Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:lurasidone hydrochloride
go back to main search page
Accession:CHEBI:70732 term browser browse the term
Definition:A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia.
Synonyms:exact_synonym: (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride
 related_synonym: 4-(1,2-benzothiazol-3-yl)-1-{[(1R,2R)-2-{[(3aR,4S,7R,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl]methyl}cyclohexyl]methyl}piperazin-1-ium chloride;   Formula=C28H37ClN4O2S;   InChI=1S/C28H36N4O2S.ClH/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26;/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2;1H/t18-,19+,20-,21-,24+,25-;/m0./s1;   InChIKey=NEKCRUIRPWNMLK-SCIYSFAVSA-N;   Latuda;   Lurasidone HCl;   SM 13496;   SMILES=Cl.[H][C@@]12[C@H]3CC[C@H](C3)[C@]1([H])C(=O)N(C[C@@H]1CCCC[C@H]1CN1CCN(CC1)c1nsc3ccccc13)C2=O;   lurasidone monohydrochloride
 xref: CAS:367514-88-3 "ChemIDplus";   CAS:367514-88-3 "KEGG DRUG";   KEGG:D04820
 xref_mesh: MESH:D000069056
 xref: PMID:21372761 "Europe PMC";   PMID:21446639 "Europe PMC";   PMID:21555300 "Europe PMC";   PMID:21935296 "Europe PMC";   PMID:22072817 "Europe PMC";   PMID:22545643 "Europe PMC";   PMID:22778856 "Europe PMC";   PMID:22828971 "Europe PMC";   Patent:EP1652848;   Reaxys:14540570 "Reaxys";   Wikipedia:Lurasidone_hydrochloride


show annotations for term's descendants       view all columns           Sort by:
 
lurasidone hydrochloride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    chemical entity 19726
      molecular entity 19723
        ion 15808
          organic ion 7895
            organic cation 7115
              lurasidone(1+) 3
                lurasidone hydrochloride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      halogen 17756
                        chlorine atom 17493
                          chlorine molecular entity 17493
                            elemental chlorine 8368
                              monoatomic chlorine 8349
                                chloride 8349
                                  chloride salt 8349
                                    organic chloride salt 652
                                      hydrochloride 427
                                        lurasidone hydrochloride 3
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.