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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Narciclasine
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Accession:CHEBI:70169 term browser browse the term
Definition:A phenanthridine that has formula C14H13NO7.
Synonyms:related_synonym: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one;   Formula=C14H13NO7;   InChI=1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1;   InChIKey=LZAZURSABQIKGB-AEKGRLRDSA-N;   Lycoricidin-A;   Lycoricidinol;   SMILES=[H][C@@]12NC(=O)c3c(O)c4OCOc4cc3C1=C[C@H](O)[C@@H](O)[C@H]2O
 alt_id: CHEBI:7481
 xref: CAS:29477-83-6;   KEGG:C08533;   KNApSAcK:C00001577;   LINCS:LSM-4934
 xref_mesh: MESH:C010753
 xref: PMID:21105682



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Narciclasine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:30738987 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:30738987 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased degradation of and results in increased phosphorylation of NFKBIA protein] CTD PMID:30738987 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:30738987 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:30738987 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of RELA protein] CTD PMID:30738987 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO narciclasine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:30738987 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            Narciclasine 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteropolycyclic compound 18043
                                    organic heterotricyclic compound 14639
                                      dibenzopyridine 154
                                        phenanthridines 51
                                          Narciclasine 7
paths to the root