CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Narciclasine
Accession: CHEBI:70169
browse the term
Definition: A phenanthridine that has formula C14H13NO7.
Synonyms: related_synonym: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one; Formula=C14H13NO7; InChI=1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1; InChIKey=LZAZURSABQIKGB-AEKGRLRDSA-N; Lycoricidin-A; Lycoricidinol; SMILES=[H][C@@]12NC(=O)c3c(O)c4OCOc4cc3C1=C[C@H](O)[C@@H](O)[C@H]2O
alt_id: CHEBI:7481
xref: CAS:29477-83-6; KEGG:C08533; KNApSAcK:C00001577; LINCS:LSM-4934
xref_mesh: MESH:C010753
xref: PMID:21105682
G
Il6
interleukin 6
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD
PMID:30738987
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
CTD
PMID:30738987
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides results in increased degradation of and results in increased phosphorylation of NFKBIA protein]
CTD
PMID:30738987
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nos2
nitric oxide synthase 2
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
CTD
PMID:30738987
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD
PMID:30738987
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of RELA protein]
CTD
PMID:30738987
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Tnf
tumor necrosis factor
multiple interactions
ISO
narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD
PMID:30738987
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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