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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:14-Deoxy-11,12-didehydroandrographolide
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Accession:CHEBI:69808 term browser browse the term
Definition:A diterpene lactone that has formula C20H28O4.
Synonyms:related_synonym: 3-{(E)-2-[(1R,4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone;   Formula=C20H28O4;   InChI=1S/C20H28O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h5-6,9,15-17,21-22H,1,4,7-8,10-12H2,2-3H3/b6-5+/t15-,16+,17-,19+,20+/m1/s1;   InChIKey=XMJAJFVLHDIEHF-CRBRZBHVSA-N;   SMILES=[H][C@]12CCC(=C)[C@@H](\\C=C\\C3=CCOC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO
 xref_mesh: MESH:C495626
 xref: PMID:21598983


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14-Deoxy-11,12-didehydroandrographolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AAAS mRNA CTD PMID:22101062 NCBI chr 7:133,464,315...133,483,961
Ensembl chr 7:133,464,315...133,483,961
JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ACP2 mRNA CTD PMID:22101062 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680
JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ADRM1 mRNA CTD PMID:22101062 NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
JBrowse link
G Ajuba ajuba LIM protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AJUBA mRNA CTD PMID:22101062 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AK1 mRNA CTD PMID:22101062 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Akap1 A-kinase anchoring protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AKAP1 mRNA CTD PMID:22101062 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of AKR7A2 mRNA CTD PMID:22101062 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ALDOA mRNA CTD PMID:22101062 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Ank3 ankyrin 3 decreases expression
increases expression
ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ANK3 mRNA
14-deoxy-11,12-didehydroandrographolide results in increased expression of ANK3 mRNA
CTD PMID:22101062 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ARHGAP5 mRNA CTD PMID:22101062 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
JBrowse link
G Arid4a AT-rich interaction domain 4A increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of ARID4A mRNA CTD PMID:22101062 NCBI chr 6:89,522,463...89,593,868
Ensembl chr 6:89,522,442...89,593,510
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ARIH2 mRNA CTD PMID:22101062 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ASXL1 mRNA CTD PMID:22101062 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ATP5F1D mRNA CTD PMID:22101062 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ATP6V0D1 mRNA CTD PMID:22101062 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ATP6V1C1 mRNA CTD PMID:22101062 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of BAG1 mRNA CTD PMID:22101062 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bloc1s1 biogenesis of lysosomal organelles complex-1, subunit 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of BLOC1S1 mRNA CTD PMID:22101062 NCBI chr 7:1,347,495...1,351,103
Ensembl chr 7:1,340,934...1,351,558
JBrowse link
G Ca12 carbonic anhydrase 12 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CA12 mRNA CTD PMID:22101062 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CAPRIN1 mRNA CTD PMID:22101062 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] CTD PMID:27089844 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:27089844 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnb1ip1 cyclin B1 interacting protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CCNB1IP1 mRNA CTD PMID:22101062 NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CCND1 mRNA
14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCND1 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CCND1 protein]]
CTD PMID:22101062 PMID:30248417 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CCND3 mRNA CTD PMID:22101062 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNE1 protein] CTD PMID:30248417 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccng2 cyclin G2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CCNG2 mRNA CTD PMID:22101062 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CDC37 mRNA CTD PMID:22101062 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CDK2 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CDK2 protein]] CTD PMID:30248417 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CDK6 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CDK6 protein]] CTD PMID:30248417 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CDKN1B mRNA CTD PMID:22101062 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] promotes the reaction [CREB1 protein binds to CEBPB promoter]]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPB mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CEBPB protein] CTD PMID:30248417 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cenps centromere protein S decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CENPS mRNA CTD PMID:22101062 NCBI chr 5:159,563,917...159,573,534 JBrowse link
G Cfl1 cofilin 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CFL1 mRNA CTD PMID:22101062 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CHD2 mRNA CTD PMID:22101062 NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502
JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CHTF8 mRNA CTD PMID:22101062 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CLPTM1 mRNA CTD PMID:22101062 NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092
JBrowse link
G Cope COPI coat complex subunit epsilon decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of COPE mRNA CTD PMID:22101062 NCBI chr16:19,114,871...19,125,527
Ensembl chr16:19,114,871...19,128,907
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] promotes the reaction [CREB1 protein binds to CEBPB promoter]]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of CREB1 protein] CTD PMID:30248417 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of CXCL12 mRNA CTD PMID:22101062 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of CYP1A1 mRNA
beta-Naphthoflavone promotes the reaction [14-deoxy-11,12-didehydroandrographolide results in increased expression of CYP1A1 mRNA]
CTD PMID:21963808 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DCAF6 mRNA CTD PMID:22101062 NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of DDIT3 mRNA CTD PMID:22101062 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of DDIT4 mRNA CTD PMID:22101062 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DHFR mRNA CTD PMID:22101062 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Drg2 developmentally regulated GTP binding protein 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DRG2 mRNA CTD PMID:22101062 NCBI chr10:45,255,501...45,269,971
Ensembl chr10:45,255,507...45,269,969
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of DUT mRNA CTD PMID:22101062 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of EIF4EBP1 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of EIF4EBP1 protein]] CTD PMID:30248417 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of ELOVL2 mRNA CTD PMID:22101062 NCBI chr17:23,544,520...23,584,855
Ensembl chr17:23,544,568...23,584,848
JBrowse link
G Eno1 enolase 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ENO1 mRNA CTD PMID:22101062 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of EWSR1 mRNA CTD PMID:22101062 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein] CTD PMID:30248417 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo8 F-box protein 8 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FBXO8 mRNA CTD PMID:22101062 NCBI chr16:33,665,305...33,711,215
Ensembl chr16:33,665,306...33,711,272
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FEN1 mRNA CTD PMID:22101062 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fibp FGF1 intracellular binding protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FIBP mRNA CTD PMID:22101062 NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FKBP1A mRNA CTD PMID:22101062 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Flcn folliculin increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FLCN mRNA CTD PMID:22101062 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fnip1 folliculin interacting protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FNIP1 mRNA CTD PMID:22101062 NCBI chr10:38,567,728...38,650,824 JBrowse link
G Folr1 folate receptor alpha increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FOLR1 mRNA CTD PMID:22101062 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Fus FUS RNA binding protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of FUS mRNA CTD PMID:22101062 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
JBrowse link
G Fzd7 frizzled class receptor 7 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of FZD7 mRNA CTD PMID:22101062 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GADD45A mRNA CTD PMID:22101062 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gas5 growth arrest specific 5 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GAS5 mRNA CTD PMID:22101062 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gfus GDP-L-fucose synthase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GFUS mRNA CTD PMID:22101062 NCBI chr 7:107,612,087...107,617,005
Ensembl chr 7:107,612,094...107,616,948
JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GNE mRNA CTD PMID:22101062 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499
JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GPAA1 mRNA CTD PMID:22101062 NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484
JBrowse link
G Gps1 G protein pathway suppressor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GPS1 mRNA CTD PMID:22101062 NCBI chr10:106,050,323...106,055,407
Ensembl chr10:106,050,388...106,055,412
JBrowse link
G Gps2 G protein pathway suppressor 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of GPS2 mRNA CTD PMID:22101062 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein] CTD PMID:30248417 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gulp1 GULP PTB domain containing engulfment adaptor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of GULP1 mRNA CTD PMID:22101062 NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of H1-2 mRNA CTD PMID:22101062 NCBI chr17:41,391,106...41,392,611 JBrowse link
G H2bc9 H2B clustered histone 9 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of H2BC9 mRNA CTD PMID:22101062 NCBI chr17:42,470,593...42,478,605 JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HBP1 mRNA CTD PMID:22101062 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hells helicase, lymphoid specific decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HELLS mRNA CTD PMID:22101062 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HERPUD1 mRNA CTD PMID:22101062 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HGSNAT mRNA CTD PMID:22101062 NCBI chr16:66,105,233...66,137,444 JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HMGCS2 mRNA CTD PMID:22101062 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HNRNPA1 mRNA CTD PMID:22101062 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of HNRNPD mRNA CTD PMID:22101062 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786
JBrowse link
G Hoxb3 homeo box B3 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of HOXB3 mRNA CTD PMID:22101062 NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of IFRD1 mRNA CTD PMID:22101062 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of IFRD2 mRNA CTD PMID:22101062 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of IGFBP5 mRNA CTD PMID:22101062 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27089844 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Immp1l inner mitochondrial membrane peptidase subunit 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of IMMP1L mRNA CTD PMID:22101062 NCBI chr 3:92,385,329...92,450,557
Ensembl chr 3:92,385,379...92,452,313
JBrowse link
G Ints11 integrator complex subunit 11 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of INTS11 mRNA CTD PMID:22101062 NCBI chr 5:166,479,134...166,497,956
Ensembl chr 5:166,479,155...166,497,651
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ITGB1BP1 mRNA CTD PMID:22101062 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of ITPK1 mRNA CTD PMID:22101062 NCBI chr 6:121,710,750...121,844,501
Ensembl chr 6:121,710,755...121,844,107
JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of JMY mRNA CTD PMID:22101062 NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of KCNK2 mRNA CTD PMID:22101062 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of LGR4 mRNA CTD PMID:22101062 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lhx2 LIM homeobox 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of LHX2 mRNA CTD PMID:22101062 NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908
JBrowse link
G Lmna lamin A/C decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of LMNA mRNA CTD PMID:22101062 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of H2AC6 mRNA CTD PMID:22101062 NCBI chr17:42,707,863...42,708,420 JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of LRRN3 mRNA CTD PMID:22101062 NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of LSR mRNA CTD PMID:22101062 NCBI chr 1:86,185,769...86,201,952
Ensembl chr 1:86,186,431...86,201,952
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MANF mRNA CTD PMID:22101062 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK1 protein] CTD PMID:30248417 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk13 mitogen activated protein kinase 13 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MAPK13 mRNA CTD PMID:22101062 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:30248417 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MCL1 mRNA CTD PMID:22101062 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MCM2 mRNA CTD PMID:22101062 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MCM3 mRNA CTD PMID:22101062 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Msto1 misato mitochondrial distribution and morphology regulator 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MSTO1 mRNA CTD PMID:22101062 NCBI chr 2:174,305,945...174,310,230
Ensembl chr 2:174,301,861...174,310,216
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MTSS1 mRNA CTD PMID:22101062 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of MXI1 mRNA CTD PMID:22101062 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MYBL2 mRNA CTD PMID:22101062 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of MYC mRNA CTD PMID:22101062 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nabp2 nucleic acid binding protein 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of NABP2 mRNA CTD PMID:22101062 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NAMPT mRNA CTD PMID:22101062 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of NBL1 mRNA CTD PMID:22101062 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
G Nck1 NCK adaptor protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NCK1 mRNA CTD PMID:22101062 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NFAT5 mRNA CTD PMID:22101062 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nmu neuromedin U decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of NMU mRNA CTD PMID:22101062 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of NUPR1 mRNA CTD PMID:22101062 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Olfm1 olfactomedin 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of OLFM1 mRNA CTD PMID:22101062 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PAFAH1B1 mRNA CTD PMID:22101062 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Pkm pyruvate kinase M1/2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PKM mRNA CTD PMID:22101062 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plxnb2 plexin B2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PLXNB2 mRNA CTD PMID:22101062 NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of POLA1 mRNA CTD PMID:22101062 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein] CTD PMID:30248417 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PPFIA1 mRNA CTD PMID:22101062 NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PPP1CA mRNA CTD PMID:22101062 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Prcp prolylcarboxypeptidase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PRCP mRNA CTD PMID:22101062 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of PRKACA protein] CTD PMID:30248417 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkcsh protein kinase C substrate 80K-H decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PRKCSH mRNA CTD PMID:22101062 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492
JBrowse link
G Prlr prolactin receptor increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PRLR mRNA CTD PMID:22101062 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
JBrowse link
G Prrg4 proline rich and Gla domain 4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PRRG4 mRNA CTD PMID:22101062 NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
JBrowse link
G Psen2 presenilin 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PSEN2 mRNA CTD PMID:22101062 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PSMC3 mRNA CTD PMID:22101062 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of PSPC1 mRNA CTD PMID:22101062 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202
JBrowse link
G Ptprk protein tyrosine phosphatase, receptor type, K increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of PTPRK mRNA CTD PMID:22101062 NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605
JBrowse link
G Rab27b RAB27B, member RAS oncogene family increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RAB27B mRNA CTD PMID:22101062 NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180
JBrowse link
G Rangap1 RAN GTPase activating protein 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RANGAP1 mRNA CTD PMID:22101062 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438
JBrowse link
G Rbm10 RNA binding motif protein 10 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RBM10 mRNA CTD PMID:22101062 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rbm47 RNA binding motif protein 47 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RBM47 mRNA CTD PMID:22101062 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431
JBrowse link
G Rcbtb1 RCC1 and BTB domain containing protein 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RCBTB1 mRNA CTD PMID:22101062 NCBI chr15:33,319,586...33,362,421
Ensembl chr15:33,319,586...33,365,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased activity of and affects the localization of RELA protein] CTD PMID:27089844 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RFFL mRNA CTD PMID:22101062 NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Rhod ras homolog family member D decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RHOD mRNA CTD PMID:22101062 NCBI chr 1:201,708,699...201,724,405
Ensembl chr 1:201,708,699...201,722,632
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RIT1 mRNA CTD PMID:22101062 NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RORC mRNA CTD PMID:22101062 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPS6KB1 protein]; dorsomorphin inhibits the reaction [14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:30248417 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions ISO [14-deoxy-11,12-didehydroandrographolide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPTOR protein; dorsomorphin inhibits the reaction [[14-deoxy-11,12-didehydroandrographolide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RPTOR protein] CTD PMID:30248417 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of RSRC2 mRNA CTD PMID:22101062 NCBI chr12:32,839,815...32,859,820
Ensembl chr12:32,839,809...32,859,799
JBrowse link
G Rtkn rhotekin decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of RTKN mRNA CTD PMID:22101062 NCBI chr 4:115,640,801...115,657,952
Ensembl chr 4:115,640,774...115,657,952
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SCARB1 mRNA CTD PMID:22101062 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SCD1 mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SCD1 protein] CTD PMID:30248417 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SEL1L mRNA CTD PMID:22101062 NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648
JBrowse link
G Sertad2 SERTA domain containing 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SERTAD2 mRNA CTD PMID:22101062 NCBI chr14:94,733,637...94,838,200
Ensembl chr14:94,733,579...94,838,313
JBrowse link
G Sf1 splicing factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SF1 mRNA CTD PMID:22101062 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFPQ mRNA CTD PMID:22101062 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sfxn2 sideroflexin 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFXN2 mRNA CTD PMID:22101062 NCBI chr 1:245,447,014...245,459,312 JBrowse link
G Sfxn4 sideroflexin 4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFXN4 mRNA CTD PMID:22101062 NCBI chr 1:259,976,480...259,998,778
Ensembl chr 1:259,976,481...259,998,754
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SIGMAR1 mRNA CTD PMID:22101062 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
G Slc35a4 solute carrier family 35, member A4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLC35A4 mRNA CTD PMID:22101062 NCBI chr18:28,280,483...28,284,610
Ensembl chr18:28,279,750...28,284,725
JBrowse link
G Slc39a3 solute carrier family 39 member 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLC39A3 mRNA CTD PMID:22101062 NCBI chr 7:8,676,845...8,682,846
Ensembl chr 7:8,676,759...8,685,149
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLC9A3R1 mRNA CTD PMID:22101062 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Slitrk4 SLIT and NTRK-like family, member 4 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SLITRK4 mRNA CTD PMID:22101062 NCBI chr  X:142,706,495...142,718,968
Ensembl chr  X:142,706,338...142,718,575
JBrowse link
G Snf8 SNF8 subunit of ESCRT-II decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SNF8 mRNA CTD PMID:22101062 NCBI chr10:80,984,337...80,996,724
Ensembl chr10:80,984,363...80,996,734
JBrowse link
G Snx16 sorting nexin 16 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SNX16 mRNA CTD PMID:22101062 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619
JBrowse link
G Sowahc sosondowah ankyrin repeat domain family member C increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SOWAHC mRNA CTD PMID:22101062 NCBI chr20:27,195,198...27,199,664 JBrowse link
G Spire1 spire-type actin nucleation factor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SPIRE1 mRNA CTD PMID:22101062 NCBI chr18:61,041,290...61,171,670
Ensembl chr18:61,041,290...61,171,899
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SREBF1 mRNA]; 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of SREBF1 protein] CTD PMID:30248417 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srm spermidine synthase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRM mRNA CTD PMID:22101062 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srpk2 SRSF protein kinase 2 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of SRPK2 mRNA CTD PMID:22101062 NCBI chr 4:11,464,684...11,655,993
Ensembl chr 4:11,464,674...11,655,990
JBrowse link
G Srrt serrate, RNA effector molecule decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRRT mRNA CTD PMID:22101062 NCBI chr12:19,392,578...19,406,098 JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRSF1 mRNA CTD PMID:22101062 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SRSF2 mRNA CTD PMID:22101062 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of SFRS3 mRNA CTD PMID:22101062 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
JBrowse link
G Stard10 StAR-related lipid transfer domain containing 10 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of STARD10 mRNA CTD PMID:22101062 NCBI chr 1:155,722,637...155,748,007
Ensembl chr 1:155,718,389...155,747,094
JBrowse link
G Stx3 syntaxin 3 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of STX3 mRNA CTD PMID:22101062 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
JBrowse link
G Tbrg1 transforming growth factor beta regulator 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of TBRG1 mRNA CTD PMID:22101062 NCBI chr 8:37,355,274...37,362,933
Ensembl chr 8:37,354,658...37,362,930
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TCAF1 mRNA CTD PMID:22101062 NCBI chr 4:71,589,674...71,639,309
Ensembl chr 4:71,591,200...71,613,309
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of TFAP2A mRNA CTD PMID:22101062 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of TFF1 mRNA CTD PMID:22101062 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of THSD4 mRNA CTD PMID:22101062 NCBI chr 8:60,384,636...60,984,419 JBrowse link
G Tipin timeless interacting protein decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TIPIN mRNA CTD PMID:22101062 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TK1 mRNA CTD PMID:22101062 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased activity of and affects the localization of RELA protein]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; 14-deoxy-11,12-didehydroandrographolide analog inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27089844 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TP53I3 mRNA CTD PMID:22101062 NCBI chr13:69,612,605...69,655,018
Ensembl chr13:69,620,792...69,652,475
JBrowse link
G Trak2 trafficking kinesin protein 2 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TRAK2 mRNA CTD PMID:22101062 NCBI chr 9:60,348,531...60,414,036
Ensembl chr 9:60,350,012...60,413,996
JBrowse link
G Tyms thymidylate synthetase decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of TYMS mRNA CTD PMID:22101062 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of UFD1 mRNA CTD PMID:22101062 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of VTCN1 mRNA CTD PMID:22101062 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658
JBrowse link
G Wdr26 WD repeat domain 26 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of WDR26 mRNA CTD PMID:22101062 NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of WT1 mRNA CTD PMID:22101062 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Yipf3 Yip1 domain family, member 3 decreases expression ISO 14-deoxy-11,12-didehydroandrographolide results in decreased expression of YIPF3 mRNA CTD PMID:22101062 NCBI chr 9:14,730,289...14,735,644
Ensembl chr 9:14,730,284...14,735,641
JBrowse link
G Yipf5 Yip1 domain family, member 5 increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of YIPF5 mRNA CTD PMID:22101062 NCBI chr18:32,123,814...32,159,752
Ensembl chr18:32,123,842...32,157,642
JBrowse link
G Zyg11b zyg-11 family member B, cell cycle regulator increases expression ISO 14-deoxy-11,12-didehydroandrographolide results in increased expression of ZYG11B mRNA CTD PMID:22101062 NCBI chr 5:122,985,548...123,042,735
Ensembl chr 5:122,992,147...123,042,736
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            14-Deoxy-11,12-didehydroandrographolide 190
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic ester 15884
                                        lactone 11242
                                          terpene lactone 1785
                                            diterpene lactone 230
                                              14-Deoxy-11,12-didehydroandrographolide 190
paths to the root