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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antileishmanial agent
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Accession:CHEBI:70868 term browser browse the term
Definition:An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
Synonyms:related_synonym: antileishmanial agents;   antileishmanial drug;   antileishmanial drugs


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acivicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator multiple interactions ISO acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein]; acivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of CFTR mRNA] CTD PMID:14766015 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions
decreases activity
ISO [acivicin results in decreased activity of GGT1 protein] which results in decreased susceptibility to Glutathione CTD PMID:15629191, PMID:19419996 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
acteoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
decreases localization
ISO acteoside promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]
acteoside results in decreased localization of AHR protein
CTD PMID:21756928 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases localization ISO acteoside results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
decreases secretion
ISO acteoside results in decreased expression of CCL2 mRNA
acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
acteoside results in decreased secretion of CCL2 protein
CTD PMID:21756928, PMID:21967610 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO acteoside results in decreased expression of CCND1 protein CTD PMID:17634406 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO acteoside results in decreased expression of CCND2 protein CTD PMID:17634406 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO acteoside results in decreased expression of CCND3 protein CTD PMID:17634406 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO acteoside results in decreased expression of CCNE1 protein CTD PMID:17634406 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO acteoside results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:17634406 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity
multiple interactions
ISO acteoside results in decreased activity of CDK4 protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]
CTD PMID:17634406 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]; acteoside results in decreased expression of and results in decreased activity of CDK6 protein CTD PMID:17634406 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO acteoside results in increased expression of CDKN1A mRNA; acteoside results in increased expression of CDKN1A protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]
CTD PMID:17634406 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO acteoside results in increased expression of CDKN1B mRNA; acteoside results in increased expression of CDKN1B protein
acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]
CTD PMID:17634406 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases secretion
decreases expression
multiple interactions
ISO acteoside results in decreased secretion of CXCL10 protein
acteoside results in decreased expression of CXCL10 mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [PD168393 results in increased secretion of CXCL10 protein]; acteoside promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein]
CTD PMID:21756928, PMID:21967610 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO acteoside results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:14672760 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein] CTD PMID:17634406 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation
multiple interactions
ISO acteoside results in decreased phosphorylation of EGFR protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein]
CTD PMID:21756928, PMID:21967610 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO acteoside results in decreased expression of ICAM1 mRNA CTD PMID:21371465 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
ISO acteoside results in decreased expression of IFNG mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
CTD PMID:21371465, PMID:21756928 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
acteoside results in decreased expression of IL6 mRNA
CTD PMID:21756928 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO acteoside inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] CTD PMID:16393473 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
decreases phosphorylation
ISO acteoside results in increased phosphorylation of MAPK1 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]
acteoside results in decreased phosphorylation of MAPK1 protein
CTD PMID:21756928, PMID:23527233 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO acteoside results in decreased phosphorylation of MAPK3 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]
acteoside results in increased phosphorylation of MAPK3 protein
CTD PMID:21756928, PMID:23527233 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nox1 NADPH oxidase 1 decreases activity ISO acteoside results in decreased activity of NOX1 protein CTD PMID:16393473 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO acteoside binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [acteoside co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA CTD PMID:21756928 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation
multiple interactions
ISO acteoside results in decreased phosphorylation of RB1 protein
[acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein]
CTD PMID:17634406 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
decreases phosphorylation
ISO acteoside results in increased phosphorylation of RELA protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
acteoside results in decreased phosphorylation of RELA protein
CTD PMID:21756928, PMID:23527233 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation ISO acteoside results in increased phosphorylation of SMAD2 protein CTD PMID:17634406 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 increases phosphorylation ISO acteoside results in increased phosphorylation of SMAD3 protein CTD PMID:17634406 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO acteoside results in decreased expression of SOD2 mRNA CTD PMID:21371465 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO [acteoside co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21756928, PMID:21967610 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO acteoside results in increased expression of TGFB1 mRNA CTD PMID:17634406 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO acteoside results in decreased expression of VCAM1 mRNA CTD PMID:21371465 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
ascaridole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor affects response to substance ISO ERCC6 protein affects the susceptibility to ascaridole CTD PMID:22280988 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor affects response to substance ISO XPC protein affects the susceptibility to ascaridole CTD PMID:22280988 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
flavokawain B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO flavokawain B results in decreased phosphorylation of AKT1 protein
TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of AKT1 protein]
CTD PMID:30025493 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of ATF4 protein]; ATF4 protein affects the reaction [flavokawain B results in increased expression of DDIT3 protein]; ATF4 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATF4 protein affects the reaction [flavokawain B results in increased expression of TRIB3 protein] CTD PMID:30025493 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg5 autophagy related 5 multiple interactions
affects response to substance
ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of CDKN1A protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of GLB1 protein; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MAP1LC3B protein modified form; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MKI67 protein; ATG5 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form] CTD PMID:30025493 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 affects response to substance
multiple interactions
ISO ATG7 protein affects the susceptibility to flavokawain B
[ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein; [ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; ATG7 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]
CTD PMID:30025493 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein; [ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of CASP3 protein CTD PMID:30025493 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of CDKN1A protein; [Chloroquine co-treated with flavokawain B] results in decreased expression of CDKN1A protein CTD PMID:30025493 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of DDIT3 protein]; ATF4 protein affects the reaction [flavokawain B results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form] CTD PMID:30025493 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO flavokawain B results in increased phosphorylation of EIF2AK3 protein CTD PMID:30025493 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO flavokawain B results in increased phosphorylation of EIF2S1 protein CTD PMID:30025493 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
increases expression
ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of GLB1 protein; [Chloroquine co-treated with flavokawain B] results in decreased expression of GLB1 protein
flavokawain B results in increased expression of GLB1 protein
CTD PMID:30025493 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO flavokawain B results in increased expression of HSPA5 protein CTD PMID:30025493 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO 3-methyladenine inhibits the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; 4-phenylbutyric acid inhibits the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MAP1LC3B protein modified form; [Chloroquine co-treated with flavokawain B] results in increased expression of MAP1LC3B protein modified form; ATF4 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATG4 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATG5 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; ATG7 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; Chloroquine promotes the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form]; DDIT3 protein affects the reaction [flavokawain B results in increased expression of MAP1LC3B protein modified form] CTD PMID:30025493 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of MKI67 protein; [Chloroquine co-treated with flavokawain B] results in decreased expression of MKI67 protein CTD PMID:30025493 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation
ISO TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of MTOR protein] CTD PMID:30025493 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; [ATG7 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein; [flavokawain B co-treated with 3-methyladenine] results in increased cleavage of PARP1 protein CTD PMID:30025493 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation
multiple interactions
ISO flavokawain B results in decreased phosphorylation of RPS6KB1 protein
TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of RPS6KB1 protein]
CTD PMID:30025493 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO flavokawain B results in increased expression of SQSTM1 protein CTD PMID:30025493 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions
increases expression
ISO ATF4 protein affects the reaction [flavokawain B results in increased expression of TRIB3 protein]; TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of AKT1 protein]; TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of MTOR protein]; TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30025493 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
geranylgeraniol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 increases chemical synthesis ISO AKR1B10 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases chemical synthesis ISO AKR1C3 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Casp3 caspase 3 increases activity ISO geranylgeraniol results in increased activity of CASP3 protein CTD PMID:9175767 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO geranylgeraniol inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] CTD PMID:15314095 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein] CTD PMID:19530242 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Egf epidermal growth factor multiple interactions ISO geranylgeraniol analog inhibits the reaction [EGF protein results in increased phosphorylation of RHOA protein] CTD PMID:24587105 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO geranylgeraniol inhibits the reaction [Fluvastatin results in decreased expression of F3 protein]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased expression of F3] CTD PMID:9081680, PMID:12753293 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases activity
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to geranylgeraniol; MVK gene mutant form promotes the reaction [geranylgeraniol results in decreased activity of HMGCR protein] CTD PMID:12477733, PMID:19819230 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO geranylgeraniol inhibits the reaction [zoledronic acid results in increased expression of IBSP mRNA] CTD PMID:15324309 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO geranylgeraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]
geranylgeraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]
CTD PMID:20304105 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO
EXP
geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO
EXP
geranylgeraniol inhibits the reaction [Atorvastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]]; geranylgeraniol inhibits the reaction [Pravastatin results in increased expression of [ITGA2 protein binds to ITGB1 protein]] CTD PMID:12500026 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Mvk mevalonate kinase multiple interactions ISO [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to geranylgeraniol; geranylgeraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geranylgeraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides]; MVK gene mutant form promotes the reaction [geranylgeraniol results in decreased activity of HMGCR protein] CTD PMID:12477733, PMID:20304105 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Myl9 myosin light chain 9 multiple interactions ISO geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein] CTD PMID:24587105 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT mRNA]; geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT] CTD PMID:12371961, PMID:12753293 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO geranylgeraniol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]] CTD PMID:24449418 NCBI chr 7:51,404,971...51,515,382
Ensembl chr 7:51,404,919...51,515,373
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A multiple interactions EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R14A protein]] CTD PMID:24449418 NCBI chr 1:87,224,683...87,232,842
Ensembl chr 1:87,224,677...87,232,848
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RAC1 protein] CTD PMID:12933658 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form; geranylgeraniol inhibits the reaction [zoledronic acid results in decreased geranoylation of RAP1A protein] CTD PMID:16539721, PMID:19819230 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO
EXP
geranylgeraniol analog inhibits the reaction [EGF protein results in increased phosphorylation of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of and affects the localization of RHOA protein]
geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein]]
CTD PMID:9398081, PMID:12477733, PMID:12933658, PMID:15324309, PMID:24449418, PMID:24587105 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rhoc ras homolog family member C multiple interactions ISO geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] CTD PMID:24587105 NCBI chr 2:207,271,692...207,278,010
Ensembl chr 2:207,271,853...207,279,314
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO geranylgeraniol inhibits the reaction [cerivastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]] CTD PMID:11779144 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sele selectin E multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]] CTD PMID:16740276 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]] CTD PMID:16740276 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
quercitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO quercitrin results in decreased expression of ABCC4 mRNA CTD PMID:25193878 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 increases expression ISO quercitrin results in increased expression of ABCF2 mRNA CTD PMID:25193878 NCBI chr 4:7,122,850...7,135,607
Ensembl chr 4:7,122,890...7,135,669
JBrowse link
G Acbd6 acyl-CoA binding domain containing 6 decreases expression ISO quercitrin results in decreased expression of ACBD6 mRNA CTD PMID:25193878 NCBI chr13:73,196,504...73,334,077
Ensembl chr13:73,196,571...73,334,077
JBrowse link
G Acbd7 acyl-CoA binding domain containing 7 increases expression ISO quercitrin results in increased expression of ACBD7 mRNA CTD PMID:25193878 NCBI chr17:78,904,549...78,913,372
Ensembl chr17:78,904,873...78,910,671
JBrowse link
G Actn1 actinin, alpha 1 affects expression ISO quercitrin affects the expression of ACTN1 mRNA CTD PMID:25193878 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 affects expression ISO quercitrin affects the expression of ACTN4 mRNA CTD PMID:25193878 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 decreases expression ISO quercitrin results in decreased expression of ADGRB1 mRNA CTD PMID:25193878 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO quercitrin results in decreased expression of ADGRF1 mRNA CTD PMID:25193878 NCBI chr 9:20,343,730...20,378,686 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO quercitrin results in decreased expression of ADGRG1 mRNA CTD PMID:25193878 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 decreases expression ISO quercitrin results in decreased expression of ADGRG6 mRNA CTD PMID:25193878 NCBI chr 1:8,593,342...8,751,540
Ensembl chr 1:8,593,075...8,751,198
JBrowse link
G Adgrg7 adhesion G protein-coupled receptor G7 increases expression ISO quercitrin results in increased expression of ADGRG7 mRNA CTD PMID:25193878 NCBI chr11:46,103,173...46,172,303
Ensembl chr11:46,793,777...46,856,291
Ensembl chr11:46,793,777...46,856,291
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 increases expression ISO quercitrin results in increased expression of ADGRV1 mRNA CTD PMID:25193878 NCBI chr 2:8,926,843...9,504,455
Ensembl chr 2:8,926,850...9,504,134
JBrowse link
G Adk adenosine kinase decreases expression ISO quercitrin results in decreased expression of ADK mRNA CTD PMID:25193878 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adra2c adrenoceptor alpha 2C increases expression ISO quercitrin results in increased expression of ADRA2C mRNA CTD PMID:25193878 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO quercitrin results in increased expression of AHNAK2 mRNA CTD PMID:25193878 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Alkbh7 alkB homolog 7 increases expression ISO quercitrin results in increased expression of ALKBH7 mRNA CTD PMID:25193878 NCBI chr 9:10,045,375...10,047,507
Ensembl chr 9:10,045,375...10,047,507
JBrowse link
G Anapc15 anaphase promoting complex subunit 15 decreases expression ISO quercitrin results in decreased expression of ANAPC15 mRNA CTD PMID:25193878 NCBI chr 1:166,981,738...166,985,363
Ensembl chr 1:166,983,175...166,985,054
JBrowse link
G Ar androgen receptor increases expression ISO quercitrin results in increased expression of AR mRNA CTD PMID:25193878 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 increases expression ISO quercitrin results in increased expression of ARAP2 mRNA CTD PMID:25193878 NCBI chr14:48,726,033...48,922,809
Ensembl chr14:48,726,045...48,922,983
JBrowse link
G Asb6 ankyrin repeat and SOCS box-containing 6 increases expression ISO quercitrin results in increased expression of ASB6 mRNA CTD PMID:25193878 NCBI chr 3:9,659,707...9,664,445
Ensembl chr 3:9,659,710...9,664,318
JBrowse link
G Atg7 autophagy related 7 decreases expression ISO quercitrin results in decreased expression of ATG7 mRNA CTD PMID:25193878 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 affects expression ISO quercitrin affects the expression of BAIAP2 mRNA CTD PMID:25193878 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein] CTD PMID:23138875 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bdkrb1 bradykinin receptor B1 decreases expression ISO quercitrin results in decreased expression of BDKRB1 mRNA CTD PMID:25193878 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO quercitrin results in decreased expression of CAMK2B mRNA CTD PMID:25193878 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
quercitrin results in increased activity of CASP3 protein
quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]
CTD PMID:23138875, PMID:25193878 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression ISO quercitrin results in increased expression of CASP8 mRNA CTD PMID:25193878 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 decreases expression ISO quercitrin results in decreased expression of CCR9 mRNA CTD PMID:25193878 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 increases expression ISO quercitrin results in increased expression of CCRL2 mRNA CTD PMID:25193878 NCBI chr 8:119,324,298...119,326,954
Ensembl chr 8:119,324,613...119,326,938
JBrowse link
G Cd302 CD302 molecule decreases expression ISO quercitrin results in decreased expression of CD302 mRNA CTD PMID:25193878 NCBI chr 3:46,327,382...46,361,092
Ensembl chr 3:46,327,383...46,361,092
JBrowse link
G Cd38 CD38 molecule decreases expression ISO quercitrin results in decreased expression of CD38 mRNA CTD PMID:25193878 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd74 CD74 molecule affects expression ISO quercitrin affects the expression of CD74 mRNA CTD PMID:25193878 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO quercitrin results in decreased expression of CDH1 mRNA CTD PMID:25193878 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO quercitrin results in decreased expression of CDKN3 mRNA CTD PMID:25193878 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO quercitrin results in increased expression of CELSR3 mRNA CTD PMID:25193878 NCBI chr 8:117,620,293...117,648,034
Ensembl chr 8:117,620,317...117,648,028
JBrowse link
G Cep95 centrosomal protein 95 increases expression ISO quercitrin results in increased expression of CEP95 mRNA CTD PMID:25193878 NCBI chr10:94,988,362...95,017,774
Ensembl chr10:94,988,362...95,016,344
JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO quercitrin results in increased expression of CERS5 mRNA CTD PMID:25193878 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Cfap298 cilia and flagella associated protein 298 decreases expression ISO quercitrin results in decreased expression of CFAP298 mRNA CTD PMID:25193878 NCBI chr11:31,094,103...31,103,487
Ensembl chr11:31,094,084...31,103,520
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 decreases expression ISO quercitrin results in decreased expression of CHD2 mRNA CTD PMID:25193878 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Cldn10 claudin 10 affects expression ISO quercitrin affects the expression of CLDN10 mRNA CTD PMID:25193878 NCBI chr15:104,026,590...104,115,748
Ensembl chr15:104,026,601...104,115,748
JBrowse link
G Cldn23 claudin 23 affects expression ISO quercitrin affects the expression of CLDN23 mRNA CTD PMID:25193878 NCBI chr16:59,988,603...59,990,327
Ensembl chr16:59,988,603...59,990,326
JBrowse link
G Cldn4 claudin 4 affects expression ISO quercitrin affects the expression of CLDN4 mRNA CTD PMID:25193878 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn8 claudin 8 affects expression ISO quercitrin affects the expression of CLDN8 mRNA CTD PMID:25193878 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO quercitrin results in decreased expression of COL3A1 mRNA CTD PMID:25193878 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO quercitrin results in decreased expression of COQ3 mRNA CTD PMID:25193878 NCBI chr 5:36,024,673...36,056,664
Ensembl chr 5:36,024,649...36,056,669
JBrowse link
G Crisp1 cysteine-rich secretory protein 1 decreases expression ISO quercitrin results in decreased expression of CRISP1 mRNA CTD PMID:25193878 NCBI chr 9:24,356,577...24,383,679
Ensembl chr 9:24,356,579...24,383,679
JBrowse link
G Cryzl1 crystallin zeta like 1 decreases expression ISO quercitrin results in decreased expression of CRYZL1 mRNA CTD PMID:25193878 NCBI chr11:31,847,741...31,893,042
Ensembl chr11:31,847,745...31,892,531
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 affects expression ISO quercitrin affects the expression of CSNK2A1 mRNA CTD PMID:25193878 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression ISO quercitrin affects the expression of CSNK2A2 mRNA CTD PMID:25193878 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Ctdspl2 CTD small phosphatase like 2 decreases expression ISO quercitrin results in decreased expression of CTDSPL2 mRNA CTD PMID:25193878 NCBI chr 3:113,906,803...113,957,289
Ensembl chr 3:113,918,629...113,960,101
JBrowse link
G Ctsb cathepsin B affects expression ISO quercitrin affects the expression of CTSB mRNA CTD PMID:25193878 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO quercitrin results in decreased activity of CYP1A1 protein CTD PMID:16271822 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO quercitrin results in decreased activity of CYP1B1 protein CTD PMID:16271822 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO quercitrin results in increased expression of CYP26B1 mRNA CTD PMID:25193878 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Dcun1d5 defective in cullin neddylation 1 domain containing 5 decreases expression ISO quercitrin results in decreased expression of DCUN1D5 mRNA CTD PMID:25193878 NCBI chr 8:5,437,071...5,458,152
Ensembl chr 8:5,437,071...5,458,152
JBrowse link
G Ddx19b DEAD-box helicase 19B decreases expression ISO quercitrin results in decreased expression of DDX19B mRNA CTD PMID:25193878 NCBI chr19:43,217,199...43,246,196
Ensembl chr19:43,217,161...43,275,287
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 decreases expression ISO quercitrin results in decreased expression of DELE1 mRNA CTD PMID:25193878 NCBI chr18:31,396,897...31,409,914
Ensembl chr18:31,396,922...31,409,907
JBrowse link
G Dgkq diacylglycerol kinase, theta affects expression ISO quercitrin affects the expression of DGKQ mRNA CTD PMID:25193878 NCBI chr14:2,069,409...2,083,370
Ensembl chr14:2,069,409...2,083,370
JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO quercitrin results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
JBrowse link
G Dtwd1 DTW domain containing 1 decreases expression ISO quercitrin results in decreased expression of DTWD1 mRNA CTD PMID:25193878 NCBI chr 3:118,427,790...118,443,003
Ensembl chr 3:118,430,511...118,442,098
JBrowse link
G Egr2 early growth response 2 increases expression ISO quercitrin results in increased expression of EGR2 mRNA CTD PMID:25193878 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit decreases expression ISO quercitrin results in decreased expression of ERCC1 mRNA CTD PMID:25193878 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO quercitrin results in decreased expression of ERCC2 mRNA CTD PMID:25193878 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 increases expression ISO quercitrin results in increased expression of ERI2 mRNA CTD PMID:25193878 NCBI chr 1:189,540,145...189,549,891
Ensembl chr 1:189,540,145...189,549,891
JBrowse link
G Eva1a eva-1 homolog A, regulator of programmed cell death decreases expression ISO quercitrin results in decreased expression of EVA1A mRNA CTD PMID:25193878 NCBI chr 4:112,714,023...112,823,659
Ensembl chr 4:112,773,938...112,823,659
JBrowse link
G F11r F11 receptor affects expression ISO quercitrin affects the expression of F11R mRNA CTD PMID:25193878 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression ISO quercitrin results in increased expression of F2RL1 mRNA CTD PMID:25193878 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression ISO quercitrin results in decreased expression of F2RL2 mRNA CTD PMID:25193878 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO quercitrin results in increased expression of F3 mRNA CTD PMID:25193878 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Faim Fas apoptotic inhibitory molecule increases expression ISO quercitrin results in increased expression of FAIM mRNA CTD PMID:25193878 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Fam102a family with sequence similarity 102, member A increases expression ISO quercitrin results in increased expression of FAM102A mRNA CTD PMID:25193878 NCBI chr 3:11,554,084...11,586,315
Ensembl chr 3:11,554,457...11,586,303
JBrowse link
G Fam216a family with sequence similarity 216, member A decreases expression ISO quercitrin results in decreased expression of FAM216A mRNA CTD PMID:25193878 NCBI chr12:39,679,688...39,688,831
Ensembl chr12:39,679,688...39,688,823
JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C increases expression ISO quercitrin results in increased expression of FAM3C mRNA CTD PMID:25193878 NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO quercitrin results in increased expression of FAM43A mRNA CTD PMID:25193878 NCBI chr11:73,676,601...73,679,003
Ensembl chr11:73,676,601...73,678,984
JBrowse link
G Fam50a family with sequence similarity 50, member A increases expression ISO quercitrin results in increased expression of FAM50A mRNA CTD PMID:25193878 NCBI chr  X:156,392,646...156,399,763
Ensembl chr  X:156,392,630...156,399,760
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO quercitrin results in increased expression of FAS mRNA CTD PMID:25193878 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fdcsp follicular dendritic cell secreted protein decreases expression ISO quercitrin results in decreased expression of FDCSP mRNA CTD PMID:25193878 NCBI chr14:21,818,999...21,823,687
Ensembl chr14:21,819,395...21,823,687
JBrowse link
G Flg filaggrin increases expression ISO quercitrin results in increased expression of FLG mRNA CTD PMID:25193878 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO quercitrin results in increased expression of FZD4 mRNA CTD PMID:25193878 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 increases expression ISO quercitrin results in increased expression of GABBR2 mRNA CTD PMID:25193878 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO quercitrin affects the expression of GADD45 mRNA CTD PMID:25193878 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galk2 galactokinase 2 increases expression ISO quercitrin results in increased expression of GALK2 mRNA CTD PMID:25193878 NCBI chr 3:118,137,097...118,268,838
Ensembl chr 3:118,136,838...118,268,836
JBrowse link
G Galr3 galanin receptor 3 increases expression ISO quercitrin results in increased expression of GALR3 mRNA CTD PMID:25193878 NCBI chr 7:120,271,451...120,276,243
Ensembl chr 7:120,273,117...120,275,581
JBrowse link
G Gimap6 GTPase, IMAP family member 6 increases expression ISO quercitrin results in increased expression of GIMAP6 mRNA CTD PMID:25193878 NCBI chr 4:78,337,528...78,342,937
Ensembl chr 4:78,336,423...78,342,863
JBrowse link
G Glipr1 GLI pathogenesis-related 1 decreases expression ISO quercitrin results in decreased expression of GLIPR1 mRNA CTD PMID:25193878 NCBI chr 7:54,767,828...54,778,823
Ensembl chr 7:54,767,827...54,778,848
JBrowse link
G Golim4 golgi integral membrane protein 4 increases expression ISO quercitrin results in increased expression of GOLIM4 mRNA CTD PMID:25193878 NCBI chr 2:174,321,303...174,413,847
Ensembl chr 2:174,322,673...174,413,236
JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO quercitrin results in increased expression of GPR137B mRNA CTD PMID:25193878 NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
JBrowse link
G Gpr173 G-protein coupled receptor 173 increases expression ISO quercitrin results in increased expression of GPR173 mRNA CTD PMID:25193878 NCBI chr  X:22,417,753...22,418,873
Ensembl chr  X:22,417,753...22,418,873
JBrowse link
G Gpr174 G protein-coupled receptor 174 increases expression ISO quercitrin results in increased expression of GPR174 mRNA CTD PMID:25193878 NCBI chr  X:78,358,347...78,399,944
Ensembl chr  X:78,372,257...78,399,944
JBrowse link
G Gpr19 G protein-coupled receptor 19 increases expression ISO quercitrin results in increased expression of GPR19 mRNA CTD PMID:25193878 NCBI chr 4:168,639,930...168,668,345
Ensembl chr 4:168,639,940...168,656,673
JBrowse link
G Gpr4 G protein-coupled receptor 4 increases expression ISO quercitrin results in increased expression of GPR4 mRNA CTD PMID:25193878 NCBI chr 1:80,125,639...80,136,786
Ensembl chr 1:80,135,391...80,136,880
JBrowse link
G Gpr63 G protein-coupled receptor 63 increases expression ISO quercitrin results in increased expression of GPR63 mRNA CTD PMID:25193878 NCBI chr 5:39,258,438...39,374,187
Ensembl chr 5:39,329,423...39,370,900
JBrowse link
G Gpr83 G protein-coupled receptor 83 increases expression ISO quercitrin results in increased expression of GPR83 mRNA CTD PMID:25193878 NCBI chr 8:13,365,583...13,376,071
Ensembl chr 8:13,365,583...13,376,070
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO quercitrin results in decreased expression of GSTP1 mRNA CTD PMID:25193878 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 increases expression ISO quercitrin results in increased expression of HAVCR2 mRNA CTD PMID:25193878 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO quercitrin results in increased expression of HGF mRNA CTD PMID:25193878 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO quercitrin results in increased expression of HMGA2 mRNA CTD PMID:25193878 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO quercitrin results in decreased expression of HMGB2 mRNA CTD PMID:25193878 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO quercitrin results in decreased expression of HNF4A mRNA CTD PMID:25193878 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects expression ISO quercitrin affects the expression of HSP90AA1 mRNA CTD PMID:25193878 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like affects expression ISO quercitrin affects the expression of HSPA1L mRNA CTD PMID:25193878 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression ISO quercitrin affects the expression of HSPA8 mRNA CTD PMID:25193878 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Ifna1 interferon, alpha 1 affects expression ISO quercitrin affects the expression of IFNA6 mRNA CTD PMID:25193878 NCBI chr 5:106,951,822...106,952,908
Ensembl chr 5:106,952,082...106,952,792
JBrowse link
G Ifng interferon gamma multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects expression ISO quercitrin affects the expression of IGF1R mRNA CTD PMID:25193878 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il15 interleukin 15 decreases expression ISO quercitrin results in decreased expression of IL15 mRNA CTD PMID:25193878 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ino80c INO80 complex subunit C decreases expression ISO quercitrin results in decreased expression of INO80C mRNA CTD PMID:25193878 NCBI chr18:15,995,005...16,009,639
Ensembl chr18:15,995,000...16,009,710
JBrowse link
G Inpp4a inositol polyphosphate-4-phosphatase type I A affects expression ISO quercitrin affects the expression of INPP4A mRNA CTD PMID:25193878 NCBI chr 9:43,889,887...44,006,593
Ensembl chr 9:43,889,473...44,004,325
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D affects expression ISO quercitrin affects the expression of INPP5D mRNA CTD PMID:25193878 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Insr insulin receptor affects expression ISO quercitrin affects the expression of INSR mRNA CTD PMID:25193878 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression ISO quercitrin results in increased expression of IRF2BP2 mRNA CTD PMID:25193878 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO quercitrin affects the expression of ITGB1 mRNA CTD PMID:25193878 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Jaml junction adhesion molecule like increases expression ISO quercitrin results in increased expression of JAML mRNA CTD PMID:25193878 NCBI chr 8:49,378,644...49,408,894
Ensembl chr 8:49,378,644...49,410,088
JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 increases expression ISO quercitrin results in increased expression of JPT2 mRNA CTD PMID:25193878 NCBI chr10:14,304,108...14,324,170
Ensembl chr10:14,304,104...14,324,211
JBrowse link
G Kat5 lysine acetyltransferase 5 affects expression ISO quercitrin affects the expression of TIP60 mRNA CTD PMID:25193878 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO quercitrin results in increased expression of KDM3A mRNA CTD PMID:25193878 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdr kinase insert domain receptor increases expression ISO quercitrin results in increased expression of KDR mRNA CTD PMID:25193878 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO quercitrin results in increased expression of KEAP1 mRNA CTD PMID:25193878 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kir3dl1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 affects expression ISO quercitrin affects the expression of KIR3DL3 mRNA CTD PMID:25193878 NCBI chr 1:73,306,564...73,345,009
Ensembl chr 1:73,307,569...73,344,955
JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO quercitrin results in increased expression of KLHL28 mRNA CTD PMID:25193878 NCBI chr 6:86,680,826...86,713,370
Ensembl chr 6:86,684,413...86,713,370
JBrowse link
G Krt81 keratin 81 decreases expression ISO quercitrin results in decreased expression of KRT81 mRNA CTD PMID:25193878 NCBI chr 7:143,107,901...143,113,006
Ensembl chr 7:143,107,901...143,112,960
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 affects expression ISO quercitrin affects the expression of LEF1 mRNA CTD PMID:25193878 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects expression ISO quercitrin affects the expression of HLA-A mRNA CTD PMID:25193878 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC100911237 zinc finger protein 420-like increases expression ISO quercitrin results in increased expression of ZNF502 mRNA CTD PMID:25193878 NCBI chr 1:31,494,043...31,519,034 JBrowse link
G LOC102552569 P2Y purinoceptor 11-like increases expression ISO quercitrin results in increased expression of P2RY11 mRNA CTD PMID:25193878 NCBI chr 8:21,910,636...21,911,499 JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 increases expression ISO quercitrin results in increased expression of LPAR3 mRNA CTD PMID:25193878 NCBI chr 2:252,090,634...252,159,221
Ensembl chr 2:252,090,669...252,159,903
JBrowse link
G Lpar5 lysophosphatidic acid receptor 5 increases expression ISO quercitrin results in increased expression of LPAR5 mRNA CTD PMID:25193878 NCBI chr 4:157,581,000...157,596,454
Ensembl chr 4:157,594,436...157,595,972
JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 decreases expression ISO quercitrin results in decreased expression of LPAR6 mRNA CTD PMID:25193878 NCBI chr15:55,126,953...55,128,762
Ensembl chr15:55,126,953...55,128,761
JBrowse link
G Mat2a methionine adenosyltransferase 2A increases expression ISO quercitrin results in increased expression of MAT2A mRNA CTD PMID:25193878 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mc1r melanocortin 1 receptor increases expression ISO quercitrin results in increased expression of MC1R mRNA CTD PMID:25193878 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mcts1 MCTS1, re-initiation and release factor decreases expression ISO quercitrin results in decreased expression of MCTS1 mRNA CTD PMID:25193878 NCBI chr  X:124,894,269...124,906,129
Ensembl chr  X:124,894,466...124,906,162
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression ISO quercitrin results in decreased expression of MRPL12 mRNA CTD PMID:25193878 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 decreases expression ISO quercitrin results in decreased expression of MRPL22 mRNA CTD PMID:25193878 NCBI chr10:43,601,786...43,612,119
Ensembl chr10:43,601,689...43,612,121
JBrowse link
G Msn moesin affects expression ISO quercitrin affects the expression of MSN mRNA CTD PMID:25193878 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Myl2 myosin light chain 2 affects expression ISO quercitrin affects the expression of MYL2 mRNA CTD PMID:25193878 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myl9 myosin light chain 9 affects expression ISO quercitrin affects the expression of MYL9 mRNA CTD PMID:25193878 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Myom2 myomesin 2 increases expression ISO quercitrin results in increased expression of MYOM2 mRNA CTD PMID:25193878 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit decreases expression ISO quercitrin results in decreased expression of LSMD1 mRNA CTD PMID:25193878 NCBI chr10:55,997,614...55,998,691
Ensembl chr10:55,997,614...55,998,691
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein] CTD PMID:23138875 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein increases expression ISO quercitrin results in increased expression of NFRKB mRNA CTD PMID:25193878 NCBI chr 8:32,530,412...32,561,955
Ensembl chr 8:32,530,412...32,561,955
JBrowse link
G Nmur1 neuromedin U receptor 1 decreases expression ISO quercitrin results in decreased expression of NMUR1 mRNA CTD PMID:25193878 NCBI chr 9:93,402,871...93,407,264
Ensembl chr 9:93,403,314...93,404,883
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npbwr1 neuropeptides B and W receptor 1 increases expression ISO quercitrin results in increased expression of NPBWR1 mRNA CTD PMID:25193878 NCBI chr 5:13,379,772...13,380,761
Ensembl chr 5:13,379,772...13,380,761
JBrowse link
G Npffr2 neuropeptide FF receptor 2 decreases expression ISO quercitrin results in decreased expression of NPFFR2 mRNA CTD PMID:25193878 NCBI chr14:20,148,485...20,193,577
Ensembl chr14:20,148,913...20,193,083
JBrowse link
G Npy5r neuropeptide Y receptor Y5 increases expression ISO quercitrin results in increased expression of NPY5R mRNA CTD PMID:25193878 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Nuak2 NUAK family kinase 2 decreases expression ISO quercitrin results in decreased expression of NUAK2 mRNA CTD PMID:25193878 NCBI chr13:49,092,306...49,109,055
Ensembl chr13:49,092,306...49,109,050
JBrowse link
G Ocln occludin affects expression ISO quercitrin affects the expression of OCLN mRNA CTD PMID:25193878 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO quercitrin results in increased expression of ODC1 mRNA CTD PMID:25193878 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Oga O-GlcNAcase increases expression ISO quercitrin results in increased expression of OGA mRNA CTD PMID:25193878 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G Ogfod2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 increases expression ISO quercitrin results in increased expression of OGFOD2 mRNA CTD PMID:25193878 NCBI chr12:37,907,130...37,910,446
Ensembl chr12:37,907,130...37,910,439
JBrowse link
G Oma1 OMA1 zinc metallopeptidase increases expression ISO quercitrin results in increased expression of OMA1 mRNA CTD PMID:25193878 NCBI chr 5:122,847,624...122,900,475
Ensembl chr 5:122,847,645...122,900,475
JBrowse link
G P2rx2 purinergic receptor P2X 2 increases expression ISO quercitrin results in increased expression of P2RX2 mRNA CTD PMID:25193878 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P2rx3 purinergic receptor P2X 3 increases expression ISO quercitrin results in increased expression of P2RX3 mRNA CTD PMID:25193878 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 decreases expression ISO quercitrin results in decreased expression of P2RY6 mRNA CTD PMID:25193878 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein] CTD PMID:23138875 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Patz1 POZ (BTB) and AT hook containing zinc finger 1 decreases expression ISO quercitrin results in decreased expression of PATZ1 mRNA CTD PMID:25193878 NCBI chr14:83,509,763...83,528,898
Ensembl chr14:83,510,278...83,528,898
JBrowse link
G Pex16 peroxisomal biogenesis factor 16 decreases expression ISO quercitrin results in decreased expression of PEX16 mRNA CTD PMID:25193878 NCBI chr 3:81,283,137...81,292,575
Ensembl chr 3:81,283,137...81,292,573
JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO quercitrin results in increased expression of PIDD1 mRNA CTD PMID:25193878 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha affects expression ISO quercitrin affects the expression of PIK3C2A mRNA CTD PMID:25193878 NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 affects expression ISO quercitrin affects the expression of PIK3R1 mRNA CTD PMID:25193878 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plcb2 phospholipase C, beta 2 affects expression ISO quercitrin affects the expression of PLCB2 mRNA CTD PMID:25193878 NCBI chr 3:110,497,760...110,517,563
Ensembl chr 3:110,498,114...110,517,163
JBrowse link
G Plce1 phospholipase C, epsilon 1 affects expression ISO quercitrin affects the expression of PLCE1 mRNA CTD PMID:25193878 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Plgrkt plasminogen receptor with a C-terminal lysine decreases expression ISO quercitrin results in decreased expression of PLGRKT mRNA CTD PMID:25193878 NCBI chr 1:247,502,274...247,514,540
Ensembl chr 1:247,502,280...247,514,540
JBrowse link
G Poc1a POC1 centriolar protein A decreases expression ISO quercitrin results in decreased expression of POC1A mRNA CTD PMID:25193878 NCBI chr 8:114,982,764...115,050,844
Ensembl chr 8:114,986,326...115,050,728
JBrowse link
G Polh DNA polymerase eta increases expression ISO quercitrin results in increased expression of POLH mRNA CTD PMID:25193878 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polrmt RNA polymerase mitochondrial decreases expression ISO quercitrin results in decreased expression of POLRMT mRNA CTD PMID:25193878 NCBI chr 7:12,840,907...12,851,153
Ensembl chr 7:12,840,938...12,851,153
JBrowse link
G Pomt2 protein-O-mannosyltransferase 2 increases expression ISO quercitrin results in increased expression of POMT2 mRNA CTD PMID:25193878 NCBI chr 6:111,137,329...111,176,991
Ensembl chr 6:111,135,349...111,176,918
JBrowse link
G Pou5f2 POU domain class 5, transcription factor 2 decreases expression ISO quercitrin results in decreased expression of POU5F2 mRNA CTD PMID:25193878 NCBI chr 2:5,437,067...5,438,301
Ensembl chr 2:5,437,067...5,438,301
JBrowse link
G Prkcb protein kinase C, beta affects expression ISO quercitrin affects the expression of PRKCB mRNA CTD PMID:25193878 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prr3 proline rich 3 decreases expression ISO quercitrin results in decreased expression of PRR3 mRNA CTD PMID:25193878 NCBI chr20:3,300,247...3,307,262
Ensembl chr20:3,299,730...3,307,673
JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 increases expression ISO quercitrin results in increased expression of PSD4 mRNA CTD PMID:25193878 NCBI chr 3:1,478,432...1,515,094
Ensembl chr 3:1,478,525...1,514,934
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 decreases expression ISO quercitrin results in decreased expression of PSMA6 mRNA CTD PMID:25193878 NCBI chr 6:76,174,460...76,205,429
Ensembl chr 6:76,174,452...76,205,426
JBrowse link
G Psma8 proteasome 20S subunit alpha 8 decreases expression ISO quercitrin results in decreased expression of PSMA8 mRNA CTD PMID:25193878 NCBI chr18:6,114,757...6,182,393
Ensembl chr18:6,114,701...6,182,535
JBrowse link
G Psmb6 proteasome 20S subunit beta 6 decreases expression ISO quercitrin results in decreased expression of PSMB6 mRNA CTD PMID:25193878 NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression ISO quercitrin results in decreased expression of PSMB9 mRNA CTD PMID:25193878 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 increases expression ISO quercitrin results in increased expression of PTGDR2 mRNA CTD PMID:25193878 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta affects expression ISO quercitrin affects the expression of PTK2B mRNA CTD PMID:25193878 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U decreases expression ISO quercitrin results in decreased expression of PTPRU mRNA CTD PMID:25193878 NCBI chr 5:149,922,374...149,996,352
Ensembl chr 5:149,922,352...149,996,334
JBrowse link
G Rac3 Rac family small GTPase 3 affects expression ISO quercitrin affects the expression of RAC3 mRNA CTD PMID:25193878 NCBI chr10:109,903,920...109,906,596
Ensembl chr10:109,904,259...109,906,232
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family affects expression ISO quercitrin affects the expression of RAP1A mRNA CTD PMID:25193878 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rbak RB-associated KRAB zinc finger increases expression ISO quercitrin results in increased expression of RBAK mRNA CTD PMID:25193878 NCBI chr12:13,428,648...13,442,279
Ensembl chr12:13,428,685...13,442,286
JBrowse link
G Rbks ribokinase decreases expression ISO quercitrin results in decreased expression of RBKS mRNA CTD PMID:25193878 NCBI chr 6:26,051,568...26,128,762
Ensembl chr 6:26,051,396...26,128,906
JBrowse link
G Rbm15b RNA binding motif protein 15B increases expression ISO quercitrin results in increased expression of RBM15B mRNA CTD PMID:25193878 NCBI chr 8:115,618,242...115,623,068
Ensembl chr 8:115,618,555...115,621,394
JBrowse link
G Rbm38 RNA binding motif protein 38 increases expression ISO quercitrin results in increased expression of RBM38 mRNA CTD PMID:25193878 NCBI chr 3:171,037,891...171,050,500
Ensembl chr 3:171,037,957...171,050,475
JBrowse link
G Rbm39 RNA binding motif protein 39 increases expression ISO quercitrin results in increased expression of RBM39 mRNA CTD PMID:25193878 NCBI chr 3:151,691,498...151,724,723
Ensembl chr 3:151,691,514...151,724,654
JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 decreases expression ISO quercitrin results in decreased expression of RCHY1 mRNA CTD PMID:25193878 NCBI chr14:17,615,968...17,631,715
Ensembl chr14:17,615,968...17,631,714
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein] CTD PMID:23138875 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1310553 similar to expressed sequence AI597479 decreases expression ISO quercitrin results in decreased expression of C2ORF49 mRNA CTD PMID:25193878 NCBI chr 9:49,903,085...49,913,754
Ensembl chr 9:49,903,085...49,913,744
JBrowse link
G Riok1 RIO kinase 1 increases expression ISO quercitrin results in increased expression of RIOK1 mRNA CTD PMID:25193878 NCBI chr17:27,429,421...27,452,353
Ensembl chr17:27,429,416...27,452,314
JBrowse link
G Rnf14 ring finger protein 14 decreases expression ISO quercitrin results in decreased expression of RNF14 mRNA CTD PMID:25193878 NCBI chr18:31,443,424...31,468,641
Ensembl chr18:31,444,472...31,468,640
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 affects expression ISO quercitrin affects the expression of ROCK1 mRNA CTD PMID:25193878 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G RT1-Ba RT1 class II, locus Ba affects expression ISO quercitrin affects the expression of HLA-DQA1 mRNA CTD PMID:25193878 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO quercitrin affects the expression of HLA-E mRNA CTD PMID:25193878 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sap18 Sin3A associated protein 18 increases expression ISO quercitrin results in increased expression of SAP18 mRNA CTD PMID:25193878 NCBI chr15:38,069,320...38,073,625
Ensembl chr15:38,069,320...38,073,622
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 decreases expression ISO quercitrin results in decreased expression of SAT1 mRNA CTD PMID:25193878 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO quercitrin results in increased expression of SERTAD1 mRNA CTD PMID:25193878 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 decreases expression ISO quercitrin results in decreased expression of SF3B1 mRNA CTD PMID:25193878 NCBI chr 9:61,594,620...61,634,510
Ensembl chr 9:61,594,620...61,634,510
JBrowse link
G Slc16a13 solute carrier family 16, member 13 decreases expression ISO quercitrin results in decreased expression of SLC16A13 mRNA CTD PMID:25193878 NCBI chr10:56,827,591...56,831,324
Ensembl chr10:56,827,594...56,831,243
JBrowse link
G Slc16a4 solute carrier family 16, member 4 decreases expression ISO quercitrin results in decreased expression of SLC16A4 mRNA CTD PMID:25193878 NCBI chr 2:210,045,122...210,161,017
Ensembl chr 2:210,045,161...210,068,502
JBrowse link
G Slc22a18 solute carrier family 22, member 18 decreases expression ISO quercitrin results in decreased expression of SLC22A18 mRNA CTD PMID:25193878 NCBI chr 1:216,676,330...216,700,632
Ensembl chr 1:216,677,373...216,700,641
JBrowse link
G Slc25a40 solute carrier family 25, member 40 decreases expression ISO quercitrin results in decreased expression of SLC25A40 mRNA CTD PMID:25193878 NCBI chr 4:22,619,700...22,661,685
Ensembl chr 4:22,576,576...22,661,722
JBrowse link
G Slc39a8 solute carrier family 39 member 8 decreases expression ISO quercitrin results in decreased expression of SLC39A8 mRNA CTD PMID:25193878 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582
JBrowse link
G Slc7a9 solute carrier family 7 member 9 increases expression ISO quercitrin results in increased expression of SLC7A9 mRNA CTD PMID:25193878 NCBI chr 1:91,709,034...91,738,492
Ensembl chr 1:91,716,383...91,738,494
JBrowse link
G Slfnl1 schlafen-like 1 increases expression ISO quercitrin results in increased expression of SLFNL1 mRNA CTD PMID:25193878 NCBI chr 5:139,467,933...139,473,599
Ensembl chr 5:139,468,546...139,473,017
JBrowse link
G Smad3 SMAD family member 3 increases expression ISO quercitrin results in increased expression of SMAD3 mRNA CTD PMID:25193878 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 increases expression ISO quercitrin results in increased expression of SMPD1 mRNA CTD PMID:25193878 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Snai2 snail family transcriptional repressor 2 affects expression ISO quercitrin affects the expression of SNAI2 mRNA CTD PMID:25193878 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 affects expression ISO quercitrin affects the expression of SORBS1 mRNA CTD PMID:25193878 NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO quercitrin results in decreased expression of SORL1 mRNA CTD PMID:25193878 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Sp4 Sp4 transcription factor increases expression ISO quercitrin results in increased expression of SP4 mRNA CTD PMID:25193878 NCBI chr 6:146,135,877...146,201,344
Ensembl chr 6:146,135,877...146,195,819
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO quercitrin results in increased expression of SPATA18 mRNA CTD PMID:25193878 NCBI chr14:37,081,529...37,108,245
Ensembl chr14:37,081,427...37,108,341
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects expression ISO quercitrin affects the expression of SRC mRNA CTD PMID:25193878 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 increases expression ISO quercitrin results in increased expression of SRD5A3 mRNA CTD PMID:25193878 NCBI chr14:34,554,769...34,570,423
Ensembl chr14:34,556,220...34,570,356
JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 increases expression ISO quercitrin results in increased expression of SRRM2 mRNA CTD PMID:25193878 NCBI chr10:13,128,820...13,162,956
Ensembl chr10:13,145,099...13,162,343
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase increases expression ISO quercitrin results in increased expression of SUGCT mRNA CTD PMID:25193878 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Sugp1 SURP and G patch domain containing 1 increases expression ISO quercitrin results in increased expression of SUGP1 mRNA CTD PMID:25193878 NCBI chr16:21,100,923...21,131,795
Ensembl chr16:21,100,924...21,131,795
JBrowse link
G Tcea1 transcription elongation factor A1 decreases expression ISO quercitrin results in decreased expression of TCEA1 mRNA CTD PMID:25193878 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429
JBrowse link
G Tcea2 transcription elongation factor A2 decreases expression ISO quercitrin results in decreased expression of TCEA2 mRNA CTD PMID:25193878 NCBI chr 3:177,187,686...177,195,898
Ensembl chr 3:177,188,044...177,195,894
JBrowse link
G Tcf7 transcription factor 7 affects expression ISO quercitrin affects the expression of TCF7 mRNA CTD PMID:25193878 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
G Tfb1m transcription factor B1, mitochondrial decreases expression ISO quercitrin results in decreased expression of TFB1M mRNA CTD PMID:25193878 NCBI chr 1:44,433,116...44,474,674
Ensembl chr 1:44,433,116...44,474,674
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 decreases expression ISO quercitrin results in decreased expression of TGIF2 mRNA CTD PMID:25193878 NCBI chr 3:152,906,961...152,924,380
Ensembl chr 3:152,909,189...152,924,377
JBrowse link
G Tgm2 transglutaminase 2 decreases expression ISO quercitrin results in decreased expression of TGM2 mRNA CTD PMID:25193878 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thsd1 thrombospondin type 1 domain containing 1 increases expression ISO quercitrin results in increased expression of THSD1 mRNA CTD PMID:25193878 NCBI chr16:74,680,621...74,712,368
Ensembl chr16:74,680,621...74,710,704
JBrowse link
G Tmem160 transmembrane protein 160 decreases expression ISO quercitrin results in decreased expression of TMEM160 mRNA CTD PMID:25193878 NCBI chr 1:78,417,719...78,420,427
Ensembl chr 1:78,417,719...78,420,427
JBrowse link
G Tmem208 transmembrane protein 208 decreases expression ISO quercitrin results in decreased expression of TMEM208 mRNA CTD PMID:25193878 NCBI chr19:37,282,018...37,284,718
Ensembl chr19:37,282,018...37,284,718
JBrowse link
G Tmem242 transmembrane protein 242 increases expression ISO quercitrin results in increased expression of TMEM242 mRNA CTD PMID:25193878 NCBI chr 1:46,302,546...46,329,885
Ensembl chr 1:46,302,970...46,329,682
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 decreases expression ISO quercitrin results in decreased expression of TMX1 mRNA CTD PMID:25193878 NCBI chr 6:92,864,123...92,875,141
Ensembl chr 6:92,864,123...92,874,204
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:23138875 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO quercitrin results in decreased expression of TNFRSF1A mRNA CTD PMID:25193878 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B decreases expression ISO quercitrin results in decreased expression of TNFRSF1B mRNA CTD PMID:25193878 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tp63 tumor protein p63 decreases expression ISO quercitrin results in decreased expression of TP63 mRNA CTD PMID:25193878 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tspan14 tetraspanin 14 decreases expression ISO quercitrin results in decreased expression of TSPAN14 mRNA CTD PMID:25193878 NCBI chr16:17,538,855...17,595,960
Ensembl chr16:17,538,855...17,595,960
JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 increases expression ISO quercitrin results in increased expression of U2AF2 mRNA CTD PMID:25193878 NCBI chr 1:72,312,260...72,329,828
Ensembl chr 1:72,312,727...72,329,856
JBrowse link
G Uts2r urotensin 2 receptor increases expression ISO quercitrin results in increased expression of UTS2R mRNA CTD PMID:25193878 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Vwa8 von Willebrand factor A domain containing 8 decreases expression ISO quercitrin results in decreased expression of VWA8 mRNA CTD PMID:25193878 NCBI chr15:61,069,439...61,153,292
NCBI chr15:61,158,510...61,467,462
Ensembl chr15:61,069,581...61,152,506
JBrowse link
G Was WASP actin nucleation promoting factor affects expression ISO quercitrin affects the expression of WAS mRNA CTD PMID:25193878 NCBI chr  X:15,155,246...15,164,099
Ensembl chr  X:15,155,230...15,164,105
JBrowse link
G Wdr33 WD repeat domain 33 decreases expression ISO quercitrin results in decreased expression of WDR33 mRNA CTD PMID:25193878 NCBI chr18:24,584,832...24,689,681
Ensembl chr18:24,584,900...24,689,636
JBrowse link
G Wwox WW domain-containing oxidoreductase decreases expression ISO quercitrin results in decreased expression of WWOX mRNA CTD PMID:25193878 NCBI chr19:46,761,353...47,695,247 JBrowse link
G Zan zonadhesin increases expression ISO quercitrin results in increased expression of ZAN mRNA CTD PMID:25193878 NCBI chr12:22,285,377...22,389,008 JBrowse link
G Zcchc14 zinc finger CCHC-type containing 14 increases expression ISO quercitrin results in increased expression of ZCCHC14 mRNA CTD PMID:25193878 NCBI chr19:53,644,500...53,688,624
Ensembl chr19:53,647,815...53,688,597
JBrowse link
rocaglamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO rocaglamide results in increased expression of BAX protein CTD PMID:31433962 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO rocaglamide results in decreased expression of BCL2 protein CTD PMID:31433962 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex decreases expression ISO rocaglamide results in decreased expression of CHUK protein CTD PMID:31433962 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO rocaglamide results in increased expression of CYCS protein CTD PMID:31433962 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases expression ISO rocaglamide results in decreased expression of IKBKB protein CTD PMID:31433962 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO rocaglamide results in decreased expression of NFKB1 protein CTD PMID:31433962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO rocaglamide results in decreased expression of PARP1 protein CTD PMID:31433962 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression ISO rocaglamide results in decreased expression of RELA protein CTD PMID:31433962 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
sodium stibogluconate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Lovastatin results in decreased activity of ABCC1 protein] which results in increased susceptibility to Antimony Sodium Gluconate CTD PMID:18056276 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Antimony Sodium Gluconate results in decreased expression of BCL6 protein CTD PMID:27546522 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Antimony Sodium Gluconate results in decreased expression of CCL2 mRNA CTD PMID:20102417 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Epo erythropoietin decreases expression ISO Antimony Sodium Gluconate results in decreased expression of EPO mRNA; Antimony Sodium Gluconate results in decreased expression of EPO protein CTD PMID:9531339 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Icam1 intercellular adhesion molecule 1 affects response to substance ISO ICAM1 protein affects the susceptibility to Antimony Sodium Gluconate CTD PMID:11035738 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
affects response to substance
ISO Antimony Sodium Gluconate results in decreased expression of IFNG mRNA
[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL10 mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of NOS2 mRNA; IFNG protein affects the reaction [IL10RA protein affects the susceptibility to Antimony Sodium Gluconate]
IFNG protein affects the susceptibility to Antimony Sodium Gluconate
[Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein
CTD PMID:9234779, PMID:9498473, PMID:10603400, PMID:12870129, PMID:17911647, PMID:20102417 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Antimony Sodium Gluconate results in increased expression of IFNGR1 mRNA; Antimony Sodium Gluconate results in increased expression of IFNGR1 protein CTD PMID:12803856 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
affects response to substance
ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein
Antimony Sodium Gluconate results in decreased expression of IL10 mRNA
IL10 protein affects the susceptibility to Antimony Sodium Gluconate
[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL10 mRNA
CTD PMID:9234779, PMID:9498473, PMID:12379707, PMID:17911647, PMID:20102417 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha multiple interactions
affects response to substance
ISO IFNG protein affects the reaction [IL10RA protein affects the susceptibility to Antimony Sodium Gluconate] CTD PMID:12379707, PMID:12870129 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il12b interleukin 12B multiple interactions ISO [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA CTD PMID:9234779 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Antimony Sodium Gluconate results in decreased expression of IL1B mRNA CTD PMID:20102417 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
affects response to substance
ISO Antimony Sodium Gluconate results in decreased expression of IL4 mRNA
[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNA
IL4 protein affects the susceptibility to Antimony Sodium Gluconate
CTD PMID:7960131, PMID:9234779, PMID:11069076, PMID:20102417 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Antimony Sodium Gluconate results in increased expression of ITGAM protein CTD PMID:12399974 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of NOS2 mRNA CTD PMID:9234779 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 decreases activity ISO Antimony Sodium Gluconate results in decreased activity of PTPN6 protein CTD PMID:12399974 NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein CTD PMID:17911647 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Antimony Sodium Gluconate results in decreased expression of TNF mRNA CTD PMID:20102417 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 increases response to substance ISO TNFRSF18 protein results in increased susceptibility to Antimony Sodium Gluconate CTD PMID:20139272 NCBI chr 5:173,459,371...173,463,980
Ensembl chr 5:173,460,354...173,463,140
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Antimony Sodium Gluconate results in decreased expression of TNFRSF1A protein CTD PMID:7844400 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B decreases expression ISO Antimony Sodium Gluconate results in decreased expression of TNFRSF1B protein CTD PMID:7844400 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
Z-Val-Phe-H term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO calpain inhibitor III inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein] CTD PMID:16891617 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions EXP calpain inhibitor III inhibits the reaction [Isoflurane results in increased cleavage of and affects the localization of AIFM1 protein] CTD PMID:29289695 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Capn1 calpain 1 multiple interactions
decreases activity
ISO
EXP
calpain inhibitor III inhibits the reaction [CAPN1 protein results in increased susceptibility to Cisplatin]
calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]; calpain inhibitor III inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CAPN1 protein]; calpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN1 protein]; calpain inhibitor III inhibits the reaction [Manganese results in increased activity of CAPN1 protein]
calpain inhibitor III results in decreased activity of CAPN1 protein
CTD PMID:13678654, PMID:20878076, PMID:21985864, PMID:29289695 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 multiple interactions EXP calpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN2 protein] CTD PMID:29289695 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO calpain inhibitor III inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:16891617 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO calpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein] CTD PMID:19336499 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il1a interleukin 1 alpha affects localization ISO calpain inhibitor III affects the localization of IL1A protein CTD PMID:24024155 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Nefl neurofilament light multiple interactions EXP calpain inhibitor III inhibits the reaction [Zymosan results in increased degradation of NEFL protein] CTD PMID:15275793 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO calpain inhibitor III inhibits the reaction [Thioacetamide results in increased expression of NOS2 mRNA] CTD PMID:15316131 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 multiple interactions ISO
EXP
calpain inhibitor III inhibits the reaction [lactacystin results in increased cleavage of SPTAN1 protein]
calpain inhibitor III inhibits the reaction [Manganese results in increased cleavage of SPTAN1 protein]
CTD PMID:21683092, PMID:21985864 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO calpain inhibitor III inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA] CTD PMID:15316131 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        antimicrobial agent 17312
          antimicrobial drug 6206
            antiprotozoal drug 3817
              antileishmanial agent 330
                (-)-coronaridine + 0
                (S)-1'-methylbutyl caffeate 0
                (S)-1'-methyloctyl caffeate 0
                14-norpseurotin A 0
                2,2',4'-trihydroxy-6'-methoxy-3',5'-dimethylchalcone 0
                20-epi-isoiguesterinol 0
                22alpha-methoxy-3-beta-O-\{beta-D-Xylp(1->3)-[beta-D-Glcp-(1->2)]-beta-D-Glcp-(1->4)-beta-D-Glcp\}-furost-3beta,26-diol 26-O-beta-D-Glcp 0
                3-geranyl-2,4,6-trihydroxybenzophenone 0
                5,7,3',4'-tetrahydroxy-2'-(3,3-dimethylallyl)isoflavone 0
                5-O-methyl embelin 0
                7'-O-demethylisocephaeline 0
                GNF6702 0
                Z-Val-Phe-H 11
                acivicin 2
                acteoside 35
                ancistrotanzanine A 0
                ancistrotanzanine B 0
                ascaridole 2
                ciliatamide A 0
                ciliatamide B 0
                combretol 0
                dehydroemetine 0
                dihydrobetulinic acid 0
                flavokawain B 18
                geranylgeraniol + 25
                grandiflorenic acid 0
                guttiferone F 0
                hookerianamide J 0
                hookerianamide K 0
                isoiguesterin 0
                kavapyrone 0
                klugine 0
                methyl 3,4-dihydroxy-5-(3'-methyl-2'-butenyl)benzoate 0
                monastrol 0
                physalin F 0
                quercitrin 242
                ravuconazole 0
                rocaglamide 8
                rohitukine 0
                sodium stibogluconate 20
                tafenoquine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pharmaceutical 19275
          drug 19275
            antiinfective agent 13121
              antiparasitic agent 6072
                antiprotozoal drug 3817
                  antileishmanial agent 330
                    (-)-coronaridine + 0
                    (S)-1'-methylbutyl caffeate 0
                    (S)-1'-methyloctyl caffeate 0
                    14-norpseurotin A 0
                    2,2',4'-trihydroxy-6'-methoxy-3',5'-dimethylchalcone 0
                    20-epi-isoiguesterinol 0
                    22alpha-methoxy-3-beta-O-\{beta-D-Xylp(1->3)-[beta-D-Glcp-(1->2)]-beta-D-Glcp-(1->4)-beta-D-Glcp\}-furost-3beta,26-diol 26-O-beta-D-Glcp 0
                    3-geranyl-2,4,6-trihydroxybenzophenone 0
                    5,7,3',4'-tetrahydroxy-2'-(3,3-dimethylallyl)isoflavone 0
                    5-O-methyl embelin 0
                    7'-O-demethylisocephaeline 0
                    GNF6702 0
                    Z-Val-Phe-H 11
                    acivicin 2
                    acteoside 35
                    ancistrotanzanine A 0
                    ancistrotanzanine B 0
                    ascaridole 2
                    ciliatamide A 0
                    ciliatamide B 0
                    combretol 0
                    dehydroemetine 0
                    dihydrobetulinic acid 0
                    flavokawain B 18
                    geranylgeraniol + 25
                    grandiflorenic acid 0
                    guttiferone F 0
                    hookerianamide J 0
                    hookerianamide K 0
                    isoiguesterin 0
                    kavapyrone 0
                    klugine 0
                    methyl 3,4-dihydroxy-5-(3'-methyl-2'-butenyl)benzoate 0
                    monastrol 0
                    physalin F 0
                    quercitrin 242
                    ravuconazole 0
                    rocaglamide 8
                    rohitukine 0
                    sodium stibogluconate 20
                    tafenoquine 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.