 2 member 2 increases expression ISO Phlorhizin results in increased expression of SLC2A2 mRNA CTD PMID:16123366 NCBI chr 3:170,996,341...171,026,721
Ensembl chr 3:170,996,347...171,026,743
JBrowse link
G SLC35A2 solute carrier family 35 member A2 increases expression ISO Phlorhizin results in increased expression of SLC35A2 mRNA CTD PMID:22538082 NCBI chr  X:48,903,183...48,911,958
Ensembl chr  X:48,903,180...48,911,958
JBrowse link
G SLC5A1 solute carrier family 5 member 1 multiple interactions
decreases activity
affects binding
EXP
ISO
Phlorhizin inhibits the reaction [[Sodium co-treated with SLC5A1 protein] results in increased uptake of methylglucoside]; Phlorhizin inhibits the reaction [SLC5A1 protein results in increased uptake of methylglucoside]
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of spiraeoside
[Phlorhizin results in decreased activity of SLC5A1 protein] which results in decreased uptake of Glucose
SLC5A1 protein binds to Phlorhizin
CTD PMID:12663055 PMID:12927799 PMID:16300400 PMID:17288452 PMID:17983207 NCBI chr22:32,043,050...32,113,029
Ensembl chr22:32,043,261...32,113,029
JBrowse link
G SLC5A2 solute carrier family 5 member 2 decreases activity EXP Phlorhizin results in decreased activity of SLC5A2 protein CTD PMID:21128592 NCBI chr16:31,482,535...31,490,769
Ensembl chr16:31,483,002...31,490,860
JBrowse link
G SOD1 superoxide dismutase 1 increases expression ISO Phlorhizin results in increased expression of SOD1 mRNA CTD PMID:22538082 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,622...31,668,931
Ensembl chr21:31,659,622...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 decreases expression ISO Phlorhizin results in decreased expression of SOD2 mRNA CTD PMID:22538082 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G STIP1 stress induced phosphoprotein 1 decreases expression ISO Phlorhizin results in decreased expression of STIP1 mRNA CTD PMID:22538082 NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,543
JBrowse link
G SUCLA2 succinate-CoA ligase ADP-forming subunit beta decreases expression ISO Phlorhizin results in decreased expression of SUCLA2 mRNA CTD PMID:22538082 NCBI chr13:47,942,656...48,001,273
Ensembl chr13:47,745,736...48,037,968
JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO Phlorhizin results in decreased expression of SUCLG2 mRNA CTD PMID:22538082 NCBI chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612
Ensembl chr 3:67,360,460...67,654,612
JBrowse link
G SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone decreases expression ISO Phlorhizin results in decreased expression of SUGT1 mRNA CTD PMID:22538082 NCBI chr13:52,652,703...52,700,909
Ensembl chr13:52,652,709...52,700,909
JBrowse link
G TXN thioredoxin decreases expression
increases expression
ISO Phlorhizin results in decreased expression of TXN mRNA
Phlorhizin results in increased expression of TXN mRNA
CTD PMID:22538082 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXN2 thioredoxin 2 increases expression ISO Phlorhizin results in increased expression of TXN2 mRNA CTD PMID:22538082 NCBI chr22:36,467,036...36,481,672
Ensembl chr22:36,467,046...36,481,640
JBrowse link
G UBB ubiquitin B increases expression ISO Phlorhizin results in increased expression of UBB mRNA CTD PMID:22538082 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G UBC ubiquitin C decreases expression ISO Phlorhizin results in decreased expression of UBC mRNA CTD PMID:22538082 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B decreases expression ISO Phlorhizin results in decreased expression of UBE2B mRNA CTD PMID:22538082 NCBI chr 5:134,371,569...134,392,108
Ensembl chr 5:134,371,469...134,392,108
JBrowse link
G UBE2F ubiquitin conjugating enzyme E2 F (putative) decreases expression ISO Phlorhizin results in decreased expression of UBE2F mRNA CTD PMID:22538082 NCBI chr 2:237,967,014...238,042,782
Ensembl chr 2:237,966,827...238,042,782
JBrowse link
G UBE2H ubiquitin conjugating enzyme E2 H decreases expression ISO Phlorhizin results in decreased expression of UBE2H mRNA CTD PMID:22538082 NCBI chr 7:129,830,732...129,952,960
Ensembl chr 7:129,830,732...129,952,960
JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I decreases expression ISO Phlorhizin results in decreased expression of UBE2I mRNA CTD PMID:22538082 NCBI chr16:1,309,152...1,327,017
Ensembl chr16:1,308,880...1,327,018
JBrowse link
G UBE2L3 ubiquitin conjugating enzyme E2 L3 decreases expression ISO Phlorhizin results in decreased expression of UBE2L3 mRNA CTD PMID:22538082 NCBI chr22:21,549,447...21,624,034
Ensembl chr22:21,549,447...21,624,034
JBrowse link
G UBE2M ubiquitin conjugating enzyme E2 M increases expression ISO Phlorhizin results in increased expression of UBE2M mRNA CTD PMID:22538082 NCBI chr19:58,555,712...58,558,611
Ensembl chr19:58,555,712...58,558,954
JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N decreases expression ISO Phlorhizin results in decreased expression of UBE2N mRNA CTD PMID:22538082 NCBI chr12:93,405,684...93,442,336
Ensembl chr12:93,405,673...93,441,947
JBrowse link
G UBE2Q1 ubiquitin conjugating enzyme E2 Q1 increases expression ISO Phlorhizin results in increased expression of UBE2Q1 mRNA CTD PMID:22538082 NCBI chr 1:154,548,577...154,558,662
Ensembl chr 1:154,548,577...154,559,028
JBrowse link
G UBE2R2 ubiquitin conjugating enzyme E2 R2 decreases expression ISO Phlorhizin results in decreased expression of UBE2R2 mRNA CTD PMID:22538082 NCBI chr 9:33,817,160...33,920,399
Ensembl chr 9:33,817,160...33,920,399
JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 decreases expression ISO Phlorhizin results in decreased expression of UBE2V2 mRNA CTD PMID:22538082 NCBI chr 8:47,997,527...48,064,708
Ensembl chr 8:48,008,415...48,064,708
JBrowse link
G UBE4A ubiquitination factor E4A increases expression ISO Phlorhizin results in increased expression of UBE4A mRNA CTD PMID:22538082 NCBI chr11:118,359,600...118,399,211
Ensembl chr11:118,359,585...118,399,211
Ensembl chr11:118,359,585...118,399,211
JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Phlorhizin results in increased expression of UBR2 mRNA CTD PMID:22538082 NCBI chr 6:42,563,954...42,693,505
Ensembl chr 6:42,564,062...42,693,504
Ensembl chr 6:42,564,062...42,693,504
JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Phlorhizin results in decreased expression of UCHL3 mRNA CTD PMID:22538082 NCBI chr13:75,549,490...75,606,020
Ensembl chr13:75,549,480...75,606,020
JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 decreases expression ISO Phlorhizin results in decreased expression of UCHL5 mRNA CTD PMID:22538082 NCBI chr 1:193,012,254...193,060,140
Ensembl chr 1:193,012,250...193,060,080
JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 decreases expression ISO Phlorhizin results in decreased expression of UQCRC2 mRNA CTD PMID:22538082 NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660
JBrowse link
G USP1 ubiquitin specific peptidase 1 increases expression ISO Phlorhizin results in increased expression of USP1 mRNA CTD PMID:22538082 NCBI chr 1:62,436,395...62,451,804
Ensembl chr 1:62,436,297...62,451,804
JBrowse link
G USP14 ubiquitin specific peptidase 14 decreases expression ISO Phlorhizin results in decreased expression of USP14 mRNA CTD PMID:22538082 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629
JBrowse link
G USP19 ubiquitin specific peptidase 19 increases expression ISO Phlorhizin results in increased expression of USP19 mRNA CTD PMID:22538082 NCBI chr 3:49,108,050...49,120,933
Ensembl chr 3:49,108,046...49,120,938
JBrowse link
G USP24 ubiquitin specific peptidase 24 decreases expression ISO Phlorhizin results in decreased expression of USP24 mRNA CTD PMID:22538082 NCBI chr 1:55,066,359...55,215,374
Ensembl chr 1:55,066,359...55,215,364
JBrowse link
G USP33 ubiquitin specific peptidase 33 decreases expression ISO Phlorhizin results in decreased expression of USP33 mRNA CTD PMID:22538082 NCBI chr 1:77,695,987...77,759,852
Ensembl chr 1:77,695,987...77,759,852
JBrowse link
G USP4 ubiquitin specific peptidase 4 increases expression ISO Phlorhizin results in increased expression of USP4 mRNA CTD PMID:22538082 NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712
JBrowse link
G USP45 ubiquitin specific peptidase 45 decreases expression ISO Phlorhizin results in decreased expression of USP45 mRNA CTD PMID:22538082 NCBI chr 6:99,432,325...99,515,770
Ensembl chr 6:99,432,325...99,521,728
Ensembl chr 6:99,432,325...99,521,728
JBrowse link
G USP46 ubiquitin specific peptidase 46 decreases expression ISO Phlorhizin results in decreased expression of USP46 mRNA CTD PMID:22538082 NCBI chr 4:52,590,960...52,659,301
Ensembl chr 4:52,590,960...52,659,301
JBrowse link
G USP7 ubiquitin specific peptidase 7 decreases expression ISO Phlorhizin results in decreased expression of USP7 mRNA CTD PMID:22538082 NCBI chr16:8,892,097...8,963,912
Ensembl chr16:8,892,097...8,975,328
Ensembl chr16:8,892,097...8,975,328
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked decreases expression ISO Phlorhizin results in decreased expression of USP9X mRNA CTD PMID:22538082 NCBI chr  X:41,085,420...41,236,579
Ensembl chr  X:41,085,445...41,236,579
JBrowse link
G XIAP X-linked inhibitor of apoptosis decreases expression ISO Phlorhizin results in decreased expression of XIAP mRNA CTD PMID:22538082 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,724...123,913,976
Ensembl chr  X:123,859,724...123,913,976
JBrowse link
trilobatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein] CTD PMID:30104959 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:30104959 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CAT catalase multiple interactions ISO NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein] CTD PMID:32663520 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G ESRRA estrogen related receptor alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein] CTD PMID:30104959 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743
Ensembl chr11:64,305,497...64,316,743
JBrowse link
G FOXO3 forkhead box O3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein] CTD PMID:30104959 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein] CTD PMID:30104959 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]
trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 protein]
CTD PMID:30104959 PMID:32663520 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein] CTD PMID:30104959 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,504
Ensembl chr15:90,083,045...90,102,504
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:25053100 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:25053100 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] CTD PMID:30104959 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP6 mRNA] CTD PMID:30104959 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207
JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COX1 mRNA] CTD PMID:30104959 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
JBrowse link
G MT-CYB mitochondrially encoded cytochrome b multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CYTB mRNA] CTD PMID:30104959 NCBI chr MT:14,747...15,887
Ensembl chr MT:14,747...15,887
JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND2 mRNA] CTD PMID:30104959 NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511
JBrowse link
G MT-ND5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND5 mRNA] CTD PMID:30104959 NCBI chr MT:12,337...14,148
Ensembl chr MT:12,337...14,148
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions ISO NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin promotes the reaction [Isoflurane results in increased expression of NFE2L2 protein]
trilobatin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]
CTD PMID:30104959 PMID:32663520 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:25053100 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 protein]
trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]
CTD PMID:30104959 PMID:32663520 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein] CTD PMID:30104959 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:25053100 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G SIRT3 sirtuin 3 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein] CTD PMID:30104959 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein]; trilobatin inhibits the reaction [Hydrogen Peroxide results in increased acetylation of SOD2 protein] CTD PMID:30104959 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; trilobatin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:25053100 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G UCP2 uncoupling protein 2 multiple interactions ISO trilobatin inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein] CTD PMID:30104959 NCBI chr11:73,974,671...73,983,202
Ensembl chr11:73,974,672...73,983,246
Ensembl chr11:73,974,672...73,983,246
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24387
    role 24297
      biological role 24264
        biochemical role 23652
          metabolite 23571
            eukaryotic metabolite 23311
              plant metabolite 19893
                dihydrochalcone 278
                  2',4',6'-trihydroxy-3'-formyldihydrochalcone 0
                  2',6'-dihydroxy-4'-methoxydihydrochalcone 0
                  davidigenin 0
                  phloretin + 278
Path 2
Term Annotations click to browse term
  CHEBI ontology 24387
    subatomic particle 24344
      composite particle 24344
        hadron 24344
          baryon 24344
            nucleon 24344
              atomic nucleus 24344
                atom 24344
                  main group element atom 24191
                    p-block element atom 24191
                      carbon group element atom 23974
                        carbon atom 23934
                          organic molecular entity 23934
                            organic group 22220
                              organic divalent group 22194
                                organodiyl group 22194
                                  carbonyl group 22177
                                    carbonyl compound 22177
                                      ketone 18431
                                        aromatic ketone 13391
                                          dihydrochalcones 790
                                            dihydrochalcone 278
                                              2',4',6'-trihydroxy-3'-formyldihydrochalcone 0
                                              2',6'-dihydroxy-4'-methoxydihydrochalcone 0
                                              davidigenin 0
                                              phloretin + 278
paths to the root