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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Narciclasine
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Accession:CHEBI:70169 term browser browse the term
Definition:A phenanthridine that has formula C14H13NO7.
Synonyms:related_synonym: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one;   Formula=C14H13NO7;   InChI=1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1;   InChIKey=LZAZURSABQIKGB-AEKGRLRDSA-N;   Lycoricidin-A;   Lycoricidinol;   SMILES=[H][C@@]12NC(=O)c3c(O)c4OCOc4cc3C1=C[C@H](O)[C@@H](O)[C@H]2O
 alt_id: CHEBI:7481
 xref: CAS:29477-83-6;   KEGG:C08533;   KNApSAcK:C00001577;   LINCS:LSM-4934
 xref_mesh: MESH:C010753
 xref: PMID:21105682


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Narciclasine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:30738987 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:30738987 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased degradation of and results in increased phosphorylation of NFKBIA protein] CTD PMID:30738987 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:30738987 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:30738987 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of RELA protein] CTD PMID:30738987 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:30738987 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        biochemical role 19311
          metabolite 19293
            Narciclasine 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic molecule 19505
                              organic cyclic compound 19332
                                organic heterocyclic compound 18519
                                  organic heteropolycyclic compound 17979
                                    organic heterotricyclic compound 14602
                                      dibenzopyridine 155
                                        phenanthridines 51
                                          Narciclasine 7
paths to the root