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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:omacetaxine mepesuccinate
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Accession:CHEBI:71019 term browser browse the term
Definition:A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia.
Synonyms:related_synonym: (2'R,3S,4S,5R)-(-)-homoharringtonine;   CGX-635;   Formula=C29H39NO9;   Homoharringtonine;   InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1;   InChIKey=HYFHYPWGAURHIV-JFIAXGOJSA-N;   SMILES=[H][C@@]12[C@H](OC(=O)[C@@](O)(CCCC(C)(C)O)CC(=O)OC)C(OC)=C[C@@]11CCCN1CCc1cc3OCOc3cc21;   Synribo;   mepesuccinate d'omacetaxine;   mepesuccinato de omacetaxina;   omacetaxini mepesuccinas
 xref: Beilstein:5687925;   CAS:26833-87-4;   Drug_Central:4677;   KEGG:D08956;   LINCS:LSM-3716
 xref_mesh: MESH:C001652
 xref: PDBeChem:HMT;   PMID:20971952;   PMID:21152934;   PMID:21258877;   PMID:21294709;   PMID:21415308;   PMID:21418889;   PMID:21468038;   PMID:21509439;   PMID:21845438;   PMID:21916787;   PMID:22040954;   PMID:22054289;   PMID:22075327;   PMID:22289991;   PMID:22391162;   PMID:22580751;   PMID:22714632;   PMID:22896000;   PMID:22898909;   PMID:22917222;   PMID:22967374;   PMID:23053254;   PMID:23059828;   PMID:23086639;   PMID:23109844;   PMID:23456623;   Patent:US2010240887;   Patent:WO2007089878;   Reaxys:5687925;   Wikipedia:Omacetaxine_mepesuccinate

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  CHEBI ontology 0
    role 0
      biological role 0
        biochemical role 0
          apoptosis inducer 0
            omacetaxine mepesuccinate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic molecule 0
                              organic cyclic compound 0
                                organic heterocyclic compound 0
                                  organic heteropolycyclic compound 0
                                    organic heterobicyclic compound 0
                                      benzazepine 0
                                        benzazepine alkaloid 0
                                          cephalotaxine 0
                                            omacetaxine mepesuccinate 0
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