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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:moricizine
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Accession:CHEBI:6997 term browser browse the term
Definition:A phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group.
Synonyms:exact_synonym: ethyl {10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate
 related_synonym: EN-313;   Formula=C22H25N3O4S;   InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27);   InChIKey=FUBVWMNBEHXPSU-UHFFFAOYSA-N;   SMILES=CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN3CCOCC3)c2c1;   [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester;   ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate;   ethyl 10-(beta-N-morpholinylpropionyl)phenothiazine-2-carbamate;   moracizina;   moracizine;   moracizinum
 alt_id: CHEBI:239866
 xref: CAS:31883-05-3;   DrugBank:DB00680;   Drug_Central:1842;   KEGG:C07743;   KEGG:D05077;   LINCS:LSM-2476
 xref_mesh: MESH:D016293
 xref: Patent:DE2014201;   Patent:US3740395;   Reaxys:592021;   Wikipedia:Moricizine



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moricizine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Moricizine results in increased expression of CYP2B6 mRNA CTD PMID:18332078 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Moricizine results in increased expression of CYP3A4 mRNA CTD PMID:18332078 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    role 19713
      application 19546
        pharmaceutical 19425
          drug 19425
            cardiovascular drug 8454
              anti-arrhythmia drug 1493
                moricizine 2
                  moricizine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18798
                                    carbonyl compound 18798
                                      carboxylic ester 15962
                                        carbamate ester 7479
                                          moricizine 2
                                            moricizine hydrochloride 0
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