Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:catalpol
go back to main search page
Accession:CHEBI:69797 term browser browse the term
Definition:An organic molecular entity that has formula C15H22O10.
Synonyms:related_synonym: Catalpinoside;   Catalposide, des-p-hydroxybenzoyl-;   Formula=C15H22O10;   InChI=1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1;   InChIKey=LHDWRKICQLTVDL-PZYDOOQISA-N;   SMILES=[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]1OC=C[C@@]2([H])[C@H](O)[C@]3([H])O[C@]3(CO)[C@@]12[H];   beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl,(1aS-(1a-alpha,1b-beta,2-beta,5a-beta,6-beta,6a-alpha))-
 alt_id: CHEBI:3464
 xref: CAS:2415-24-9;   KEGG:C09773;   KNApSAcK:C00003075
 xref_mesh: MESH:C078040
 xref: PMID:21568305



show annotations for term's descendants           Sort by:
catalpol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO catalpol inhibits the reaction [Galactose results in increased activity of ACHE protein] CTD PMID:23612000 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]] CTD PMID:37436358 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]] CTD PMID:37436358 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO catalpol inhibits the reaction [Galactose results in decreased activity of CHAT protein] CTD PMID:23612000 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO catalpol inhibits the reaction [Galactose results in decreased expression of CHRM1 protein] CTD PMID:23612000 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Cst3 cystatin C multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of CST3 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of CST3 protein] CTD PMID:37436358 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]; catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]] CTD PMID:30682494 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of HAVCR1 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of HAVCR1 protein] CTD PMID:37436358 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]]; [triptolide co-treated with catalpol co-treated with Saponins] results in increased expression of HMOX1 protein; [triptolide co-treated with catalpol] results in increased expression of HMOX1 protein; catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]]
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]
CTD PMID:30682494 PMID:37436358 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma multiple interactions ISO catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]; catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased chemical synthesis of Reactive Oxygen Species]; catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TLR4 mRNA]; catalpol results in decreased susceptibility to [Lipopolysaccharides co-treated with IFNG protein] CTD PMID:23164921 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO catalpol inhibits the reaction [Galactose results in increased expression of IL1B protein] CTD PMID:23612000 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:37436358 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mir140 microRNA 140 multiple interactions ISO catalpol inhibits the reaction [Diabetic Cardiomyopathies decrease the expression of Mir140 RNA in myocardium] RGD PMID:31078585 RGD:329347833 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]]; [catalpol co-treated with Saponins co-treated with triptolide] affects the localization of NFE2L2 protein; [catalpol co-treated with triptolide] affects the localization of NFE2L2 protein; [triptolide co-treated with catalpol] results in increased expression of NFE2L2 protein; catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]; catalpol inhibits the reaction [Saponins inhibits the reaction [triptolide results in decreased phosphorylation of NFE2L2 protein]]; catalpol inhibits the reaction [triptolide results in decreased expression of NFE2L2 mRNA]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; Saponins promotes the reaction [[triptolide co-treated with catalpol] results in increased expression of NFE2L2 protein]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in decreased expression of NFE2L2 mRNA]]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]]
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
CTD PMID:30682494 PMID:37436358 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA] CTD PMID:23164921 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [triptolide co-treated with catalpol] results in increased expression of NQO1 protein; catalpol promotes the reaction [[triptolide co-treated with Saponins] results in increased expression of NQO1 protein]; Saponins promotes the reaction [[triptolide co-treated with catalpol] results in increased expression of NQO1 protein] CTD PMID:30682494 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGS2 mRNA] CTD PMID:23164921 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]]; catalpol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]
CTD PMID:37436358 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO catalpol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TLR4 mRNA] CTD PMID:23164921 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; catalpol inhibits the reaction [Galactose results in increased expression of TNF protein]; catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; SIRT1 protein affects the reaction [catalpol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
CTD PMID:23612000 PMID:37436358 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            catalpol 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      p-block molecular entity 19866
                        carbon group molecular entity 19811
                          organic molecular entity 19806
                            catalpol 20
paths to the root