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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(+)-(S)-ar-turmerone
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Accession:CHEBI:70159 term browser browse the term
Definition:A sesquiterpenoid that is 2-methylhept-2-en-4-one substituted by a 4-methylphenyl group at position 6. It has been isolated from Peltophorum dasyrachis.
Synonyms:related_synonym: (6S)-2-methyl-6-(4-methylphenyl)hept-2-en-4-one;   Formula=C15H20O;   InChI=1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9,13H,10H2,1-4H3/t13-/m0/s1;   InChIKey=NAAJVHHFAXWBOK-ZDUSSCGKSA-N;   SMILES=C[C@@H](CC(=O)C=C(C)C)c1ccc(C)cc1
 xref: CAS:532-65-0
 xref_mesh: MESH:C078098
 xref: PMID:21189039;   Reaxys:3606512


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(+)-(S)-ar-turmerone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO ar-turmerone results in increased expression of ABCB1 mRNA CTD PMID:22181075 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
ISO ar-turmerone results in increased activity of AHR protein
ar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD PMID:29191726 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO ar-turmerone results in increased expression of BAX mRNA; ar-turmerone results in increased expression of BAX protein CTD PMID:19250610 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Casp3 caspase 3 increases activity ISO ar-turmerone results in increased activity of CASP3 protein CTD PMID:19250610 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO ar-turmerone results in increased expression of CYP1A1 mRNA
ar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:29191726 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO ar-turmerone binds to PPARG protein CTD PMID:15713005 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Tp53 tumor protein p53 increases expression ISO ar-turmerone results in increased expression of TP53 mRNA; ar-turmerone results in increased expression of TP53 protein CTD PMID:19250610 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              plant metabolite 17360
                (+)-(S)-ar-turmerone 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      ketone 16144
                                        alpha,beta-unsaturated ketone 8520
                                          enone 8520
                                            (+)-(S)-ar-turmerone 7
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