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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:moricizine
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Accession:CHEBI:6997 term browser browse the term
Definition:A phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group.
Synonyms:exact_synonym: ethyl {10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate
 related_synonym: EN-313;   Formula=C22H25N3O4S;   InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27);   InChIKey=FUBVWMNBEHXPSU-UHFFFAOYSA-N;   SMILES=CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN3CCOCC3)c2c1;   [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester;   ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate;   ethyl 10-(beta-N-morpholinylpropionyl)phenothiazine-2-carbamate;   moracizina;   moracizine;   moracizinum
 alt_id: CHEBI:239866
 xref: CAS:31883-05-3;   DrugBank:DB00680;   Drug_Central:1842;   KEGG:C07743;   KEGG:D05077;   LINCS:LSM-2476
 xref_mesh: MESH:D016293
 xref: Patent:DE2014201;   Patent:US3740395;   Reaxys:592021;   Wikipedia:Moricizine


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moricizine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Moricizine results in increased expression of CYP2B6 mRNA CTD PMID:18332078 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pharmaceutical 19293
          drug 19293
            cardiovascular drug 7618
              anti-arrhythmia drug 915
                moricizine 1
                  moricizine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      carboxylic ester 14367
                                        carbamate ester 7387
                                          moricizine 1
                                            moricizine hydrochloride 0
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