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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:moricizine
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Accession:CHEBI:6997 term browser browse the term
Definition:A phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group.
Synonyms:exact_synonym: ethyl {10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate
 related_synonym: EN-313;   Formula=C22H25N3O4S;   InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27);   InChIKey=FUBVWMNBEHXPSU-UHFFFAOYSA-N;   SMILES=CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN3CCOCC3)c2c1;   [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester;   ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate;   ethyl 10-(beta-N-morpholinylpropionyl)phenothiazine-2-carbamate;   moracizina;   moracizine;   moracizinum
 alt_id: CHEBI:239866
 xref: CAS:31883-05-3;   DrugBank:DB00680;   Drug_Central:1842;   KEGG:C07743;   KEGG:D05077;   LINCS:LSM-2476
 xref_mesh: MESH:D016293
 xref: Patent:DE2014201;   Patent:US3740395;   Reaxys:592021;   Wikipedia:Moricizine


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moricizine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Moricizine results in increased expression of CYP2B6 mRNA CTD PMID:18332078 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Moricizine results in increased expression of CYP3A4 mRNA CTD PMID:18332078 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        pharmaceutical 19329
          drug 19329
            cardiovascular drug 7683
              anti-arrhythmia drug 956
                moricizine 2
                  moricizine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic ester 15884
                                        carbamate ester 7445
                                          moricizine 2
                                            moricizine hydrochloride 0
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