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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Palbinone
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Accession:CHEBI:69584 term browser browse the term
Definition:A 16-oxo steroid that has formula C22H30O4.
Synonyms:related_synonym: 18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3beta,5alpha)-;   Formula=C22H30O4;   InChI=1S/C22H30O4/c1-19(2)13-8-11-21(4)14(20(13,3)10-9-15(19)23)7-6-12-16(24)17(25)18(26)22(12,21)5/h6-7,13-15,23-24H,8-11H2,1-5H3/t13-,14+,15-,20-,21+,22-/m0/s1;   InChIKey=KIAKLFLISZCITK-PPAUHQMUSA-N;   SMILES=[H][C@@]12CC[C@]3(C)[C@]([H])(C=CC4=C(O)C(=O)C(=O)[C@@]34C)[C@@]1(C)CC[C@H](O)C2(C)C
 xref: CAS:139954-00-0
 xref_mesh: MESH:C080910
 xref: PMID:21954959


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Palbinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein] CTD PMID:32202043 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Cat catalase multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32202043 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA] CTD PMID:32202043 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il18 interleukin 18 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:32202043 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein] CTD PMID:32202043 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA] CTD PMID:32202043 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] CTD PMID:32202043 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein] CTD PMID:32202043 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19719
      biological role 19719
        biochemical role 19312
          metabolite 19294
            Palbinone 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19579
                        carbon atom 19569
                          organic molecular entity 19569
                            organic group 18613
                              organic divalent group 18604
                                organodiyl group 18604
                                  carbonyl group 18521
                                    carbonyl compound 18521
                                      ketone 16833
                                        oxo steroid 9716
                                          16-oxo steroid 8
                                            Palbinone 8
paths to the root