Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(+)-(S)-ar-turmerone
go back to main search page
Accession:CHEBI:70159 term browser browse the term
Definition:A sesquiterpenoid that is 2-methylhept-2-en-4-one substituted by a 4-methylphenyl group at position 6. It has been isolated from Peltophorum dasyrachis.
Synonyms:related_synonym: (6S)-2-methyl-6-(4-methylphenyl)hept-2-en-4-one;   Formula=C15H20O;   InChI=1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9,13H,10H2,1-4H3/t13-/m0/s1;   InChIKey=NAAJVHHFAXWBOK-ZDUSSCGKSA-N;   SMILES=C[C@@H](CC(=O)C=C(C)C)c1ccc(C)cc1
 xref: CAS:532-65-0
 xref_mesh: MESH:C078098
 xref: PMID:21189039;   Reaxys:3606512



show annotations for term's descendants           Sort by:
 
(+)-(S)-ar-turmerone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO ar-turmerone results in increased expression of ABCB1 mRNA CTD PMID:22181075 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
ISO ar-turmerone results in increased activity of AHR protein
ar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]
CTD PMID:29191726 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO ar-turmerone results in increased expression of BAX mRNA; ar-turmerone results in increased expression of BAX protein CTD PMID:19250610 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Casp3 caspase 3 increases activity ISO ar-turmerone results in increased activity of CASP3 protein CTD PMID:19250610 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO ar-turmerone results in increased expression of CYP1A1 mRNA
ar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:29191726 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO ar-turmerone binds to PPARG protein CTD PMID:15713005 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Tp53 tumor protein p53 increases expression ISO ar-turmerone results in increased expression of TP53 mRNA; ar-turmerone results in increased expression of TP53 protein CTD PMID:19250610 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19763
      biological role 19763
        biochemical role 19380
          metabolite 19358
            eukaryotic metabolite 19046
              plant metabolite 17459
                (+)-(S)-ar-turmerone 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      carbon group element atom 19631
                        carbon atom 19621
                          organic molecular entity 19621
                            organic group 18730
                              organic divalent group 18721
                                organodiyl group 18721
                                  carbonyl group 18670
                                    carbonyl compound 18670
                                      ketone 16930
                                        alpha,beta-unsaturated ketone 9273
                                          enone 9273
                                            (+)-(S)-ar-turmerone 7
paths to the root