Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aucubin
go back to main search page
Accession:CHEBI:69796 term browser browse the term
Definition:An organic molecular entity that has formula C15H22O9.
Synonyms:related_synonym: (1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl beta-D-glucopyranoside;   Formula=C15H22O9;   InChI=1S/C15H22O9/c16-4-6-3-8(18)7-1-2-22-14(10(6)7)24-15-13(21)12(20)11(19)9(5-17)23-15/h1-3,7-21H,4-5H2/t7-,8+,9+,10+,11+,12-,13+,14-,15-/m0/s1;   InChIKey=RJWJHRPNHPHBRN-FKVJWERZSA-N;   Rhinanthin;   SMILES=[H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]1OC=C[C@@]2([H])[C@H](O)C=C(CO)[C@@]12[H]
 alt_id: CHEBI:2919
 xref: CAS:479-98-1;   KEGG:C09771;   KNApSAcK:C00003073
 xref_mesh: MESH:C006650
 xref: PMID:21568305



show annotations for term's descendants           Sort by:
aucubin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein] CTD PMID:35961541 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO aucubin results in increased phosphorylation of AKT1 protein
aucubin inhibits the reaction [Cisplatin results in increased phosphorylation of AKT1 protein]
CTD PMID:29408431 PMID:32504734 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO
EXP
aucubin results in increased expression of ALPL mRNA
aucubin results in increased expression of ALPL protein
CTD PMID:38492842 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO
EXP
aucubin results in increased expression of BGLAP protein CTD PMID:29408431 PMID:38492842 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO aucubin results in increased expression of BMP2 protein
aucubin results in increased expression of BMP2 mRNA; aucubin results in increased expression of BMP2 protein
CTD PMID:29408431 PMID:38492842 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [aucubin co-treated with Streptozocin co-treated with Dietary Fats] results in decreased cleavage of CASP1 protein
aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased cleavage of CASP1 protein]
CTD PMID:35961541 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] CTD PMID:32504734 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein] CTD PMID:32504734 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein] CTD PMID:35961541 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein] CTD PMID:35961541 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased expression of CDKN1A protein] CTD PMID:32504734 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP
ISO
aucubin results in increased expression of COL1A1 protein
aucubin results in increased expression of COL1A1 mRNA; aucubin results in increased expression of COL1A1 protein
CTD PMID:38492842 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased phosphorylation of ERN1 protein]
aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein]
CTD PMID:35961541 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased expression of and results in increased phosphorylation of FOXO3 protein] CTD PMID:32504734 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein] CTD PMID:35961541 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein] CTD PMID:35961541 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased expression of HMOX1 protein] CTD PMID:32504734 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of HSPA5 protein] CTD PMID:35961541 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Il18 interleukin 18 multiple interactions ISO aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein] CTD PMID:35961541 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B protein]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein] CTD PMID:35961541 PMID:36108984 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 mRNA]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein] CTD PMID:36108984 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression ISO aucubin results in increased expression of ITGB1 protein CTD PMID:29408431 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B protein]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 mRNA]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 protein]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of STING1 protein]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of TNF mRNA]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of TNF protein] CTD PMID:36108984 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO aucubin results in increased phosphorylation of MAPK1 protein
aucubin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK1 protein]
CTD PMID:29408431 PMID:32504734 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO aucubin results in increased phosphorylation of MAPK14 protein CTD PMID:29408431 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO aucubin results in increased phosphorylation of MAPK3 protein
aucubin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK3 protein]
CTD PMID:29408431 PMID:32504734 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO aucubin results in increased phosphorylation of MTOR protein CTD PMID:29408431 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]
aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of NLRP3 protein]
CTD PMID:35961541 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO aucubin inhibits the reaction [Streptozocin results in increased expression of NOX4 protein]
aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of NOX4 protein]
CTD PMID:35961541 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:32504734 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased expression of RELA protein] CTD PMID:32504734 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation ISO aucubin results in increased phosphorylation of RPS6KB1 protein CTD PMID:29408431 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO aucubin results in increased expression of RUNX2 mRNA; aucubin results in increased expression of RUNX2 protein CTD PMID:38492842 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Smad1 SMAD family member 1 increases expression ISO aucubin results in increased expression of SMAD1 protein CTD PMID:29408431 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad5 SMAD family member 5 increases expression ISO aucubin results in increased expression of SMAD5 protein CTD PMID:29408431 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Smad9 SMAD family member 9 increases expression ISO aucubin results in increased expression of SMAD9 protein CTD PMID:29408431 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of SNAI1 protein] CTD PMID:35961541 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO aucubin results in increased expression of SP7 protein
aucubin results in increased expression of SP7 mRNA
CTD PMID:29408431 PMID:38492842 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO
EXP
aucubin results in increased expression of SPP1 protein
aucubin results in increased expression of SPP1 mRNA; aucubin results in increased expression of SPP1 protein
CTD PMID:29408431 PMID:38492842 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO aucubin inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:32504734 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 multiple interactions ISO aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of STING1 protein] CTD PMID:36108984 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased cleavage of CASP1 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of HSPA5 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of NLRP3 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of NOX4 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of SNAI1 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of TXNIP protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased phosphorylation of ERN1 protein] CTD PMID:35961541 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of TNF mRNA]; aucubin affects the reaction [[LDLR protein affects the susceptibility to Dietary Fats] which affects the expression of TNF protein]; aucubin inhibits the reaction [Cisplatin results in increased expression of TNF protein] CTD PMID:32504734 PMID:36108984 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of TXNIP protein]
aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein]
CTD PMID:35961541 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        biochemical role 19589
          metabolite 19575
            aucubin 44
              agnuside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      p-block molecular entity 19855
                        carbon group molecular entity 19794
                          organic molecular entity 19790
                            aucubin 44
                              agnuside 0
paths to the root