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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:14-Deoxy-11,12-didehydroandrographolide
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Accession:CHEBI:69808 term browser browse the term
Definition:A diterpene lactone that has formula C20H28O4.
Synonyms:related_synonym: 3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone;   Formula=C20H28O4;   InChI=1S/C20H28O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h5-6,9,15-17,21-22H,1,4,7-8,10-12H2,2-3H3/b6-5+/t15-,16+,17-,19+,20+/m1/s1;   InChIKey=XMJAJFVLHDIEHF-CRBRZBHVSA-N;   SMILES=[H][C@]12CCC(=C)[C@@H](\\C=C\\C3=CCOC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO
 xref_mesh: MESH:C495626
 xref: PMID:21598983


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14-Deoxy-11,12-didehydroandrographolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AAAS mRNA CTD PMID:22101062 NCBI chr 7:143,937,198...143,956,668
Ensembl chr 7:143,937,199...143,956,668
JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ACP2 mRNA CTD PMID:22101062 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Adrm1 adhesion regulating molecule 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ADRM1 mRNA CTD PMID:22101062 NCBI chr 3:175,548,181...175,552,943
Ensembl chr 3:175,548,174...175,552,947
JBrowse link
G Ajuba ajuba LIM protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AJUBA mRNA CTD PMID:22101062 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AK1 mRNA CTD PMID:22101062 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akap1 A-kinase anchoring protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AKAP1 mRNA CTD PMID:22101062 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AKR7A2 mRNA CTD PMID:22101062 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ALDOA mRNA CTD PMID:22101062 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Ank3 ankyrin 3 decreases expression
increases expression
ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ANK3 mRNA
14-deoxy-11,12-didehydroandrographolide results in increased expression of ANK3 mRNA
CTD PMID:22101062 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ARHGAP5 mRNA CTD PMID:22101062 NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
JBrowse link
G Arid4a AT-rich interaction domain 4A increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of ARID4A mRNA CTD PMID:22101062 NCBI chr 6:93,461,713...93,532,901
Ensembl chr 6:93,461,713...93,532,901
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ARIH2 mRNA CTD PMID:22101062 NCBI chr 8:117,387,004...117,446,085
Ensembl chr 8:117,387,010...117,446,019
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ASXL1 mRNA CTD PMID:22101062 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ATP5F1D mRNA CTD PMID:22101062 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ATP6V0D1 mRNA CTD PMID:22101062 NCBI chr19:37,481,782...37,525,762
Ensembl chr19:37,481,782...37,525,762
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ATP6V1C1 mRNA CTD PMID:22101062 NCBI chr 7:77,678,853...77,716,658
Ensembl chr 7:77,678,968...77,716,408
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of BAG1 mRNA CTD PMID:22101062 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of BCLAF1 mRNA CTD PMID:22101062 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Bloc1s1 biogenesis of lysosomal organelles complex-1, subunit 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of BLOC1S1 mRNA CTD PMID:22101062 NCBI chr 7:3,342,630...3,346,238
Ensembl chr 7:3,342,630...3,346,238
JBrowse link
G Ca12 carbonic anhydrase 12 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CA12 mRNA CTD PMID:22101062 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CAPRIN1 mRNA CTD PMID:22101062 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] CTD PMID:27089844 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:27089844 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnb1ip1 cyclin B1 interacting protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CCNB1IP1 mRNA CTD PMID:22101062 NCBI chr15:27,720,220...27,736,528
Ensembl chr15:27,720,223...27,733,785
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CCND1 mRNA
14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCND1 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CCND1 protein]]
CTD PMID:22101062, PMID:30248417 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CCND3 mRNA CTD PMID:22101062 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNE1 protein] CTD PMID:30248417 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccng2 cyclin G2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CCNG2 mRNA CTD PMID:22101062 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CDC37 mRNA CTD PMID:22101062 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CDK2 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CDK2 protein]] CTD PMID:30248417 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CDK6 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CDK6 protein]] CTD PMID:30248417 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CDKN1B mRNA CTD PMID:22101062 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] promotes the reaction [CREB1 protein binds to CEBPB promoter]]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPB mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CEBPB protein] CTD PMID:30248417 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cenps centromere protein S decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CENPS mRNA CTD PMID:22101062 NCBI chr 5:165,946,106...165,955,723 JBrowse link
G Cfl1 cofilin 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CFL1 mRNA CTD PMID:22101062 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CHD2 mRNA CTD PMID:22101062 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CHTF8 mRNA CTD PMID:22101062 NCBI chr19:39,077,580...39,087,880
Ensembl chr19:39,077,580...39,087,880
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CLPTM1 mRNA CTD PMID:22101062 NCBI chr 1:80,549,051...80,580,665
Ensembl chr 1:80,549,043...80,580,662
JBrowse link
G Cope COPI coat complex subunit epsilon decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of COPE mRNA CTD PMID:22101062 NCBI chr16:20,863,141...20,873,516
Ensembl chr16:20,863,141...20,873,521
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] promotes the reaction [CREB1 protein binds to CEBPB promoter]]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CREB1 protein] CTD PMID:30248417 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CXCL12 mRNA CTD PMID:22101062 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CYP1A1 mRNA
beta-Naphthoflavone promotes the reaction [14-deoxy-11,12-didehydroandrographolide results in increased expression of CYP1A1 mRNA]
CTD PMID:21963808 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DCAF6 mRNA CTD PMID:22101062 NCBI chr13:83,578,730...83,680,330
Ensembl chr13:83,579,036...83,680,207
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of DDIT3 mRNA CTD PMID:22101062 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of DDIT4 mRNA CTD PMID:22101062 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DHFR mRNA CTD PMID:22101062 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Drg2 developmentally regulated GTP binding protein 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DRG2 mRNA CTD PMID:22101062 NCBI chr10:46,818,412...46,831,308
Ensembl chr10:46,818,525...46,830,739
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DUT mRNA CTD PMID:22101062 NCBI chr 3:117,514,399...117,525,450
Ensembl chr 3:117,514,444...117,525,446
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of EIF4EBP1 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of EIF4EBP1 protein]] CTD PMID:30248417 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of ELOVL2 mRNA CTD PMID:22101062 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G Eno1 enolase 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ENO1 mRNA CTD PMID:22101062 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of EWSR1 mRNA CTD PMID:22101062 NCBI chr14:85,322,105...85,350,826
Ensembl chr14:85,322,296...85,350,948
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein] CTD PMID:30248417 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo8 F-box protein 8 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FBXO8 mRNA CTD PMID:22101062 NCBI chr16:37,131,566...37,177,033
Ensembl chr16:37,131,345...37,177,033
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FEN1 mRNA CTD PMID:22101062 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Fibp FGF1 intracellular binding protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FIBP mRNA CTD PMID:22101062 NCBI chr 1:220,840,078...220,844,412
Ensembl chr 1:220,840,118...220,844,405
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FKBP1A mRNA CTD PMID:22101062 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Flcn folliculin increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FLCN mRNA CTD PMID:22101062 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Fnip1 folliculin interacting protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FNIP1 mRNA CTD PMID:22101062 NCBI chr10:39,786,687...39,870,188 JBrowse link
G Folr1 folate receptor alpha increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FOLR1 mRNA CTD PMID:22101062 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Fus FUS RNA binding protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FUS mRNA CTD PMID:22101062 NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702
JBrowse link
G Fzd7 frizzled class receptor 7 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FZD7 mRNA CTD PMID:22101062 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GADD45A mRNA CTD PMID:22101062 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gas5 growth arrest specific 5 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GAS5 mRNA CTD PMID:22101062 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gfus GDP-L-fucose synthase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GFUS mRNA CTD PMID:22101062 NCBI chr 7:116,958,427...116,963,281
Ensembl chr 7:116,958,392...116,963,295
JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GNE mRNA CTD PMID:22101062 NCBI chr 5:59,511,738...59,553,421
Ensembl chr 5:59,512,872...59,553,416
JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GPAA1 mRNA CTD PMID:22101062 NCBI chr 7:117,394,367...117,397,950
Ensembl chr 7:117,394,372...117,397,956
JBrowse link
G Gps1 G protein pathway suppressor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GPS1 mRNA CTD PMID:22101062 NCBI chr10:109,966,875...109,971,912
Ensembl chr10:109,966,904...109,971,911
JBrowse link
G Gps2 G protein pathway suppressor 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GPS2 mRNA CTD PMID:22101062 NCBI chr10:56,524,327...56,527,447
Ensembl chr10:56,524,468...56,526,987
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein] CTD PMID:30248417 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gulp1 GULP PTB domain containing engulfment adaptor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GULP1 mRNA CTD PMID:22101062 NCBI chr 9:51,263,484...51,538,066
Ensembl chr 9:51,263,622...51,538,072
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of H1-2 mRNA CTD PMID:22101062 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H2bc9 H2B clustered histone 9 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of H2BC9 mRNA CTD PMID:22101062 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HBP1 mRNA CTD PMID:22101062 NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625
JBrowse link
G Hells helicase, lymphoid specific decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HELLS mRNA CTD PMID:22101062 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HERPUD1 mRNA CTD PMID:22101062 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HGSNAT mRNA CTD PMID:22101062 NCBI chr16:70,876,557...70,909,443 JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HMGCS2 mRNA CTD PMID:22101062 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HNRNPA1 mRNA CTD PMID:22101062 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HNRNPD mRNA CTD PMID:22101062 NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578
JBrowse link
G Hoxb3 homeo box B3 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HOXB3 mRNA CTD PMID:22101062 NCBI chr10:84,170,629...84,196,823
Ensembl chr10:84,182,118...84,195,796
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of IFRD1 mRNA CTD PMID:22101062 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of IFRD2 mRNA CTD PMID:22101062 NCBI chr 8:116,343,096...116,348,318
Ensembl chr 8:116,343,096...116,348,314
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of IGFBP5 mRNA CTD PMID:22101062 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27089844 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of IMMP1L mRNA CTD PMID:22101062 NCBI chr 3:95,955,126...96,024,316
Ensembl chr 3:95,959,703...96,024,836
JBrowse link
G Ints11 integrator complex subunit 11 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of INTS11 mRNA CTD PMID:22101062 NCBI chr 5:173,318,435...173,336,930
Ensembl chr 5:173,318,479...173,336,930
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ITGB1BP1 mRNA CTD PMID:22101062 NCBI chr 6:43,348,927...43,363,633
Ensembl chr 6:43,348,958...43,363,335
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ITPK1 mRNA CTD PMID:22101062 NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of JMY mRNA CTD PMID:22101062 NCBI chr 2:23,026,506...23,097,702
Ensembl chr 2:23,042,189...23,097,610
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of KCNK2 mRNA CTD PMID:22101062 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of LGR4 mRNA CTD PMID:22101062 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lhx2 LIM homeobox 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of LHX2 mRNA CTD PMID:22101062 NCBI chr 3:22,628,674...22,658,447
Ensembl chr 3:22,640,545...22,658,446
JBrowse link
G Lmna lamin A/C decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of LMNA mRNA CTD PMID:22101062 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of H2AC6 mRNA CTD PMID:22101062 NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of LRRN3 mRNA CTD PMID:22101062 NCBI chr 6:61,374,328...61,405,195
Ensembl chr 6:61,374,328...61,405,195
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of LSR mRNA CTD PMID:22101062 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MANF mRNA CTD PMID:22101062 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK1 protein] CTD PMID:30248417 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk13 mitogen activated protein kinase 13 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MAPK13 mRNA CTD PMID:22101062 NCBI chr20:6,018,374...6,027,467
Ensembl chr20:6,018,374...6,027,473
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:30248417 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MCL1 mRNA CTD PMID:22101062 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MCM2 mRNA CTD PMID:22101062 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MCM3 mRNA CTD PMID:22101062 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Msto1 misato mitochondrial distribution and morphology regulator 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MSTO1 mRNA CTD PMID:22101062 NCBI chr 2:188,212,211...188,216,482
Ensembl chr 2:188,212,211...188,216,482
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MTSS1 mRNA CTD PMID:22101062 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MXI1 mRNA CTD PMID:22101062 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MYBL2 mRNA CTD PMID:22101062 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MYC mRNA CTD PMID:22101062 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nabp2 nucleic acid binding protein 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of NABP2 mRNA CTD PMID:22101062 NCBI chr 7:2,820,006...2,825,627
Ensembl chr 7:2,820,007...2,825,608
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NAMPT mRNA CTD PMID:22101062 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of NBL1 mRNA CTD PMID:22101062 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
G Nck1 NCK adaptor protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NCK1 mRNA CTD PMID:22101062 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NFAT5 mRNA CTD PMID:22101062 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nmu neuromedin U decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of NMU mRNA CTD PMID:22101062 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NUPR1 mRNA CTD PMID:22101062 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Olfm1 olfactomedin 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of OLFM1 mRNA CTD PMID:22101062 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PAFAH1B1 mRNA CTD PMID:22101062 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
G Pkm pyruvate kinase M1/2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PKM mRNA CTD PMID:22101062 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Plxnb2 plexin B2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PLXNB2 mRNA CTD PMID:22101062 NCBI chr 7:130,135,484...130,161,568
Ensembl chr 7:130,135,464...130,151,880
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of POLA1 mRNA CTD PMID:22101062 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] CTD PMID:30248417 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PPFIA1 mRNA CTD PMID:22101062 NCBI chr 1:217,644,259...217,721,285
Ensembl chr 1:217,644,224...217,721,376
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PPP1CA mRNA CTD PMID:22101062 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Prcp prolylcarboxypeptidase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PRCP mRNA CTD PMID:22101062 NCBI chr 1:157,701,089...157,750,177
Ensembl chr 1:157,701,089...157,750,169
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of PRKACA protein] CTD PMID:30248417 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkcsh protein kinase C substrate 80K-H decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PRKCSH mRNA CTD PMID:22101062 NCBI chr 8:23,014,802...23,026,507
Ensembl chr 8:23,014,956...23,026,503
JBrowse link
G Prlr prolactin receptor increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PRLR mRNA CTD PMID:22101062 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Prrg4 proline rich and Gla domain 4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PRRG4 mRNA CTD PMID:22101062 NCBI chr 3:94,783,866...94,808,861
Ensembl chr 3:94,784,008...94,808,861
JBrowse link
G Psen2 presenilin 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PSEN2 mRNA CTD PMID:22101062 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PSMC3 mRNA CTD PMID:22101062 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PSPC1 mRNA CTD PMID:22101062 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Ptprk protein tyrosine phosphatase, receptor type, K increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PTPRK mRNA CTD PMID:22101062 NCBI chr 1:17,445,052...18,058,266
Ensembl chr 1:17,446,417...18,058,055
JBrowse link
G Rab27b RAB27B, member RAS oncogene family increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RAB27B mRNA CTD PMID:22101062 NCBI chr18:68,486,006...68,644,595
Ensembl chr18:68,488,942...68,551,558
JBrowse link
G Rangap1 RAN GTPase activating protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RANGAP1 mRNA CTD PMID:22101062 NCBI chr 7:122,939,266...122,967,178
Ensembl chr 7:122,940,376...122,967,178
JBrowse link
G Rbm10 RNA binding motif protein 10 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RBM10 mRNA CTD PMID:22101062 NCBI chr  X:1,754,869...1,786,973
Ensembl chr  X:1,754,861...1,786,978
JBrowse link
G Rbm47 RNA binding motif protein 47 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RBM47 mRNA CTD PMID:22101062 NCBI chr14:43,701,944...43,839,803
Ensembl chr14:43,810,119...43,837,662
JBrowse link
G Rcbtb1 RCC1 and BTB domain containing protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RCBTB1 mRNA CTD PMID:22101062 NCBI chr15:39,622,572...39,665,335
Ensembl chr15:39,638,510...39,669,473
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased activity of and affects the localization of RELA protein] CTD PMID:27089844 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RFFL mRNA CTD PMID:22101062 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G Rhod ras homolog family member D decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RHOD mRNA CTD PMID:22101062 NCBI chr 1:219,668,352...219,682,287
Ensembl chr 1:219,668,352...219,682,287
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RIT1 mRNA CTD PMID:22101062 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RORC mRNA CTD PMID:22101062 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPS6KB1 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:30248417 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions ISO [14-deoxy-11,12-didehydroandrographolide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPTOR protein; dorsomorphin inhibits the reaction [[14-deoxy-11,12-didehydroandrographolide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPTOR protein] CTD PMID:30248417 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691
JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RSRC2 mRNA CTD PMID:22101062 NCBI chr12:38,274,290...38,294,294
Ensembl chr12:38,274,297...38,294,292
JBrowse link
G Rtkn rhotekin decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RTKN mRNA CTD PMID:22101062 NCBI chr 4:114,833,453...114,850,705
Ensembl chr 4:114,835,064...114,850,701
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SCARB1 mRNA CTD PMID:22101062 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SCD1 mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SCD1 protein] CTD PMID:30248417 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SEL1L mRNA CTD PMID:22101062 NCBI chr 6:115,572,683...115,616,904
Ensembl chr 6:115,572,649...115,616,859
JBrowse link
G Sertad2 SERTA domain containing 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SERTAD2 mRNA CTD PMID:22101062 NCBI chr14:104,786,649...104,890,022
Ensembl chr14:104,821,215...104,886,197
JBrowse link
G Sf1 splicing factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SF1 mRNA CTD PMID:22101062 NCBI chr 1:221,735,512...221,749,216
Ensembl chr 1:221,735,517...221,749,086
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFPQ mRNA CTD PMID:22101062 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sfxn2 sideroflexin 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFXN2 mRNA CTD PMID:22101062 NCBI chr 1:266,333,440...266,345,736
Ensembl chr 1:266,333,440...266,345,697
JBrowse link
G Sfxn4 sideroflexin 4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFXN4 mRNA CTD PMID:22101062 NCBI chr 1:282,213,610...282,236,851
Ensembl chr 1:282,213,675...282,235,974
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SIGMAR1 mRNA CTD PMID:22101062 NCBI chr 5:58,121,824...58,124,687
Ensembl chr 5:58,121,786...58,124,681
JBrowse link
G Slc35a4 solute carrier family 35, member A4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLC35A4 mRNA CTD PMID:22101062 NCBI chr18:29,505,239...29,509,304
Ensembl chr18:29,506,128...29,509,296
JBrowse link
G Slc39a3 solute carrier family 39 member 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLC39A3 mRNA CTD PMID:22101062 NCBI chr 7:11,545,073...11,551,074
Ensembl chr 7:11,545,024...11,553,370
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLC9A3R1 mRNA CTD PMID:22101062 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Slitrk4 SLIT and NTRK-like family, member 4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLITRK4 mRNA CTD PMID:22101062 NCBI chr  X:147,582,195...147,589,529 JBrowse link
G Snf8 SNF8 subunit of ESCRT-II decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SNF8 mRNA CTD PMID:22101062 NCBI chr10:83,856,331...83,868,621
Ensembl chr10:83,856,280...83,868,598
JBrowse link
G Snx16 sorting nexin 16 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SNX16 mRNA CTD PMID:22101062 NCBI chr 2:93,518,796...93,541,056
Ensembl chr 2:93,518,806...93,540,328
JBrowse link
G Sowahc sosondowah ankyrin repeat domain family member C increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SOWAHC mRNA CTD PMID:22101062 NCBI chr20:28,815,039...28,819,505
Ensembl chr20:28,815,039...28,819,505
JBrowse link
G Spire1 spire-type actin nucleation factor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SPIRE1 mRNA CTD PMID:22101062 NCBI chr18:63,226,557...63,357,420
Ensembl chr18:63,226,557...63,357,298
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SREBF1 mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SREBF1 protein] CTD PMID:30248417 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srm spermidine synthase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRM mRNA CTD PMID:22101062 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
G Srpk2 SRSF protein kinase 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SRPK2 mRNA CTD PMID:22101062 NCBI chr 4:7,994,025...8,187,455
Ensembl chr 4:8,066,737...8,185,935
JBrowse link
G Srrt serrate, RNA effector molecule decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRRT mRNA CTD PMID:22101062 NCBI chr12:22,457,898...22,471,090 JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRSF1 mRNA CTD PMID:22101062 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRSF2 mRNA CTD PMID:22101062 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFRS3 mRNA CTD PMID:22101062 NCBI chr20:6,288,285...6,298,218
Ensembl chr20:6,288,267...6,298,213
JBrowse link
G Stard10 StAR-related lipid transfer domain containing 10 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of STARD10 mRNA CTD PMID:22101062 NCBI chr 1:166,428,780...166,458,413
Ensembl chr 1:166,428,761...166,457,509
JBrowse link
G Stx3 syntaxin 3 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of STX3 mRNA CTD PMID:22101062 NCBI chr 1:228,137,781...228,195,004
Ensembl chr 1:228,149,867...228,194,977
JBrowse link
G Tbrg1 transforming growth factor beta regulator 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of TBRG1 mRNA CTD PMID:22101062 NCBI chr 8:40,114,792...40,122,450
Ensembl chr 8:40,114,792...40,122,450
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TCAF1 mRNA CTD PMID:22101062 NCBI chr 4:72,119,349...72,171,733
Ensembl chr 4:72,124,234...72,143,748
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of TFAP2A mRNA CTD PMID:22101062 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of TFF1 mRNA CTD PMID:22101062 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of THSD4 mRNA CTD PMID:22101062 NCBI chr 8:64,811,940...65,413,498
Ensembl chr 8:64,817,191...65,003,296
JBrowse link
G Tipin timeless interacting protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TIPIN mRNA CTD PMID:22101062 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305
JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TK1 mRNA CTD PMID:22101062 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased activity of and affects the localization of RELA protein]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27089844 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TP53I3 mRNA CTD PMID:22101062 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Trak2 trafficking kinesin protein 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TRAK2 mRNA CTD PMID:22101062 NCBI chr 9:65,698,706...65,763,351
Ensembl chr 9:65,698,712...65,763,273
JBrowse link
G Tyms thymidylate synthetase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TYMS mRNA CTD PMID:22101062 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of UFD1 mRNA CTD PMID:22101062 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of VTCN1 mRNA CTD PMID:22101062 NCBI chr 2:203,200,435...203,274,264
Ensembl chr 2:203,200,427...203,276,142
JBrowse link
G Wdr26 WD repeat domain 26 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of WDR26 mRNA CTD PMID:22101062 NCBI chr13:99,493,117...99,532,775
Ensembl chr13:99,493,120...99,531,959
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of WT1 mRNA CTD PMID:22101062 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Yipf3 Yip1 domain family, member 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of YIPF3 mRNA CTD PMID:22101062 NCBI chr 9:17,115,308...17,120,659
Ensembl chr 9:17,115,343...17,120,677
JBrowse link
G Yipf5 Yip1 domain family, member 5 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of YIPF5 mRNA CTD PMID:22101062 NCBI chr18:33,401,103...33,436,885
Ensembl chr18:33,401,106...33,434,775
JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of ZYG11B mRNA CTD PMID:22101062 NCBI chr 5:127,844,062...127,878,792
Ensembl chr 5:127,847,129...127,878,792
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            14-Deoxy-11,12-didehydroandrographolide 191
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic ester 14077
                                        lactone 5979
                                          terpene lactone 1770
                                            diterpene lactone 226
                                              14-Deoxy-11,12-didehydroandrographolide 191
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.