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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Palbinone
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Accession:CHEBI:69584 term browser browse the term
Definition:A 16-oxo steroid that has formula C22H30O4.
Synonyms:related_synonym: 18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3beta,5alpha)-;   Formula=C22H30O4;   InChI=1S/C22H30O4/c1-19(2)13-8-11-21(4)14(20(13,3)10-9-15(19)23)7-6-12-16(24)17(25)18(26)22(12,21)5/h6-7,13-15,23-24H,8-11H2,1-5H3/t13-,14+,15-,20-,21+,22-/m0/s1;   InChIKey=KIAKLFLISZCITK-PPAUHQMUSA-N;   SMILES=[H][C@@]12CC[C@]3(C)[C@]([H])(C=CC4=C(O)C(=O)C(=O)[C@@]34C)[C@@]1(C)CC[C@H](O)C2(C)C
 xref: CAS:139954-00-0
 xref_mesh: MESH:C080910
 xref: PMID:21954959


show annotations for term's descendants           Sort by:
Palbinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein] CTD PMID:32202043 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cat catalase multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32202043 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA] CTD PMID:32202043 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il18 interleukin 18 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:32202043 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein] CTD PMID:32202043 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:32202043 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA] CTD PMID:32202043 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] CTD PMID:32202043 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein] CTD PMID:32202043 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        biochemical role 19496
          metabolite 19484
            Palbinone 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organochalcogen compound 19222
                                organooxygen compound 19137
                                  carbonyl compound 18858
                                    ketone 17163
                                      oxo steroid 10526
                                        16-oxo steroid 9
                                          Palbinone 9
paths to the root