Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Ilimaquinone
go back to main search page
Accession:CHEBI:70133 term browser browse the term
Definition:A prenylquinone that has formula C22H30O4.
Synonyms:related_synonym: 3-[[(1R,2S,4aS,8aS)-1,2,4a-trimethyl-5-methylidene-3,4,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl]-2-hydroxy-5-methoxycyclohexa-2,5-diene-1,4-dione;   Formula=C22H30O4;   InChI=1S/C22H30O4/c1-13-7-6-8-18-21(13,3)10-9-14(2)22(18,4)12-15-19(24)16(23)11-17(26-5)20(15)25/h11,14,18,24H,1,6-10,12H2,2-5H3/t14-,18+,21+,22+/m0/s1;   InChIKey=JJWITJNSXCXULM-YVUMSICPSA-N;   SMILES=[H][C@@]12CCCC(=C)[C@@]1(C)CC[C@H](C)[C@@]2(C)CC1=C(O)C(=O)C=C(OC)C1=O
 alt_id: MESH:C467077
 xref: CAS:71678-03-0
 xref_mesh: MESH:C467077
 xref: PMID:21155589


show annotations for term's descendants           Sort by:
 
Ilimaquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO ilimaquinone results in decreased expression of BCL2 protein CTD PMID:24930757 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO ilimaquinone results in decreased expression of BCL2L1 protein CTD PMID:24930757 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO [ilimaquinone results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; ilimaquinone promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]
ilimaquinone results in increased cleavage of CASP3 protein
CTD PMID:24930757 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage ISO ilimaquinone results in increased cleavage of CASP8 protein CTD PMID:24930757 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ilimaquinone results in increased expression of DDIT3 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [ilimaquinone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of DDIT3 mRNA] CTD PMID:24930757 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO ilimaquinone results in increased phosphorylation of MAPK1 protein CTD PMID:24930757 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO ilimaquinone results in increased phosphorylation of MAPK3 protein CTD PMID:24930757 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [ilimaquinone results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of PARP1 protein; ilimaquinone promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]
ilimaquinone results in increased cleavage of PARP1 protein
CTD PMID:24930757 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pld2 phospholipase D2 multiple interactions
increases activity
ISO 1-Butanol inhibits the reaction [ilimaquinone results in increased activity of PLD2 protein] CTD PMID:17897952 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]
ilimaquinone results in increased expression of TNFRSF10A mRNA; ilimaquinone results in increased expression of TNFRSF10A protein
CTD PMID:24930757 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [ilimaquinone results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; [ilimaquinone results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of PARP1 protein; ilimaquinone promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; ilimaquinone promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:24930757 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          metabolite 19285
            Ilimaquinone 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      ketone 16171
                                        cyclic ketone 13874
                                          quinone 8341
                                            benzoquinones 716
                                              1,4-benzoquinones 712
                                                monohydroxy-1,4-benzoquinones 66
                                                  Ilimaquinone 11
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.